---
_id: '10380'
abstract:
- lang: eng
  text: Using non-equilibrium molecular dynamics simulations, it has been recently
    demonstrated that water molecules align in response to an imposed temperature
    gradient, resulting in an effective electric field. Here, we investigate how thermally
    induced fields depend on the underlying treatment of long-ranged interactions.
    For the short-ranged Wolf method and Ewald summation, we find the peak strength
    of the field to range between 2 × 107 and 5 × 107 V/m for a temperature gradient
    of 5.2 K/Å. Our value for the Wolf method is therefore an order of magnitude lower
    than the literature value [J. A. Armstrong and F. Bresme, J. Chem. Phys. 139,
    014504 (2013); J. Armstrong et al., J. Chem. Phys. 143, 036101 (2015)]. We show
    that this discrepancy can be traced back to the use of an incorrect kernel in
    the calculation of the electrostatic field. More seriously, we find that the Wolf
    method fails to predict correct molecular orientations, resulting in dipole densities
    with opposite sign to those computed using Ewald summation. By considering two
    different multipole expansions, we show that, for inhomogeneous polarisations,
    the quadrupole contribution can be significant and even outweigh the dipole contribution
    to the field. Finally, we propose a more accurate way of calculating the electrostatic
    potential and the field. In particular, we show that averaging the microscopic
    field analytically to obtain the macroscopic Maxwell field reduces the error bars
    by up to an order of magnitude. As a consequence, the simulation times required
    to reach a given statistical accuracy decrease by up to two orders of magnitude.
acknowledgement: The authors should like to dedicate this paper to the memory of Simon
  de Leeuw, who was a pioneer in the calculation of Coulomb effects in simulations.
  P.W. would like to thank the Austrian Academy of Sciences for financial support
  through a DOC Fellowship, and for covering the travel expenses for the CECAM workshop
  in Zaragoza in May 2015, where these results were first presented. P.W. would also
  like to thank Chao Zhang for pointing out the equivalence of the two expressions
  for the electric field discussed in Sec. VI D, Michiel Sprik for emphasising the
  importance of the quadrupole contribution in experimental studies of interfacial
  systems, as well as Aleks Reinhardt and other members of the Frenkel and Dellago
  groups for their advice. We further acknowledge support from the Federation of Austrian
  Industry (IV) Carinthia (P.W.), the University of Zagreb and Erasmus SMP (D. Fijan),
  the Human Frontier Science Program and Emmanuel College (A.Š.), the Austrian Science
  Fund FWF within the SFB Vicom project F41 (C.D.), and the Engineering and Physical
  Sciences Research Council Programme Grant No. EP/I001352/1 (D.F.). Additional data
  related to this publication are available at the University of Cambridge data repository
  (http://dx.doi.org/10.17863/CAM.118).
article_number: '224102'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: P.
  full_name: Wirnsberger, P.
  last_name: Wirnsberger
- first_name: D.
  full_name: Fijan, D.
  last_name: Fijan
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
- first_name: M.
  full_name: Neumann, M.
  last_name: Neumann
- first_name: C.
  full_name: Dellago, C.
  last_name: Dellago
- first_name: D.
  full_name: Frenkel, D.
  last_name: Frenkel
citation:
  ama: Wirnsberger P, Fijan D, Šarić A, Neumann M, Dellago C, Frenkel D. Non-equilibrium
    simulations of thermally induced electric fields in water. <i>The Journal of Chemical
    Physics</i>. 2016;144(22). doi:<a href="https://doi.org/10.1063/1.4953036">10.1063/1.4953036</a>
  apa: Wirnsberger, P., Fijan, D., Šarić, A., Neumann, M., Dellago, C., &#38; Frenkel,
    D. (2016). Non-equilibrium simulations of thermally induced electric fields in
    water. <i>The Journal of Chemical Physics</i>. American Institute of Physics.
    <a href="https://doi.org/10.1063/1.4953036">https://doi.org/10.1063/1.4953036</a>
  chicago: Wirnsberger, P., D. Fijan, Anđela Šarić, M. Neumann, C. Dellago, and D.
    Frenkel. “Non-Equilibrium Simulations of Thermally Induced Electric Fields in
    Water.” <i>The Journal of Chemical Physics</i>. American Institute of Physics,
    2016. <a href="https://doi.org/10.1063/1.4953036">https://doi.org/10.1063/1.4953036</a>.
  ieee: P. Wirnsberger, D. Fijan, A. Šarić, M. Neumann, C. Dellago, and D. Frenkel,
    “Non-equilibrium simulations of thermally induced electric fields in water,” <i>The
    Journal of Chemical Physics</i>, vol. 144, no. 22. American Institute of Physics,
    2016.
  ista: Wirnsberger P, Fijan D, Šarić A, Neumann M, Dellago C, Frenkel D. 2016. Non-equilibrium
    simulations of thermally induced electric fields in water. The Journal of Chemical
    Physics. 144(22), 224102.
  mla: Wirnsberger, P., et al. “Non-Equilibrium Simulations of Thermally Induced Electric
    Fields in Water.” <i>The Journal of Chemical Physics</i>, vol. 144, no. 22, 224102,
    American Institute of Physics, 2016, doi:<a href="https://doi.org/10.1063/1.4953036">10.1063/1.4953036</a>.
  short: P. Wirnsberger, D. Fijan, A. Šarić, M. Neumann, C. Dellago, D. Frenkel, The
    Journal of Chemical Physics 144 (2016).
date_created: 2021-11-29T11:08:52Z
date_published: 2016-06-10T00:00:00Z
date_updated: 2021-11-29T13:09:08Z
day: '10'
doi: 10.1063/1.4953036
extern: '1'
external_id:
  arxiv:
  - '1602.02734'
  pmid:
  - '27305991'
intvolume: '       144'
issue: '22'
keyword:
- physical and theoretical chemistry
- general physics and astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1602.02734
month: '06'
oa: 1
oa_version: Preprint
pmid: 1
publication: The Journal of Chemical Physics
publication_identifier:
  eissn:
  - 1089-7690
  issn:
  - 0021-9606
publication_status: published
publisher: American Institute of Physics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Non-equilibrium simulations of thermally induced electric fields in water
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 144
year: '2016'
...
---
_id: '10381'
abstract:
- lang: eng
  text: We study phase behaviour of lipid-bilayer vesicles functionalised by ligand–receptor
    complexes made of synthetic DNA by introducing a modelling framework and a dedicated
    experimental platform. In particular, we perform Monte Carlo simulations that
    combine a coarse grained description of the lipid bilayer with state of art analytical
    models for multivalent ligand–receptor interactions. Using density of state calculations,
    we derive the partition function in pairs of vesicles and compute the number of
    ligand–receptor bonds as a function of temperature. Numerical results are compared
    to microscopy and fluorimetry experiments on large unilamellar vesicles decorated
    by DNA linkers carrying complementary overhangs. We find that vesicle aggregation
    is suppressed when the total number of linkers falls below a threshold value.
    Within the model proposed here, this is due to the higher configurational costs
    required to form inter-vesicle bridges as compared to intra-vesicle loops, which
    are in turn related to membrane deformability. Our findings and our numerical/experimental
    methodologies are applicable to the rational design of liposomes used as functional
    materials and drug delivery applications, as well as to study inter-membrane interactions
    in living systems, such as cell adhesion.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Stephan Jan
  full_name: Bachmann, Stephan Jan
  last_name: Bachmann
- first_name: Jurij
  full_name: Kotar, Jurij
  last_name: Kotar
- first_name: Lucia
  full_name: Parolini, Lucia
  last_name: Parolini
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
- first_name: Pietro
  full_name: Cicuta, Pietro
  last_name: Cicuta
- first_name: Lorenzo
  full_name: Di Michele, Lorenzo
  last_name: Di Michele
- first_name: Bortolo Matteo
  full_name: Mognetti, Bortolo Matteo
  last_name: Mognetti
citation:
  ama: Bachmann SJ, Kotar J, Parolini L, et al. Melting transition in lipid vesicles
    functionalised by mobile DNA linkers. <i>Soft Matter</i>. 2016;12(37):7804-7817.
    doi:<a href="https://doi.org/10.1039/c6sm01515h">10.1039/c6sm01515h</a>
  apa: Bachmann, S. J., Kotar, J., Parolini, L., Šarić, A., Cicuta, P., Di Michele,
    L., &#38; Mognetti, B. M. (2016). Melting transition in lipid vesicles functionalised
    by mobile DNA linkers. <i>Soft Matter</i>. Royal Society of Chemistry. <a href="https://doi.org/10.1039/c6sm01515h">https://doi.org/10.1039/c6sm01515h</a>
  chicago: Bachmann, Stephan Jan, Jurij Kotar, Lucia Parolini, Anđela Šarić, Pietro
    Cicuta, Lorenzo Di Michele, and Bortolo Matteo Mognetti. “Melting Transition in
    Lipid Vesicles Functionalised by Mobile DNA Linkers.” <i>Soft Matter</i>. Royal
    Society of Chemistry, 2016. <a href="https://doi.org/10.1039/c6sm01515h">https://doi.org/10.1039/c6sm01515h</a>.
  ieee: S. J. Bachmann <i>et al.</i>, “Melting transition in lipid vesicles functionalised
    by mobile DNA linkers,” <i>Soft Matter</i>, vol. 12, no. 37. Royal Society of
    Chemistry, pp. 7804–7817, 2016.
  ista: Bachmann SJ, Kotar J, Parolini L, Šarić A, Cicuta P, Di Michele L, Mognetti
    BM. 2016. Melting transition in lipid vesicles functionalised by mobile DNA linkers.
    Soft Matter. 12(37), 7804–7817.
  mla: Bachmann, Stephan Jan, et al. “Melting Transition in Lipid Vesicles Functionalised
    by Mobile DNA Linkers.” <i>Soft Matter</i>, vol. 12, no. 37, Royal Society of
    Chemistry, 2016, pp. 7804–17, doi:<a href="https://doi.org/10.1039/c6sm01515h">10.1039/c6sm01515h</a>.
  short: S.J. Bachmann, J. Kotar, L. Parolini, A. Šarić, P. Cicuta, L. Di Michele,
    B.M. Mognetti, Soft Matter 12 (2016) 7804–7817.
date_created: 2021-11-29T11:09:55Z
date_published: 2016-08-19T00:00:00Z
date_updated: 2021-11-29T13:09:00Z
day: '19'
doi: 10.1039/c6sm01515h
extern: '1'
external_id:
  arxiv:
  - '1608.05788'
  pmid:
  - '27722701'
intvolume: '        12'
issue: '37'
keyword:
- condensed matter physics
- general chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1608.05788
month: '08'
oa: 1
oa_version: Preprint
page: 7804-7817
pmid: 1
publication: Soft Matter
publication_identifier:
  eissn:
  - 1744-6848
  issn:
  - 1744-683X
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Melting transition in lipid vesicles functionalised by mobile DNA linkers
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 12
year: '2016'
...
---
_id: '1182'
abstract:
- lang: eng
  text: 'Balanced knockout tournaments are ubiquitous in sports competitions and are
    also used in decisionmaking and elections. The traditional computational question,
    that asks to compute a draw (optimal draw) that maximizes the winning probability
    for a distinguished player, has received a lot of attention. Previous works consider
    the problem where the pairwise winning probabilities are known precisely, while
    we study how robust is the winning probability with respect to small errors in
    the pairwise winning probabilities. First, we present several illuminating examples
    to establish: (a) there exist deterministic tournaments (where the pairwise winning
    probabilities are 0 or 1) where one optimal draw is much more robust than the
    other; and (b) in general, there exist tournaments with slightly suboptimal draws
    that are more robust than all the optimal draws. The above examples motivate the
    study of the computational problem of robust draws that guarantee a specified
    winning probability. Second, we present a polynomial-time algorithm for approximating
    the robustness of a draw for sufficiently small errors in pairwise winning probabilities,
    and obtain that the stated computational problem is NP-complete. We also show
    that two natural cases of deterministic tournaments where the optimal draw could
    be computed in polynomial time also admit polynomial-time algorithms to compute
    robust optimal draws.'
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
citation:
  ama: 'Chatterjee K, Ibsen-Jensen R, Tkadlec J. Robust draws in balanced knockout
    tournaments. In: Vol 2016-January. AAAI Press; 2016:172-179.'
  apa: 'Chatterjee, K., Ibsen-Jensen, R., &#38; Tkadlec, J. (2016). Robust draws in
    balanced knockout tournaments (Vol. 2016–January, pp. 172–179). Presented at the
    IJCAI: International Joint Conference on Artificial Intelligence, New York, NY,
    USA: AAAI Press.'
  chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Josef Tkadlec. “Robust
    Draws in Balanced Knockout Tournaments,” 2016–January:172–79. AAAI Press, 2016.
  ieee: 'K. Chatterjee, R. Ibsen-Jensen, and J. Tkadlec, “Robust draws in balanced
    knockout tournaments,” presented at the IJCAI: International Joint Conference
    on Artificial Intelligence, New York, NY, USA, 2016, vol. 2016–January, pp. 172–179.'
  ista: 'Chatterjee K, Ibsen-Jensen R, Tkadlec J. 2016. Robust draws in balanced knockout
    tournaments. IJCAI: International Joint Conference on Artificial Intelligence
    vol. 2016–January, 172–179.'
  mla: Chatterjee, Krishnendu, et al. <i>Robust Draws in Balanced Knockout Tournaments</i>.
    Vol. 2016–January, AAAI Press, 2016, pp. 172–79.
  short: K. Chatterjee, R. Ibsen-Jensen, J. Tkadlec, in:, AAAI Press, 2016, pp. 172–179.
conference:
  end_date: 2016-07-15
  location: New York, NY, USA
  name: 'IJCAI: International Joint Conference on Artificial Intelligence'
  start_date: 2016-07-09
date_created: 2018-12-11T11:50:35Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2023-02-21T10:04:26Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1604.05090v1
month: '01'
oa: 1
oa_version: Preprint
page: 172 - 179
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
publication_status: published
publisher: AAAI Press
publist_id: '6171'
quality_controlled: '1'
related_material:
  link:
  - relation: table_of_contents
    url: https://www.ijcai.org/proceedings/2016
scopus_import: 1
status: public
title: Robust draws in balanced knockout tournaments
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2016-January
year: '2016'
...
---
_id: '1183'
abstract:
- lang: eng
  text: Autism spectrum disorders (ASD) are a group of genetic disorders often overlapping
    with other neurological conditions. We previously described abnormalities in the
    branched-chain amino acid (BCAA) catabolic pathway as a cause of ASD. Here, we
    show that the solute carrier transporter 7a5 (SLC7A5), a large neutral amino acid
    transporter localized at the blood brain barrier (BBB), has an essential role
    in maintaining normal levels of brain BCAAs. In mice, deletion of Slc7a5 from
    the endothelial cells of the BBB leads to atypical brain amino acid profile, abnormal
    mRNA translation, and severe neurological abnormalities. Furthermore, we identified
    several patients with autistic traits and motor delay carrying deleterious homozygous
    mutations in the SLC7A5 gene. Finally, we demonstrate that BCAA intracerebroventricular
    administration ameliorates abnormal behaviors in adult mutant mice. Our data elucidate
    a neurological syndrome defined by SLC7A5 mutations and support an essential role
    for the BCAA in human brain function.
acknowledgement: "This work was supported by NICHD (P01HD070494) and SFARI (grant
  275275) to J.G.G., and FWF (SFB35_3523) to G.N.\r\nWe thank A.C. Manzano, Mike Liu,
  and F. Marr for technical assistance, and R. Shigemoto and the IST Austria Electron
  Microscopy (EM) Facility for assistance. We acknowledge support from CIDR for genome-wide
  SNP analysis (X01HG008823) and Broad Institute Center for Mendelian Disorders (UM1HG008900
  to D. MacArthur), the Yale Center for Mendelian Disorders (U54HG006504 to M.G.),
  the Gregory M. Kiez and Mehmet Kutman Foundation (M.G.), Italian Ministry of Instruction
  University and Research (PON01_00937 to C.I.), and NIH (R01-GM108911 to A.S.). This
  work was supported by NICHD (P01HD070494) and SFARI (grant 275275) to J.G.G., and
  FWF (SFB35_3523) to G.N.\r\n\r\n#EMFacility"
article_processing_charge: No
article_type: original
author:
- first_name: Dora-Clara
  full_name: Tarlungeanu, Dora-Clara
  id: 2ABCE612-F248-11E8-B48F-1D18A9856A87
  last_name: Tarlungeanu
- first_name: Elena
  full_name: Deliu, Elena
  id: 37A40D7E-F248-11E8-B48F-1D18A9856A87
  last_name: Deliu
  orcid: 0000-0002-7370-5293
- first_name: Christoph
  full_name: Dotter, Christoph
  id: 4C66542E-F248-11E8-B48F-1D18A9856A87
  last_name: Dotter
  orcid: 0000-0002-9033-9096
- first_name: Majdi
  full_name: Kara, Majdi
  last_name: Kara
- first_name: Philipp
  full_name: Janiesch, Philipp
  last_name: Janiesch
- first_name: Mariafrancesca
  full_name: Scalise, Mariafrancesca
  last_name: Scalise
- first_name: Michele
  full_name: Galluccio, Michele
  last_name: Galluccio
- first_name: Mateja
  full_name: Tesulov, Mateja
  last_name: Tesulov
- first_name: Emanuela
  full_name: Morelli, Emanuela
  id: 3F4D1282-F248-11E8-B48F-1D18A9856A87
  last_name: Morelli
- first_name: Fatma
  full_name: Sönmez, Fatma
  last_name: Sönmez
- first_name: Kaya
  full_name: Bilgüvar, Kaya
  last_name: Bilgüvar
- first_name: Ryuichi
  full_name: Ohgaki, Ryuichi
  last_name: Ohgaki
- first_name: Yoshikatsu
  full_name: Kanai, Yoshikatsu
  last_name: Kanai
- first_name: Anide
  full_name: Johansen, Anide
  last_name: Johansen
- first_name: Seham
  full_name: Esharif, Seham
  last_name: Esharif
- first_name: Tawfeg
  full_name: Ben Omran, Tawfeg
  last_name: Ben Omran
- first_name: Meral
  full_name: Topcu, Meral
  last_name: Topcu
- first_name: Avner
  full_name: Schlessinger, Avner
  last_name: Schlessinger
- first_name: Cesare
  full_name: Indiveri, Cesare
  last_name: Indiveri
- first_name: Kent
  full_name: Duncan, Kent
  last_name: Duncan
- first_name: Ahmet
  full_name: Caglayan, Ahmet
  last_name: Caglayan
- first_name: Murat
  full_name: Günel, Murat
  last_name: Günel
- first_name: Joseph
  full_name: Gleeson, Joseph
  last_name: Gleeson
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
citation:
  ama: Tarlungeanu D-C, Deliu E, Dotter C, et al. Impaired amino acid transport at
    the blood brain barrier is a cause of autism spectrum disorder. <i>Cell</i>. 2016;167(6):1481-1494.
    doi:<a href="https://doi.org/10.1016/j.cell.2016.11.013">10.1016/j.cell.2016.11.013</a>
  apa: Tarlungeanu, D.-C., Deliu, E., Dotter, C., Kara, M., Janiesch, P., Scalise,
    M., … Novarino, G. (2016). Impaired amino acid transport at the blood brain barrier
    is a cause of autism spectrum disorder. <i>Cell</i>. Cell Press. <a href="https://doi.org/10.1016/j.cell.2016.11.013">https://doi.org/10.1016/j.cell.2016.11.013</a>
  chicago: Tarlungeanu, Dora-Clara, Elena Deliu, Christoph Dotter, Majdi Kara, Philipp
    Janiesch, Mariafrancesca Scalise, Michele Galluccio, et al. “Impaired Amino Acid
    Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder.”
    <i>Cell</i>. Cell Press, 2016. <a href="https://doi.org/10.1016/j.cell.2016.11.013">https://doi.org/10.1016/j.cell.2016.11.013</a>.
  ieee: D.-C. Tarlungeanu <i>et al.</i>, “Impaired amino acid transport at the blood
    brain barrier is a cause of autism spectrum disorder,” <i>Cell</i>, vol. 167,
    no. 6. Cell Press, pp. 1481–1494, 2016.
  ista: Tarlungeanu D-C, Deliu E, Dotter C, Kara M, Janiesch P, Scalise M, Galluccio
    M, Tesulov M, Morelli E, Sönmez F, Bilgüvar K, Ohgaki R, Kanai Y, Johansen A,
    Esharif S, Ben Omran T, Topcu M, Schlessinger A, Indiveri C, Duncan K, Caglayan
    A, Günel M, Gleeson J, Novarino G. 2016. Impaired amino acid transport at the
    blood brain barrier is a cause of autism spectrum disorder. Cell. 167(6), 1481–1494.
  mla: Tarlungeanu, Dora-Clara, et al. “Impaired Amino Acid Transport at the Blood
    Brain Barrier Is a Cause of Autism Spectrum Disorder.” <i>Cell</i>, vol. 167,
    no. 6, Cell Press, 2016, pp. 1481–94, doi:<a href="https://doi.org/10.1016/j.cell.2016.11.013">10.1016/j.cell.2016.11.013</a>.
  short: D.-C. Tarlungeanu, E. Deliu, C. Dotter, M. Kara, P. Janiesch, M. Scalise,
    M. Galluccio, M. Tesulov, E. Morelli, F. Sönmez, K. Bilgüvar, R. Ohgaki, Y. Kanai,
    A. Johansen, S. Esharif, T. Ben Omran, M. Topcu, A. Schlessinger, C. Indiveri,
    K. Duncan, A. Caglayan, M. Günel, J. Gleeson, G. Novarino, Cell 167 (2016) 1481–1494.
date_created: 2018-12-11T11:50:35Z
date_published: 2016-12-01T00:00:00Z
date_updated: 2024-03-25T23:30:07Z
day: '01'
ddc:
- '576'
- '616'
department:
- _id: GaNo
doi: 10.1016/j.cell.2016.11.013
file:
- access_level: open_access
  checksum: 7fe01ab12a6610d3db421e0136db2f77
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:44Z
  date_updated: 2020-07-14T12:44:37Z
  file_id: '5030'
  file_name: IST-2017-771-v1+1_Tarlungeanu_et_al._Final_edited.pdf
  file_size: 73907957
  relation: main_file
file_date_updated: 2020-07-14T12:44:37Z
has_accepted_license: '1'
intvolume: '       167'
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
page: 1481 - 1494
project:
- _id: 25473368-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: F03523
  name: Transmembrane Transporters in Health and Disease
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '6170'
pubrep_id: '771'
quality_controlled: '1'
related_material:
  record:
  - id: '395'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Impaired amino acid transport at the blood brain barrier is a cause of autism
  spectrum disorder
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 167
year: '2016'
...
---
_id: '11834'
abstract:
- lang: eng
  text: "We present a deterministic incremental algorithm for exactly maintaining
    the size of a minimum cut with ~O(1) amortized time per edge insertion and O(1)
    query time. This result partially answers an open question posed by Thorup [Combinatorica
    2007]. It also stays in sharp contrast to a polynomial conditional lower-bound
    for the fully-dynamic weighted minimum cut problem. Our algorithm is obtained
    by combining a recent sparsification technique of Kawarabayashi and Thorup [STOC
    2015] and an exact incremental algorithm of Henzinger [J. of Algorithm 1997].\r\n\r\nWe
    also study space-efficient incremental algorithms for the minimum cut problem.
    Concretely, we show that there exists an O(n log n/epsilon^2) space Monte-Carlo
    algorithm that can process a stream of edge insertions starting from an empty
    graph, and with high probability, the algorithm maintains a (1+epsilon)-approximation
    to the minimum cut. The algorithm has ~O(1) amortized update-time and constant
    query-time."
alternative_title:
- LIPIcs
article_number: '46'
article_processing_charge: No
arxiv: 1
author:
- first_name: Gramoz
  full_name: Goranci, Gramoz
  last_name: Goranci
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Mikkel
  full_name: Thorup, Mikkel
  last_name: Thorup
citation:
  ama: 'Goranci G, Henzinger MH, Thorup M. Incremental exact min-cut in poly-logarithmic
    amortized update time. In: <i>24th Annual European Symposium on Algorithms</i>.
    Vol 57. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2016. doi:<a href="https://doi.org/10.4230/LIPICS.ESA.2016.46">10.4230/LIPICS.ESA.2016.46</a>'
  apa: 'Goranci, G., Henzinger, M. H., &#38; Thorup, M. (2016). Incremental exact
    min-cut in poly-logarithmic amortized update time. In <i>24th Annual European
    Symposium on Algorithms</i> (Vol. 57). Aarhus, Denmark: Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik. <a href="https://doi.org/10.4230/LIPICS.ESA.2016.46">https://doi.org/10.4230/LIPICS.ESA.2016.46</a>'
  chicago: Goranci, Gramoz, Monika H Henzinger, and Mikkel Thorup. “Incremental Exact
    Min-Cut in Poly-Logarithmic Amortized Update Time.” In <i>24th Annual European
    Symposium on Algorithms</i>, Vol. 57. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2016. <a href="https://doi.org/10.4230/LIPICS.ESA.2016.46">https://doi.org/10.4230/LIPICS.ESA.2016.46</a>.
  ieee: G. Goranci, M. H. Henzinger, and M. Thorup, “Incremental exact min-cut in
    poly-logarithmic amortized update time,” in <i>24th Annual European Symposium
    on Algorithms</i>, Aarhus, Denmark, 2016, vol. 57.
  ista: 'Goranci G, Henzinger MH, Thorup M. 2016. Incremental exact min-cut in poly-logarithmic
    amortized update time. 24th Annual European Symposium on Algorithms. ESA: Annual
    European Symposium on Algorithms, LIPIcs, vol. 57, 46.'
  mla: Goranci, Gramoz, et al. “Incremental Exact Min-Cut in Poly-Logarithmic Amortized
    Update Time.” <i>24th Annual European Symposium on Algorithms</i>, vol. 57, 46,
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016, doi:<a href="https://doi.org/10.4230/LIPICS.ESA.2016.46">10.4230/LIPICS.ESA.2016.46</a>.
  short: G. Goranci, M.H. Henzinger, M. Thorup, in:, 24th Annual European Symposium
    on Algorithms, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016.
conference:
  end_date: 2016-08-24
  location: Aarhus, Denmark
  name: 'ESA: Annual European Symposium on Algorithms'
  start_date: 2016-08-22
date_created: 2022-08-12T10:58:32Z
date_published: 2016-08-18T00:00:00Z
date_updated: 2023-02-16T12:05:59Z
day: '18'
doi: 10.4230/LIPICS.ESA.2016.46
extern: '1'
external_id:
  arxiv:
  - '1611.06500'
intvolume: '        57'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.4230/LIPIcs.ESA.2016.46
month: '08'
oa: 1
oa_version: Published Version
publication: 24th Annual European Symposium on Algorithms
publication_identifier:
  isbn:
  - 978-3-95977-015-6
  issn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: Incremental exact min-cut in poly-logarithmic amortized update time
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 57
year: '2016'
...
---
_id: '11835'
abstract:
- lang: eng
  text: "During the last 10 years it has become popular to study dynamic graph problems
    in a emergency planning or sensitivity setting: Instead of considering the general
    fully dynamic problem, we only have to process a single batch update of size d;
    after the update we have to answer queries.\r\n\r\nIn this paper, we consider
    the dynamic subgraph connectivity problem with sensitivity d: We are given a graph
    of which some vertices are activated and some are deactivated. After that we get
    a single update in which the states of up to $d$ vertices are changed. Then we
    get a sequence of connectivity queries in the subgraph of activated vertices.\r\n\r\nWe
    present the first fully dynamic algorithm for this problem which has an update
    and query time only slightly worse than the best decremental algorithm. In addition,
    we present the first incremental algorithm which is tight with respect to the
    best known conditional lower bound; moreover, the algorithm is simple and we believe
    it is implementable and efficient in practice."
alternative_title:
- LIPIcs
article_number: '48'
article_processing_charge: No
arxiv: 1
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Stefan
  full_name: Neumann, Stefan
  last_name: Neumann
citation:
  ama: 'Henzinger MH, Neumann S. Incremental and fully dynamic subgraph connectivity
    for emergency planning. In: <i>24th Annual European Symposium on Algorithms</i>.
    Vol 57. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2016. doi:<a href="https://doi.org/10.4230/LIPICS.ESA.2016.48">10.4230/LIPICS.ESA.2016.48</a>'
  apa: 'Henzinger, M. H., &#38; Neumann, S. (2016). Incremental and fully dynamic
    subgraph connectivity for emergency planning. In <i>24th Annual European Symposium
    on Algorithms</i> (Vol. 57). Aarhus, Denmark: Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik. <a href="https://doi.org/10.4230/LIPICS.ESA.2016.48">https://doi.org/10.4230/LIPICS.ESA.2016.48</a>'
  chicago: Henzinger, Monika H, and Stefan Neumann. “Incremental and Fully Dynamic
    Subgraph Connectivity for Emergency Planning.” In <i>24th Annual European Symposium
    on Algorithms</i>, Vol. 57. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2016. <a href="https://doi.org/10.4230/LIPICS.ESA.2016.48">https://doi.org/10.4230/LIPICS.ESA.2016.48</a>.
  ieee: M. H. Henzinger and S. Neumann, “Incremental and fully dynamic subgraph connectivity
    for emergency planning,” in <i>24th Annual European Symposium on Algorithms</i>,
    Aarhus, Denmark, 2016, vol. 57.
  ista: 'Henzinger MH, Neumann S. 2016. Incremental and fully dynamic subgraph connectivity
    for emergency planning. 24th Annual European Symposium on Algorithms. ESA: Annual
    European Symposium on Algorithms, LIPIcs, vol. 57, 48.'
  mla: Henzinger, Monika H., and Stefan Neumann. “Incremental and Fully Dynamic Subgraph
    Connectivity for Emergency Planning.” <i>24th Annual European Symposium on Algorithms</i>,
    vol. 57, 48, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016, doi:<a href="https://doi.org/10.4230/LIPICS.ESA.2016.48">10.4230/LIPICS.ESA.2016.48</a>.
  short: M.H. Henzinger, S. Neumann, in:, 24th Annual European Symposium on Algorithms,
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016.
conference:
  end_date: 2016-08-24
  location: Aarhus, Denmark
  name: 'ESA: Annual European Symposium on Algorithms'
  start_date: 2016-08-22
date_created: 2022-08-12T11:05:41Z
date_published: 2016-08-18T00:00:00Z
date_updated: 2023-02-16T12:07:46Z
day: '18'
doi: 10.4230/LIPICS.ESA.2016.48
extern: '1'
external_id:
  arxiv:
  - '1611.05248'
intvolume: '        57'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.4230/LIPIcs.ESA.2016.48
month: '08'
oa: 1
oa_version: Published Version
publication: 24th Annual European Symposium on Algorithms
publication_identifier:
  isbn:
  - 978-3-95977-015-6
  issn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: Incremental and fully dynamic subgraph connectivity for emergency planning
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 57
year: '2016'
...
---
_id: '11836'
abstract:
- lang: eng
  text: "Given a graph where vertices are partitioned into k terminals and non-terminals,
    the goal is to compress the graph (i.e., reduce the number of non-terminals) using
    minor operations while preserving terminal distances approximately. The distortion
    of a compressed graph is the maximum multiplicative blow-up of distances between
    all pairs of terminals. We study the trade-off between the number of non-terminals
    and the distortion. This problem generalizes the Steiner Point Removal (SPR) problem,
    in which all non-terminals must be removed.\r\n\r\nWe introduce a novel black-box
    reduction to convert any lower bound on distortion for the SPR problem into a
    super-linear lower bound on the number of non-terminals, with the same distortion,
    for our problem. This allows us to show that there exist graphs such that every
    minor with distortion less than 2 / 2.5 / 3 must have Omega(k^2) / Omega(k^{5/4})
    / Omega(k^{6/5}) non-terminals, plus more trade-offs in between. The black-box
    reduction has an interesting consequence: if the tight lower bound on distortion
    for the SPR problem is super-constant, then allowing any O(k) non-terminals will
    not help improving the lower bound to a constant.\r\n\r\nWe also build on the
    existing results on spanners, distance oracles and connected 0-extensions to show
    a number of upper bounds for general graphs, planar graphs, graphs that exclude
    a fixed minor and bounded treewidth graphs. Among others, we show that any graph
    admits a minor with O(log k) distortion and O(k^2) non-terminals, and any planar
    graph admits a minor with\r\n1 + epsilon distortion and ~O((k/epsilon)^2) non-terminals."
alternative_title:
- LIPIcs
article_number: '131'
article_processing_charge: No
arxiv: 1
author:
- first_name: Yun Kuen
  full_name: Cheung, Yun Kuen
  last_name: Cheung
- first_name: Gramoz
  full_name: Goranci, Gramoz
  last_name: Goranci
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
citation:
  ama: 'Cheung YK, Goranci G, Henzinger MH. Graph minors for preserving terminal distances
    approximately - lower and upper bounds. In: <i>43rd International Colloquium on
    Automata, Languages, and Programming</i>. Vol 55. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik; 2016. doi:<a href="https://doi.org/10.4230/LIPICS.ICALP.2016.131">10.4230/LIPICS.ICALP.2016.131</a>'
  apa: 'Cheung, Y. K., Goranci, G., &#38; Henzinger, M. H. (2016). Graph minors for
    preserving terminal distances approximately - lower and upper bounds. In <i>43rd
    International Colloquium on Automata, Languages, and Programming</i> (Vol. 55).
    Rome, Italy: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPICS.ICALP.2016.131">https://doi.org/10.4230/LIPICS.ICALP.2016.131</a>'
  chicago: Cheung, Yun Kuen, Gramoz Goranci, and Monika H Henzinger. “Graph Minors
    for Preserving Terminal Distances Approximately - Lower and Upper Bounds.” In
    <i>43rd International Colloquium on Automata, Languages, and Programming</i>,
    Vol. 55. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016. <a href="https://doi.org/10.4230/LIPICS.ICALP.2016.131">https://doi.org/10.4230/LIPICS.ICALP.2016.131</a>.
  ieee: Y. K. Cheung, G. Goranci, and M. H. Henzinger, “Graph minors for preserving
    terminal distances approximately - lower and upper bounds,” in <i>43rd International
    Colloquium on Automata, Languages, and Programming</i>, Rome, Italy, 2016, vol.
    55.
  ista: 'Cheung YK, Goranci G, Henzinger MH. 2016. Graph minors for preserving terminal
    distances approximately - lower and upper bounds. 43rd International Colloquium
    on Automata, Languages, and Programming. ICALP: International Colloquium on Automata,
    Languages, and Programming, LIPIcs, vol. 55, 131.'
  mla: Cheung, Yun Kuen, et al. “Graph Minors for Preserving Terminal Distances Approximately
    - Lower and Upper Bounds.” <i>43rd International Colloquium on Automata, Languages,
    and Programming</i>, vol. 55, 131, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2016, doi:<a href="https://doi.org/10.4230/LIPICS.ICALP.2016.131">10.4230/LIPICS.ICALP.2016.131</a>.
  short: Y.K. Cheung, G. Goranci, M.H. Henzinger, in:, 43rd International Colloquium
    on Automata, Languages, and Programming, Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2016.
conference:
  end_date: 2016-07-15
  location: Rome, Italy
  name: 'ICALP: International Colloquium on Automata, Languages, and Programming'
  start_date: 2016-07-12
date_created: 2022-08-12T11:16:01Z
date_published: 2016-08-23T00:00:00Z
date_updated: 2023-02-16T12:09:54Z
day: '23'
doi: 10.4230/LIPICS.ICALP.2016.131
extern: '1'
external_id:
  arxiv:
  - '1604.08342'
intvolume: '        55'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.4230/LIPICS.ICALP.2016.131
month: '08'
oa: 1
oa_version: Published Version
publication: 43rd International Colloquium on Automata, Languages, and Programming
publication_identifier:
  isbn:
  - 978-3-95977-013-2
  issn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: Graph minors for preserving terminal distances approximately - lower and upper
  bounds
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2016'
...
---
_id: '1184'
abstract:
- lang: eng
  text: Across multicellular organisms, the costs of reproduction and self-maintenance
    result in a life history trade-off between fecundity and longevity. Queens of
    perennial social Hymenoptera are both highly fertile and long-lived, and thus,
    this fundamental trade-off is lacking. Whether social insect males similarly evade
    the fecundity/longevity trade-off remains largely unstudied. Wingless males of
    the ant genus Cardiocondyla stay in their natal colonies throughout their relatively
    long lives and mate with multiple female sexuals. Here, we show that Cardiocondyla
    obscurior males that were allowed to mate with large numbers of female sexuals
    had a shortened life span compared to males that mated at a low frequency or virgin
    males. Although frequent mating negatively affects longevity, males clearly benefit
    from a “live fast, die young strategy” by inseminating as many female sexuals
    as possible at a cost to their own survival.
acknowledgement: 'German Science Foundation. Grant Number: SCHR 1135/2-1. We thank
  M. Adam for handling part of the setups and J. Zoellner for behavioral observations.'
author:
- first_name: Sina
  full_name: Metzler, Sina
  id: 48204546-F248-11E8-B48F-1D18A9856A87
  last_name: Metzler
- first_name: Jürgen
  full_name: Heinze, Jürgen
  last_name: Heinze
- first_name: Alexandra
  full_name: Schrempf, Alexandra
  last_name: Schrempf
citation:
  ama: Metzler S, Heinze J, Schrempf A. Mating and longevity in ant males. <i>Ecology
    and Evolution</i>. 2016;6(24):8903-8906. doi:<a href="https://doi.org/10.1002/ece3.2474">10.1002/ece3.2474</a>
  apa: Metzler, S., Heinze, J., &#38; Schrempf, A. (2016). Mating and longevity in
    ant males. <i>Ecology and Evolution</i>. Wiley-Blackwell. <a href="https://doi.org/10.1002/ece3.2474">https://doi.org/10.1002/ece3.2474</a>
  chicago: Metzler, Sina, Jürgen Heinze, and Alexandra Schrempf. “Mating and Longevity
    in Ant Males.” <i>Ecology and Evolution</i>. Wiley-Blackwell, 2016. <a href="https://doi.org/10.1002/ece3.2474">https://doi.org/10.1002/ece3.2474</a>.
  ieee: S. Metzler, J. Heinze, and A. Schrempf, “Mating and longevity in ant males,”
    <i>Ecology and Evolution</i>, vol. 6, no. 24. Wiley-Blackwell, pp. 8903–8906,
    2016.
  ista: Metzler S, Heinze J, Schrempf A. 2016. Mating and longevity in ant males.
    Ecology and Evolution. 6(24), 8903–8906.
  mla: Metzler, Sina, et al. “Mating and Longevity in Ant Males.” <i>Ecology and Evolution</i>,
    vol. 6, no. 24, Wiley-Blackwell, 2016, pp. 8903–06, doi:<a href="https://doi.org/10.1002/ece3.2474">10.1002/ece3.2474</a>.
  short: S. Metzler, J. Heinze, A. Schrempf, Ecology and Evolution 6 (2016) 8903–8906.
date_created: 2018-12-11T11:50:36Z
date_published: 2016-12-01T00:00:00Z
date_updated: 2021-01-12T06:48:55Z
day: '01'
ddc:
- '576'
- '592'
department:
- _id: SyCr
doi: 10.1002/ece3.2474
file:
- access_level: open_access
  checksum: 789026eb9e1be2a0da08376f29f569cf
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:12Z
  date_updated: 2020-07-14T12:44:37Z
  file_id: '5062'
  file_name: IST-2017-736-v1+1_Metzler_et_al-2016-Ecology_and_Evolution.pdf
  file_size: 328414
  relation: main_file
file_date_updated: 2020-07-14T12:44:37Z
has_accepted_license: '1'
intvolume: '         6'
issue: '24'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 8903 - 8906
publication: Ecology and Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '6169'
pubrep_id: '736'
quality_controlled: '1'
scopus_import: 1
status: public
title: Mating and longevity in ant males
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2016'
...
---
_id: '1186'
abstract:
- lang: eng
  text: The human pathogen Streptococcus pneumoniae is decorated with a special class
    of surface-proteins known as choline-binding proteins (CBPs) attached to phosphorylcholine
    (PCho) moieties from cell-wall teichoic acids. By a combination of X-ray crystallography,
    NMR, molecular dynamics techniques and in vivo virulence and phagocytosis studies,
    we provide structural information of choline-binding protein L (CbpL) and demonstrate
    its impact on pneumococcal pathogenesis and immune evasion. CbpL is a very elongated
    three-module protein composed of (i) an Excalibur Ca 2+ -binding domain -reported
    in this work for the very first time-, (ii) an unprecedented anchorage module
    showing alternate disposition of canonical and non-canonical choline-binding sites
    that allows vine-like binding of fully-PCho-substituted teichoic acids (with two
    choline moieties per unit), and (iii) a Ltp-Lipoprotein domain. Our structural
    and infection assays indicate an important role of the whole multimodular protein
    allowing both to locate CbpL at specific places on the cell wall and to interact
    with host components in order to facilitate pneumococcal lung infection and transmigration
    from nasopharynx to the lungs and blood. CbpL implication in both resistance against
    killing by phagocytes and pneumococcal pathogenesis further postulate this surface-protein
    as relevant among the pathogenic arsenal of the pneumococcus.
acknowledgement: We gratefully acknowledge Karsta Barnekow and Kristine Sievert-Giermann,
  for technical assistance and Lothar Petruschka for in silico analysis (all Dept.
  of Genetics, University of Greifswald). We are further grateful to the staff from
  SLS synchrotron beamline for help in data collection. This work was supported by
  grants from the Deutsche Forschungsgemeinschaft DFG GRK 1870 (to SH) and the Spanish
  Ministry of Economy and Competitiveness (BFU2014-59389-P to JAH, CTQ2014-52633-P
  to MB and SAF2012-39760-C02-02 to FG) and S2010/BMD-2457 (Community of Madrid to
  JAH and FG).
article_number: '38094'
author:
- first_name: Javier
  full_name: Gutierrez-Fernandez, Javier
  id: 3D9511BA-F248-11E8-B48F-1D18A9856A87
  last_name: Gutierrez-Fernandez
- first_name: Malek
  full_name: Saleh, Malek
  last_name: Saleh
- first_name: Martín
  full_name: Alcorlo, Martín
  last_name: Alcorlo
- first_name: Alejandro
  full_name: Gómez Mejóa, Alejandro
  last_name: Gómez Mejóa
- first_name: David
  full_name: Pantoja Uceda, David
  last_name: Pantoja Uceda
- first_name: Miguel
  full_name: Treviño, Miguel
  last_name: Treviño
- first_name: Franziska
  full_name: Vob, Franziska
  last_name: Vob
- first_name: Mohammed
  full_name: Abdullah, Mohammed
  last_name: Abdullah
- first_name: Sergio
  full_name: Galán Bartual, Sergio
  last_name: Galán Bartual
- first_name: Jolien
  full_name: Seinen, Jolien
  last_name: Seinen
- first_name: Pedro
  full_name: Sánchez Murcia, Pedro
  last_name: Sánchez Murcia
- first_name: Federico
  full_name: Gago, Federico
  last_name: Gago
- first_name: Marta
  full_name: Bruix, Marta
  last_name: Bruix
- first_name: Sven
  full_name: Hammerschmidt, Sven
  last_name: Hammerschmidt
- first_name: Juan
  full_name: Hermoso, Juan
  last_name: Hermoso
citation:
  ama: Gutierrez-Fernandez J, Saleh M, Alcorlo M, et al. Modular architecture and
    unique teichoic acid recognition features of choline-binding protein L CbpL contributing
    to pneumococcal pathogenesis. <i>Scientific Reports</i>. 2016;6. doi:<a href="https://doi.org/10.1038/srep38094">10.1038/srep38094</a>
  apa: Gutierrez-Fernandez, J., Saleh, M., Alcorlo, M., Gómez Mejóa, A., Pantoja Uceda,
    D., Treviño, M., … Hermoso, J. (2016). Modular architecture and unique teichoic
    acid recognition features of choline-binding protein L CbpL contributing to pneumococcal
    pathogenesis. <i>Scientific Reports</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/srep38094">https://doi.org/10.1038/srep38094</a>
  chicago: Gutierrez-Fernandez, Javier, Malek Saleh, Martín Alcorlo, Alejandro Gómez
    Mejóa, David Pantoja Uceda, Miguel Treviño, Franziska Vob, et al. “Modular Architecture
    and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L CbpL
    Contributing to Pneumococcal Pathogenesis.” <i>Scientific Reports</i>. Nature
    Publishing Group, 2016. <a href="https://doi.org/10.1038/srep38094">https://doi.org/10.1038/srep38094</a>.
  ieee: J. Gutierrez-Fernandez <i>et al.</i>, “Modular architecture and unique teichoic
    acid recognition features of choline-binding protein L CbpL contributing to pneumococcal
    pathogenesis,” <i>Scientific Reports</i>, vol. 6. Nature Publishing Group, 2016.
  ista: Gutierrez-Fernandez J, Saleh M, Alcorlo M, Gómez Mejóa A, Pantoja Uceda D,
    Treviño M, Vob F, Abdullah M, Galán Bartual S, Seinen J, Sánchez Murcia P, Gago
    F, Bruix M, Hammerschmidt S, Hermoso J. 2016. Modular architecture and unique
    teichoic acid recognition features of choline-binding protein L CbpL contributing
    to pneumococcal pathogenesis. Scientific Reports. 6, 38094.
  mla: Gutierrez-Fernandez, Javier, et al. “Modular Architecture and Unique Teichoic
    Acid Recognition Features of Choline-Binding Protein L CbpL Contributing to Pneumococcal
    Pathogenesis.” <i>Scientific Reports</i>, vol. 6, 38094, Nature Publishing Group,
    2016, doi:<a href="https://doi.org/10.1038/srep38094">10.1038/srep38094</a>.
  short: J. Gutierrez-Fernandez, M. Saleh, M. Alcorlo, A. Gómez Mejóa, D. Pantoja
    Uceda, M. Treviño, F. Vob, M. Abdullah, S. Galán Bartual, J. Seinen, P. Sánchez
    Murcia, F. Gago, M. Bruix, S. Hammerschmidt, J. Hermoso, Scientific Reports 6
    (2016).
date_created: 2018-12-11T11:50:36Z
date_published: 2016-12-05T00:00:00Z
date_updated: 2021-01-12T06:48:56Z
day: '05'
ddc:
- '576'
- '610'
department:
- _id: LeSa
doi: 10.1038/srep38094
file:
- access_level: open_access
  checksum: e007d78b483bc59bf5ab98e9d42a6ec1
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:18Z
  date_updated: 2020-07-14T12:44:37Z
  file_id: '4804'
  file_name: IST-2017-735-v1+1_srep38094.pdf
  file_size: 2716045
  relation: main_file
file_date_updated: 2020-07-14T12:44:37Z
has_accepted_license: '1'
intvolume: '         6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: Scientific Reports
publication_status: published
publisher: Nature Publishing Group
publist_id: '6167'
pubrep_id: '735'
quality_controlled: '1'
scopus_import: 1
status: public
title: Modular architecture and unique teichoic acid recognition features of choline-binding
  protein L CbpL contributing to pneumococcal pathogenesis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2016'
...
---
_id: '11866'
abstract:
- lang: eng
  text: "We present a deterministic (1+o(1))-approximation O(n1/2+o(1)+D1+o(1))-time
    algorithm for solving the single-source shortest paths problem on distributed
    weighted networks (the CONGEST model); here n is the number of nodes in the network
    and D is its (hop) diameter. This is the first non-trivial deterministic algorithm
    for this problem. It also improves (i) the running time of the randomized (1+o(1))-approximation
    Õ(n1/2D1/4+D)-time algorithm of Nanongkai [STOC 2014] by a factor of as large
    as n1/8, and (ii) the O(є−1logє−1)-approximation factor of Lenzen and Patt-Shamir’s
    Õ(n1/2+є+D)-time algorithm [STOC 2013] within the same running time. Our running
    time matches the known time lower bound of Ω(n1/2/logn + D) [Das Sarma et al.
    STOC 2011] modulo some lower-order terms, thus essentially settling the status
    of this problem which was raised at least a decade ago [Elkin SIGACT News 2004].
    It also implies a (2+o(1))-approximation O(n1/2+o(1)+D1+o(1))-time algorithm for
    approximating a network’s weighted diameter which almost matches the lower bound
    by Holzer et al. [PODC 2012].\r\n\r\nIn achieving this result, we develop two
    techniques which might be of independent interest and useful in other settings:
    (i) a deterministic process that replaces the “hitting set argument” commonly
    used for shortest paths computation in various settings, and (ii) a simple, deterministic,
    construction of an (no(1), o(1))-hop set of size O(n1+o(1)). We combine these
    techniques with many distributed algorithmic techniques, some of which from problems
    that are not directly related to shortest paths, e.g. ruling sets [Goldberg et
    al. STOC 1987], source detection [Lenzen, Peleg PODC 2013], and partial distance
    estimation [Lenzen, Patt-Shamir PODC 2015]. Our hop set construction also leads
    to single-source shortest paths algorithms in two other settings: (i) a (1+o(1))-approximation
    O(no(1))-time algorithm on congested cliques, and (ii) a (1+o(1))-approximation
    O(no(1)logW)-pass O(n1+o(1)logW)-space streaming algorithm, when edge weights
    are in {1, 2, …, W}. The first result answers an open problem in [Nanongkai, STOC
    2014]. The second result partially answers an open problem raised by McGregor
    in 2006 [<pre>sublinear.info</pre>, Problem 14]."
article_processing_charge: No
arxiv: 1
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Sebastian
  full_name: Krinninger, Sebastian
  last_name: Krinninger
- first_name: Danupon
  full_name: Nanongkai, Danupon
  last_name: Nanongkai
citation:
  ama: 'Henzinger MH, Krinninger S, Nanongkai D. A deterministic almost-tight distributed
    algorithm for approximating single-source shortest paths. In: <i>48th Annual ACM
    SIGACT Symposium on Theory of Computing</i>. Association for Computing Machinery;
    2016:489-498. doi:<a href="https://doi.org/10.1145/2897518.2897638">10.1145/2897518.2897638</a>'
  apa: 'Henzinger, M. H., Krinninger, S., &#38; Nanongkai, D. (2016). A deterministic
    almost-tight distributed algorithm for approximating single-source shortest paths.
    In <i>48th Annual ACM SIGACT Symposium on Theory of Computing</i> (pp. 489–498).
    Cambridge, MA, United States: Association for Computing Machinery. <a href="https://doi.org/10.1145/2897518.2897638">https://doi.org/10.1145/2897518.2897638</a>'
  chicago: Henzinger, Monika H, Sebastian Krinninger, and Danupon Nanongkai. “A Deterministic
    Almost-Tight Distributed Algorithm for Approximating Single-Source Shortest Paths.”
    In <i>48th Annual ACM SIGACT Symposium on Theory of Computing</i>, 489–98. Association
    for Computing Machinery, 2016. <a href="https://doi.org/10.1145/2897518.2897638">https://doi.org/10.1145/2897518.2897638</a>.
  ieee: M. H. Henzinger, S. Krinninger, and D. Nanongkai, “A deterministic almost-tight
    distributed algorithm for approximating single-source shortest paths,” in <i>48th
    Annual ACM SIGACT Symposium on Theory of Computing</i>, Cambridge, MA, United
    States, 2016, pp. 489–498.
  ista: 'Henzinger MH, Krinninger S, Nanongkai D. 2016. A deterministic almost-tight
    distributed algorithm for approximating single-source shortest paths. 48th Annual
    ACM SIGACT Symposium on Theory of Computing. STOC: Symposium on Theory of Computing,
    489–498.'
  mla: Henzinger, Monika H., et al. “A Deterministic Almost-Tight Distributed Algorithm
    for Approximating Single-Source Shortest Paths.” <i>48th Annual ACM SIGACT Symposium
    on Theory of Computing</i>, Association for Computing Machinery, 2016, pp. 489–98,
    doi:<a href="https://doi.org/10.1145/2897518.2897638">10.1145/2897518.2897638</a>.
  short: M.H. Henzinger, S. Krinninger, D. Nanongkai, in:, 48th Annual ACM SIGACT
    Symposium on Theory of Computing, Association for Computing Machinery, 2016, pp.
    489–498.
conference:
  end_date: 2016-06-21
  location: Cambridge, MA, United States
  name: 'STOC: Symposium on Theory of Computing'
  start_date: 2016-06-19
date_created: 2022-08-16T09:19:31Z
date_published: 2016-06-01T00:00:00Z
date_updated: 2023-02-17T10:32:23Z
day: '01'
doi: 10.1145/2897518.2897638
extern: '1'
external_id:
  arxiv:
  - '1504.07056'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1504.07056
month: '06'
oa: 1
oa_version: Preprint
page: 489 - 498
publication: 48th Annual ACM SIGACT Symposium on Theory of Computing
publication_identifier:
  isbn:
  - 978-145034132-5
  issn:
  - 0737-8017
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: A deterministic almost-tight distributed algorithm for approximating single-source
  shortest paths
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '11867'
abstract:
- lang: eng
  text: We present two deterministic dynamic algorithms for the maximum matching problem.
    (1) An algorithm that maintains a (2+є)-approximate maximum matching in general
    graphs with O(poly(logn, 1/є)) update time. (2) An algorithm that maintains an
    αK approximation of the value of the maximum matching with O(n2/K) update time
    in bipartite graphs, for every sufficiently large constant positive integer K.
    Here, 1≤ αK < 2 is a constant determined by the value of K. Result (1) is the
    first deterministic algorithm that can maintain an o(logn)-approximate maximum
    matching with polylogarithmic update time, improving the seminal result of Onak
    et al. [STOC 2010]. Its approximation guarantee almost matches the guarantee of
    the best randomized polylogarithmic update time algorithm [Baswana et al. FOCS
    2011]. Result (2) achieves a better-than-two approximation with arbitrarily small
    polynomial update time on bipartite graphs. Previously the best update time for
    this problem was O(m1/4) [Bernstein et al. ICALP 2015], where m is the current
    number of edges in the graph.
article_processing_charge: No
arxiv: 1
author:
- first_name: Sayan
  full_name: Bhattacharya, Sayan
  last_name: Bhattacharya
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Danupon
  full_name: Nanongkai, Danupon
  last_name: Nanongkai
citation:
  ama: 'Bhattacharya S, Henzinger MH, Nanongkai D. New deterministic approximation
    algorithms for fully dynamic matching. In: <i>48th Annual ACM SIGACT Symposium
    on Theory of Computing</i>. Association for Computing Machinery; 2016:398-411.
    doi:<a href="https://doi.org/10.1145/2897518.2897568">10.1145/2897518.2897568</a>'
  apa: 'Bhattacharya, S., Henzinger, M. H., &#38; Nanongkai, D. (2016). New deterministic
    approximation algorithms for fully dynamic matching. In <i>48th Annual ACM SIGACT
    Symposium on Theory of Computing</i> (pp. 398–411). Cambridge, MA, United States:
    Association for Computing Machinery. <a href="https://doi.org/10.1145/2897518.2897568">https://doi.org/10.1145/2897518.2897568</a>'
  chicago: Bhattacharya, Sayan, Monika H Henzinger, and Danupon Nanongkai. “New Deterministic
    Approximation Algorithms for Fully Dynamic Matching.” In <i>48th Annual ACM SIGACT
    Symposium on Theory of Computing</i>, 398–411. Association for Computing Machinery,
    2016. <a href="https://doi.org/10.1145/2897518.2897568">https://doi.org/10.1145/2897518.2897568</a>.
  ieee: S. Bhattacharya, M. H. Henzinger, and D. Nanongkai, “New deterministic approximation
    algorithms for fully dynamic matching,” in <i>48th Annual ACM SIGACT Symposium
    on Theory of Computing</i>, Cambridge, MA, United States, 2016, pp. 398–411.
  ista: 'Bhattacharya S, Henzinger MH, Nanongkai D. 2016. New deterministic approximation
    algorithms for fully dynamic matching. 48th Annual ACM SIGACT Symposium on Theory
    of Computing. STOC: Symposium on Theory of Computing, 398–411.'
  mla: Bhattacharya, Sayan, et al. “New Deterministic Approximation Algorithms for
    Fully Dynamic Matching.” <i>48th Annual ACM SIGACT Symposium on Theory of Computing</i>,
    Association for Computing Machinery, 2016, pp. 398–411, doi:<a href="https://doi.org/10.1145/2897518.2897568">10.1145/2897518.2897568</a>.
  short: S. Bhattacharya, M.H. Henzinger, D. Nanongkai, in:, 48th Annual ACM SIGACT
    Symposium on Theory of Computing, Association for Computing Machinery, 2016, pp.
    398–411.
conference:
  end_date: 2016-06-21
  location: Cambridge, MA, United States
  name: 'STOC: Symposium on Theory of Computing'
  start_date: 2016-06-19
date_created: 2022-08-16T09:27:35Z
date_published: 2016-06-01T00:00:00Z
date_updated: 2023-02-17T11:08:19Z
day: '01'
doi: 10.1145/2897518.2897568
extern: '1'
external_id:
  arxiv:
  - '1604.05765'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1604.05765
month: '06'
oa: 1
oa_version: Preprint
page: 398 - 411
publication: 48th Annual ACM SIGACT Symposium on Theory of Computing
publication_identifier:
  isbn:
  - 978-145034132-5
  issn:
  - 0737-8017
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: New deterministic approximation algorithms for fully dynamic matching
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '1188'
abstract:
- lang: eng
  text: "We consider a population dynamics model coupling cell growth to a diffusion
    in the space of metabolic phenotypes as it can be obtained from realistic constraints-based
    modelling. \r\nIn the asymptotic regime of slow\r\ndiffusion, that coincides with
    the relevant experimental range, the resulting\r\nnon-linear Fokker–Planck equation
    is solved for the steady state in the WKB\r\napproximation that maps it into the
    ground state of a quantum particle in an\r\nAiry potential plus a centrifugal
    term. We retrieve scaling laws for growth rate\r\nfluctuations and time response
    with respect to the distance from the maximum\r\ngrowth rate suggesting that suboptimal
    populations can have a faster response\r\nto perturbations."
acknowledgement: D De Martino is supported by the People Programme (Marie Curie Actions)
  of the European Union's Seventh Framework Programme (FP7/2007–2013) under REA grant
  agreement no. [291734]. D Masoero is supported by the FCT scholarship, number SFRH/BPD/75908/2011.
  D De Martino thanks the Grupo de Física Matemática of the Universidade de Lisboa
  for the kind hospitality. We also wish to thank Matteo Osella, Vincenzo Vitagliano
  and Vera Luz Masoero for useful discussions, also late at night.
article_number: '123502'
author:
- first_name: Daniele
  full_name: De Martino, Daniele
  id: 3FF5848A-F248-11E8-B48F-1D18A9856A87
  last_name: De Martino
  orcid: 0000-0002-5214-4706
- first_name: Davide
  full_name: Masoero, Davide
  last_name: Masoero
citation:
  ama: 'De Martino D, Masoero D. Asymptotic analysis of noisy fitness maximization,
    applied to metabolism &#38;amp; growth. <i> Journal of Statistical Mechanics:
    Theory and Experiment</i>. 2016;2016(12). doi:<a href="https://doi.org/10.1088/1742-5468/aa4e8f">10.1088/1742-5468/aa4e8f</a>'
  apa: 'De Martino, D., &#38; Masoero, D. (2016). Asymptotic analysis of noisy fitness
    maximization, applied to metabolism &#38;amp; growth. <i> Journal of Statistical
    Mechanics: Theory and Experiment</i>. IOPscience. <a href="https://doi.org/10.1088/1742-5468/aa4e8f">https://doi.org/10.1088/1742-5468/aa4e8f</a>'
  chicago: 'De Martino, Daniele, and Davide Masoero. “Asymptotic Analysis of Noisy
    Fitness Maximization, Applied to Metabolism &#38;amp; Growth.” <i> Journal of
    Statistical Mechanics: Theory and Experiment</i>. IOPscience, 2016. <a href="https://doi.org/10.1088/1742-5468/aa4e8f">https://doi.org/10.1088/1742-5468/aa4e8f</a>.'
  ieee: 'D. De Martino and D. Masoero, “Asymptotic analysis of noisy fitness maximization,
    applied to metabolism &#38;amp; growth,” <i> Journal of Statistical Mechanics:
    Theory and Experiment</i>, vol. 2016, no. 12. IOPscience, 2016.'
  ista: 'De Martino D, Masoero D. 2016. Asymptotic analysis of noisy fitness maximization,
    applied to metabolism &#38;amp; growth.  Journal of Statistical Mechanics: Theory
    and Experiment. 2016(12), 123502.'
  mla: 'De Martino, Daniele, and Davide Masoero. “Asymptotic Analysis of Noisy Fitness
    Maximization, Applied to Metabolism &#38;amp; Growth.” <i> Journal of Statistical
    Mechanics: Theory and Experiment</i>, vol. 2016, no. 12, 123502, IOPscience, 2016,
    doi:<a href="https://doi.org/10.1088/1742-5468/aa4e8f">10.1088/1742-5468/aa4e8f</a>.'
  short: 'D. De Martino, D. Masoero,  Journal of Statistical Mechanics: Theory and
    Experiment 2016 (2016).'
date_created: 2018-12-11T11:50:37Z
date_published: 2016-12-30T00:00:00Z
date_updated: 2021-01-12T06:48:57Z
day: '30'
department:
- _id: GaTk
doi: 10.1088/1742-5468/aa4e8f
ec_funded: 1
intvolume: '      2016'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1606.09048
month: '12'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: ' Journal of Statistical Mechanics: Theory and Experiment'
publication_status: published
publisher: IOPscience
publist_id: '6165'
quality_controlled: '1'
scopus_import: 1
status: public
title: Asymptotic analysis of noisy fitness maximization, applied to metabolism &amp;
  growth
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2016
year: '2016'
...
---
_id: '1189'
abstract:
- lang: eng
  text: "Within the scope of this thesis,  we show that a driven-dissipative system
    with\r\nfew ultracold atoms can exhibit dissipatively bound states, even if the
    atom-atom\r\ninteraction is purely repulsive.  This bond arises due to the dipole-dipole
    inter-\r\naction, which is restricted to one of the lower electronic energy states,
    resulting\r\nin the distance-dependent coherent population trapping.  The quality
    of this al-\r\nready established method of dissipative binding is improved and
    the application\r\nis extended to higher dimensions and a larger number of atoms.
    \ Here, we simu-\r\nlate two- and three-atom systems using an adapted approach
    to the Monte Carlo\r\nwave-function  method  and  analyse  the  results.   Finally,
    \ we  examine  the  possi-\r\nbility  of  finding  a  setting  allowing  trimer
    \ states  but  prohibiting  dimer  states.\r\nIn the context of open quantum systems,
    such a three-body bound states corre-\r\nsponds to the driven-dissipative analogue
    of a Borromean state.  These states can\r\nbe detected in modern experiments with
    dipolar and Rydberg-dressed ultracold\r\natomic gases.\r\n"
article_processing_charge: No
author:
- first_name: Clemens
  full_name: Jochum, Clemens
  last_name: Jochum
citation:
  ama: Jochum C. Dissipative Few-Body Quantum Systems. 2016.
  apa: Jochum, C. (2016). <i>Dissipative Few-Body Quantum Systems</i>. Technical University
    Vienna.
  chicago: Jochum, Clemens. “Dissipative Few-Body Quantum Systems.” Technical University
    Vienna, 2016.
  ieee: C. Jochum, “Dissipative Few-Body Quantum Systems,” Technical University Vienna,
    2016.
  ista: Jochum C. 2016. Dissipative Few-Body Quantum Systems. Technical University
    Vienna.
  mla: Jochum, Clemens. <i>Dissipative Few-Body Quantum Systems</i>. Technical University
    Vienna, 2016.
  short: C. Jochum, Dissipative Few-Body Quantum Systems, Technical University Vienna,
    2016.
date_created: 2018-12-11T11:50:37Z
date_published: 2016-11-28T00:00:00Z
date_updated: 2021-01-12T06:48:57Z
day: '28'
extern: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://repositum.tuwien.ac.at/obvutwhs/content/titleinfo/1517088
month: '11'
oa: 1
oa_version: Published Version
page: '94'
publication_status: published
publisher: Technical University Vienna
publist_id: '6164'
status: public
supervisor:
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: Peter
  full_name: Rabl, Peter
  last_name: Rabl
title: Dissipative Few-Body Quantum Systems
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '11891'
abstract:
- lang: eng
  text: "We study dynamic (1+\U0001D716)-approximation algorithms for the all-pairs
    shortest paths problem in unweighted undirected \U0001D45B-node \U0001D45A-edge
    graphs under edge deletions. The fastest algorithm for this problem is a randomized
    algorithm with a total update time of \U0001D442̃ (\U0001D45A\U0001D45B/\U0001D716)
    and constant query time by Roditty and Zwick [SIAM J. Comput., 41 (2012), pp.
    670--683]. The fastest deterministic algorithm is from a 1981 paper by Even and
    Shiloach [J. ACM, 28 (1981), pp. 1--4]; it has a total update time of \U0001D442(\U0001D45A\U0001D45B2)
    and constant query time. We improve these results as follows: (1) We present an
    algorithm with a total update time of \U0001D442̃ (\U0001D45B5/2/\U0001D716) and
    constant query time that has an additive error of 2 in addition to the 1+\U0001D716
    multiplicative error. This beats the previous \U0001D442̃ (\U0001D45A\U0001D45B/\U0001D716)
    time when \U0001D45A=Ω(\U0001D45B3/2). Note that the additive error is unavoidable
    since, even in the static case, an \U0001D442(\U0001D45B3−\U0001D6FF)-time (a
    so-called truly subcubic) combinatorial algorithm with 1+\U0001D716 multiplicative
    error cannot have an additive error less than 2−\U0001D716, unless we make a major
    breakthrough for Boolean matrix multiplication [D. Dor, S. Halrepin, and U. Zwick,
    SIAM J. Comput., 29 (2000), pp. 1740--1759] and many other long-standing problems
    [V. Vassilevska Williams and R. Williams, Proceedings of the 2010 IEEE 51st Annual
    Symposium on Foundations of Computer Science, 2010, pp. 645--654]. The algorithm
    can also be turned into a (2+\U0001D716)-approximation algorithm (without an additive
    error) with the same time guarantees, improving the recent (3+\U0001D716)-approximation
    algorithm with \U0001D442̃ (\U0001D45B5/2+\U0001D442(log(1/\U0001D716)/log\U0001D45B√))
    running time of Bernstein and Roditty [Proceedings of the Twenty-Second Annual
    ACM-SIAM Symposium on Discrete Algorithms, 2011, pp. 1355--1365] in terms of both
    approximation and time guarantees. (2) We present a deterministic algorithm with
    a total update time of \U0001D442̃ (\U0001D45A\U0001D45B/\U0001D716) and a query
    time of \U0001D442(loglog\U0001D45B). The algorithm has a multiplicative error
    of 1+\U0001D716 and gives the first improved deterministic algorithm since 1981.
    It also answers an open question raised by Bernstein in [Proceedings of the Forty-Fifth
    Annual ACM Symposium on Theory of Computing, 2013, pp. 725--734]. The deterministic
    algorithm can be turned into a deterministic fully dynamic (1+\U0001D716)-approximation
    with an amortized update time of \U0001D442̃ (\U0001D45A\U0001D45B/(\U0001D716\U0001D461))
    and a query time of \U0001D442̃ (\U0001D461) for every \U0001D461≤\U0001D45B√.
    In order to achieve our results, we introduce two new techniques: (i) A monotone
    Even--Shiloach tree algorithm which maintains a bounded-distance shortest-paths
    tree on a certain type of emulator called a locally persevering emulator. (ii)
    A derandomization technique based on moving Even--Shiloach trees as a way to derandomize
    the standard random set argument. These techniques might be of independent interest."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Sebastian
  full_name: Krinninger, Sebastian
  last_name: Krinninger
- first_name: Danupon
  full_name: Nanongkai, Danupon
  last_name: Nanongkai
citation:
  ama: 'Henzinger MH, Krinninger S, Nanongkai D. Dynamic approximate all-pairs shortest
    paths: Breaking the O(mn) barrier and derandomization. <i>SIAM Journal on Computing</i>.
    2016;45(3):947-1006. doi:<a href="https://doi.org/10.1137/140957299">10.1137/140957299</a>'
  apa: 'Henzinger, M. H., Krinninger, S., &#38; Nanongkai, D. (2016). Dynamic approximate
    all-pairs shortest paths: Breaking the O(mn) barrier and derandomization. <i>SIAM
    Journal on Computing</i>. Society for Industrial &#38; Applied Mathematics. <a
    href="https://doi.org/10.1137/140957299">https://doi.org/10.1137/140957299</a>'
  chicago: 'Henzinger, Monika H, Sebastian Krinninger, and Danupon Nanongkai. “Dynamic
    Approximate All-Pairs Shortest Paths: Breaking the O(Mn) Barrier and Derandomization.”
    <i>SIAM Journal on Computing</i>. Society for Industrial &#38; Applied Mathematics,
    2016. <a href="https://doi.org/10.1137/140957299">https://doi.org/10.1137/140957299</a>.'
  ieee: 'M. H. Henzinger, S. Krinninger, and D. Nanongkai, “Dynamic approximate all-pairs
    shortest paths: Breaking the O(mn) barrier and derandomization,” <i>SIAM Journal
    on Computing</i>, vol. 45, no. 3. Society for Industrial &#38; Applied Mathematics,
    pp. 947–1006, 2016.'
  ista: 'Henzinger MH, Krinninger S, Nanongkai D. 2016. Dynamic approximate all-pairs
    shortest paths: Breaking the O(mn) barrier and derandomization. SIAM Journal on
    Computing. 45(3), 947–1006.'
  mla: 'Henzinger, Monika H., et al. “Dynamic Approximate All-Pairs Shortest Paths:
    Breaking the O(Mn) Barrier and Derandomization.” <i>SIAM Journal on Computing</i>,
    vol. 45, no. 3, Society for Industrial &#38; Applied Mathematics, 2016, pp. 947–1006,
    doi:<a href="https://doi.org/10.1137/140957299">10.1137/140957299</a>.'
  short: M.H. Henzinger, S. Krinninger, D. Nanongkai, SIAM Journal on Computing 45
    (2016) 947–1006.
date_created: 2022-08-17T08:37:00Z
date_published: 2016-05-01T00:00:00Z
date_updated: 2023-02-17T14:21:40Z
day: '01'
doi: 10.1137/140957299
extern: '1'
external_id:
  arxiv:
  - '1308.0776'
intvolume: '        45'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1308.0776
month: '05'
oa: 1
oa_version: Preprint
page: 947-1006
publication: SIAM Journal on Computing
publication_identifier:
  eissn:
  - 1095-7111
  issn:
  - 0097-5397
publication_status: published
publisher: Society for Industrial & Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Dynamic approximate all-pairs shortest paths: Breaking the O(mn) barrier and
  derandomization'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 45
year: '2016'
...
---
_id: '1193'
abstract:
- lang: eng
  text: We consider the recent formulation of the Algorithmic Lovász Local Lemma [1],
    [2] for finding objects that avoid &quot;bad features&quot;, or &quot;flaws&quot;.
    It extends the Moser-Tardos resampling algorithm [3] to more general discrete
    spaces. At each step the method picks a flaw present in the current state and
    &quot;resamples&quot; it using a &quot;resampling oracle&quot; provided by the
    user. However, it is less flexible than the Moser-Tardos method since [1], [2]
    require a specific flaw selection rule, whereas [3] allows an arbitrary rule (and
    thus can potentially be implemented more efficiently). We formulate a new &quot;commutativity&quot;
    condition, and prove that it is sufficient for an arbitrary rule to work. It also
    enables an efficient parallelization under an additional assumption. We then show
    that existing resampling oracles for perfect matchings and permutations do satisfy
    this condition. Finally, we generalize the precondition in [2] (in the case of
    symmetric potential causality graphs). This unifies special cases that previously
    were treated separately.
acknowledgement: European Unions Seventh Framework Programme (FP7/2007-2013)/ERC grant
  agreement no 616160
article_number: '7782993'
article_processing_charge: No
arxiv: 1
author:
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
citation:
  ama: 'Kolmogorov V. Commutativity in the algorithmic Lovasz local lemma. In: <i>Proceedings
    - Annual IEEE Symposium on Foundations of Computer Science</i>. Vol 2016-December.
    IEEE; 2016. doi:<a href="https://doi.org/10.1109/FOCS.2016.88">10.1109/FOCS.2016.88</a>'
  apa: 'Kolmogorov, V. (2016). Commutativity in the algorithmic Lovasz local lemma.
    In <i>Proceedings - Annual IEEE Symposium on Foundations of Computer Science</i>
    (Vol. 2016–December). New Brunswick, NJ, USA : IEEE. <a href="https://doi.org/10.1109/FOCS.2016.88">https://doi.org/10.1109/FOCS.2016.88</a>'
  chicago: Kolmogorov, Vladimir. “Commutativity in the Algorithmic Lovasz Local Lemma.”
    In <i>Proceedings - Annual IEEE Symposium on Foundations of Computer Science</i>,
    Vol. 2016–December. IEEE, 2016. <a href="https://doi.org/10.1109/FOCS.2016.88">https://doi.org/10.1109/FOCS.2016.88</a>.
  ieee: V. Kolmogorov, “Commutativity in the algorithmic Lovasz local lemma,” in <i>Proceedings
    - Annual IEEE Symposium on Foundations of Computer Science</i>, New Brunswick,
    NJ, USA , 2016, vol. 2016–December.
  ista: 'Kolmogorov V. 2016. Commutativity in the algorithmic Lovasz local lemma.
    Proceedings - Annual IEEE Symposium on Foundations of Computer Science. FOCS:
    Foundations of Computer Science vol. 2016–December, 7782993.'
  mla: Kolmogorov, Vladimir. “Commutativity in the Algorithmic Lovasz Local Lemma.”
    <i>Proceedings - Annual IEEE Symposium on Foundations of Computer Science</i>,
    vol. 2016–December, 7782993, IEEE, 2016, doi:<a href="https://doi.org/10.1109/FOCS.2016.88">10.1109/FOCS.2016.88</a>.
  short: V. Kolmogorov, in:, Proceedings - Annual IEEE Symposium on Foundations of
    Computer Science, IEEE, 2016.
conference:
  end_date: 2016-09-11
  location: 'New Brunswick, NJ, USA '
  name: 'FOCS: Foundations of Computer Science'
  start_date: 2016-09-09
date_created: 2018-12-11T11:50:38Z
date_published: 2016-12-15T00:00:00Z
date_updated: 2023-09-19T14:24:57Z
day: '15'
department:
- _id: VlKo
doi: 10.1109/FOCS.2016.88
ec_funded: 1
external_id:
  arxiv:
  - '1506.08547'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1506.08547v7
month: '12'
oa: 1
oa_version: Preprint
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '616160'
  name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: Proceedings - Annual IEEE Symposium on Foundations of Computer Science
publication_status: published
publisher: IEEE
publist_id: '6158'
quality_controlled: '1'
related_material:
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scopus_import: 1
status: public
title: Commutativity in the algorithmic Lovasz local lemma
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2016-December
year: '2016'
...
---
_id: '1195'
abstract:
- lang: eng
  text: 'The genetic analysis of experimentally evolving populations typically relies
    on short reads from pooled individuals (Pool-Seq). While this method provides
    reliable allele frequency estimates, the underlying haplotype structure remains
    poorly characterized. With small population sizes and adaptive variants that start
    from low frequencies, the interpretation of selection signatures in most Evolve
    and Resequencing studies remains challenging. To facilitate the characterization
    of selection targets, we propose a new approach that reconstructs selected haplotypes
    from replicated time series, using Pool-Seq data. We identify selected haplotypes
    through the correlated frequencies of alleles carried by them. Computer simulations
    indicate that selected haplotype-blocks of several Mb can be reconstructed with
    high confidence and low error rates, even when allele frequencies change only
    by 20% across three replicates. Applying this method to real data from D. melanogaster
    populations adapting to a hot environment, we identify a selected haplotype-block
    of 6.93 Mb. We confirm the presence of this haplotype-block in evolved populations
    by experimental haplotyping, demonstrating the power and accuracy of our haplotype
    reconstruction from Pool-Seq data. We propose that the combination of allele frequency
    estimates with haplotype information will provide the key to understanding the
    dynamics of adaptive alleles. '
acknowledgement: "The authors thank all members of the Institute of Population\r\nGenetics
  for discussion and support on the project and par-\r\nticularly N. Barghi for helpful
  comments on earlier versions of\r\nthe  manuscript.  This  work  was  supported
  \ by  the  European\r\nResearch Council (ERC) grants “ArchAdapt” and “250152”."
author:
- first_name: Susan
  full_name: Franssen, Susan
  last_name: Franssen
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Christian
  full_name: Schlötterer, Christian
  last_name: Schlötterer
citation:
  ama: Franssen S, Barton NH, Schlötterer C. Reconstruction of haplotype-blocks selected
    during experimental evolution. <i>Molecular Biology and Evolution</i>. 2016;34(1):174-184.
    doi:<a href="https://doi.org/10.1093/molbev/msw210">10.1093/molbev/msw210</a>
  apa: Franssen, S., Barton, N. H., &#38; Schlötterer, C. (2016). Reconstruction of
    haplotype-blocks selected during experimental evolution. <i>Molecular Biology
    and Evolution</i>. Oxford University Press. <a href="https://doi.org/10.1093/molbev/msw210">https://doi.org/10.1093/molbev/msw210</a>
  chicago: Franssen, Susan, Nicholas H Barton, and Christian Schlötterer. “Reconstruction
    of Haplotype-Blocks Selected during Experimental Evolution.” <i>Molecular Biology
    and Evolution</i>. Oxford University Press, 2016. <a href="https://doi.org/10.1093/molbev/msw210">https://doi.org/10.1093/molbev/msw210</a>.
  ieee: S. Franssen, N. H. Barton, and C. Schlötterer, “Reconstruction of haplotype-blocks
    selected during experimental evolution.,” <i>Molecular Biology and Evolution</i>,
    vol. 34, no. 1. Oxford University Press, pp. 174–184, 2016.
  ista: Franssen S, Barton NH, Schlötterer C. 2016. Reconstruction of haplotype-blocks
    selected during experimental evolution. Molecular Biology and Evolution. 34(1),
    174–184.
  mla: Franssen, Susan, et al. “Reconstruction of Haplotype-Blocks Selected during
    Experimental Evolution.” <i>Molecular Biology and Evolution</i>, vol. 34, no.
    1, Oxford University Press, 2016, pp. 174–84, doi:<a href="https://doi.org/10.1093/molbev/msw210">10.1093/molbev/msw210</a>.
  short: S. Franssen, N.H. Barton, C. Schlötterer, Molecular Biology and Evolution
    34 (2016) 174–184.
date_created: 2018-12-11T11:50:39Z
date_published: 2016-10-03T00:00:00Z
date_updated: 2021-01-12T06:49:00Z
day: '03'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1093/molbev/msw210
ec_funded: 1
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has_accepted_license: '1'
intvolume: '        34'
issue: '1'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Submitted Version
page: 174 - 184
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
publication: Molecular Biology and Evolution
publication_status: published
publisher: Oxford University Press
publist_id: '6155'
pubrep_id: '770'
quality_controlled: '1'
scopus_import: 1
status: public
title: Reconstruction of haplotype-blocks selected during experimental evolution.
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2016'
...
---
_id: '1197'
abstract:
- lang: eng
  text: Across the nervous system, certain population spiking patterns are observed
    far more frequently than others. A hypothesis about this structure is that these
    collective activity patterns function as population codewords–collective modes–carrying
    information distinct from that of any single cell. We investigate this phenomenon
    in recordings of ∼150 retinal ganglion cells, the retina’s output. We develop
    a novel statistical model that decomposes the population response into modes;
    it predicts the distribution of spiking activity in the ganglion cell population
    with high accuracy. We found that the modes represent localized features of the
    visual stimulus that are distinct from the features represented by single neurons.
    Modes form clusters of activity states that are readily discriminated from one
    another. When we repeated the same visual stimulus, we found that the same mode
    was robustly elicited. These results suggest that retinal ganglion cells’ collective
    signaling is endowed with a form of error-correcting code–a principle that may
    hold in brain areas beyond retina.
acknowledgement: JSP was supported by a C.V. Starr Fellowship from the Starr Foundation
  (http://www.starrfoundation.org/). GT was supported by Austrian Research Foundation
  (https://www.fwf.ac.at/en/) grant FWF P25651. MJB received support from National
  Eye Institute (https://nei.nih.gov/) grant EY 14196 and from the National Science
  Foundation grant 1504977. The authors thank Cristina Savin and Vicent Botella-Soler
  for helpful comments on the manuscript.
article_number: e1005855
author:
- first_name: Jason
  full_name: Prentice, Jason
  last_name: Prentice
- first_name: Olivier
  full_name: Marre, Olivier
  last_name: Marre
- first_name: Mark
  full_name: Ioffe, Mark
  last_name: Ioffe
- first_name: Adrianna
  full_name: Loback, Adrianna
  last_name: Loback
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
- first_name: Michael
  full_name: Berry, Michael
  last_name: Berry
citation:
  ama: Prentice J, Marre O, Ioffe M, Loback A, Tkačik G, Berry M. Error-robust modes
    of the retinal population code. <i>PLoS Computational Biology</i>. 2016;12(11).
    doi:<a href="https://doi.org/10.1371/journal.pcbi.1005148">10.1371/journal.pcbi.1005148</a>
  apa: Prentice, J., Marre, O., Ioffe, M., Loback, A., Tkačik, G., &#38; Berry, M.
    (2016). Error-robust modes of the retinal population code. <i>PLoS Computational
    Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1005148">https://doi.org/10.1371/journal.pcbi.1005148</a>
  chicago: Prentice, Jason, Olivier Marre, Mark Ioffe, Adrianna Loback, Gašper Tkačik,
    and Michael Berry. “Error-Robust Modes of the Retinal Population Code.” <i>PLoS
    Computational Biology</i>. Public Library of Science, 2016. <a href="https://doi.org/10.1371/journal.pcbi.1005148">https://doi.org/10.1371/journal.pcbi.1005148</a>.
  ieee: J. Prentice, O. Marre, M. Ioffe, A. Loback, G. Tkačik, and M. Berry, “Error-robust
    modes of the retinal population code,” <i>PLoS Computational Biology</i>, vol.
    12, no. 11. Public Library of Science, 2016.
  ista: Prentice J, Marre O, Ioffe M, Loback A, Tkačik G, Berry M. 2016. Error-robust
    modes of the retinal population code. PLoS Computational Biology. 12(11), e1005855.
  mla: Prentice, Jason, et al. “Error-Robust Modes of the Retinal Population Code.”
    <i>PLoS Computational Biology</i>, vol. 12, no. 11, e1005855, Public Library of
    Science, 2016, doi:<a href="https://doi.org/10.1371/journal.pcbi.1005148">10.1371/journal.pcbi.1005148</a>.
  short: J. Prentice, O. Marre, M. Ioffe, A. Loback, G. Tkačik, M. Berry, PLoS Computational
    Biology 12 (2016).
date_created: 2018-12-11T11:50:40Z
date_published: 2016-11-17T00:00:00Z
date_updated: 2023-02-23T14:05:40Z
day: '17'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1005148
file:
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  checksum: 47b08cbd4dbf32b25ba161f5f4b262cc
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  creator: kschuh
  date_created: 2019-01-25T10:35:00Z
  date_updated: 2020-07-14T12:44:38Z
  file_id: '5884'
  file_name: 2016_PLOS_Prentice.pdf
  file_size: 4492021
  relation: main_file
file_date_updated: 2020-07-14T12:44:38Z
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- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 254D1A94-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 25651-N26
  name: Sensitivity to higher-order statistics in natural scenes
publication: PLoS Computational Biology
publication_status: published
publisher: Public Library of Science
publist_id: '6153'
quality_controlled: '1'
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title: Error-robust modes of the retinal population code
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2016'
...
---
_id: '1200'
acknowledgement: C.H. acknowledges generous support from the ISTFELLOW program.
author:
- first_name: Christian
  full_name: Hilbe, Christian
  id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
  last_name: Hilbe
  orcid: 0000-0001-5116-955X
- first_name: Arne
  full_name: Traulsen, Arne
  last_name: Traulsen
citation:
  ama: 'Hilbe C, Traulsen A. Only the combination of mathematics and agent based simulations
    can leverage the full potential of evolutionary modeling: Comment on “Evolutionary
    game theory using agent-based methods” by C. Adami, J. Schossau and A. Hintze.
    <i>Physics of Life Reviews</i>. 2016;19:29-31. doi:<a href="https://doi.org/10.1016/j.plrev.2016.10.004">10.1016/j.plrev.2016.10.004</a>'
  apa: 'Hilbe, C., &#38; Traulsen, A. (2016). Only the combination of mathematics
    and agent based simulations can leverage the full potential of evolutionary modeling:
    Comment on “Evolutionary game theory using agent-based methods” by C. Adami, J.
    Schossau and A. Hintze. <i>Physics of Life Reviews</i>. Elsevier. <a href="https://doi.org/10.1016/j.plrev.2016.10.004">https://doi.org/10.1016/j.plrev.2016.10.004</a>'
  chicago: 'Hilbe, Christian, and Arne Traulsen. “Only the Combination of Mathematics
    and Agent Based Simulations Can Leverage the Full Potential of Evolutionary Modeling:
    Comment on ‘Evolutionary Game Theory Using Agent-Based Methods’ by C. Adami, J.
    Schossau and A. Hintze.” <i>Physics of Life Reviews</i>. Elsevier, 2016. <a href="https://doi.org/10.1016/j.plrev.2016.10.004">https://doi.org/10.1016/j.plrev.2016.10.004</a>.'
  ieee: 'C. Hilbe and A. Traulsen, “Only the combination of mathematics and agent
    based simulations can leverage the full potential of evolutionary modeling: Comment
    on ‘Evolutionary game theory using agent-based methods’ by C. Adami, J. Schossau
    and A. Hintze,” <i>Physics of Life Reviews</i>, vol. 19. Elsevier, pp. 29–31,
    2016.'
  ista: 'Hilbe C, Traulsen A. 2016. Only the combination of mathematics and agent
    based simulations can leverage the full potential of evolutionary modeling: Comment
    on “Evolutionary game theory using agent-based methods” by C. Adami, J. Schossau
    and A. Hintze. Physics of Life Reviews. 19, 29–31.'
  mla: 'Hilbe, Christian, and Arne Traulsen. “Only the Combination of Mathematics
    and Agent Based Simulations Can Leverage the Full Potential of Evolutionary Modeling:
    Comment on ‘Evolutionary Game Theory Using Agent-Based Methods’ by C. Adami, J.
    Schossau and A. Hintze.” <i>Physics of Life Reviews</i>, vol. 19, Elsevier, 2016,
    pp. 29–31, doi:<a href="https://doi.org/10.1016/j.plrev.2016.10.004">10.1016/j.plrev.2016.10.004</a>.'
  short: C. Hilbe, A. Traulsen, Physics of Life Reviews 19 (2016) 29–31.
date_created: 2018-12-11T11:50:40Z
date_published: 2016-12-01T00:00:00Z
date_updated: 2021-01-12T06:49:03Z
day: '01'
ddc:
- '530'
department:
- _id: KrCh
doi: 10.1016/j.plrev.2016.10.004
ec_funded: 1
file:
- access_level: open_access
  checksum: 95e6dc78278334b99dacbf8822509364
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  creator: system
  date_created: 2018-12-12T10:11:02Z
  date_updated: 2020-07-14T12:44:39Z
  file_id: '4855'
  file_name: IST-2017-798-v1+1_comment_adami.pdf
  file_size: 171352
  relation: main_file
file_date_updated: 2020-07-14T12:44:39Z
has_accepted_license: '1'
intvolume: '        19'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '12'
oa: 1
oa_version: Submitted Version
page: 29 - 31
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Physics of Life Reviews
publication_status: published
publisher: Elsevier
publist_id: '6150'
pubrep_id: '798'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Only the combination of mathematics and agent based simulations can leverage
  the full potential of evolutionary modeling: Comment on “Evolutionary game theory
  using agent-based methods” by C. Adami, J. Schossau and A. Hintze'
tmp:
  image: /images/cc_by_nc_nd.png
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  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2016'
...
---
_id: '1202'
acknowledgement: The authors thank Sophie A.O. Armitage and Jan N. Offenborn for helpful
  comments on the figures, and two anonymous reviewers for their helpful comments.
  The project was funded by the Deutsche Forschungsgemeinschaft (DFG, KU 1929/4-2)
  within the priority programme SPP 1399 “Host–Parasite Coevolution”.
author:
- first_name: Barbara
  full_name: Milutinovic, Barbara
  id: 2CDC32B8-F248-11E8-B48F-1D18A9856A87
  last_name: Milutinovic
  orcid: 0000-0002-8214-4758
- first_name: Robert
  full_name: Peuß, Robert
  last_name: Peuß
- first_name: Kevin
  full_name: Ferro, Kevin
  last_name: Ferro
- first_name: Joachim
  full_name: Kurtz, Joachim
  last_name: Kurtz
citation:
  ama: 'Milutinovic B, Peuß R, Ferro K, Kurtz J. Immune priming in arthropods: an
    update focusing on the red flour beetle. <i>Zoology </i>. 2016;119(4):254-261.
    doi:<a href="https://doi.org/10.1016/j.zool.2016.03.006">10.1016/j.zool.2016.03.006</a>'
  apa: 'Milutinovic, B., Peuß, R., Ferro, K., &#38; Kurtz, J. (2016). Immune priming
    in arthropods: an update focusing on the red flour beetle. <i>Zoology </i>. Elsevier.
    <a href="https://doi.org/10.1016/j.zool.2016.03.006">https://doi.org/10.1016/j.zool.2016.03.006</a>'
  chicago: 'Milutinovic, Barbara, Robert Peuß, Kevin Ferro, and Joachim Kurtz. “Immune
    Priming in Arthropods: An Update Focusing on the Red Flour Beetle.” <i>Zoology
    </i>. Elsevier, 2016. <a href="https://doi.org/10.1016/j.zool.2016.03.006">https://doi.org/10.1016/j.zool.2016.03.006</a>.'
  ieee: 'B. Milutinovic, R. Peuß, K. Ferro, and J. Kurtz, “Immune priming in arthropods:
    an update focusing on the red flour beetle,” <i>Zoology </i>, vol. 119, no. 4.
    Elsevier, pp. 254–261, 2016.'
  ista: 'Milutinovic B, Peuß R, Ferro K, Kurtz J. 2016. Immune priming in arthropods:
    an update focusing on the red flour beetle. Zoology . 119(4), 254–261.'
  mla: 'Milutinovic, Barbara, et al. “Immune Priming in Arthropods: An Update Focusing
    on the Red Flour Beetle.” <i>Zoology </i>, vol. 119, no. 4, Elsevier, 2016, pp.
    254–61, doi:<a href="https://doi.org/10.1016/j.zool.2016.03.006">10.1016/j.zool.2016.03.006</a>.'
  short: B. Milutinovic, R. Peuß, K. Ferro, J. Kurtz, Zoology  119 (2016) 254–261.
date_created: 2018-12-11T11:50:41Z
date_published: 2016-08-01T00:00:00Z
date_updated: 2021-01-12T06:49:03Z
day: '01'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.1016/j.zool.2016.03.006
file:
- access_level: open_access
  checksum: 8396d5bd95f9c4295857162f902afabf
  content_type: application/pdf
  creator: kschuh
  date_created: 2019-01-25T13:00:20Z
  date_updated: 2020-07-14T12:44:39Z
  file_id: '5885'
  file_name: 2016_Elsevier_Milutinovic.pdf
  file_size: 1473211
  relation: main_file
file_date_updated: 2020-07-14T12:44:39Z
has_accepted_license: '1'
intvolume: '       119'
issue: '4'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 254 - 261
project:
- _id: 25DAF0B2-B435-11E9-9278-68D0E5697425
  grant_number: CR-118/3-1
  name: Host-Parasite Coevolution
publication: 'Zoology '
publication_status: published
publisher: Elsevier
publist_id: '6147'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Immune priming in arthropods: an update focusing on the red flour beetle'
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2016'
...
---
_id: '1203'
abstract:
- lang: eng
  text: Haemophilus haemolyticus has been recently discovered to have the potential
    to cause invasive disease. It is closely related to nontypeable Haemophilus influenzae
    (NT H. influenzae). NT H. influenzae and H. haemolyticus are often misidentified
    because none of the existing tests targeting the known phenotypes of H. haemolyticus
    are able to specifically identify H. haemolyticus. Through comparative genomic
    analysis of H. haemolyticus and NT H. influenzae, we identified genes unique to
    H. haemolyticus that can be used as targets for the identification of H. haemolyticus.
    A real-time PCR targeting purT (encoding phosphoribosylglycinamide formyltransferase
    2 in the purine synthesis pathway) was developed and evaluated. The lower limit
    of detection was 40 genomes/PCR; the sensitivity and specificity in detecting
    H. haemolyticus were 98.9% and 97%, respectively. To improve the discrimination
    of H. haemolyticus and NT H. influenzae, a testing scheme combining two targets
    (H. haemolyticus purT and H. influenzae hpd, encoding protein D lipoprotein) was
    also evaluated and showed 96.7% sensitivity and 98.2% specificity for the identification
    of H. haemolyticus and 92.8% sensitivity and 100% specificity for the identification
    of H. influenzae, respectively. The dual-target testing scheme can be used for
    the diagnosis and surveillance of infection and disease caused by H. haemolyticus
    and NT H. influenzae.
acknowledgement: We are grateful to ABCs for providing strains and the Bacterial Meningitis
  Laboratory for technical support.
author:
- first_name: Fang
  full_name: Hu, Fang
  last_name: Hu
- first_name: Lavanya
  full_name: Rishishwar, Lavanya
  last_name: Rishishwar
- first_name: Ambily
  full_name: Sivadas, Ambily
  last_name: Sivadas
- first_name: Gabriel
  full_name: Mitchell, Gabriel
  id: 315BCD80-F248-11E8-B48F-1D18A9856A87
  last_name: Mitchell
- first_name: Jordan
  full_name: King, Jordan
  last_name: King
- first_name: Timothy
  full_name: Murphy, Timothy
  last_name: Murphy
- first_name: Janet
  full_name: Gilsdorf, Janet
  last_name: Gilsdorf
- first_name: Leonard
  full_name: Mayer, Leonard
  last_name: Mayer
- first_name: Xin
  full_name: Wang, Xin
  last_name: Wang
citation:
  ama: Hu F, Rishishwar L, Sivadas A, et al. Comparative genomic analysis of Haemophilus
    haemolyticus and nontypeable Haemophilus influenzae and a new testing scheme for
    their discrimination. <i>Journal of Clinical Microbiology</i>. 2016;54(12):3010-3017.
    doi:<a href="https://doi.org/10.1128/JCM.01511-16">10.1128/JCM.01511-16</a>
  apa: Hu, F., Rishishwar, L., Sivadas, A., Mitchell, G., King, J., Murphy, T., …
    Wang, X. (2016). Comparative genomic analysis of Haemophilus haemolyticus and
    nontypeable Haemophilus influenzae and a new testing scheme for their discrimination.
    <i>Journal of Clinical Microbiology</i>. American Society for Microbiology. <a
    href="https://doi.org/10.1128/JCM.01511-16">https://doi.org/10.1128/JCM.01511-16</a>
  chicago: Hu, Fang, Lavanya Rishishwar, Ambily Sivadas, Gabriel Mitchell, Jordan
    King, Timothy Murphy, Janet Gilsdorf, Leonard Mayer, and Xin Wang. “Comparative
    Genomic Analysis of Haemophilus Haemolyticus and Nontypeable Haemophilus Influenzae
    and a New Testing Scheme for Their Discrimination.” <i>Journal of Clinical Microbiology</i>.
    American Society for Microbiology, 2016. <a href="https://doi.org/10.1128/JCM.01511-16">https://doi.org/10.1128/JCM.01511-16</a>.
  ieee: F. Hu <i>et al.</i>, “Comparative genomic analysis of Haemophilus haemolyticus
    and nontypeable Haemophilus influenzae and a new testing scheme for their discrimination,”
    <i>Journal of Clinical Microbiology</i>, vol. 54, no. 12. American Society for
    Microbiology, pp. 3010–3017, 2016.
  ista: Hu F, Rishishwar L, Sivadas A, Mitchell G, King J, Murphy T, Gilsdorf J, Mayer
    L, Wang X. 2016. Comparative genomic analysis of Haemophilus haemolyticus and
    nontypeable Haemophilus influenzae and a new testing scheme for their discrimination.
    Journal of Clinical Microbiology. 54(12), 3010–3017.
  mla: Hu, Fang, et al. “Comparative Genomic Analysis of Haemophilus Haemolyticus
    and Nontypeable Haemophilus Influenzae and a New Testing Scheme for Their Discrimination.”
    <i>Journal of Clinical Microbiology</i>, vol. 54, no. 12, American Society for
    Microbiology, 2016, pp. 3010–17, doi:<a href="https://doi.org/10.1128/JCM.01511-16">10.1128/JCM.01511-16</a>.
  short: F. Hu, L. Rishishwar, A. Sivadas, G. Mitchell, J. King, T. Murphy, J. Gilsdorf,
    L. Mayer, X. Wang, Journal of Clinical Microbiology 54 (2016) 3010–3017.
date_created: 2018-12-11T11:50:41Z
date_published: 2016-12-01T00:00:00Z
date_updated: 2021-01-12T06:49:04Z
day: '01'
department:
- _id: GaTk
doi: 10.1128/JCM.01511-16
intvolume: '        54'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121393/
month: '12'
oa: 1
oa_version: Submitted Version
page: 3010 - 3017
publication: Journal of Clinical Microbiology
publication_status: published
publisher: American Society for Microbiology
publist_id: '6146'
quality_controlled: '1'
scopus_import: 1
status: public
title: Comparative genomic analysis of Haemophilus haemolyticus and nontypeable Haemophilus
  influenzae and a new testing scheme for their discrimination
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2016'
...
