---
_id: '10583'
abstract:
- lang: eng
text: The synthetic strigolactone (SL) analog, rac-GR24, has been instrumental in
studying the role of SLs as well as karrikins because it activates the receptors
DWARF14 (D14) and KARRIKIN INSENSITIVE 2 (KAI2) of their signaling pathways, respectively.
Treatment with rac-GR24 modifies the root architecture at different levels, such
as decreasing the lateral root density (LRD), while promoting root hair elongation
or flavonol accumulation. Previously, we have shown that the flavonol biosynthesis
is transcriptionally activated in the root by rac-GR24 treatment, but, thus far,
the molecular players involved in that response have remained unknown. To get
an in-depth insight into the changes that occur after the compound is perceived
by the roots, we compared the root transcriptomes of the wild type and the more
axillary growth2 (max2) mutant, affected in both SL and karrikin signaling pathways,
with and without rac-GR24 treatment. Quantitative reverse transcription (qRT)-PCR,
reporter line analysis and mutant phenotyping indicated that the flavonol response
and the root hair elongation are controlled by the ELONGATED HYPOCOTYL 5 (HY5)
and MYB12 transcription factors, but HY5, in contrast to MYB12, affects the LRD
as well. Furthermore, we identified the transcription factors TARGET OF MONOPTEROS
5 (TMO5) and TMO5 LIKE1 as negative and the Mediator complex as positive regulators
of the rac-GR24 effect on LRD. Altogether, hereby, we get closer toward understanding
the molecular mechanisms that underlay the rac-GR24 responses in the root.
acknowledgement: The authors thank Ralf Stracke (Bielefeld University, Bielefeld,
Germany) for providing the myb mutants and their colleagues Bert De Rybel for the
tmo5t;mo5l1 double mutant, Boris Parizot for tips on the RNA-seq analysis, Veronique
Storme for statistical help on both the RNA-seq and lateral root density, and Martine
De Cock for help in preparing the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Sylwia
full_name: Struk, Sylwia
last_name: Struk
- first_name: Lukas
full_name: Braem, Lukas
last_name: Braem
- first_name: Cedrick
full_name: Matthys, Cedrick
last_name: Matthys
- first_name: Alan
full_name: Walton, Alan
last_name: Walton
- first_name: Nick
full_name: Vangheluwe, Nick
last_name: Vangheluwe
- first_name: Stan
full_name: Van Praet, Stan
last_name: Van Praet
- first_name: Lingxiang
full_name: Jiang, Lingxiang
last_name: Jiang
- first_name: Pawel
full_name: Baster, Pawel
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Carolien
full_name: De Cuyper, Carolien
last_name: De Cuyper
- first_name: Francois-Didier
full_name: Boyer, Francois-Didier
last_name: Boyer
- first_name: Elisabeth
full_name: Stes, Elisabeth
last_name: Stes
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Kris
full_name: Gevaert, Kris
last_name: Gevaert
- first_name: Sofie
full_name: Goormachtig, Sofie
last_name: Goormachtig
citation:
ama: Struk S, Braem L, Matthys C, et al. Transcriptional analysis in the Arabidopsis
roots reveals new regulators that link rac-GR24 treatment with changes in flavonol
accumulation, root hair elongation and lateral root density. Plant & Cell
Physiology. 2022;63(1):104-119. doi:10.1093/pcp/pcab149
apa: Struk, S., Braem, L., Matthys, C., Walton, A., Vangheluwe, N., Van Praet, S.,
… Goormachtig, S. (2022). Transcriptional analysis in the Arabidopsis roots reveals
new regulators that link rac-GR24 treatment with changes in flavonol accumulation,
root hair elongation and lateral root density. Plant & Cell Physiology.
Oxford University Press. https://doi.org/10.1093/pcp/pcab149
chicago: Struk, Sylwia, Lukas Braem, Cedrick Matthys, Alan Walton, Nick Vangheluwe,
Stan Van Praet, Lingxiang Jiang, et al. “Transcriptional Analysis in the Arabidopsis
Roots Reveals New Regulators That Link Rac-GR24 Treatment with Changes in Flavonol
Accumulation, Root Hair Elongation and Lateral Root Density.” Plant & Cell
Physiology. Oxford University Press, 2022. https://doi.org/10.1093/pcp/pcab149.
ieee: S. Struk et al., “Transcriptional analysis in the Arabidopsis roots
reveals new regulators that link rac-GR24 treatment with changes in flavonol accumulation,
root hair elongation and lateral root density,” Plant & Cell Physiology,
vol. 63, no. 1. Oxford University Press, pp. 104–119, 2022.
ista: Struk S, Braem L, Matthys C, Walton A, Vangheluwe N, Van Praet S, Jiang L,
Baster P, De Cuyper C, Boyer F-D, Stes E, Beeckman T, Friml J, Gevaert K, Goormachtig
S. 2022. Transcriptional analysis in the Arabidopsis roots reveals new regulators
that link rac-GR24 treatment with changes in flavonol accumulation, root hair
elongation and lateral root density. Plant & Cell Physiology. 63(1), 104–119.
mla: Struk, Sylwia, et al. “Transcriptional Analysis in the Arabidopsis Roots Reveals
New Regulators That Link Rac-GR24 Treatment with Changes in Flavonol Accumulation,
Root Hair Elongation and Lateral Root Density.” Plant & Cell Physiology,
vol. 63, no. 1, Oxford University Press, 2022, pp. 104–19, doi:10.1093/pcp/pcab149.
short: S. Struk, L. Braem, C. Matthys, A. Walton, N. Vangheluwe, S. Van Praet, L.
Jiang, P. Baster, C. De Cuyper, F.-D. Boyer, E. Stes, T. Beeckman, J. Friml, K.
Gevaert, S. Goormachtig, Plant & Cell Physiology 63 (2022) 104–119.
date_created: 2021-12-28T11:44:18Z
date_published: 2022-01-21T00:00:00Z
date_updated: 2023-08-02T13:40:43Z
day: '21'
department:
- _id: JiFr
doi: 10.1093/pcp/pcab149
external_id:
isi:
- '000877899400009'
pmid:
- '34791413'
intvolume: ' 63'
isi: 1
issue: '1'
keyword:
- flavonols
- MAX2
- rac-Gr24
- RNA-seq
- root development
- transcriptional regulation
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/pcp/pcab149
month: '01'
oa: 1
oa_version: Published Version
page: 104-119
pmid: 1
publication: Plant & Cell Physiology
publication_identifier:
eissn:
- 1471-9053
issn:
- 0032-0781
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transcriptional analysis in the Arabidopsis roots reveals new regulators that
link rac-GR24 treatment with changes in flavonol accumulation, root hair elongation
and lateral root density
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 63
year: '2022'
...
---
_id: '1806'
abstract:
- lang: eng
text: The generation of asymmetry, at both cellular and tissue level, is one of
the most essential capabilities of all eukaryotic organisms. It mediates basically
all multicellular development ranging from embryogenesis and de novo organ formation
till responses to various environmental stimuli. In plants, the awe-inspiring
number of such processes is regulated by phytohormone auxin and its directional,
cell-to-cell transport. The mediators of this transport, PIN auxin transporters,
are asymmetrically localized at the plasma membrane, and this polar localization
determines the directionality of intercellular auxin flow. Thus, auxin transport
contributes crucially to the generation of local auxin gradients or maxima, which
instruct given cell to change its developmental program. Here, we introduce and
discuss the molecular components and cellular mechanisms regulating the generation
and maintenance of cellular PIN polarity, as the general hallmarks of cell polarity
in plants.
author:
- first_name: Pawel
full_name: Baster, Pawel
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: 'Baster P, Friml J. Auxin on the road navigated by cellular PIN polarity. In:
Zažímalová E, Petrášek J, Benková E, eds. Auxin and Its Role in Plant Development.
Springer; 2014:143-170. doi:10.1007/978-3-7091-1526-8_8'
apa: Baster, P., & Friml, J. (2014). Auxin on the road navigated by cellular
PIN polarity. In E. Zažímalová, J. Petrášek, & E. Benková (Eds.), Auxin
and Its Role in Plant Development (pp. 143–170). Springer. https://doi.org/10.1007/978-3-7091-1526-8_8
chicago: Baster, Pawel, and Jiří Friml. “Auxin on the Road Navigated by Cellular
PIN Polarity.” In Auxin and Its Role in Plant Development, edited by Eva
Zažímalová, Jan Petrášek, and Eva Benková, 143–70. Springer, 2014. https://doi.org/10.1007/978-3-7091-1526-8_8.
ieee: P. Baster and J. Friml, “Auxin on the road navigated by cellular PIN polarity,”
in Auxin and Its Role in Plant Development, E. Zažímalová, J. Petrášek,
and E. Benková, Eds. Springer, 2014, pp. 143–170.
ista: 'Baster P, Friml J. 2014.Auxin on the road navigated by cellular PIN polarity.
In: Auxin and Its Role in Plant Development. , 143–170.'
mla: Baster, Pawel, and Jiří Friml. “Auxin on the Road Navigated by Cellular PIN
Polarity.” Auxin and Its Role in Plant Development, edited by Eva Zažímalová
et al., Springer, 2014, pp. 143–70, doi:10.1007/978-3-7091-1526-8_8.
short: P. Baster, J. Friml, in:, E. Zažímalová, J. Petrášek, E. Benková (Eds.),
Auxin and Its Role in Plant Development, Springer, 2014, pp. 143–170.
date_created: 2018-12-11T11:54:07Z
date_published: 2014-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:19Z
day: '01'
department:
- _id: JiFr
doi: 10.1007/978-3-7091-1526-8_8
editor:
- first_name: Eva
full_name: Zažímalová, Eva
last_name: Zažímalová
- first_name: Jan
full_name: Petrášek, Jan
last_name: Petrášek
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
language:
- iso: eng
month: '04'
oa_version: None
page: 143 - 170
publication: Auxin and Its Role in Plant Development
publication_status: published
publisher: Springer
publist_id: '5304'
quality_controlled: '1'
scopus_import: 1
status: public
title: Auxin on the road navigated by cellular PIN polarity
type: book_chapter
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '2443'
abstract:
- lang: eng
text: The mode of action of auxin is based on its non-uniform distribution within
tissues and organs. Despite the wide use of several auxin analogues in research
and agriculture, little is known about the specificity of different auxin-related
transport and signalling processes towards these compounds. Using seedlings of
Arabidopsis thaliana and suspension-cultured cells of Nicotiana tabacum (BY-2),
the physiological activity of several auxin analogues was investigated, together
with their capacity to induce auxin-dependent gene expression, to inhibit endocytosis
and to be transported across the plasma membrane. This study shows that the specificity
criteria for different auxin-related processes vary widely. Notably, the special
behaviour of some synthetic auxin analogues suggests that they might be useful
tools in investigations of the molecular mechanism of auxin action. Thus, due
to their differential stimulatory effects on DR5 expression, indole-3-propionic
(IPA) and 2,4,5-trichlorophenoxy acetic (2,4,5-T) acids can serve in studies of
TRANSPORT INHIBITOR RESPONSE 1/AUXIN SIGNALLING F-BOX (TIR1/AFB)-mediated auxin
signalling, and 5-fluoroindole-3-acetic acid (5-F-IAA) can help to discriminate
between transcriptional and non-transcriptional pathways of auxin signalling.
The results demonstrate that the major determinants for the auxin-like physiological
potential of a particular compound are very complex and involve its chemical and
metabolic stability, its ability to distribute in tissues in a polar manner and
its activity towards auxin signalling machinery.
acknowledgement: The authors thank Dr Christian Luschnig (University of Natural Resources
and Life Sciences (BOKU), Vienna, Austria) for the anti-PIN2 antibody, Professor
Mark Estelle (University of California, San Diego, CA, USA) for tir1-1 mutant seeds
and, last but not least, to Dr David Morris for critical reading of the manuscript.
We also thank Markéta Pařezová and Jana Stýblová for excellent technical assistance.
This work was supported by the Grant Agency of the Czech Republic (P305/11/0797
to E.Z. and 13-40637S to J.F.), the Central European Institute of Technology project
CZ.1.05/1.1.00/02.0068 from the European Regional Development Fund and by a European
Research Council starting independent research grant ERC-2011-StG-20101109-PSDP
(to J.F.).
article_processing_charge: No
article_type: original
author:
- first_name: Sibu
full_name: Simon, Sibu
id: 4542EF9A-F248-11E8-B48F-1D18A9856A87
last_name: Simon
orcid: 0000-0002-1998-6741
- first_name: Martin
full_name: Kubeš, Martin
last_name: Kubeš
- first_name: Pawel
full_name: Baster, Pawel
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Petre
full_name: Dobrev, Petre
last_name: Dobrev
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Jan
full_name: Petrášek, Jan
last_name: Petrášek
- first_name: Eva
full_name: Zažímalová, Eva
last_name: Zažímalová
citation:
ama: 'Simon S, Kubeš M, Baster P, et al. Defining the selectivity of processes along
the auxin response chain: A study using auxin analogues. New Phytologist.
2013;200(4):1034-1048. doi:10.1111/nph.12437'
apa: 'Simon, S., Kubeš, M., Baster, P., Robert, S., Dobrev, P., Friml, J., … Zažímalová,
E. (2013). Defining the selectivity of processes along the auxin response chain:
A study using auxin analogues. New Phytologist. Wiley. https://doi.org/10.1111/nph.12437'
chicago: 'Simon, Sibu, Martin Kubeš, Pawel Baster, Stéphanie Robert, Petre Dobrev,
Jiří Friml, Jan Petrášek, and Eva Zažímalová. “Defining the Selectivity of Processes
along the Auxin Response Chain: A Study Using Auxin Analogues.” New Phytologist.
Wiley, 2013. https://doi.org/10.1111/nph.12437.'
ieee: 'S. Simon et al., “Defining the selectivity of processes along the
auxin response chain: A study using auxin analogues,” New Phytologist,
vol. 200, no. 4. Wiley, pp. 1034–1048, 2013.'
ista: 'Simon S, Kubeš M, Baster P, Robert S, Dobrev P, Friml J, Petrášek J, Zažímalová
E. 2013. Defining the selectivity of processes along the auxin response chain:
A study using auxin analogues. New Phytologist. 200(4), 1034–1048.'
mla: 'Simon, Sibu, et al. “Defining the Selectivity of Processes along the Auxin
Response Chain: A Study Using Auxin Analogues.” New Phytologist, vol. 200,
no. 4, Wiley, 2013, pp. 1034–48, doi:10.1111/nph.12437.'
short: S. Simon, M. Kubeš, P. Baster, S. Robert, P. Dobrev, J. Friml, J. Petrášek,
E. Zažímalová, New Phytologist 200 (2013) 1034–1048.
date_created: 2018-12-11T11:57:41Z
date_published: 2013-12-01T00:00:00Z
date_updated: 2025-05-07T11:12:32Z
day: '01'
department:
- _id: JiFr
doi: 10.1111/nph.12437
ec_funded: 1
intvolume: ' 200'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1111/nph.12437
month: '12'
oa: 1
oa_version: Published Version
page: 1034 - 1048
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: New Phytologist
publication_status: published
publisher: Wiley
publist_id: '4460'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Defining the selectivity of processes along the auxin response chain: A study
using auxin analogues'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 200
year: '2013'
...
---
_id: '2448'
abstract:
- lang: eng
text: Cell-to-cell directional flow of the phytohormone auxin is primarily established
by polar localization of the PIN auxin transporters, a process tightly regulated
at multiple levels by auxin itself. We recently reported that, in the context
of strong auxin flows, activity of the vacuolar ZIFL1.1 transporter is required
for fine-tuning of polar auxin transport rates in the Arabidopsis root. In particular,
ZIFL1.1 function protects plasma-membrane stability of the PIN2 carrier in epidermal
root tip cells under conditions normally triggering PIN2 degradation. Here, we
show that ZIFL1.1 activity at the root tip also promotes PIN1 plasma-membrane
abundance in central cylinder cells, thus supporting the notion that ZIFL1.1 acts
as a general positive modulator of polar auxin transport in roots.
article_number: e25688
article_processing_charge: No
article_type: original
author:
- first_name: Estelle
full_name: Remy, Estelle
last_name: Remy
- first_name: Pawel
full_name: Baster, Pawel
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Paula
full_name: Duque, Paula
last_name: Duque
citation:
ama: Remy E, Baster P, Friml J, Duque P. ZIFL1.1 transporter modulates polar auxin
transport by stabilizing membrane abundance of multiple PINs in Arabidopsis root
tip. Plant Signaling & Behavior. 2013;8(10). doi:10.4161/psb.25688
apa: Remy, E., Baster, P., Friml, J., & Duque, P. (2013). ZIFL1.1 transporter
modulates polar auxin transport by stabilizing membrane abundance of multiple
PINs in Arabidopsis root tip. Plant Signaling & Behavior. Taylor &
Francis. https://doi.org/10.4161/psb.25688
chicago: Remy, Estelle, Pawel Baster, Jiří Friml, and Paula Duque. “ZIFL1.1 Transporter
Modulates Polar Auxin Transport by Stabilizing Membrane Abundance of Multiple
PINs in Arabidopsis Root Tip.” Plant Signaling & Behavior. Taylor &
Francis, 2013. https://doi.org/10.4161/psb.25688.
ieee: E. Remy, P. Baster, J. Friml, and P. Duque, “ZIFL1.1 transporter modulates
polar auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis
root tip,” Plant Signaling & Behavior, vol. 8, no. 10. Taylor &
Francis, 2013.
ista: Remy E, Baster P, Friml J, Duque P. 2013. ZIFL1.1 transporter modulates polar
auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis
root tip. Plant Signaling & Behavior. 8(10), e25688.
mla: Remy, Estelle, et al. “ZIFL1.1 Transporter Modulates Polar Auxin Transport
by Stabilizing Membrane Abundance of Multiple PINs in Arabidopsis Root Tip.” Plant
Signaling & Behavior, vol. 8, no. 10, e25688, Taylor & Francis, 2013,
doi:10.4161/psb.25688.
short: E. Remy, P. Baster, J. Friml, P. Duque, Plant Signaling & Behavior 8
(2013).
date_created: 2018-12-11T11:57:43Z
date_published: 2013-07-10T00:00:00Z
date_updated: 2025-05-07T11:12:32Z
day: '10'
department:
- _id: JiFr
doi: 10.4161/psb.25688
ec_funded: 1
external_id:
pmid:
- '23857365'
intvolume: ' 8'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091088/
month: '07'
oa: 1
oa_version: Submitted Version
pmid: 1
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Plant Signaling & Behavior
publication_status: published
publisher: Taylor & Francis
publist_id: '4455'
quality_controlled: '1'
scopus_import: '1'
status: public
title: ZIFL1.1 transporter modulates polar auxin transport by stabilizing membrane
abundance of multiple PINs in Arabidopsis root tip
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2013'
...
---
_id: '2821'
abstract:
- lang: eng
text: Many key aspects of plant development are regulated by the polarized transport
of the phytohormone auxin. Cellular auxin efflux, the rate-limiting step in this
process, has been shown to rely on the coordinated action of PIN-formed (PIN)
and B-type ATP binding cassette (ABCB) carriers. Here, we report that polar auxin
transport in the Arabidopsis thaliana root also requires the action of a Major
Facilitator Superfamily (MFS) transporter, Zinc-Induced Facilitator-Like 1 (ZIFL1).
Sequencing, promoter-reporter, and fluorescent protein fusion experiments indicate
that the full-length ZIFL1.1 protein and a truncated splice isoform, ZIFL1.3,
localize to the tonoplast of root cells and the plasma membrane of leaf stomatal
guard cells, respectively. Using reverse genetics, we show that the ZIFL1.1 transporter
regulates various root auxin-related processes, while the ZIFL1.3 isoform mediates
drought tolerance by regulating stomatal closure. Auxin transport and immunolocalization
assays demonstrate that ZIFL1.1 indirectly modulates cellular auxin efflux during
shootward auxin transport at the root tip, likely by regulating plasma membrane
PIN2 abundance. Finally, heterologous expression in yeast revealed that ZIFL1.1
and ZIFL1.3 share H+-coupled K+ transport activity. Thus, by determining the subcellular
and tissue distribution of two isoforms, alternative splicing dictates a dual
function for the ZIFL1 transporter. We propose that this MFS carrier regulates
stomatal movements and polar auxin transport by modulating potassium and proton
fluxes in Arabidopsis cells.
author:
- first_name: Estelle
full_name: Remy, Estelle
last_name: Remy
- first_name: Tânia
full_name: Cabrito, Tânia
last_name: Cabrito
- first_name: Pawel
full_name: Baster, Pawel
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Rita
full_name: Batista, Rita
last_name: Batista
- first_name: Miguel
full_name: Teixeira, Miguel
last_name: Teixeira
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Isabel
full_name: Sá Correia, Isabel
last_name: Sá Correia
- first_name: Paula
full_name: Duque, Paula
last_name: Duque
citation:
ama: Remy E, Cabrito T, Baster P, et al. A major facilitator superfamily transporter
plays a dual role in polar auxin transport and drought stress tolerance in Arabidopsis.
Plant Cell. 2013;25(3):901-926. doi:10.1105/tpc.113.110353
apa: Remy, E., Cabrito, T., Baster, P., Batista, R., Teixeira, M., Friml, J., …
Duque, P. (2013). A major facilitator superfamily transporter plays a dual role
in polar auxin transport and drought stress tolerance in Arabidopsis. Plant
Cell. American Society of Plant Biologists. https://doi.org/10.1105/tpc.113.110353
chicago: Remy, Estelle, Tânia Cabrito, Pawel Baster, Rita Batista, Miguel Teixeira,
Jiří Friml, Isabel Sá Correia, and Paula Duque. “A Major Facilitator Superfamily
Transporter Plays a Dual Role in Polar Auxin Transport and Drought Stress Tolerance
in Arabidopsis.” Plant Cell. American Society of Plant Biologists, 2013.
https://doi.org/10.1105/tpc.113.110353.
ieee: E. Remy et al., “A major facilitator superfamily transporter plays
a dual role in polar auxin transport and drought stress tolerance in Arabidopsis,”
Plant Cell, vol. 25, no. 3. American Society of Plant Biologists, pp. 901–926,
2013.
ista: Remy E, Cabrito T, Baster P, Batista R, Teixeira M, Friml J, Sá Correia I,
Duque P. 2013. A major facilitator superfamily transporter plays a dual role in
polar auxin transport and drought stress tolerance in Arabidopsis. Plant Cell.
25(3), 901–926.
mla: Remy, Estelle, et al. “A Major Facilitator Superfamily Transporter Plays a
Dual Role in Polar Auxin Transport and Drought Stress Tolerance in Arabidopsis.”
Plant Cell, vol. 25, no. 3, American Society of Plant Biologists, 2013,
pp. 901–26, doi:10.1105/tpc.113.110353.
short: E. Remy, T. Cabrito, P. Baster, R. Batista, M. Teixeira, J. Friml, I. Sá
Correia, P. Duque, Plant Cell 25 (2013) 901–926.
date_created: 2018-12-11T11:59:46Z
date_published: 2013-04-24T00:00:00Z
date_updated: 2021-01-12T06:59:57Z
day: '24'
department:
- _id: JiFr
doi: 10.1105/tpc.113.110353
external_id:
pmid:
- '23524662'
intvolume: ' 25'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634696/
month: '04'
oa: 1
oa_version: Submitted Version
page: 901 - 926
pmid: 1
publication: Plant Cell
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3980'
quality_controlled: '1'
scopus_import: 1
status: public
title: A major facilitator superfamily transporter plays a dual role in polar auxin
transport and drought stress tolerance in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2013'
...
---
_id: '2919'
abstract:
- lang: eng
text: The distribution of the phytohormone auxin regulates many aspects of plant
development including growth response to gravity. Gravitropic root curvature involves
coordinated and asymmetric cell elongation between the lower and upper side of
the root, mediated by differential cellular auxin levels. The asymmetry in the
auxin distribution is established and maintained by a spatio-temporal regulation
of the PIN-FORMED (PIN) auxin transporter activity. We provide novel insights
into the complex regulation of PIN abundance and activity during root gravitropism.
We show that PIN2 turnover is differentially regulated on the upper and lower
side of gravistimulated roots by distinct but partially overlapping auxin feedback
mechanisms. In addition to regulating transcription and clathrin-mediated internalization,
auxin also controls PIN abundance at the plasma membrane by promoting their vacuolar
targeting and degradation. This effect of elevated auxin levels requires the activity
of SKP-Cullin-F-box TIR1/AFB (SCF TIR1/AFB)-dependent pathway. Importantly, also
suboptimal auxin levels mediate PIN degradation utilizing the same signalling
pathway. These feedback mechanisms are functionally important during gravitropic
response and ensure fine-tuning of auxin fluxes for maintaining as well as terminating
asymmetric growth.
author:
- first_name: Pawel
full_name: Baster, Pawel
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Jürgen
full_name: Kleine Vehn, Jürgen
last_name: Kleine Vehn
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Urszula
full_name: Kania, Urszula
id: 4AE5C486-F248-11E8-B48F-1D18A9856A87
last_name: Kania
- first_name: Wim
full_name: Grunewald, Wim
last_name: Grunewald
- first_name: Bert
full_name: De Rybel, Bert
last_name: De Rybel
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Baster P, Robert S, Kleine Vehn J, et al. SCF^TIR1 AFB-auxin signalling regulates
PIN vacuolar trafficking and auxin fluxes during root gravitropism. EMBO Journal.
2013;32(2):260-274. doi:10.1038/emboj.2012.310
apa: Baster, P., Robert, S., Kleine Vehn, J., Vanneste, S., Kania, U., Grunewald,
W., … Friml, J. (2013). SCF^TIR1 AFB-auxin signalling regulates PIN vacuolar trafficking
and auxin fluxes during root gravitropism. EMBO Journal. Wiley-Blackwell.
https://doi.org/10.1038/emboj.2012.310
chicago: Baster, Pawel, Stéphanie Robert, Jürgen Kleine Vehn, Steffen Vanneste,
Urszula Kania, Wim Grunewald, Bert De Rybel, Tom Beeckman, and Jiří Friml. “SCF^TIR1
AFB-Auxin Signalling Regulates PIN Vacuolar Trafficking and Auxin Fluxes during
Root Gravitropism.” EMBO Journal. Wiley-Blackwell, 2013. https://doi.org/10.1038/emboj.2012.310.
ieee: P. Baster et al., “SCF^TIR1 AFB-auxin signalling regulates PIN vacuolar
trafficking and auxin fluxes during root gravitropism,” EMBO Journal, vol.
32, no. 2. Wiley-Blackwell, pp. 260–274, 2013.
ista: Baster P, Robert S, Kleine Vehn J, Vanneste S, Kania U, Grunewald W, De Rybel
B, Beeckman T, Friml J. 2013. SCF^TIR1 AFB-auxin signalling regulates PIN vacuolar
trafficking and auxin fluxes during root gravitropism. EMBO Journal. 32(2), 260–274.
mla: Baster, Pawel, et al. “SCF^TIR1 AFB-Auxin Signalling Regulates PIN Vacuolar
Trafficking and Auxin Fluxes during Root Gravitropism.” EMBO Journal, vol.
32, no. 2, Wiley-Blackwell, 2013, pp. 260–74, doi:10.1038/emboj.2012.310.
short: P. Baster, S. Robert, J. Kleine Vehn, S. Vanneste, U. Kania, W. Grunewald,
B. De Rybel, T. Beeckman, J. Friml, EMBO Journal 32 (2013) 260–274.
date_created: 2018-12-11T12:00:20Z
date_published: 2013-01-23T00:00:00Z
date_updated: 2021-01-12T07:00:41Z
day: '23'
department:
- _id: JiFr
doi: 10.1038/emboj.2012.310
external_id:
pmid:
- '23211744'
intvolume: ' 32'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553380/
month: '01'
oa: 1
oa_version: Submitted Version
page: 260 - 274
pmid: 1
publication: EMBO Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3818'
quality_controlled: '1'
scopus_import: 1
status: public
title: SCF^TIR1 AFB-auxin signalling regulates PIN vacuolar trafficking and auxin
fluxes during root gravitropism
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2013'
...
---
_id: '3105'
abstract:
- lang: eng
text: Growth and development are coordinated by an array of intercellular communications.
Known plant signaling molecules include phytohormones and hormone peptides. Although
both classes can be implicated in the same developmental processes, little is
known about the interplay between phytohormone action and peptide signaling within
the cellular microenvironment. We show that genes coding for small secretory peptides,
designated GOLVEN (GLV), modulate the distribution of the phytohormone auxin.
The deregulation of the GLV function impairs the formation of auxin gradients
and alters the reorientation of shoots and roots after a gravity stimulus. Specifically,
the GLV signal modulates the trafficking dynamics of the auxin efflux carrier
PIN-FORMED2 involved in root tropic responses and meristem organization. Our work
links the local action of secretory peptides with phytohormone transport. Root
growth factor (RGF) or GOLVEN (GLV) secreted peptides have previously been implicated
in meristem regulation. Whitford et al. now show that RGF/GLV peptides induce
rapid relocalization of the auxin efflux regulator PIN2, regulate auxin gradients,
and modulate auxin-dependent root responses to specific stimuli.
author:
- first_name: Ryan
full_name: Whitford, Ryan
last_name: Whitford
- first_name: Ana
full_name: Fernandez, Ana
last_name: Fernandez
- first_name: Ricardo
full_name: Tejos, Ricardo
last_name: Tejos
- first_name: Amparo
full_name: Pérez, Amparo Cuéllar
last_name: Pérez
- first_name: Jürgen
full_name: Kleine-Vehn, Jürgen
last_name: Kleine Vehn
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Andrzej
full_name: Drozdzecki, Andrzej
last_name: Drozdzecki
- first_name: Johannes
full_name: Leitner, Johannes
last_name: Leitner
- first_name: Lindy
full_name: Abas, Lindy
last_name: Abas
- first_name: Maarten
full_name: Aerts, Maarten
last_name: Aerts
- first_name: Kurt
full_name: Hoogewijs, Kurt
last_name: Hoogewijs
- first_name: Pawel
full_name: Pawel Baster
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Ruth
full_name: De Groodt, Ruth
last_name: De Groodt
- first_name: Yao
full_name: Lin, Yao-Cheng
last_name: Lin
- first_name: Véronique
full_name: Storme, Véronique
last_name: Storme
- first_name: Yves
full_name: Van de Peer, Yves
last_name: Van De Peer
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Annemieke
full_name: Madder, Annemieke
last_name: Madder
- first_name: Bart
full_name: Devreese, Bart
last_name: Devreese
- first_name: Christian
full_name: Luschnig, Christian
last_name: Luschnig
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Pierre
full_name: Hilson, Pierre
last_name: Hilson
citation:
ama: Whitford R, Fernandez A, Tejos R, et al. GOLVEN secretory peptides regulate
auxin carrier turnover during plant gravitropic responses. Developmental Cell.
2012;22(3):678-685. doi:10.1016/j.devcel.2012.02.002
apa: Whitford, R., Fernandez, A., Tejos, R., Pérez, A., Kleine Vehn, J., Vanneste,
S., … Hilson, P. (2012). GOLVEN secretory peptides regulate auxin carrier turnover
during plant gravitropic responses. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2012.02.002
chicago: Whitford, Ryan, Ana Fernandez, Ricardo Tejos, Amparo Pérez, Jürgen Kleine
Vehn, Steffen Vanneste, Andrzej Drozdzecki, et al. “GOLVEN Secretory Peptides
Regulate Auxin Carrier Turnover during Plant Gravitropic Responses.” Developmental
Cell. Cell Press, 2012. https://doi.org/10.1016/j.devcel.2012.02.002.
ieee: R. Whitford et al., “GOLVEN secretory peptides regulate auxin carrier
turnover during plant gravitropic responses,” Developmental Cell, vol.
22, no. 3. Cell Press, pp. 678–685, 2012.
ista: Whitford R, Fernandez A, Tejos R, Pérez A, Kleine Vehn J, Vanneste S, Drozdzecki
A, Leitner J, Abas L, Aerts M, Hoogewijs K, Baster P, De Groodt R, Lin Y, Storme
V, Van De Peer Y, Beeckman T, Madder A, Devreese B, Luschnig C, Friml J, Hilson
P. 2012. GOLVEN secretory peptides regulate auxin carrier turnover during plant
gravitropic responses. Developmental Cell. 22(3), 678–685.
mla: Whitford, Ryan, et al. “GOLVEN Secretory Peptides Regulate Auxin Carrier Turnover
during Plant Gravitropic Responses.” Developmental Cell, vol. 22, no. 3,
Cell Press, 2012, pp. 678–85, doi:10.1016/j.devcel.2012.02.002.
short: R. Whitford, A. Fernandez, R. Tejos, A. Pérez, J. Kleine Vehn, S. Vanneste,
A. Drozdzecki, J. Leitner, L. Abas, M. Aerts, K. Hoogewijs, P. Baster, R. De Groodt,
Y. Lin, V. Storme, Y. Van De Peer, T. Beeckman, A. Madder, B. Devreese, C. Luschnig,
J. Friml, P. Hilson, Developmental Cell 22 (2012) 678–685.
date_created: 2018-12-11T12:01:25Z
date_published: 2012-03-13T00:00:00Z
date_updated: 2021-01-12T07:41:06Z
day: '13'
doi: 10.1016/j.devcel.2012.02.002
extern: 1
intvolume: ' 22'
issue: '3'
month: '03'
page: 678 - 685
publication: Developmental Cell
publication_status: published
publisher: Cell Press
publist_id: '3594'
quality_controlled: 0
status: public
title: GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic
responses
type: journal_article
volume: 22
year: '2012'
...
---
_id: '3075'
abstract:
- lang: eng
text: |2-
Spatial distribution of the plant hormone auxin regulates multiple aspects of plant development. These self-regulating auxin gradients are established by the action of PIN auxin transporters, whose activity is regulated by their constitutive cycling between the plasma membrane and endosomes. Here, we show that auxin signaling by the auxin receptor AUXIN-BINDING PROTEIN 1 (ABP1) inhibits the clathrin-mediated internalization of PIN proteins. ABP1 acts as a positive factor in clathrin recruitment to the plasma membrane, thereby promoting endocytosis. Auxin binding to ABP1 interferes with this action and leads to the inhibition of clathrin-mediated endocytosis. Our study demonstrates that ABP1 mediates a nontranscriptional auxin signaling that regulates the evolutionarily conserved process of clathrin-mediated endocytosis and suggests that this signaling may be essential for the developmentally important feedback of auxin on its own transport.
author:
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Jürgen
full_name: Kleine-Vehn, Jürgen
last_name: Kleine Vehn
- first_name: Elke
full_name: Barbez, Elke
last_name: Barbez
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Tomasz
full_name: Paciorek, Tomasz
last_name: Paciorek
- first_name: Pawel
full_name: Pawel Baster
id: 3028BD74-F248-11E8-B48F-1D18A9856A87
last_name: Baster
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Jing
full_name: Zhang, Jing
last_name: Zhang
- first_name: Sibu
full_name: Sibu Simon
id: 4542EF9A-F248-11E8-B48F-1D18A9856A87
last_name: Simon
orcid: 0000-0002-1998-6741
- first_name: Milada
full_name: Čovanová, Milada
last_name: Čovanová
- first_name: Kenichiro
full_name: Hayashi, Kenichiro
last_name: Hayashi
- first_name: Pankaj
full_name: Dhonukshe, Pankaj
last_name: Dhonukshe
- first_name: Zhenbiao
full_name: Yang, Zhenbiao
last_name: Yang
- first_name: Sebastian
full_name: Bednarek, Sebastian Y
last_name: Bednarek
- first_name: Alan
full_name: Jones, Alan M
last_name: Jones
- first_name: Christian
full_name: Luschnig, Christian
last_name: Luschnig
- first_name: Fernando
full_name: Aniento, Fernando
last_name: Aniento
- first_name: Eva
full_name: Zažímalová, Eva
last_name: Zažímalová
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Robert S, Kleine Vehn J, Barbez E, et al. ABP1 mediates auxin inhibition of
clathrin-dependent endocytosis in Arabidopsis. Cell. 2010;143(1):111-121.
doi:10.1016/j.cell.2010.09.027
apa: Robert, S., Kleine Vehn, J., Barbez, E., Sauer, M., Paciorek, T., Baster, P.,
… Friml, J. (2010). ABP1 mediates auxin inhibition of clathrin-dependent endocytosis
in Arabidopsis. Cell. Cell Press. https://doi.org/10.1016/j.cell.2010.09.027
chicago: Robert, Stéphanie, Jürgen Kleine Vehn, Elke Barbez, Michael Sauer, Tomasz
Paciorek, Pawel Baster, Steffen Vanneste, et al. “ABP1 Mediates Auxin Inhibition
of Clathrin-Dependent Endocytosis in Arabidopsis.” Cell. Cell Press, 2010.
https://doi.org/10.1016/j.cell.2010.09.027.
ieee: S. Robert et al., “ABP1 mediates auxin inhibition of clathrin-dependent
endocytosis in Arabidopsis,” Cell, vol. 143, no. 1. Cell Press, pp. 111–121,
2010.
ista: Robert S, Kleine Vehn J, Barbez E, Sauer M, Paciorek T, Baster P, Vanneste
S, Zhang J, Simon S, Čovanová M, Hayashi K, Dhonukshe P, Yang Z, Bednarek S, Jones
A, Luschnig C, Aniento F, Zažímalová E, Friml J. 2010. ABP1 mediates auxin inhibition
of clathrin-dependent endocytosis in Arabidopsis. Cell. 143(1), 111–121.
mla: Robert, Stéphanie, et al. “ABP1 Mediates Auxin Inhibition of Clathrin-Dependent
Endocytosis in Arabidopsis.” Cell, vol. 143, no. 1, Cell Press, 2010, pp.
111–21, doi:10.1016/j.cell.2010.09.027.
short: S. Robert, J. Kleine Vehn, E. Barbez, M. Sauer, T. Paciorek, P. Baster, S.
Vanneste, J. Zhang, S. Simon, M. Čovanová, K. Hayashi, P. Dhonukshe, Z. Yang,
S. Bednarek, A. Jones, C. Luschnig, F. Aniento, E. Zažímalová, J. Friml, Cell
143 (2010) 111–121.
date_created: 2018-12-11T12:01:13Z
date_published: 2010-10-01T00:00:00Z
date_updated: 2021-01-12T07:40:52Z
day: '01'
doi: 10.1016/j.cell.2010.09.027
extern: 1
intvolume: ' 143'
issue: '1'
month: '10'
page: 111 - 121
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '3626'
quality_controlled: 0
status: public
title: ABP1 mediates auxin inhibition of clathrin-dependent endocytosis in Arabidopsis
type: journal_article
volume: 143
year: '2010'
...