---
_id: '3485'
abstract:
- lang: eng
text: 1. GABAergic interneurones differ from glutamatergic principal neurones in
their ability to discharge high-frequency trains of action potentials without
adaptation. To examine whether Na+ channel gating contributed to these differences,
Na+ currents were recorded in nucleated patches from interneurones (dentate gyrus
basket cells, BCs) and principal neurones (CA1 pyramidal cells, PCs) of rat hippocampal
slices. 2. The voltage dependence of Na+ channel activation in BCs and PCs was
similar. The slope factors of the activation curves, fitted with Boltzmann functions
raised to the third power, were 11.5 and 11.8 mV, and the mid-point potentials
were -25.1 and -23.9 mV, respectively. 3. Whereas the time course of Na+ channel
activation (-30 to +40 mV) was similar, the deactivation kinetics (-100 to -40
mV) were faster in BCs than in PCs (tail current decay time constants, 0.13 and
0.20 ms, respectively, at -40 mV). 4. Na+ channels in BCs and PCs differed in
the voltage dependence of inactivation. The slope factors of the steady-state
inactivation curves fitted with Boltzmann functions were 6.7 and 10.7 mV, and
the mid-point potentials were -58.3 and -62.9 mV, respectively. 5. The onset of
Na+ channel inactivation at -55 mV was slower in BC's than in PCs; the inactivation
time constants were 18.6 and 9.3 ms, respectively. At more positive potentials
the differences in inactivation onset were smaller. 6. The time course of recovery
of Na+ channels from inactivation induced by a 30 ms pulse was fast and mono-exponential
(τ = 2.0 ms at -120 mV) in BCs, whereas it was slower and biexponential in PCs
(τ1 = 2.0 ms and τ2 = 133 ms; amplitude contribution of the slow component, 15%).
7. We conclude that Na+ channels of BCs and PCs differ in gating properties that
contribute to the characteristic action potential patterns of the two types of
neurones.
acknowledgement: We thank Drs J. Bischofberger and J. R. P. Geiger for critically
reading the manuscript, Mrs B. Plessow-Freudenberg and K. Zipfel for technical assistance,
and Mrs B. Hillers for typing. This work was supported by the German Israeli Foundation
grant I 0352–073.01/94 to P. J.
article_processing_charge: No
article_type: original
author:
- first_name: Marco
full_name: Martina, Marco
last_name: Martina
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Martina M, Jonas PM. Functional differences in Na+ channel gating between fast-spiking
interneurones and principal neurones in rat hippocampus. Journal of Physiology.
1997;505(3):593-603. doi:10.1111/j.1469-7793.1997.593ba.x
apa: Martina, M., & Jonas, P. M. (1997). Functional differences in Na+ channel
gating between fast-spiking interneurones and principal neurones in rat hippocampus.
Journal of Physiology. Wiley-Blackwell. https://doi.org/10.1111/j.1469-7793.1997.593ba.x
chicago: Martina, Marco, and Peter M Jonas. “Functional Differences in Na+ Channel
Gating between Fast-Spiking Interneurones and Principal Neurones in Rat Hippocampus.”
Journal of Physiology. Wiley-Blackwell, 1997. https://doi.org/10.1111/j.1469-7793.1997.593ba.x.
ieee: M. Martina and P. M. Jonas, “Functional differences in Na+ channel gating
between fast-spiking interneurones and principal neurones in rat hippocampus,”
Journal of Physiology, vol. 505, no. 3. Wiley-Blackwell, pp. 593–603, 1997.
ista: Martina M, Jonas PM. 1997. Functional differences in Na+ channel gating between
fast-spiking interneurones and principal neurones in rat hippocampus. Journal
of Physiology. 505(3), 593–603.
mla: Martina, Marco, and Peter M. Jonas. “Functional Differences in Na+ Channel
Gating between Fast-Spiking Interneurones and Principal Neurones in Rat Hippocampus.”
Journal of Physiology, vol. 505, no. 3, Wiley-Blackwell, 1997, pp. 593–603,
doi:10.1111/j.1469-7793.1997.593ba.x.
short: M. Martina, P.M. Jonas, Journal of Physiology 505 (1997) 593–603.
date_created: 2018-12-11T12:03:34Z
date_published: 1997-12-15T00:00:00Z
date_updated: 2022-08-22T08:25:26Z
day: '15'
doi: 10.1111/j.1469-7793.1997.593ba.x
extern: '1'
external_id:
pmid:
- '9457638'
intvolume: ' 505'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160038/
month: '12'
oa: 1
oa_version: Published Version
page: 593 - 603
pmid: 1
publication: Journal of Physiology
publication_identifier:
issn:
- 0022-3751
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2902'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Functional differences in Na+ channel gating between fast-spiking interneurones
and principal neurones in rat hippocampus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 505
year: '1997'
...
---
_id: '3486'
abstract:
- lang: eng
text: 1. Dendritic patch-clamp recordings were obtained from mitral cells in rat
olfactory bulb slices, up to 350 μm from the soma. Simultaneous dendritic and
somatic whole-cell recordings indicated that action potentials (APs) evoked by
somatic or dendritic current injection were initiated near the soma. Both the
large amplitude (100.7 ± 1.1 mV) and the short duration (1.38 ± 0.07 ms) of the
AP were maintained as the AP propagated back into the primary mitral cell dendrites.
2. Outside-out patches isolated from mitral cell dendrites contained voltage-gated
Na+ channels (peak conductance density, 90 pS μm-2 at -10 mV). When an AP was
used as a somatic voltage-clamp command in the presence of 1 μM tetrodotoxin (TTX),
the amplitude of the dendritic potential was attenuated to 48 ± 14 mV. This shows
that dendritic Na+ channels support the active back-propagation of APs. 3. Dendritic
patches contained voltage-gated K+ channels with high density (conductance density,
513 pS μm-2 at 30 mV. Dendritic K+ currents were reduced to 35% by 1 mM external
tetraethylammonium chloride (TEACl). When an AP was used as a somatic voltage
clamp command in the presence of TEACl, the dendritic potential was markedly prolonged.
This indicates that dendritic K+ channels mediate the fast repolarization of dendritic
APs. 4. We conclude that voltage gated Na+ and K+ channels support dendritic APs
with large amplitudes and short durations that may trigger fast transmitter release
at dendrodendritic synapses in the olfactory bulb.
acknowledgement: We thank Drs J. R. P. Geiger, M. Martina, and D. Schild for critically
reading the manuscript, and Mrs B. Plessow-Freudenberg for technical assistance.
This work was supported by DFG grant BI 642/1-1 and German Israeli Foundation grant
I 0352-073.01/94.
article_processing_charge: No
article_type: original
author:
- first_name: Joseph
full_name: Bischofberger, Joseph
last_name: Bischofberger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Bischofberger J, Jonas PM. Action potential propagation into the presynaptic
dendrites of rat mitral cells. Journal of Physiology. 1997;504(Pt 2):359-365.
doi:10.1111/j.1469-7793.1997.359be.x
apa: Bischofberger, J., & Jonas, P. M. (1997). Action potential propagation
into the presynaptic dendrites of rat mitral cells. Journal of Physiology.
Wiley-Blackwell. https://doi.org/10.1111/j.1469-7793.1997.359be.x
chicago: Bischofberger, Joseph, and Peter M Jonas. “Action Potential Propagation
into the Presynaptic Dendrites of Rat Mitral Cells.” Journal of Physiology.
Wiley-Blackwell, 1997. https://doi.org/10.1111/j.1469-7793.1997.359be.x.
ieee: J. Bischofberger and P. M. Jonas, “Action potential propagation into the presynaptic
dendrites of rat mitral cells,” Journal of Physiology, vol. 504, no. Pt
2. Wiley-Blackwell, pp. 359–365, 1997.
ista: Bischofberger J, Jonas PM. 1997. Action potential propagation into the presynaptic
dendrites of rat mitral cells. Journal of Physiology. 504(Pt 2), 359–365.
mla: Bischofberger, Joseph, and Peter M. Jonas. “Action Potential Propagation into
the Presynaptic Dendrites of Rat Mitral Cells.” Journal of Physiology,
vol. 504, no. Pt 2, Wiley-Blackwell, 1997, pp. 359–65, doi:10.1111/j.1469-7793.1997.359be.x.
short: J. Bischofberger, P.M. Jonas, Journal of Physiology 504 (1997) 359–365.
date_created: 2018-12-11T12:03:35Z
date_published: 1997-10-15T00:00:00Z
date_updated: 2022-08-19T12:02:21Z
day: '15'
doi: 10.1111/j.1469-7793.1997.359be.x
extern: '1'
external_id:
pmid:
- '9365910'
intvolume: ' 504'
issue: Pt 2
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1159916/
month: '10'
oa: 1
oa_version: Published Version
page: 359 - 365
pmid: 1
publication: Journal of Physiology
publication_identifier:
issn:
- 0022-3751
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2901'
quality_controlled: '1'
status: public
title: Action potential propagation into the presynaptic dendrites of rat mitral cells
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 504
year: '1997'
...
---
_id: '3541'
abstract:
- lang: eng
text: 'The contribution of the various hippocampal regions to the maintenance of
epileptic activity, induced by stimulation of the perforant path or commissural
system, was examined in the awake rat. Combination of multiple-site recordings
with silicon probes, current source density analysis and unit recordings allowed
for a high spatial resolution of the field events. Following perforant path stimulation,
seizures began in the dentate gyrus, followed by events in the CA3-CA1 regions.
After commissural stimulation, rhythmic bursts in the CA3-CA1 circuitry preceded
the activation of the dentate gyrus. Correlation of events in the different subregions
indicated that the sustained rhythmic afterdischarge (2-6 Hz) could not be explained
by a cycle-by-cycle excitation of principal cell populations in the hippocampal-entorhinal
loop. The primary afterdischarge always terminated in the CA1 region, followed
by the dentate gyrus, CA3 region and the entorhinal cortex. The duration and pattern
of the hippocampal afterdischarge was essentially unaffected by removal of the
entorhinal cortex. The emergence of large population spike bursts coincided with
a decreased discharge of interneurons in both CAI and hilar regions. The majority
of hilar interneurons displayed a strong amplitude decrement prior to the onset
of population spike phase of the afterdischarge. These findings suggest that (i)
afterdischarges can independently arise in the CA3-CA1 and entorhinal-dentate
gyrus circuitries, (ii) reverberation of excitation in the hippocampal-entorhinal
loop is not critical for the maintenance of afterdischarges and (iii) decreased
activity of the interneuronal network may release population bursting of principal
cells. '
acknowledgement: We thank K. Wise and J. Hetke for providing us the silicon probes,
J. J. Chrobak, S. L-W. Leung, G. G. Somjen and R. D. Traub for their comments on
the manuscript. This work was supported by NINDS (NS34994; 1P41RR09754; NS33310)
and the Whitehall Foundation. M. Penttonen was a visiting scholar at Rutgers University,
supported by the Finnish Academy of Sciences and the A. I. Virtanen Institute.
article_processing_charge: No
article_type: original
author:
- first_name: Anatol
full_name: Bragin, Anatol
last_name: Bragin
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: Markku
full_name: Penttonen, Markku
last_name: Penttonen
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
citation:
ama: 'Bragin A, Csicsvari JL, Penttonen M, Buzsáki G. Epileptic afterdischarge in
the hippocampal-entorhinal system: Current source density and unit studies. Neuroscience.
1997;76(4):1187-1203. doi:10.1016/S0306-4522(96)00446-0'
apa: 'Bragin, A., Csicsvari, J. L., Penttonen, M., & Buzsáki, G. (1997). Epileptic
afterdischarge in the hippocampal-entorhinal system: Current source density and
unit studies. Neuroscience. Elsevier. https://doi.org/10.1016/S0306-4522(96)00446-0'
chicago: 'Bragin, Anatol, Jozsef L Csicsvari, Markku Penttonen, and György Buzsáki.
“Epileptic Afterdischarge in the Hippocampal-Entorhinal System: Current Source
Density and Unit Studies.” Neuroscience. Elsevier, 1997. https://doi.org/10.1016/S0306-4522(96)00446-0.'
ieee: 'A. Bragin, J. L. Csicsvari, M. Penttonen, and G. Buzsáki, “Epileptic afterdischarge
in the hippocampal-entorhinal system: Current source density and unit studies,”
Neuroscience, vol. 76, no. 4. Elsevier, pp. 1187–1203, 1997.'
ista: 'Bragin A, Csicsvari JL, Penttonen M, Buzsáki G. 1997. Epileptic afterdischarge
in the hippocampal-entorhinal system: Current source density and unit studies.
Neuroscience. 76(4), 1187–1203.'
mla: 'Bragin, Anatol, et al. “Epileptic Afterdischarge in the Hippocampal-Entorhinal
System: Current Source Density and Unit Studies.” Neuroscience, vol. 76,
no. 4, Elsevier, 1997, pp. 1187–203, doi:10.1016/S0306-4522(96)00446-0.'
short: A. Bragin, J.L. Csicsvari, M. Penttonen, G. Buzsáki, Neuroscience 76 (1997)
1187–1203.
date_created: 2018-12-11T12:03:52Z
date_published: 1997-01-15T00:00:00Z
date_updated: 2022-08-19T11:53:06Z
day: '15'
doi: 10.1016/S0306-4522(96)00446-0
extern: '1'
external_id:
pmid:
- '9027878'
intvolume: ' 76'
issue: '4'
language:
- iso: eng
month: '01'
oa_version: None
page: 1187 - 1203
pmid: 1
publication: Neuroscience
publication_identifier:
issn:
- 0306-4522
publication_status: published
publisher: Elsevier
publist_id: '2844'
quality_controlled: '1'
status: public
title: 'Epileptic afterdischarge in the hippocampal-entorhinal system: Current source
density and unit studies'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 76
year: '1997'
...
---
_id: '3630'
abstract:
- lang: eng
text: This paper derives the long-term effective size, Ne, for a general model of
population subdivision, allowing for differential deme fitness, variable emigration
and immigration rates, extinction, colonization, and correlations across generations
in these processes. We show that various long-term measures of Ne are equivalent.
The effective size of a metapopulation can be expressed in a variety of ways.
At a demographic equilibrium, Ne can be derived from the demography by combining
information about the ultimate contribution of each deme to the future genetic
make-up of the population and Wright's FST's. The effective size is given by Ne
= 1/(1 + var (upsilon) ((1 - FST)/Nin), where n is the number of demes, theta
i is the eventual contribution of individuals in deme i to the whole population
(scaled such that sigma theta i = n), and < > denotes an average weighted
by theta i. This formula is applied to a catastrophic extinction model (where
sites are either empty or at carrying capacity) and to a metapopulation model
with explicit dynamics, where extinction is caused by demographic stochasticity
and by chaos. Contrary to the expectation from the standard island model, the
usual effect of population subdivision is to decrease the effective size relative
to a panmictic population living on the same resource.
acknowledgement: This paper has benefited greatly from the kind efforts oF ARMANDO
CABALLERO, PETER KEIGHTLEY, BEATE NÜRNBERCER and SALLY OTTO in reading and discussing
the manuscript. We also thank MONTY SLATKIN and three anonymous reviewers for their
helpful comments. One of these reviewers in particular greatly improved this paper.
The work reported here was supported by a grant from the Science and Engineering
Research Council (U.R) and the Darwin Trust of Edinburgh, as well as by the Natural
Sciences and Engineering Research Council (Canada).
article_processing_charge: No
article_type: original
author:
- first_name: Michael
full_name: Whitlock, Michael
last_name: Whitlock
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Whitlock M, Barton NH. The effective size of a subdivided population. Genetics.
1997;146(1):427-441. doi:10.1093/genetics/146.1.427
apa: Whitlock, M., & Barton, N. H. (1997). The effective size of a subdivided
population. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/146.1.427
chicago: Whitlock, Michael, and Nicholas H Barton. “The Effective Size of a Subdivided
Population.” Genetics. Genetics Society of America, 1997. https://doi.org/10.1093/genetics/146.1.427.
ieee: M. Whitlock and N. H. Barton, “The effective size of a subdivided population,”
Genetics, vol. 146, no. 1. Genetics Society of America, pp. 427–441, 1997.
ista: Whitlock M, Barton NH. 1997. The effective size of a subdivided population.
Genetics. 146(1), 427–441.
mla: Whitlock, Michael, and Nicholas H. Barton. “The Effective Size of a Subdivided
Population.” Genetics, vol. 146, no. 1, Genetics Society of America, 1997,
pp. 427–41, doi:10.1093/genetics/146.1.427.
short: M. Whitlock, N.H. Barton, Genetics 146 (1997) 427–441.
date_created: 2018-12-11T12:04:20Z
date_published: 1997-05-01T00:00:00Z
date_updated: 2022-08-19T10:01:10Z
day: '01'
doi: 10.1093/genetics/146.1.427
extern: '1'
external_id:
pmid:
- '9136031 '
intvolume: ' 146'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://academic.oup.com/genetics/article/146/1/427/6053913
month: '05'
oa: 1
oa_version: Published Version
page: 427 - 441
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '2753'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The effective size of a subdivided population
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 146
year: '1997'
...
---
_id: '3631'
abstract:
- lang: eng
text: In spatially heterogeneous environments, natural selection for maintenance
of adaptation to habitats that contribute little to the population's reproduction
is weak. In this paper we model a mechanism that can result in loss of fitness
in such marginal habitats, and thus lead to specialisation on the main habitat.
It involves accumulation of mutations that are deleterious in the marginal habitat
but neutral or nearly so in the main habitat (mutations deleterious in the main
habitat and neutral in the marginal habitat have a negligible influence). If the
contribution of the marginal habitat to total reproduction in the absence of the
mutations is less than a threshold value, selection is too weak to counter accumulation
of such mutations. A positive feedback then results in loss of fitness in the
marginal habitat. This mechanism does not require antagonistic pleiotropy in adaptation
to different habitats, although antagonistic pleiotropy facilitates the mutational
collapse of fitness in the marginal habitat. We suggest that deleterious mutations
with habitat-specific expression may play a role in the evolution of ecological
specialisation and promote evolutionary conservatism of ecological niches.
article_processing_charge: No
article_type: original
author:
- first_name: Tadeusz
full_name: Kawecki, Tadeusz
last_name: Kawecki
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: James
full_name: Fry, James
last_name: Fry
citation:
ama: Kawecki T, Barton NH, Fry J. Mutational collapse of fitness in marginal habitats
and the evolution of ecological specialisation. Journal of Evolutionary Biology.
1997;10(3):407-430. doi:10.1046/j.1420-9101.1997.10030407.x
apa: Kawecki, T., Barton, N. H., & Fry, J. (1997). Mutational collapse of fitness
in marginal habitats and the evolution of ecological specialisation. Journal
of Evolutionary Biology. Wiley-Blackwell. https://doi.org/10.1046/j.1420-9101.1997.10030407.x
chicago: Kawecki, Tadeusz, Nicholas H Barton, and James Fry. “Mutational Collapse
of Fitness in Marginal Habitats and the Evolution of Ecological Specialisation.”
Journal of Evolutionary Biology. Wiley-Blackwell, 1997. https://doi.org/10.1046/j.1420-9101.1997.10030407.x.
ieee: T. Kawecki, N. H. Barton, and J. Fry, “Mutational collapse of fitness in marginal
habitats and the evolution of ecological specialisation,” Journal of Evolutionary
Biology, vol. 10, no. 3. Wiley-Blackwell, pp. 407–430, 1997.
ista: Kawecki T, Barton NH, Fry J. 1997. Mutational collapse of fitness in marginal
habitats and the evolution of ecological specialisation. Journal of Evolutionary
Biology. 10(3), 407–430.
mla: Kawecki, Tadeusz, et al. “Mutational Collapse of Fitness in Marginal Habitats
and the Evolution of Ecological Specialisation.” Journal of Evolutionary Biology,
vol. 10, no. 3, Wiley-Blackwell, 1997, pp. 407–30, doi:10.1046/j.1420-9101.1997.10030407.x.
short: T. Kawecki, N.H. Barton, J. Fry, Journal of Evolutionary Biology 10 (1997)
407–430.
date_created: 2018-12-11T12:04:20Z
date_published: 1997-05-01T00:00:00Z
date_updated: 2022-08-19T09:46:51Z
day: '01'
doi: 10.1046/j.1420-9101.1997.10030407.x
extern: '1'
intvolume: ' 10'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1420-9101.1997.10030407.x
month: '05'
oa: 1
oa_version: Published Version
page: 407 - 430
publication: Journal of Evolutionary Biology
publication_identifier:
issn:
- 1010-061X
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2752'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mutational collapse of fitness in marginal habitats and the evolution of ecological
specialisation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 10
year: '1997'
...
---
_id: '3632'
abstract:
- lang: eng
text: An important but controversial class of hypotheses concerning the evolution
of female preferences for extreme male mating displays involves 'indirect selection.'
Even in the absence of direct fitness effects, preference for males with high
overall fitness can spread via a genetic correlation that develops between preference
alleles and high fitness genotypes. Here we develop a quantitative expression
for the force of indirect selection that (i) applies to any female mating behavior,
(ii) is relatively insensitive to the underlying genetics, and (iii) is based
on measurable quantities. In conjunction with the limited data now available,
it suggests that the evolutionary force generated by indirect selection on preferences
is weak in absolute terms. This finding raises the possibility that direct selection
on preference genes may often be more important than indirect selection, but more
data on the quantities identified by our model and on direct selection are needed
to decide the question.
acknowledgement: We thank J. J. Bull, M. J. Ryan, M. Wade, B. Walsh, G. C. Williams,
and an anonymous reviewer for discussions and suggestions. This research was supported
by National Science Foundation Grant DEB94 – 07969, Biotechnology and Biological
Sciences Research Council Grants GRyHy09928 and GRyJy76057, and a travel grant from
the Burroughs-Wellcome Fund.
article_processing_charge: No
article_type: original
author:
- first_name: Mark
full_name: Kirkpatrick, Mark
last_name: Kirkpatrick
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Kirkpatrick M, Barton NH. The strength of indirect selection on female mating
preferences. PNAS. 1997;94(4):1282-1286. doi:10.1073/pnas.94.4.1282
apa: Kirkpatrick, M., & Barton, N. H. (1997). The strength of indirect selection
on female mating preferences. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.94.4.1282
chicago: Kirkpatrick, Mark, and Nicholas H Barton. “The Strength of Indirect Selection
on Female Mating Preferences.” PNAS. National Academy of Sciences, 1997.
https://doi.org/10.1073/pnas.94.4.1282.
ieee: M. Kirkpatrick and N. H. Barton, “The strength of indirect selection on female
mating preferences,” PNAS, vol. 94, no. 4. National Academy of Sciences,
pp. 1282–1286, 1997.
ista: Kirkpatrick M, Barton NH. 1997. The strength of indirect selection on female
mating preferences. PNAS. 94(4), 1282–1286.
mla: Kirkpatrick, Mark, and Nicholas H. Barton. “The Strength of Indirect Selection
on Female Mating Preferences.” PNAS, vol. 94, no. 4, National Academy of
Sciences, 1997, pp. 1282–86, doi:10.1073/pnas.94.4.1282.
short: M. Kirkpatrick, N.H. Barton, PNAS 94 (1997) 1282–1286.
date_created: 2018-12-11T12:04:21Z
date_published: 1997-02-18T00:00:00Z
date_updated: 2022-08-19T09:25:21Z
day: '18'
doi: 10.1073/pnas.94.4.1282
extern: '1'
external_id:
pmid:
- '9037044 '
intvolume: ' 94'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://europepmc.org/article/med/9037044
month: '02'
oa: 1
oa_version: Published Version
page: 1282 - 1286
pmid: 1
publication: PNAS
publication_identifier:
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '2751'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The strength of indirect selection on female mating preferences
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 94
year: '1997'
...
---
_id: '3633'
abstract:
- lang: eng
text: 'Gene flow from the center of a species'' range can stymie adaptation at the
periphery and prevent the range from expanding outward. We study this process
using simple models that track both demography and the evolution of a quantitative
trait in a population that is continuously distributed in space. Stabilizing selection
acts on the trait and favors an optimum phenotype that changes linearly across
the habitat. One of three outcomes is possible: the species will become extinct,
expand to fill all of the available habitat, or be confined to a limited range
in which it is significantly adapted to allow population growth. When the environment
changes rapidly in space, increased migration inhibits local adaptation and so
decreases the species'' total population size. Gene flow can cause enough maladaptation
that the peripheral half of a species'' range acts as an demographic sink. The
trait''s genetic variance has little effect on species persistence or the size
of the range when gene flow is sufficiently strong to keep population densities
far below the carrying capacity throughout the range, but it can increase the
range width and population size of an abundant species. Under some conditions,
a small parameter change can dramatically shift the balance between gene flow
and local adaptation, allowing a species with a limited range to suddenly expand
to fill all the available habitat.'
article_processing_charge: No
article_type: original
author:
- first_name: Mark
full_name: Kirkpatrick, Mark
last_name: Kirkpatrick
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Kirkpatrick M, Barton NH. Evolution of a species’ range. American Naturalist.
1997;150(1):1-23. doi:10.1086/286054
apa: Kirkpatrick, M., & Barton, N. H. (1997). Evolution of a species’ range.
American Naturalist. University of Chicago Press. https://doi.org/10.1086/286054
chicago: Kirkpatrick, Mark, and Nicholas H Barton. “Evolution of a Species’ Range.”
American Naturalist. University of Chicago Press, 1997. https://doi.org/10.1086/286054.
ieee: M. Kirkpatrick and N. H. Barton, “Evolution of a species’ range,” American
Naturalist, vol. 150, no. 1. University of Chicago Press, pp. 1–23, 1997.
ista: Kirkpatrick M, Barton NH. 1997. Evolution of a species’ range. American Naturalist.
150(1), 1–23.
mla: Kirkpatrick, Mark, and Nicholas H. Barton. “Evolution of a Species’ Range.”
American Naturalist, vol. 150, no. 1, University of Chicago Press, 1997,
pp. 1–23, doi:10.1086/286054.
short: M. Kirkpatrick, N.H. Barton, American Naturalist 150 (1997) 1–23.
date_created: 2018-12-11T12:04:21Z
date_published: 1997-07-01T00:00:00Z
date_updated: 2022-08-19T08:38:36Z
day: '01'
doi: 10.1086/286054
extern: '1'
external_id:
pmid:
- '18811273'
intvolume: ' 150'
issue: '1'
language:
- iso: eng
month: '07'
oa_version: None
page: 1 - 23
pmid: 1
publication: American Naturalist
publication_identifier:
issn:
- 0003-0147
publication_status: published
publisher: University of Chicago Press
publist_id: '2750'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evolution of a species' range
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 150
year: '1997'
...
---
_id: '4018'
abstract:
- lang: eng
text: Given a subspace X subset of or equal to R-d and a finite set S subset of
or equal to R-d, we introduce the Delaunay complex, D-X, restricted by X. Its
simplices are spanned by subsets T subset of or equal to S for which the common
intersection of Voronoi cells meets X in a non-empty set. By the nerve theorem,
boolean OR D-X and X are homotopy equivalent if all such sets are contractible.
This paper proves a sufficient condition for boolean OR D-X and X be homeomorphic.
acknowledgement: Partially supported by the National Science Foundation, under grant
ASC-200301 and the Alan T. Waterman award, grant CCR-9118874.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Nimish
full_name: Shah, Nimish
last_name: Shah
citation:
ama: Edelsbrunner H, Shah N. Triangulating topological spaces. International
Journal of Computational Geometry & Applications. 1997;7(4):365-378. doi:10.1142/S0218195997000223
apa: Edelsbrunner, H., & Shah, N. (1997). Triangulating topological spaces.
International Journal of Computational Geometry & Applications. World
Scientific Publishing. https://doi.org/10.1142/S0218195997000223
chicago: Edelsbrunner, Herbert, and Nimish Shah. “Triangulating Topological Spaces.”
International Journal of Computational Geometry & Applications. World
Scientific Publishing, 1997. https://doi.org/10.1142/S0218195997000223.
ieee: H. Edelsbrunner and N. Shah, “Triangulating topological spaces,” International
Journal of Computational Geometry & Applications, vol. 7, no. 4. World
Scientific Publishing, pp. 365–378, 1997.
ista: Edelsbrunner H, Shah N. 1997. Triangulating topological spaces. International
Journal of Computational Geometry & Applications. 7(4), 365–378.
mla: Edelsbrunner, Herbert, and Nimish Shah. “Triangulating Topological Spaces.”
International Journal of Computational Geometry & Applications, vol.
7, no. 4, World Scientific Publishing, 1997, pp. 365–78, doi:10.1142/S0218195997000223.
short: H. Edelsbrunner, N. Shah, International Journal of Computational Geometry
& Applications 7 (1997) 365–378.
date_created: 2018-12-11T12:06:28Z
date_published: 1997-01-01T00:00:00Z
date_updated: 2022-08-19T08:32:23Z
day: '01'
doi: 10.1142/S0218195997000223
extern: '1'
intvolume: ' 7'
issue: '4'
language:
- iso: eng
month: '01'
oa_version: None
page: 365 - 378
publication: International Journal of Computational Geometry & Applications
publication_identifier:
issn:
- 0925-7721
publication_status: published
publisher: World Scientific Publishing
publist_id: '2106'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Triangulating topological spaces
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 7
year: '1997'
...
---
_id: '4021'
abstract:
- lang: eng
text: A homeomorphism from R-2 to itself distorts metric quantities, such as distance
and area. We describe an algorithm that constructs homeomorphisms with prescribed
area distortion. Such homeomorphisms can be used to generate cartograms, which
are geographic maps purposely distorted so their area distributions reflects a
variable different from area, as for example population density. The algorithm
generates the homeomorphism through a sequence of local piecewise linear homeomorphic
changes. Sample results produced by the preliminary implementation of the method
are included.
acknowledgement: 'The authors thank Jack Snoeyink for bringing the cartogram problem
to their attention, and Michael McAllister for providing pointers to the literature
on cartograms. '
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Roman
full_name: Waupotitsch, Roman
last_name: Waupotitsch
citation:
ama: 'Edelsbrunner H, Waupotitsch R. A combinatorial approach to cartograms. Computational
Geometry: Theory and Applications. 1997;7(5-6):343-360. doi:10.1016/S0925-7721(96)00006-5'
apa: 'Edelsbrunner, H., & Waupotitsch, R. (1997). A combinatorial approach to
cartograms. Computational Geometry: Theory and Applications. Elsevier.
https://doi.org/10.1016/S0925-7721(96)00006-5'
chicago: 'Edelsbrunner, Herbert, and Roman Waupotitsch. “A Combinatorial Approach
to Cartograms.” Computational Geometry: Theory and Applications. Elsevier,
1997. https://doi.org/10.1016/S0925-7721(96)00006-5.'
ieee: 'H. Edelsbrunner and R. Waupotitsch, “A combinatorial approach to cartograms,”
Computational Geometry: Theory and Applications, vol. 7, no. 5–6. Elsevier,
pp. 343–360, 1997.'
ista: 'Edelsbrunner H, Waupotitsch R. 1997. A combinatorial approach to cartograms.
Computational Geometry: Theory and Applications. 7(5–6), 343–360.'
mla: 'Edelsbrunner, Herbert, and Roman Waupotitsch. “A Combinatorial Approach to
Cartograms.” Computational Geometry: Theory and Applications, vol. 7, no.
5–6, Elsevier, 1997, pp. 343–60, doi:10.1016/S0925-7721(96)00006-5.'
short: 'H. Edelsbrunner, R. Waupotitsch, Computational Geometry: Theory and Applications
7 (1997) 343–360.'
date_created: 2018-12-11T12:06:29Z
date_published: 1997-04-01T00:00:00Z
date_updated: 2022-08-19T08:12:03Z
day: '01'
doi: 10.1016/S0925-7721(96)00006-5
extern: '1'
intvolume: ' 7'
issue: 5-6
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.sciencedirect.com/science/article/pii/S0925772196000065
month: '04'
oa: 1
oa_version: Published Version
page: 343 - 360
popular_science: '1'
publication: 'Computational Geometry: Theory and Applications'
publication_identifier:
issn:
- 0925-7721
publication_status: published
publisher: Elsevier
publist_id: '2105'
status: public
title: A combinatorial approach to cartograms
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 7
year: '1997'
...
---
_id: '4022'
abstract:
- lang: eng
text: A halving hyperplane of a set S of n points in R(d) contains d affinely independent
points of S so that equally many of the points off the hyperplane lie in each
of the two half-spaces. We prove bounds on the number of halving hyperplanes under
the condition that the ratio of largest over smallest distance between any two
points is at most delta n(1/d), delta some constant. Such a set S is called dense.
In d = 2 dimensions the number of halving lines for a dense set can be as much
as Omega(n log n), and it cannot exceed O (n(5/4)/log* n). The upper bound improves
over the current best bound of O (n(3/2)/log* n) which holds more generally without
any density assumption. In d = 3 dimensions we show that O (n(7/3)) is an upper
bound on the number of halving planes for a dense set, The proof is based on a
metric argument that can be extended to d greater than or equal to 4 dimensions,
where it leads to O (n(d-2/d)) as an upper bound for the number of halving hyperplanes.
acknowledgement: Partially supported by the National Science Foundation, under Grant
ASC-9200301 and the Alan T. Waterman award, Grant CCR-9118874.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Pavel
full_name: Valtr, Pavel
last_name: Valtr
- first_name: Emo
full_name: Welzl, Emo
last_name: Welzl
citation:
ama: Edelsbrunner H, Valtr P, Welzl E. Cutting dense point sets in half. Discrete
& Computational Geometry. 1997;17(3):243-255. doi:10.1007/PL00009291
apa: Edelsbrunner, H., Valtr, P., & Welzl, E. (1997). Cutting dense point sets
in half. Discrete & Computational Geometry. Springer. https://doi.org/10.1007/PL00009291
chicago: Edelsbrunner, Herbert, Pavel Valtr, and Emo Welzl. “Cutting Dense Point
Sets in Half.” Discrete & Computational Geometry. Springer, 1997. https://doi.org/10.1007/PL00009291.
ieee: H. Edelsbrunner, P. Valtr, and E. Welzl, “Cutting dense point sets in half,”
Discrete & Computational Geometry, vol. 17, no. 3. Springer, pp. 243–255,
1997.
ista: Edelsbrunner H, Valtr P, Welzl E. 1997. Cutting dense point sets in half.
Discrete & Computational Geometry. 17(3), 243–255.
mla: Edelsbrunner, Herbert, et al. “Cutting Dense Point Sets in Half.” Discrete
& Computational Geometry, vol. 17, no. 3, Springer, 1997, pp. 243–55,
doi:10.1007/PL00009291.
short: H. Edelsbrunner, P. Valtr, E. Welzl, Discrete & Computational Geometry
17 (1997) 243–255.
date_created: 2018-12-11T12:06:29Z
date_published: 1997-04-01T00:00:00Z
date_updated: 2022-08-18T14:08:38Z
day: '01'
doi: 10.1007/PL00009291
extern: '1'
intvolume: ' 17'
issue: '3'
language:
- iso: eng
month: '04'
oa_version: None
page: 243 - 255
publication: Discrete & Computational Geometry
publication_identifier:
issn:
- 0179-5376
publication_status: published
publisher: Springer
publist_id: '2103'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cutting dense point sets in half
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 17
year: '1997'
...
---
_id: '4023'
abstract:
- lang: eng
text: Let B be a finite pseudodisk collection in the plane. By the principle of
inclusion-exclusion, the area or any other measure of the union is [GRAPHICS]
We show the existence of a two-dimensional abstract simplicial complex, X subset
of or equal to 2(B), so the above relation holds even if X is substituted for
2(B). In addition, X can be embedded in R(2) SO its underlying space is homotopy
equivalent to int Boolean OR B, and the frontier of X is isomorphic to the nerve
of the set of boundary contributions.
acknowledgement: Supported by the National Science Foundation, under Grant ASC-9200301
and the Alan T. Waterman Award CCR-9118874.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Edgar
full_name: Ramos, Edgar
last_name: Ramos
citation:
ama: Edelsbrunner H, Ramos E. Inclusion-exclusion complexes for pseudodisk collections.
Discrete & Computational Geometry. 1997;17(3):287-306. doi:10.1007/PL00009295
apa: Edelsbrunner, H., & Ramos, E. (1997). Inclusion-exclusion complexes for
pseudodisk collections. Discrete & Computational Geometry. Springer.
https://doi.org/10.1007/PL00009295
chicago: Edelsbrunner, Herbert, and Edgar Ramos. “Inclusion-Exclusion Complexes
for Pseudodisk Collections.” Discrete & Computational Geometry. Springer,
1997. https://doi.org/10.1007/PL00009295.
ieee: H. Edelsbrunner and E. Ramos, “Inclusion-exclusion complexes for pseudodisk
collections,” Discrete & Computational Geometry, vol. 17, no. 3. Springer,
pp. 287–306, 1997.
ista: Edelsbrunner H, Ramos E. 1997. Inclusion-exclusion complexes for pseudodisk
collections. Discrete & Computational Geometry. 17(3), 287–306.
mla: Edelsbrunner, Herbert, and Edgar Ramos. “Inclusion-Exclusion Complexes for
Pseudodisk Collections.” Discrete & Computational Geometry, vol. 17,
no. 3, Springer, 1997, pp. 287–306, doi:10.1007/PL00009295.
short: H. Edelsbrunner, E. Ramos, Discrete & Computational Geometry 17 (1997)
287–306.
date_created: 2018-12-11T12:06:30Z
date_published: 1997-04-01T00:00:00Z
date_updated: 2022-08-18T14:39:39Z
day: '01'
doi: 10.1007/PL00009295
extern: '1'
intvolume: ' 17'
issue: '3'
language:
- iso: eng
month: '04'
oa_version: None
page: 287 - 306
publication: Discrete & Computational Geometry
publication_identifier:
issn:
- 0179-5376
publication_status: published
publisher: Springer
publist_id: '2104'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Inclusion-exclusion complexes for pseudodisk collections
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 17
year: '1997'
...
---
_id: '4174'
abstract:
- lang: eng
text: The epiphysial region of the dorsal diencephalon is the first site at which
neurogenesis occurs in the roof of the zebrafish forebrain. We show that the homeobox
containing gene floating head (flh) is required for neurogenesis to proceed in
the epiphysis. In flh(-) embryos, the first few epiphysial neurons are generated,
but beyond the 18 somite stage, neuronal production ceases. In contrast, in masterblind(-)
(mbl(-)) embryos, epiphysial neurons are generated throughout the dorsal forebrain.
We show that mbl is required to prevent the expression of flh in dorsal forebrain
cells rostral to the epiphysis. Furthermore, epiphysial neurons are not ectopically
induced in mbl(-)/flh(-) embryos, demonstrating that the epiphysial phenotype
of mbl(-) embryos is mediated by ectopic Flh activity. We propose a role for Flh
in linking the signaling pathways that regulate regional patterning to the signaling
pathways that regulate neurogenesis.
acknowledgement: 'We thank Igor DaMd. Tom Jessell, David Kimelman. Vladimir Koah,
Karen Larison. Ingvild Mikkola, Laurie Molday. and Eric Weinberg for probes and
antibod-ies: Alex Schist and Juliet Williams for help with the TUNEL tech-nique;
Dominic Delaney for analysis of the fih neural plate: Brian Gashing and Geraldine
Millard for fish care; Christian Nusslein Volhard for her support: and Corinne Houart.
Nigel Holder, and other members of the DBRC for comments on the manuscript. Electron
microscopy of the developing epiphysis cited in this study was carried out with
the help of Celeste Malinoski. funded by a grant (EY-00168)awarded to Stephen S.
Easter. This study was supported by grants from Welcome Trust to S. W. and Human
Frontier Science Program to I. M. S.W. is a Wellcome Trust Senior Research Fellow. '
article_processing_charge: No
article_type: original
author:
- first_name: Ichiro
full_name: Masai, Ichiro
last_name: Masai
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: K Anukampa
full_name: Barth, K Anukampa
last_name: Barth
- first_name: Rachel
full_name: Macdonald, Rachel
last_name: Macdonald
- first_name: Sylwia
full_name: Adamek, Sylwia
last_name: Adamek
- first_name: Stephen
full_name: Wilson, Stephen
last_name: Wilson
citation:
ama: Masai I, Heisenberg C-PJ, Barth KA, Macdonald R, Adamek S, Wilson S. Floating
head and masterblind regulate neuronal patterning in the roof of the forebrain.
Neuron. 1997;18(1):43-57. doi:10.1016/S0896-6273(01)80045-3
apa: Masai, I., Heisenberg, C.-P. J., Barth, K. A., Macdonald, R., Adamek, S., &
Wilson, S. (1997). Floating head and masterblind regulate neuronal patterning
in the roof of the forebrain. Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(01)80045-3
chicago: Masai, Ichiro, Carl-Philipp J Heisenberg, K Anukampa Barth, Rachel Macdonald,
Sylwia Adamek, and Stephen Wilson. “Floating Head and Masterblind Regulate Neuronal
Patterning in the Roof of the Forebrain.” Neuron. Elsevier, 1997. https://doi.org/10.1016/S0896-6273(01)80045-3.
ieee: I. Masai, C.-P. J. Heisenberg, K. A. Barth, R. Macdonald, S. Adamek, and S.
Wilson, “Floating head and masterblind regulate neuronal patterning in the roof
of the forebrain,” Neuron, vol. 18, no. 1. Elsevier, pp. 43–57, 1997.
ista: Masai I, Heisenberg C-PJ, Barth KA, Macdonald R, Adamek S, Wilson S. 1997.
Floating head and masterblind regulate neuronal patterning in the roof of the
forebrain. Neuron. 18(1), 43–57.
mla: Masai, Ichiro, et al. “Floating Head and Masterblind Regulate Neuronal Patterning
in the Roof of the Forebrain.” Neuron, vol. 18, no. 1, Elsevier, 1997,
pp. 43–57, doi:10.1016/S0896-6273(01)80045-3.
short: I. Masai, C.-P.J. Heisenberg, K.A. Barth, R. Macdonald, S. Adamek, S. Wilson,
Neuron 18 (1997) 43–57.
date_created: 2018-12-11T12:07:24Z
date_published: 1997-01-01T00:00:00Z
date_updated: 2022-08-18T14:02:49Z
day: '01'
doi: 10.1016/S0896-6273(01)80045-3
extern: '1'
external_id:
pmid:
- '9010204'
intvolume: ' 18'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.sciencedirect.com/science/article/pii/S0896627301800453?via%3Dihub
month: '01'
oa: 1
oa_version: Published Version
page: 43 - 57
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '1946'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Floating head and masterblind regulate neuronal patterning in the roof of the
forebrain
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 18
year: '1997'
...
---
_id: '4201'
abstract:
- lang: eng
text: In zebrafish, as in other vertebrates, an initially singular eye held within
the neural plate has to split during morphogenesis to allow the development of
two separated eyes. It has been suggested that anterior progression of midline
tissue within the neural plate is involved in the bilateralization of the eye
held. Mutations in the recently identified silberblick (slb) gene cause an incomplete
separation of the eyes. During gastrulation and early somitogenesis, the ventral
midline of the central nervous system (CNS) together with the underlying axial
mesendoderm is shortened and broadened in slb embryos. While in wild-type embryos
the ventral CNS midline extends to the anterior limit of the neural plate at the
end of gastrulation, there is a gap between the anterior tip of the ventral CNS
midline and the anterior edge of the neural plate in slb. To investigate the cause
for the shortening of the ventral CNS midline in slb we determined the fate of
labeled ventral CNS midline cells in wild-type and slb embryos at different stages
of development. In slb, anterior migration of ventral CNS midline cells is impaired,
which indicates that migration of these cells is needed for elongation of the
ventral CNS midline. The anterior shortening of the ventral CNS midline in slb
leads to medial instead of bilateral induction of optic stalks followed by a partial
fusion of the eyes at later developmental stages. The analysis of the sIb phenotype
indicates that anterior migration of midline cells within the neural plate is
required for proper induction and subsequent bilateralization of an initially
singular eye field. These findings may therefore provide a starting point in elucidating
the role of neural plate morphogenesis in positioning of the eyes. (C) 1997 Academic
Press.
acknowledgement: 'We thank C. Thisse and Q. Xu for the kind gift of hggl and rtk2
cDNA, respectively. We are grateful to S. Wilson and R. Warga for many valuable
comments on earlier versions of this manuscript. We also thank R. Geisler, D. Gilmour,
M. Granato, I Odenthal, F. Pellegri, S. Schulte-Merker, and F. v. Eeden for critical
reading of the manuscript. '
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Christiane
full_name: Nüsslein Volhard, Christiane
last_name: Nüsslein Volhard
citation:
ama: Heisenberg C-PJ, Nüsslein Volhard C. The function of silberblick in the positioning
of the eye anlage in the zebrafish embryo. Developmental Biology. 1997;184(1):85-94.
doi:10.1006/dbio.1997.8511
apa: Heisenberg, C.-P. J., & Nüsslein Volhard, C. (1997). The function of silberblick
in the positioning of the eye anlage in the zebrafish embryo. Developmental
Biology. Elsevier. https://doi.org/10.1006/dbio.1997.8511
chicago: Heisenberg, Carl-Philipp J, and Christiane Nüsslein Volhard. “The Function
of Silberblick in the Positioning of the Eye Anlage in the Zebrafish Embryo.”
Developmental Biology. Elsevier, 1997. https://doi.org/10.1006/dbio.1997.8511.
ieee: C.-P. J. Heisenberg and C. Nüsslein Volhard, “The function of silberblick
in the positioning of the eye anlage in the zebrafish embryo,” Developmental
Biology, vol. 184, no. 1. Elsevier, pp. 85–94, 1997.
ista: Heisenberg C-PJ, Nüsslein Volhard C. 1997. The function of silberblick in
the positioning of the eye anlage in the zebrafish embryo. Developmental Biology.
184(1), 85–94.
mla: Heisenberg, Carl-Philipp J., and Christiane Nüsslein Volhard. “The Function
of Silberblick in the Positioning of the Eye Anlage in the Zebrafish Embryo.”
Developmental Biology, vol. 184, no. 1, Elsevier, 1997, pp. 85–94, doi:10.1006/dbio.1997.8511.
short: C.-P.J. Heisenberg, C. Nüsslein Volhard, Developmental Biology 184 (1997)
85–94.
date_created: 2018-12-11T12:07:33Z
date_published: 1997-04-01T00:00:00Z
date_updated: 2022-08-18T13:54:19Z
day: '01'
doi: 10.1006/dbio.1997.8511
extern: '1'
external_id:
pmid:
- '9142986 '
intvolume: ' 184'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.sciencedirect.com/science/article/pii/S0012160697985110?via%3Dihub
month: '04'
oa: 1
oa_version: Published Version
page: 85 - 94
pmid: 1
publication: Developmental Biology
publication_identifier:
eissn:
- 0012-1606
publication_status: published
publisher: Elsevier
publist_id: '1917'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The function of silberblick in the positioning of the eye anlage in the zebrafish
embryo
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 184
year: '1997'
...
---
_id: '4284'
abstract:
- lang: eng
text: The evolutionary processes responsible for adaptation and speciation on islands
differ in several ways from those on the mainland. Most attention has been given
to the random genetic drift that arises when a population is founded from just
a few colonizing genomes. Theoretical obstacles to ‘founder effect speciation’
are discussed, together with recent proposals for avoiding them. It is argued
that although certain kinds of epistasis can facilitate the evolution of strong
reproductive isolation, this favours divergence by selection as much as by random
drift.
article_processing_charge: No
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Barton NH. Natural selection and random genetic drift as causes of evolution
on islands. In: Evolution on Islands. Oxford University Press; 1997:102-123.
doi:10.1098/rstb.1996.0073'
apa: Barton, N. H. (1997). Natural selection and random genetic drift as causes
of evolution on islands. In Evolution on islands (pp. 102–123). Oxford
University Press. https://doi.org/10.1098/rstb.1996.0073
chicago: Barton, Nicholas H. “Natural Selection and Random Genetic Drift as Causes
of Evolution on Islands.” In Evolution on Islands, 102–23. Oxford University
Press, 1997. https://doi.org/10.1098/rstb.1996.0073.
ieee: N. H. Barton, “Natural selection and random genetic drift as causes of evolution
on islands,” in Evolution on islands, Oxford University Press, 1997, pp.
102–123.
ista: 'Barton NH. 1997.Natural selection and random genetic drift as causes of evolution
on islands. In: Evolution on islands. , 102–123.'
mla: Barton, Nicholas H. “Natural Selection and Random Genetic Drift as Causes of
Evolution on Islands.” Evolution on Islands, Oxford University Press, 1997,
pp. 102–23, doi:10.1098/rstb.1996.0073.
short: N.H. Barton, in:, Evolution on Islands, Oxford University Press, 1997, pp.
102–123.
date_created: 2018-12-11T12:08:02Z
date_published: 1997-11-27T00:00:00Z
date_updated: 2022-08-18T13:04:36Z
day: '27'
doi: 10.1098/rstb.1996.0073
extern: '1'
external_id:
pmid:
- '8693020'
language:
- iso: eng
month: '11'
oa_version: None
page: 102 - 123
pmid: 1
publication: Evolution on islands
publication_identifier:
isbn:
- '9780198501718'
publication_status: published
publisher: Oxford University Press
publist_id: '1800'
quality_controlled: '1'
status: public
title: Natural selection and random genetic drift as causes of evolution on islands
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '1997'
...
---
_id: '4285'
abstract:
- lang: eng
text: One of the oldest hypotheses for the advantage of recombination is that recombination
allo rvs beneficial mutations that arise in different individuals to be placed
together on the same chromosome. Unless recombination occurs, one of the beneficial
alleles is doomed to extinction, slowing the rate at which adaptive mutations
are incorporated within a population. We model the effects of a modifier of recombination
on the fixation probability of beneficial mutations when beneficial alleles are
segregating at other loci. We find that modifier alleles that increase recombination
do increase the fixation probability of beneficial mutants and subsequently hitchhike
along as the mutants rise in frequency. The strength of selection favoring a modifier
that increases recombination is proportional to lambda(2)S delta r/r when linkage
is tight and lambda(2)S(3) delta r/N when linkage is loose, where lambda is the
beneficial mutation rate per genome per generation throughout a population of
size N, S is the average mutant effect, r is the average recombination rate, and
delta ris the amount that recombination is modified. We conclude that selection
for recombination will be substantial only if there is tight linkage within the
genome or if many loci are subject to directional selection as during periods
of rapid evolutionary change.
article_processing_charge: No
article_type: original
author:
- first_name: Sarah
full_name: Otto, Sarah
last_name: Otto
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Otto S, Barton NH. The evolution of recombination: Removing the limits to
natural selection. Genetics. 1997;147(2):879-906. doi:10.1093/genetics/147.2.879'
apa: 'Otto, S., & Barton, N. H. (1997). The evolution of recombination: Removing
the limits to natural selection. Genetics. Genetics Society of America.
https://doi.org/10.1093/genetics/147.2.879'
chicago: 'Otto, Sarah, and Nicholas H Barton. “The Evolution of Recombination: Removing
the Limits to Natural Selection.” Genetics. Genetics Society of America,
1997. https://doi.org/10.1093/genetics/147.2.879.'
ieee: 'S. Otto and N. H. Barton, “The evolution of recombination: Removing the limits
to natural selection,” Genetics, vol. 147, no. 2. Genetics Society of America,
pp. 879–906, 1997.'
ista: 'Otto S, Barton NH. 1997. The evolution of recombination: Removing the limits
to natural selection. Genetics. 147(2), 879–906.'
mla: 'Otto, Sarah, and Nicholas H. Barton. “The Evolution of Recombination: Removing
the Limits to Natural Selection.” Genetics, vol. 147, no. 2, Genetics Society
of America, 1997, pp. 879–906, doi:10.1093/genetics/147.2.879.'
short: S. Otto, N.H. Barton, Genetics 147 (1997) 879–906.
date_created: 2018-12-11T12:08:02Z
date_published: 1997-10-01T00:00:00Z
date_updated: 2022-08-18T11:36:10Z
day: '01'
doi: 10.1093/genetics/147.2.879
extern: '1'
external_id:
pmid:
- '9335621'
intvolume: ' 147'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://academic.oup.com/genetics/article/147/2/879/6054161
month: '10'
oa: 1
oa_version: Published Version
page: 879 - 906
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '1796'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The evolution of recombination: Removing the limits to natural selection'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 147
year: '1997'
...
---
_id: '4286'
abstract:
- lang: eng
text: A local barrier to gene flow will delay the spread of an advantageous allele.
Exact calculations for the deterministic case show that an allele that is favorable
when rare is delayed very little even by a strong barrier; its spread is allowed
by a time proportional to log((B/σ)√2S)/S, where B is the barrier strength, σ
the dispersal range, and fitnesses are 1:1 + S:1 + 2S. However, when there is
selection against heterozytes, such that the allele cannot increase from low frequency,
a barrier can cause a much greater delay. If gene flow is reduced below a critical
value, spread is entirely prevented. Stochastic simulations show that with additive
selection, random drift slows down the spread of the allele, below the deterministic
speed of σ√2S. The delay to the advance of an advantageous allele caused by a
strong barrier can be substantially increased by random drift and increases with
B/(2Sρσ2) in a one-dimensional habitat of density ρ. However, with selection against
heterozygotes, drift can facilitate the spread and can free an allele that would
otherwise be trapped indefinitely by a strong barrier. We discuss the implications
of these results for the evolution of chromosome rearrangements.
acknowledgement: We are specially grateful to H. C. HAUFFE for allowing us to present
her unpublished data. B. NURNBERGER, J. B. SEARLE, H. C. HAUFFE, S. BAIRD, L. KRUUK
and two anonymous referees gave constructive comments on the manuscript. The work
was supported by the European Union (Human Capital and Mobility Contract No. RB4050PL922765.
article_processing_charge: No
article_type: original
author:
- first_name: Jaroslav
full_name: Piálek, Jaroslav
last_name: Piálek
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Piálek J, Barton NH. The spread of an advantageous allele across a barrier:
the effects of random drift and selection against heterozygotes. Genetics.
1997;145(2):493-504. doi:10.1093/genetics/145.2.493'
apa: 'Piálek, J., & Barton, N. H. (1997). The spread of an advantageous allele
across a barrier: the effects of random drift and selection against heterozygotes.
Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/145.2.493'
chicago: 'Piálek, Jaroslav, and Nicholas H Barton. “The Spread of an Advantageous
Allele across a Barrier: The Effects of Random Drift and Selection against Heterozygotes.”
Genetics. Genetics Society of America, 1997. https://doi.org/10.1093/genetics/145.2.493.'
ieee: 'J. Piálek and N. H. Barton, “The spread of an advantageous allele across
a barrier: the effects of random drift and selection against heterozygotes,” Genetics,
vol. 145, no. 2. Genetics Society of America, pp. 493–504, 1997.'
ista: 'Piálek J, Barton NH. 1997. The spread of an advantageous allele across a
barrier: the effects of random drift and selection against heterozygotes. Genetics.
145(2), 493–504.'
mla: 'Piálek, Jaroslav, and Nicholas H. Barton. “The Spread of an Advantageous Allele
across a Barrier: The Effects of Random Drift and Selection against Heterozygotes.”
Genetics, vol. 145, no. 2, Genetics Society of America, 1997, pp. 493–504,
doi:10.1093/genetics/145.2.493.'
short: J. Piálek, N.H. Barton, Genetics 145 (1997) 493–504.
date_created: 2018-12-11T12:08:03Z
date_published: 1997-02-01T00:00:00Z
date_updated: 2022-08-18T12:34:37Z
day: '01'
doi: 10.1093/genetics/145.2.493
extern: '1'
external_id:
pmid:
- '9071602'
intvolume: ' 145'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://academic.oup.com/genetics/article/145/2/493/6018085
month: '02'
oa: 1
oa_version: Published Version
page: 493 - 504
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '1797'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The spread of an advantageous allele across a barrier: the effects of random
drift and selection against heterozygotes'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 145
year: '1997'
...
---
_id: '4287'
abstract:
- lang: eng
text: 'We evaluate Sewall Wright''s three-phase "shifting balance" theory of evolution,
examining both the theoretical issues and the relevant data from nature and the
laboratory. We conclude that while phases I and II of Wright''s theory (the movement
of populations from one "adaptive peak" to another via drift and selection) can
occur under some conditions, genetic drift is often unnecessary for movement between
peaks. Phase III of the shifting balance, in which adaptations spread from particular
populations to the entire species, faces two major theoretical obstacles: (1)
unlike adaptations favored by simple directional selection, adaptations whose
fixation requires some genetic drift are often prevented from spreading by barriers
to gene flow; and (2) it is difficult to assemble complex adaptations whose constituent
parts arise via peak shifts in different demes. Our review of the data from nature
shows that although there is some evidence for individual phases of the shifting
balance process, there are few empirical observations explained better by Wright''s
three-phase mechanism than by simple mass selection. Similarly, artificial selection
experiments fail to show that selection in subdivided populations produces greater
response than does mass selection in large populations. The complexity of the
shifting balance process and the difficulty of establishing that adaptive valleys
have been crossed by genetic drift make it impossible to test Wright''s claim
that adaptations commonly originate by this process. In view of these problems,
it seems unreasonable to consider the shifting balance process as an important
explanation for the evolution of adaptations. '
acknowledgement: 'We thank the following people for discussion and comments on themanuscript:
S.Barrett,J. Bull, B.Charlesworth, D.Charlesworth, P. DeVries, S.Gavrilets, J. H.Gillespie,
R.K.Grosberg, W.G. Hill, A. A.Hoffmann, M.Kirkpatrick, C.H.Langley, R. C.Lewontin,
J.B. Mallet, M. Noor, L.Nunney, H. A. Orr, T. Prout, M.Slatkin, J.Spofford, W.Stephan,
J. B. Walsh, P. Ward, K. Weber, J. Willis, and M.Zwick. We are especially grateful
to D.J. Futuyma and D.Schemskefor their exhaustive criticism of the manuscript.
Needless to say, not all of these reviewers agree with our ideas. This work was
supported by National Institutes of Health grant GM50355 to JAC, National Science
Foundation grant DEB9527808 to MT, and grants from the Darwin Trust of Edinburgh
and the Biotechnology and Biological Sciences Research Council (GRJI76057,GRIHI09928)
to NHB.'
article_processing_charge: No
article_type: original
author:
- first_name: Jerry
full_name: Coyne, Jerry
last_name: Coyne
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Michael
full_name: Turelli, Michael
last_name: Turelli
citation:
ama: 'Coyne J, Barton NH, Turelli M. Perspective: A critique of Sewall Wright’s
shifting balance theory of evolutionight’s shifting balance theory of evolution.
Evolution; International Journal of Organic Evolution. 1997;51(3):643-671.
doi:10.1111/j.1558-5646.1997.tb03650.x'
apa: 'Coyne, J., Barton, N. H., & Turelli, M. (1997). Perspective: A critique
of Sewall Wright’s shifting balance theory of evolutionight’s shifting balance
theory of evolution. Evolution; International Journal of Organic Evolution.
Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.1997.tb03650.x'
chicago: 'Coyne, Jerry, Nicholas H Barton, and Michael Turelli. “Perspective: A
Critique of Sewall Wright’s Shifting Balance Theory of Evolutionight’s Shifting
Balance Theory of Evolution.” Evolution; International Journal of Organic Evolution.
Wiley-Blackwell, 1997. https://doi.org/10.1111/j.1558-5646.1997.tb03650.x.'
ieee: 'J. Coyne, N. H. Barton, and M. Turelli, “Perspective: A critique of Sewall
Wright’s shifting balance theory of evolutionight’s shifting balance theory of
evolution,” Evolution; International Journal of Organic Evolution, vol.
51, no. 3. Wiley-Blackwell, pp. 643–671, 1997.'
ista: 'Coyne J, Barton NH, Turelli M. 1997. Perspective: A critique of Sewall Wright’s
shifting balance theory of evolutionight’s shifting balance theory of evolution.
Evolution; International Journal of Organic Evolution. 51(3), 643–671.'
mla: 'Coyne, Jerry, et al. “Perspective: A Critique of Sewall Wright’s Shifting
Balance Theory of Evolutionight’s Shifting Balance Theory of Evolution.” Evolution;
International Journal of Organic Evolution, vol. 51, no. 3, Wiley-Blackwell,
1997, pp. 643–71, doi:10.1111/j.1558-5646.1997.tb03650.x.'
short: J. Coyne, N.H. Barton, M. Turelli, Evolution; International Journal of Organic
Evolution 51 (1997) 643–671.
date_created: 2018-12-11T12:08:03Z
date_published: 1997-06-01T00:00:00Z
date_updated: 2022-08-18T09:48:43Z
day: '01'
doi: 10.1111/j.1558-5646.1997.tb03650.x
extern: '1'
external_id:
pmid:
- '28568586'
intvolume: ' 51'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1558-5646.1997.tb03650.x
month: '06'
oa: 1
oa_version: Published Version
page: 643 - 671
pmid: 1
publication: Evolution; International Journal of Organic Evolution
publication_identifier:
issn:
- 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '1791'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Perspective: A critique of Sewall Wright''s shifting balance theory of evolutionight''s
shifting balance theory of evolution'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 51
year: '1997'
...
---
_id: '4288'
abstract:
- lang: eng
text: We measured the heterozygous effects on net fitness of a sample of 12 wild-type
third chromosomes in D. melanogaster. Effects on fitness were assessed by competing
the wild-type chromosomes against balancer chromosomes, to prevent the production
of recombinants. The measurements were carried out in the population cage environment
in which the life history had been evolving, in an undisturbed population with
overlapping generations, and replicated measurements were made on each chromosome
to control for confounding effects such as mutation accumulation. We found significant
variation among the wild type chromosomes in their additive genetic effect on
net fitness. The system provides an opportunity to obtain an accurate estimate
of the distribution of heterozygous effects on net fitness, the contribution of
different fitness components including male mating success, and the role of intra-chromosomal
epistasis in fitness variation.
acknowledgement: We thank John Sved for helpful discussions in the planningstages
of the project, Brian Charlesworth, Alexei Kondrashov, Trudy Mackay and Steve Stearns
for commentson the manuscript, SERC, BBSRC, the Darwin Trust andthe Royal Society
for Financial support, and Ms N. Goorneyfor technical assistance
article_processing_charge: No
article_type: original
author:
- first_name: Kevin
full_name: Fowler, Kevin
last_name: Fowler
- first_name: Colin
full_name: Semple, Colin
last_name: Semple
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Linda
full_name: Partridge, Linda
last_name: Partridge
citation:
ama: Fowler K, Semple C, Barton NH, Partridge L. Genetic variation for total fitness
in Drosophila melanogaster. Proceedings of the Royal Society of London Series
B Biological Sciences. 1997;264(1379):191-199. doi:10.1098/rspb.1997.0027
apa: Fowler, K., Semple, C., Barton, N. H., & Partridge, L. (1997). Genetic
variation for total fitness in Drosophila melanogaster. Proceedings of the
Royal Society of London Series B Biological Sciences. The Royal Society. https://doi.org/10.1098/rspb.1997.0027
chicago: Fowler, Kevin, Colin Semple, Nicholas H Barton, and Linda Partridge. “Genetic
Variation for Total Fitness in Drosophila Melanogaster.” Proceedings of the
Royal Society of London Series B Biological Sciences. The Royal Society, 1997.
https://doi.org/10.1098/rspb.1997.0027.
ieee: K. Fowler, C. Semple, N. H. Barton, and L. Partridge, “Genetic variation for
total fitness in Drosophila melanogaster,” Proceedings of the Royal Society
of London Series B Biological Sciences, vol. 264, no. 1379. The Royal Society,
pp. 191–199, 1997.
ista: Fowler K, Semple C, Barton NH, Partridge L. 1997. Genetic variation for total
fitness in Drosophila melanogaster. Proceedings of the Royal Society of London
Series B Biological Sciences. 264(1379), 191–199.
mla: Fowler, Kevin, et al. “Genetic Variation for Total Fitness in Drosophila Melanogaster.”
Proceedings of the Royal Society of London Series B Biological Sciences,
vol. 264, no. 1379, The Royal Society, 1997, pp. 191–99, doi:10.1098/rspb.1997.0027.
short: K. Fowler, C. Semple, N.H. Barton, L. Partridge, Proceedings of the Royal
Society of London Series B Biological Sciences 264 (1997) 191–199.
date_created: 2018-12-11T12:08:03Z
date_published: 1997-02-22T00:00:00Z
date_updated: 2022-08-18T11:31:58Z
day: '22'
doi: 10.1098/rspb.1997.0027
extern: '1'
external_id:
pmid:
- '9061969'
intvolume: ' 264'
issue: '1379'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1688253/
month: '02'
oa: 1
oa_version: Published Version
page: 191 - 199
pmid: 1
publication: Proceedings of the Royal Society of London Series B Biological Sciences
publication_identifier:
issn:
- 0962-8452
publication_status: published
publisher: The Royal Society
publist_id: '1792'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Genetic variation for total fitness in Drosophila melanogaster
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 264
year: '1997'
...
---
_id: '4289'
abstract:
- lang: eng
text: A worldwide survey of polymorphic molecular markers shows that the human population
is genetically homogeneous, in close agreement with evidence from quite different
genes and traits.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Barton NH. Population genetics: A new apportionment of human diversity. Current
Biology. 1997;7(12):757-758. doi:10.1016/S0960-9822(06)00397-6'
apa: 'Barton, N. H. (1997). Population genetics: A new apportionment of human diversity.
Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(06)00397-6'
chicago: 'Barton, Nicholas H. “Population Genetics: A New Apportionment of Human
Diversity.” Current Biology. Cell Press, 1997. https://doi.org/10.1016/S0960-9822(06)00397-6.'
ieee: 'N. H. Barton, “Population genetics: A new apportionment of human diversity,”
Current Biology, vol. 7, no. 12. Cell Press, pp. 757–758, 1997.'
ista: 'Barton NH. 1997. Population genetics: A new apportionment of human diversity.
Current Biology. 7(12), 757–758.'
mla: 'Barton, Nicholas H. “Population Genetics: A New Apportionment of Human Diversity.”
Current Biology, vol. 7, no. 12, Cell Press, 1997, pp. 757–58, doi:10.1016/S0960-9822(06)00397-6.'
short: N.H. Barton, Current Biology 7 (1997) 757–758.
date_created: 2018-12-11T12:08:04Z
date_published: 1997-12-01T00:00:00Z
date_updated: 2022-08-17T13:07:08Z
day: '01'
doi: 10.1016/S0960-9822(06)00397-6
extern: '1'
intvolume: ' 7'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.sciencedirect.com/science/article/pii/S0960982206003976?via%3Dihub
month: '12'
oa: 1
oa_version: Published Version
page: 757 - 758
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1788'
quality_controlled: '1'
status: public
title: 'Population genetics: A new apportionment of human diversity'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 7
year: '1997'
...
---
_id: '4290'
article_processing_charge: No
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. Natural hybridization and evolution. Genetical Research.
1997;70(2):178-180.
apa: Barton, N. H. (1997). Natural hybridization and evolution. Genetical Research.
Cambridge University Press.
chicago: Barton, Nicholas H. “Natural Hybridization and Evolution.” Genetical
Research. Cambridge University Press, 1997.
ieee: N. H. Barton, “Natural hybridization and evolution,” Genetical Research,
vol. 70, no. 2. Cambridge University Press, pp. 178–180, 1997.
ista: Barton NH. 1997. Natural hybridization and evolution. Genetical Research.
70(2), 178–180.
mla: Barton, Nicholas H. “Natural Hybridization and Evolution.” Genetical Research,
vol. 70, no. 2, Cambridge University Press, 1997, pp. 178–80.
short: N.H. Barton, Genetical Research 70 (1997) 178–180.
date_created: 2018-12-11T12:08:04Z
date_published: 1997-10-01T00:00:00Z
date_updated: 2022-08-17T14:10:20Z
day: '01'
extern: '1'
intvolume: ' 70'
issue: '2'
language:
- iso: eng
month: '10'
oa_version: None
page: 178 - 180
publication: Genetical Research
publication_identifier:
issn:
- 0016-6723
publication_status: published
publisher: Cambridge University Press
publist_id: '1789'
status: public
title: Natural hybridization and evolution
type: review
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 70
year: '1997'
...