---
_id: '9704'
abstract:
- lang: eng
text: Emerging infectious diseases (EIDs) have contributed significantly to the
current biodiversity crisis, leading to widespread epidemics and population loss.
Owing to genetic variation in pathogen virulence, a complete understanding of
species decline requires the accurate identification and characterization of EIDs.
We explore this issue in the Western honeybee, where increasing mortality of populations
in the Northern Hemisphere has caused major concern. Specifically, we investigate
the importance of genetic identity of the main suspect in mortality, deformed
wing virus (DWV), in driving honeybee loss. Using laboratory experiments and a
systematic field survey, we demonstrate that an emerging DWV genotype (DWV-B)
is more virulent than the established DWV genotype (DWV-A) and is widespread in
the landscape. Furthermore, we show in a simple model that colonies infected with
DWV-B collapse sooner than colonies infected with DWV-A. We also identify potential
for rapid DWV evolution by revealing extensive genome-wide recombination in vivo.
The emergence of DWV-B in naive honeybee populations, including via recombination
with DWV-A, could be of significant ecological and economic importance. Our findings
emphasize that knowledge of pathogen genetic identity and diversity is critical
to understanding drivers of species decline.
article_processing_charge: No
author:
- first_name: Dino
full_name: Mcmahon, Dino
last_name: Mcmahon
- first_name: Myrsini
full_name: Natsopoulou, Myrsini
last_name: Natsopoulou
- first_name: Vincent
full_name: Doublet, Vincent
last_name: Doublet
- first_name: Matthias
full_name: Fürst, Matthias
id: 393B1196-F248-11E8-B48F-1D18A9856A87
last_name: Fürst
orcid: 0000-0002-3712-925X
- first_name: Silvio
full_name: Weging, Silvio
last_name: Weging
- first_name: Mark
full_name: Brown, Mark
last_name: Brown
- first_name: Andreas
full_name: Gogol Döring, Andreas
last_name: Gogol Döring
- first_name: Robert
full_name: Paxton, Robert
last_name: Paxton
citation:
ama: 'Mcmahon D, Natsopoulou M, Doublet V, et al. Data from: Elevated virulence
of an emerging viral genotype as a driver of honeybee loss. 2016. doi:10.5061/dryad.cq7t1'
apa: 'Mcmahon, D., Natsopoulou, M., Doublet, V., Fürst, M., Weging, S., Brown, M.,
… Paxton, R. (2016). Data from: Elevated virulence of an emerging viral genotype
as a driver of honeybee loss. Dryad. https://doi.org/10.5061/dryad.cq7t1'
chicago: 'Mcmahon, Dino, Myrsini Natsopoulou, Vincent Doublet, Matthias Fürst, Silvio
Weging, Mark Brown, Andreas Gogol Döring, and Robert Paxton. “Data from: Elevated
Virulence of an Emerging Viral Genotype as a Driver of Honeybee Loss.” Dryad,
2016. https://doi.org/10.5061/dryad.cq7t1.'
ieee: 'D. Mcmahon et al., “Data from: Elevated virulence of an emerging viral
genotype as a driver of honeybee loss.” Dryad, 2016.'
ista: 'Mcmahon D, Natsopoulou M, Doublet V, Fürst M, Weging S, Brown M, Gogol Döring
A, Paxton R. 2016. Data from: Elevated virulence of an emerging viral genotype
as a driver of honeybee loss, Dryad, 10.5061/dryad.cq7t1.'
mla: 'Mcmahon, Dino, et al. Data from: Elevated Virulence of an Emerging Viral
Genotype as a Driver of Honeybee Loss. Dryad, 2016, doi:10.5061/dryad.cq7t1.'
short: D. Mcmahon, M. Natsopoulou, V. Doublet, M. Fürst, S. Weging, M. Brown, A.
Gogol Döring, R. Paxton, (2016).
date_created: 2021-07-23T08:30:38Z
date_published: 2016-05-06T00:00:00Z
date_updated: 2023-02-21T16:54:31Z
day: '06'
department:
- _id: SyCr
doi: 10.5061/dryad.cq7t1
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.cq7t1
month: '05'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '1262'
relation: used_in_publication
status: public
status: public
title: 'Data from: Elevated virulence of an emerging viral genotype as a driver of
honeybee loss'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9710'
abstract:
- lang: eng
text: Much of quantitative genetics is based on the ‘infinitesimal model’, under
which selection has a negligible effect on the genetic variance. This is typically
justified by assuming a very large number of loci with additive effects. However,
it applies even when genes interact, provided that the number of loci is large
enough that selection on each of them is weak relative to random drift. In the
long term, directional selection will change allele frequencies, but even then,
the effects of epistasis on the ultimate change in trait mean due to selection
may be modest. Stabilising selection can maintain many traits close to their optima,
even when the underlying alleles are weakly selected. However, the number of traits
that can be optimised is apparently limited to ~4Ne by the ‘drift load’, and this
is hard to reconcile with the apparent complexity of many organisms. Just as for
the mutation load, this limit can be evaded by a particular form of negative epistasis.
A more robust limit is set by the variance in reproductive success. This suggests
that selection accumulates information most efficiently in the infinitesimal regime,
when selection on individual alleles is weak, and comparable with random drift.
A review of evidence on selection strength suggests that although most variance
in fitness may be because of alleles with large Nes, substantial amounts of adaptation
may be because of alleles in the infinitesimal regime, in which epistasis has
modest effects.
article_processing_charge: No
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Barton NH. Data from: How does epistasis influence the response to selection?
2016. doi:10.5061/dryad.s5s7r'
apa: 'Barton, N. H. (2016). Data from: How does epistasis influence the response
to selection? Dryad. https://doi.org/10.5061/dryad.s5s7r'
chicago: 'Barton, Nicholas H. “Data from: How Does Epistasis Influence the Response
to Selection?” Dryad, 2016. https://doi.org/10.5061/dryad.s5s7r.'
ieee: 'N. H. Barton, “Data from: How does epistasis influence the response to selection?”
Dryad, 2016.'
ista: 'Barton NH. 2016. Data from: How does epistasis influence the response to
selection?, Dryad, 10.5061/dryad.s5s7r.'
mla: 'Barton, Nicholas H. Data from: How Does Epistasis Influence the Response
to Selection? Dryad, 2016, doi:10.5061/dryad.s5s7r.'
short: N.H. Barton, (2016).
date_created: 2021-07-23T11:45:47Z
date_published: 2016-09-23T00:00:00Z
date_updated: 2025-05-28T11:57:03Z
day: '23'
department:
- _id: NiBa
doi: 10.5061/dryad.s5s7r
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.s5s7r
month: '09'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '1199'
relation: used_in_publication
status: public
status: public
title: 'Data from: How does epistasis influence the response to selection?'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '9720'
abstract:
- lang: eng
text: 'Summary: Declining populations of bee pollinators are a cause of concern,
with major repercussions for biodiversity loss and food security. RNA viruses
associated with honeybees represent a potential threat to other insect pollinators,
but the extent of this threat is poorly understood. This study aims to attain
a detailed understanding of the current and ongoing risk of emerging infectious
disease (EID) transmission between managed and wild pollinator species across
a wide range of RNA viruses. Within a structured large-scale national survey across
26 independent sites, we quantify the prevalence and pathogen loads of multiple
RNA viruses in co-occurring managed honeybee (Apis mellifera) and wild bumblebee
(Bombus spp.) populations. We then construct models that compare virus prevalence
between wild and managed pollinators. Multiple RNA viruses associated with honeybees
are widespread in sympatric wild bumblebee populations. Virus prevalence in honeybees
is a significant predictor of virus prevalence in bumblebees, but we remain cautious
in speculating over the principle direction of pathogen transmission. We demonstrate
species-specific differences in prevalence, indicating significant variation in
disease susceptibility or tolerance. Pathogen loads within individual bumblebees
may be high and in the case of at least one RNA virus, prevalence is higher in
wild bumblebees than in managed honeybee populations. Our findings indicate widespread
transmission of RNA viruses between managed and wild bee pollinators, pointing
to an interconnected network of potential disease pressures within and among pollinator
species. In the context of the biodiversity crisis, our study emphasizes the importance
of targeting a wide range of pathogens and defining host associations when considering
potential drivers of population decline.'
article_processing_charge: No
author:
- first_name: Dino
full_name: Mcmahon, Dino
last_name: Mcmahon
- first_name: Matthias
full_name: Fürst, Matthias
id: 393B1196-F248-11E8-B48F-1D18A9856A87
last_name: Fürst
orcid: 0000-0002-3712-925X
- first_name: Jesicca
full_name: Caspar, Jesicca
last_name: Caspar
- first_name: Panagiotis
full_name: Theodorou, Panagiotis
last_name: Theodorou
- first_name: Mark
full_name: Brown, Mark
last_name: Brown
- first_name: Robert
full_name: Paxton, Robert
last_name: Paxton
citation:
ama: 'Mcmahon D, Fürst M, Caspar J, Theodorou P, Brown M, Paxton R. Data from: A
sting in the spit: widespread cross-infection of multiple RNA viruses across wild
and managed bees. 2016. doi:10.5061/dryad.4b565'
apa: 'Mcmahon, D., Fürst, M., Caspar, J., Theodorou, P., Brown, M., & Paxton,
R. (2016). Data from: A sting in the spit: widespread cross-infection of multiple
RNA viruses across wild and managed bees. Dryad. https://doi.org/10.5061/dryad.4b565'
chicago: 'Mcmahon, Dino, Matthias Fürst, Jesicca Caspar, Panagiotis Theodorou, Mark
Brown, and Robert Paxton. “Data from: A Sting in the Spit: Widespread Cross-Infection
of Multiple RNA Viruses across Wild and Managed Bees.” Dryad, 2016. https://doi.org/10.5061/dryad.4b565.'
ieee: 'D. Mcmahon, M. Fürst, J. Caspar, P. Theodorou, M. Brown, and R. Paxton, “Data
from: A sting in the spit: widespread cross-infection of multiple RNA viruses
across wild and managed bees.” Dryad, 2016.'
ista: 'Mcmahon D, Fürst M, Caspar J, Theodorou P, Brown M, Paxton R. 2016. Data
from: A sting in the spit: widespread cross-infection of multiple RNA viruses
across wild and managed bees, Dryad, 10.5061/dryad.4b565.'
mla: 'Mcmahon, Dino, et al. Data from: A Sting in the Spit: Widespread Cross-Infection
of Multiple RNA Viruses across Wild and Managed Bees. Dryad, 2016, doi:10.5061/dryad.4b565.'
short: D. Mcmahon, M. Fürst, J. Caspar, P. Theodorou, M. Brown, R. Paxton, (2016).
date_created: 2021-07-26T09:14:19Z
date_published: 2016-01-22T00:00:00Z
date_updated: 2023-02-23T10:17:25Z
day: '22'
department:
- _id: SyCr
doi: 10.5061/dryad.4b565
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.4b565
month: '01'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '1855'
relation: used_in_publication
status: public
status: public
title: 'Data from: A sting in the spit: widespread cross-infection of multiple RNA
viruses across wild and managed bees'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '983'
abstract:
- lang: eng
text: The half-filled Landau level is expected to be approximately particle-hole
symmetric, which requires an extension of the Halperin-Lee-Read (HLR) theory of
the compressible state observed at this filling. Recent work indicates that, when
particle-hole symmetry is preserved, the composite fermions experience a quantized
π-Berry phase upon winding around the composite Fermi surface, analogous to Dirac
fermions at the surface of a 3D topological insulator. In contrast, the effective
low-energy theory of the composite fermion liquid originally proposed by HLR lacks
particle-hole symmetry and has vanishing Berry phase. In this paper, we explain
how thermoelectric transport measurements can be used to test the Dirac nature
of the composite fermions by quantitatively extracting this Berry phase. First,
we point out that longitudinal thermopower (Seebeck effect) is nonvanishing because
of the unusual nature of particle-hole symmetry in this context and is not sensitive
to the Berry phase. In contrast, we find that off-diagonal thermopower (Nernst
effect) is directly related to the topological structure of the composite Fermi
surface, vanishing for zero Berry phase and taking its maximal value for π Berry
phase. In contrast, in purely electrical transport signatures, the Berry phase
contributions appear as small corrections to a large background signal, making
the Nernst effect a promising diagnostic of the Dirac nature of composite fermions.
acknowledgement: We thank B. I. Halperin, N. Cooper, C. Wang, J. Alicea, and M. Zaletel
for insightful conversations. A. C. P. and M. S. were supported by the Gordon and
Betty Moore Foundation’s EPiQS Initiative through Grant No. GBMF4307. A. V. was
supported by a Simons Investigator grant.
author:
- first_name: Andrew
full_name: Potter, Andrew C
last_name: Potter
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Ashvin
full_name: Vishwanath, Ashvin K
last_name: Vishwanath
citation:
ama: Potter A, Serbyn M, Vishwanath A. Thermoelectric transport signatures of Dirac
composite fermions in the half-filled Landau level. Physical Review X.
2016;6(3). doi:10.1103/PhysRevX.6.031026
apa: Potter, A., Serbyn, M., & Vishwanath, A. (2016). Thermoelectric transport
signatures of Dirac composite fermions in the half-filled Landau level. Physical
Review X. American Physical Society. https://doi.org/10.1103/PhysRevX.6.031026
chicago: Potter, Andrew, Maksym Serbyn, and Ashvin Vishwanath. “Thermoelectric Transport
Signatures of Dirac Composite Fermions in the Half-Filled Landau Level.” Physical
Review X. American Physical Society, 2016. https://doi.org/10.1103/PhysRevX.6.031026.
ieee: A. Potter, M. Serbyn, and A. Vishwanath, “Thermoelectric transport signatures
of Dirac composite fermions in the half-filled Landau level,” Physical Review
X, vol. 6, no. 3. American Physical Society, 2016.
ista: Potter A, Serbyn M, Vishwanath A. 2016. Thermoelectric transport signatures
of Dirac composite fermions in the half-filled Landau level. Physical Review X.
6(3).
mla: Potter, Andrew, et al. “Thermoelectric Transport Signatures of Dirac Composite
Fermions in the Half-Filled Landau Level.” Physical Review X, vol. 6, no.
3, American Physical Society, 2016, doi:10.1103/PhysRevX.6.031026.
short: A. Potter, M. Serbyn, A. Vishwanath, Physical Review X 6 (2016).
date_created: 2018-12-11T11:49:32Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2021-01-12T08:22:25Z
day: '01'
doi: 10.1103/PhysRevX.6.031026
extern: 1
intvolume: ' 6'
issue: '3'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1512.06852
month: '01'
oa: 1
publication: Physical Review X
publication_status: published
publisher: American Physical Society
publist_id: '6417'
quality_controlled: 0
status: public
title: Thermoelectric transport signatures of Dirac composite fermions in the half-filled
Landau level
type: journal_article
volume: 6
year: '2016'
...
---
_id: '984'
abstract:
- lang: eng
text: The entanglement spectrum of the reduced density matrix contains information
beyond the von Neumann entropy and provides unique insights into exotic orders
or critical behavior of quantum systems. Here, we show that strongly disordered
systems in the many-body localized phase have power-law entanglement spectra,
arising from the presence of extensively many local integrals of motion. The power-law
entanglement spectrum distinguishes many-body localized systems from ergodic systems,
as well as from ground states of gapped integrable models or free systems in the
vicinity of scale-invariant critical points. We confirm our results using large-scale
exact diagonalization. In addition, we develop a matrix-product state algorithm
which allows us to access the eigenstates of large systems close to the localization
transition, and discuss general implications of our results for variational studies
of highly excited eigenstates in many-body localized systems.
acknowledgement: We thank M. Stoudenmire and C. Turner for useful discussions. M.
S. was supported by Gordon and Betty Moore Foundation's EPiQS Initiative through
Grant No. GBMF4307. This research was supported in part by the National Science
Foundation under Grant No. NSF PHY11-25915, and by the Swiss National Science Foundation
and Alfred Sloan Foundation (D. A.). This work made use of the facilities of N8
HPC Centre of Excellence, provided and funded by the N8 consortium and EPSRC (Grant
No. EP/K000225/1). The Centre is coordinated by the Universities of Leeds and Manchester.
author:
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Alexios
full_name: Alexios Michailidis
id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
last_name: Michailidis
- first_name: Dmitry
full_name: Abanin, Dmitry A
last_name: Abanin
- first_name: Zlatko
full_name: Papić, Zlatko
last_name: Papić
citation:
ama: Serbyn M, Michailidis A, Abanin D, Papić Z. Power-law entanglement spectrum
in many-body localized phases. Physical Review Letters. 2016;117(16). doi:10.1103/PhysRevLett.117.160601
apa: Serbyn, M., Michailidis, A., Abanin, D., & Papić, Z. (2016). Power-law
entanglement spectrum in many-body localized phases. Physical Review Letters.
American Physical Society. https://doi.org/10.1103/PhysRevLett.117.160601
chicago: Serbyn, Maksym, Alexios Michailidis, Dmitry Abanin, and Zlatko Papić. “Power-Law
Entanglement Spectrum in Many-Body Localized Phases.” Physical Review Letters.
American Physical Society, 2016. https://doi.org/10.1103/PhysRevLett.117.160601.
ieee: M. Serbyn, A. Michailidis, D. Abanin, and Z. Papić, “Power-law entanglement
spectrum in many-body localized phases,” Physical Review Letters, vol.
117, no. 16. American Physical Society, 2016.
ista: Serbyn M, Michailidis A, Abanin D, Papić Z. 2016. Power-law entanglement spectrum
in many-body localized phases. Physical Review Letters. 117(16).
mla: Serbyn, Maksym, et al. “Power-Law Entanglement Spectrum in Many-Body Localized
Phases.” Physical Review Letters, vol. 117, no. 16, American Physical Society,
2016, doi:10.1103/PhysRevLett.117.160601.
short: M. Serbyn, A. Michailidis, D. Abanin, Z. Papić, Physical Review Letters 117
(2016).
date_created: 2018-12-11T11:49:32Z
date_published: 2016-10-16T00:00:00Z
date_updated: 2021-01-12T08:22:25Z
day: '16'
doi: 10.1103/PhysRevLett.117.160601
extern: 1
intvolume: ' 117'
issue: '16'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1605.05737
month: '10'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '6414'
quality_controlled: 0
status: public
title: Power-law entanglement spectrum in many-body localized phases
type: journal_article
volume: 117
year: '2016'
...
---
_id: '985'
abstract:
- lang: eng
text: We report on magnetotransport studies of dual-gated, Bernal-stacked trilayer
graphene (TLG) encapsulated in boron nitride crystals. We observe a quantum Hall
effect staircase which indicates a complete lifting of the 12-fold degeneracy
of the zeroth Landau level. As a function of perpendicular electric field, our
data exhibit a sequence of phase transitions between all integer quantum Hall
states in the filling factor interval -8<ν<0. We develop a theoretical model
and argue that, in contrast to monolayer and bilayer graphene, the observed Landau
level splittings and quantum Hall phase transitions can be understood within a
single-particle picture, but imply the presence of a charge density imbalance
between the inner and outer layers of TLG, even at charge neutrality and zero
transverse electric field. Our results indicate the importance of a previously
unaccounted band structure parameter which, together with a more accurate estimate
of the other tight-binding parameters, results in a significantly improved determination
of the electronic and Landau level structure of TLG.
acknowledgement: This work has been primarily supported by the National Science Foundation
(DMR-1405221) for device fabrication and transport, and partly by ONR Young Investigator
Award N00014-13-1-0610 for data analysis.
author:
- first_name: Leonardo
full_name: Campos, Leonardo C
last_name: Campos
- first_name: Thiti
full_name: Taychatanapat, Thiti
last_name: Taychatanapat
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Kawin
full_name: Surakitbovorn, Kawin N
last_name: Surakitbovorn
- first_name: Kenji
full_name: Watanabe, Kenji
last_name: Watanabe
- first_name: Takashi
full_name: Taniguchi, Takashi
last_name: Taniguchi
- first_name: Dmitry
full_name: Abanin, Dmitry A
last_name: Abanin
- first_name: Pablo
full_name: Jarillo-Herrero, Pablo
last_name: Jarillo Herrero
citation:
ama: Campos L, Taychatanapat T, Serbyn M, et al. Landau Level Splittings, Phase
Transitions, and Nonuniform Charge Distribution in Trilayer Graphene. Physical
Review Letters. 2016;117(6). doi:10.1103/PhysRevLett.117.066601
apa: Campos, L., Taychatanapat, T., Serbyn, M., Surakitbovorn, K., Watanabe, K.,
Taniguchi, T., … Jarillo Herrero, P. (2016). Landau Level Splittings, Phase Transitions,
and Nonuniform Charge Distribution in Trilayer Graphene. Physical Review Letters.
American Physical Society. https://doi.org/10.1103/PhysRevLett.117.066601
chicago: Campos, Leonardo, Thiti Taychatanapat, Maksym Serbyn, Kawin Surakitbovorn,
Kenji Watanabe, Takashi Taniguchi, Dmitry Abanin, and Pablo Jarillo Herrero. “Landau
Level Splittings, Phase Transitions, and Nonuniform Charge Distribution in Trilayer
Graphene.” Physical Review Letters. American Physical Society, 2016. https://doi.org/10.1103/PhysRevLett.117.066601.
ieee: L. Campos et al., “Landau Level Splittings, Phase Transitions, and
Nonuniform Charge Distribution in Trilayer Graphene,” Physical Review Letters,
vol. 117, no. 6. American Physical Society, 2016.
ista: Campos L, Taychatanapat T, Serbyn M, Surakitbovorn K, Watanabe K, Taniguchi
T, Abanin D, Jarillo Herrero P. 2016. Landau Level Splittings, Phase Transitions,
and Nonuniform Charge Distribution in Trilayer Graphene. Physical Review Letters.
117(6).
mla: Campos, Leonardo, et al. “Landau Level Splittings, Phase Transitions, and Nonuniform
Charge Distribution in Trilayer Graphene.” Physical Review Letters, vol.
117, no. 6, American Physical Society, 2016, doi:10.1103/PhysRevLett.117.066601.
short: L. Campos, T. Taychatanapat, M. Serbyn, K. Surakitbovorn, K. Watanabe, T.
Taniguchi, D. Abanin, P. Jarillo Herrero, Physical Review Letters 117 (2016).
date_created: 2018-12-11T11:49:33Z
date_published: 2016-04-01T00:00:00Z
date_updated: 2021-01-12T08:22:26Z
day: '01'
doi: 10.1103/PhysRevLett.117.066601
extern: 1
intvolume: ' 117'
issue: '6'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1607.00784
month: '04'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '6415'
quality_controlled: 0
status: public
title: Landau Level Splittings, Phase Transitions, and Nonuniform Charge Distribution
in Trilayer Graphene
type: journal_article
volume: 117
year: '2016'
...
---
_id: '986'
abstract:
- lang: eng
text: The many-body localization transition (MBLT) between ergodic and many-body
localized phases in disordered interacting systems is a subject of much recent
interest. The statistics of eigenenergies is known to be a powerful probe of crossovers
between ergodic and integrable systems in simpler examples of quantum chaos. We
consider the evolution of the spectral statistics across the MBLT, starting with
mapping to a Brownian motion process that analytically relates the spectral properties
to the statistics of matrix elements. We demonstrate that the flow from Wigner-Dyson
to Poisson statistics is a two-stage process. First, a fractal enhancement of
matrix elements upon approaching the MBLT from the delocalized side produces an
effective power-law interaction between energy levels, and leads to a plasma model
for level statistics. At the second stage, the gas of eigenvalues has local interactions
and the level statistics belongs to a semi-Poisson universality class. We verify
our findings numerically on the XXZ spin chain. We provide a microscopic understanding
of the level statistics across the MBLT and discuss implications for the transition
that are strong constraints on possible theories.
author:
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Joel
full_name: Moore, Joel E
last_name: Moore
citation:
ama: Serbyn M, Moore J. Spectral statistics across the many-body localization transition.
Physical Review B - Condensed Matter and Materials Physics. 2016;93(4).
doi:10.1103/PhysRevB.93.041424
apa: Serbyn, M., & Moore, J. (2016). Spectral statistics across the many-body
localization transition. Physical Review B - Condensed Matter and Materials
Physics. American Physical Society. https://doi.org/10.1103/PhysRevB.93.041424
chicago: Serbyn, Maksym, and Joel Moore. “Spectral Statistics across the Many-Body
Localization Transition.” Physical Review B - Condensed Matter and Materials
Physics. American Physical Society, 2016. https://doi.org/10.1103/PhysRevB.93.041424.
ieee: M. Serbyn and J. Moore, “Spectral statistics across the many-body localization
transition,” Physical Review B - Condensed Matter and Materials Physics,
vol. 93, no. 4. American Physical Society, 2016.
ista: Serbyn M, Moore J. 2016. Spectral statistics across the many-body localization
transition. Physical Review B - Condensed Matter and Materials Physics. 93(4).
mla: Serbyn, Maksym, and Joel Moore. “Spectral Statistics across the Many-Body Localization
Transition.” Physical Review B - Condensed Matter and Materials Physics,
vol. 93, no. 4, American Physical Society, 2016, doi:10.1103/PhysRevB.93.041424.
short: M. Serbyn, J. Moore, Physical Review B - Condensed Matter and Materials Physics
93 (2016).
date_created: 2018-12-11T11:49:33Z
date_published: 2016-01-29T00:00:00Z
date_updated: 2021-01-12T08:22:26Z
day: '29'
doi: 10.1103/PhysRevB.93.041424
extern: 1
intvolume: ' 93'
issue: '4'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1508.07293
month: '01'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '6416'
quality_controlled: 0
status: public
title: Spectral statistics across the many-body localization transition
type: journal_article
volume: 93
year: '2016'
...
---
_id: '9864'
abstract:
- lang: eng
text: Viral capsids are structurally constrained by interactions among the amino
acids (AAs) of their constituent proteins. Therefore, epistasis is expected to
evolve among physically interacting sites and to influence the rates of substitution.
To study the evolution of epistasis, we focused on the major structural protein
of the ϕX174 phage family by, first, reconstructing the ancestral protein sequences
of 18 species using a Bayesian statistical framework. The inferred ancestral reconstruction
differed at eight AAs, for a total of 256 possible ancestral haplotypes. For each
ancestral haplotype and the extant species, we estimated, in silico, the distribution
of free energies and epistasis of the capsid structure. We found that free energy
has not significantly increased but epistasis has. We decomposed epistasis up
to fifth order and found that higher-order epistasis sometimes compensates pairwise
interactions making the free energy seem additive. The dN/dS ratio is low, suggesting
strong purifying selection, and that structure is under stabilizing selection.
We synthesized phages carrying ancestral haplotypes of the coat protein gene and
measured their fitness experimentally. Our findings indicate that stabilizing
mutations can have higher fitness, and that fitness optima do not necessarily
coincide with energy minima.
article_processing_charge: No
author:
- first_name: Rodrigo A
full_name: Fernandes Redondo, Rodrigo A
id: 409D5C96-F248-11E8-B48F-1D18A9856A87
last_name: Fernandes Redondo
orcid: 0000-0002-5837-2793
- first_name: Harold
full_name: de Vladar, Harold
id: 2A181218-F248-11E8-B48F-1D18A9856A87
last_name: de Vladar
orcid: 0000-0002-5985-7653
- first_name: Tomasz
full_name: Włodarski, Tomasz
last_name: Włodarski
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
citation:
ama: Fernandes Redondo RA, de Vladar H, Włodarski T, Bollback JP. Data from evolutionary
interplay between structure, energy and epistasis in the coat protein of the ϕX174
phage family. 2016. doi:10.6084/m9.figshare.4315652.v1
apa: Fernandes Redondo, R. A., de Vladar, H., Włodarski, T., & Bollback, J.
P. (2016). Data from evolutionary interplay between structure, energy and epistasis
in the coat protein of the ϕX174 phage family. The Royal Society. https://doi.org/10.6084/m9.figshare.4315652.v1
chicago: Fernandes Redondo, Rodrigo A, Harold de Vladar, Tomasz Włodarski, and Jonathan
P Bollback. “Data from Evolutionary Interplay between Structure, Energy and Epistasis
in the Coat Protein of the ΦX174 Phage Family.” The Royal Society, 2016. https://doi.org/10.6084/m9.figshare.4315652.v1.
ieee: R. A. Fernandes Redondo, H. de Vladar, T. Włodarski, and J. P. Bollback, “Data
from evolutionary interplay between structure, energy and epistasis in the coat
protein of the ϕX174 phage family.” The Royal Society, 2016.
ista: Fernandes Redondo RA, de Vladar H, Włodarski T, Bollback JP. 2016. Data from
evolutionary interplay between structure, energy and epistasis in the coat protein
of the ϕX174 phage family, The Royal Society, 10.6084/m9.figshare.4315652.v1.
mla: Fernandes Redondo, Rodrigo A., et al. Data from Evolutionary Interplay between
Structure, Energy and Epistasis in the Coat Protein of the ΦX174 Phage Family.
The Royal Society, 2016, doi:10.6084/m9.figshare.4315652.v1.
short: R.A. Fernandes Redondo, H. de Vladar, T. Włodarski, J.P. Bollback, (2016).
date_created: 2021-08-10T08:29:47Z
date_published: 2016-12-14T00:00:00Z
date_updated: 2025-05-28T11:57:06Z
day: '14'
department:
- _id: NiBa
- _id: JoBo
doi: 10.6084/m9.figshare.4315652.v1
main_file_link:
- open_access: '1'
url: https://doi.org/10.6084/m9.figshare.4315652.v1
month: '12'
oa: 1
oa_version: Published Version
publisher: The Royal Society
related_material:
record:
- id: '1077'
relation: used_in_publication
status: public
status: public
title: Data from evolutionary interplay between structure, energy and epistasis in
the coat protein of the ϕX174 phage family
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2016'
...
---
_id: '987'
abstract:
- lang: eng
text: In contrast to bulk FeSe, which exhibits nematic order and low temperature
superconductivity, highly doped FeSe reverses the situation, having high temperature
superconductivity appearing alongside a suppression of nematic order. To investigate
this phenomenon, we study a minimal electronic model of FeSe, with interactions
that enhance nematic fluctuations. This model is sign problem free, and is simulated
using determinant quantum Monte Carlo (DQMC). We developed a DQMC algorithm with
parallel tempering, which proves to be an efficient source of global updates and
allows us to access the region of strong interactions. Over a wide range of intermediate
couplings, we observe superconductivity with an extended s-wave order parameter,
along with enhanced, but short-ranged, q=(0,0) ferro-orbital (nematic) order.
These results are consistent with approximate weak-coupling treatments that predict
that nematic fluctuations lead to superconducting pairing. Surprisingly, in the
parameter range under study, we do not observe nematic long-range order. Instead,
at stronger coupling an unusual insulating phase with q=(π,π) antiferro-orbital
order appears, which is missed by weak-coupling approximations.
acknowledgement: We thank S. Gazit for numerous discussions. This research was supported
by the Gordon and Betty Moore Foundation EPiQS Initiative through Grant No. GBMF4307
(M.S.), the U.S. Department of Energy, Office of Science, Office of Basic Energy
Sciences under Grant No. DE-SC0014671 (R.T.S.), and a Simons Investigator grant
(A.V.).
author:
- first_name: Philipp
full_name: Dumitrescu, Philipp T
last_name: Dumitrescu
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Richard
full_name: Scalettar, Richard T
last_name: Scalettar
- first_name: Ashvin
full_name: Vishwanath, Ashvin K
last_name: Vishwanath
citation:
ama: 'Dumitrescu P, Serbyn M, Scalettar R, Vishwanath A. Superconductivity and nematic
fluctuations in a model of doped FeSe monolayers: Determinant quantum Monte Carlo
study. Physical Review B - Condensed Matter and Materials Physics. 2016;94(15).
doi:10.1103/PhysRevB.94.155127'
apa: 'Dumitrescu, P., Serbyn, M., Scalettar, R., & Vishwanath, A. (2016). Superconductivity
and nematic fluctuations in a model of doped FeSe monolayers: Determinant quantum
Monte Carlo study. Physical Review B - Condensed Matter and Materials Physics.
American Physical Society. https://doi.org/10.1103/PhysRevB.94.155127'
chicago: 'Dumitrescu, Philipp, Maksym Serbyn, Richard Scalettar, and Ashvin Vishwanath.
“Superconductivity and Nematic Fluctuations in a Model of Doped FeSe Monolayers:
Determinant Quantum Monte Carlo Study.” Physical Review B - Condensed Matter
and Materials Physics. American Physical Society, 2016. https://doi.org/10.1103/PhysRevB.94.155127.'
ieee: 'P. Dumitrescu, M. Serbyn, R. Scalettar, and A. Vishwanath, “Superconductivity
and nematic fluctuations in a model of doped FeSe monolayers: Determinant quantum
Monte Carlo study,” Physical Review B - Condensed Matter and Materials Physics,
vol. 94, no. 15. American Physical Society, 2016.'
ista: 'Dumitrescu P, Serbyn M, Scalettar R, Vishwanath A. 2016. Superconductivity
and nematic fluctuations in a model of doped FeSe monolayers: Determinant quantum
Monte Carlo study. Physical Review B - Condensed Matter and Materials Physics.
94(15).'
mla: 'Dumitrescu, Philipp, et al. “Superconductivity and Nematic Fluctuations in
a Model of Doped FeSe Monolayers: Determinant Quantum Monte Carlo Study.” Physical
Review B - Condensed Matter and Materials Physics, vol. 94, no. 15, American
Physical Society, 2016, doi:10.1103/PhysRevB.94.155127.'
short: P. Dumitrescu, M. Serbyn, R. Scalettar, A. Vishwanath, Physical Review B
- Condensed Matter and Materials Physics 94 (2016).
date_created: 2018-12-11T11:49:33Z
date_published: 2016-10-17T00:00:00Z
date_updated: 2021-01-12T08:22:27Z
day: '17'
doi: 10.1103/PhysRevB.94.155127
extern: 1
intvolume: ' 94'
issue: '15'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1512.08523
month: '10'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '6413'
quality_controlled: 0
status: public
title: 'Superconductivity and nematic fluctuations in a model of doped FeSe monolayers:
Determinant quantum Monte Carlo study'
type: journal_article
volume: 94
year: '2016'
...
---
_id: '366'
abstract:
- lang: eng
text: Cesium lead halide (CsPbX3, X = Cl, Br, I) nanocrystals (NCs) offer exceptional
optical properties for several potential applications but their implementation
is hindered by a low chemical and structural stability and limited processability.
In the present work, we developed a new method to efficiently coat CsPbX3 NCs,
which resulted in their increased chemical and optical stability as well as processability.
The method is based on the incorporation of poly(maleic anhydride-alt-1-octadecene)
(PMA) into the synthesis of the perovskite NCs. The presence of PMA in the ligand
shell stabilizes the NCs by tightening the ligand binding, limiting in this way
the NC surface interaction with the surrounding media. We further show that these
NCs can be embedded in self-standing silicone/glass plates as down-conversion
filters for the fabrication of monochromatic green and white light emitting diodes
(LEDs) with narrow bandwidths and appealing color characteristics.
acknowledgement: This work was supported by the European Regional Development Funds,
the Framework 7 program under project UNION (FP7-NMP-2012-310250) and HI-LED (FP7-ICT-2013-11-
619912), as well as the Spanish MINECO Projects BOOSTER (ENE2013-46624-C4-3-R) and
AMALIE (TEC2012-38901- C02-01). M.M. thanks the Spanish MINECO for financial support
through the Juan de la Cierva-formacion program. A.G. and J.A. acknowledge funding
from Generalitat de Catalunya 2014 SGR 1638 and the Spanish MINECO MAT2014-51480-
ERC (e-ATOM) and Severo Ochoa Excellence Program. We would like to thank Pablo Guardia
for fruitful discussions.
author:
- first_name: Michaela
full_name: Meyn, Michaela
last_name: Meyn
- first_name: Mariano
full_name: Perálvarez, Mariano
last_name: Perálvarez
- first_name: Amelie
full_name: Heuer Jungemann, Amelie
last_name: Heuer Jungemann
- first_name: Wim
full_name: Hertog, Wim
last_name: Hertog
- first_name: Maria
full_name: Ibanez Sabate, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibanez Sabate
orcid: 0000-0001-5013-2843
- first_name: Raquel
full_name: Nafria, Raquel
last_name: Nafria
- first_name: Aziz
full_name: Genç, Aziz
last_name: Genç
- first_name: Jordi
full_name: Arbiol, Jordi
last_name: Arbiol
- first_name: Maksym
full_name: Kovalenko, Maksym
last_name: Kovalenko
- first_name: Josep
full_name: Carreras, Josep
last_name: Carreras
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
- first_name: Antonios
full_name: Kanaras, Antonios
last_name: Kanaras
citation:
ama: Meyn M, Perálvarez M, Heuer Jungemann A, et al. Polymer enhanced stability
of inorganic perovskite nanocrystals and their application in color conversion
LEDs. ACS Applied Materials and Interfaces. 2016;8(30):19579-19586. doi:10.1021/acsami.6b02529
apa: Meyn, M., Perálvarez, M., Heuer Jungemann, A., Hertog, W., Ibáñez, M., Nafria,
R., … Kanaras, A. (2016). Polymer enhanced stability of inorganic perovskite nanocrystals
and their application in color conversion LEDs. ACS Applied Materials and Interfaces.
American Chemical Society. https://doi.org/10.1021/acsami.6b02529
chicago: Meyn, Michaela, Mariano Perálvarez, Amelie Heuer Jungemann, Wim Hertog,
Maria Ibáñez, Raquel Nafria, Aziz Genç, et al. “Polymer Enhanced Stability of
Inorganic Perovskite Nanocrystals and Their Application in Color Conversion LEDs.”
ACS Applied Materials and Interfaces. American Chemical Society, 2016.
https://doi.org/10.1021/acsami.6b02529.
ieee: M. Meyn et al., “Polymer enhanced stability of inorganic perovskite
nanocrystals and their application in color conversion LEDs,” ACS Applied Materials
and Interfaces, vol. 8, no. 30. American Chemical Society, pp. 19579–19586,
2016.
ista: Meyn M, Perálvarez M, Heuer Jungemann A, Hertog W, Ibáñez M, Nafria R, Genç
A, Arbiol J, Kovalenko M, Carreras J, Cabot A, Kanaras A. 2016. Polymer enhanced
stability of inorganic perovskite nanocrystals and their application in color
conversion LEDs. ACS Applied Materials and Interfaces. 8(30), 19579–19586.
mla: Meyn, Michaela, et al. “Polymer Enhanced Stability of Inorganic Perovskite
Nanocrystals and Their Application in Color Conversion LEDs.” ACS Applied Materials
and Interfaces, vol. 8, no. 30, American Chemical Society, 2016, pp. 19579–86,
doi:10.1021/acsami.6b02529.
short: M. Meyn, M. Perálvarez, A. Heuer Jungemann, W. Hertog, M. Ibáñez, R. Nafria,
A. Genç, J. Arbiol, M. Kovalenko, J. Carreras, A. Cabot, A. Kanaras, ACS Applied
Materials and Interfaces 8 (2016) 19579–19586.
date_created: 2018-12-11T11:46:03Z
date_published: 2016-07-25T00:00:00Z
date_updated: 2021-01-12T07:44:58Z
day: '25'
doi: 10.1021/acsami.6b02529
extern: '1'
intvolume: ' 8'
issue: '30'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprints.soton.ac.uk/398581/
month: '07'
oa: 1
oa_version: None
page: 19579 - 19586
publication: ACS Applied Materials and Interfaces
publication_status: published
publisher: American Chemical Society
publist_id: '7460'
status: public
title: Polymer enhanced stability of inorganic perovskite nanocrystals and their application
in color conversion LEDs
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2016'
...
---
_id: '389'
abstract:
- lang: eng
text: The coherent optical manipulation of solids is emerging as a promising way
to engineer novel quantum states of matter. The strong time-periodic potential
of intense laser light can be used to generate hybrid photon-electron states.
Interaction of light with Bloch states leads to Floquet-Bloch states, which are
essential in realizing new photo-induced quantum phases. Similarly, dressing of
free-electron states near the surface of a solid generates Volkov states, which
are used to study nonlinear optics in atoms and semiconductors. The interaction
of these two dynamic states with each other remains an open experimental problem.
Here we use time- and angle-resolved photoemission spectroscopy (Tr-ARPES) to
selectively study the transition between these two states on the surface of the
topological insulator Bi2Se3. We find that the coupling between the two strongly
depends on the electron momentum, providing a route to enhance or inhibit it.
Moreover, by controlling the light polarization we can negate Volkov states to
generate pure Floquet-Bloch states. This work establishes a systematic path for
the coherent manipulation of solids via light-matter interaction.
acknowledgement: The authors would like to thank C. Lee for useful discussions. This
work is supported by US Department of Energy (DOE), Basic Energy Sciences, Division
of Materials Sciences and Engineering (experimental set-up, data acquisition and
theory), Army Research Office (electron spectrometer) and by the Gordon and Betty
Moore Foundation’s EPiQS Initiative through Grant GBMF4540 (data analysis).
author:
- first_name: Fahad
full_name: Mahmood, Fahad
last_name: Mahmood
- first_name: Ching
full_name: Chan, Ching
last_name: Chan
- first_name: Zhanybek
full_name: Alpichshev, Zhanybek
id: 45E67A2A-F248-11E8-B48F-1D18A9856A87
last_name: Alpichshev
orcid: 0000-0002-7183-5203
- first_name: Dillon
full_name: Gardner, Dillon
last_name: Gardner
- first_name: Young
full_name: Lee, Young
last_name: Lee
- first_name: Patrick
full_name: Lee, Patrick
last_name: Lee
- first_name: Nuh
full_name: Gedik, Nuh
last_name: Gedik
citation:
ama: Mahmood F, Chan C, Alpichshev Z, et al. Selective scattering between Floquet
Bloch and Volkov states in a topological insulator. Nature Physics. 2016;12(4):306-310.
doi:10.1038/nphys3609
apa: Mahmood, F., Chan, C., Alpichshev, Z., Gardner, D., Lee, Y., Lee, P., &
Gedik, N. (2016). Selective scattering between Floquet Bloch and Volkov states
in a topological insulator. Nature Physics. Nature Publishing Group. https://doi.org/10.1038/nphys3609
chicago: Mahmood, Fahad, Ching Chan, Zhanybek Alpichshev, Dillon Gardner, Young
Lee, Patrick Lee, and Nuh Gedik. “Selective Scattering between Floquet Bloch and
Volkov States in a Topological Insulator.” Nature Physics. Nature Publishing
Group, 2016. https://doi.org/10.1038/nphys3609.
ieee: F. Mahmood et al., “Selective scattering between Floquet Bloch and
Volkov states in a topological insulator,” Nature Physics, vol. 12, no.
4. Nature Publishing Group, pp. 306–310, 2016.
ista: Mahmood F, Chan C, Alpichshev Z, Gardner D, Lee Y, Lee P, Gedik N. 2016. Selective
scattering between Floquet Bloch and Volkov states in a topological insulator.
Nature Physics. 12(4), 306–310.
mla: Mahmood, Fahad, et al. “Selective Scattering between Floquet Bloch and Volkov
States in a Topological Insulator.” Nature Physics, vol. 12, no. 4, Nature
Publishing Group, 2016, pp. 306–10, doi:10.1038/nphys3609.
short: F. Mahmood, C. Chan, Z. Alpichshev, D. Gardner, Y. Lee, P. Lee, N. Gedik,
Nature Physics 12 (2016) 306–310.
date_created: 2018-12-11T11:46:11Z
date_published: 2016-04-01T00:00:00Z
date_updated: 2021-01-12T07:52:59Z
day: '01'
doi: 10.1038/nphys3609
extern: '1'
intvolume: ' 12'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1512.05714
month: '04'
oa: 1
oa_version: None
page: 306 - 310
publication: Nature Physics
publication_status: published
publisher: Nature Publishing Group
publist_id: '7440'
status: public
title: Selective scattering between Floquet Bloch and Volkov states in a topological
insulator
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2016'
...
---
_id: '257'
abstract:
- lang: eng
text: For suitable pairs of diagonal quadratic forms in eight variables we use the
circle method to investigate the density of simultaneous integer solutions and
relate this to the problem of estimating linear correlations among sums of two
squares.
acknowledgement: While working on this paper the first author was supported by ERC
grant 306457 and the second author was supported by SwarnaJayanti Fellowship 2011–12,
DST, Government of India.
author:
- first_name: Timothy D
full_name: Timothy Browning
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Ritabrata
full_name: Munshi, Ritabrata
last_name: Munshi
citation:
ama: Browning TD, Munshi R. Pairs of diagonal quadratic forms and linear correlations
among sums of two squares. Forum Mathematicum. 2015;27(4):2025-2050. doi:10.1515/forum-2013-6024
apa: Browning, T. D., & Munshi, R. (2015). Pairs of diagonal quadratic forms
and linear correlations among sums of two squares. Forum Mathematicum.
Walter de Gruyter GmbH. https://doi.org/10.1515/forum-2013-6024
chicago: Browning, Timothy D, and Ritabrata Munshi. “Pairs of Diagonal Quadratic
Forms and Linear Correlations among Sums of Two Squares.” Forum Mathematicum.
Walter de Gruyter GmbH, 2015. https://doi.org/10.1515/forum-2013-6024.
ieee: T. D. Browning and R. Munshi, “Pairs of diagonal quadratic forms and linear
correlations among sums of two squares,” Forum Mathematicum, vol. 27, no.
4. Walter de Gruyter GmbH, pp. 2025–2050, 2015.
ista: Browning TD, Munshi R. 2015. Pairs of diagonal quadratic forms and linear
correlations among sums of two squares. Forum Mathematicum. 27(4), 2025–2050.
mla: Browning, Timothy D., and Ritabrata Munshi. “Pairs of Diagonal Quadratic Forms
and Linear Correlations among Sums of Two Squares.” Forum Mathematicum,
vol. 27, no. 4, Walter de Gruyter GmbH, 2015, pp. 2025–50, doi:10.1515/forum-2013-6024.
short: T.D. Browning, R. Munshi, Forum Mathematicum 27 (2015) 2025–2050.
date_created: 2018-12-11T11:45:28Z
date_published: 2015-07-10T00:00:00Z
date_updated: 2021-01-12T06:58:18Z
day: '10'
doi: 10.1515/forum-2013-6024
extern: 1
intvolume: ' 27'
issue: '4'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1302.2434
month: '07'
oa: 1
page: 2025 - 2050
publication: Forum Mathematicum
publication_status: published
publisher: Walter de Gruyter GmbH
publist_id: '7645'
quality_controlled: 0
status: public
title: Pairs of diagonal quadratic forms and linear correlations among sums of two
squares
type: journal_article
volume: 27
year: '2015'
...
---
_id: '271'
abstract:
- lang: eng
text: We show that a non-singular integral form of degree d is soluble non-trivially
over the integers if and only if it is soluble non-trivially over the reals and
the p-adic numbers, provided that the form has at least (d-\sqrt{d}/2)2^d variables.
This improves on a longstanding result of Birch.
acknowledgement: While working on this paper the authors were supported by the Leverhulme
Trust and ERC grant 306457.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Sean
full_name: Prendiville, Sean
last_name: Prendiville
citation:
ama: Browning TD, Prendiville S. Improvements in Birch’s theorem on forms in many
variables. Journal fur die Reine und Angewandte Mathematik. 2017(731):203-234.
doi:10.1515/crelle-2014-0122
apa: Browning, T. D., & Prendiville, S. (n.d.). Improvements in Birch’s theorem
on forms in many variables. Journal Fur Die Reine Und Angewandte Mathematik.
Walter de Gruyter. https://doi.org/10.1515/crelle-2014-0122
chicago: Browning, Timothy D, and Sean Prendiville. “Improvements in Birch’s Theorem
on Forms in Many Variables.” Journal Fur Die Reine Und Angewandte Mathematik.
Walter de Gruyter, n.d. https://doi.org/10.1515/crelle-2014-0122.
ieee: T. D. Browning and S. Prendiville, “Improvements in Birch’s theorem on forms
in many variables,” Journal fur die Reine und Angewandte Mathematik, vol.
2017, no. 731. Walter de Gruyter, pp. 203–234.
ista: Browning TD, Prendiville S. Improvements in Birch’s theorem on forms in many
variables. Journal fur die Reine und Angewandte Mathematik. 2017(731), 203–234.
mla: Browning, Timothy D., and Sean Prendiville. “Improvements in Birch’s Theorem
on Forms in Many Variables.” Journal Fur Die Reine Und Angewandte Mathematik,
vol. 2017, no. 731, Walter de Gruyter, pp. 203–34, doi:10.1515/crelle-2014-0122.
short: T.D. Browning, S. Prendiville, Journal Fur Die Reine Und Angewandte Mathematik
2017 (n.d.) 203–234.
date_created: 2018-12-11T11:45:32Z
date_published: 2015-02-20T00:00:00Z
date_updated: 2024-03-05T12:09:22Z
day: '20'
doi: 10.1515/crelle-2014-0122
extern: '1'
external_id:
arxiv:
- '1402.4489'
intvolume: ' 2017'
issue: '731'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1402.4489
month: '02'
oa: 1
oa_version: Preprint
page: 203 - 234
publication: Journal fur die Reine und Angewandte Mathematik
publication_identifier:
issn:
- 0075-4102
publication_status: submitted
publisher: Walter de Gruyter
publist_id: '7631'
quality_controlled: '1'
related_material:
record:
- id: '256'
relation: later_version
status: public
status: public
title: Improvements in Birch's theorem on forms in many variables
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2017
year: '2015'
...
---
_id: '10748'
abstract:
- lang: eng
text: The study of fluxoid states and fluxoid dynamics in mesoscopic iron-based
superconducting rings is valuable for characterizing the basic properties of the
superconductor, and may also provide important insight into the superconducting
paring symmetry. We report the fabrications of micron-sized rings and disks from
thin films of Fe(Se, Te) grown by molecular beam epitaxy. In order to study fluxoid
states in rings we developed a custom-tailored version of magnetic force microscopy
(MFM). This technique has a number of qualitative advantages for working with
mesoscopic superconducting samples in comparison to the conventional MFM and other
imaging techniques. We observed metastable fluxoid states in rings of different
sizes. Thermally activated fluxoid dynamics of these states was studied and modeled.
In addition, we found different regimes of interaction between Fe(Se, Te) ring
and MFM tip which are explained. Possibilities of the existence of exotic vortex
states and proposals for experiments to test the symmetry of the superconducting
order parameter in iron based superconductors are analyzed.
alternative_title:
- Bulletin of the American Physical Society
article_number: G16.00009
article_processing_charge: No
author:
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: Can
full_name: Zhang, Can
last_name: Zhang
- first_name: Tyler
full_name: Naibert, Tyler
last_name: Naibert
- first_name: James
full_name: Eckstein, James
last_name: Eckstein
- first_name: Raffi
full_name: Budakian, Raffi
last_name: Budakian
citation:
ama: 'Polshyn H, Zhang C, Naibert T, Eckstein J, Budakian R. Study of Fe (Se, Te)
micron-sized rings by magnetic force microscopy. In: APS March Meeting 2015.
Vol 60. American Physical Society; 2015.'
apa: 'Polshyn, H., Zhang, C., Naibert, T., Eckstein, J., & Budakian, R. (2015).
Study of Fe (Se, Te) micron-sized rings by magnetic force microscopy. In APS
March Meeting 2015 (Vol. 60). San Antonio, TX, United States: American Physical
Society.'
chicago: Polshyn, Hryhoriy, Can Zhang, Tyler Naibert, James Eckstein, and Raffi
Budakian. “Study of Fe (Se, Te) Micron-Sized Rings by Magnetic Force Microscopy.”
In APS March Meeting 2015, Vol. 60. American Physical Society, 2015.
ieee: H. Polshyn, C. Zhang, T. Naibert, J. Eckstein, and R. Budakian, “Study of
Fe (Se, Te) micron-sized rings by magnetic force microscopy,” in APS March
Meeting 2015, San Antonio, TX, United States, 2015, vol. 60, no. 1.
ista: 'Polshyn H, Zhang C, Naibert T, Eckstein J, Budakian R. 2015. Study of Fe
(Se, Te) micron-sized rings by magnetic force microscopy. APS March Meeting 2015.
APS: American Physical Society, Bulletin of the American Physical Society, vol.
60, G16.00009.'
mla: Polshyn, Hryhoriy, et al. “Study of Fe (Se, Te) Micron-Sized Rings by Magnetic
Force Microscopy.” APS March Meeting 2015, vol. 60, no. 1, G16.00009, American
Physical Society, 2015.
short: H. Polshyn, C. Zhang, T. Naibert, J. Eckstein, R. Budakian, in:, APS March
Meeting 2015, American Physical Society, 2015.
conference:
end_date: 2015-03-06
location: San Antonio, TX, United States
name: 'APS: American Physical Society'
start_date: 2015-03-02
date_created: 2022-02-08T10:17:09Z
date_published: 2015-03-01T00:00:00Z
date_updated: 2022-02-08T10:42:53Z
day: '01'
extern: '1'
intvolume: ' 60'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://meetings.aps.org/Meeting/MAR15/Event/238442
month: '03'
oa: 1
oa_version: Published Version
publication: APS March Meeting 2015
publication_identifier:
issn:
- 0003-0503
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Study of Fe (Se, Te) micron-sized rings by magnetic force microscopy
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 60
year: '2015'
...
---
_id: '10794'
abstract:
- lang: eng
text: Mathematical models are of fundamental importance in the understanding of
complex population dynamics. For instance, they can be used to predict the population
evolution starting from different initial conditions or to test how a system responds
to external perturbations. For this analysis to be meaningful in real applications,
however, it is of paramount importance to choose an appropriate model structure
and to infer the model parameters from measured data. While many parameter inference
methods are available for models based on deterministic ordinary differential
equations, the same does not hold for more detailed individual-based models. Here
we consider, in particular, stochastic models in which the time evolution of the
species abundances is described by a continuous-time Markov chain. These models
are governed by a master equation that is typically difficult to solve. Consequently,
traditional inference methods that rely on iterative evaluation of parameter likelihoods
are computationally intractable. The aim of this paper is to present recent advances
in parameter inference for continuous-time Markov chain models, based on a moment
closure approximation of the parameter likelihood, and to investigate how these
results can help in understanding, and ultimately controlling, complex systems
in ecology. Specifically, we illustrate through an agricultural pest case study
how parameters of a stochastic individual-based model can be identified from measured
data and how the resulting model can be used to solve an optimal control problem
in a stochastic setting. In particular, we show how the matter of determining
the optimal combination of two different pest control methods can be formulated
as a chance constrained optimization problem where the control action is modeled
as a state reset, leading to a hybrid system formulation.
acknowledgement: "The authors would like to acknowledge contributions from Baptiste
Mottet who performed preliminary analysis regarding parameter inference for the
considered case study in a student project (Mottet, 2014/2015).\r\nThe research
leading to these results has received funding from the People Programme (Marie Curie
Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under
REA grant agreement No. [291734] and from SystemsX under the project SignalX."
article_number: '42'
article_processing_charge: No
article_type: original
author:
- first_name: Francesca
full_name: Parise, Francesca
last_name: Parise
- first_name: John
full_name: Lygeros, John
last_name: Lygeros
- first_name: Jakob
full_name: Ruess, Jakob
id: 4A245D00-F248-11E8-B48F-1D18A9856A87
last_name: Ruess
orcid: 0000-0003-1615-3282
citation:
ama: 'Parise F, Lygeros J, Ruess J. Bayesian inference for stochastic individual-based
models of ecological systems: a pest control simulation study. Frontiers in
Environmental Science. 2015;3. doi:10.3389/fenvs.2015.00042'
apa: 'Parise, F., Lygeros, J., & Ruess, J. (2015). Bayesian inference for stochastic
individual-based models of ecological systems: a pest control simulation study.
Frontiers in Environmental Science. Frontiers. https://doi.org/10.3389/fenvs.2015.00042'
chicago: 'Parise, Francesca, John Lygeros, and Jakob Ruess. “Bayesian Inference
for Stochastic Individual-Based Models of Ecological Systems: A Pest Control Simulation
Study.” Frontiers in Environmental Science. Frontiers, 2015. https://doi.org/10.3389/fenvs.2015.00042.'
ieee: 'F. Parise, J. Lygeros, and J. Ruess, “Bayesian inference for stochastic individual-based
models of ecological systems: a pest control simulation study,” Frontiers in
Environmental Science, vol. 3. Frontiers, 2015.'
ista: 'Parise F, Lygeros J, Ruess J. 2015. Bayesian inference for stochastic individual-based
models of ecological systems: a pest control simulation study. Frontiers in Environmental
Science. 3, 42.'
mla: 'Parise, Francesca, et al. “Bayesian Inference for Stochastic Individual-Based
Models of Ecological Systems: A Pest Control Simulation Study.” Frontiers in
Environmental Science, vol. 3, 42, Frontiers, 2015, doi:10.3389/fenvs.2015.00042.'
short: F. Parise, J. Lygeros, J. Ruess, Frontiers in Environmental Science 3 (2015).
date_created: 2022-02-25T11:42:25Z
date_published: 2015-06-10T00:00:00Z
date_updated: 2022-02-25T11:59:23Z
day: '10'
ddc:
- '000'
- '570'
department:
- _id: ToHe
- _id: GaTk
doi: 10.3389/fenvs.2015.00042
ec_funded: 1
file:
- access_level: open_access
checksum: 26c222487564e1be02a11d688d6f769d
content_type: application/pdf
creator: dernst
date_created: 2022-02-25T11:55:26Z
date_updated: 2022-02-25T11:55:26Z
file_id: '10795'
file_name: 2015_FrontiersEnvironmScience_Parise.pdf
file_size: 1371201
relation: main_file
success: 1
file_date_updated: 2022-02-25T11:55:26Z
has_accepted_license: '1'
intvolume: ' 3'
keyword:
- General Environmental Science
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Frontiers in Environmental Science
publication_identifier:
issn:
- 2296-665X
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Bayesian inference for stochastic individual-based models of ecological systems:
a pest control simulation study'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2015'
...
---
_id: '11073'
abstract:
- lang: eng
text: Human cancer cells bear complex chromosome rearrangements that can be potential
drivers of cancer development. However, the molecular mechanisms underlying these
rearrangements have been unclear. Zhang et al. use a new technique combining live-cell
imaging and single-cell sequencing to demonstrate that chromosomes mis-segregated
to micronuclei frequently undergo chromothripsis-like rearrangements in the subsequent
cell cycle.
article_processing_charge: No
article_type: original
author:
- first_name: Emily M.
full_name: Hatch, Emily M.
last_name: Hatch
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Hatch EM, Hetzer M. Linking micronuclei to chromosome fragmentation. Cell.
2015;161(7):1502-1504. doi:10.1016/j.cell.2015.06.005
apa: Hatch, E. M., & Hetzer, M. (2015). Linking micronuclei to chromosome fragmentation.
Cell. Elsevier. https://doi.org/10.1016/j.cell.2015.06.005
chicago: Hatch, Emily M., and Martin Hetzer. “Linking Micronuclei to Chromosome
Fragmentation.” Cell. Elsevier, 2015. https://doi.org/10.1016/j.cell.2015.06.005.
ieee: E. M. Hatch and M. Hetzer, “Linking micronuclei to chromosome fragmentation,”
Cell, vol. 161, no. 7. Elsevier, pp. 1502–1504, 2015.
ista: Hatch EM, Hetzer M. 2015. Linking micronuclei to chromosome fragmentation.
Cell. 161(7), 1502–1504.
mla: Hatch, Emily M., and Martin Hetzer. “Linking Micronuclei to Chromosome Fragmentation.”
Cell, vol. 161, no. 7, Elsevier, 2015, pp. 1502–04, doi:10.1016/j.cell.2015.06.005.
short: E.M. Hatch, M. Hetzer, Cell 161 (2015) 1502–1504.
date_created: 2022-04-07T07:48:49Z
date_published: 2015-06-18T00:00:00Z
date_updated: 2022-07-18T08:34:33Z
day: '18'
doi: 10.1016/j.cell.2015.06.005
extern: '1'
external_id:
pmid:
- '26091034'
intvolume: ' 161'
issue: '7'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cell.2015.06.005
month: '06'
oa: 1
oa_version: Published Version
page: 1502-1504
pmid: 1
publication: Cell
publication_identifier:
issn:
- 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Linking micronuclei to chromosome fragmentation
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 161
year: '2015'
...
---
_id: '11074'
article_processing_charge: No
article_type: original
author:
- first_name: Emily M.
full_name: Hatch, Emily M.
last_name: Hatch
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Hatch EM, Hetzer M. Chromothripsis. Current Biology. 2015;25(10):PR397-R399.
doi:10.1016/j.cub.2015.02.033
apa: Hatch, E. M., & Hetzer, M. (2015). Chromothripsis. Current Biology.
Elsevier. https://doi.org/10.1016/j.cub.2015.02.033
chicago: Hatch, Emily M., and Martin Hetzer. “Chromothripsis.” Current Biology.
Elsevier, 2015. https://doi.org/10.1016/j.cub.2015.02.033.
ieee: E. M. Hatch and M. Hetzer, “Chromothripsis,” Current Biology, vol.
25, no. 10. Elsevier, pp. PR397-R399, 2015.
ista: Hatch EM, Hetzer M. 2015. Chromothripsis. Current Biology. 25(10), PR397-R399.
mla: Hatch, Emily M., and Martin Hetzer. “Chromothripsis.” Current Biology,
vol. 25, no. 10, Elsevier, 2015, pp. PR397-R399, doi:10.1016/j.cub.2015.02.033.
short: E.M. Hatch, M. Hetzer, Current Biology 25 (2015) PR397-R399.
date_created: 2022-04-07T07:49:00Z
date_published: 2015-05-18T00:00:00Z
date_updated: 2022-07-18T08:34:34Z
day: '18'
doi: 10.1016/j.cub.2015.02.033
extern: '1'
external_id:
pmid:
- '25989073'
intvolume: ' 25'
issue: '10'
keyword:
- General Agricultural and Biological Sciences
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cub.2015.02.033
month: '05'
oa: 1
oa_version: Published Version
page: PR397-R399
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chromothripsis
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 25
year: '2015'
...
---
_id: '11076'
abstract:
- lang: eng
text: Nuclear pore complexes (NPCs) are composed of several copies of ∼30 different
proteins called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE)
and regulate the nucleocytoplasmic trafficking of macromolecules. Beyond this
vital role, NPC components influence genome functions in a transport-independent
manner. Nups play an evolutionarily conserved role in gene expression regulation
that, in metazoans, extends into the nuclear interior. Additionally, in proliferative
cells, Nups play a crucial role in genome integrity maintenance and mitotic progression.
Here we discuss genome-related functions of Nups and their impact on essential
DNA metabolism processes such as transcription, chromosome duplication, and segregation.
article_processing_charge: No
article_type: original
author:
- first_name: Arkaitz
full_name: Ibarra, Arkaitz
last_name: Ibarra
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Ibarra A, Hetzer M. Nuclear pore proteins and the control of genome functions.
Genes & Development. 2015;29(4):337-349. doi:10.1101/gad.256495.114
apa: Ibarra, A., & Hetzer, M. (2015). Nuclear pore proteins and the control
of genome functions. Genes & Development. Cold Spring Harbor Laboratory.
https://doi.org/10.1101/gad.256495.114
chicago: Ibarra, Arkaitz, and Martin Hetzer. “Nuclear Pore Proteins and the Control
of Genome Functions.” Genes & Development. Cold Spring Harbor Laboratory,
2015. https://doi.org/10.1101/gad.256495.114.
ieee: A. Ibarra and M. Hetzer, “Nuclear pore proteins and the control of genome
functions,” Genes & Development, vol. 29, no. 4. Cold Spring Harbor
Laboratory, pp. 337–349, 2015.
ista: Ibarra A, Hetzer M. 2015. Nuclear pore proteins and the control of genome
functions. Genes & Development. 29(4), 337–349.
mla: Ibarra, Arkaitz, and Martin Hetzer. “Nuclear Pore Proteins and the Control
of Genome Functions.” Genes & Development, vol. 29, no. 4, Cold Spring
Harbor Laboratory, 2015, pp. 337–49, doi:10.1101/gad.256495.114.
short: A. Ibarra, M. Hetzer, Genes & Development 29 (2015) 337–349.
date_created: 2022-04-07T07:49:21Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2022-07-18T08:43:20Z
day: '01'
doi: 10.1101/gad.256495.114
extern: '1'
external_id:
pmid:
- '25691464'
intvolume: ' 29'
issue: '4'
keyword:
- Developmental Biology
- Genetics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/gad.256495.114
month: '02'
oa: 1
oa_version: Published Version
page: 337-349
pmid: 1
publication: Genes & Development
publication_identifier:
eissn:
- 1549-5477
issn:
- 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nuclear pore proteins and the control of genome functions
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 29
year: '2015'
...
---
_id: '11077'
abstract:
- lang: eng
text: Nucleoporins (Nups) are a family of proteins best known as the constituent
building blocks of nuclear pore complexes (NPCs), membrane-embedded channels that
mediate nuclear transport across the nuclear envelope. Recent evidence suggests
that several Nups have additional roles in controlling the activation and silencing
of developmental genes; however, the mechanistic details of these functions remain
poorly understood. Here, we show that depletion of Nup153 in mouse embryonic stem
cells (mESCs) causes the derepression of developmental genes and induction of
early differentiation. This loss of stem cell identity is not associated with
defects in the nuclear import of key pluripotency factors. Rather, Nup153 binds
around the transcriptional start site (TSS) of developmental genes and mediates
the recruitment of the polycomb-repressive complex 1 (PRC1) to a subset of its
target loci. Our results demonstrate a chromatin-associated role of Nup153 in
maintaining stem cell pluripotency by functioning in mammalian epigenetic gene
silencing.
article_processing_charge: No
article_type: original
author:
- first_name: Filipe V.
full_name: Jacinto, Filipe V.
last_name: Jacinto
- first_name: Chris
full_name: Benner, Chris
last_name: Benner
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Jacinto FV, Benner C, Hetzer M. The nucleoporin Nup153 regulates embryonic
stem cell pluripotency through gene silencing. Genes & Development.
2015;29(12):1224-1238. doi:10.1101/gad.260919.115
apa: Jacinto, F. V., Benner, C., & Hetzer, M. (2015). The nucleoporin Nup153
regulates embryonic stem cell pluripotency through gene silencing. Genes &
Development. Cold Spring Harbor Laboratory. https://doi.org/10.1101/gad.260919.115
chicago: Jacinto, Filipe V., Chris Benner, and Martin Hetzer. “The Nucleoporin Nup153
Regulates Embryonic Stem Cell Pluripotency through Gene Silencing.” Genes &
Development. Cold Spring Harbor Laboratory, 2015. https://doi.org/10.1101/gad.260919.115.
ieee: F. V. Jacinto, C. Benner, and M. Hetzer, “The nucleoporin Nup153 regulates
embryonic stem cell pluripotency through gene silencing,” Genes & Development,
vol. 29, no. 12. Cold Spring Harbor Laboratory, pp. 1224–1238, 2015.
ista: Jacinto FV, Benner C, Hetzer M. 2015. The nucleoporin Nup153 regulates embryonic
stem cell pluripotency through gene silencing. Genes & Development. 29(12),
1224–1238.
mla: Jacinto, Filipe V., et al. “The Nucleoporin Nup153 Regulates Embryonic Stem
Cell Pluripotency through Gene Silencing.” Genes & Development, vol.
29, no. 12, Cold Spring Harbor Laboratory, 2015, pp. 1224–38, doi:10.1101/gad.260919.115.
short: F.V. Jacinto, C. Benner, M. Hetzer, Genes & Development 29 (2015) 1224–1238.
date_created: 2022-04-07T07:49:31Z
date_published: 2015-06-16T00:00:00Z
date_updated: 2022-07-18T08:43:51Z
day: '16'
doi: 10.1101/gad.260919.115
extern: '1'
external_id:
pmid:
- '26080816'
intvolume: ' 29'
issue: '12'
keyword:
- Developmental Biology
- Genetics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/gad.260919.115
month: '06'
oa: 1
oa_version: Published Version
page: 1224-1238
pmid: 1
publication: Genes & Development
publication_identifier:
eissn:
- 1549-5477
issn:
- 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory
quality_controlled: '1'
scopus_import: '1'
status: public
title: The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene
silencing
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 29
year: '2015'
...
---
_id: '11078'
abstract:
- lang: eng
text: Aging is associated with the decline of protein, cell, and organ function.
Here, we use an integrated approach to characterize gene expression, bulk translation,
and cell biology in the brains and livers of young and old rats. We identify 468
differences in protein abundance between young and old animals. The majority are
a consequence of altered translation output, that is, the combined effect of changes
in transcript abundance and translation efficiency. In addition, we identify 130
proteins whose overall abundance remains unchanged but whose sub-cellular localization,
phosphorylation state, or splice-form varies. While some protein-level differences
appear to be a generic property of the rats’ chronological age, the majority are
specific to one organ. These may be a consequence of the organ’s physiology or
the chronological age of the cells within the tissue. Taken together, our study
provides an initial view of the proteome at the molecular, sub-cellular, and organ
level in young and old rats.
article_processing_charge: No
article_type: original
author:
- first_name: Alessandro
full_name: Ori, Alessandro
last_name: Ori
- first_name: Brandon H.
full_name: Toyama, Brandon H.
last_name: Toyama
- first_name: Michael S.
full_name: Harris, Michael S.
last_name: Harris
- first_name: Thomas
full_name: Bock, Thomas
last_name: Bock
- first_name: Murat
full_name: Iskar, Murat
last_name: Iskar
- first_name: Peer
full_name: Bork, Peer
last_name: Bork
- first_name: Nicholas T.
full_name: Ingolia, Nicholas T.
last_name: Ingolia
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
- first_name: Martin
full_name: Beck, Martin
last_name: Beck
citation:
ama: Ori A, Toyama BH, Harris MS, et al. Integrated transcriptome and proteome analyses
reveal organ-specific proteome deterioration in old rats. Cell Systems.
2015;1(3):P224-237. doi:10.1016/j.cels.2015.08.012
apa: Ori, A., Toyama, B. H., Harris, M. S., Bock, T., Iskar, M., Bork, P., … Beck,
M. (2015). Integrated transcriptome and proteome analyses reveal organ-specific
proteome deterioration in old rats. Cell Systems. Elsevier. https://doi.org/10.1016/j.cels.2015.08.012
chicago: Ori, Alessandro, Brandon H. Toyama, Michael S. Harris, Thomas Bock, Murat
Iskar, Peer Bork, Nicholas T. Ingolia, Martin Hetzer, and Martin Beck. “Integrated
Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration
in Old Rats.” Cell Systems. Elsevier, 2015. https://doi.org/10.1016/j.cels.2015.08.012.
ieee: A. Ori et al., “Integrated transcriptome and proteome analyses reveal
organ-specific proteome deterioration in old rats,” Cell Systems, vol.
1, no. 3. Elsevier, pp. P224-237, 2015.
ista: Ori A, Toyama BH, Harris MS, Bock T, Iskar M, Bork P, Ingolia NT, Hetzer M,
Beck M. 2015. Integrated transcriptome and proteome analyses reveal organ-specific
proteome deterioration in old rats. Cell Systems. 1(3), P224-237.
mla: Ori, Alessandro, et al. “Integrated Transcriptome and Proteome Analyses Reveal
Organ-Specific Proteome Deterioration in Old Rats.” Cell Systems, vol.
1, no. 3, Elsevier, 2015, pp. P224-237, doi:10.1016/j.cels.2015.08.012.
short: A. Ori, B.H. Toyama, M.S. Harris, T. Bock, M. Iskar, P. Bork, N.T. Ingolia,
M. Hetzer, M. Beck, Cell Systems 1 (2015) P224-237.
date_created: 2022-04-07T07:49:39Z
date_published: 2015-09-23T00:00:00Z
date_updated: 2022-07-18T08:44:07Z
day: '23'
doi: 10.1016/j.cels.2015.08.012
extern: '1'
external_id:
pmid:
- '27135913'
intvolume: ' 1'
issue: '3'
keyword:
- Cell Biology
- Histology
- Pathology and Forensic Medicine
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cels.2015.08.012
month: '09'
oa: 1
oa_version: Published Version
page: P224-237
pmid: 1
publication: Cell Systems
publication_identifier:
issn:
- 2405-4712
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Integrated transcriptome and proteome analyses reveal organ-specific proteome
deterioration in old rats
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 1
year: '2015'
...