[{"date_created":"2024-01-08T13:16:36Z","title":"Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression","abstract":[{"text":"The cerebral cortex is comprised of a vast cell-type diversity sequentially generated by cortical progenitor cells. Faithful progenitor lineage progression requires the tight orchestration of distinct molecular and cellular mechanisms regulating proper progenitor proliferation behavior and differentiation. Correct execution of developmental programs involves a complex interplay of cell intrinsic and tissue-wide mechanisms. Many studies over the past decades have been able to determine a plethora of genes critically involved in cortical development. However, only a few made use of genetic paradigms with sparse and global gene deletion to probe cell-autonomous vs. tissue-wide contribution. In this chapter, we will elaborate on the importance of dissecting the cell-autonomous and tissue-wide mechanisms to gain a precise understanding of gene function during radial glial progenitor lineage progression.","lang":"eng"}],"day":"08","date_updated":"2024-01-09T09:46:57Z","oa_version":"None","month":"08","type":"book_chapter","page":"169-191","author":[{"full_name":"Villalba Requena, Ana","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","orcid":"0000-0002-5615-5277","last_name":"Villalba Requena","first_name":"Ana"},{"last_name":"Amberg","first_name":"Nicole","full_name":"Amberg, Nicole","id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-3183-8207"},{"full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","last_name":"Hippenmeyer"}],"scopus_import":"1","article_processing_charge":"No","publication":"Neocortical Neurogenesis in Development and Evolution","_id":"14757","department":[{"_id":"SiHi"}],"year":"2023","publisher":"Wiley","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","doi":"10.1002/9781119860914.ch10","date_published":"2023-08-08T00:00:00Z","publication_status":"published","publication_identifier":{"eisbn":["9781119860914"]},"language":[{"iso":"eng"}],"citation":{"mla":"Villalba Requena, Ana, et al. “Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression.” <i>Neocortical Neurogenesis in Development and Evolution</i>, edited by Wieland Huttner, Wiley, 2023, pp. 169–91, doi:<a href=\"https://doi.org/10.1002/9781119860914.ch10\">10.1002/9781119860914.ch10</a>.","ista":"Villalba Requena A, Amberg N, Hippenmeyer S. 2023.Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression. In: Neocortical Neurogenesis in Development and Evolution. , 169–191.","apa":"Villalba Requena, A., Amberg, N., &#38; Hippenmeyer, S. (2023). Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression. In W. Huttner (Ed.), <i>Neocortical Neurogenesis in Development and Evolution</i> (pp. 169–191). Wiley. <a href=\"https://doi.org/10.1002/9781119860914.ch10\">https://doi.org/10.1002/9781119860914.ch10</a>","ama":"Villalba Requena A, Amberg N, Hippenmeyer S. Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression. In: Huttner W, ed. <i>Neocortical Neurogenesis in Development and Evolution</i>. Wiley; 2023:169-191. doi:<a href=\"https://doi.org/10.1002/9781119860914.ch10\">10.1002/9781119860914.ch10</a>","short":"A. Villalba Requena, N. Amberg, S. Hippenmeyer, in:, W. Huttner (Ed.), Neocortical Neurogenesis in Development and Evolution, Wiley, 2023, pp. 169–191.","ieee":"A. Villalba Requena, N. Amberg, and S. Hippenmeyer, “Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression,” in <i>Neocortical Neurogenesis in Development and Evolution</i>, W. Huttner, Ed. Wiley, 2023, pp. 169–191.","chicago":"Villalba Requena, Ana, Nicole Amberg, and Simon Hippenmeyer. “Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression.” In <i>Neocortical Neurogenesis in Development and Evolution</i>, edited by Wieland Huttner, 169–91. Wiley, 2023. <a href=\"https://doi.org/10.1002/9781119860914.ch10\">https://doi.org/10.1002/9781119860914.ch10</a>."},"editor":[{"first_name":"Wieland","last_name":"Huttner","full_name":"Huttner, Wieland"}],"status":"public"},{"language":[{"iso":"eng"}],"issue":"3","isi":1,"quality_controlled":"1","doi":"10.1016/j.neuron.2023.01.006","publication_identifier":{"eissn":["1097-4199"]},"scopus_import":"1","article_processing_charge":"No","article_type":"letter_note","publication":"Neuron","department":[{"_id":"SiHi"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publisher":"Elsevier","title":"Going back in time with TEMPO","day":"01","author":[{"first_name":"Ana","last_name":"Villalba Requena","orcid":"0000-0002-5615-5277","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","full_name":"Villalba Requena, Ana"},{"orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon","last_name":"Hippenmeyer","first_name":"Simon"}],"citation":{"chicago":"Villalba Requena, Ana, and Simon Hippenmeyer. “Going Back in Time with TEMPO.” <i>Neuron</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.neuron.2023.01.006\">https://doi.org/10.1016/j.neuron.2023.01.006</a>.","ieee":"A. Villalba Requena and S. Hippenmeyer, “Going back in time with TEMPO,” <i>Neuron</i>, vol. 111, no. 3. Elsevier, pp. 291–293, 2023.","short":"A. Villalba Requena, S. Hippenmeyer, Neuron 111 (2023) 291–293.","ama":"Villalba Requena A, Hippenmeyer S. Going back in time with TEMPO. <i>Neuron</i>. 2023;111(3):291-293. doi:<a href=\"https://doi.org/10.1016/j.neuron.2023.01.006\">10.1016/j.neuron.2023.01.006</a>","apa":"Villalba Requena, A., &#38; Hippenmeyer, S. (2023). Going back in time with TEMPO. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2023.01.006\">https://doi.org/10.1016/j.neuron.2023.01.006</a>","mla":"Villalba Requena, Ana, and Simon Hippenmeyer. “Going Back in Time with TEMPO.” <i>Neuron</i>, vol. 111, no. 3, Elsevier, 2023, pp. 291–93, doi:<a href=\"https://doi.org/10.1016/j.neuron.2023.01.006\">10.1016/j.neuron.2023.01.006</a>.","ista":"Villalba Requena A, Hippenmeyer S. 2023. Going back in time with TEMPO. Neuron. 111(3), 291–293."},"intvolume":"       111","external_id":{"isi":["000994473300001"]},"status":"public","date_published":"2023-02-01T00:00:00Z","publication_status":"published","_id":"12542","year":"2023","date_created":"2023-02-12T23:00:58Z","volume":111,"date_updated":"2023-08-01T13:10:27Z","abstract":[{"lang":"eng","text":"In this issue of Neuron, Espinosa-Medina et al.1 present the TEMPO (Temporal Encoding and Manipulation in a Predefined Order) system, which enables the marking and genetic manipulation of sequentially generated cell lineages in vertebrate species in vivo."}],"type":"journal_article","oa_version":"None","month":"02","page":"291-293"}]