---
_id: '10284'
abstract:
- lang: eng
text: Infections early in life can have enduring effects on an organism's development
and immunity. In this study, we show that this equally applies to developing ‘superorganisms’––incipient
social insect colonies. When we exposed newly mated Lasius niger ant queens to
a low pathogen dose, their colonies grew more slowly than controls before winter,
but reached similar sizes afterwards. Independent of exposure, queen hibernation
survival improved when the ratio of pupae to workers was small. Queens that reared
fewer pupae before worker emergence exhibited lower pathogen levels, indicating
that high brood rearing efforts interfere with the ability of the queen's immune
system to suppress pathogen proliferation. Early-life queen pathogen exposure
also improved the immunocompetence of her worker offspring, as demonstrated by
challenging the workers to the same pathogen a year later. Transgenerational transfer
of the queen's pathogen experience to her workforce can hence durably reduce the
disease susceptibility of the whole superorganism.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: The authors are grateful to G. Tkačik and V. Mireles for advice on
data analyses and to A. Schloegl for help using the IST Austria HPC cluster for
data processing. The authors thank J. Eilenberg for providing the fungal strain
and A.V. Grasse for support with the molecular analysis. The authors also thank
the Social Immunity group at IST Austria, in particular B. Milutinović, for discussions
throughout and comments on the manuscript.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Barbara E
full_name: Casillas Perez, Barbara E
id: 351ED2AA-F248-11E8-B48F-1D18A9856A87
last_name: Casillas Perez
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Filip
full_name: Naiser, Filip
last_name: Naiser
- first_name: Elisabeth
full_name: Naderlinger, Elisabeth
id: 31757262-F248-11E8-B48F-1D18A9856A87
last_name: Naderlinger
- first_name: Jiri
full_name: Matas, Jiri
last_name: Matas
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Casillas Perez BE, Pull C, Naiser F, Naderlinger E, Matas J, Cremer S. Early
queen infection shapes developmental dynamics and induces long-term disease protection
in incipient ant colonies. Ecology Letters. 2022;25(1):89-100. doi:10.1111/ele.13907
apa: Casillas Perez, B. E., Pull, C., Naiser, F., Naderlinger, E., Matas, J., &
Cremer, S. (2022). Early queen infection shapes developmental dynamics and induces
long-term disease protection in incipient ant colonies. Ecology Letters.
Wiley. https://doi.org/10.1111/ele.13907
chicago: Casillas Perez, Barbara E, Christopher Pull, Filip Naiser, Elisabeth Naderlinger,
Jiri Matas, and Sylvia Cremer. “Early Queen Infection Shapes Developmental Dynamics
and Induces Long-Term Disease Protection in Incipient Ant Colonies.” Ecology
Letters. Wiley, 2022. https://doi.org/10.1111/ele.13907.
ieee: B. E. Casillas Perez, C. Pull, F. Naiser, E. Naderlinger, J. Matas, and S.
Cremer, “Early queen infection shapes developmental dynamics and induces long-term
disease protection in incipient ant colonies,” Ecology Letters, vol. 25,
no. 1. Wiley, pp. 89–100, 2022.
ista: Casillas Perez BE, Pull C, Naiser F, Naderlinger E, Matas J, Cremer S. 2022.
Early queen infection shapes developmental dynamics and induces long-term disease
protection in incipient ant colonies. Ecology Letters. 25(1), 89–100.
mla: Casillas Perez, Barbara E., et al. “Early Queen Infection Shapes Developmental
Dynamics and Induces Long-Term Disease Protection in Incipient Ant Colonies.”
Ecology Letters, vol. 25, no. 1, Wiley, 2022, pp. 89–100, doi:10.1111/ele.13907.
short: B.E. Casillas Perez, C. Pull, F. Naiser, E. Naderlinger, J. Matas, S. Cremer,
Ecology Letters 25 (2022) 89–100.
date_created: 2021-11-14T23:01:25Z
date_published: 2022-01-01T00:00:00Z
date_updated: 2023-08-14T11:45:29Z
day: '01'
ddc:
- '573'
department:
- _id: SyCr
doi: 10.1111/ele.13907
ec_funded: 1
external_id:
isi:
- '000713396100001'
pmid:
- '34725912'
file:
- access_level: open_access
checksum: 0bd4210400e9876609b7c538ab4f9a3c
content_type: application/pdf
creator: cchlebak
date_created: 2022-02-03T13:37:11Z
date_updated: 2022-02-03T13:37:11Z
file_id: '10721'
file_name: 2021_EcologyLetters_CasillasPerez.pdf
file_size: 700087
relation: main_file
success: 1
file_date_updated: 2022-02-03T13:37:11Z
has_accepted_license: '1'
intvolume: ' 25'
isi: 1
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language:
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month: '01'
oa: 1
oa_version: Published Version
page: 89-100
pmid: 1
project:
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call_identifier: H2020
grant_number: '771402'
name: Epidemics in ant societies on a chip
publication: Ecology Letters
publication_identifier:
eissn:
- 1461-0248
issn:
- 1461-023X
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
record:
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relation: research_data
status: public
scopus_import: '1'
status: public
title: Early queen infection shapes developmental dynamics and induces long-term disease
protection in incipient ant colonies
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 25
year: '2022'
...
---
_id: '13061'
abstract:
- lang: eng
text: Infections early in life can have enduring effects on an organism’s development
and immunity. In this study, we show that this equally applies to developing “superorganisms”
– incipient social insect colonies. When we exposed newly mated Lasius niger ant
queens to a low pathogen dose, their colonies grew more slowly than controls before
winter, but reached similar sizes afterwards. Independent of exposure, queen hibernation
survival improved when the ratio of pupae to workers was small. Queens that reared
fewer pupae before worker emergence exhibited lower pathogen levels, indicating
that high brood rearing efforts interfere with the ability of the queen’s immune
system to suppress pathogen proliferation. Early-life queen pathogen-exposure
also improved the immunocompetence of her worker offspring, as demonstrated by
challenging the workers to the same pathogen a year later. Transgenerational transfer
of the queen’s pathogen experience to her workforce can hence durably reduce the
disease susceptibility of the whole superorganism.
article_processing_charge: No
author:
- first_name: Barbara E
full_name: Casillas Perez, Barbara E
id: 351ED2AA-F248-11E8-B48F-1D18A9856A87
last_name: Casillas Perez
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Filip
full_name: Naiser, Filip
last_name: Naiser
- first_name: Elisabeth
full_name: Naderlinger, Elisabeth
last_name: Naderlinger
- first_name: Jiri
full_name: Matas, Jiri
last_name: Matas
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Casillas Perez BE, Pull C, Naiser F, Naderlinger E, Matas J, Cremer S. Early
queen infection shapes developmental dynamics and induces long-term disease protection
in incipient ant colonies. 2021. doi:10.5061/DRYAD.7PVMCVDTJ
apa: Casillas Perez, B. E., Pull, C., Naiser, F., Naderlinger, E., Matas, J., &
Cremer, S. (2021). Early queen infection shapes developmental dynamics and induces
long-term disease protection in incipient ant colonies. Dryad. https://doi.org/10.5061/DRYAD.7PVMCVDTJ
chicago: Casillas Perez, Barbara E, Christopher Pull, Filip Naiser, Elisabeth Naderlinger,
Jiri Matas, and Sylvia Cremer. “Early Queen Infection Shapes Developmental Dynamics
and Induces Long-Term Disease Protection in Incipient Ant Colonies.” Dryad, 2021.
https://doi.org/10.5061/DRYAD.7PVMCVDTJ.
ieee: B. E. Casillas Perez, C. Pull, F. Naiser, E. Naderlinger, J. Matas, and S.
Cremer, “Early queen infection shapes developmental dynamics and induces long-term
disease protection in incipient ant colonies.” Dryad, 2021.
ista: Casillas Perez BE, Pull C, Naiser F, Naderlinger E, Matas J, Cremer S. 2021.
Early queen infection shapes developmental dynamics and induces long-term disease
protection in incipient ant colonies, Dryad, 10.5061/DRYAD.7PVMCVDTJ.
mla: Casillas Perez, Barbara E., et al. Early Queen Infection Shapes Developmental
Dynamics and Induces Long-Term Disease Protection in Incipient Ant Colonies.
Dryad, 2021, doi:10.5061/DRYAD.7PVMCVDTJ.
short: B.E. Casillas Perez, C. Pull, F. Naiser, E. Naderlinger, J. Matas, S. Cremer,
(2021).
date_created: 2023-05-23T16:14:35Z
date_published: 2021-10-29T00:00:00Z
date_updated: 2023-08-14T11:45:28Z
day: '29'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.5061/DRYAD.7PVMCVDTJ
ec_funded: 1
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.7pvmcvdtj
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 2649B4DE-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '771402'
name: Epidemics in ant societies on a chip
publisher: Dryad
related_material:
record:
- id: '10284'
relation: used_in_publication
status: public
status: public
title: Early queen infection shapes developmental dynamics and induces long-term disease
protection in incipient ant colonies
tmp:
image: /images/cc_0.png
legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
name: Creative Commons Public Domain Dedication (CC0 1.0)
short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '806'
abstract:
- lang: eng
text: Social insect colonies have evolved many collectively performed adaptations
that reduce the impact of infectious disease and that are expected to maximize
their fitness. This colony-level protection is termed social immunity, and it
enhances the health and survival of the colony. In this review, we address how
social immunity emerges from its mechanistic components to produce colony-level
disease avoidance, resistance, and tolerance. To understand the evolutionary causes
and consequences of social immunity, we highlight the need for studies that evaluate
the effects of social immunity on colony fitness. We discuss the role that host
life history and ecology have on predicted eco-evolutionary dynamics, which differ
among the social insect lineages. Throughout the review, we highlight current
gaps in our knowledge and promising avenues for future research, which we hope
will bring us closer to an integrated understanding of socio-eco-evo-immunology.
article_processing_charge: No
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Matthias
full_name: Fürst, Matthias
id: 393B1196-F248-11E8-B48F-1D18A9856A87
last_name: Fürst
orcid: 0000-0002-3712-925X
citation:
ama: 'Cremer S, Pull C, Fürst M. Social immunity: Emergence and evolution of colony-level
disease protection. Annual Review of Entomology. 2018;63:105-123. doi:10.1146/annurev-ento-020117-043110'
apa: 'Cremer, S., Pull, C., & Fürst, M. (2018). Social immunity: Emergence and
evolution of colony-level disease protection. Annual Review of Entomology.
Annual Reviews. https://doi.org/10.1146/annurev-ento-020117-043110'
chicago: 'Cremer, Sylvia, Christopher Pull, and Matthias Fürst. “Social Immunity:
Emergence and Evolution of Colony-Level Disease Protection.” Annual Review
of Entomology. Annual Reviews, 2018. https://doi.org/10.1146/annurev-ento-020117-043110.'
ieee: 'S. Cremer, C. Pull, and M. Fürst, “Social immunity: Emergence and evolution
of colony-level disease protection,” Annual Review of Entomology, vol.
63. Annual Reviews, pp. 105–123, 2018.'
ista: 'Cremer S, Pull C, Fürst M. 2018. Social immunity: Emergence and evolution
of colony-level disease protection. Annual Review of Entomology. 63, 105–123.'
mla: 'Cremer, Sylvia, et al. “Social Immunity: Emergence and Evolution of Colony-Level
Disease Protection.” Annual Review of Entomology, vol. 63, Annual Reviews,
2018, pp. 105–23, doi:10.1146/annurev-ento-020117-043110.'
short: S. Cremer, C. Pull, M. Fürst, Annual Review of Entomology 63 (2018) 105–123.
date_created: 2018-12-11T11:48:36Z
date_published: 2018-01-07T00:00:00Z
date_updated: 2023-09-19T09:29:45Z
day: '07'
department:
- _id: SyCr
doi: 10.1146/annurev-ento-020117-043110
external_id:
isi:
- '000424633700008'
intvolume: ' 63'
isi: 1
language:
- iso: eng
month: '01'
oa_version: None
page: 105 - 123
publication: Annual Review of Entomology
publication_identifier:
issn:
- 1545-4487
publication_status: published
publisher: Annual Reviews
publist_id: '6844'
quality_controlled: '1'
related_material:
record:
- id: '819'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: 'Social immunity: Emergence and evolution of colony-level disease protection'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 63
year: '2018'
...
---
_id: '55'
abstract:
- lang: eng
text: Many animals use antimicrobials to prevent or cure disease [1,2]. For example,
some animals will ingest plants with medicinal properties, both prophylactically
to prevent infection and therapeutically to self-medicate when sick. Antimicrobial
substances are also used as topical disinfectants, to prevent infection, protect
offspring and to sanitise their surroundings [1,2]. Social insects (ants, bees,
wasps and termites) build nests in environments with a high abundance and diversity
of pathogenic microorganisms — such as soil and rotting wood — and colonies are
often densely crowded, creating conditions that favour disease outbreaks. Consequently,
social insects have evolved collective disease defences to protect their colonies
from epidemics. These traits can be seen as functionally analogous to the immune
system of individual organisms [3,4]. This ‘social immunity’ utilises antimicrobials
to prevent and eradicate infections, and to keep the brood and nest clean. However,
these antimicrobial compounds can be harmful to the insects themselves, and it
is unknown how colonies prevent collateral damage when using them. Here, we demonstrate
that antimicrobial acids, produced by workers to disinfect the colony, are harmful
to the delicate pupal brood stage, but that the pupae are protected from the acids
by the presence of a silk cocoon. Garden ants spray their nests with an antimicrobial
poison to sanitize contaminated nestmates and brood. Here, Pull et al show that
they also prophylactically sanitise their colonies, and that the silk cocoon serves
as a barrier to protect developing pupae, thus preventing collateral damage during
nest sanitation.
article_processing_charge: No
article_type: original
author:
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Sina
full_name: Metzler, Sina
id: 48204546-F248-11E8-B48F-1D18A9856A87
last_name: Metzler
orcid: 0000-0002-9547-2494
- first_name: Elisabeth
full_name: Naderlinger, Elisabeth
id: 31757262-F248-11E8-B48F-1D18A9856A87
last_name: Naderlinger
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Pull C, Metzler S, Naderlinger E, Cremer S. Protection against the lethal side
effects of social immunity in ants. Current Biology. 2018;28(19):R1139-R1140.
doi:10.1016/j.cub.2018.08.063
apa: Pull, C., Metzler, S., Naderlinger, E., & Cremer, S. (2018). Protection
against the lethal side effects of social immunity in ants. Current Biology.
Cell Press. https://doi.org/10.1016/j.cub.2018.08.063
chicago: Pull, Christopher, Sina Metzler, Elisabeth Naderlinger, and Sylvia Cremer.
“Protection against the Lethal Side Effects of Social Immunity in Ants.” Current
Biology. Cell Press, 2018. https://doi.org/10.1016/j.cub.2018.08.063.
ieee: C. Pull, S. Metzler, E. Naderlinger, and S. Cremer, “Protection against the
lethal side effects of social immunity in ants,” Current Biology, vol.
28, no. 19. Cell Press, pp. R1139–R1140, 2018.
ista: Pull C, Metzler S, Naderlinger E, Cremer S. 2018. Protection against the lethal
side effects of social immunity in ants. Current Biology. 28(19), R1139–R1140.
mla: Pull, Christopher, et al. “Protection against the Lethal Side Effects of Social
Immunity in Ants.” Current Biology, vol. 28, no. 19, Cell Press, 2018,
pp. R1139–40, doi:10.1016/j.cub.2018.08.063.
short: C. Pull, S. Metzler, E. Naderlinger, S. Cremer, Current Biology 28 (2018)
R1139–R1140.
date_created: 2018-12-11T11:44:23Z
date_published: 2018-10-08T00:00:00Z
date_updated: 2023-09-15T12:06:46Z
day: '08'
department:
- _id: SyCr
doi: 10.1016/j.cub.2018.08.063
external_id:
isi:
- '000446693400008'
intvolume: ' 28'
isi: 1
issue: '19'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cub.2018.08.063
month: '10'
oa: 1
oa_version: Published Version
page: R1139 - R1140
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '7999'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Protection against the lethal side effects of social immunity in ants
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 28
year: '2018'
...
---
_id: '616'
abstract:
- lang: eng
text: Social insects protect their colonies from infectious disease through collective
defences that result in social immunity. In ants, workers first try to prevent
infection of colony members. Here, we show that if this fails and a pathogen establishes
an infection, ants employ an efficient multicomponent behaviour − "destructive
disinfection" − to prevent further spread of disease through the colony.
Ants specifically target infected pupae during the pathogen's non-contagious incubation
period, relying on chemical 'sickness cues' emitted by pupae. They then remove
the pupal cocoon, perforate its cuticle and administer antimicrobial poison, which
enters the body and prevents pathogen replication from the inside out. Like the
immune system of a body that specifically targets and eliminates infected cells,
this social immunity measure sacrifices infected brood to stop the pathogen completing
its lifecycle, thus protecting the rest of the colony. Hence, the same principles
of disease defence apply at different levels of biological organisation.
article_number: e32073
article_processing_charge: Yes
author:
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Line V
full_name: Ugelvig, Line V
id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
last_name: Ugelvig
orcid: 0000-0003-1832-8883
- first_name: Florian
full_name: Wiesenhofer, Florian
id: 39523C54-F248-11E8-B48F-1D18A9856A87
last_name: Wiesenhofer
- first_name: Anna V
full_name: Grasse, Anna V
id: 406F989C-F248-11E8-B48F-1D18A9856A87
last_name: Grasse
- first_name: Simon
full_name: Tragust, Simon
id: 35A7A418-F248-11E8-B48F-1D18A9856A87
last_name: Tragust
- first_name: Thomas
full_name: Schmitt, Thomas
last_name: Schmitt
- first_name: Mark
full_name: Brown, Mark
last_name: Brown
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Pull C, Ugelvig LV, Wiesenhofer F, et al. Destructive disinfection of infected
brood prevents systemic disease spread in ant colonies. eLife. 2018;7.
doi:10.7554/eLife.32073
apa: Pull, C., Ugelvig, L. V., Wiesenhofer, F., Grasse, A. V., Tragust, S., Schmitt,
T., … Cremer, S. (2018). Destructive disinfection of infected brood prevents systemic
disease spread in ant colonies. ELife. eLife Sciences Publications. https://doi.org/10.7554/eLife.32073
chicago: Pull, Christopher, Line V Ugelvig, Florian Wiesenhofer, Anna V Grasse,
Simon Tragust, Thomas Schmitt, Mark Brown, and Sylvia Cremer. “Destructive Disinfection
of Infected Brood Prevents Systemic Disease Spread in Ant Colonies.” ELife.
eLife Sciences Publications, 2018. https://doi.org/10.7554/eLife.32073.
ieee: C. Pull et al., “Destructive disinfection of infected brood prevents
systemic disease spread in ant colonies,” eLife, vol. 7. eLife Sciences
Publications, 2018.
ista: Pull C, Ugelvig LV, Wiesenhofer F, Grasse AV, Tragust S, Schmitt T, Brown
M, Cremer S. 2018. Destructive disinfection of infected brood prevents systemic
disease spread in ant colonies. eLife. 7, e32073.
mla: Pull, Christopher, et al. “Destructive Disinfection of Infected Brood Prevents
Systemic Disease Spread in Ant Colonies.” ELife, vol. 7, e32073, eLife
Sciences Publications, 2018, doi:10.7554/eLife.32073.
short: C. Pull, L.V. Ugelvig, F. Wiesenhofer, A.V. Grasse, S. Tragust, T. Schmitt,
M. Brown, S. Cremer, ELife 7 (2018).
date_created: 2018-12-11T11:47:31Z
date_published: 2018-01-09T00:00:00Z
date_updated: 2023-09-11T12:54:26Z
day: '09'
ddc:
- '570'
- '590'
department:
- _id: SyCr
doi: 10.7554/eLife.32073
ec_funded: 1
external_id:
isi:
- '000419601300001'
file:
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checksum: 540f941e8d3530a9441e4affd94f07d7
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:10:43Z
date_updated: 2020-07-14T12:47:20Z
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file_name: IST-2018-978-v1+1_elife-32073-v1.pdf
file_size: 1435585
relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: ' 7'
isi: 1
language:
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month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 25DC711C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '243071'
name: 'Social Vaccination in Ant Colonies: from Individual Mechanisms to Society
Effects'
- _id: 25DDF0F0-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '302004'
name: 'Pathogen Detectors Collective disease defence and pathogen detection abilities
in ant societies: a chemo-neuro-immunological approach'
publication: eLife
publication_status: published
publisher: eLife Sciences Publications
publist_id: '7188'
pubrep_id: '978'
quality_controlled: '1'
related_material:
record:
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relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Destructive disinfection of infected brood prevents systemic disease spread
in ant colonies
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 7
year: '2018'
...
---
_id: '413'
abstract:
- lang: eng
text: Being cared for when sick is a benefit of sociality that can reduce disease
and improve survival of group members. However, individuals providing care risk
contracting infectious diseases themselves. If they contract a low pathogen dose,
they may develop low-level infections that do not cause disease but still affect
host immunity by either decreasing or increasing the host’s vulnerability to subsequent
infections. Caring for contagious individuals can thus significantly alter the
future disease susceptibility of caregivers. Using ants and their fungal pathogens
as a model system, we tested if the altered disease susceptibility of experienced
caregivers, in turn, affects their expression of sanitary care behavior. We found
that low-level infections contracted during sanitary care had protective or neutral
effects on secondary exposure to the same (homologous) pathogen but consistently
caused high mortality on superinfection with a different (heterologous) pathogen.
In response to this risk, the ants selectively adjusted the expression of their
sanitary care. Specifically, the ants performed less grooming and more antimicrobial
disinfection when caring for nestmates contaminated with heterologous pathogens
compared with homologous ones. By modulating the components of sanitary care in
this way the ants acquired less infectious particles of the heterologous pathogens,
resulting in reduced superinfection. The performance of risk-adjusted sanitary
care reveals the remarkable capacity of ants to react to changes in their disease
susceptibility, according to their own infection history and to flexibly adjust
collective care to individual risk.
article_processing_charge: No
author:
- first_name: Matthias
full_name: Konrad, Matthias
id: 46528076-F248-11E8-B48F-1D18A9856A87
last_name: Konrad
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Sina
full_name: Metzler, Sina
id: 48204546-F248-11E8-B48F-1D18A9856A87
last_name: Metzler
orcid: 0000-0002-9547-2494
- first_name: Katharina
full_name: Seif, Katharina
id: 90F7894A-02CF-11E9-976E-E38CFE5CBC1D
last_name: Seif
- first_name: Elisabeth
full_name: Naderlinger, Elisabeth
id: 31757262-F248-11E8-B48F-1D18A9856A87
last_name: Naderlinger
- first_name: Anna V
full_name: Grasse, Anna V
id: 406F989C-F248-11E8-B48F-1D18A9856A87
last_name: Grasse
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Konrad M, Pull C, Metzler S, et al. Ants avoid superinfections by performing
risk-adjusted sanitary care. PNAS. 2018;115(11):2782-2787. doi:10.1073/pnas.1713501115
apa: Konrad, M., Pull, C., Metzler, S., Seif, K., Naderlinger, E., Grasse, A. V.,
& Cremer, S. (2018). Ants avoid superinfections by performing risk-adjusted
sanitary care. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1713501115
chicago: Konrad, Matthias, Christopher Pull, Sina Metzler, Katharina Seif, Elisabeth
Naderlinger, Anna V Grasse, and Sylvia Cremer. “Ants Avoid Superinfections by
Performing Risk-Adjusted Sanitary Care.” PNAS. National Academy of Sciences,
2018. https://doi.org/10.1073/pnas.1713501115.
ieee: M. Konrad et al., “Ants avoid superinfections by performing risk-adjusted
sanitary care,” PNAS, vol. 115, no. 11. National Academy of Sciences, pp.
2782–2787, 2018.
ista: Konrad M, Pull C, Metzler S, Seif K, Naderlinger E, Grasse AV, Cremer S. 2018.
Ants avoid superinfections by performing risk-adjusted sanitary care. PNAS. 115(11),
2782–2787.
mla: Konrad, Matthias, et al. “Ants Avoid Superinfections by Performing Risk-Adjusted
Sanitary Care.” PNAS, vol. 115, no. 11, National Academy of Sciences, 2018,
pp. 2782–87, doi:10.1073/pnas.1713501115.
short: M. Konrad, C. Pull, S. Metzler, K. Seif, E. Naderlinger, A.V. Grasse, S.
Cremer, PNAS 115 (2018) 2782–2787.
date_created: 2018-12-11T11:46:20Z
date_published: 2018-03-13T00:00:00Z
date_updated: 2023-09-08T13:22:21Z
day: '13'
department:
- _id: SyCr
doi: 10.1073/pnas.1713501115
ec_funded: 1
external_id:
isi:
- '000427245400069'
pmid:
- '29463746'
intvolume: ' 115'
isi: 1
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/29463746
month: '03'
oa: 1
oa_version: Published Version
page: 2782 - 2787
pmid: 1
project:
- _id: 25DC711C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '243071'
name: 'Social Vaccination in Ant Colonies: from Individual Mechanisms to Society
Effects'
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '7416'
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/helping-in-spite-of-risk-ants-perform-risk-averse-sanitary-care-of-infectious-nest-mates/
scopus_import: '1'
status: public
title: Ants avoid superinfections by performing risk-adjusted sanitary care
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 115
year: '2018'
...
---
_id: '819'
abstract:
- lang: eng
text: 'Contagious diseases must transmit from infectious to susceptible hosts in
order to reproduce. Whilst vectored pathogens can rely on intermediaries to find
new hosts for them, many infectious pathogens require close contact or direct
interaction between hosts for transmission. Hence, this means that conspecifics
are often the main source of infection for most animals and so, in theory, animals
should avoid conspecifics to reduce their risk of infection. Of course, in reality
animals must interact with one another, as a bare minimum, to mate. However, being
social provides many additional benefits and group living has become a taxonomically
diverse and widespread trait. How then do social animals overcome the issue of
increased disease? Over the last few decades, the social insects (ants, termites
and some bees and wasps) have become a model system for studying disease in social
animals. On paper, a social insect colony should be particularly susceptible to
disease, given that they often contain thousands of potential hosts that are closely
related and frequently interact, as well as exhibiting stable environmental conditions
that encourage microbial growth. Yet, disease outbreaks appear to be rare and
attempts to eradicate pest species using pathogens have failed time and again.
Evolutionary biologists investigating this observation have discovered that the
reduced disease susceptibility in social insects is, in part, due to collectively
performed disease defences of the workers. These defences act like a “social immune
system” for the colony, resulting in a per capita decrease in disease, termed
social immunity. Our understanding of social immunity, and its importance in relation
to the immunological defences of each insect, continues to grow, but there remain
many open questions. In this thesis I have studied disease defence in garden ants.
In the first data chapter, I use the invasive garden ant, Lasius neglectus, to
investigate how colonies mitigate lethal infections and prevent them from spreading
systemically. I find that ants have evolved ‘destructive disinfection’ – a behaviour
that uses endogenously produced acidic poison to kill diseased brood and to prevent
the pathogen from replicating. In the second experimental chapter, I continue
to study the use of poison in invasive garden ant colonies, finding that it is
sprayed prophylactically within the nest. However, this spraying has negative
effects on developing pupae when they have had their cocoons artificially removed.
Hence, I suggest that acidic nest sanitation may be maintaining larval cocoon
spinning in this species. In the next experimental chapter, I investigated how
colony founding black garden ant queens (Lasius niger) prevent disease when a
co-foundress dies. I show that ant queens prophylactically perform undertaking
behaviours, similar to those performed by the workers in mature nests. When a
co-foundress was infected, these undertaking behaviours improved the survival
of the healthy queen. In the final data chapter, I explored how immunocompetence
(measured as antifungal activity) changes as incipient black garden ant colonies
grow and mature, from the solitary queen phase to colonies with several hundred
workers. Queen and worker antifungal activity varied throughout this time period,
but despite social immunity, did not decrease as colonies matured. In addition
to the above data chapters, this thesis includes two co-authored reviews. In the
first, we examine the state of the art in the field of social immunity and how
it might develop in the future. In the second, we identify several challenges
and open questions in the study of disease defence in animals. We highlight how
social insects offer a unique model to tackle some of these problems, as disease
defence can be studied from the cell to the society. '
acknowledgement: "ERC FP7 programme (grant agreement no. 240371)\r\nI have been supremely
spoilt to work in a lab with such good resources and I must thank the wonderful
Cremer group technicians, Anna, Barbara, Eva and Florian, for all of their help
and keeping the lab up and running. You guys will probably be the most missed once
I realise just how much work you have been saving me! For the same reason, I must
say a big Dzi ę kuj ę Ci to Wonder Woman Wanda, for her tireless efforts feeding
my colonies and cranking out thousands of petri dishes and sugar tubes. Again, you
will be sorely missed now that I will have to take this task on myself. Of course,
I will be eternally indebted to Prof. Sylvia Cremer for taking me under her wing
and being a constant source of guidance and inspiration. You have given me the perfect
balance of independence and supervision. I cannot thank you enough for creating
such a great working environment and allowing me the freedom to follow my own research
questions. I have had so many exceptional opportunities – attending and presenting
at conferences all over the world, inviting me to write the ARE with you, going
to workshops in Panama and Switzerland, and even organising our own PhD course –
that I often think I must have had the best PhD in the world. You have taught me
so much and made me a scientist. I sincerely hope we get the chance to work together
again in the future. Thank you for everything. I must also thank my PhD Committee,
Daria Siekhaus and Jacobus “Koos” Boomsma, for being very supportive throughout
the duration of my PhD. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
citation:
ama: Pull C. Disease defence in garden ants. 2017. doi:10.15479/AT:ISTA:th_861
apa: Pull, C. (2017). Disease defence in garden ants. Institute of Science
and Technology Austria. https://doi.org/10.15479/AT:ISTA:th_861
chicago: Pull, Christopher. “Disease Defence in Garden Ants.” Institute of Science
and Technology Austria, 2017. https://doi.org/10.15479/AT:ISTA:th_861.
ieee: C. Pull, “Disease defence in garden ants,” Institute of Science and Technology
Austria, 2017.
ista: Pull C. 2017. Disease defence in garden ants. Institute of Science and Technology
Austria.
mla: Pull, Christopher. Disease Defence in Garden Ants. Institute of Science
and Technology Austria, 2017, doi:10.15479/AT:ISTA:th_861.
short: C. Pull, Disease Defence in Garden Ants, Institute of Science and Technology
Austria, 2017.
date_created: 2018-12-11T11:48:40Z
date_published: 2017-09-26T00:00:00Z
date_updated: 2023-09-28T11:31:32Z
day: '26'
ddc:
- '576'
- '577'
- '578'
- '579'
- '590'
- '592'
degree_awarded: PhD
department:
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page: '122'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '6830'
pubrep_id: '861'
related_material:
record:
- id: '616'
relation: part_of_dissertation
status: public
- id: '806'
relation: part_of_dissertation
status: public
- id: '734'
relation: part_of_dissertation
status: public
- id: '732'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Sylvia M
full_name: Cremer, Sylvia M
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
title: Disease defence in garden ants
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2017'
...
---
_id: '732'
abstract:
- lang: eng
text: 'Background: Social insects form densely crowded societies in environments
with high pathogen loads, but have evolved collective defences that mitigate the
impact of disease. However, colony-founding queens lack this protection and suffer
high rates of mortality. The impact of pathogens may be exacerbated in species
where queens found colonies together, as healthy individuals may contract pathogens
from infectious co-founders. Therefore, we tested whether ant queens avoid founding
colonies with pathogen-exposed conspecifics and how they might limit disease transmission
from infectious individuals. Results: Using Lasius Niger queens and a naturally
infecting fungal pathogen Metarhizium brunneum, we observed that queens were equally
likely to found colonies with another pathogen-exposed or sham-treated queen.
However, when one queen died, the surviving individual performed biting, burial
and removal of the corpse. These undertaking behaviours were performed prophylactically,
i.e. targeted equally towards non-infected and infected corpses, as well as carried
out before infected corpses became infectious. Biting and burial reduced the risk
of the queens contracting and dying from disease from an infectious corpse of
a dead co-foundress. Conclusions: We show that co-founding ant queens express
undertaking behaviours that, in mature colonies, are performed exclusively by
workers. Such infection avoidance behaviours act before the queens can contract
the disease and will therefore improve the overall chance of colony founding success
in ant queens.'
article_number: '219'
article_processing_charge: Yes
article_type: original
author:
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Pull C, Cremer S. Co-founding ant queens prevent disease by performing prophylactic
undertaking behaviour. BMC Evolutionary Biology. 2017;17(1). doi:10.1186/s12862-017-1062-4
apa: Pull, C., & Cremer, S. (2017). Co-founding ant queens prevent disease by
performing prophylactic undertaking behaviour. BMC Evolutionary Biology.
BioMed Central. https://doi.org/10.1186/s12862-017-1062-4
chicago: Pull, Christopher, and Sylvia Cremer. “Co-Founding Ant Queens Prevent Disease
by Performing Prophylactic Undertaking Behaviour.” BMC Evolutionary Biology.
BioMed Central, 2017. https://doi.org/10.1186/s12862-017-1062-4.
ieee: C. Pull and S. Cremer, “Co-founding ant queens prevent disease by performing
prophylactic undertaking behaviour,” BMC Evolutionary Biology, vol. 17,
no. 1. BioMed Central, 2017.
ista: Pull C, Cremer S. 2017. Co-founding ant queens prevent disease by performing
prophylactic undertaking behaviour. BMC Evolutionary Biology. 17(1), 219.
mla: Pull, Christopher, and Sylvia Cremer. “Co-Founding Ant Queens Prevent Disease
by Performing Prophylactic Undertaking Behaviour.” BMC Evolutionary Biology,
vol. 17, no. 1, 219, BioMed Central, 2017, doi:10.1186/s12862-017-1062-4.
short: C. Pull, S. Cremer, BMC Evolutionary Biology 17 (2017).
date_created: 2018-12-11T11:48:12Z
date_published: 2017-10-13T00:00:00Z
date_updated: 2023-09-28T11:31:32Z
day: '13'
ddc:
- '576'
- '592'
department:
- _id: SyCr
doi: 10.1186/s12862-017-1062-4
ec_funded: 1
external_id:
isi:
- '000412816800001'
file:
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checksum: 3e24a2cfd48f49f7b3643d08d30fb480
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:18Z
date_updated: 2020-07-14T12:47:55Z
file_id: '5271'
file_name: IST-2017-882-v1+1_12862_2017_Article_1062.pdf
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intvolume: ' 17'
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issue: '1'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 25DC711C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '243071'
name: 'Social Vaccination in Ant Colonies: from Individual Mechanisms to Society
Effects'
publication: BMC Evolutionary Biology
publication_identifier:
issn:
- '14712148'
publication_status: published
publisher: BioMed Central
publist_id: '6937'
pubrep_id: '882'
quality_controlled: '1'
related_material:
record:
- id: '819'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Co-founding ant queens prevent disease by performing prophylactic undertaking
behaviour
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 17
year: '2017'
...
---
_id: '734'
abstract:
- lang: eng
text: 'Social insect societies are long-standing models for understanding social
behaviour and evolution. Unlike other advanced biological societies (such as the
multicellular body), the component parts of social insect societies can be easily
deconstructed and manipulated. Recent methodological and theoretical innovations
have exploited this trait to address an expanded range of biological questions.
We illustrate the broadening range of biological insight coming from social insect
biology with four examples. These new frontiers promote open-minded, interdisciplinary
exploration of one of the richest and most complex of biological phenomena: sociality.'
article_processing_charge: No
article_type: original
author:
- first_name: Patrick
full_name: Kennedy, Patrick
last_name: Kennedy
- first_name: Gemma
full_name: Baron, Gemma
last_name: Baron
- first_name: Bitao
full_name: Qiu, Bitao
last_name: Qiu
- first_name: Dalial
full_name: Freitak, Dalial
last_name: Freitak
- first_name: Heikki
full_name: Helantera, Heikki
last_name: Helantera
- first_name: Edmund
full_name: Hunt, Edmund
last_name: Hunt
- first_name: Fabio
full_name: Manfredini, Fabio
last_name: Manfredini
- first_name: Thomas
full_name: O'Shea Wheller, Thomas
last_name: O'Shea Wheller
- first_name: Solenn
full_name: Patalano, Solenn
last_name: Patalano
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Takao
full_name: Sasaki, Takao
last_name: Sasaki
- first_name: Daisy
full_name: Taylor, Daisy
last_name: Taylor
- first_name: Christopher
full_name: Wyatt, Christopher
last_name: Wyatt
- first_name: Seirian
full_name: Sumner, Seirian
last_name: Sumner
citation:
ama: Kennedy P, Baron G, Qiu B, et al. Deconstructing superorganisms and societies
to address big questions in biology. Trends in Ecology and Evolution. 2017;32(11):861-872.
doi:10.1016/j.tree.2017.08.004
apa: Kennedy, P., Baron, G., Qiu, B., Freitak, D., Helantera, H., Hunt, E., … Sumner,
S. (2017). Deconstructing superorganisms and societies to address big questions
in biology. Trends in Ecology and Evolution. Cell Press. https://doi.org/10.1016/j.tree.2017.08.004
chicago: Kennedy, Patrick, Gemma Baron, Bitao Qiu, Dalial Freitak, Heikki Helantera,
Edmund Hunt, Fabio Manfredini, et al. “Deconstructing Superorganisms and Societies
to Address Big Questions in Biology.” Trends in Ecology and Evolution.
Cell Press, 2017. https://doi.org/10.1016/j.tree.2017.08.004.
ieee: P. Kennedy et al., “Deconstructing superorganisms and societies to
address big questions in biology,” Trends in Ecology and Evolution, vol.
32, no. 11. Cell Press, pp. 861–872, 2017.
ista: Kennedy P, Baron G, Qiu B, Freitak D, Helantera H, Hunt E, Manfredini F, O’Shea
Wheller T, Patalano S, Pull C, Sasaki T, Taylor D, Wyatt C, Sumner S. 2017. Deconstructing
superorganisms and societies to address big questions in biology. Trends in Ecology
and Evolution. 32(11), 861–872.
mla: Kennedy, Patrick, et al. “Deconstructing Superorganisms and Societies to Address
Big Questions in Biology.” Trends in Ecology and Evolution, vol. 32, no.
11, Cell Press, 2017, pp. 861–72, doi:10.1016/j.tree.2017.08.004.
short: P. Kennedy, G. Baron, B. Qiu, D. Freitak, H. Helantera, E. Hunt, F. Manfredini,
T. O’Shea Wheller, S. Patalano, C. Pull, T. Sasaki, D. Taylor, C. Wyatt, S. Sumner,
Trends in Ecology and Evolution 32 (2017) 861–872.
date_created: 2018-12-11T11:48:13Z
date_published: 2017-11-01T00:00:00Z
date_updated: 2023-09-27T14:15:15Z
day: '01'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.1016/j.tree.2017.08.004
external_id:
isi:
- '000413231900011'
file:
- access_level: open_access
checksum: c8f49309ed9436201814fa7153d66a99
content_type: application/pdf
creator: dernst
date_created: 2020-05-14T16:22:27Z
date_updated: 2020-07-14T12:47:56Z
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file_name: 2017_TrendsEcology_Kennedy.pdf
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issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
page: 861 - 872
publication: Trends in Ecology and Evolution
publication_identifier:
issn:
- '01695347'
publication_status: published
publisher: Cell Press
publist_id: '6933'
quality_controlled: '1'
related_material:
record:
- id: '819'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Deconstructing superorganisms and societies to address big questions in biology
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 32
year: '2017'
...
---
_id: '2086'
abstract:
- lang: eng
text: Pathogens may gain a fitness advantage through manipulation of the behaviour
of their hosts. Likewise, host behavioural changes can be a defence mechanism,
counteracting the impact of pathogens on host fitness. We apply harmonic radar
technology to characterize the impact of an emerging pathogen - Nosema ceranae
(Microsporidia) - on honeybee (Apis mellifera) flight and orientation performance
in the field. Honeybees are the most important commercial pollinators. Emerging
diseases have been proposed to play a prominent role in colony decline, partly
through sub-lethal behavioural manipulation of their hosts. We found that homing
success was significantly reduced in diseased (65.8%) versus healthy foragers
(92.5%). Although lost bees had significantly reduced continuous flight times
and prolonged resting times, other flight characteristics and navigational abilities
showed no significant difference between infected and non-infected bees. Our results
suggest that infected bees express normal flight characteristics but are constrained
in their homing ability, potentially compromising the colony by reducing its resource
inputs, but also counteracting the intra-colony spread of infection. We provide
the first high-resolution analysis of sub-lethal effects of an emerging disease
on insect flight behaviour. The potential causes and the implications for both
host and parasite are discussed.
acknowledgement: This study was funded jointly by a grant from BBSRC, Defra, NERC,
the Scottish Government and the Wellcome Trust, under the Insect Pollinators Initiative
(grant numbers BB/I00097/1 and BB/I000100/1). Rothamsted Research is a national
institute of bioscience strategically funded by the UK Biotechnology and Biological
Sciences Research Council (BBSRC).
article_number: e103989
author:
- first_name: Stephan
full_name: Wolf, Stephan
last_name: Wolf
- first_name: Dino
full_name: Mcmahon, Dino
last_name: Mcmahon
- first_name: Ka
full_name: Lim, Ka
last_name: Lim
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Suzanne
full_name: Clark, Suzanne
last_name: Clark
- first_name: Robert
full_name: Paxton, Robert
last_name: Paxton
- first_name: Juliet
full_name: Osborne, Juliet
last_name: Osborne
citation:
ama: 'Wolf S, Mcmahon D, Lim K, et al. So near and yet so far: Harmonic radar reveals
reduced homing ability of Nosema infected honeybees. PLoS One. 2014;9(8).
doi:10.1371/journal.pone.0103989'
apa: 'Wolf, S., Mcmahon, D., Lim, K., Pull, C., Clark, S., Paxton, R., & Osborne,
J. (2014). So near and yet so far: Harmonic radar reveals reduced homing ability
of Nosema infected honeybees. PLoS One. Public Library of Science. https://doi.org/10.1371/journal.pone.0103989'
chicago: 'Wolf, Stephan, Dino Mcmahon, Ka Lim, Christopher Pull, Suzanne Clark,
Robert Paxton, and Juliet Osborne. “So near and yet so Far: Harmonic Radar Reveals
Reduced Homing Ability of Nosema Infected Honeybees.” PLoS One. Public
Library of Science, 2014. https://doi.org/10.1371/journal.pone.0103989.'
ieee: 'S. Wolf et al., “So near and yet so far: Harmonic radar reveals reduced
homing ability of Nosema infected honeybees,” PLoS One, vol. 9, no. 8.
Public Library of Science, 2014.'
ista: 'Wolf S, Mcmahon D, Lim K, Pull C, Clark S, Paxton R, Osborne J. 2014. So
near and yet so far: Harmonic radar reveals reduced homing ability of Nosema infected
honeybees. PLoS One. 9(8), e103989.'
mla: 'Wolf, Stephan, et al. “So near and yet so Far: Harmonic Radar Reveals Reduced
Homing Ability of Nosema Infected Honeybees.” PLoS One, vol. 9, no. 8,
e103989, Public Library of Science, 2014, doi:10.1371/journal.pone.0103989.'
short: S. Wolf, D. Mcmahon, K. Lim, C. Pull, S. Clark, R. Paxton, J. Osborne, PLoS
One 9 (2014).
date_created: 2018-12-11T11:55:37Z
date_published: 2014-08-06T00:00:00Z
date_updated: 2023-02-23T14:11:56Z
day: '06'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.1371/journal.pone.0103989
file:
- access_level: open_access
checksum: 2fc62c6739eada4bddf026afbae669db
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:55Z
date_updated: 2020-07-14T12:45:28Z
file_id: '5042'
file_name: IST-2016-437-v1+1_journal.pone.0103989.pdf
file_size: 1013386
relation: main_file
file_date_updated: 2020-07-14T12:45:28Z
has_accepted_license: '1'
intvolume: ' 9'
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '4949'
pubrep_id: '437'
quality_controlled: '1'
related_material:
record:
- id: '9888'
relation: research_data
status: public
scopus_import: 1
status: public
title: 'So near and yet so far: Harmonic radar reveals reduced homing ability of Nosema
infected honeybees'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2014'
...
---
_id: '9888'
abstract:
- lang: eng
text: Detailed description of the experimental prodedures, data analyses and additional
statistical analyses of the results.
article_processing_charge: No
author:
- first_name: Stephan
full_name: Wolf, Stephan
last_name: Wolf
- first_name: Dino
full_name: Mcmahon, Dino
last_name: Mcmahon
- first_name: Ka
full_name: Lim, Ka
last_name: Lim
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Suzanne
full_name: Clark, Suzanne
last_name: Clark
- first_name: Robert
full_name: Paxton, Robert
last_name: Paxton
- first_name: Juliet
full_name: Osborne, Juliet
last_name: Osborne
citation:
ama: Wolf S, Mcmahon D, Lim K, et al. Supporting information. 2014. doi:10.1371/journal.pone.0103989.s003
apa: Wolf, S., Mcmahon, D., Lim, K., Pull, C., Clark, S., Paxton, R., & Osborne,
J. (2014). Supporting information. Public Library of Science. https://doi.org/10.1371/journal.pone.0103989.s003
chicago: Wolf, Stephan, Dino Mcmahon, Ka Lim, Christopher Pull, Suzanne Clark, Robert
Paxton, and Juliet Osborne. “Supporting Information.” Public Library of Science,
2014. https://doi.org/10.1371/journal.pone.0103989.s003.
ieee: S. Wolf et al., “Supporting information.” Public Library of Science,
2014.
ista: Wolf S, Mcmahon D, Lim K, Pull C, Clark S, Paxton R, Osborne J. 2014. Supporting
information, Public Library of Science, 10.1371/journal.pone.0103989.s003.
mla: Wolf, Stephan, et al. Supporting Information. Public Library of Science,
2014, doi:10.1371/journal.pone.0103989.s003.
short: S. Wolf, D. Mcmahon, K. Lim, C. Pull, S. Clark, R. Paxton, J. Osborne, (2014).
date_created: 2021-08-11T14:17:53Z
date_updated: 2023-02-23T10:27:38Z
day: '06'
department:
- _id: SyCr
doi: 10.1371/journal.pone.0103989.s003
month: '08'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '2086'
relation: used_in_publication
status: public
status: public
title: Supporting information
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2014'
...
---
_id: '2283'
abstract:
- lang: eng
text: Pathogens exert a strong selection pressure on organisms to evolve effective
immune defences. In addition to individual immunity, social organisms can act
cooperatively to produce collective defences. In many ant species, queens have
the option to found a colony alone or in groups with other, often unrelated, conspecifics.
These associations are transient, usually lasting only as long as each queen benefits
from the presence of others. In fact, once the first workers emerge, queens fight
to the death for dominance. One potential advantage of co-founding may be that
queens benefit from collective disease defences, such as mutual grooming, that
act against common soil pathogens. We test this hypothesis by exposing single
and co-founding queens to a fungal parasite, in order to assess whether queens
in co-founding associations have improved survival. Surprisingly, co-foundresses
exposed to the entomopathogenic fungus Metarhizium did not engage in cooperative
disease defences, and consequently, we find no direct benefit of multiple queens
on survival. However, an indirect benefit was observed, with parasite-exposed
queens producing more brood when they co-founded, than when they were alone. We
suggest this is due to a trade-off between reproduction and immunity. Additionally,
we report an extraordinary ability of the queens to tolerate an infection for
long periods after parasite exposure. Our study suggests that there are no social
immunity benefits for co-founding ant queens, but that in parasite-rich environments,
the presence of additional queens may nevertheless improve the chances of colony
founding success.
author:
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: William
full_name: Hughes, William
last_name: Hughes
- first_name: Markus
full_name: Brown, Markus
id: 3DAB9AFC-F248-11E8-B48F-1D18A9856A87
last_name: Brown
citation:
ama: 'Pull C, Hughes W, Brown M. Tolerating an infection: an indirect benefit of
co-founding queen associations in the ant Lasius niger . Naturwissenschaften.
2013;100(12):1125-1136. doi:10.1007/s00114-013-1115-5'
apa: 'Pull, C., Hughes, W., & Brown, M. (2013). Tolerating an infection: an
indirect benefit of co-founding queen associations in the ant Lasius niger . Naturwissenschaften.
Springer. https://doi.org/10.1007/s00114-013-1115-5'
chicago: 'Pull, Christopher, William Hughes, and Markus Brown. “Tolerating an Infection:
An Indirect Benefit of Co-Founding Queen Associations in the Ant Lasius Niger
.” Naturwissenschaften. Springer, 2013. https://doi.org/10.1007/s00114-013-1115-5.'
ieee: 'C. Pull, W. Hughes, and M. Brown, “Tolerating an infection: an indirect benefit
of co-founding queen associations in the ant Lasius niger ,” Naturwissenschaften,
vol. 100, no. 12. Springer, pp. 1125–1136, 2013.'
ista: 'Pull C, Hughes W, Brown M. 2013. Tolerating an infection: an indirect benefit
of co-founding queen associations in the ant Lasius niger . Naturwissenschaften.
100(12), 1125–1136.'
mla: 'Pull, Christopher, et al. “Tolerating an Infection: An Indirect Benefit of
Co-Founding Queen Associations in the Ant Lasius Niger .” Naturwissenschaften,
vol. 100, no. 12, Springer, 2013, pp. 1125–36, doi:10.1007/s00114-013-1115-5.'
short: C. Pull, W. Hughes, M. Brown, Naturwissenschaften 100 (2013) 1125–1136.
date_created: 2018-12-11T11:56:45Z
date_published: 2013-11-14T00:00:00Z
date_updated: 2021-01-12T06:56:31Z
day: '14'
department:
- _id: SyCr
doi: 10.1007/s00114-013-1115-5
intvolume: ' 100'
issue: '12'
language:
- iso: eng
month: '11'
oa_version: None
page: 1125 - 1136
publication: Naturwissenschaften
publication_status: published
publisher: Springer
publist_id: '4649'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Tolerating an infection: an indirect benefit of co-founding queen associations
in the ant Lasius niger '
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 100
year: '2013'
...