---
_id: '14754'
abstract:
- lang: eng
  text: The large-scale laminar/turbulent spiral patterns that appear in the linearly
    unstable regime of counter-rotating Taylor–Couette flow are investigated from
    a statistical perspective by means of direct numerical simulation. Unlike the
    vast majority of previous numerical studies, we analyse the flow in periodic parallelogram-annular
    domains, following a coordinate change that aligns one of the parallelogram sides
    with the spiral pattern. The domain size, shape and spatial resolution have been
    varied and the results compared with those in a sufficiently large computational
    orthogonal domain with natural axial and azimuthal periodicity. We find that a
    minimal parallelogram of the right tilt significantly reduces the computational
    cost without notably compromising the statistical properties of the supercritical
    turbulent spiral. Its mean structure, obtained from extremely long time integrations
    in a co-rotating reference frame using the method of slices, bears remarkable
    similarity with the turbulent stripes observed in plane Couette flow, the centrifugal
    instability playing only a secondary role.
acknowledgement: K.D.’s research was supported by Australian Research Council Discovery
  Early Career Researcher Award (DE170100171). B.W., R.A., F.M. and A.M. research
  was supported by the Spanish Ministerio de Economía y Competitividad (grant nos.
  FIS2016-77849-R and FIS2017-85794-P) and Ministerio de Ciencia e Innovación (grant
  no. PID2020-114043GB-I00) and the Generalitat de Catalunya (grant no. 2017-SGR-785).
  B.W.’s research was also supported by the Chinese Scholarship Council (grant CSC
  no. 201806440152). F.M. is a Serra-Húnter Fellow.
article_number: '0112'
article_processing_charge: No
article_type: original
author:
- first_name: B.
  full_name: Wang, B.
  last_name: Wang
- first_name: F.
  full_name: Mellibovsky, F.
  last_name: Mellibovsky
- first_name: Roger
  full_name: Ayats López, Roger
  id: ab77522d-073b-11ed-8aff-e71b39258362
  last_name: Ayats López
  orcid: 0000-0001-6572-0621
- first_name: K.
  full_name: Deguchi, K.
  last_name: Deguchi
- first_name: A.
  full_name: Meseguer, A.
  last_name: Meseguer
citation:
  ama: Wang B, Mellibovsky F, Ayats López R, Deguchi K, Meseguer A. Mean structure
    of the supercritical turbulent spiral in Taylor–Couette flow. <i>Philosophical
    Transactions of the Royal Society A</i>. 2023;381(2246). doi:<a href="https://doi.org/10.1098/rsta.2022.0112">10.1098/rsta.2022.0112</a>
  apa: Wang, B., Mellibovsky, F., Ayats López, R., Deguchi, K., &#38; Meseguer, A.
    (2023). Mean structure of the supercritical turbulent spiral in Taylor–Couette
    flow. <i>Philosophical Transactions of the Royal Society A</i>. The Royal Society.
    <a href="https://doi.org/10.1098/rsta.2022.0112">https://doi.org/10.1098/rsta.2022.0112</a>
  chicago: Wang, B., F. Mellibovsky, Roger Ayats López, K. Deguchi, and A. Meseguer.
    “Mean Structure of the Supercritical Turbulent Spiral in Taylor–Couette Flow.”
    <i>Philosophical Transactions of the Royal Society A</i>. The Royal Society, 2023.
    <a href="https://doi.org/10.1098/rsta.2022.0112">https://doi.org/10.1098/rsta.2022.0112</a>.
  ieee: B. Wang, F. Mellibovsky, R. Ayats López, K. Deguchi, and A. Meseguer, “Mean
    structure of the supercritical turbulent spiral in Taylor–Couette flow,” <i>Philosophical
    Transactions of the Royal Society A</i>, vol. 381, no. 2246. The Royal Society,
    2023.
  ista: Wang B, Mellibovsky F, Ayats López R, Deguchi K, Meseguer A. 2023. Mean structure
    of the supercritical turbulent spiral in Taylor–Couette flow. Philosophical Transactions
    of the Royal Society A. 381(2246), 0112.
  mla: Wang, B., et al. “Mean Structure of the Supercritical Turbulent Spiral in Taylor–Couette
    Flow.” <i>Philosophical Transactions of the Royal Society A</i>, vol. 381, no.
    2246, 0112, The Royal Society, 2023, doi:<a href="https://doi.org/10.1098/rsta.2022.0112">10.1098/rsta.2022.0112</a>.
  short: B. Wang, F. Mellibovsky, R. Ayats López, K. Deguchi, A. Meseguer, Philosophical
    Transactions of the Royal Society A 381 (2023).
date_created: 2024-01-08T13:11:45Z
date_published: 2023-05-01T00:00:00Z
date_updated: 2024-01-09T09:15:29Z
day: '01'
ddc:
- '530'
department:
- _id: BjHo
doi: 10.1098/rsta.2022.0112
external_id:
  pmid:
  - '36907214'
file:
- access_level: open_access
  checksum: 1978d126c0ce2f47c22ac20107cc0106
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-09T09:13:53Z
  date_updated: 2024-01-09T09:13:53Z
  file_id: '14763'
  file_name: 2023_PhilTransactionsA_Wang_accepted.pdf
  file_size: 6421086
  relation: main_file
  success: 1
file_date_updated: 2024-01-09T09:13:53Z
has_accepted_license: '1'
intvolume: '       381'
issue: '2246'
keyword:
- General Physics and Astronomy
- General Engineering
- General Mathematics
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '05'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Philosophical Transactions of the Royal Society A
publication_identifier:
  eissn:
  - 1471-2962
  issn:
  - 1364-503X
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mean structure of the supercritical turbulent spiral in Taylor–Couette flow
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 381
year: '2023'
...
---
_id: '14755'
abstract:
- lang: eng
  text: We consider the sharp interface limit for the scalar-valued and vector-valued
    Allen–Cahn equation with homogeneous Neumann boundary condition in a bounded smooth
    domain Ω of arbitrary dimension N ⩾ 2 in the situation when a two-phase diffuse
    interface has developed and intersects the boundary ∂ Ω. The limit problem is
    mean curvature flow with 90°-contact angle and we show convergence in strong norms
    for well-prepared initial data as long as a smooth solution to the limit problem
    exists. To this end we assume that the limit problem has a smooth solution on
    [ 0 , T ] for some time T &gt; 0. Based on the latter we construct suitable curvilinear
    coordinates and set up an asymptotic expansion for the scalar-valued and the vector-valued
    Allen–Cahn equation. In order to estimate the difference of the exact and approximate
    solutions with a Gronwall-type argument, a spectral estimate for the linearized
    Allen–Cahn operator in both cases is required. The latter will be shown in a separate
    paper, cf. (Moser (2021)).
acknowledgement: "The author gratefully acknowledges support through DFG, GRK 1692
  “Curvature,\r\nCycles and Cohomology” during parts of the work."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Maximilian
  full_name: Moser, Maximilian
  id: a60047a9-da77-11eb-85b4-c4dc385ebb8c
  last_name: Moser
citation:
  ama: 'Moser M. Convergence of the scalar- and vector-valued Allen–Cahn equation
    to mean curvature flow with 90°-contact angle in higher dimensions, part I: Convergence
    result. <i>Asymptotic Analysis</i>. 2023;131(3-4):297-383. doi:<a href="https://doi.org/10.3233/asy-221775">10.3233/asy-221775</a>'
  apa: 'Moser, M. (2023). Convergence of the scalar- and vector-valued Allen–Cahn
    equation to mean curvature flow with 90°-contact angle in higher dimensions, part
    I: Convergence result. <i>Asymptotic Analysis</i>. IOS Press. <a href="https://doi.org/10.3233/asy-221775">https://doi.org/10.3233/asy-221775</a>'
  chicago: 'Moser, Maximilian. “Convergence of the Scalar- and Vector-Valued Allen–Cahn
    Equation to Mean Curvature Flow with 90°-Contact Angle in Higher Dimensions, Part
    I: Convergence Result.” <i>Asymptotic Analysis</i>. IOS Press, 2023. <a href="https://doi.org/10.3233/asy-221775">https://doi.org/10.3233/asy-221775</a>.'
  ieee: 'M. Moser, “Convergence of the scalar- and vector-valued Allen–Cahn equation
    to mean curvature flow with 90°-contact angle in higher dimensions, part I: Convergence
    result,” <i>Asymptotic Analysis</i>, vol. 131, no. 3–4. IOS Press, pp. 297–383,
    2023.'
  ista: 'Moser M. 2023. Convergence of the scalar- and vector-valued Allen–Cahn equation
    to mean curvature flow with 90°-contact angle in higher dimensions, part I: Convergence
    result. Asymptotic Analysis. 131(3–4), 297–383.'
  mla: 'Moser, Maximilian. “Convergence of the Scalar- and Vector-Valued Allen–Cahn
    Equation to Mean Curvature Flow with 90°-Contact Angle in Higher Dimensions, Part
    I: Convergence Result.” <i>Asymptotic Analysis</i>, vol. 131, no. 3–4, IOS Press,
    2023, pp. 297–383, doi:<a href="https://doi.org/10.3233/asy-221775">10.3233/asy-221775</a>.'
  short: M. Moser, Asymptotic Analysis 131 (2023) 297–383.
date_created: 2024-01-08T13:13:28Z
date_published: 2023-02-02T00:00:00Z
date_updated: 2024-01-09T09:22:16Z
day: '02'
department:
- _id: JuFi
doi: 10.3233/asy-221775
external_id:
  arxiv:
  - '2105.07100'
intvolume: '       131'
issue: 3-4
keyword:
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2105.07100
month: '02'
oa: 1
oa_version: Preprint
page: 297-383
publication: Asymptotic Analysis
publication_identifier:
  eissn:
  - 1875-8576
  issn:
  - 0921-7134
publication_status: published
publisher: IOS Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Convergence of the scalar- and vector-valued Allen–Cahn equation to mean curvature
  flow with 90°-contact angle in higher dimensions, part I: Convergence result'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 131
year: '2023'
...
---
_id: '14756'
abstract:
- lang: eng
  text: "We prove the r-spin cobordism hypothesis in the setting of (weak) 2-categories
    for every positive integer r: the 2-groupoid of 2-dimensional fully extended r-spin
    TQFTs with given target is equivalent to the homotopy fixed points of an induced
    Spin 2r -action. In particular, such TQFTs are classified by fully dualisable
    objects together with a trivialisation of the rth power of their Serre automorphisms.
    For r=1, we recover the oriented case (on which our proof builds), while ordinary
    spin structures correspond to r=2.\r\nTo construct examples, we explicitly describe
    Spin 2r​-homotopy fixed points in the equivariant completion of any symmetric
    monoidal 2-category. We also show that every object in a 2-category of Landau–Ginzburg
    models gives rise to fully extended spin TQFTs and that half of these do not factor
    through the oriented bordism 2-category."
acknowledgement: "N.C. is supported by the DFG Heisenberg Programme.\r\nWe are grateful
  to Tobias Dyckerhoff, Lukas Müller, Ingo Runkel, and Christopher Schommer-Pries
  for helpful discussions."
article_processing_charge: Yes
article_type: original
author:
- first_name: Nils
  full_name: Carqueville, Nils
  last_name: Carqueville
- first_name: Lorant
  full_name: Szegedy, Lorant
  id: 7943226E-220E-11EA-94C7-D59F3DDC885E
  last_name: Szegedy
  orcid: 0000-0003-2834-5054
citation:
  ama: Carqueville N, Szegedy L. Fully extended r-spin TQFTs. <i>Quantum Topology</i>.
    2023;14(3):467-532. doi:<a href="https://doi.org/10.4171/qt/193">10.4171/qt/193</a>
  apa: Carqueville, N., &#38; Szegedy, L. (2023). Fully extended r-spin TQFTs. <i>Quantum
    Topology</i>. European Mathematical Society. <a href="https://doi.org/10.4171/qt/193">https://doi.org/10.4171/qt/193</a>
  chicago: Carqueville, Nils, and Lorant Szegedy. “Fully Extended R-Spin TQFTs.” <i>Quantum
    Topology</i>. European Mathematical Society, 2023. <a href="https://doi.org/10.4171/qt/193">https://doi.org/10.4171/qt/193</a>.
  ieee: N. Carqueville and L. Szegedy, “Fully extended r-spin TQFTs,” <i>Quantum Topology</i>,
    vol. 14, no. 3. European Mathematical Society, pp. 467–532, 2023.
  ista: Carqueville N, Szegedy L. 2023. Fully extended r-spin TQFTs. Quantum Topology.
    14(3), 467–532.
  mla: Carqueville, Nils, and Lorant Szegedy. “Fully Extended R-Spin TQFTs.” <i>Quantum
    Topology</i>, vol. 14, no. 3, European Mathematical Society, 2023, pp. 467–532,
    doi:<a href="https://doi.org/10.4171/qt/193">10.4171/qt/193</a>.
  short: N. Carqueville, L. Szegedy, Quantum Topology 14 (2023) 467–532.
date_created: 2024-01-08T13:14:48Z
date_published: 2023-10-16T00:00:00Z
date_updated: 2024-01-09T09:27:46Z
day: '16'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.4171/qt/193
file:
- access_level: open_access
  checksum: b0590aff6e7ec89cc149ba94d459d3a3
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-09T09:25:34Z
  date_updated: 2024-01-09T09:25:34Z
  file_id: '14764'
  file_name: 2023_QuantumTopol_Carqueville.pdf
  file_size: 707344
  relation: main_file
  success: 1
file_date_updated: 2024-01-09T09:25:34Z
has_accepted_license: '1'
intvolume: '        14'
issue: '3'
keyword:
- Geometry and Topology
- Mathematical Physics
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 467-532
publication: Quantum Topology
publication_identifier:
  issn:
  - 1663-487X
publication_status: published
publisher: European Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fully extended r-spin TQFTs
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2023'
...
---
_id: '14758'
abstract:
- lang: eng
  text: 'We present a flexible and efficient toolchain to symbolically solve (standard)
    Rabin games, fair-adversarial Rabin games, and 2 1/2 license type-player Rabin
    games. To our best knowledge, our tools are the first ones to be able to solve
    these problems. Furthermore, using these flexible game solvers as a back-end,
    we implemented a tool for computing correct-by-construction controllers for stochastic
    dynamical systems under LTL specifications. Our implementations use the recent
    theoretical result that all of these games can be solved using the same symbolic
    fixpoint algorithm but utilizing different, domain specific calculations of the
    involved predecessor operators. The main feature of our toolchain is the utilization
    of two programming abstractions: one to separate the symbolic fixpoint computations
    from the predecessor calculations, and another one to allow the integration of
    different BDD libraries as back-ends. In particular, we employ a multi-threaded
    execution of the fixpoint algorithm by using the multi-threaded BDD library Sylvan,
    which leads to enormous computational savings.'
acknowledgement: 'Authors ordered alphabetically. R. Majumdar and A.-K. Schmuck are
  partially supported by DFG project 389792660 TRR 248-CPEC. A.-K. Schmuck is additionally
  funded through DFG project (SCHM 3541/1-1). K. Mallik is supported by the ERC project
  ERC-2020-AdG 101020093. M. Rychlicki is supported by the EPSRC project EP/V00252X/1.
  S. Soudjani is supported by the following projects: EPSRC EP/V043676/1, EIC 101070802,
  and ERC 101089047.'
alternative_title:
- LNCS
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Rupak
  full_name: Majumdar, Rupak
  last_name: Majumdar
- first_name: Kaushik
  full_name: Mallik, Kaushik
  id: 0834ff3c-6d72-11ec-94e0-b5b0a4fb8598
  last_name: Mallik
  orcid: 0000-0001-9864-7475
- first_name: Mateusz
  full_name: Rychlicki, Mateusz
  last_name: Rychlicki
- first_name: Anne-Kathrin
  full_name: Schmuck, Anne-Kathrin
  last_name: Schmuck
- first_name: Sadegh
  full_name: Soudjani, Sadegh
  last_name: Soudjani
citation:
  ama: 'Majumdar R, Mallik K, Rychlicki M, Schmuck A-K, Soudjani S. A flexible toolchain
    for symbolic rabin games under fair and stochastic uncertainties. In: <i>35th
    International Conference on Computer Aided Verification</i>. Vol 13966. Springer
    Nature; 2023:3-15. doi:<a href="https://doi.org/10.1007/978-3-031-37709-9_1">10.1007/978-3-031-37709-9_1</a>'
  apa: 'Majumdar, R., Mallik, K., Rychlicki, M., Schmuck, A.-K., &#38; Soudjani, S.
    (2023). A flexible toolchain for symbolic rabin games under fair and stochastic
    uncertainties. In <i>35th International Conference on Computer Aided Verification</i>
    (Vol. 13966, pp. 3–15). Paris, France: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-37709-9_1">https://doi.org/10.1007/978-3-031-37709-9_1</a>'
  chicago: Majumdar, Rupak, Kaushik Mallik, Mateusz Rychlicki, Anne-Kathrin Schmuck,
    and Sadegh Soudjani. “A Flexible Toolchain for Symbolic Rabin Games under Fair
    and Stochastic Uncertainties.” In <i>35th International Conference on Computer
    Aided Verification</i>, 13966:3–15. Springer Nature, 2023. <a href="https://doi.org/10.1007/978-3-031-37709-9_1">https://doi.org/10.1007/978-3-031-37709-9_1</a>.
  ieee: R. Majumdar, K. Mallik, M. Rychlicki, A.-K. Schmuck, and S. Soudjani, “A flexible
    toolchain for symbolic rabin games under fair and stochastic uncertainties,” in
    <i>35th International Conference on Computer Aided Verification</i>, Paris, France,
    2023, vol. 13966, pp. 3–15.
  ista: 'Majumdar R, Mallik K, Rychlicki M, Schmuck A-K, Soudjani S. 2023. A flexible
    toolchain for symbolic rabin games under fair and stochastic uncertainties. 35th
    International Conference on Computer Aided Verification. CAV: Computer Aided Verification,
    LNCS, vol. 13966, 3–15.'
  mla: Majumdar, Rupak, et al. “A Flexible Toolchain for Symbolic Rabin Games under
    Fair and Stochastic Uncertainties.” <i>35th International Conference on Computer
    Aided Verification</i>, vol. 13966, Springer Nature, 2023, pp. 3–15, doi:<a href="https://doi.org/10.1007/978-3-031-37709-9_1">10.1007/978-3-031-37709-9_1</a>.
  short: R. Majumdar, K. Mallik, M. Rychlicki, A.-K. Schmuck, S. Soudjani, in:, 35th
    International Conference on Computer Aided Verification, Springer Nature, 2023,
    pp. 3–15.
conference:
  end_date: 2023-07-22
  location: Paris, France
  name: 'CAV: Computer Aided Verification'
  start_date: 2023-07-17
date_created: 2024-01-08T13:18:00Z
date_published: 2023-07-16T00:00:00Z
date_updated: 2024-02-27T07:39:51Z
day: '16'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/978-3-031-37709-9_1
ec_funded: 1
file:
- access_level: open_access
  checksum: 1a361d83db0244fd32c03b544c294b5a
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-09T10:01:07Z
  date_updated: 2024-01-09T10:01:07Z
  file_id: '14765'
  file_name: 2023_LNCSCAV_Majumdar.pdf
  file_size: 405147
  relation: main_file
  success: 1
file_date_updated: 2024-01-09T10:01:07Z
has_accepted_license: '1'
intvolume: '     13966'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 3-15
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 35th International Conference on Computer Aided Verification
publication_identifier:
  eisbn:
  - '9783031377099'
  eissn:
  - 1611-3349
  isbn:
  - '9783031377082'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '14994'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: A flexible toolchain for symbolic rabin games under fair and stochastic uncertainties
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13966
year: '2023'
...
---
_id: '14759'
abstract:
- lang: eng
  text: "Proper operation of electro-optic I/Q modulators relies on precise adjustment
    and control of the relative phase biases between the modulator’s internal interferometer
    arms. We present an all-analog phase bias locking scheme where error signals are
    obtained from the beat between the optical carrier and optical tones generated
    by an auxiliary 2 MHz \U0001D445\U0001D439 tone to lock the phases of all three
    involved interferometers for operation up to 10 GHz. With the developed method,
    we demonstrate an I/Q modulator in carrier-suppressed single-sideband mode, where
    the suppressed carrier and sideband are locked at optical power levels <−27dB\r\n
    relative to the transmitted sideband. We describe a simple analytical model for
    calculating the error signals and detail the implementation of the electronic
    circuitry for the implementation of the method."
acknowledgement: We thank Jakob Vorlaufer for technical contributions and Vyacheslav
  Li and Sofia Agafonova for comments on the manuscript.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sebastian
  full_name: Wald, Sebastian
  id: 133F200A-B015-11E9-AD41-0EDAE5697425
  last_name: Wald
  orcid: 0000-0002-5869-1604
- first_name: Fritz R
  full_name: Diorico, Fritz R
  id: 2E054C4C-F248-11E8-B48F-1D18A9856A87
  last_name: Diorico
  orcid: 0000-0002-4947-8924
- first_name: Onur
  full_name: Hosten, Onur
  id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
  last_name: Hosten
  orcid: 0000-0002-2031-204X
citation:
  ama: Wald S, Diorico FR, Hosten O. Analog stabilization of an electro-optic I/Q
    modulator with an auxiliary modulation tone. <i>Applied Optics</i>. 2023;62(1):1-7.
    doi:<a href="https://doi.org/10.1364/ao.474118">10.1364/ao.474118</a>
  apa: Wald, S., Diorico, F. R., &#38; Hosten, O. (2023). Analog stabilization of
    an electro-optic I/Q modulator with an auxiliary modulation tone. <i>Applied Optics</i>.
    Optica Publishing Group. <a href="https://doi.org/10.1364/ao.474118">https://doi.org/10.1364/ao.474118</a>
  chicago: Wald, Sebastian, Fritz R Diorico, and Onur Hosten. “Analog Stabilization
    of an Electro-Optic I/Q Modulator with an Auxiliary Modulation Tone.” <i>Applied
    Optics</i>. Optica Publishing Group, 2023. <a href="https://doi.org/10.1364/ao.474118">https://doi.org/10.1364/ao.474118</a>.
  ieee: S. Wald, F. R. Diorico, and O. Hosten, “Analog stabilization of an electro-optic
    I/Q modulator with an auxiliary modulation tone,” <i>Applied Optics</i>, vol.
    62, no. 1. Optica Publishing Group, pp. 1–7, 2023.
  ista: Wald S, Diorico FR, Hosten O. 2023. Analog stabilization of an electro-optic
    I/Q modulator with an auxiliary modulation tone. Applied Optics. 62(1), 1–7.
  mla: Wald, Sebastian, et al. “Analog Stabilization of an Electro-Optic I/Q Modulator
    with an Auxiliary Modulation Tone.” <i>Applied Optics</i>, vol. 62, no. 1, Optica
    Publishing Group, 2023, pp. 1–7, doi:<a href="https://doi.org/10.1364/ao.474118">10.1364/ao.474118</a>.
  short: S. Wald, F.R. Diorico, O. Hosten, Applied Optics 62 (2023) 1–7.
date_created: 2024-01-08T13:19:14Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2024-01-09T10:10:34Z
day: '01'
department:
- _id: OnHo
doi: 10.1364/ao.474118
external_id:
  arxiv:
  - '2208.11591'
intvolume: '        62'
issue: '1'
keyword:
- Atomic and Molecular Physics
- and Optics
- Engineering (miscellaneous)
- Electrical and Electronic Engineering
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2208.11591
month: '01'
oa: 1
oa_version: Preprint
page: 1-7
publication: Applied Optics
publication_identifier:
  eissn:
  - 2155-3165
  issn:
  - 1559-128X
publication_status: published
publisher: Optica Publishing Group
quality_controlled: '1'
scopus_import: '1'
status: public
title: Analog stabilization of an electro-optic I/Q modulator with an auxiliary modulation
  tone
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 62
year: '2023'
...
---
_id: '14768'
abstract:
- lang: eng
  text: 'In all state-of-the-art sketching and coreset techniques for clustering,
    as well as in the best known fixed-parameter tractable approximation algorithms,
    randomness plays a key role. For the classic k-median and k-means problems, there
    are no known deterministic dimensionality reduction procedure or coreset construction
    that avoid an exponential dependency on the input dimension d, the precision parameter
    $\varepsilon^{-1}$ or k. Furthermore, there is no coreset construction that succeeds
    with probability $1-1/n$ and whose size does not depend on the number of input
    points, n. This has led researchers in the area to ask what is the power of randomness
    for clustering sketches [Feldman WIREs Data Mining Knowl. Discov’20].Similarly,
    the best approximation ratio achievable deterministically without a complexity
    exponential in the dimension are $1+\sqrt{2}$ for k-median [Cohen-Addad, Esfandiari,
    Mirrokni, Narayanan, STOC’22] and 6.12903 for k-means [Grandoni, Ostrovsky, Rabani,
    Schulman, Venkat, Inf. Process. Lett.’22]. Those are the best results, even when
    allowing a complexity FPT in the number of clusters k: this stands in sharp contrast
    with the $(1+\varepsilon)$-approximation achievable in that case, when allowing
    randomization.In this paper, we provide deterministic sketches constructions for
    clustering, whose size bounds are close to the best-known randomized ones. We
    show how to compute a dimension reduction onto $\varepsilon^{-O(1)} \log k$ dimensions
    in time $k^{O\left(\varepsilon^{-O(1)}+\log \log k\right)}$ poly $(n d)$, and
    how to build a coreset of size $O\left(k^{2} \log ^{3} k \varepsilon^{-O(1)}\right)$
    in time $2^{\varepsilon^{O(1)} k \log ^{3} k}+k^{O\left(\varepsilon^{-O(1)}+\log
    \log k\right)}$ poly $(n d)$. In the case where k is small, this answers an open
    question of [Feldman WIDM’20] and [Munteanu and Schwiegelshohn, Künstliche Intell.
    ’18] on whether it is possible to efficiently compute coresets deterministically.We
    also construct a deterministic algorithm for computing $(1+$ $\varepsilon)$-approximation
    to k-median and k-means in high dimensional Euclidean spaces in time $2^{k^{2}
    \log ^{3} k / \varepsilon^{O(1)}}$ poly $(n d)$, close to the best randomized
    complexity of $2^{(k / \varepsilon)^{O(1)}}$ nd (see [Kumar, Sabharwal, Sen, JACM
    10] and [Bhattacharya, Jaiswal, Kumar, TCS’18]).Furthermore, our new insights
    on sketches also yield a randomized coreset construction that uses uniform sampling,
    that immediately improves over the recent results of [Braverman et al. FOCS ’22]
    by a factor k.'
acknowledgement: "D. Sauplic has received funding from the European Union’s Horizon
  2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement
  No 101034413, and Grant agreement No. 101019564 “The Design of Modern Fully Dynamic
  Data Structures (MoDynStruct)”.\r\nC. Schwiegelshohn acknowledges the support of
  the Independent Research Fund Denmark (DFF) under a Sapere Aude Research Leader
  grant No 1051-00106B."
article_processing_charge: No
arxiv: 1
author:
- first_name: Vincent
  full_name: Cohen-Addad, Vincent
  last_name: Cohen-Addad
- first_name: David
  full_name: Saulpic, David
  id: f8e48cf0-b0ff-11ed-b0e9-b4c35598f964
  last_name: Saulpic
- first_name: Chris
  full_name: Schwiegelshohn, Chris
  last_name: Schwiegelshohn
citation:
  ama: 'Cohen-Addad V, Saulpic D, Schwiegelshohn C. Deterministic clustering in high
    dimensional spaces: Sketches and approximation. In: <i>2023 IEEE 64th Annual Symposium
    on Foundations of Computer Science</i>. IEEE; 2023:1105-1130. doi:<a href="https://doi.org/10.1109/focs57990.2023.00066">10.1109/focs57990.2023.00066</a>'
  apa: 'Cohen-Addad, V., Saulpic, D., &#38; Schwiegelshohn, C. (2023). Deterministic
    clustering in high dimensional spaces: Sketches and approximation. In <i>2023
    IEEE 64th Annual Symposium on Foundations of Computer Science</i> (pp. 1105–1130).
    Santa Cruz, CA, United States: IEEE. <a href="https://doi.org/10.1109/focs57990.2023.00066">https://doi.org/10.1109/focs57990.2023.00066</a>'
  chicago: 'Cohen-Addad, Vincent, David Saulpic, and Chris Schwiegelshohn. “Deterministic
    Clustering in High Dimensional Spaces: Sketches and Approximation.” In <i>2023
    IEEE 64th Annual Symposium on Foundations of Computer Science</i>, 1105–30. IEEE,
    2023. <a href="https://doi.org/10.1109/focs57990.2023.00066">https://doi.org/10.1109/focs57990.2023.00066</a>.'
  ieee: 'V. Cohen-Addad, D. Saulpic, and C. Schwiegelshohn, “Deterministic clustering
    in high dimensional spaces: Sketches and approximation,” in <i>2023 IEEE 64th
    Annual Symposium on Foundations of Computer Science</i>, Santa Cruz, CA, United
    States, 2023, pp. 1105–1130.'
  ista: 'Cohen-Addad V, Saulpic D, Schwiegelshohn C. 2023. Deterministic clustering
    in high dimensional spaces: Sketches and approximation. 2023 IEEE 64th Annual
    Symposium on Foundations of Computer Science. FOCS: Symposium on Foundations of
    Computer Science, 1105–1130.'
  mla: 'Cohen-Addad, Vincent, et al. “Deterministic Clustering in High Dimensional
    Spaces: Sketches and Approximation.” <i>2023 IEEE 64th Annual Symposium on Foundations
    of Computer Science</i>, IEEE, 2023, pp. 1105–30, doi:<a href="https://doi.org/10.1109/focs57990.2023.00066">10.1109/focs57990.2023.00066</a>.'
  short: V. Cohen-Addad, D. Saulpic, C. Schwiegelshohn, in:, 2023 IEEE 64th Annual
    Symposium on Foundations of Computer Science, IEEE, 2023, pp. 1105–1130.
conference:
  end_date: 2023-11-09
  location: Santa Cruz, CA, United States
  name: 'FOCS: Symposium on Foundations of Computer Science'
  start_date: 2023-11-06
date_created: 2024-01-09T16:20:09Z
date_published: 2023-12-22T00:00:00Z
date_updated: 2024-01-16T07:28:06Z
day: '22'
department:
- _id: MoHe
doi: 10.1109/focs57990.2023.00066
ec_funded: 1
external_id:
  arxiv:
  - '2310.04076'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2310.04076
month: '12'
oa: 1
oa_version: Preprint
page: 1105-1130
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
  call_identifier: H2020
  grant_number: '101019564'
  name: The design and evaluation of modern fully dynamic data structures
publication: 2023 IEEE 64th Annual Symposium on Foundations of Computer Science
publication_identifier:
  eisbn:
  - '9798350318944'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Deterministic clustering in high dimensional spaces: Sketches and approximation'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2023'
...
---
_id: '14771'
abstract:
- lang: eng
  text: Pruning—that is, setting a significant subset of the parameters of a neural
    network to zero—is one of the most popular methods of model compression. Yet,
    several recent works have raised the issue that pruning may induce or exacerbate
    bias in the output of the compressed model. Despite existing evidence for this
    phenomenon, the relationship between neural network pruning and induced bias is
    not well-understood. In this work, we systematically investigate and characterize
    this phenomenon in Convolutional Neural Networks for computer vision. First, we
    show that it is in fact possible to obtain highly-sparse models, e.g. with less
    than 10% remaining weights, which do not decrease in accuracy nor substantially
    increase in bias when compared to dense models. At the same time, we also find
    that, at higher sparsities, pruned models exhibit higher uncertainty in their
    outputs, as well as increased correlations, which we directly link to increased
    bias. We propose easy-to-use criteria which, based only on the uncompressed model,
    establish whether bias will increase with pruning, and identify the samples most
    susceptible to biased predictions post-compression. Our code can be found at https://github.com/IST-DASLab/pruned-vision-model-bias.
acknowledgement: The authors would like to sincerely thank Sara Hooker for her feedback
  during the development of this work. EI was supported in part by the FWF DK VGSCO,
  grant agreement number W1260-N35. AP and DA acknowledge generous ERC support, via
  Starting Grant 805223 ScaleML.
article_processing_charge: No
arxiv: 1
author:
- first_name: Eugenia B
  full_name: Iofinova, Eugenia B
  id: f9a17499-f6e0-11ea-865d-fdf9a3f77117
  last_name: Iofinova
  orcid: 0000-0002-7778-3221
- first_name: Elena-Alexandra
  full_name: Peste, Elena-Alexandra
  id: 32D78294-F248-11E8-B48F-1D18A9856A87
  last_name: Peste
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Iofinova EB, Peste E-A, Alistarh D-A. Bias in pruned vision models: In-depth
    analysis and countermeasures. In: <i>2023 IEEE/CVF Conference on Computer Vision
    and Pattern Recognition</i>. IEEE; 2023:24364-24373. doi:<a href="https://doi.org/10.1109/cvpr52729.2023.02334">10.1109/cvpr52729.2023.02334</a>'
  apa: 'Iofinova, E. B., Peste, E.-A., &#38; Alistarh, D.-A. (2023). Bias in pruned
    vision models: In-depth analysis and countermeasures. In <i>2023 IEEE/CVF Conference
    on Computer Vision and Pattern Recognition</i> (pp. 24364–24373). Vancouver, BC,
    Canada: IEEE. <a href="https://doi.org/10.1109/cvpr52729.2023.02334">https://doi.org/10.1109/cvpr52729.2023.02334</a>'
  chicago: 'Iofinova, Eugenia B, Elena-Alexandra Peste, and Dan-Adrian Alistarh. “Bias
    in Pruned Vision Models: In-Depth Analysis and Countermeasures.” In <i>2023 IEEE/CVF
    Conference on Computer Vision and Pattern Recognition</i>, 24364–73. IEEE, 2023.
    <a href="https://doi.org/10.1109/cvpr52729.2023.02334">https://doi.org/10.1109/cvpr52729.2023.02334</a>.'
  ieee: 'E. B. Iofinova, E.-A. Peste, and D.-A. Alistarh, “Bias in pruned vision models:
    In-depth analysis and countermeasures,” in <i>2023 IEEE/CVF Conference on Computer
    Vision and Pattern Recognition</i>, Vancouver, BC, Canada, 2023, pp. 24364–24373.'
  ista: 'Iofinova EB, Peste E-A, Alistarh D-A. 2023. Bias in pruned vision models:
    In-depth analysis and countermeasures. 2023 IEEE/CVF Conference on Computer Vision
    and Pattern Recognition. CVPR: Conference on Computer Vision and Pattern Recognition,
    24364–24373.'
  mla: 'Iofinova, Eugenia B., et al. “Bias in Pruned Vision Models: In-Depth Analysis
    and Countermeasures.” <i>2023 IEEE/CVF Conference on Computer Vision and Pattern
    Recognition</i>, IEEE, 2023, pp. 24364–73, doi:<a href="https://doi.org/10.1109/cvpr52729.2023.02334">10.1109/cvpr52729.2023.02334</a>.'
  short: E.B. Iofinova, E.-A. Peste, D.-A. Alistarh, in:, 2023 IEEE/CVF Conference
    on Computer Vision and Pattern Recognition, IEEE, 2023, pp. 24364–24373.
conference:
  end_date: 2023-06-24
  location: Vancouver, BC, Canada
  name: 'CVPR: Conference on Computer Vision and Pattern Recognition'
  start_date: 2023-06-17
date_created: 2024-01-10T08:42:40Z
date_published: 2023-08-22T00:00:00Z
date_updated: 2024-01-10T08:59:26Z
day: '22'
department:
- _id: DaAl
- _id: ChLa
doi: 10.1109/cvpr52729.2023.02334
ec_funded: 1
external_id:
  arxiv:
  - '2304.12622'
  isi:
  - '001062531308068'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2304.12622
month: '08'
oa: 1
oa_version: Preprint
page: 24364-24373
project:
- _id: 9B9290DE-BA93-11EA-9121-9846C619BF3A
  grant_number: ' W1260-N35'
  name: Vienna Graduate School on Computational Optimization
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '805223'
  name: Elastic Coordination for Scalable Machine Learning
publication: 2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition
publication_identifier:
  eisbn:
  - '9798350301298'
  eissn:
  - 2575-7075
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/IST-DASLab/pruned-vision-model-bias
status: public
title: 'Bias in pruned vision models: In-depth analysis and countermeasures'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2023'
...
---
_id: '14772'
abstract:
- lang: eng
  text: "Many coupled evolution equations can be described via 2×2-block operator
    matrices of the form A=[ \r\nA\tB\r\nC\tD\r\n ] in a product space X=X1×X2 with
    possibly unbounded entries. Here, the case of diagonally dominant block operator
    matrices is considered, that is, the case where the full operator A can be seen
    as a relatively bounded perturbation of its diagonal part with D(A)=D(A)×D(D)
    though with possibly large relative bound. For such operators the properties of
    sectoriality, R-sectoriality and the boundedness of the H∞-calculus are studied,
    and for these properties perturbation results for possibly large but structured
    perturbations are derived. Thereby, the time dependent parabolic problem associated
    with A can be analyzed in maximal Lpt\r\n-regularity spaces, and this is applied
    to a wide range of problems such as different theories for liquid crystals, an
    artificial Stokes system, strongly damped wave and plate equations, and a Keller-Segel
    model."
acknowledgement: "We would like to thank Tim Binz, Emiel Lorist and Mark Veraar for
  valuable discussions. We also thank the anonymous referees for their helpful comments
  and suggestions, and for the very accurate reading of the manuscript.\r\nThe first
  author has been supported partially by the Nachwuchsring – Network for the promotion
  of young scientists – at TU Kaiserslautern. Both authors have been supported by
  MathApp – Mathematics Applied to Real-World Problems - part of the Research Initiative
  of the Federal State of Rhineland-Palatinate, Germany."
article_number: '110146'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Antonio
  full_name: Agresti, Antonio
  id: 673cd0cc-9b9a-11eb-b144-88f30e1fbb72
  last_name: Agresti
  orcid: 0000-0002-9573-2962
- first_name: Amru
  full_name: Hussein, Amru
  last_name: Hussein
citation:
  ama: Agresti A, Hussein A. Maximal Lp-regularity and H∞-calculus for block operator
    matrices and applications. <i>Journal of Functional Analysis</i>. 2023;285(11).
    doi:<a href="https://doi.org/10.1016/j.jfa.2023.110146">10.1016/j.jfa.2023.110146</a>
  apa: Agresti, A., &#38; Hussein, A. (2023). Maximal Lp-regularity and H∞-calculus
    for block operator matrices and applications. <i>Journal of Functional Analysis</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.jfa.2023.110146">https://doi.org/10.1016/j.jfa.2023.110146</a>
  chicago: Agresti, Antonio, and Amru Hussein. “Maximal Lp-Regularity and H∞-Calculus
    for Block Operator Matrices and Applications.” <i>Journal of Functional Analysis</i>.
    Elsevier, 2023. <a href="https://doi.org/10.1016/j.jfa.2023.110146">https://doi.org/10.1016/j.jfa.2023.110146</a>.
  ieee: A. Agresti and A. Hussein, “Maximal Lp-regularity and H∞-calculus for block
    operator matrices and applications,” <i>Journal of Functional Analysis</i>, vol.
    285, no. 11. Elsevier, 2023.
  ista: Agresti A, Hussein A. 2023. Maximal Lp-regularity and H∞-calculus for block
    operator matrices and applications. Journal of Functional Analysis. 285(11), 110146.
  mla: Agresti, Antonio, and Amru Hussein. “Maximal Lp-Regularity and H∞-Calculus
    for Block Operator Matrices and Applications.” <i>Journal of Functional Analysis</i>,
    vol. 285, no. 11, 110146, Elsevier, 2023, doi:<a href="https://doi.org/10.1016/j.jfa.2023.110146">10.1016/j.jfa.2023.110146</a>.
  short: A. Agresti, A. Hussein, Journal of Functional Analysis 285 (2023).
date_created: 2024-01-10T09:15:18Z
date_published: 2023-12-01T00:00:00Z
date_updated: 2024-01-10T11:24:56Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1016/j.jfa.2023.110146
external_id:
  arxiv:
  - '2108.01962'
  isi:
  - '001081809000001'
file:
- access_level: open_access
  checksum: eda98ca2aa73da91bd074baed34c2b3c
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-10T11:23:57Z
  date_updated: 2024-01-10T11:23:57Z
  file_id: '14789'
  file_name: 2023_JourFunctionalAnalysis_Agresti.pdf
  file_size: 1120592
  relation: main_file
  success: 1
file_date_updated: 2024-01-10T11:23:57Z
has_accepted_license: '1'
intvolume: '       285'
isi: 1
issue: '11'
keyword:
- Analysis
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: Journal of Functional Analysis
publication_identifier:
  issn:
  - 0022-1236
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Maximal Lp-regularity and H∞-calculus for block operator matrices and applications
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 285
year: '2023'
...
---
_id: '14773'
abstract:
- lang: eng
  text: Through a combination of idealized simulations and real-world data, researchers
    are uncovering how internal feedbacks and large-scale motions influence cloud
    dynamics.
article_number: '28'
article_processing_charge: No
article_type: original
author:
- first_name: Caroline J
  full_name: Muller, Caroline J
  id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
  last_name: Muller
  orcid: 0000-0001-5836-5350
- first_name: Sophie
  full_name: Abramian, Sophie
  last_name: Abramian
citation:
  ama: Muller CJ, Abramian S. The cloud dynamics of convective storm systems. <i>Physics
    Today</i>. 2023;76(5). doi:<a href="https://doi.org/10.1063/pt.3.5234">10.1063/pt.3.5234</a>
  apa: Muller, C. J., &#38; Abramian, S. (2023). The cloud dynamics of convective
    storm systems. <i>Physics Today</i>. AIP Publishing. <a href="https://doi.org/10.1063/pt.3.5234">https://doi.org/10.1063/pt.3.5234</a>
  chicago: Muller, Caroline J, and Sophie Abramian. “The Cloud Dynamics of Convective
    Storm Systems.” <i>Physics Today</i>. AIP Publishing, 2023. <a href="https://doi.org/10.1063/pt.3.5234">https://doi.org/10.1063/pt.3.5234</a>.
  ieee: C. J. Muller and S. Abramian, “The cloud dynamics of convective storm systems,”
    <i>Physics Today</i>, vol. 76, no. 5. AIP Publishing, 2023.
  ista: Muller CJ, Abramian S. 2023. The cloud dynamics of convective storm systems.
    Physics Today. 76(5), 28.
  mla: Muller, Caroline J., and Sophie Abramian. “The Cloud Dynamics of Convective
    Storm Systems.” <i>Physics Today</i>, vol. 76, no. 5, 28, AIP Publishing, 2023,
    doi:<a href="https://doi.org/10.1063/pt.3.5234">10.1063/pt.3.5234</a>.
  short: C.J. Muller, S. Abramian, Physics Today 76 (2023).
date_created: 2024-01-10T09:18:04Z
date_published: 2023-05-01T00:00:00Z
date_updated: 2024-01-10T12:38:02Z
day: '01'
department:
- _id: CaMu
doi: 10.1063/pt.3.5234
external_id:
  isi:
  - '000984516100007'
intvolume: '        76'
isi: 1
issue: '5'
keyword:
- General Physics and Astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.lmd.ens.fr/muller/Pubs/2023-MullerAbramianPhysToday.pdf
month: '05'
oa: 1
oa_version: Published Version
publication: Physics Today
publication_identifier:
  eissn:
  - 1945-0699
  issn:
  - 0031-9228
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
status: public
title: The cloud dynamics of convective storm systems
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 76
year: '2023'
...
---
_id: '14774'
abstract:
- lang: eng
  text: Morphogen gradients impart positional information to cells in a homogenous
    tissue field. Fgf8a, a highly conserved growth factor, has been proposed to act
    as a morphogen during zebrafish gastrulation. However, technical limitations have
    so far prevented direct visualization of the endogenous Fgf8a gradient and confirmation
    of its morphogenic activity. Here, we monitor Fgf8a propagation in the developing
    neural plate using a CRISPR/Cas9-mediated EGFP knock-in at the endogenous fgf8a
    locus. By combining sensitive imaging with single-molecule fluorescence correlation
    spectroscopy, we demonstrate that Fgf8a, which is produced at the embryonic margin,
    propagates by diffusion through the extracellular space and forms a graded distribution
    towards the animal pole. Overlaying the Fgf8a gradient curve with expression profiles
    of its downstream targets determines the precise input-output relationship of
    Fgf8a-mediated patterning. Manipulation of the extracellular Fgf8a levels alters
    the signaling outcome, thus establishing Fgf8a as a bona fide morphogen during
    zebrafish gastrulation. Furthermore, by hindering Fgf8a diffusion, we demonstrate
    that extracellular diffusion of the protein from the source is crucial for it
    to achieve its morphogenic potential.
acknowledgement: "We thank members of the Brand lab, as well as Justina Stark (Ivo
  Sbalzarini group, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden,
  Germany) for project-related discussions; Darren Gilmour (University of Zurich),
  Karuna Sampath (University of Warwick) and Gokul Kesavan (Vowels Lifesciences Private
  Limited, Bangalore) for comments on the manuscript; personnel of the CMCB technology
  platform, TU Dresden for imaging and image analysis-related support; and Maurizio
  Abbate (Technical support, Arivis) for help with image analysis. We are also grateful
  to Stapornwongkul and Briscoe for commenting on a preprint version of our work (Stapornwongkul
  and Briscoe, 2022).\r\nThis work was supported by the Deutsche Forschungsgemeinschaft
  (BR 1746/6-2, BR 1746/11-1 and BR 1746/3 to M.B.), by a Cluster of Excellence ‘Physics
  of Life’ seed grant and by institutional funds from Technische Universitat Dresden
  (to M.B.). Open Access funding provided by Technische Universitat Dresden. Deposited
  in PMC for immediate release."
article_number: dev201559
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Rohit K
  full_name: Harish, Rohit K
  id: 1bae78aa-ee0e-11ec-9b76-bc42990f409d
  last_name: Harish
- first_name: Mansi
  full_name: Gupta, Mansi
  last_name: Gupta
- first_name: Daniela
  full_name: Zöller, Daniela
  last_name: Zöller
- first_name: Hella
  full_name: Hartmann, Hella
  last_name: Hartmann
- first_name: Ali
  full_name: Gheisari, Ali
  last_name: Gheisari
- first_name: Anja
  full_name: Machate, Anja
  last_name: Machate
- first_name: Stefan
  full_name: Hans, Stefan
  last_name: Hans
- first_name: Michael
  full_name: Brand, Michael
  last_name: Brand
citation:
  ama: Harish RK, Gupta M, Zöller D, et al. Real-time monitoring of an endogenous
    Fgf8a gradient attests to its role as a morphogen during zebrafish gastrulation.
    <i>Development</i>. 2023;150(19). doi:<a href="https://doi.org/10.1242/dev.201559">10.1242/dev.201559</a>
  apa: Harish, R. K., Gupta, M., Zöller, D., Hartmann, H., Gheisari, A., Machate,
    A., … Brand, M. (2023). Real-time monitoring of an endogenous Fgf8a gradient attests
    to its role as a morphogen during zebrafish gastrulation. <i>Development</i>.
    The Company of Biologists. <a href="https://doi.org/10.1242/dev.201559">https://doi.org/10.1242/dev.201559</a>
  chicago: Harish, Rohit K, Mansi Gupta, Daniela Zöller, Hella Hartmann, Ali Gheisari,
    Anja Machate, Stefan Hans, and Michael Brand. “Real-Time Monitoring of an Endogenous
    Fgf8a Gradient Attests to Its Role as a Morphogen during Zebrafish Gastrulation.”
    <i>Development</i>. The Company of Biologists, 2023. <a href="https://doi.org/10.1242/dev.201559">https://doi.org/10.1242/dev.201559</a>.
  ieee: R. K. Harish <i>et al.</i>, “Real-time monitoring of an endogenous Fgf8a gradient
    attests to its role as a morphogen during zebrafish gastrulation,” <i>Development</i>,
    vol. 150, no. 19. The Company of Biologists, 2023.
  ista: Harish RK, Gupta M, Zöller D, Hartmann H, Gheisari A, Machate A, Hans S, Brand
    M. 2023. Real-time monitoring of an endogenous Fgf8a gradient attests to its role
    as a morphogen during zebrafish gastrulation. Development. 150(19), dev201559.
  mla: Harish, Rohit K., et al. “Real-Time Monitoring of an Endogenous Fgf8a Gradient
    Attests to Its Role as a Morphogen during Zebrafish Gastrulation.” <i>Development</i>,
    vol. 150, no. 19, dev201559, The Company of Biologists, 2023, doi:<a href="https://doi.org/10.1242/dev.201559">10.1242/dev.201559</a>.
  short: R.K. Harish, M. Gupta, D. Zöller, H. Hartmann, A. Gheisari, A. Machate, S.
    Hans, M. Brand, Development 150 (2023).
date_created: 2024-01-10T09:18:54Z
date_published: 2023-10-01T00:00:00Z
date_updated: 2024-01-10T12:45:25Z
day: '01'
ddc:
- '570'
department:
- _id: AnKi
doi: 10.1242/dev.201559
external_id:
  isi:
  - '001097449100002'
  pmid:
  - '37665167'
file:
- access_level: open_access
  checksum: 2d6f52dc33260a9b2352b8f28374ba5f
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-10T12:41:13Z
  date_updated: 2024-01-10T12:41:13Z
  file_id: '14790'
  file_name: 2023_Development_Harish.pdf
  file_size: 12836306
  relation: main_file
  success: 1
file_date_updated: 2024-01-10T12:41:13Z
has_accepted_license: '1'
intvolume: '       150'
isi: 1
issue: '19'
keyword:
- Developmental Biology
- Molecular Biology
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Development
publication_identifier:
  eissn:
  - 1477-9129
  issn:
  - 0950-1991
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
status: public
title: Real-time monitoring of an endogenous Fgf8a gradient attests to its role as
  a morphogen during zebrafish gastrulation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 150
year: '2023'
...
---
_id: '14775'
abstract:
- lang: eng
  text: We establish a quantitative version of the Tracy–Widom law for the largest
    eigenvalue of high-dimensional sample covariance matrices. To be precise, we show
    that the fluctuations of the largest eigenvalue of a sample covariance matrix
    X∗X converge to its Tracy–Widom limit at a rate nearly N−1/3, where X is an M×N
    random matrix whose entries are independent real or complex random variables,
    assuming that both M and N tend to infinity at a constant rate. This result improves
    the previous estimate N−2/9 obtained by Wang (2019). Our proof relies on a Green
    function comparison method (Adv. Math. 229 (2012) 1435–1515) using iterative cumulant
    expansions, the local laws for the Green function and asymptotic properties of
    the correlation kernel of the white Wishart ensemble.
acknowledgement: K. Schnelli was supported by the Swedish Research Council Grants
  VR-2017-05195, and the Knut and Alice Wallenberg Foundation. Y. Xu was supported
  by the Swedish Research Council Grant VR-2017-05195 and the ERC Advanced Grant “RMTBeyond”
  No. 101020331.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Kevin
  full_name: Schnelli, Kevin
  id: 434AD0AE-F248-11E8-B48F-1D18A9856A87
  last_name: Schnelli
  orcid: 0000-0003-0954-3231
- first_name: Yuanyuan
  full_name: Xu, Yuanyuan
  id: 7902bdb1-a2a4-11eb-a164-c9216f71aea3
  last_name: Xu
  orcid: 0000-0003-1559-1205
citation:
  ama: Schnelli K, Xu Y. Convergence rate to the Tracy–Widom laws for the largest
    eigenvalue of sample covariance matrices. <i>The Annals of Applied Probability</i>.
    2023;33(1):677-725. doi:<a href="https://doi.org/10.1214/22-aap1826">10.1214/22-aap1826</a>
  apa: Schnelli, K., &#38; Xu, Y. (2023). Convergence rate to the Tracy–Widom laws
    for the largest eigenvalue of sample covariance matrices. <i>The Annals of Applied
    Probability</i>. Institute of Mathematical Statistics. <a href="https://doi.org/10.1214/22-aap1826">https://doi.org/10.1214/22-aap1826</a>
  chicago: Schnelli, Kevin, and Yuanyuan Xu. “Convergence Rate to the Tracy–Widom
    Laws for the Largest Eigenvalue of Sample Covariance Matrices.” <i>The Annals
    of Applied Probability</i>. Institute of Mathematical Statistics, 2023. <a href="https://doi.org/10.1214/22-aap1826">https://doi.org/10.1214/22-aap1826</a>.
  ieee: K. Schnelli and Y. Xu, “Convergence rate to the Tracy–Widom laws for the largest
    eigenvalue of sample covariance matrices,” <i>The Annals of Applied Probability</i>,
    vol. 33, no. 1. Institute of Mathematical Statistics, pp. 677–725, 2023.
  ista: Schnelli K, Xu Y. 2023. Convergence rate to the Tracy–Widom laws for the largest
    eigenvalue of sample covariance matrices. The Annals of Applied Probability. 33(1),
    677–725.
  mla: Schnelli, Kevin, and Yuanyuan Xu. “Convergence Rate to the Tracy–Widom Laws
    for the Largest Eigenvalue of Sample Covariance Matrices.” <i>The Annals of Applied
    Probability</i>, vol. 33, no. 1, Institute of Mathematical Statistics, 2023, pp.
    677–725, doi:<a href="https://doi.org/10.1214/22-aap1826">10.1214/22-aap1826</a>.
  short: K. Schnelli, Y. Xu, The Annals of Applied Probability 33 (2023) 677–725.
date_created: 2024-01-10T09:23:31Z
date_published: 2023-02-01T00:00:00Z
date_updated: 2024-01-10T13:31:46Z
day: '01'
department:
- _id: LaEr
doi: 10.1214/22-aap1826
ec_funded: 1
external_id:
  arxiv:
  - '2108.02728'
  isi:
  - '000946432400021'
intvolume: '        33'
isi: 1
issue: '1'
keyword:
- Statistics
- Probability and Uncertainty
- Statistics and Probability
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2108.02728
month: '02'
oa: 1
oa_version: Preprint
page: 677-725
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: The Annals of Applied Probability
publication_identifier:
  issn:
  - 1050-5164
publication_status: published
publisher: Institute of Mathematical Statistics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Convergence rate to the Tracy–Widom laws for the largest eigenvalue of sample
  covariance matrices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2023'
...
---
_id: '14776'
abstract:
- lang: eng
  text: Soluble chaperones residing in the endoplasmic reticulum (ER) play vitally
    important roles in folding and quality control of newly synthesized proteins that
    transiently pass through the ER en route to their final destinations. These soluble
    residents of the ER are themselves endowed with an ER retrieval signal that enables
    the cell to bring the escaped residents back from the Golgi. Here, by using purified
    proteins, we showed that Nicotiana tabacum phytaspase, a plant aspartate-specific
    protease, introduces two breaks at the C-terminus of the N. tabacum ER resident
    calreticulin-3. These cleavages resulted in removal of either a dipeptide or a
    hexapeptide from the C-terminus of calreticulin-3 encompassing part or all of
    the ER retrieval signal. Consistently, expression of the calreticulin-3 derivative
    mimicking the phytaspase cleavage product in Nicotiana benthamiana cells demonstrated
    loss of the ER accumulation of the protein. Notably, upon its escape from the
    ER, calreticulin-3 was further processed by an unknown protease(s) to generate
    the free N-terminal (N) domain of calreticulin-3, which was ultimately secreted
    into the apoplast. Our study thus identified a specific proteolytic enzyme capable
    of precise detachment of the ER retrieval signal from a plant ER resident protein,
    with implications for the further fate of the escaped resident.
acknowledgement: "We thank C.U.T. Hellen for critically reading the manuscript. The
  MALDI MS facility and CLSM became available to us in the framework of Moscow State
  University Development Programs PNG 5.13 and PNR 5.13.\r\nThis work was funded by
  the Russian Science Foundation, grant numbers 19-14-00010 and 22-14-00071."
article_number: '16527'
article_processing_charge: Yes
article_type: original
author:
- first_name: Anastasiia
  full_name: Teplova, Anastasiia
  id: e3736151-106c-11ec-b916-c2558e2762c6
  last_name: Teplova
- first_name: Artemii A.
  full_name: Pigidanov, Artemii A.
  last_name: Pigidanov
- first_name: Marina V.
  full_name: Serebryakova, Marina V.
  last_name: Serebryakova
- first_name: Sergei A.
  full_name: Golyshev, Sergei A.
  last_name: Golyshev
- first_name: Raisa A.
  full_name: Galiullina, Raisa A.
  last_name: Galiullina
- first_name: Nina V.
  full_name: Chichkova, Nina V.
  last_name: Chichkova
- first_name: Andrey B.
  full_name: Vartapetian, Andrey B.
  last_name: Vartapetian
citation:
  ama: Teplova A, Pigidanov AA, Serebryakova MV, et al. Phytaspase Is capable of detaching
    the endoplasmic reticulum retrieval signal from tobacco calreticulin-3. <i>International
    Journal of Molecular Sciences</i>. 2023;24(22). doi:<a href="https://doi.org/10.3390/ijms242216527">10.3390/ijms242216527</a>
  apa: Teplova, A., Pigidanov, A. A., Serebryakova, M. V., Golyshev, S. A., Galiullina,
    R. A., Chichkova, N. V., &#38; Vartapetian, A. B. (2023). Phytaspase Is capable
    of detaching the endoplasmic reticulum retrieval signal from tobacco calreticulin-3.
    <i>International Journal of Molecular Sciences</i>. MDPI. <a href="https://doi.org/10.3390/ijms242216527">https://doi.org/10.3390/ijms242216527</a>
  chicago: Teplova, Anastasiia, Artemii A. Pigidanov, Marina V. Serebryakova, Sergei
    A. Golyshev, Raisa A. Galiullina, Nina V. Chichkova, and Andrey B. Vartapetian.
    “Phytaspase Is Capable of Detaching the Endoplasmic Reticulum Retrieval Signal
    from Tobacco Calreticulin-3.” <i>International Journal of Molecular Sciences</i>.
    MDPI, 2023. <a href="https://doi.org/10.3390/ijms242216527">https://doi.org/10.3390/ijms242216527</a>.
  ieee: A. Teplova <i>et al.</i>, “Phytaspase Is capable of detaching the endoplasmic
    reticulum retrieval signal from tobacco calreticulin-3,” <i>International Journal
    of Molecular Sciences</i>, vol. 24, no. 22. MDPI, 2023.
  ista: Teplova A, Pigidanov AA, Serebryakova MV, Golyshev SA, Galiullina RA, Chichkova
    NV, Vartapetian AB. 2023. Phytaspase Is capable of detaching the endoplasmic reticulum
    retrieval signal from tobacco calreticulin-3. International Journal of Molecular
    Sciences. 24(22), 16527.
  mla: Teplova, Anastasiia, et al. “Phytaspase Is Capable of Detaching the Endoplasmic
    Reticulum Retrieval Signal from Tobacco Calreticulin-3.” <i>International Journal
    of Molecular Sciences</i>, vol. 24, no. 22, 16527, MDPI, 2023, doi:<a href="https://doi.org/10.3390/ijms242216527">10.3390/ijms242216527</a>.
  short: A. Teplova, A.A. Pigidanov, M.V. Serebryakova, S.A. Golyshev, R.A. Galiullina,
    N.V. Chichkova, A.B. Vartapetian, International Journal of Molecular Sciences
    24 (2023).
date_created: 2024-01-10T09:24:35Z
date_published: 2023-11-01T00:00:00Z
date_updated: 2024-01-10T13:41:10Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.3390/ijms242216527
external_id:
  isi:
  - '001113792600001'
  pmid:
  - '38003717'
file:
- access_level: open_access
  checksum: 4df7d206ba022b7f54eff1f0aec1659a
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-10T13:39:42Z
  date_updated: 2024-01-10T13:39:42Z
  file_id: '14791'
  file_name: 2023_IJMS_Teplova.pdf
  file_size: 2637784
  relation: main_file
  success: 1
file_date_updated: 2024-01-10T13:39:42Z
has_accepted_license: '1'
intvolume: '        24'
isi: 1
issue: '22'
keyword:
- Inorganic Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Computer Science Applications
- Spectroscopy
- Molecular Biology
- General Medicine
- Catalysis
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: International Journal of Molecular Sciences
publication_identifier:
  issn:
  - 1422-0067
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Phytaspase Is capable of detaching the endoplasmic reticulum retrieval signal
  from tobacco calreticulin-3
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2023'
...
---
_id: '14777'
abstract:
- lang: eng
  text: The effects of the partial V-substitution for Ag on the thermoelectric (TE)
    properties are investigated for a flexible semiconducting compound Ag2S0.55Se0.45.
    Density functional theory calculations predict that such a partial V-substitution
    constructively modifies the electronic structure near the bottom of the conduction
    band to improve the TE performance. The synthesized Ag1.97V0.03S0.55Se0.45 is
    found to possess a TE dimensionless figure-of-merit (ZT) of 0.71 at 350 K with
    maintaining its flexible nature. This ZT value is relatively high in comparison
    with those reported for flexible TE materials below 360 K. The increase in the
    ZT value is caused by the enhanced absolute value of the Seebeck coefficient with
    less significant variation in electrical resistivity. The high ZT value with the
    flexible nature naturally allows us to employ the Ag1.97V0.03S0.55Se0.45 as a
    component of flexible TE generators.
acknowledgement: This work received financial support partially from Japan Science
  and Technology Agency (JST) CREST Grant No. JPMJCR18I2, Japan. The powder-XRD experiments
  were conducted at BL5S2 of Aichi Synchrotron Radiation Center, Aichi Science & Technology
  Foundation, Aichi, Japan (Proposal No. 202301057).
article_number: '125206'
article_processing_charge: Yes
article_type: original
author:
- first_name: Kosuke
  full_name: Sato, Kosuke
  last_name: Sato
- first_name: Saurabh
  full_name: Singh, Saurabh
  id: 12d625da-9cb3-11ed-9667-af09d37d3f0a
  last_name: Singh
  orcid: 0000-0003-2209-5269
- first_name: Itsuki
  full_name: Yamazaki, Itsuki
  last_name: Yamazaki
- first_name: Keisuke
  full_name: Hirata, Keisuke
  last_name: Hirata
- first_name: Artoni Kevin R.
  full_name: Ang, Artoni Kevin R.
  last_name: Ang
- first_name: Masaharu
  full_name: Matsunami, Masaharu
  last_name: Matsunami
- first_name: Tsunehiro
  full_name: Takeuchi, Tsunehiro
  last_name: Takeuchi
citation:
  ama: Sato K, Singh S, Yamazaki I, et al. Improvement of thermoelectric performance
    of flexible compound Ag2S0.55Se0.45 by means of partial V-substitution for Ag.
    <i>AIP Advances</i>. 2023;13(12). doi:<a href="https://doi.org/10.1063/5.0171888">10.1063/5.0171888</a>
  apa: Sato, K., Singh, S., Yamazaki, I., Hirata, K., Ang, A. K. R., Matsunami, M.,
    &#38; Takeuchi, T. (2023). Improvement of thermoelectric performance of flexible
    compound Ag2S0.55Se0.45 by means of partial V-substitution for Ag. <i>AIP Advances</i>.
    AIP Publishing. <a href="https://doi.org/10.1063/5.0171888">https://doi.org/10.1063/5.0171888</a>
  chicago: Sato, Kosuke, Saurabh Singh, Itsuki Yamazaki, Keisuke Hirata, Artoni Kevin
    R. Ang, Masaharu Matsunami, and Tsunehiro Takeuchi. “Improvement of Thermoelectric
    Performance of Flexible Compound Ag2S0.55Se0.45 by Means of Partial V-Substitution
    for Ag.” <i>AIP Advances</i>. AIP Publishing, 2023. <a href="https://doi.org/10.1063/5.0171888">https://doi.org/10.1063/5.0171888</a>.
  ieee: K. Sato <i>et al.</i>, “Improvement of thermoelectric performance of flexible
    compound Ag2S0.55Se0.45 by means of partial V-substitution for Ag,” <i>AIP Advances</i>,
    vol. 13, no. 12. AIP Publishing, 2023.
  ista: Sato K, Singh S, Yamazaki I, Hirata K, Ang AKR, Matsunami M, Takeuchi T. 2023.
    Improvement of thermoelectric performance of flexible compound Ag2S0.55Se0.45
    by means of partial V-substitution for Ag. AIP Advances. 13(12), 125206.
  mla: Sato, Kosuke, et al. “Improvement of Thermoelectric Performance of Flexible
    Compound Ag2S0.55Se0.45 by Means of Partial V-Substitution for Ag.” <i>AIP Advances</i>,
    vol. 13, no. 12, 125206, AIP Publishing, 2023, doi:<a href="https://doi.org/10.1063/5.0171888">10.1063/5.0171888</a>.
  short: K. Sato, S. Singh, I. Yamazaki, K. Hirata, A.K.R. Ang, M. Matsunami, T. Takeuchi,
    AIP Advances 13 (2023).
date_created: 2024-01-10T09:26:08Z
date_published: 2023-12-01T00:00:00Z
date_updated: 2024-01-10T13:49:09Z
day: '01'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1063/5.0171888
external_id:
  isi:
  - '001114917200005'
file:
- access_level: open_access
  checksum: a7098388b8ff822b47f5ddd37ed3bdbc
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-10T13:47:31Z
  date_updated: 2024-01-10T13:47:31Z
  file_id: '14792'
  file_name: 2023_AIPAdvances_Sato.pdf
  file_size: 9676071
  relation: main_file
  success: 1
file_date_updated: 2024-01-10T13:47:31Z
has_accepted_license: '1'
intvolume: '        13'
isi: 1
issue: '12'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: AIP Advances
publication_identifier:
  eissn:
  - 2158-3226
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
status: public
title: Improvement of thermoelectric performance of flexible compound Ag2S0.55Se0.45
  by means of partial V-substitution for Ag
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2023'
...
---
_id: '14778'
abstract:
- lang: eng
  text: 'We consider the almost-sure (a.s.) termination problem for probabilistic
    programs, which are a stochastic extension of classical imperative programs. Lexicographic
    ranking functions provide a sound and practical approach for termination of non-probabilistic
    programs, and their extension to probabilistic programs is achieved via lexicographic
    ranking supermartingales (LexRSMs). However, LexRSMs introduced in the previous
    work have a limitation that impedes their automation: all of their components
    have to be non-negative in all reachable states. This might result in a LexRSM
    not existing even for simple terminating programs. Our contributions are twofold.
    First, we introduce a generalization of LexRSMs that allows for some components
    to be negative. This standard feature of non-probabilistic termination proofs
    was hitherto not known to be sound in the probabilistic setting, as the soundness
    proof requires a careful analysis of the underlying stochastic process. Second,
    we present polynomial-time algorithms using our generalized LexRSMs for proving
    a.s. termination in broad classes of linear-arithmetic programs.'
acknowledgement: This research was partially supported by the ERC CoG (grant no. 863818;
  ForM-SMArt), the Czech Science Foundation (grant no. GA21-24711S), and the European
  Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie
  Grant Agreement No. 665385.
article_number: '11'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Ehsan
  full_name: Kafshdar Goharshady, Ehsan
  last_name: Kafshdar Goharshady
- first_name: Petr
  full_name: Novotný, Petr
  id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
  last_name: Novotný
- first_name: Jiří
  full_name: Zárevúcky, Jiří
  last_name: Zárevúcky
- first_name: Dorde
  full_name: Zikelic, Dorde
  id: 294AA7A6-F248-11E8-B48F-1D18A9856A87
  last_name: Zikelic
  orcid: 0000-0002-4681-1699
citation:
  ama: Chatterjee K, Kafshdar Goharshady E, Novotný P, Zárevúcky J, Zikelic D. On
    lexicographic proof rules for probabilistic termination. <i>Formal Aspects of
    Computing</i>. 2023;35(2). doi:<a href="https://doi.org/10.1145/3585391">10.1145/3585391</a>
  apa: Chatterjee, K., Kafshdar Goharshady, E., Novotný, P., Zárevúcky, J., &#38;
    Zikelic, D. (2023). On lexicographic proof rules for probabilistic termination.
    <i>Formal Aspects of Computing</i>. Association for Computing Machinery. <a href="https://doi.org/10.1145/3585391">https://doi.org/10.1145/3585391</a>
  chicago: Chatterjee, Krishnendu, Ehsan Kafshdar Goharshady, Petr Novotný, Jiří Zárevúcky,
    and Dorde Zikelic. “On Lexicographic Proof Rules for Probabilistic Termination.”
    <i>Formal Aspects of Computing</i>. Association for Computing Machinery, 2023.
    <a href="https://doi.org/10.1145/3585391">https://doi.org/10.1145/3585391</a>.
  ieee: K. Chatterjee, E. Kafshdar Goharshady, P. Novotný, J. Zárevúcky, and D. Zikelic,
    “On lexicographic proof rules for probabilistic termination,” <i>Formal Aspects
    of Computing</i>, vol. 35, no. 2. Association for Computing Machinery, 2023.
  ista: Chatterjee K, Kafshdar Goharshady E, Novotný P, Zárevúcky J, Zikelic D. 2023.
    On lexicographic proof rules for probabilistic termination. Formal Aspects of
    Computing. 35(2), 11.
  mla: Chatterjee, Krishnendu, et al. “On Lexicographic Proof Rules for Probabilistic
    Termination.” <i>Formal Aspects of Computing</i>, vol. 35, no. 2, 11, Association
    for Computing Machinery, 2023, doi:<a href="https://doi.org/10.1145/3585391">10.1145/3585391</a>.
  short: K. Chatterjee, E. Kafshdar Goharshady, P. Novotný, J. Zárevúcky, D. Zikelic,
    Formal Aspects of Computing 35 (2023).
date_created: 2024-01-10T09:27:43Z
date_published: 2023-06-23T00:00:00Z
date_updated: 2025-07-14T09:10:10Z
day: '23'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1145/3585391
ec_funded: 1
external_id:
  arxiv:
  - '2108.02188'
file:
- access_level: open_access
  checksum: 3bb133eeb27ec01649a9a36445d952d9
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  creator: dernst
  date_created: 2024-01-16T08:11:24Z
  date_updated: 2024-01-16T08:11:24Z
  file_id: '14804'
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  file_size: 502522
  relation: main_file
  success: 1
file_date_updated: 2024-01-16T08:11:24Z
has_accepted_license: '1'
intvolume: '        35'
issue: '2'
keyword:
- Theoretical Computer Science
- Software
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: Formal Aspects of Computing
publication_identifier:
  eissn:
  - 1433-299X
  issn:
  - 0934-5043
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
related_material:
  record:
  - id: '10414'
    relation: earlier_version
    status: public
status: public
title: On lexicographic proof rules for probabilistic termination
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2023'
...
---
_id: '14779'
abstract:
- lang: eng
  text: The presence of a developed boundary layer decouples a glacier's response
    from ambient conditions, suggesting that sensitivity to climate change is increased
    by glacier retreat. To test this hypothesis, we explore six years of distributed
    meteorological data on a small Swiss glacier in the period 2001–2022. Large glacier
    fragmentation has occurred since 2001 (−35% area change up to 2022) coinciding
    with notable frontal retreat, an observed switch from down‐glacier katabatic to
    up‐glacier valley winds and an increased sensitivity (ratio) of on‐glacier to
    off‐glacier temperature. As the glacier ceases to develop density‐driven katabatic
    winds, sensible heat fluxes on the glacier are increasingly determined by the
    conditions occurring outside the boundary layer of the glacier, sealing the glacier's
    demise as the climate continues to warm and experience an increased frequency
    of extreme summers.
acknowledgement: This work was funded by the EU Horizon 2020 Marie Skłodowska-Curie
  Actions Grant 101026058. The authors acknowl-edge the dedicated collection of field
  data by many parties since 2001, including those acknowledged for the cited works
  on Arolla Glacier. The authors would like to thank Fabienne Meier, Alice Zaugg,
  Raphael Willi, Maria Grundmann, and Marta Corrà for assistance in the field for
  the summers of 2021 and 2022. Off-glacier data provided by Grand Dixence SA (Arolla)
  and MeteoSwiss are kindly acknowledged. Simone Fatichi is thanked for the provision
  and support in the use of the Tethys-Chloris model. We thank Editor Mathieu Morlighem
  and two anonymous reviewers whose comments have helped to improve the quality of
  the manuscript.
article_number: e2023GL103043
article_processing_charge: No
article_type: original
author:
- first_name: Thomas E.
  full_name: Shaw, Thomas E.
  last_name: Shaw
- first_name: Pascal
  full_name: Buri, Pascal
  last_name: Buri
- first_name: Michael
  full_name: McCarthy, Michael
  last_name: McCarthy
- first_name: Evan S.
  full_name: Miles, Evan S.
  last_name: Miles
- first_name: Álvaro
  full_name: Ayala, Álvaro
  last_name: Ayala
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
  orcid: 0000-0002-5554-8087
citation:
  ama: Shaw TE, Buri P, McCarthy M, Miles ES, Ayala Á, Pellicciotti F. The decaying
    near‐surface boundary layer of a retreating alpine glacier. <i>Geophysical Research
    Letters</i>. 2023;50(11). doi:<a href="https://doi.org/10.1029/2023gl103043">10.1029/2023gl103043</a>
  apa: Shaw, T. E., Buri, P., McCarthy, M., Miles, E. S., Ayala, Á., &#38; Pellicciotti,
    F. (2023). The decaying near‐surface boundary layer of a retreating alpine glacier.
    <i>Geophysical Research Letters</i>. American Geophysical Union. <a href="https://doi.org/10.1029/2023gl103043">https://doi.org/10.1029/2023gl103043</a>
  chicago: Shaw, Thomas E., Pascal Buri, Michael McCarthy, Evan S. Miles, Álvaro Ayala,
    and Francesca Pellicciotti. “The Decaying Near‐surface Boundary Layer of a Retreating
    Alpine Glacier.” <i>Geophysical Research Letters</i>. American Geophysical Union,
    2023. <a href="https://doi.org/10.1029/2023gl103043">https://doi.org/10.1029/2023gl103043</a>.
  ieee: T. E. Shaw, P. Buri, M. McCarthy, E. S. Miles, Á. Ayala, and F. Pellicciotti,
    “The decaying near‐surface boundary layer of a retreating alpine glacier,” <i>Geophysical
    Research Letters</i>, vol. 50, no. 11. American Geophysical Union, 2023.
  ista: Shaw TE, Buri P, McCarthy M, Miles ES, Ayala Á, Pellicciotti F. 2023. The
    decaying near‐surface boundary layer of a retreating alpine glacier. Geophysical
    Research Letters. 50(11), e2023GL103043.
  mla: Shaw, Thomas E., et al. “The Decaying Near‐surface Boundary Layer of a Retreating
    Alpine Glacier.” <i>Geophysical Research Letters</i>, vol. 50, no. 11, e2023GL103043,
    American Geophysical Union, 2023, doi:<a href="https://doi.org/10.1029/2023gl103043">10.1029/2023gl103043</a>.
  short: T.E. Shaw, P. Buri, M. McCarthy, E.S. Miles, Á. Ayala, F. Pellicciotti, Geophysical
    Research Letters 50 (2023).
date_created: 2024-01-10T09:28:34Z
date_published: 2023-06-16T00:00:00Z
date_updated: 2024-01-16T08:42:36Z
day: '16'
ddc:
- '550'
department:
- _id: FrPe
doi: 10.1029/2023gl103043
external_id:
  isi:
  - '000999436400001'
file:
- access_level: open_access
  checksum: 391a3005c95340a0ae129ce4fbdf2bae
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-16T08:35:02Z
  date_updated: 2024-01-16T08:35:02Z
  file_id: '14805'
  file_name: 2023_GeophysicalResearchLetter_Shaw.pdf
  file_size: 2529327
  relation: main_file
  success: 1
file_date_updated: 2024-01-16T08:35:02Z
has_accepted_license: '1'
intvolume: '        50'
isi: 1
issue: '11'
keyword:
- General Earth and Planetary Sciences
- Geophysics
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Geophysical Research Letters
publication_identifier:
  eissn:
  - 1944-8007
  issn:
  - 0094-8276
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
status: public
title: The decaying near‐surface boundary layer of a retreating alpine glacier
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 50
year: '2023'
...
---
_id: '14780'
abstract:
- lang: eng
  text: In this paper, we study the eigenvalues and eigenvectors of the spiked invariant
    multiplicative models when the randomness is from Haar matrices. We establish
    the limits of the outlier eigenvalues λˆi and the generalized components (⟨v,uˆi⟩
    for any deterministic vector v) of the outlier eigenvectors uˆi with optimal convergence
    rates. Moreover, we prove that the non-outlier eigenvalues stick with those of
    the unspiked matrices and the non-outlier eigenvectors are delocalized. The results
    also hold near the so-called BBP transition and for degenerate spikes. On one
    hand, our results can be regarded as a refinement of the counterparts of [12]
    under additional regularity conditions. On the other hand, they can be viewed
    as an analog of [34] by replacing the random matrix with i.i.d. entries with Haar
    random matrix.
acknowledgement: The authors would like to thank the editor, the associated editor
  and two anonymous referees for their many critical suggestions which have significantly
  improved the paper. The authors are also grateful to Zhigang Bao and Ji Oon Lee
  for many helpful discussions. The first author also wants to thank Hari Bercovici
  for many useful comments. The first author is partially supported by National Science
  Foundation DMS-2113489 and the second author is supported by ERC Advanced Grant
  “RMTBeyond” No. 101020331.
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Xiucai
  full_name: Ding, Xiucai
  last_name: Ding
- first_name: Hong Chang
  full_name: Ji, Hong Chang
  id: dd216c0a-c1f9-11eb-beaf-e9ea9d2de76d
  last_name: Ji
citation:
  ama: Ding X, Ji HC. Spiked multiplicative random matrices and principal components.
    <i>Stochastic Processes and their Applications</i>. 2023;163:25-60. doi:<a href="https://doi.org/10.1016/j.spa.2023.05.009">10.1016/j.spa.2023.05.009</a>
  apa: Ding, X., &#38; Ji, H. C. (2023). Spiked multiplicative random matrices and
    principal components. <i>Stochastic Processes and Their Applications</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.spa.2023.05.009">https://doi.org/10.1016/j.spa.2023.05.009</a>
  chicago: Ding, Xiucai, and Hong Chang Ji. “Spiked Multiplicative Random Matrices
    and Principal Components.” <i>Stochastic Processes and Their Applications</i>.
    Elsevier, 2023. <a href="https://doi.org/10.1016/j.spa.2023.05.009">https://doi.org/10.1016/j.spa.2023.05.009</a>.
  ieee: X. Ding and H. C. Ji, “Spiked multiplicative random matrices and principal
    components,” <i>Stochastic Processes and their Applications</i>, vol. 163. Elsevier,
    pp. 25–60, 2023.
  ista: Ding X, Ji HC. 2023. Spiked multiplicative random matrices and principal components.
    Stochastic Processes and their Applications. 163, 25–60.
  mla: Ding, Xiucai, and Hong Chang Ji. “Spiked Multiplicative Random Matrices and
    Principal Components.” <i>Stochastic Processes and Their Applications</i>, vol.
    163, Elsevier, 2023, pp. 25–60, doi:<a href="https://doi.org/10.1016/j.spa.2023.05.009">10.1016/j.spa.2023.05.009</a>.
  short: X. Ding, H.C. Ji, Stochastic Processes and Their Applications 163 (2023)
    25–60.
date_created: 2024-01-10T09:29:25Z
date_published: 2023-09-01T00:00:00Z
date_updated: 2024-01-16T08:49:51Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1016/j.spa.2023.05.009
ec_funded: 1
external_id:
  arxiv:
  - '2302.13502'
  isi:
  - '001113615900001'
file:
- access_level: open_access
  checksum: 46a708b0cd5569a73d0f3d6c3e0a44dc
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-16T08:47:31Z
  date_updated: 2024-01-16T08:47:31Z
  file_id: '14806'
  file_name: 2023_StochasticProcAppl_Ding.pdf
  file_size: 1870349
  relation: main_file
  success: 1
file_date_updated: 2024-01-16T08:47:31Z
has_accepted_license: '1'
intvolume: '       163'
isi: 1
keyword:
- Applied Mathematics
- Modeling and Simulation
- Statistics and Probability
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 25-60
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Stochastic Processes and their Applications
publication_identifier:
  eissn:
  - 1879-209X
  issn:
  - 0304-4149
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Spiked multiplicative random matrices and principal components
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 163
year: '2023'
...
---
_id: '14781'
abstract:
- lang: eng
  text: Germ granules, condensates of phase-separated RNA and protein, are organelles
    that are essential for germline development in different organisms. The patterning
    of the granules and their relevance for germ cell fate are not fully understood.
    Combining three-dimensional in vivo structural and functional analyses, we study
    the dynamic spatial organization of molecules within zebrafish germ granules.
    We find that the localization of RNA molecules to the periphery of the granules,
    where ribosomes are localized, depends on translational activity at this location.
    In addition, we find that the vertebrate-specific Dead end (Dnd1) protein is essential
    for nanos3 RNA localization at the condensates’ periphery. Accordingly, in the
    absence of Dnd1, or when translation is inhibited, nanos3 RNA translocates into
    the granule interior, away from the ribosomes, a process that is correlated with
    the loss of germ cell fate. These findings highlight the relevance of sub-granule
    compartmentalization for post-transcriptional control and its importance for preserving
    germ cell totipotency.
acknowledgement: We thank Celeste Brennecka for editing and Michal Reichman-Fried
  for critical comments on the manuscript. We thank Ursula Jordan, Esther Messerschmidt,
  and Ines Sandbote for technical assistance. This work was supported by funding from
  the University of Münster (K.J.W., K.T., E.R., A.G., T.G.-T., J.S., and M.G.), the
  Max Planck Institute for Molecular Biomedicine (D.Z.), the German Research Foundation
  grant CRU 326 (P2) RA863/12-2 (E.R.), Baylor University (K.H. and D.R.), and the
  National Institutes of Health grant R35 GM 134910 (D.R.). We thank the referees
  for insightful comments that helped improve the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Kim Joana
  full_name: Westerich, Kim Joana
  last_name: Westerich
- first_name: Katsiaryna
  full_name: Tarbashevich, Katsiaryna
  last_name: Tarbashevich
- first_name: Jan
  full_name: Schick, Jan
  last_name: Schick
- first_name: Antra
  full_name: Gupta, Antra
  last_name: Gupta
- first_name: Mingzhao
  full_name: Zhu, Mingzhao
  last_name: Zhu
- first_name: Kenneth
  full_name: Hull, Kenneth
  last_name: Hull
- first_name: Daniel
  full_name: Romo, Daniel
  last_name: Romo
- first_name: Dagmar
  full_name: Zeuschner, Dagmar
  last_name: Zeuschner
- first_name: Mohammad
  full_name: Goudarzi, Mohammad
  id: 3384113A-F248-11E8-B48F-1D18A9856A87
  last_name: Goudarzi
- first_name: Theresa
  full_name: Gross-Thebing, Theresa
  last_name: Gross-Thebing
- first_name: Erez
  full_name: Raz, Erez
  last_name: Raz
citation:
  ama: Westerich KJ, Tarbashevich K, Schick J, et al. Spatial organization and function
    of RNA molecules within phase-separated condensates in zebrafish are controlled
    by Dnd1. <i>Developmental Cell</i>. 2023;58(17):1578-1592.e5. doi:<a href="https://doi.org/10.1016/j.devcel.2023.06.009">10.1016/j.devcel.2023.06.009</a>
  apa: Westerich, K. J., Tarbashevich, K., Schick, J., Gupta, A., Zhu, M., Hull, K.,
    … Raz, E. (2023). Spatial organization and function of RNA molecules within phase-separated
    condensates in zebrafish are controlled by Dnd1. <i>Developmental Cell</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.devcel.2023.06.009">https://doi.org/10.1016/j.devcel.2023.06.009</a>
  chicago: Westerich, Kim Joana, Katsiaryna Tarbashevich, Jan Schick, Antra Gupta,
    Mingzhao Zhu, Kenneth Hull, Daniel Romo, et al. “Spatial Organization and Function
    of RNA Molecules within Phase-Separated Condensates in Zebrafish Are Controlled
    by Dnd1.” <i>Developmental Cell</i>. Elsevier, 2023. <a href="https://doi.org/10.1016/j.devcel.2023.06.009">https://doi.org/10.1016/j.devcel.2023.06.009</a>.
  ieee: K. J. Westerich <i>et al.</i>, “Spatial organization and function of RNA molecules
    within phase-separated condensates in zebrafish are controlled by Dnd1,” <i>Developmental
    Cell</i>, vol. 58, no. 17. Elsevier, p. 1578–1592.e5, 2023.
  ista: Westerich KJ, Tarbashevich K, Schick J, Gupta A, Zhu M, Hull K, Romo D, Zeuschner
    D, Goudarzi M, Gross-Thebing T, Raz E. 2023. Spatial organization and function
    of RNA molecules within phase-separated condensates in zebrafish are controlled
    by Dnd1. Developmental Cell. 58(17), 1578–1592.e5.
  mla: Westerich, Kim Joana, et al. “Spatial Organization and Function of RNA Molecules
    within Phase-Separated Condensates in Zebrafish Are Controlled by Dnd1.” <i>Developmental
    Cell</i>, vol. 58, no. 17, Elsevier, 2023, p. 1578–1592.e5, doi:<a href="https://doi.org/10.1016/j.devcel.2023.06.009">10.1016/j.devcel.2023.06.009</a>.
  short: K.J. Westerich, K. Tarbashevich, J. Schick, A. Gupta, M. Zhu, K. Hull, D.
    Romo, D. Zeuschner, M. Goudarzi, T. Gross-Thebing, E. Raz, Developmental Cell
    58 (2023) 1578–1592.e5.
date_created: 2024-01-10T09:41:21Z
date_published: 2023-09-11T00:00:00Z
date_updated: 2024-01-16T08:56:36Z
day: '11'
department:
- _id: Bio
doi: 10.1016/j.devcel.2023.06.009
external_id:
  pmid:
  - '37463577'
intvolume: '        58'
issue: '17'
keyword:
- Developmental Biology
- Cell Biology
- General Biochemistry
- Genetics and Molecular Biology
- Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.biorxiv.org/content/10.1101/2023.07.09.548244
month: '09'
oa: 1
oa_version: Preprint
page: 1578-1592.e5
pmid: 1
publication: Developmental Cell
publication_identifier:
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Spatial organization and function of RNA molecules within phase-separated condensates
  in zebrafish are controlled by Dnd1
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2023'
...
---
_id: '14782'
abstract:
- lang: eng
  text: The actin cortex is a complex cytoskeletal machinery that drives and responds
    to changes in cell shape. It must generate or adapt to plasma membrane curvature
    to facilitate diverse functions such as cell division, migration, and phagocytosis.
    Due to the complex molecular makeup of the actin cortex, it remains unclear whether
    actin networks are inherently able to sense and generate membrane curvature, or
    whether they rely on their diverse binding partners to accomplish this. Here,
    we show that curvature sensing is an inherent capability of branched actin networks
    nucleated by Arp2/3 and VCA. We develop a robust method to encapsulate actin inside
    giant unilamellar vesicles (GUVs) and assemble an actin cortex at the inner surface
    of the GUV membrane. We show that actin forms a uniform and thin cortical layer
    when present at high concentration and distinct patches associated with negative
    membrane curvature at low concentration. Serendipitously, we find that the GUV
    production method also produces dumbbell-shaped GUVs, which we explain using mathematical
    modeling in terms of membrane hemifusion of nested GUVs. We find that branched
    actin networks preferentially assemble at the neck of the dumbbells, which possess
    a micrometer-range convex curvature comparable with the curvature of the actin
    patches found in spherical GUVs. Minimal branched actin networks can thus sense
    membrane curvature, which may help mammalian cells to robustly recruit actin to
    curved membranes to facilitate diverse cellular functions such as cytokinesis
    and migration.
acknowledgement: We thank Jeffrey den Haan for protein purification, Kristina Ganzinger
  (AMOLF) for providing the 10xHis VCA construct, David Kovar (University of Chicago)
  for the CP constructs, and Michael Way (Crick Institute) for providing purified
  human Arp2/3 proteins. We are grateful to Iris Lambert for early actin encapsulation
  experiments that formed the basis for establishing the eDICE method, to Federico
  Fanalista for acquiring images of dumbbell-shaped GUVs in samples produced by cDICE,
  and to Tom Aarts for images of dumbbell-shaped GUVs produced by gel-assisted swelling.
  Lennard van Buren is thanked for his help with image analysis to quantify actin
  concentrations in GUVs. We thank Kristina Ganzinger (AMOLF) for hosting us to perform
  pyrene assays in her lab, and Balász Antalicz (AMOLF) for technical assistance with
  the spectrophotometer. The authors also thank Matthieu Piel and Daniel Fletcher
  for insightful and inspiring discussions. We acknowledge financial support from
  The Netherlands Organization of Scientific Research (NWO/OCW) Gravitation program
  Building a Synthetic Cell (BaSyC) (024.003.019). F.F. gratefully acknowledges funding
  from the Kavli Synergy program of the Kavli Institute of Nanoscience Delft.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Lucia
  full_name: Baldauf, Lucia
  last_name: Baldauf
- first_name: Felix F
  full_name: Frey, Felix F
  id: a0270b37-8f1a-11ec-95c7-8e710c59a4f3
  last_name: Frey
- first_name: Marcos
  full_name: Arribas Perez, Marcos
  last_name: Arribas Perez
- first_name: Timon
  full_name: Idema, Timon
  last_name: Idema
- first_name: Gijsje H.
  full_name: Koenderink, Gijsje H.
  last_name: Koenderink
citation:
  ama: Baldauf L, Frey FF, Arribas Perez M, Idema T, Koenderink GH. Branched actin
    cortices reconstituted in vesicles sense membrane curvature. <i>Biophysical Journal</i>.
    2023;122(11):2311-2324. doi:<a href="https://doi.org/10.1016/j.bpj.2023.02.018">10.1016/j.bpj.2023.02.018</a>
  apa: Baldauf, L., Frey, F. F., Arribas Perez, M., Idema, T., &#38; Koenderink, G.
    H. (2023). Branched actin cortices reconstituted in vesicles sense membrane curvature.
    <i>Biophysical Journal</i>. Elsevier. <a href="https://doi.org/10.1016/j.bpj.2023.02.018">https://doi.org/10.1016/j.bpj.2023.02.018</a>
  chicago: Baldauf, Lucia, Felix F Frey, Marcos Arribas Perez, Timon Idema, and Gijsje
    H. Koenderink. “Branched Actin Cortices Reconstituted in Vesicles Sense Membrane
    Curvature.” <i>Biophysical Journal</i>. Elsevier, 2023. <a href="https://doi.org/10.1016/j.bpj.2023.02.018">https://doi.org/10.1016/j.bpj.2023.02.018</a>.
  ieee: L. Baldauf, F. F. Frey, M. Arribas Perez, T. Idema, and G. H. Koenderink,
    “Branched actin cortices reconstituted in vesicles sense membrane curvature,”
    <i>Biophysical Journal</i>, vol. 122, no. 11. Elsevier, pp. 2311–2324, 2023.
  ista: Baldauf L, Frey FF, Arribas Perez M, Idema T, Koenderink GH. 2023. Branched
    actin cortices reconstituted in vesicles sense membrane curvature. Biophysical
    Journal. 122(11), 2311–2324.
  mla: Baldauf, Lucia, et al. “Branched Actin Cortices Reconstituted in Vesicles Sense
    Membrane Curvature.” <i>Biophysical Journal</i>, vol. 122, no. 11, Elsevier, 2023,
    pp. 2311–24, doi:<a href="https://doi.org/10.1016/j.bpj.2023.02.018">10.1016/j.bpj.2023.02.018</a>.
  short: L. Baldauf, F.F. Frey, M. Arribas Perez, T. Idema, G.H. Koenderink, Biophysical
    Journal 122 (2023) 2311–2324.
date_created: 2024-01-10T09:45:48Z
date_published: 2023-06-06T00:00:00Z
date_updated: 2024-01-16T09:20:03Z
day: '06'
ddc:
- '570'
department:
- _id: AnSa
doi: 10.1016/j.bpj.2023.02.018
external_id:
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  - '001016792600001'
  pmid:
  - '36806830'
file:
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has_accepted_license: '1'
intvolume: '       122'
isi: 1
issue: '11'
keyword:
- Biophysics
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '06'
oa: 1
oa_version: Published Version
page: 2311-2324
pmid: 1
publication: Biophysical Journal
publication_identifier:
  issn:
  - 0006-3495
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/BioSoftMatterGroup/actin-curvature-sensing
status: public
title: Branched actin cortices reconstituted in vesicles sense membrane curvature
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
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  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 122
year: '2023'
...
---
_id: '10145'
abstract:
- lang: eng
  text: We study direct integrals of quadratic and Dirichlet forms. We show that each
    quasi-regular Dirichlet space over a probability space admits a unique representation
    as a direct integral of irreducible Dirichlet spaces, quasi-regular for the same
    underlying topology. The same holds for each quasi-regular strongly local Dirichlet
    space over a metrizable Luzin σ-finite Radon measure space, and admitting carré
    du champ operator. In this case, the representation is only projectively unique.
acknowledgement: The author is grateful to Professors Sergio Albeverio and Andreas
  Eberle, and to Dr. Kohei Suzuki, for fruitful conversations on the subject of the
  present work, and for respectively pointing out the references [1, 13], and [3,
  20]. Finally, he is especially grateful to an anonymous Reviewer for their very
  careful reading and their suggestions which improved the readability of the paper.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Lorenzo
  full_name: Dello Schiavo, Lorenzo
  id: ECEBF480-9E4F-11EA-B557-B0823DDC885E
  last_name: Dello Schiavo
  orcid: 0000-0002-9881-6870
citation:
  ama: Dello Schiavo L. Ergodic decomposition of Dirichlet forms via direct integrals
    and applications. <i>Potential Analysis</i>. 2023;58:573-615. doi:<a href="https://doi.org/10.1007/s11118-021-09951-y">10.1007/s11118-021-09951-y</a>
  apa: Dello Schiavo, L. (2023). Ergodic decomposition of Dirichlet forms via direct
    integrals and applications. <i>Potential Analysis</i>. Springer Nature. <a href="https://doi.org/10.1007/s11118-021-09951-y">https://doi.org/10.1007/s11118-021-09951-y</a>
  chicago: Dello Schiavo, Lorenzo. “Ergodic Decomposition of Dirichlet Forms via Direct
    Integrals and Applications.” <i>Potential Analysis</i>. Springer Nature, 2023.
    <a href="https://doi.org/10.1007/s11118-021-09951-y">https://doi.org/10.1007/s11118-021-09951-y</a>.
  ieee: L. Dello Schiavo, “Ergodic decomposition of Dirichlet forms via direct integrals
    and applications,” <i>Potential Analysis</i>, vol. 58. Springer Nature, pp. 573–615,
    2023.
  ista: Dello Schiavo L. 2023. Ergodic decomposition of Dirichlet forms via direct
    integrals and applications. Potential Analysis. 58, 573–615.
  mla: Dello Schiavo, Lorenzo. “Ergodic Decomposition of Dirichlet Forms via Direct
    Integrals and Applications.” <i>Potential Analysis</i>, vol. 58, Springer Nature,
    2023, pp. 573–615, doi:<a href="https://doi.org/10.1007/s11118-021-09951-y">10.1007/s11118-021-09951-y</a>.
  short: L. Dello Schiavo, Potential Analysis 58 (2023) 573–615.
date_created: 2021-10-17T22:01:17Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2023-10-04T09:19:12Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1007/s11118-021-09951-y
ec_funded: 1
external_id:
  arxiv:
  - '2003.01366'
  isi:
  - '000704213400001'
file:
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  checksum: 625526482be300ca7281c91c30d41725
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file_date_updated: 2023-10-04T09:18:59Z
has_accepted_license: '1'
intvolume: '        58'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 573-615
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
publication: Potential Analysis
publication_identifier:
  eissn:
  - 1572-929X
  issn:
  - 0926-2601
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ergodic decomposition of Dirichlet forms via direct integrals and applications
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2023'
...
---
_id: '10173'
abstract:
- lang: eng
  text: We study the large scale behavior of elliptic systems with stationary random
    coefficient that have only slowly decaying correlations. To this aim we analyze
    the so-called corrector equation, a degenerate elliptic equation posed in the
    probability space. In this contribution, we use a parabolic approach and optimally
    quantify the time decay of the semigroup. For the theoretical point of view, we
    prove an optimal decay estimate of the gradient and flux of the corrector when
    spatially averaged over a scale R larger than 1. For the numerical point of view,
    our results provide convenient tools for the analysis of various numerical methods.
acknowledgement: "I would like to thank my advisor Antoine Gloria for suggesting this
  problem to me, as well for many interesting discussions and suggestions.\r\nOpen
  access funding provided by Institute of Science and Technology (IST Austria)."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Nicolas
  full_name: Clozeau, Nicolas
  id: fea1b376-906f-11eb-847d-b2c0cf46455b
  last_name: Clozeau
citation:
  ama: 'Clozeau N. Optimal decay of the parabolic semigroup in stochastic homogenization 
    for correlated coefficient fields. <i>Stochastics and Partial Differential Equations:
    Analysis and Computations</i>. 2023;11:1254–1378. doi:<a href="https://doi.org/10.1007/s40072-022-00254-w">10.1007/s40072-022-00254-w</a>'
  apa: 'Clozeau, N. (2023). Optimal decay of the parabolic semigroup in stochastic
    homogenization  for correlated coefficient fields. <i>Stochastics and Partial
    Differential Equations: Analysis and Computations</i>. Springer Nature. <a href="https://doi.org/10.1007/s40072-022-00254-w">https://doi.org/10.1007/s40072-022-00254-w</a>'
  chicago: 'Clozeau, Nicolas. “Optimal Decay of the Parabolic Semigroup in Stochastic
    Homogenization  for Correlated Coefficient Fields.” <i>Stochastics and Partial
    Differential Equations: Analysis and Computations</i>. Springer Nature, 2023.
    <a href="https://doi.org/10.1007/s40072-022-00254-w">https://doi.org/10.1007/s40072-022-00254-w</a>.'
  ieee: 'N. Clozeau, “Optimal decay of the parabolic semigroup in stochastic homogenization 
    for correlated coefficient fields,” <i>Stochastics and Partial Differential Equations:
    Analysis and Computations</i>, vol. 11. Springer Nature, pp. 1254–1378, 2023.'
  ista: 'Clozeau N. 2023. Optimal decay of the parabolic semigroup in stochastic homogenization 
    for correlated coefficient fields. Stochastics and Partial Differential Equations:
    Analysis and Computations. 11, 1254–1378.'
  mla: 'Clozeau, Nicolas. “Optimal Decay of the Parabolic Semigroup in Stochastic
    Homogenization  for Correlated Coefficient Fields.” <i>Stochastics and Partial
    Differential Equations: Analysis and Computations</i>, vol. 11, Springer Nature,
    2023, pp. 1254–1378, doi:<a href="https://doi.org/10.1007/s40072-022-00254-w">10.1007/s40072-022-00254-w</a>.'
  short: 'N. Clozeau, Stochastics and Partial Differential Equations: Analysis and
    Computations 11 (2023) 1254–1378.'
date_created: 2021-10-23T10:50:22Z
date_published: 2023-09-01T00:00:00Z
date_updated: 2023-08-14T11:51:47Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1007/s40072-022-00254-w
external_id:
  arxiv:
  - '2102.07452'
  isi:
  - '000799715600001'
file:
- access_level: open_access
  checksum: f83dcaecdbd3ace862c4ed97a20e8501
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  creator: dernst
  date_created: 2023-08-14T11:51:04Z
  date_updated: 2023-08-14T11:51:04Z
  file_id: '14052'
  file_name: 2023_StochPartialDiffEquations_Clozeau.pdf
  file_size: 1635193
  relation: main_file
  success: 1
file_date_updated: 2023-08-14T11:51:04Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1254–1378
publication: 'Stochastics and Partial Differential Equations: Analysis and Computations'
publication_identifier:
  issn:
  - 2194-0401
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optimal decay of the parabolic semigroup in stochastic homogenization  for
  correlated coefficient fields
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2023'
...
