---
_id: '5378'
abstract:
- lang: eng
  text: 'One central issue in the formal design and analysis of reactive systems is
    the notion of refinement that asks whether all behaviors of the implementation
    is allowed by the specification. The local interpretation of behavior leads to
    the notion of simulation. Alternating transition systems (ATSs) provide a general
    model for composite reactive systems, and the simulation relation for ATSs is
    known as alternating simulation. The simulation relation for fair transition systems
    is called fair simulation. In this work our main contributions are as follows:
    (1) We present an improved algorithm for fair simulation with Büchi fairness constraints;
    our algorithm requires O(n3 · m) time as compared to the previous known O(n6)-time
    algorithm, where n is the number of states and m is the number of transitions.
    (2) We present a game based algorithm for alternating simulation that requires
    O(m2)-time as compared to the previous known O((n · m)2)-time algorithm, where
    n is the number of states and m is the size of transition relation. (3) We present
    an iterative algorithm for alternating simulation that matches the time complexity
    of the game based algorithm, but is more space efficient than the game based algorithm.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Siddhesh
  full_name: Chaubal, Siddhesh
  last_name: Chaubal
- first_name: Pritish
  full_name: Kamath, Pritish
  last_name: Kamath
citation:
  ama: Chatterjee K, Chaubal S, Kamath P. <i>Faster Algorithms for Alternating Refinement
    Relations</i>. IST Austria; 2012. doi:<a href="https://doi.org/10.15479/AT:IST-2012-0001">10.15479/AT:IST-2012-0001</a>
  apa: Chatterjee, K., Chaubal, S., &#38; Kamath, P. (2012). <i>Faster algorithms
    for alternating refinement relations</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2012-0001">https://doi.org/10.15479/AT:IST-2012-0001</a>
  chicago: Chatterjee, Krishnendu, Siddhesh Chaubal, and Pritish Kamath. <i>Faster
    Algorithms for Alternating Refinement Relations</i>. IST Austria, 2012. <a href="https://doi.org/10.15479/AT:IST-2012-0001">https://doi.org/10.15479/AT:IST-2012-0001</a>.
  ieee: K. Chatterjee, S. Chaubal, and P. Kamath, <i>Faster algorithms for alternating
    refinement relations</i>. IST Austria, 2012.
  ista: Chatterjee K, Chaubal S, Kamath P. 2012. Faster algorithms for alternating
    refinement relations, IST Austria, 21p.
  mla: Chatterjee, Krishnendu, et al. <i>Faster Algorithms for Alternating Refinement
    Relations</i>. IST Austria, 2012, doi:<a href="https://doi.org/10.15479/AT:IST-2012-0001">10.15479/AT:IST-2012-0001</a>.
  short: K. Chatterjee, S. Chaubal, P. Kamath, Faster Algorithms for Alternating Refinement
    Relations, IST Austria, 2012.
date_created: 2018-12-12T11:38:59Z
date_published: 2012-07-04T00:00:00Z
date_updated: 2023-02-23T12:21:38Z
day: '04'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2012-0001
file:
- access_level: open_access
  checksum: ec8d1857cc7095d3de5107a0162ced37
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:28Z
  date_updated: 2020-07-14T12:46:39Z
  file_id: '5489'
  file_name: IST-2012-0001_IST-2012-0001.pdf
  file_size: 394256
  relation: main_file
file_date_updated: 2020-07-14T12:46:39Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '21'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '14'
related_material:
  record:
  - id: '497'
    relation: later_version
    status: public
status: public
title: Faster algorithms for alternating refinement relations
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5396'
abstract:
- lang: eng
  text: We consider the problem of inference in agraphical model with binary variables.
    While in theory it is arguably preferable to compute marginal probabilities, in
    practice researchers often use MAP inference due to the availability of efficient
    discrete optimization algorithms. We bridge the gap between the two approaches
    by introducing the Discrete  Marginals technique in which approximate marginals
    are obtained by minimizing an objective function with unary and pair-wise terms
    over a discretized domain. This allows the use of techniques originally devel-oped
    for MAP-MRF inference and learning. We explore two ways to set up the objective
    function - by discretizing the Bethe free energy and by learning it  from training
    data. Experimental results show that for certain types of graphs a learned function
    can out-perform the  Bethe approximation. We also establish a link between the
    Bethe free energy and submodular functions.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Filip
  full_name: Korc, Filip
  id: 476A2FD6-F248-11E8-B48F-1D18A9856A87
  last_name: Korc
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: Korc F, Kolmogorov V, Lampert C. <i>Approximating Marginals Using Discrete
    Energy Minimization</i>. IST Austria; 2012. doi:<a href="https://doi.org/10.15479/AT:IST-2012-0003">10.15479/AT:IST-2012-0003</a>
  apa: Korc, F., Kolmogorov, V., &#38; Lampert, C. (2012). <i>Approximating marginals
    using discrete energy minimization</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2012-0003">https://doi.org/10.15479/AT:IST-2012-0003</a>
  chicago: Korc, Filip, Vladimir Kolmogorov, and Christoph Lampert. <i>Approximating
    Marginals Using Discrete Energy Minimization</i>. IST Austria, 2012. <a href="https://doi.org/10.15479/AT:IST-2012-0003">https://doi.org/10.15479/AT:IST-2012-0003</a>.
  ieee: F. Korc, V. Kolmogorov, and C. Lampert, <i>Approximating marginals using discrete
    energy minimization</i>. IST Austria, 2012.
  ista: Korc F, Kolmogorov V, Lampert C. 2012. Approximating marginals using discrete
    energy minimization, IST Austria, 13p.
  mla: Korc, Filip, et al. <i>Approximating Marginals Using Discrete Energy Minimization</i>.
    IST Austria, 2012, doi:<a href="https://doi.org/10.15479/AT:IST-2012-0003">10.15479/AT:IST-2012-0003</a>.
  short: F. Korc, V. Kolmogorov, C. Lampert, Approximating Marginals Using Discrete
    Energy Minimization, IST Austria, 2012.
date_created: 2018-12-12T11:39:06Z
date_published: 2012-07-23T00:00:00Z
date_updated: 2023-02-23T11:13:22Z
day: '23'
ddc:
- '000'
department:
- _id: VlKo
- _id: ChLa
doi: 10.15479/AT:IST-2012-0003
file:
- access_level: open_access
  checksum: 7e0ba85ad123b13223aaf6cdde2d288c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:29Z
  date_updated: 2020-07-14T12:46:44Z
  file_id: '5490'
  file_name: IST-2012-0003_IST-2012-0003.pdf
  file_size: 618744
  relation: main_file
file_date_updated: 2020-07-14T12:46:44Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '13'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '36'
related_material:
  record:
  - id: '3124'
    relation: earlier_version
    status: public
status: public
title: Approximating marginals using discrete energy minimization
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5398'
abstract:
- lang: eng
  text: This document is created as a part of the project “Repository for Research
    Data on IST Austria”. It summarises the actual state of research data at IST Austria,
    based on survey results. It supports the choice of appropriate software, which
    would best fit the requirements of their users, the researchers.
author:
- first_name: Jana
  full_name: Porsche, Jana
  id: 3252EDC2-F248-11E8-B48F-1D18A9856A87
  last_name: Porsche
citation:
  ama: Porsche J. <i>Actual State of Research Data @ ISTAustria</i>. IST Austria;
    2012.
  apa: Porsche, J. (2012). <i>Actual state of research data @ ISTAustria</i>. IST
    Austria.
  chicago: Porsche, Jana. <i>Actual State of Research Data @ ISTAustria</i>. IST Austria,
    2012.
  ieee: J. Porsche, <i>Actual state of research data @ ISTAustria</i>. IST Austria,
    2012.
  ista: Porsche J. 2012. Actual state of research data @ ISTAustria, IST Austria,p.
  mla: Porsche, Jana. <i>Actual State of Research Data @ ISTAustria</i>. IST Austria,
    2012.
  short: J. Porsche, Actual State of Research Data @ ISTAustria, IST Austria, 2012.
date_created: 2018-12-12T11:39:06Z
date_published: 2012-11-12T00:00:00Z
date_updated: 2020-07-14T23:04:49Z
day: '12'
ddc:
- '020'
department:
- _id: E-Lib
file:
- access_level: open_access
  checksum: e0a7c041eea1ca4b70ab6f9ec5177f4e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:11Z
  date_updated: 2020-07-14T12:46:44Z
  file_id: '5472'
  file_name: IST-2012-103-v1+1_Actual_state_of_research_data_@_IST_Austria.pdf
  file_size: 238544
  relation: main_file
file_date_updated: 2020-07-14T12:46:44Z
has_accepted_license: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication_status: published
publisher: IST Austria
pubrep_id: '103'
status: public
title: Actual state of research data @ ISTAustria
type: report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5745'
article_processing_charge: No
author:
- first_name: Ashutosh
  full_name: Gupta, Ashutosh
  last_name: Gupta
citation:
  ama: 'Gupta A. Improved Single Pass Algorithms for Resolution Proof Reduction. In:
    <i>Automated Technology for Verification and Analysis</i>. Vol 7561. LNCS. Berlin,
    Heidelberg: Springer Berlin Heidelberg; 2012:107-121. doi:<a href="https://doi.org/10.1007/978-3-642-33386-6_10">10.1007/978-3-642-33386-6_10</a>'
  apa: 'Gupta, A. (2012). Improved Single Pass Algorithms for Resolution Proof Reduction.
    In <i>Automated Technology for Verification and Analysis</i> (Vol. 7561, pp. 107–121).
    Berlin, Heidelberg: Springer Berlin Heidelberg. <a href="https://doi.org/10.1007/978-3-642-33386-6_10">https://doi.org/10.1007/978-3-642-33386-6_10</a>'
  chicago: 'Gupta, Ashutosh. “Improved Single Pass Algorithms for Resolution Proof
    Reduction.” In <i>Automated Technology for Verification and Analysis</i>, 7561:107–21.
    LNCS. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. <a href="https://doi.org/10.1007/978-3-642-33386-6_10">https://doi.org/10.1007/978-3-642-33386-6_10</a>.'
  ieee: 'A. Gupta, “Improved Single Pass Algorithms for Resolution Proof Reduction,”
    in <i>Automated Technology for Verification and Analysis</i>, vol. 7561, Berlin,
    Heidelberg: Springer Berlin Heidelberg, 2012, pp. 107–121.'
  ista: 'Gupta A. 2012.Improved Single Pass Algorithms for Resolution Proof Reduction.
    In: Automated Technology for Verification and Analysis. vol. 7561, 107–121.'
  mla: Gupta, Ashutosh. “Improved Single Pass Algorithms for Resolution Proof Reduction.”
    <i>Automated Technology for Verification and Analysis</i>, vol. 7561, Springer
    Berlin Heidelberg, 2012, pp. 107–21, doi:<a href="https://doi.org/10.1007/978-3-642-33386-6_10">10.1007/978-3-642-33386-6_10</a>.
  short: A. Gupta, in:, Automated Technology for Verification and Analysis, Springer
    Berlin Heidelberg, Berlin, Heidelberg, 2012, pp. 107–121.
conference:
  end_date: 2012-10-06
  location: Thiruvananthapuram, Kerala, India
  name: ATVA 2012
  start_date: 2012-10-03
date_created: 2018-12-18T13:01:46Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2023-09-05T14:15:29Z
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-33386-6_10
ec_funded: 1
file:
- access_level: open_access
  checksum: 68415837a315de3cc4d120f6019d752c
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-18T13:07:35Z
  date_updated: 2020-07-14T12:47:10Z
  file_id: '5746'
  file_name: 2012_ATVA_Gupta.pdf
  file_size: 465502
  relation: main_file
file_date_updated: 2020-07-14T12:47:10Z
has_accepted_license: '1'
intvolume: '      7561'
language:
- iso: eng
oa: 1
oa_version: None
page: 107-121
place: Berlin, Heidelberg
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
publication: Automated Technology for Verification and Analysis
publication_identifier:
  eissn:
  - 1611-3349
  isbn:
  - '9783642333859'
  - '9783642333866'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Berlin Heidelberg
pubrep_id: '180'
quality_controlled: '1'
series_title: LNCS
status: public
title: Improved Single Pass Algorithms for Resolution Proof Reduction
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 7561
year: '2012'
...
---
_id: '5839'
abstract:
- lang: eng
  text: "Canny's edge detection algorithm is a classical and robust method for edge
    detection in gray-scale images. The two \r\nsignificant features of this method
    are introduction of NMS (Non-Maximum Suppression) and double thresholding of \r\nthe
    \ gradient  image.  Due  to  poor  illumination,  the  region  boundaries  in
    \ an  image  may  become  vague,  creating  \r\nuncertainties  in  the  gradient
    \ image.  In  this  paper,  we  have  proposed  an  algorithm  based  on  the
    \ concept  of  type-2  fuzzy  sets  to  handle  uncertainties  that  automatically
    \ selects  the  threshold  values  needed  to  segment  the  gradient image using
    classical Canny’s edge detection algorithm. The results show that our algorithm
    works significantly well on different benchmark images as well as medical images
    (hand radiography images). "
author:
- first_name: Ranita
  full_name: Biswas, Ranita
  id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
  last_name: Biswas
  orcid: 0000-0002-5372-7890
- first_name: Jaya
  full_name: Sil, Jaya
  last_name: Sil
citation:
  ama: Biswas R, Sil J. An Improved Canny Edge Detection Algorithm Based on Type-2
    Fuzzy Sets. <i>Procedia Technology</i>. 2012;4:820-824. doi:<a href="https://doi.org/10.1016/j.protcy.2012.05.134">10.1016/j.protcy.2012.05.134</a>
  apa: Biswas, R., &#38; Sil, J. (2012). An Improved Canny Edge Detection Algorithm
    Based on Type-2 Fuzzy Sets. <i>Procedia Technology</i>. Elsevier. <a href="https://doi.org/10.1016/j.protcy.2012.05.134">https://doi.org/10.1016/j.protcy.2012.05.134</a>
  chicago: Biswas, Ranita, and Jaya Sil. “An Improved Canny Edge Detection Algorithm
    Based on Type-2 Fuzzy Sets.” <i>Procedia Technology</i>. Elsevier, 2012. <a href="https://doi.org/10.1016/j.protcy.2012.05.134">https://doi.org/10.1016/j.protcy.2012.05.134</a>.
  ieee: R. Biswas and J. Sil, “An Improved Canny Edge Detection Algorithm Based on
    Type-2 Fuzzy Sets,” <i>Procedia Technology</i>, vol. 4. Elsevier, pp. 820–824,
    2012.
  ista: Biswas R, Sil J. 2012. An Improved Canny Edge Detection Algorithm Based on
    Type-2 Fuzzy Sets. Procedia Technology. 4, 820–824.
  mla: Biswas, Ranita, and Jaya Sil. “An Improved Canny Edge Detection Algorithm Based
    on Type-2 Fuzzy Sets.” <i>Procedia Technology</i>, vol. 4, Elsevier, 2012, pp.
    820–24, doi:<a href="https://doi.org/10.1016/j.protcy.2012.05.134">10.1016/j.protcy.2012.05.134</a>.
  short: R. Biswas, J. Sil, Procedia Technology 4 (2012) 820–824.
date_created: 2019-01-17T11:54:21Z
date_published: 2012-05-01T00:00:00Z
date_updated: 2021-01-12T08:03:43Z
day: '01'
ddc:
- '000'
doi: 10.1016/j.protcy.2012.05.134
extern: '1'
file:
- access_level: open_access
  checksum: ba0185986b151d8c11201f48cd505ceb
  content_type: application/pdf
  creator: dernst
  date_created: 2019-01-21T07:28:06Z
  date_updated: 2020-07-14T12:47:12Z
  file_id: '5863'
  file_name: 2012_Procedia_Biswas.pdf
  file_size: 305426
  relation: main_file
file_date_updated: 2020-07-14T12:47:12Z
has_accepted_license: '1'
intvolume: '         4'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 820-824
publication: Procedia Technology
publication_identifier:
  issn:
  - 2212-0173
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: An Improved Canny Edge Detection Algorithm Based on Type-2 Fuzzy Sets
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2012'
...
---
_id: '596'
abstract:
- lang: eng
  text: The human Mediator complex controls RNA polymerase II (pol II) function in
    ways that remain incompletely understood. Activator-Mediator binding alters Mediator
    structure, and these activator-induced structural shifts appear to play key roles
    in regulating transcription. A recent cryo-electron microscopy (EM) analysis revealed
    that pol II adopted a stable orientation within a Mediator-pol II-TFIIF assembly
    in which Mediator was bound to the activation domain of viral protein 16 (VP16).
    Whereas TFIIF was shown to be important for orienting pol II within this assembly,
    the potential role of the activator was not assessed. To determine how activator
    binding might affect pol II orientation, we isolated human Mediator-pol II-TFIIF
    complexes in which Mediator was not bound to an activator. Cryo-EM analysis of
    this assembly, coupled with pol II crystal structure docking, revealed that pol
    II binds Mediator at the same general location; however, in contrast to VP16-bound
    Mediator, pol II does not appear to stably orient in the absence of an activator.
    Variability in pol II orientation might be important mechanistically, perhaps
    to enable sense and antisense transcription at human promoters. Because Mediator
    interacts extensively with pol II, these results suggest that Mediator structural
    shifts induced by activator binding help stably orient pol II prior to transcription
    initiation.
article_processing_charge: No
author:
- first_name: Carrie A
  full_name: Bernecky, Carrie A
  id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
  last_name: Bernecky
  orcid: 0000-0003-0893-7036
- first_name: Dylan
  full_name: Taatjes, Dylan
  last_name: Taatjes
citation:
  ama: Bernecky C, Taatjes D. Activator-mediator binding stabilizes RNA polymerase
    II orientation within the human mediator-RNA polymerase II-TFIIF assembly. <i>Journal
    of Molecular Biology</i>. 2012;417(5):387-394. doi:<a href="https://doi.org/10.1016/j.jmb.2012.02.014">10.1016/j.jmb.2012.02.014</a>
  apa: Bernecky, C., &#38; Taatjes, D. (2012). Activator-mediator binding stabilizes
    RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF
    assembly. <i>Journal of Molecular Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.jmb.2012.02.014">https://doi.org/10.1016/j.jmb.2012.02.014</a>
  chicago: Bernecky, Carrie, and Dylan Taatjes. “Activator-Mediator Binding Stabilizes
    RNA Polymerase II Orientation within the Human Mediator-RNA Polymerase II-TFIIF
    Assembly.” <i>Journal of Molecular Biology</i>. Elsevier, 2012. <a href="https://doi.org/10.1016/j.jmb.2012.02.014">https://doi.org/10.1016/j.jmb.2012.02.014</a>.
  ieee: C. Bernecky and D. Taatjes, “Activator-mediator binding stabilizes RNA polymerase
    II orientation within the human mediator-RNA polymerase II-TFIIF assembly,” <i>Journal
    of Molecular Biology</i>, vol. 417, no. 5. Elsevier, pp. 387–394, 2012.
  ista: Bernecky C, Taatjes D. 2012. Activator-mediator binding stabilizes RNA polymerase
    II orientation within the human mediator-RNA polymerase II-TFIIF assembly. Journal
    of Molecular Biology. 417(5), 387–394.
  mla: Bernecky, Carrie, and Dylan Taatjes. “Activator-Mediator Binding Stabilizes
    RNA Polymerase II Orientation within the Human Mediator-RNA Polymerase II-TFIIF
    Assembly.” <i>Journal of Molecular Biology</i>, vol. 417, no. 5, Elsevier, 2012,
    pp. 387–94, doi:<a href="https://doi.org/10.1016/j.jmb.2012.02.014">10.1016/j.jmb.2012.02.014</a>.
  short: C. Bernecky, D. Taatjes, Journal of Molecular Biology 417 (2012) 387–394.
date_created: 2018-12-11T11:47:24Z
date_published: 2012-04-13T00:00:00Z
date_updated: 2021-01-12T08:05:21Z
day: '13'
doi: 10.1016/j.jmb.2012.02.014
extern: '1'
intvolume: '       417'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582759/
month: '04'
oa: 1
oa_version: None
page: 387 - 394
publication: Journal of Molecular Biology
publication_status: published
publisher: Elsevier
publist_id: '7208'
status: public
title: Activator-mediator binding stabilizes RNA polymerase II orientation within
  the human mediator-RNA polymerase II-TFIIF assembly
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 417
year: '2012'
...
---
_id: '6136'
abstract:
- lang: eng
  text: Tonic receptors convey stimulus duration and intensity and are implicated
    in homeostatic control. However, how tonic homeostatic signals are generated and
    how they reconfigure neural circuits and modify animal behavior is poorly understood.
    Here we show that Caenorhabditis elegans O2-sensing neurons are tonic receptors
    that continuously signal ambient [O2] to set the animal's behavioral state. Sustained
    signaling relied on a Ca2+ relay involving L-type voltage-gated Ca2+ channels,
    the ryanodine and the inositol-1,4,5-trisphosphate receptors. Tonic activity evoked
    continuous neuropeptide release, which helps elicit the enduring behavioral state
    associated with high [O2]. Sustained O2 receptor signaling was propagated to downstream
    neural circuits, including the hub interneuron RMG. O2 receptors evoked similar
    locomotory states at particular O2 concentrations, regardless of previous d[O2]/dt.
    However, a phasic component of the URX receptors' response to high d[O2]/dt, as
    well as tonic-to-phasic transformations in downstream interneurons, enabled transient
    reorientation movements shaped by d[O2]/dt. Our results highlight how tonic homeostatic
    signals can generate both transient and enduring behavioral change.
author:
- first_name: Karl Emanuel
  full_name: Busch, Karl Emanuel
  last_name: Busch
- first_name: Patrick
  full_name: Laurent, Patrick
  last_name: Laurent
- first_name: Zoltan
  full_name: Soltesz, Zoltan
  last_name: Soltesz
- first_name: Robin Joseph
  full_name: Murphy, Robin Joseph
  last_name: Murphy
- first_name: Olivier
  full_name: Faivre, Olivier
  last_name: Faivre
- first_name: Berthold
  full_name: Hedwig, Berthold
  last_name: Hedwig
- first_name: Martin
  full_name: Thomas, Martin
  last_name: Thomas
- first_name: Heather L
  full_name: Smith, Heather L
  last_name: Smith
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
citation:
  ama: Busch KE, Laurent P, Soltesz Z, et al. Tonic signaling from O2 sensors sets
    neural circuit activity and behavioral state. <i>Nature Neuroscience</i>. 2012;15(4):581-591.
    doi:<a href="https://doi.org/10.1038/nn.3061">10.1038/nn.3061</a>
  apa: Busch, K. E., Laurent, P., Soltesz, Z., Murphy, R. J., Faivre, O., Hedwig,
    B., … de Bono, M. (2012). Tonic signaling from O2 sensors sets neural circuit
    activity and behavioral state. <i>Nature Neuroscience</i>. Springer Nature. <a
    href="https://doi.org/10.1038/nn.3061">https://doi.org/10.1038/nn.3061</a>
  chicago: Busch, Karl Emanuel, Patrick Laurent, Zoltan Soltesz, Robin Joseph Murphy,
    Olivier Faivre, Berthold Hedwig, Martin Thomas, Heather L Smith, and Mario de
    Bono. “Tonic Signaling from O2 Sensors Sets Neural Circuit Activity and Behavioral
    State.” <i>Nature Neuroscience</i>. Springer Nature, 2012. <a href="https://doi.org/10.1038/nn.3061">https://doi.org/10.1038/nn.3061</a>.
  ieee: K. E. Busch <i>et al.</i>, “Tonic signaling from O2 sensors sets neural circuit
    activity and behavioral state,” <i>Nature Neuroscience</i>, vol. 15, no. 4. Springer
    Nature, pp. 581–591, 2012.
  ista: Busch KE, Laurent P, Soltesz Z, Murphy RJ, Faivre O, Hedwig B, Thomas M, Smith
    HL, de Bono M. 2012. Tonic signaling from O2 sensors sets neural circuit activity
    and behavioral state. Nature Neuroscience. 15(4), 581–591.
  mla: Busch, Karl Emanuel, et al. “Tonic Signaling from O2 Sensors Sets Neural Circuit
    Activity and Behavioral State.” <i>Nature Neuroscience</i>, vol. 15, no. 4, Springer
    Nature, 2012, pp. 581–91, doi:<a href="https://doi.org/10.1038/nn.3061">10.1038/nn.3061</a>.
  short: K.E. Busch, P. Laurent, Z. Soltesz, R.J. Murphy, O. Faivre, B. Hedwig, M.
    Thomas, H.L. Smith, M. de Bono, Nature Neuroscience 15 (2012) 581–591.
date_created: 2019-03-20T14:23:30Z
date_published: 2012-03-04T00:00:00Z
date_updated: 2021-01-12T08:06:17Z
day: '04'
doi: 10.1038/nn.3061
extern: '1'
external_id:
  pmid:
  - '22388961'
intvolume: '        15'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564487/
month: '03'
oa: 1
oa_version: Submitted Version
page: 581-591
pmid: 1
publication: Nature Neuroscience
publication_identifier:
  issn:
  - 1097-6256
  - 1546-1726
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Tonic signaling from O2 sensors sets neural circuit activity and behavioral
  state
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2012'
...
---
_id: '6588'
abstract:
- lang: eng
  text: First we note that the best polynomial approximation to vertical bar x vertical
    bar on the set, which consists of an interval on the positive half-axis and a
    point on the negative half-axis, can be given by means of the classical Chebyshev
    polynomials. Then we explore the cases when a solution of the related problem
    on two intervals can be given in elementary functions.
acknowledgement: "This work is supported by the Austrian Science Fund (FWF), Project
  P22025-N18.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Florian
  full_name: Pausinger, Florian
  id: 2A77D7A2-F248-11E8-B48F-1D18A9856A87
  last_name: Pausinger
  orcid: 0000-0002-8379-3768
citation:
  ama: Pausinger F. Elementary solutions of the Bernstein problem on two intervals.
    <i>Journal of Mathematical Physics, Analysis, Geometry</i>. 2012;8(1):63-78.
  apa: Pausinger, F. (2012). Elementary solutions of the Bernstein problem on two
    intervals. <i>Journal of Mathematical Physics, Analysis, Geometry</i>. B. Verkin
    Institute for Low Temperature Physics and Engineering.
  chicago: Pausinger, Florian. “Elementary Solutions of the Bernstein Problem on Two
    Intervals.” <i>Journal of Mathematical Physics, Analysis, Geometry</i>. B. Verkin
    Institute for Low Temperature Physics and Engineering, 2012.
  ieee: F. Pausinger, “Elementary solutions of the Bernstein problem on two intervals,”
    <i>Journal of Mathematical Physics, Analysis, Geometry</i>, vol. 8, no. 1. B.
    Verkin Institute for Low Temperature Physics and Engineering, pp. 63–78, 2012.
  ista: Pausinger F. 2012. Elementary solutions of the Bernstein problem on two intervals.
    Journal of Mathematical Physics, Analysis, Geometry. 8(1), 63–78.
  mla: Pausinger, Florian. “Elementary Solutions of the Bernstein Problem on Two Intervals.”
    <i>Journal of Mathematical Physics, Analysis, Geometry</i>, vol. 8, no. 1, B.
    Verkin Institute for Low Temperature Physics and Engineering, 2012, pp. 63–78.
  short: F. Pausinger, Journal of Mathematical Physics, Analysis, Geometry 8 (2012)
    63–78.
date_created: 2019-06-27T08:16:56Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2023-10-16T09:41:31Z
day: '01'
department:
- _id: HeEd
external_id:
  isi:
  - '000301173600004'
intvolume: '         8'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://mi.mathnet.ru/eng/jmag525
month: '01'
oa: 1
oa_version: Published Version
page: 63-78
publication: Journal of Mathematical Physics, Analysis, Geometry
publication_identifier:
  issn:
  - 1812-9471
publication_status: published
publisher: B. Verkin Institute for Low Temperature Physics and Engineering
quality_controlled: '1'
scopus_import: '1'
status: public
title: Elementary solutions of the Bernstein problem on two intervals
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2012'
...
---
_id: '1471'
abstract:
- lang: eng
  text: 'Given a possibly reducible and non-reduced spectral cover π: X → C over a
    smooth projective complex curve C we determine the group of connected components
    of the Prym variety Prym(X/C). As an immediate application we show that the finite
    group of n-torsion points of the Jacobian of C acts trivially on the cohomology
    of the twisted SL n-Higgs moduli space up to the degree which is predicted by
    topological mirror symmetry. In particular this yields a new proof of a result
    of Harder-Narasimhan, showing that this finite group acts trivially on the cohomology
    of the twisted SL n stable bundle moduli space.'
author:
- first_name: Tamas
  full_name: Tamas Hausel
  id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
  last_name: Hausel
- first_name: Christian
  full_name: Pauly, Christian
  last_name: Pauly
citation:
  ama: Hausel T, Pauly C. Prym varieties of spectral covers. <i>Geometry and Topology</i>.
    2012;16(3):1609-1638. doi:<a href="https://doi.org/10.2140/gt.2012.16.1609">10.2140/gt.2012.16.1609</a>
  apa: Hausel, T., &#38; Pauly, C. (2012). Prym varieties of spectral covers. <i>Geometry
    and Topology</i>. University of Warwick. <a href="https://doi.org/10.2140/gt.2012.16.1609">https://doi.org/10.2140/gt.2012.16.1609</a>
  chicago: Hausel, Tamás, and Christian Pauly. “Prym Varieties of Spectral Covers.”
    <i>Geometry and Topology</i>. University of Warwick, 2012. <a href="https://doi.org/10.2140/gt.2012.16.1609">https://doi.org/10.2140/gt.2012.16.1609</a>.
  ieee: T. Hausel and C. Pauly, “Prym varieties of spectral covers,” <i>Geometry and
    Topology</i>, vol. 16, no. 3. University of Warwick, pp. 1609–1638, 2012.
  ista: Hausel T, Pauly C. 2012. Prym varieties of spectral covers. Geometry and Topology.
    16(3), 1609–1638.
  mla: Hausel, Tamás, and Christian Pauly. “Prym Varieties of Spectral Covers.” <i>Geometry
    and Topology</i>, vol. 16, no. 3, University of Warwick, 2012, pp. 1609–38, doi:<a
    href="https://doi.org/10.2140/gt.2012.16.1609">10.2140/gt.2012.16.1609</a>.
  short: T. Hausel, C. Pauly, Geometry and Topology 16 (2012) 1609–1638.
date_created: 2018-12-11T11:52:13Z
date_published: 2012-08-01T00:00:00Z
date_updated: 2021-01-12T06:50:58Z
day: '01'
doi: 10.2140/gt.2012.16.1609
extern: 1
intvolume: '        16'
issue: '3'
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1012.4748
month: '08'
oa: 1
page: 1609 - 1638
publication: Geometry and Topology
publication_status: published
publisher: University of Warwick
publist_id: '5726'
quality_controlled: 0
status: public
title: Prym varieties of spectral covers
type: journal_article
volume: 16
year: '2012'
...
---
_id: '1472'
abstract:
- lang: eng
  text: For G = GL 2, PGL 2, SL 2 we prove that the perverse filtration associated
    with the Hitchin map on the rational cohomology of the moduli space of twisted
    G-Higgs bundles on a compact Riemann surface C agrees with the weight filtration
    on the rational cohomology of the twisted G character variety of C when the cohomologies
    are identified via non-Abelian Hodge theory. The proof is accomplished by means
    of a study of the topology of the Hitchin map over the locus of integral spectral
    curves.
acknowledgement: Mark Andrea A. de Cataldo was partially supported by N.S.A. and N.S.F.
  Tamás Hausel was supported by a Royal Society University Research Fellowship. Luca
  Migliorini was partially supported by PRIN 2007 project "Spazi di moduli e teoria
  di Lie"
author:
- first_name: Mark
  full_name: De Cataldo, Mark A
  last_name: De Cataldo
- first_name: Tamas
  full_name: Tamas Hausel
  id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
  last_name: Hausel
- first_name: Luca
  full_name: Migliorini, Luca
  last_name: Migliorini
citation:
  ama: 'De Cataldo M, Hausel T, Migliorini L. Topology of hitchin systems and Hodge
    theory of character varieties: The case A 1. <i>Annals of Mathematics</i>. 2012;175(3):1329-1407.
    doi:<a href="https://doi.org/10.4007/annals.2012.175.3.7">10.4007/annals.2012.175.3.7</a>'
  apa: 'De Cataldo, M., Hausel, T., &#38; Migliorini, L. (2012). Topology of hitchin
    systems and Hodge theory of character varieties: The case A 1. <i>Annals of Mathematics</i>.
    Princeton University Press. <a href="https://doi.org/10.4007/annals.2012.175.3.7">https://doi.org/10.4007/annals.2012.175.3.7</a>'
  chicago: 'De Cataldo, Mark, Tamás Hausel, and Luca Migliorini. “Topology of Hitchin
    Systems and Hodge Theory of Character Varieties: The Case A 1.” <i>Annals of Mathematics</i>.
    Princeton University Press, 2012. <a href="https://doi.org/10.4007/annals.2012.175.3.7">https://doi.org/10.4007/annals.2012.175.3.7</a>.'
  ieee: 'M. De Cataldo, T. Hausel, and L. Migliorini, “Topology of hitchin systems
    and Hodge theory of character varieties: The case A 1,” <i>Annals of Mathematics</i>,
    vol. 175, no. 3. Princeton University Press, pp. 1329–1407, 2012.'
  ista: 'De Cataldo M, Hausel T, Migliorini L. 2012. Topology of hitchin systems and
    Hodge theory of character varieties: The case A 1. Annals of Mathematics. 175(3),
    1329–1407.'
  mla: 'De Cataldo, Mark, et al. “Topology of Hitchin Systems and Hodge Theory of
    Character Varieties: The Case A 1.” <i>Annals of Mathematics</i>, vol. 175, no.
    3, Princeton University Press, 2012, pp. 1329–407, doi:<a href="https://doi.org/10.4007/annals.2012.175.3.7">10.4007/annals.2012.175.3.7</a>.'
  short: M. De Cataldo, T. Hausel, L. Migliorini, Annals of Mathematics 175 (2012)
    1329–1407.
date_created: 2018-12-11T11:52:13Z
date_published: 2012-05-01T00:00:00Z
date_updated: 2021-01-12T06:50:59Z
day: '01'
doi: 10.4007/annals.2012.175.3.7
extern: 1
intvolume: '       175'
issue: '3'
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1004.1420
month: '05'
oa: 1
page: 1329 - 1407
publication: Annals of Mathematics
publication_status: published
publisher: Princeton University Press
publist_id: '5727'
quality_controlled: 0
status: public
title: 'Topology of hitchin systems and Hodge theory of character varieties: The case
  A 1'
type: journal_article
volume: 175
year: '2012'
...
---
_id: '13075'
abstract:
- lang: eng
  text: Little is known about the stability of trophic relationships in complex natural
    communities over evolutionary timescales. Here, we use sequence data from 18 nuclear
    loci to reconstruct and compare the intraspecific histories of major Pleistocene
    refugial populations in the Middle East, the Balkans and Iberia in a guild of
    four Chalcid parasitoids (Cecidostiba fungosa, C. semifascia, Hobbya stenonota
    and Mesopolobus amaenus) all attacking Cynipid oak galls. We develop a likelihood
    method to numerically estimate models of divergence between three populations
    from multilocus data. We investigate the power of this framework on simulated
    data, and - using triplet alignments of intronic loci - quantify the support for
    all possible divergence relationships between refugial populations in the four
    parasitoids. Although an East to West order of population divergence has highest
    support in all but one species, we cannot rule out alternative population tree
    topologies. Comparing the estimated times of population splits between species,
    we find that one species, M. amaenus, has a significantly older history than the
    rest of the guild and must have arrived in central Europe at least one glacial
    cycle prior to other guild members. This suggests that although all four species
    may share a common origin in the East, they expanded westwards into Europe at
    different times.
article_processing_charge: No
author:
- first_name: Konrad
  full_name: Lohse, Konrad
  last_name: Lohse
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Graham
  full_name: Stone, Graham
  last_name: Stone
- first_name: George
  full_name: Melika, George
  last_name: Melika
citation:
  ama: 'Lohse K, Barton NH, Stone G, Melika G. Data from: A likelihood-based comparison
    of population histories in a parasitoid guild. 2012. doi:<a href="https://doi.org/10.5061/DRYAD.0G0FS">10.5061/DRYAD.0G0FS</a>'
  apa: 'Lohse, K., Barton, N. H., Stone, G., &#38; Melika, G. (2012). Data from: A
    likelihood-based comparison of population histories in a parasitoid guild. Dryad.
    <a href="https://doi.org/10.5061/DRYAD.0G0FS">https://doi.org/10.5061/DRYAD.0G0FS</a>'
  chicago: 'Lohse, Konrad, Nicholas H Barton, Graham Stone, and George Melika. “Data
    from: A Likelihood-Based Comparison of Population Histories in a Parasitoid Guild.”
    Dryad, 2012. <a href="https://doi.org/10.5061/DRYAD.0G0FS">https://doi.org/10.5061/DRYAD.0G0FS</a>.'
  ieee: 'K. Lohse, N. H. Barton, G. Stone, and G. Melika, “Data from: A likelihood-based
    comparison of population histories in a parasitoid guild.” Dryad, 2012.'
  ista: 'Lohse K, Barton NH, Stone G, Melika G. 2012. Data from: A likelihood-based
    comparison of population histories in a parasitoid guild, Dryad, <a href="https://doi.org/10.5061/DRYAD.0G0FS">10.5061/DRYAD.0G0FS</a>.'
  mla: 'Lohse, Konrad, et al. <i>Data from: A Likelihood-Based Comparison of Population
    Histories in a Parasitoid Guild</i>. Dryad, 2012, doi:<a href="https://doi.org/10.5061/DRYAD.0G0FS">10.5061/DRYAD.0G0FS</a>.'
  short: K. Lohse, N.H. Barton, G. Stone, G. Melika, (2012).
date_created: 2023-05-23T17:01:02Z
date_published: 2012-06-08T00:00:00Z
date_updated: 2025-05-28T11:56:58Z
day: '08'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5061/DRYAD.0G0FS
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.0g0fs
month: '06'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '2968'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: A likelihood-based comparison of population histories in a parasitoid
  guild'
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '1384'
abstract:
- lang: eng
  text: 'Software model checking, as an undecidable problem, has three possible outcomes:
    (1) the program satisfies the specification, (2) the program does not satisfy
    the specification, and (3) the model checker fails. The third outcome usually
    manifests itself in a space-out, time-out, or one component of the verification
    tool giving up; in all of these failing cases, significant computation is performed
    by the verification tool before the failure, but no result is reported. We propose
    to reformulate the model-checking problem as follows, in order to have the verification
    tool report a summary of the performed work even in case of failure: given a program
    and a specification, the model checker returns a condition Ψ - usually a state
    predicate - such that the program satisfies the specification under the condition
    Ψ - that is, as long as the program does not leave the states in which Ψ is satisfied.
    In our experiments, we investigated as one major application of conditional model
    checking the sequential combination of model checkers with information passing.
    We give the condition that one model checker produces, as input to a second conditional
    model checker, such that the verification problem for the second is restricted
    to the part of the state space that is not covered by the condition, i.e., the
    second model checker works on the problems that the first model checker could
    not solve. Our experiments demonstrate that repeated application of conditional
    model checkers, passing information from one model checker to the next, can significantly
    improve the verification results and performance, i.e., we can now verify programs
    that we could not verify before.'
acknowledgement: This  research  was  supported  by  the  Canadian  NSERC grant   RGPIN   341819-07,    the   ERC   Advanced   Grant
  QUAREM, and the Austrian Science Fund NFN RiSE.
article_number: '57'
author:
- first_name: Dirk
  full_name: Beyer, Dirk
  last_name: Beyer
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Mehmet
  full_name: Keremoglu, Mehmet
  last_name: Keremoglu
- first_name: Philipp
  full_name: Wendler, Philipp
  last_name: Wendler
citation:
  ama: 'Beyer D, Henzinger TA, Keremoglu M, Wendler P. Conditional model checking:
    A technique to pass information between verifiers. In: <i>Proceedings of the ACM
    SIGSOFT 20th International Symposium on the Foundations of Software Engineering</i>.
    ACM; 2012. doi:<a href="https://doi.org/10.1145/2393596.2393664">10.1145/2393596.2393664</a>'
  apa: 'Beyer, D., Henzinger, T. A., Keremoglu, M., &#38; Wendler, P. (2012). Conditional
    model checking: A technique to pass information between verifiers. In <i>Proceedings
    of the ACM SIGSOFT 20th International Symposium on the Foundations of Software
    Engineering</i>. Cary, NC, USA: ACM. <a href="https://doi.org/10.1145/2393596.2393664">https://doi.org/10.1145/2393596.2393664</a>'
  chicago: 'Beyer, Dirk, Thomas A Henzinger, Mehmet Keremoglu, and Philipp Wendler.
    “Conditional Model Checking: A Technique to Pass Information between Verifiers.”
    In <i>Proceedings of the ACM SIGSOFT 20th International Symposium on the Foundations
    of Software Engineering</i>. ACM, 2012. <a href="https://doi.org/10.1145/2393596.2393664">https://doi.org/10.1145/2393596.2393664</a>.'
  ieee: 'D. Beyer, T. A. Henzinger, M. Keremoglu, and P. Wendler, “Conditional model
    checking: A technique to pass information between verifiers,” in <i>Proceedings
    of the ACM SIGSOFT 20th International Symposium on the Foundations of Software
    Engineering</i>, Cary, NC, USA, 2012.'
  ista: 'Beyer D, Henzinger TA, Keremoglu M, Wendler P. 2012. Conditional model checking:
    A technique to pass information between verifiers. Proceedings of the ACM SIGSOFT
    20th International Symposium on the Foundations of Software Engineering. FSE:
    Foundations of Software Engineering, 57.'
  mla: 'Beyer, Dirk, et al. “Conditional Model Checking: A Technique to Pass Information
    between Verifiers.” <i>Proceedings of the ACM SIGSOFT 20th International Symposium
    on the Foundations of Software Engineering</i>, 57, ACM, 2012, doi:<a href="https://doi.org/10.1145/2393596.2393664">10.1145/2393596.2393664</a>.'
  short: D. Beyer, T.A. Henzinger, M. Keremoglu, P. Wendler, in:, Proceedings of the
    ACM SIGSOFT 20th International Symposium on the Foundations of Software Engineering,
    ACM, 2012.
conference:
  end_date: 2012-11-16
  location: Cary, NC, USA
  name: 'FSE: Foundations of Software Engineering'
  start_date: 2012-11-11
date_created: 2018-12-11T11:51:42Z
date_published: 2012-11-01T00:00:00Z
date_updated: 2021-01-12T06:50:18Z
day: '01'
department:
- _id: ToHe
doi: 10.1145/2393596.2393664
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1109.6926
month: '11'
oa: 1
oa_version: Preprint
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
publication: Proceedings of the ACM SIGSOFT 20th International Symposium on the Foundations
  of Software Engineering
publication_status: published
publisher: ACM
publist_id: '5826'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Conditional model checking: A technique to pass information between verifiers'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '9014'
abstract:
- lang: eng
  text: In this Letter, we explore experimentally the phase behavior of a dense active
    suspension of self-propelled colloids. In addition to a solidlike and gaslike
    phase observed for high and low densities, a novel cluster phase is reported at
    intermediate densities. This takes the form of a stationary assembly of dense
    aggregates—resulting from a permanent dynamical merging and separation of active
    colloids—whose average size grows with activity as a linear function of the self-propelling
    velocity. While different possible scenarios can be considered to account for
    these observations—such as a generic velocity weakening instability recently put
    forward—we show that the experimental results are reproduced mathematically by
    a chemotactic aggregation mechanism, originally introduced to account for bacterial
    aggregation and accounting here for diffusiophoretic chemical interaction between
    colloidal swimmers.
article_number: '268303'
article_processing_charge: No
article_type: letter_note
arxiv: 1
author:
- first_name: I.
  full_name: Theurkauff, I.
  last_name: Theurkauff
- first_name: C.
  full_name: Cottin-Bizonne, C.
  last_name: Cottin-Bizonne
- first_name: Jérémie A
  full_name: Palacci, Jérémie A
  id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
  last_name: Palacci
  orcid: 0000-0002-7253-9465
- first_name: C.
  full_name: Ybert, C.
  last_name: Ybert
- first_name: L.
  full_name: Bocquet, L.
  last_name: Bocquet
citation:
  ama: Theurkauff I, Cottin-Bizonne C, Palacci JA, Ybert C, Bocquet L. Dynamic clustering
    in active colloidal suspensions with chemical signaling. <i>Physical Review Letters</i>.
    2012;108(26). doi:<a href="https://doi.org/10.1103/physrevlett.108.268303">10.1103/physrevlett.108.268303</a>
  apa: Theurkauff, I., Cottin-Bizonne, C., Palacci, J. A., Ybert, C., &#38; Bocquet,
    L. (2012). Dynamic clustering in active colloidal suspensions with chemical signaling.
    <i>Physical Review Letters</i>. American Physical Society . <a href="https://doi.org/10.1103/physrevlett.108.268303">https://doi.org/10.1103/physrevlett.108.268303</a>
  chicago: Theurkauff, I., C. Cottin-Bizonne, Jérémie A Palacci, C. Ybert, and L.
    Bocquet. “Dynamic Clustering in Active Colloidal Suspensions with Chemical Signaling.”
    <i>Physical Review Letters</i>. American Physical Society , 2012. <a href="https://doi.org/10.1103/physrevlett.108.268303">https://doi.org/10.1103/physrevlett.108.268303</a>.
  ieee: I. Theurkauff, C. Cottin-Bizonne, J. A. Palacci, C. Ybert, and L. Bocquet,
    “Dynamic clustering in active colloidal suspensions with chemical signaling,”
    <i>Physical Review Letters</i>, vol. 108, no. 26. American Physical Society ,
    2012.
  ista: Theurkauff I, Cottin-Bizonne C, Palacci JA, Ybert C, Bocquet L. 2012. Dynamic
    clustering in active colloidal suspensions with chemical signaling. Physical Review
    Letters. 108(26), 268303.
  mla: Theurkauff, I., et al. “Dynamic Clustering in Active Colloidal Suspensions
    with Chemical Signaling.” <i>Physical Review Letters</i>, vol. 108, no. 26, 268303,
    American Physical Society , 2012, doi:<a href="https://doi.org/10.1103/physrevlett.108.268303">10.1103/physrevlett.108.268303</a>.
  short: I. Theurkauff, C. Cottin-Bizonne, J.A. Palacci, C. Ybert, L. Bocquet, Physical
    Review Letters 108 (2012).
date_created: 2021-01-19T10:26:59Z
date_published: 2012-06-29T00:00:00Z
date_updated: 2023-02-23T13:46:45Z
day: '29'
doi: 10.1103/physrevlett.108.268303
extern: '1'
external_id:
  arxiv:
  - '1202.6264'
  pmid:
  - '23005020'
intvolume: '       108'
issue: '26'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1202.6264
month: '06'
oa: 1
oa_version: Preprint
pmid: 1
publication: Physical Review Letters
publication_identifier:
  eissn:
  - '10797114'
  issn:
  - '00319007'
publication_status: published
publisher: 'American Physical Society '
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamic clustering in active colloidal suspensions with chemical signaling
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 108
year: '2012'
...
---
_id: '9142'
abstract:
- lang: eng
  text: "In models of radiative–convective equilibrium it is known that convection
    can spontaneously aggregate into one single localized moist region if the domain
    is large enough. The large changes in the mean climate state and radiative fluxes
    accompanying this self-aggregation raise questions as to what simulations at lower
    resolutions with parameterized convection, in similar homogeneous geometries,
    should be expected to produce to be considered successful in mimicking a cloud-resolving
    model.\r\nThe authors investigate this self-aggregation in a nonrotating, three-dimensional
    cloud-resolving model on a square domain without large-scale forcing. It is found
    that self-aggregation is sensitive not only to the domain size, but also to the
    horizontal resolution. With horizontally homogeneous initial conditions, convective
    aggregation only occurs on domains larger than about 200km and with resolutions
    coarser than about 2km in the model examined. The system exhibits hysteresis,
    so that with aggregated initial conditions, convection remains aggregated even
    at our finest resolution, 500m, as long as the domain is greater than 200–300km.\r\nThe
    sensitivity of self-aggregation to resolution and domain size in this model is
    due to the sensitivity of the distribution of low clouds to these two parameters.
    Indeed, the mechanism responsible for the aggregation of convection is the dynamical
    response to the longwave radiative cooling from low clouds. Strong longwave cooling
    near cloud top in dry regions forces downward motion, which by continuity generates
    inflow near cloud top and near-surface outflow from dry regions. This circulation
    results in the net export of moist static energy from regions with low moist static
    energy, yielding a positive feedback."
article_processing_charge: No
article_type: original
author:
- first_name: Caroline J
  full_name: Muller, Caroline J
  id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
  last_name: Muller
  orcid: 0000-0001-5836-5350
- first_name: Isaac M.
  full_name: Held, Isaac M.
  last_name: Held
citation:
  ama: Muller CJ, Held IM. Detailed investigation of the self-aggregation of convection
    in cloud-resolving simulations. <i>Journal of the Atmospheric Sciences</i>. 2012;69(8):2551-2565.
    doi:<a href="https://doi.org/10.1175/jas-d-11-0257.1">10.1175/jas-d-11-0257.1</a>
  apa: Muller, C. J., &#38; Held, I. M. (2012). Detailed investigation of the self-aggregation
    of convection in cloud-resolving simulations. <i>Journal of the Atmospheric Sciences</i>.
    American Meteorological Society. <a href="https://doi.org/10.1175/jas-d-11-0257.1">https://doi.org/10.1175/jas-d-11-0257.1</a>
  chicago: Muller, Caroline J, and Isaac M. Held. “Detailed Investigation of the Self-Aggregation
    of Convection in Cloud-Resolving Simulations.” <i>Journal of the Atmospheric Sciences</i>.
    American Meteorological Society, 2012. <a href="https://doi.org/10.1175/jas-d-11-0257.1">https://doi.org/10.1175/jas-d-11-0257.1</a>.
  ieee: C. J. Muller and I. M. Held, “Detailed investigation of the self-aggregation
    of convection in cloud-resolving simulations,” <i>Journal of the Atmospheric Sciences</i>,
    vol. 69, no. 8. American Meteorological Society, pp. 2551–2565, 2012.
  ista: Muller CJ, Held IM. 2012. Detailed investigation of the self-aggregation of
    convection in cloud-resolving simulations. Journal of the Atmospheric Sciences.
    69(8), 2551–2565.
  mla: Muller, Caroline J., and Isaac M. Held. “Detailed Investigation of the Self-Aggregation
    of Convection in Cloud-Resolving Simulations.” <i>Journal of the Atmospheric Sciences</i>,
    vol. 69, no. 8, American Meteorological Society, 2012, pp. 2551–65, doi:<a href="https://doi.org/10.1175/jas-d-11-0257.1">10.1175/jas-d-11-0257.1</a>.
  short: C.J. Muller, I.M. Held, Journal of the Atmospheric Sciences 69 (2012) 2551–2565.
date_created: 2021-02-15T14:39:03Z
date_published: 2012-08-01T00:00:00Z
date_updated: 2022-01-24T13:49:41Z
day: '01'
doi: 10.1175/jas-d-11-0257.1
extern: '1'
intvolume: '        69'
issue: '8'
keyword:
- Atmospheric Science
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1175/JAS-D-11-0257.1
month: '08'
oa: 1
oa_version: Published Version
page: 2551-2565
publication: Journal of the Atmospheric Sciences
publication_identifier:
  issn:
  - 0022-4928
  - 1520-0469
publication_status: published
publisher: American Meteorological Society
quality_controlled: '1'
status: public
title: Detailed investigation of the self-aggregation of convection in cloud-resolving
  simulations
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 69
year: '2012'
...
---
_id: '922'
abstract:
- lang: eng
  text: 'We study theoretically the morphologies of biological tubes affected by various
    pathologies. When epithelial cells grow, the negative tension produced by their
    division provokes a buckling instability. Several shapes are investigated: varicose,
    dilated, sinuous, or sausagelike. They are all found in pathologies of tracheal,
    renal tubes, or arteries. The final shape depends crucially on the mechanical
    parameters of the tissues: Young''s modulus, wall-to-lumen ratio, homeostatic
    pressure. We argue that since tissues must be in quasistatic mechanical equilibrium,
    abnormal shapes convey information as to what causes the pathology. We calculate
    a phase diagram of tubular instabilities which could be a helpful guide for investigating
    the underlying genetic regulation.'
article_processing_charge: No
arxiv: 1
author:
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Jacques
  full_name: Prost, Jacques
  last_name: Prost
- first_name: Jean
  full_name: Joanny, Jean
  last_name: Joanny
citation:
  ama: Hannezo EB, Prost J, Joanny J. Mechanical instabilities of biological tubes.
    <i>Physical Review Letters</i>. 2012;109(1). doi:<a href="https://doi.org/10.1103/PhysRevLett.109.018101">10.1103/PhysRevLett.109.018101</a>
  apa: Hannezo, E. B., Prost, J., &#38; Joanny, J. (2012). Mechanical instabilities
    of biological tubes. <i>Physical Review Letters</i>. American Physical Society.
    <a href="https://doi.org/10.1103/PhysRevLett.109.018101">https://doi.org/10.1103/PhysRevLett.109.018101</a>
  chicago: Hannezo, Edouard B, Jacques Prost, and Jean Joanny. “Mechanical Instabilities
    of Biological Tubes.” <i>Physical Review Letters</i>. American Physical Society,
    2012. <a href="https://doi.org/10.1103/PhysRevLett.109.018101">https://doi.org/10.1103/PhysRevLett.109.018101</a>.
  ieee: E. B. Hannezo, J. Prost, and J. Joanny, “Mechanical instabilities of biological
    tubes,” <i>Physical Review Letters</i>, vol. 109, no. 1. American Physical Society,
    2012.
  ista: Hannezo EB, Prost J, Joanny J. 2012. Mechanical instabilities of biological
    tubes. Physical Review Letters. 109(1).
  mla: Hannezo, Edouard B., et al. “Mechanical Instabilities of Biological Tubes.”
    <i>Physical Review Letters</i>, vol. 109, no. 1, American Physical Society, 2012,
    doi:<a href="https://doi.org/10.1103/PhysRevLett.109.018101">10.1103/PhysRevLett.109.018101</a>.
  short: E.B. Hannezo, J. Prost, J. Joanny, Physical Review Letters 109 (2012).
date_created: 2018-12-11T11:49:13Z
date_published: 2012-07-03T00:00:00Z
date_updated: 2021-01-12T08:21:56Z
day: '03'
doi: 10.1103/PhysRevLett.109.018101
extern: '1'
external_id:
  arxiv:
  - '1207.1516'
intvolume: '       109'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1207.1516
month: '07'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '6519'
status: public
title: Mechanical instabilities of biological tubes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 109
year: '2012'
...
---
_id: '9451'
abstract:
- lang: eng
  text: The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes
    DNA demethylation before fertilization, but the targeting preferences, mechanism,
    and biological significance of this process remain unclear. Here, we show that
    active DNA demethylation mediated by the DEMETER DNA glycosylase accounts for
    all of the demethylation in the central cell and preferentially targets small,
    AT-rich, and nucleosome-depleted euchromatic transposable elements. The vegetative
    cell, the companion cell of sperm, also undergoes DEMETER-dependent demethylation
    of similar sequences, and lack of DEMETER in vegetative cells causes reduced small
    RNA–directed DNA methylation of transposons in sperm. Our results demonstrate
    that demethylation in companion cells reinforces transposon methylation in plant
    gametes and likely contributes to stable silencing of transposable elements across
    generations.
article_processing_charge: No
article_type: original
author:
- first_name: Christian A.
  full_name: Ibarra, Christian A.
  last_name: Ibarra
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  last_name: Feng
- first_name: Vera K.
  full_name: Schoft, Vera K.
  last_name: Schoft
- first_name: Tzung-Fu
  full_name: Hsieh, Tzung-Fu
  last_name: Hsieh
- first_name: Rie
  full_name: Uzawa, Rie
  last_name: Uzawa
- first_name: Jessica A.
  full_name: Rodrigues, Jessica A.
  last_name: Rodrigues
- first_name: Assaf
  full_name: Zemach, Assaf
  last_name: Zemach
- first_name: Nina
  full_name: Chumak, Nina
  last_name: Chumak
- first_name: Adriana
  full_name: Machlicova, Adriana
  last_name: Machlicova
- first_name: Toshiro
  full_name: Nishimura, Toshiro
  last_name: Nishimura
- first_name: Denisse
  full_name: Rojas, Denisse
  last_name: Rojas
- first_name: Robert L.
  full_name: Fischer, Robert L.
  last_name: Fischer
- first_name: Hisashi
  full_name: Tamaru, Hisashi
  last_name: Tamaru
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Ibarra CA, Feng X, Schoft VK, et al. Active DNA demethylation in plant companion
    cells reinforces transposon methylation in gametes. <i>Science</i>. 2012;337(6100):1360-1364.
    doi:<a href="https://doi.org/10.1126/science.1224839">10.1126/science.1224839</a>
  apa: Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues,
    J. A., … Zilberman, D. (2012). Active DNA demethylation in plant companion cells
    reinforces transposon methylation in gametes. <i>Science</i>. American Association
    for the Advancement of Science. <a href="https://doi.org/10.1126/science.1224839">https://doi.org/10.1126/science.1224839</a>
  chicago: Ibarra, Christian A., Xiaoqi Feng, Vera K. Schoft, Tzung-Fu Hsieh, Rie
    Uzawa, Jessica A. Rodrigues, Assaf Zemach, et al. “Active DNA Demethylation in
    Plant Companion Cells Reinforces Transposon Methylation in Gametes.” <i>Science</i>.
    American Association for the Advancement of Science, 2012. <a href="https://doi.org/10.1126/science.1224839">https://doi.org/10.1126/science.1224839</a>.
  ieee: C. A. Ibarra <i>et al.</i>, “Active DNA demethylation in plant companion cells
    reinforces transposon methylation in gametes,” <i>Science</i>, vol. 337, no. 6100.
    American Association for the Advancement of Science, pp. 1360–1364, 2012.
  ista: Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A,
    Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman
    D. 2012. Active DNA demethylation in plant companion cells reinforces transposon
    methylation in gametes. Science. 337(6100), 1360–1364.
  mla: Ibarra, Christian A., et al. “Active DNA Demethylation in Plant Companion Cells
    Reinforces Transposon Methylation in Gametes.” <i>Science</i>, vol. 337, no. 6100,
    American Association for the Advancement of Science, 2012, pp. 1360–64, doi:<a
    href="https://doi.org/10.1126/science.1224839">10.1126/science.1224839</a>.
  short: C.A. Ibarra, X. Feng, V.K. Schoft, T.-F. Hsieh, R. Uzawa, J.A. Rodrigues,
    A. Zemach, N. Chumak, A. Machlicova, T. Nishimura, D. Rojas, R.L. Fischer, H.
    Tamaru, D. Zilberman, Science 337 (2012) 1360–1364.
date_created: 2021-06-04T07:51:31Z
date_published: 2012-09-14T00:00:00Z
date_updated: 2021-12-14T08:28:51Z
day: '14'
ddc:
- '580'
department:
- _id: DaZi
doi: 10.1126/science.1224839
extern: '1'
external_id:
  pmid:
  - '22984074'
has_accepted_license: '1'
intvolume: '       337'
issue: '6100'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034762/
month: '09'
oa: 1
oa_version: Published Version
page: 1360-1364
pmid: 1
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Active DNA demethylation in plant companion cells reinforces transposon methylation
  in gametes
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 337
year: '2012'
...
---
_id: '9497'
abstract:
- lang: eng
  text: The regulation of eukaryotic chromatin relies on interactions between many
    epigenetic factors, including histone modifications, DNA methylation, and the
    incorporation of histone variants. H2A.Z, one of the most conserved but enigmatic
    histone variants that is enriched at the transcriptional start sites of genes,
    has been implicated in a variety of chromosomal processes. Recently, we reported
    a genome-wide anticorrelation between H2A.Z and DNA methylation, an epigenetic
    hallmark of heterochromatin that has also been found in the bodies of active genes
    in plants and animals. Here, we investigate the basis of this anticorrelation
    using a novel h2a.z loss-of-function line in Arabidopsis thaliana. Through genome-wide
    bisulfite sequencing, we demonstrate that loss of H2A.Z in Arabidopsis has only
    a minor effect on the level or profile of DNA methylation in genes, and we propose
    that the global anticorrelation between DNA methylation and H2A.Z is primarily
    caused by the exclusion of H2A.Z from methylated DNA. RNA sequencing and genomic
    mapping of H2A.Z show that H2A.Z enrichment across gene bodies, rather than at
    the TSS, is correlated with lower transcription levels and higher measures of
    gene responsiveness. Loss of H2A.Z causes misregulation of many genes that are
    disproportionately associated with response to environmental and developmental
    stimuli. We propose that H2A.Z deposition in gene bodies promotes variability
    in levels and patterns of gene expression, and that a major function of genic
    DNA methylation is to exclude H2A.Z from constitutively expressed genes.
article_number: e1002988
article_processing_charge: No
article_type: original
author:
- first_name: Devin
  full_name: Coleman-Derr, Devin
  last_name: Coleman-Derr
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Coleman-Derr D, Zilberman D. Deposition of histone variant H2A.Z within gene
    bodies regulates responsive genes. <i>PLoS Genetics</i>. 2012;8(10). doi:<a href="https://doi.org/10.1371/journal.pgen.1002988">10.1371/journal.pgen.1002988</a>
  apa: Coleman-Derr, D., &#38; Zilberman, D. (2012). Deposition of histone variant
    H2A.Z within gene bodies regulates responsive genes. <i>PLoS Genetics</i>. Public
    Library of Science. <a href="https://doi.org/10.1371/journal.pgen.1002988">https://doi.org/10.1371/journal.pgen.1002988</a>
  chicago: Coleman-Derr, Devin, and Daniel Zilberman. “Deposition of Histone Variant
    H2A.Z within Gene Bodies Regulates Responsive Genes.” <i>PLoS Genetics</i>. Public
    Library of Science, 2012. <a href="https://doi.org/10.1371/journal.pgen.1002988">https://doi.org/10.1371/journal.pgen.1002988</a>.
  ieee: D. Coleman-Derr and D. Zilberman, “Deposition of histone variant H2A.Z within
    gene bodies regulates responsive genes,” <i>PLoS Genetics</i>, vol. 8, no. 10.
    Public Library of Science, 2012.
  ista: Coleman-Derr D, Zilberman D. 2012. Deposition of histone variant H2A.Z within
    gene bodies regulates responsive genes. PLoS Genetics. 8(10), e1002988.
  mla: Coleman-Derr, Devin, and Daniel Zilberman. “Deposition of Histone Variant H2A.Z
    within Gene Bodies Regulates Responsive Genes.” <i>PLoS Genetics</i>, vol. 8,
    no. 10, e1002988, Public Library of Science, 2012, doi:<a href="https://doi.org/10.1371/journal.pgen.1002988">10.1371/journal.pgen.1002988</a>.
  short: D. Coleman-Derr, D. Zilberman, PLoS Genetics 8 (2012).
date_created: 2021-06-07T10:55:27Z
date_published: 2012-10-11T00:00:00Z
date_updated: 2021-12-14T08:29:57Z
day: '11'
department:
- _id: DaZi
doi: 10.1371/journal.pgen.1002988
extern: '1'
external_id:
  pmid:
  - '23071449'
intvolume: '         8'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1371/journal.pgen.1002988
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Genetics
publication_identifier:
  eissn:
  - 1553-7404
  issn:
  - 1553-7390
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Deposition of histone variant H2A.Z within gene bodies regulates responsive
  genes
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 8
year: '2012'
...
---
_id: '9499'
abstract:
- lang: eng
  text: EMBRYONIC FLOWER1 (EMF1) is a plant-specific gene crucial to Arabidopsis vegetative
    development. Loss of function mutants in the EMF1 gene mimic the phenotype caused
    by mutations in Polycomb Group protein (PcG) genes, which encode epigenetic repressors
    that regulate many aspects of eukaryotic development. In Arabidopsis, Polycomb
    Repressor Complex 2 (PRC2), made of PcG proteins, catalyzes trimethylation of
    lysine 27 on histone H3 (H3K27me3) and PRC1-like proteins catalyze H2AK119 ubiquitination.
    Despite functional similarity to PcG proteins, EMF1 lacks sequence homology with
    known PcG proteins; thus, its role in the PcG mechanism is unclear. To study the
    EMF1 functions and its mechanism of action, we performed genome-wide mapping of
    EMF1 binding and H3K27me3 modification sites in Arabidopsis seedlings. The EMF1
    binding pattern is similar to that of H3K27me3 modification on the chromosomal
    and genic level. ChIPOTLe peak finding and clustering analyses both show that
    the highly trimethylated genes also have high enrichment levels of EMF1 binding,
    termed EMF1_K27 genes. EMF1 interacts with regulatory genes, which are silenced
    to allow vegetative growth, and with genes specifying cell fates during growth
    and differentiation. H3K27me3 marks not only these genes but also some genes that
    are involved in endosperm development and maternal effects. Transcriptome analysis,
    coupled with the H3K27me3 pattern, of EMF1_K27 genes in emf1 and PRC2 mutants
    showed that EMF1 represses gene activities via diverse mechanisms and plays a
    novel role in the PcG mechanism.
article_number: e1002512
article_processing_charge: No
article_type: original
author:
- first_name: Sang Yeol
  full_name: Kim, Sang Yeol
  last_name: Kim
- first_name: Jungeun
  full_name: Lee, Jungeun
  last_name: Lee
- first_name: Leor
  full_name: Eshed-Williams, Leor
  last_name: Eshed-Williams
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
- first_name: Z. Renee
  full_name: Sung, Z. Renee
  last_name: Sung
citation:
  ama: Kim SY, Lee J, Eshed-Williams L, Zilberman D, Sung ZR. EMF1 and PRC2 cooperate
    to repress key regulators of Arabidopsis development. <i>PLoS Genetics</i>. 2012;8(3).
    doi:<a href="https://doi.org/10.1371/journal.pgen.1002512">10.1371/journal.pgen.1002512</a>
  apa: Kim, S. Y., Lee, J., Eshed-Williams, L., Zilberman, D., &#38; Sung, Z. R. (2012).
    EMF1 and PRC2 cooperate to repress key regulators of Arabidopsis development.
    <i>PLoS Genetics</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pgen.1002512">https://doi.org/10.1371/journal.pgen.1002512</a>
  chicago: Kim, Sang Yeol, Jungeun Lee, Leor Eshed-Williams, Daniel Zilberman, and
    Z. Renee Sung. “EMF1 and PRC2 Cooperate to Repress Key Regulators of Arabidopsis
    Development.” <i>PLoS Genetics</i>. Public Library of Science, 2012. <a href="https://doi.org/10.1371/journal.pgen.1002512">https://doi.org/10.1371/journal.pgen.1002512</a>.
  ieee: S. Y. Kim, J. Lee, L. Eshed-Williams, D. Zilberman, and Z. R. Sung, “EMF1
    and PRC2 cooperate to repress key regulators of Arabidopsis development,” <i>PLoS
    Genetics</i>, vol. 8, no. 3. Public Library of Science, 2012.
  ista: Kim SY, Lee J, Eshed-Williams L, Zilberman D, Sung ZR. 2012. EMF1 and PRC2
    cooperate to repress key regulators of Arabidopsis development. PLoS Genetics.
    8(3), e1002512.
  mla: Kim, Sang Yeol, et al. “EMF1 and PRC2 Cooperate to Repress Key Regulators of
    Arabidopsis Development.” <i>PLoS Genetics</i>, vol. 8, no. 3, e1002512, Public
    Library of Science, 2012, doi:<a href="https://doi.org/10.1371/journal.pgen.1002512">10.1371/journal.pgen.1002512</a>.
  short: S.Y. Kim, J. Lee, L. Eshed-Williams, D. Zilberman, Z.R. Sung, PLoS Genetics
    8 (2012).
date_created: 2021-06-07T11:07:56Z
date_published: 2012-03-22T00:00:00Z
date_updated: 2021-12-14T08:31:14Z
day: '22'
department:
- _id: DaZi
doi: 10.1371/journal.pgen.1002512
extern: '1'
external_id:
  pmid:
  - '22457632'
intvolume: '         8'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1371/journal.pgen.1002512
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Genetics
publication_identifier:
  eissn:
  - 1553-7404
  issn:
  - 1553-7390
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: EMF1 and PRC2 cooperate to repress key regulators of Arabidopsis development
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 8
year: '2012'
...
---
_id: '9535'
abstract:
- lang: eng
  text: The most well-studied function of DNA methylation in eukaryotic cells is the
    transcriptional silencing of genes and transposons. More recent results showed
    that many eukaryotes methylate the bodies of genes as well and that this methylation
    correlates with transcriptional activity rather than repression. The purpose of
    gene body methylation remains mysterious, but is potentially related to the histone
    variant H2A.Z. Studies in plants and animals have shown that the genome-wide distributions
    of H2A.Z and DNA methylation are strikingly anticorrelated. Furthermore, we and
    other investigators have shown that this relationship is likely to be the result
    of an ancient but unknown mechanism by which DNA methylation prevents the incorporation
    of H2A.Z. Recently, we discovered strong correlations between the presence of
    H2A.Z within gene bodies, the degree to which a gene's expression varies across
    tissue types or environmental conditions, and transcriptional misregulation in
    an h2a.z mutant. We propose that one basal function of gene body methylation is
    the establishment of constitutive expression patterns within housekeeping genes
    by excluding H2A.Z from their bodies.
article_processing_charge: No
article_type: review
author:
- first_name: D.
  full_name: Coleman-Derr, D.
  last_name: Coleman-Derr
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Coleman-Derr D, Zilberman D. DNA methylation, H2A.Z, and the regulation of
    constitutive expression. <i>Cold Spring Harbor Symposia on Quantitative Biology</i>.
    2012;77:147-154. doi:<a href="https://doi.org/10.1101/sqb.2012.77.014944">10.1101/sqb.2012.77.014944</a>
  apa: Coleman-Derr, D., &#38; Zilberman, D. (2012). DNA methylation, H2A.Z, and the
    regulation of constitutive expression. <i>Cold Spring Harbor Symposia on Quantitative
    Biology</i>. Cold Spring Harbor Laboratory Press. <a href="https://doi.org/10.1101/sqb.2012.77.014944">https://doi.org/10.1101/sqb.2012.77.014944</a>
  chicago: Coleman-Derr, D., and Daniel Zilberman. “DNA Methylation, H2A.Z, and the
    Regulation of Constitutive Expression.” <i>Cold Spring Harbor Symposia on Quantitative
    Biology</i>. Cold Spring Harbor Laboratory Press, 2012. <a href="https://doi.org/10.1101/sqb.2012.77.014944">https://doi.org/10.1101/sqb.2012.77.014944</a>.
  ieee: D. Coleman-Derr and D. Zilberman, “DNA methylation, H2A.Z, and the regulation
    of constitutive expression,” <i>Cold Spring Harbor Symposia on Quantitative Biology</i>,
    vol. 77. Cold Spring Harbor Laboratory Press, pp. 147–154, 2012.
  ista: Coleman-Derr D, Zilberman D. 2012. DNA methylation, H2A.Z, and the regulation
    of constitutive expression. Cold Spring Harbor Symposia on Quantitative Biology.
    77, 147–154.
  mla: Coleman-Derr, D., and Daniel Zilberman. “DNA Methylation, H2A.Z, and the Regulation
    of Constitutive Expression.” <i>Cold Spring Harbor Symposia on Quantitative Biology</i>,
    vol. 77, Cold Spring Harbor Laboratory Press, 2012, pp. 147–54, doi:<a href="https://doi.org/10.1101/sqb.2012.77.014944">10.1101/sqb.2012.77.014944</a>.
  short: D. Coleman-Derr, D. Zilberman, Cold Spring Harbor Symposia on Quantitative
    Biology 77 (2012) 147–154.
date_created: 2021-06-08T13:01:23Z
date_published: 2012-12-18T00:00:00Z
date_updated: 2021-12-14T08:33:09Z
day: '18'
department:
- _id: DaZi
doi: 10.1101/sqb.2012.77.014944
extern: '1'
external_id:
  pmid:
  - '23250988'
intvolume: '        77'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/sqb.2012.77.014944
month: '12'
oa: 1
oa_version: Published Version
page: 147-154
pmid: 1
publication: Cold Spring Harbor Symposia on Quantitative Biology
publication_identifier:
  eissn:
  - 1943-4456
  issn:
  - 0091-7451
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: DNA methylation, H2A.Z, and the regulation of constitutive expression
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 77
year: '2012'
...
---
_id: '966'
abstract:
- lang: eng
  text: Motivated by recent experiments on Ba3NiSb2O 9, we investigate possible quantum
    spin liquid ground states for spin S=1 Heisenberg models on the triangular lattice.
    We use variational Monte Carlo techniques to calculate the energies of microscopic
    spin liquid wave functions where spin is represented by three flavors of fermionic
    spinon operators. These energies are compared with the energies of various competing
    three-sublattice ordered states. Our approach shows that the antiferromagnetic
    Heisenberg model with biquadratic term and single-ion anisotropy does not have
    a low-temperature spin liquid phase. However, for an SU(3)-invariant model with
    sufficiently strong ring-exchange terms, we find a paired chiral quantum spin
    liquid with a Fermi surface of deconfined spinons that is stable against all types
    of ordering patterns we considered. We discuss the physics of this exotic spin
    liquid state in relation to the recent experiment and suggest new ways to test
    this scenario.
acknowledgement: We thank Kuang-Ting Chen, Rebecca Flint, Dmitri Ivanov, Z.-X. Liu,
  Tai-Kai Ng, Lara Thompson, Tamás Tóth, and Fa Wang for helpful discussions. T.S.
  is supported by NSF DMR 1005434. P.A.L. is supported by NSF DMR 1104498. S.B. acknowledges
  support from the Swiss National Science Foundation (SNSF).
author:
- first_name: Samuel
  full_name: Bieri, Samuel
  last_name: Bieri
- first_name: Maksym
  full_name: Maksym Serbyn
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
- first_name: Todadri
  full_name: Senthil, Todadri S
  last_name: Senthil
- first_name: Patrick
  full_name: Lee, Patrick
  last_name: Lee
citation:
  ama: Bieri S, Serbyn M, Senthil T, Lee P. Paired chiral spin liquid with a Fermi
    surface in S=1 model on the triangular lattice. <i>Physical Review B - Condensed
    Matter and Materials Physics</i>. 2012;86(22). doi:<a href="https://doi.org/10.1103/PhysRevB.86.224409">10.1103/PhysRevB.86.224409</a>
  apa: Bieri, S., Serbyn, M., Senthil, T., &#38; Lee, P. (2012). Paired chiral spin
    liquid with a Fermi surface in S=1 model on the triangular lattice. <i>Physical
    Review B - Condensed Matter and Materials Physics</i>. American Physical Society.
    <a href="https://doi.org/10.1103/PhysRevB.86.224409">https://doi.org/10.1103/PhysRevB.86.224409</a>
  chicago: Bieri, Samuel, Maksym Serbyn, Todadri Senthil, and Patrick Lee. “Paired
    Chiral Spin Liquid with a Fermi Surface in S=1 Model on the Triangular Lattice.”
    <i>Physical Review B - Condensed Matter and Materials Physics</i>. American Physical
    Society, 2012. <a href="https://doi.org/10.1103/PhysRevB.86.224409">https://doi.org/10.1103/PhysRevB.86.224409</a>.
  ieee: S. Bieri, M. Serbyn, T. Senthil, and P. Lee, “Paired chiral spin liquid with
    a Fermi surface in S=1 model on the triangular lattice,” <i>Physical Review B
    - Condensed Matter and Materials Physics</i>, vol. 86, no. 22. American Physical
    Society, 2012.
  ista: Bieri S, Serbyn M, Senthil T, Lee P. 2012. Paired chiral spin liquid with
    a Fermi surface in S=1 model on the triangular lattice. Physical Review B - Condensed
    Matter and Materials Physics. 86(22).
  mla: Bieri, Samuel, et al. “Paired Chiral Spin Liquid with a Fermi Surface in S=1
    Model on the Triangular Lattice.” <i>Physical Review B - Condensed Matter and
    Materials Physics</i>, vol. 86, no. 22, American Physical Society, 2012, doi:<a
    href="https://doi.org/10.1103/PhysRevB.86.224409">10.1103/PhysRevB.86.224409</a>.
  short: S. Bieri, M. Serbyn, T. Senthil, P. Lee, Physical Review B - Condensed Matter
    and Materials Physics 86 (2012).
date_created: 2018-12-11T11:49:27Z
date_published: 2012-12-13T00:00:00Z
date_updated: 2021-01-12T08:22:18Z
day: '13'
doi: 10.1103/PhysRevB.86.224409
extern: 1
intvolume: '        86'
issue: '22'
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1208.3231
month: '12'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '6431'
quality_controlled: 0
status: public
title: Paired chiral spin liquid with a Fermi surface in S=1 model on the triangular
  lattice
type: journal_article
volume: 86
year: '2012'
...
