---
_id: '14655'
abstract:
- lang: eng
  text: The kinetics of the assembly of semiflexible filaments through end-to-end
    annealing is key to the structure of the cytoskeleton, but is not understood.
    We analyze this problem through scaling theory and simulations, and uncover a
    regime where filaments’ ends find each other through bending fluctuations without
    the need for the whole filament to diffuse. This results in a very substantial
    speedup of assembly in physiological regimes, and could help with understanding
    the dynamics of actin and intermediate filaments in biological processes such
    as wound healing and cell division.
acknowledgement: The authors thank C´ecile Leduc and Duc-Quang Tran for invaluable
  help with understanding the experimental behavior of intermediate filaments, and
  Raphael Voituriez, Nicolas Levernier, and Alexander Grosberg for fruitful discussion
  on the theoretical model. V. S. also thanks Davide Michieletto, Maria Panoukidou,
  and Lorenzo Rovigatti for very helpful suggestions on the simulation model. M. L.
  was supported by Marie Curie Integration Grant No. PCIG12-GA-2012-334053, “Investissements
  d’Avenir” LabEx PALM (ANR-10-LABX- 0039-PALM), ANR Grants No. ANR-15-CE13-0004-03,
  No. ANR-21-CE11-0004-02 and No. ANR-22-CE30-0024, as well as ERC Starting Grant
  No. 677532. M.L.’s group belongs to the CNRS consortium AQV. Part of this work was
  performed using HPC resources from GENCI–IDRIS (Grants No. 2020-A0090712066 and
  No. 2021-A0110712066).
article_number: '228401'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Valerio
  full_name: Sorichetti, Valerio
  id: ef8a92cb-c7b6-11ec-8bea-e1fd5847bc5b
  last_name: Sorichetti
  orcid: 0000-0002-9645-6576
- first_name: Martin
  full_name: Lenz, Martin
  last_name: Lenz
citation:
  ama: Sorichetti V, Lenz M. Transverse fluctuations control the assembly of semiflexible
    filaments. <i>Physical Review Letters</i>. 2023;131(22). doi:<a href="https://doi.org/10.1103/PhysRevLett.131.228401">10.1103/PhysRevLett.131.228401</a>
  apa: Sorichetti, V., &#38; Lenz, M. (2023). Transverse fluctuations control the
    assembly of semiflexible filaments. <i>Physical Review Letters</i>. American Physical
    Society. <a href="https://doi.org/10.1103/PhysRevLett.131.228401">https://doi.org/10.1103/PhysRevLett.131.228401</a>
  chicago: Sorichetti, Valerio, and Martin Lenz. “Transverse Fluctuations Control
    the Assembly of Semiflexible Filaments.” <i>Physical Review Letters</i>. American
    Physical Society, 2023. <a href="https://doi.org/10.1103/PhysRevLett.131.228401">https://doi.org/10.1103/PhysRevLett.131.228401</a>.
  ieee: V. Sorichetti and M. Lenz, “Transverse fluctuations control the assembly of
    semiflexible filaments,” <i>Physical Review Letters</i>, vol. 131, no. 22. American
    Physical Society, 2023.
  ista: Sorichetti V, Lenz M. 2023. Transverse fluctuations control the assembly of
    semiflexible filaments. Physical Review Letters. 131(22), 228401.
  mla: Sorichetti, Valerio, and Martin Lenz. “Transverse Fluctuations Control the
    Assembly of Semiflexible Filaments.” <i>Physical Review Letters</i>, vol. 131,
    no. 22, 228401, American Physical Society, 2023, doi:<a href="https://doi.org/10.1103/PhysRevLett.131.228401">10.1103/PhysRevLett.131.228401</a>.
  short: V. Sorichetti, M. Lenz, Physical Review Letters 131 (2023).
date_created: 2023-12-10T23:00:57Z
date_published: 2023-12-01T00:00:00Z
date_updated: 2023-12-11T07:59:25Z
day: '01'
department:
- _id: AnSa
doi: 10.1103/PhysRevLett.131.228401
external_id:
  arxiv:
  - '2303.03088'
intvolume: '       131'
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2303.03088
month: '12'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transverse fluctuations control the assembly of semiflexible filaments
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 131
year: '2023'
...
---
_id: '12705'
abstract:
- lang: eng
  text: The elasticity of disordered and polydisperse polymer networks is a fundamental
    problem of soft matter physics that is still open. Here, we self-assemble polymer
    networks via simulations of a mixture of bivalent and tri- or tetravalent patchy
    particles, which result in an exponential strand length distribution analogous
    to that of experimental randomly cross-linked systems. After assembly, the network
    connectivity and topology are frozen and the resulting system is characterized.
    We find that the fractal structure of the network depends on the number density
    at which the assembly has been carried out, but that systems with the same mean
    valence and same assembly density have the same structural properties. Moreover,
    we compute the long-time limit of the mean-squared displacement, also known as
    the (squared) localization length, of the cross-links and of the middle monomers
    of the strands, showing that the dynamics of long strands is well described by
    the tube model. Finally, we find a relation connecting these two localization
    lengths at high density and connect the cross-link localization length to the
    shear modulus of the system.
acknowledgement: We thank Michael Lang for helpful discussions. We acknowledge financial
  support from the European Research Council (ERC Consolidator Grant No. 681597, MIMIC)
  and from LabEx NUMEV (Grant No. ANR-10-LABX-20) funded by the “Investissements d’Avenir”
  French Government program, managed by the French National Research Agency (ANR).
  W.K. is a senior member of the Institut Universitaire de France.
article_number: '074905'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Valerio
  full_name: Sorichetti, Valerio
  id: ef8a92cb-c7b6-11ec-8bea-e1fd5847bc5b
  last_name: Sorichetti
  orcid: 0000-0002-9645-6576
- first_name: Andrea
  full_name: Ninarello, Andrea
  last_name: Ninarello
- first_name: José
  full_name: Ruiz-Franco, José
  last_name: Ruiz-Franco
- first_name: Virginie
  full_name: Hugouvieux, Virginie
  last_name: Hugouvieux
- first_name: Emanuela
  full_name: Zaccarelli, Emanuela
  last_name: Zaccarelli
- first_name: Cristian
  full_name: Micheletti, Cristian
  last_name: Micheletti
- first_name: Walter
  full_name: Kob, Walter
  last_name: Kob
- first_name: Lorenzo
  full_name: Rovigatti, Lorenzo
  last_name: Rovigatti
citation:
  ama: Sorichetti V, Ninarello A, Ruiz-Franco J, et al. Structure and elasticity of
    model disordered, polydisperse, and defect-free polymer networks. <i>Journal of
    Chemical Physics</i>. 2023;158(7). doi:<a href="https://doi.org/10.1063/5.0134271">10.1063/5.0134271</a>
  apa: Sorichetti, V., Ninarello, A., Ruiz-Franco, J., Hugouvieux, V., Zaccarelli,
    E., Micheletti, C., … Rovigatti, L. (2023). Structure and elasticity of model
    disordered, polydisperse, and defect-free polymer networks. <i>Journal of Chemical
    Physics</i>. American Institute of Physics. <a href="https://doi.org/10.1063/5.0134271">https://doi.org/10.1063/5.0134271</a>
  chicago: Sorichetti, Valerio, Andrea Ninarello, José Ruiz-Franco, Virginie Hugouvieux,
    Emanuela Zaccarelli, Cristian Micheletti, Walter Kob, and Lorenzo Rovigatti. “Structure
    and Elasticity of Model Disordered, Polydisperse, and Defect-Free Polymer Networks.”
    <i>Journal of Chemical Physics</i>. American Institute of Physics, 2023. <a href="https://doi.org/10.1063/5.0134271">https://doi.org/10.1063/5.0134271</a>.
  ieee: V. Sorichetti <i>et al.</i>, “Structure and elasticity of model disordered,
    polydisperse, and defect-free polymer networks,” <i>Journal of Chemical Physics</i>,
    vol. 158, no. 7. American Institute of Physics, 2023.
  ista: Sorichetti V, Ninarello A, Ruiz-Franco J, Hugouvieux V, Zaccarelli E, Micheletti
    C, Kob W, Rovigatti L. 2023. Structure and elasticity of model disordered, polydisperse,
    and defect-free polymer networks. Journal of Chemical Physics. 158(7), 074905.
  mla: Sorichetti, Valerio, et al. “Structure and Elasticity of Model Disordered,
    Polydisperse, and Defect-Free Polymer Networks.” <i>Journal of Chemical Physics</i>,
    vol. 158, no. 7, 074905, American Institute of Physics, 2023, doi:<a href="https://doi.org/10.1063/5.0134271">10.1063/5.0134271</a>.
  short: V. Sorichetti, A. Ninarello, J. Ruiz-Franco, V. Hugouvieux, E. Zaccarelli,
    C. Micheletti, W. Kob, L. Rovigatti, Journal of Chemical Physics 158 (2023).
date_created: 2023-03-05T23:01:05Z
date_published: 2023-02-21T00:00:00Z
date_updated: 2023-10-03T11:31:51Z
day: '21'
department:
- _id: AnSa
doi: 10.1063/5.0134271
external_id:
  arxiv:
  - '2211.04810'
  isi:
  - '000936943800002'
  pmid:
  - '36813705'
intvolume: '       158'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2211.04810
month: '02'
oa: 1
oa_version: Preprint
pmid: 1
publication: Journal of Chemical Physics
publication_identifier:
  eissn:
  - 1089-7690
  issn:
  - 0021-9606
publication_status: published
publisher: American Institute of Physics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structure and elasticity of model disordered, polydisperse, and defect-free
  polymer networks
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 158
year: '2023'
...