---
_id: '7932'
abstract:
- lang: eng
  text: Pulsating flows through tubular geometries are laminar provided that velocities
    are moderate. This in particular is also believed to apply to cardiovascular flows
    where inertial forces are typically too low to sustain turbulence. On the other
    hand, flow instabilities and fluctuating shear stresses are held responsible for
    a variety of cardiovascular diseases. Here we report a nonlinear instability mechanism
    for pulsating pipe flow that gives rise to bursts of turbulence at low flow rates.
    Geometrical distortions of small, yet finite, amplitude are found to excite a
    state consisting of helical vortices during flow deceleration. The resulting flow
    pattern grows rapidly in magnitude, breaks down into turbulence, and eventually
    returns to laminar when the flow accelerates. This scenario causes shear stress
    fluctuations and flow reversal during each pulsation cycle. Such unsteady conditions
    can adversely affect blood vessels and have been shown to promote inflammation
    and dysfunction of the shear stress-sensitive endothelial cell layer.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Duo
  full_name: Xu, Duo
  id: 3454D55E-F248-11E8-B48F-1D18A9856A87
  last_name: Xu
- first_name: Atul
  full_name: Varshney, Atul
  id: 2A2006B2-F248-11E8-B48F-1D18A9856A87
  last_name: Varshney
  orcid: 0000-0002-3072-5999
- first_name: Xingyu
  full_name: Ma, Xingyu
  id: 34BADBA6-F248-11E8-B48F-1D18A9856A87
  last_name: Ma
  orcid: 0000-0002-0179-9737
- first_name: Baofang
  full_name: Song, Baofang
  last_name: Song
- first_name: Michael
  full_name: Riedl, Michael
  id: 3BE60946-F248-11E8-B48F-1D18A9856A87
  last_name: Riedl
  orcid: 0000-0003-4844-6311
- first_name: Marc
  full_name: Avila, Marc
  last_name: Avila
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Xu D, Varshney A, Ma X, et al. Nonlinear hydrodynamic instability and turbulence
    in pulsatile flow. <i>Proceedings of the National Academy of Sciences of the United
    States of America</i>. 2020;117(21):11233-11239. doi:<a href="https://doi.org/10.1073/pnas.1913716117">10.1073/pnas.1913716117</a>
  apa: Xu, D., Varshney, A., Ma, X., Song, B., Riedl, M., Avila, M., &#38; Hof, B.
    (2020). Nonlinear hydrodynamic instability and turbulence in pulsatile flow. <i>Proceedings
    of the National Academy of Sciences of the United States of America</i>. National
    Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1913716117">https://doi.org/10.1073/pnas.1913716117</a>
  chicago: Xu, Duo, Atul Varshney, Xingyu Ma, Baofang Song, Michael Riedl, Marc Avila,
    and Björn Hof. “Nonlinear Hydrodynamic Instability and Turbulence in Pulsatile
    Flow.” <i>Proceedings of the National Academy of Sciences of the United States
    of America</i>. National Academy of Sciences, 2020. <a href="https://doi.org/10.1073/pnas.1913716117">https://doi.org/10.1073/pnas.1913716117</a>.
  ieee: D. Xu <i>et al.</i>, “Nonlinear hydrodynamic instability and turbulence in
    pulsatile flow,” <i>Proceedings of the National Academy of Sciences of the United
    States of America</i>, vol. 117, no. 21. National Academy of Sciences, pp. 11233–11239,
    2020.
  ista: Xu D, Varshney A, Ma X, Song B, Riedl M, Avila M, Hof B. 2020. Nonlinear hydrodynamic
    instability and turbulence in pulsatile flow. Proceedings of the National Academy
    of Sciences of the United States of America. 117(21), 11233–11239.
  mla: Xu, Duo, et al. “Nonlinear Hydrodynamic Instability and Turbulence in Pulsatile
    Flow.” <i>Proceedings of the National Academy of Sciences of the United States
    of America</i>, vol. 117, no. 21, National Academy of Sciences, 2020, pp. 11233–39,
    doi:<a href="https://doi.org/10.1073/pnas.1913716117">10.1073/pnas.1913716117</a>.
  short: D. Xu, A. Varshney, X. Ma, B. Song, M. Riedl, M. Avila, B. Hof, Proceedings
    of the National Academy of Sciences of the United States of America 117 (2020)
    11233–11239.
date_created: 2020-06-07T22:00:51Z
date_published: 2020-05-26T00:00:00Z
date_updated: 2023-11-30T10:55:13Z
day: '26'
department:
- _id: BjHo
doi: 10.1073/pnas.1913716117
ec_funded: 1
external_id:
  arxiv:
  - '2005.11190'
  isi:
  - '000536797100014'
intvolume: '       117'
isi: 1
issue: '21'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2005.11190
month: '05'
oa: 1
oa_version: Preprint
page: 11233-11239
project:
- _id: 238B8092-32DE-11EA-91FC-C7463DDC885E
  call_identifier: FWF
  grant_number: I04188
  name: Instabilities in pulsating pipe flow of Newtonian and complex fluids
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the National Academy of Sciences of the United States
  of America
publication_identifier:
  eissn:
  - '10916490'
  issn:
  - '00278424'
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/blood-flows-more-turbulent-than-previously-expected/
  record:
  - id: '12726'
    relation: dissertation_contains
    status: public
  - id: '14530'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Nonlinear hydrodynamic instability and turbulence in pulsatile flow
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 117
year: '2020'
...
---
_id: '745'
abstract:
- lang: eng
  text: 'Fluid flows in nature and applications are frequently subject to periodic
    velocity modulations. Surprisingly, even for the generic case of flow through
    a straight pipe, there is little consensus regarding the influence of pulsation
    on the transition threshold to turbulence: while most studies predict a monotonically
    increasing threshold with pulsation frequency (i.e. Womersley number, ), others
    observe a decreasing threshold for identical parameters and only observe an increasing
    threshold at low . In the present study we apply recent advances in the understanding
    of transition in steady shear flows to pulsating pipe flow. For moderate pulsation
    amplitudes we find that the first instability encountered is subcritical (i.e.
    requiring finite amplitude disturbances) and gives rise to localized patches of
    turbulence (''puffs'') analogous to steady pipe flow. By monitoring the impact
    of pulsation on the lifetime of turbulence we map the onset of turbulence in parameter
    space. Transition in pulsatile flow can be separated into three regimes. At small
    Womersley numbers the dynamics is dominated by the decay turbulence suffers during
    the slower part of the cycle and hence transition is delayed significantly. As
    shown in this regime thresholds closely agree with estimates based on a quasi-steady
    flow assumption only taking puff decay rates into account. The transition point
    predicted in the zero limit equals to the critical point for steady pipe flow
    offset by the oscillation Reynolds number (i.e. the dimensionless oscillation
    amplitude). In the high frequency limit on the other hand, puff lifetimes are
    identical to those in steady pipe flow and hence the transition threshold appears
    to be unaffected by flow pulsation. In the intermediate frequency regime the transition
    threshold sharply drops (with increasing ) from the decay dominated (quasi-steady)
    threshold to the steady pipe flow level.'
article_processing_charge: No
author:
- first_name: Duo
  full_name: Xu, Duo
  id: 3454D55E-F248-11E8-B48F-1D18A9856A87
  last_name: Xu
- first_name: Sascha
  full_name: Warnecke, Sascha
  last_name: Warnecke
- first_name: Baofang
  full_name: Song, Baofang
  last_name: Song
- first_name: Xingyu
  full_name: Ma, Xingyu
  id: 34BADBA6-F248-11E8-B48F-1D18A9856A87
  last_name: Ma
  orcid: 0000-0002-0179-9737
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Xu D, Warnecke S, Song B, Ma X, Hof B. Transition to turbulence in pulsating
    pipe flow. <i>Journal of Fluid Mechanics</i>. 2017;831:418-432. doi:<a href="https://doi.org/10.1017/jfm.2017.620">10.1017/jfm.2017.620</a>
  apa: Xu, D., Warnecke, S., Song, B., Ma, X., &#38; Hof, B. (2017). Transition to
    turbulence in pulsating pipe flow. <i>Journal of Fluid Mechanics</i>. Cambridge
    University Press. <a href="https://doi.org/10.1017/jfm.2017.620">https://doi.org/10.1017/jfm.2017.620</a>
  chicago: Xu, Duo, Sascha Warnecke, Baofang Song, Xingyu Ma, and Björn Hof. “Transition
    to Turbulence in Pulsating Pipe Flow.” <i>Journal of Fluid Mechanics</i>. Cambridge
    University Press, 2017. <a href="https://doi.org/10.1017/jfm.2017.620">https://doi.org/10.1017/jfm.2017.620</a>.
  ieee: D. Xu, S. Warnecke, B. Song, X. Ma, and B. Hof, “Transition to turbulence
    in pulsating pipe flow,” <i>Journal of Fluid Mechanics</i>, vol. 831. Cambridge
    University Press, pp. 418–432, 2017.
  ista: Xu D, Warnecke S, Song B, Ma X, Hof B. 2017. Transition to turbulence in pulsating
    pipe flow. Journal of Fluid Mechanics. 831, 418–432.
  mla: Xu, Duo, et al. “Transition to Turbulence in Pulsating Pipe Flow.” <i>Journal
    of Fluid Mechanics</i>, vol. 831, Cambridge University Press, 2017, pp. 418–32,
    doi:<a href="https://doi.org/10.1017/jfm.2017.620">10.1017/jfm.2017.620</a>.
  short: D. Xu, S. Warnecke, B. Song, X. Ma, B. Hof, Journal of Fluid Mechanics 831
    (2017) 418–432.
date_created: 2018-12-11T11:48:17Z
date_published: 2017-11-25T00:00:00Z
date_updated: 2023-09-27T12:28:12Z
day: '25'
department:
- _id: BjHo
doi: 10.1017/jfm.2017.620
ec_funded: 1
external_id:
  isi:
  - '000412934800005'
intvolume: '       831'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1709.03738
month: '11'
oa: 1
oa_version: Submitted Version
page: 418 - 432
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '306589'
  name: Decoding the complexity of turbulence at its origin
publication: Journal of Fluid Mechanics
publication_identifier:
  issn:
  - '00221120'
publication_status: published
publisher: Cambridge University Press
publist_id: '6922'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transition to turbulence in pulsating pipe flow
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 831
year: '2017'
...
---
_id: '1339'
abstract:
- lang: eng
  text: "We present a microelectromechanical system, in which a silicon beam is attached
    to a comb-drive\r\nactuator, which is used to tune the tension in the silicon
    beam and thus its resonance frequency. By\r\nmeasuring the resonance frequencies
    of the system, we show that the comb-drive actuator and the\r\nsilicon beam behave
    as two strongly coupled resonators. Interestingly, the effective coupling rate\r\n(1.5
    MHz) is tunable with the comb-drive actuator (10%) as well as with a side-gate
    (10%)\r\nplaced close to the silicon beam. In contrast, the effective spring constant
    of the system is insensitive\r\nto either of them and changes only by 60.5%. Finally,
    we show that the comb-drive actuator\r\ncan be used to switch between different
    coupling rates with a frequency of at least 10 kHz.\r\n"
acknowledgement: We acknowledge the support from the Helmholtz Nanoelectronic Facility
  (HNF) and funding from the ERC (GA-Nr. 280140).
article_number: '143507'
author:
- first_name: Gerard
  full_name: Verbiest, Gerard
  last_name: Verbiest
- first_name: Duo
  full_name: Xu, Duo
  id: 3454D55E-F248-11E8-B48F-1D18A9856A87
  last_name: Xu
- first_name: Matthias
  full_name: Goldsche, Matthias
  last_name: Goldsche
- first_name: Timofiy
  full_name: Khodkov, Timofiy
  last_name: Khodkov
- first_name: Shabir
  full_name: Barzanjeh, Shabir
  id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
  last_name: Barzanjeh
  orcid: 0000-0003-0415-1423
- first_name: Nils
  full_name: Von Den Driesch, Nils
  last_name: Von Den Driesch
- first_name: Dan
  full_name: Buca, Dan
  last_name: Buca
- first_name: Christoph
  full_name: Stampfer, Christoph
  last_name: Stampfer
citation:
  ama: Verbiest G, Xu D, Goldsche M, et al. Tunable mechanical coupling between driven
    microelectromechanical resonators. <i>Applied  Physics Letter</i>. 2016;109. doi:<a
    href="https://doi.org/10.1063/1.4964122">10.1063/1.4964122</a>
  apa: Verbiest, G., Xu, D., Goldsche, M., Khodkov, T., Barzanjeh, S., Von Den Driesch,
    N., … Stampfer, C. (2016). Tunable mechanical coupling between driven microelectromechanical
    resonators. <i>Applied  Physics Letter</i>. American Institute of Physics. <a
    href="https://doi.org/10.1063/1.4964122">https://doi.org/10.1063/1.4964122</a>
  chicago: Verbiest, Gerard, Duo Xu, Matthias Goldsche, Timofiy Khodkov, Shabir Barzanjeh,
    Nils Von Den Driesch, Dan Buca, and Christoph Stampfer. “Tunable Mechanical Coupling
    between Driven Microelectromechanical Resonators.” <i>Applied  Physics Letter</i>.
    American Institute of Physics, 2016. <a href="https://doi.org/10.1063/1.4964122">https://doi.org/10.1063/1.4964122</a>.
  ieee: G. Verbiest <i>et al.</i>, “Tunable mechanical coupling between driven microelectromechanical
    resonators,” <i>Applied  Physics Letter</i>, vol. 109. American Institute of Physics,
    2016.
  ista: Verbiest G, Xu D, Goldsche M, Khodkov T, Barzanjeh S, Von Den Driesch N, Buca
    D, Stampfer C. 2016. Tunable mechanical coupling between driven microelectromechanical
    resonators. Applied  Physics Letter. 109, 143507.
  mla: Verbiest, Gerard, et al. “Tunable Mechanical Coupling between Driven Microelectromechanical
    Resonators.” <i>Applied  Physics Letter</i>, vol. 109, 143507, American Institute
    of Physics, 2016, doi:<a href="https://doi.org/10.1063/1.4964122">10.1063/1.4964122</a>.
  short: G. Verbiest, D. Xu, M. Goldsche, T. Khodkov, S. Barzanjeh, N. Von Den Driesch,
    D. Buca, C. Stampfer, Applied  Physics Letter 109 (2016).
date_created: 2018-12-11T11:51:28Z
date_published: 2016-10-04T00:00:00Z
date_updated: 2023-02-21T10:35:06Z
day: '04'
department:
- _id: JoFi
doi: 10.1063/1.4964122
intvolume: '       109'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1607.04406
month: '10'
oa: 1
oa_version: Preprint
publication: Applied  Physics Letter
publication_status: published
publisher: American Institute of Physics
publist_id: '5928'
quality_controlled: '1'
scopus_import: 1
status: public
title: Tunable mechanical coupling between driven microelectromechanical resonators
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 109
year: '2016'
...
