---
_id: '1329'
abstract:
- lang: eng
  text: Daphnia species have become models for ecological genomics and exhibit interesting
    features, such as high phenotypic plasticity and a densely packed genome with
    many lineage-specific genes. They are also cyclic parthenogenetic, with alternating
    asexual and sexual cycles and environmental sex determination. Here, we present
    a de novo transcriptome assembly of over 32,000 D. galeata genes and use it to
    investigate gene expression in females and spontaneously produced males of two
    clonal lines derived from lakes in Germany and the Czech Republic. We find that
    only a low percentage (18%) of genes shows sex-biased expression and that there
    are many more female-biased gene (FBG) than male-biased gene (MBG). Furthermore,
    FBGs tend to be more conserved between species than MBGs in both sequence and
    expression. These patterns may be a consequence of cyclic parthenogenesis leading
    to a relaxation of purifying selection on MBGs. The two clonal lines show considerable
    differences in both number and identity of sex-biased genes, suggesting that they
    may have reproductive strategies differing in their investment in sexual reproduction.
    Orthologs of key genes in the sex determination and juvenile hormone pathways,
    which are thought to be important for the transition from asexual to sexual reproduction,
    are present in D. galeata and highly conserved among Daphnia species.
acknowledgement: This study was financially supported by individual grants from the
  Volkswagen Stiftung (to M.C.), the Deutsche Forschungsgemeinschaft (grant PA 903/6
  to J.P.) and the DAAD (to A.K.H.). The authors would like to thank I. Schrank, L.
  Theodosiou, M. Kredler, C. Laforsch, J. Wolinska, J. Griebel, R. Jaenichen, and
  K. Otte for providing the necessary resources and help for maintaining Daphnia cultures
  in the laboratory. H. Lainer supported us for the molecular laboratory work. D.
  Gilbert and J. K. Colbourne contributed ideas for the bioinformatics analysis, and
  L. Hardulak did the orthology mapping including more insect species. This study
  was financially supported by individual grants from the Volkswagen Stiftung (to
  M.C.), the Deutsche Forschungsgemeinschaft (grant PA 903/6 to J.P.) and the DAAD
  (to A.K.H.). This work benefits from and contributes to the Daphnia Genomics Consortium.
author:
- first_name: Ann K
  full_name: Huylmans, Ann K
  id: 4C0A3874-F248-11E8-B48F-1D18A9856A87
  last_name: Huylmans
  orcid: 0000-0001-8871-4961
- first_name: Alberto
  full_name: López Ezquerra, Alberto
  last_name: López Ezquerra
- first_name: John
  full_name: Parsch, John
  last_name: Parsch
- first_name: Mathilde
  full_name: Cordellier, Mathilde
  last_name: Cordellier
citation:
  ama: Huylmans AK, López Ezquerra A, Parsch J, Cordellier M. De novo transcriptome
    assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia
    galeata. <i>Genome Biology and Evolution</i>. 2016;8(10):3120-3139. doi:<a href="https://doi.org/10.1093/gbe/evw221">10.1093/gbe/evw221</a>
  apa: Huylmans, A. K., López Ezquerra, A., Parsch, J., &#38; Cordellier, M. (2016).
    De novo transcriptome assembly and sex-biased gene expression in the cyclical
    parthenogenetic Daphnia galeata. <i>Genome Biology and Evolution</i>. Oxford University
    Press. <a href="https://doi.org/10.1093/gbe/evw221">https://doi.org/10.1093/gbe/evw221</a>
  chicago: Huylmans, Ann K, Alberto López Ezquerra, John Parsch, and Mathilde Cordellier.
    “De Novo Transcriptome Assembly and Sex-Biased Gene Expression in the Cyclical
    Parthenogenetic Daphnia Galeata.” <i>Genome Biology and Evolution</i>. Oxford
    University Press, 2016. <a href="https://doi.org/10.1093/gbe/evw221">https://doi.org/10.1093/gbe/evw221</a>.
  ieee: A. K. Huylmans, A. López Ezquerra, J. Parsch, and M. Cordellier, “De novo
    transcriptome assembly and sex-biased gene expression in the cyclical parthenogenetic
    Daphnia galeata,” <i>Genome Biology and Evolution</i>, vol. 8, no. 10. Oxford
    University Press, pp. 3120–3139, 2016.
  ista: Huylmans AK, López Ezquerra A, Parsch J, Cordellier M. 2016. De novo transcriptome
    assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia
    galeata. Genome Biology and Evolution. 8(10), 3120–3139.
  mla: Huylmans, Ann K., et al. “De Novo Transcriptome Assembly and Sex-Biased Gene
    Expression in the Cyclical Parthenogenetic Daphnia Galeata.” <i>Genome Biology
    and Evolution</i>, vol. 8, no. 10, Oxford University Press, 2016, pp. 3120–39,
    doi:<a href="https://doi.org/10.1093/gbe/evw221">10.1093/gbe/evw221</a>.
  short: A.K. Huylmans, A. López Ezquerra, J. Parsch, M. Cordellier, Genome Biology
    and Evolution 8 (2016) 3120–3139.
date_created: 2018-12-11T11:51:24Z
date_published: 2016-10-01T00:00:00Z
date_updated: 2021-01-12T06:49:55Z
day: '01'
ddc:
- '576'
department:
- _id: BeVi
doi: 10.1093/gbe/evw221
file:
- access_level: open_access
  checksum: 25c7adcb452d39d3b6343ff4b57a652d
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:12:06Z
  date_updated: 2020-07-14T12:44:44Z
  file_id: '4924'
  file_name: IST-2016-663-v1+1_Genome_Biol_Evol-2016-Huylmans-3120-39.pdf
  file_size: 1406265
  relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: '         8'
issue: '10'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: 3120 - 3139
publication: Genome Biology and Evolution
publication_status: published
publisher: Oxford University Press
publist_id: '5940'
pubrep_id: '663'
quality_controlled: '1'
scopus_import: 1
status: public
title: De novo transcriptome assembly and sex-biased gene expression in the cyclical
  parthenogenetic Daphnia galeata
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2016'
...
---
_id: '1330'
abstract:
- lang: eng
  text: In this paper we investigate the existence of closed billiard trajectories
    in not necessarily smooth convex bodies. In particular, we show that if a body
    K ⊂ Rd has the property that the tangent cone of every non-smooth point q ∉ ∂K
    is acute (in a certain sense), then there is a closed billiard trajectory in K.
acknowledgement: Supported by People Programme (Marie Curie Actions) of the European
  Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n°[291734].
  Supported by the Russian Foundation for Basic Research grant 15-31-20403 (mol a
  ved), by the Russian Foundation for Basic Research grant 15-01-99563 A, in part
  by the Moebius Contest Foundation for Young Scientists, and in part by the Simons
  Foundation.
author:
- first_name: Arseniy
  full_name: Akopyan, Arseniy
  id: 430D2C90-F248-11E8-B48F-1D18A9856A87
  last_name: Akopyan
  orcid: 0000-0002-2548-617X
- first_name: Alexey
  full_name: Balitskiy, Alexey
  last_name: Balitskiy
citation:
  ama: Akopyan A, Balitskiy A. Billiards in convex bodies with acute angles. <i>Israel
    Journal of Mathematics</i>. 2016;216(2):833-845. doi:<a href="https://doi.org/10.1007/s11856-016-1429-z">10.1007/s11856-016-1429-z</a>
  apa: Akopyan, A., &#38; Balitskiy, A. (2016). Billiards in convex bodies with acute
    angles. <i>Israel Journal of Mathematics</i>. Springer. <a href="https://doi.org/10.1007/s11856-016-1429-z">https://doi.org/10.1007/s11856-016-1429-z</a>
  chicago: Akopyan, Arseniy, and Alexey Balitskiy. “Billiards in Convex Bodies with
    Acute Angles.” <i>Israel Journal of Mathematics</i>. Springer, 2016. <a href="https://doi.org/10.1007/s11856-016-1429-z">https://doi.org/10.1007/s11856-016-1429-z</a>.
  ieee: A. Akopyan and A. Balitskiy, “Billiards in convex bodies with acute angles,”
    <i>Israel Journal of Mathematics</i>, vol. 216, no. 2. Springer, pp. 833–845,
    2016.
  ista: Akopyan A, Balitskiy A. 2016. Billiards in convex bodies with acute angles.
    Israel Journal of Mathematics. 216(2), 833–845.
  mla: Akopyan, Arseniy, and Alexey Balitskiy. “Billiards in Convex Bodies with Acute
    Angles.” <i>Israel Journal of Mathematics</i>, vol. 216, no. 2, Springer, 2016,
    pp. 833–45, doi:<a href="https://doi.org/10.1007/s11856-016-1429-z">10.1007/s11856-016-1429-z</a>.
  short: A. Akopyan, A. Balitskiy, Israel Journal of Mathematics 216 (2016) 833–845.
date_created: 2018-12-11T11:51:24Z
date_published: 2016-10-15T00:00:00Z
date_updated: 2021-01-12T06:49:56Z
day: '15'
department:
- _id: HeEd
doi: 10.1007/s11856-016-1429-z
ec_funded: 1
intvolume: '       216'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1506.06014
month: '10'
oa: 1
oa_version: Preprint
page: 833 - 845
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Israel Journal of Mathematics
publication_status: published
publisher: Springer
publist_id: '5938'
quality_controlled: '1'
scopus_import: 1
status: public
title: Billiards in convex bodies with acute angles
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 216
year: '2016'
...
---
_id: '1331'
abstract:
- lang: eng
  text: 'Cytokinin is a phytohormone that is well known for its roles in numerous
    plant growth and developmental processes, yet it has also been linked to abiotic
    stress response in a less defined manner. Arabidopsis (Arabidopsis thaliana) Cytokinin
    Response Factor 6 (CRF6) is a cytokinin-responsive AP2/ERF-family transcription
    factor that, through the cytokinin signaling pathway, plays a key role in the
    inhibition of dark-induced senescence. CRF6 expression is also induced by oxidative
    stress, and here we show a novel function for CRF6 in relation to oxidative stress
    and identify downstream transcriptional targets of CRF6 that are repressed in
    response to oxidative stress. Analysis of transcriptomic changes in wild-type
    and crf6 mutant plants treated with H2O2 identified CRF6-dependent differentially
    expressed transcripts, many of which were repressed rather than induced. Moreover,
    many repressed genes also show decreased expression in 35S:CRF6 overexpressing
    plants. Together, these findings suggest that CRF6 functions largely as a transcriptional
    repressor. Interestingly, among the H2O2 repressed CRF6-dependent transcripts
    was a set of five genes associated with cytokinin processes: (signaling) ARR6,
    ARR9, ARR11, (biosynthesis) LOG7, and (transport) ABCG14. We have examined mutants
    of these cytokinin-associated target genes to reveal novel connections to oxidative
    stress. Further examination of CRF6-DNA interactions indicated that CRF6 may regulate
    its targets both directly and indirectly. Together, this shows that CRF6 functions
    during oxidative stress as a negative regulator to control this cytokinin-associated
    module of CRF6- dependent genes and establishes a novel connection between cytokinin
    and oxidative stress response.'
acknowledgement: "This work was financially supported by the following: The Alabama
  Agricultural Experiment Station HATCH grants 370222-310010-2055 and 370225-310006-2055
  for funding to P.J.Z., E.A.K, A.M.P., and A.M.R. P.J.Z. and E.A.K were supported
  by an Auburn University Cellular and Molecular Biosciences Research Fellowship.
  I.D.C. is a postdoctoral fellow of the Research Foundation Flanders (FWO) (FWO/PDO14/043)
  and is also supported by FWO travel\r\ngrant 12N2415N. F.V.B. was supported by grants
  from the Interuniversity Attraction Poles Programme (IUAP P7/29 MARS) initiated
  by the Belgian Science Policy Office and Ghent University (Multidisciplinary Research
  Partnership Biotechnology for a Sustainable Economy, grant 01MRB510W)."
article_processing_charge: No
article_type: original
author:
- first_name: Paul
  full_name: Zwack, Paul
  last_name: Zwack
- first_name: Inge
  full_name: De Clercq, Inge
  last_name: De Clercq
- first_name: Timothy
  full_name: Howton, Timothy
  last_name: Howton
- first_name: H Tucker
  full_name: Hallmark, H Tucker
  last_name: Hallmark
- first_name: Andrej
  full_name: Hurny, Andrej
  id: 4DC4AF46-F248-11E8-B48F-1D18A9856A87
  last_name: Hurny
- first_name: Erika
  full_name: Keshishian, Erika
  last_name: Keshishian
- first_name: Alyssa
  full_name: Parish, Alyssa
  last_name: Parish
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: M Shahid
  full_name: Mukhtar, M Shahid
  last_name: Mukhtar
- first_name: Frank
  full_name: Van Breusegem, Frank
  last_name: Van Breusegem
- first_name: Aaron
  full_name: Rashotte, Aaron
  last_name: Rashotte
citation:
  ama: Zwack P, De Clercq I, Howton T, et al. Cytokinin response factor 6 represses
    cytokinin-associated genes during oxidative stress. <i>Plant Physiology</i>. 2016;172(2):1249-1258.
    doi:<a href="https://doi.org/10.1104/pp.16.00415">10.1104/pp.16.00415</a>
  apa: Zwack, P., De Clercq, I., Howton, T., Hallmark, H. T., Hurny, A., Keshishian,
    E., … Rashotte, A. (2016). Cytokinin response factor 6 represses cytokinin-associated
    genes during oxidative stress. <i>Plant Physiology</i>. American Society of Plant
    Biologists. <a href="https://doi.org/10.1104/pp.16.00415">https://doi.org/10.1104/pp.16.00415</a>
  chicago: Zwack, Paul, Inge De Clercq, Timothy Howton, H Tucker Hallmark, Andrej
    Hurny, Erika Keshishian, Alyssa Parish, et al. “Cytokinin Response Factor 6 Represses
    Cytokinin-Associated Genes during Oxidative Stress.” <i>Plant Physiology</i>.
    American Society of Plant Biologists, 2016. <a href="https://doi.org/10.1104/pp.16.00415">https://doi.org/10.1104/pp.16.00415</a>.
  ieee: P. Zwack <i>et al.</i>, “Cytokinin response factor 6 represses cytokinin-associated
    genes during oxidative stress,” <i>Plant Physiology</i>, vol. 172, no. 2. American
    Society of Plant Biologists, pp. 1249–1258, 2016.
  ista: Zwack P, De Clercq I, Howton T, Hallmark HT, Hurny A, Keshishian E, Parish
    A, Benková E, Mukhtar MS, Van Breusegem F, Rashotte A. 2016. Cytokinin response
    factor 6 represses cytokinin-associated genes during oxidative stress. Plant Physiology.
    172(2), 1249–1258.
  mla: Zwack, Paul, et al. “Cytokinin Response Factor 6 Represses Cytokinin-Associated
    Genes during Oxidative Stress.” <i>Plant Physiology</i>, vol. 172, no. 2, American
    Society of Plant Biologists, 2016, pp. 1249–58, doi:<a href="https://doi.org/10.1104/pp.16.00415">10.1104/pp.16.00415</a>.
  short: P. Zwack, I. De Clercq, T. Howton, H.T. Hallmark, A. Hurny, E. Keshishian,
    A. Parish, E. Benková, M.S. Mukhtar, F. Van Breusegem, A. Rashotte, Plant Physiology
    172 (2016) 1249–1258.
date_created: 2018-12-11T11:51:25Z
date_published: 2016-10-02T00:00:00Z
date_updated: 2022-05-24T09:26:03Z
day: '02'
department:
- _id: EvBe
doi: 10.1104/pp.16.00415
intvolume: '       172'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1104/pp.16.00415
month: '10'
oa: 1
oa_version: Published Version
page: 1249 - 1258
publication: Plant Physiology
publication_identifier:
  eissn:
  - 1532-2548
  issn:
  - 0032-0889
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '5937'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cytokinin response factor 6 represses cytokinin-associated genes during oxidative
  stress
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 172
year: '2016'
...
---
_id: '1332'
abstract:
- lang: eng
  text: Antibiotic-sensitive and -resistant bacteria coexist in natural environments
    with low, if detectable, antibiotic concentrations. Except possibly around localized
    antibiotic sources, where resistance can provide a strong advantage, bacterial
    fitness is dominated by stresses unaffected by resistance to the antibiotic. How
    do such mixed and heterogeneous conditions influence the selective advantage or
    disadvantage of antibiotic resistance? Here we find that sub-inhibitory levels
    of tetracyclines potentiate selection for or against tetracycline resistance around
    localized sources of almost any toxin or stress. Furthermore, certain stresses
    generate alternating rings of selection for and against resistance around a localized
    source of the antibiotic. In these conditions, localized antibiotic sources, even
    at high strengths, can actually produce a net selection against resistance to
    the antibiotic. Our results show that interactions between the effects of an antibiotic
    and other stresses in inhomogeneous environments can generate pervasive, complex
    patterns of selection both for and against antibiotic resistance.
acknowledgement: This work was partially supported by US National Institutes of Health
  grant R01-GM081617, Israeli Centers of Research Excellence I-CORE Program ISF Grant
  No. 152/11, and the European Research Council FP7 ERC Grant 281891.
article_number: '10333'
author:
- first_name: Remy P
  full_name: Chait, Remy P
  id: 3464AE84-F248-11E8-B48F-1D18A9856A87
  last_name: Chait
  orcid: 0000-0003-0876-3187
- first_name: Adam
  full_name: Palmer, Adam
  last_name: Palmer
- first_name: Idan
  full_name: Yelin, Idan
  last_name: Yelin
- first_name: Roy
  full_name: Kishony, Roy
  last_name: Kishony
citation:
  ama: Chait RP, Palmer A, Yelin I, Kishony R. Pervasive selection for and against
    antibiotic resistance in inhomogeneous multistress environments. <i>Nature Communications</i>.
    2016;7. doi:<a href="https://doi.org/10.1038/ncomms10333">10.1038/ncomms10333</a>
  apa: Chait, R. P., Palmer, A., Yelin, I., &#38; Kishony, R. (2016). Pervasive selection
    for and against antibiotic resistance in inhomogeneous multistress environments.
    <i>Nature Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/ncomms10333">https://doi.org/10.1038/ncomms10333</a>
  chicago: Chait, Remy P, Adam Palmer, Idan Yelin, and Roy Kishony. “Pervasive Selection
    for and against Antibiotic Resistance in Inhomogeneous Multistress Environments.”
    <i>Nature Communications</i>. Nature Publishing Group, 2016. <a href="https://doi.org/10.1038/ncomms10333">https://doi.org/10.1038/ncomms10333</a>.
  ieee: R. P. Chait, A. Palmer, I. Yelin, and R. Kishony, “Pervasive selection for
    and against antibiotic resistance in inhomogeneous multistress environments,”
    <i>Nature Communications</i>, vol. 7. Nature Publishing Group, 2016.
  ista: Chait RP, Palmer A, Yelin I, Kishony R. 2016. Pervasive selection for and
    against antibiotic resistance in inhomogeneous multistress environments. Nature
    Communications. 7, 10333.
  mla: Chait, Remy P., et al. “Pervasive Selection for and against Antibiotic Resistance
    in Inhomogeneous Multistress Environments.” <i>Nature Communications</i>, vol.
    7, 10333, Nature Publishing Group, 2016, doi:<a href="https://doi.org/10.1038/ncomms10333">10.1038/ncomms10333</a>.
  short: R.P. Chait, A. Palmer, I. Yelin, R. Kishony, Nature Communications 7 (2016).
date_created: 2018-12-11T11:51:25Z
date_published: 2016-01-20T00:00:00Z
date_updated: 2021-01-12T06:49:57Z
day: '20'
ddc:
- '570'
- '579'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1038/ncomms10333
file:
- access_level: open_access
  checksum: ef147bcbb8bd37e9079cf3ce06f5815d
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:52Z
  date_updated: 2020-07-14T12:44:44Z
  file_id: '5039'
  file_name: IST-2016-662-v1+1_ncomms10333.pdf
  file_size: 1844107
  relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: '         7'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '01'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5936'
pubrep_id: '662'
quality_controlled: '1'
scopus_import: 1
status: public
title: Pervasive selection for and against antibiotic resistance in inhomogeneous
  multistress environments
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...
---
_id: '1333'
abstract:
- lang: eng
  text: Social dilemmas force players to balance between personal and collective gain.
    In many dilemmas, such as elected governments negotiating climate-change mitigation
    measures, the decisions are made not by individual players but by their representatives.
    However, the behaviour of representatives in social dilemmas has not been investigated
    experimentally. Here inspired by the negotiations for greenhouse-gas emissions
    reductions, we experimentally study a collective-risk social dilemma that involves
    representatives deciding on behalf of their fellow group members. Representatives
    can be re-elected or voted out after each consecutive collective-risk game. Selfish
    players are preferentially elected and are hence found most frequently in the
    &quot;representatives&quot; treatment. Across all treatments, we identify the
    selfish players as extortioners. As predicted by our mathematical model, their
    steadfast strategies enforce cooperation from fair players who finally compensate
    almost completely the deficit caused by the extortionate co-players. Everybody
    gains, but the extortionate representatives and their groups gain the most.
acknowledgement: We thank the students for participation; H.-J. Krambeck for writing
  the software for the game; H. Arndt, T. Bakker, L. Becks, H. Brendelberger, S. Dobler
  and T. Reusch for support; and the Max Planck Society for the Advancement of Science
  for funding.
article_number: '10915'
author:
- first_name: Manfred
  full_name: Milinski, Manfred
  last_name: Milinski
- first_name: Christian
  full_name: Hilbe, Christian
  id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
  last_name: Hilbe
  orcid: 0000-0001-5116-955X
- first_name: Dirk
  full_name: Semmann, Dirk
  last_name: Semmann
- first_name: Ralf
  full_name: Sommerfeld, Ralf
  last_name: Sommerfeld
- first_name: Jochem
  full_name: Marotzke, Jochem
  last_name: Marotzke
citation:
  ama: Milinski M, Hilbe C, Semmann D, Sommerfeld R, Marotzke J. Humans choose representatives
    who enforce cooperation in social dilemmas through extortion. <i>Nature Communications</i>.
    2016;7. doi:<a href="https://doi.org/10.1038/ncomms10915">10.1038/ncomms10915</a>
  apa: Milinski, M., Hilbe, C., Semmann, D., Sommerfeld, R., &#38; Marotzke, J. (2016).
    Humans choose representatives who enforce cooperation in social dilemmas through
    extortion. <i>Nature Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/ncomms10915">https://doi.org/10.1038/ncomms10915</a>
  chicago: Milinski, Manfred, Christian Hilbe, Dirk Semmann, Ralf Sommerfeld, and
    Jochem Marotzke. “Humans Choose Representatives Who Enforce Cooperation in Social
    Dilemmas through Extortion.” <i>Nature Communications</i>. Nature Publishing Group,
    2016. <a href="https://doi.org/10.1038/ncomms10915">https://doi.org/10.1038/ncomms10915</a>.
  ieee: M. Milinski, C. Hilbe, D. Semmann, R. Sommerfeld, and J. Marotzke, “Humans
    choose representatives who enforce cooperation in social dilemmas through extortion,”
    <i>Nature Communications</i>, vol. 7. Nature Publishing Group, 2016.
  ista: Milinski M, Hilbe C, Semmann D, Sommerfeld R, Marotzke J. 2016. Humans choose
    representatives who enforce cooperation in social dilemmas through extortion.
    Nature Communications. 7, 10915.
  mla: Milinski, Manfred, et al. “Humans Choose Representatives Who Enforce Cooperation
    in Social Dilemmas through Extortion.” <i>Nature Communications</i>, vol. 7, 10915,
    Nature Publishing Group, 2016, doi:<a href="https://doi.org/10.1038/ncomms10915">10.1038/ncomms10915</a>.
  short: M. Milinski, C. Hilbe, D. Semmann, R. Sommerfeld, J. Marotzke, Nature Communications
    7 (2016).
date_created: 2018-12-11T11:51:25Z
date_published: 2016-03-07T00:00:00Z
date_updated: 2021-01-12T06:49:57Z
day: '07'
ddc:
- '519'
- '530'
- '599'
department:
- _id: KrCh
doi: 10.1038/ncomms10915
file:
- access_level: open_access
  checksum: 9ea0d7ce59a555a1cb8353d5559407cb
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:44Z
  date_updated: 2020-07-14T12:44:44Z
  file_id: '4834'
  file_name: IST-2016-661-v1+1_ncomms10915.pdf
  file_size: 1432577
  relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: '         7'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5935'
pubrep_id: '661'
quality_controlled: '1'
scopus_import: 1
status: public
title: Humans choose representatives who enforce cooperation in social dilemmas through
  extortion
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...
---
_id: '1334'
abstract:
- lang: eng
  text: Hippocampal neurons encode a cognitive map of space. These maps are thought
    to be updated during learning and in response to changes in the environment through
    activity-dependent synaptic plasticity. Here we examine how changes in activity
    influence spatial coding in rats using halorhodopsin-mediated, spatially selective
    optogenetic silencing. Halorhoposin stimulation leads to light-induced suppression
    in many place cells and interneurons; some place cells increase their firing through
    disinhibition, whereas some show no effect. We find that place fields of the unaffected
    subpopulation remain stable. On the other hand, place fields of suppressed place
    cells were unstable, showing remapping across sessions before and after optogenetic
    inhibition. Disinhibited place cells had stable maps but sustained an elevated
    firing rate. These findings suggest that place representation in the hippocampus
    is constantly governed by activity-dependent processes, and that disinhibition
    may provide a mechanism for rate remapping.
article_number: '11824'
author:
- first_name: Philipp
  full_name: Schönenberger, Philipp
  id: 3B9D816C-F248-11E8-B48F-1D18A9856A87
  last_name: Schönenberger
- first_name: Joseph
  full_name: O'Neill, Joseph
  id: 426376DC-F248-11E8-B48F-1D18A9856A87
  last_name: O'Neill
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
citation:
  ama: Schönenberger P, O’Neill J, Csicsvari JL. Activity dependent plasticity of
    hippocampal place maps. <i>Nature Communications</i>. 2016;7. doi:<a href="https://doi.org/10.1038/ncomms11824">10.1038/ncomms11824</a>
  apa: Schönenberger, P., O’Neill, J., &#38; Csicsvari, J. L. (2016). Activity dependent
    plasticity of hippocampal place maps. <i>Nature Communications</i>. Nature Publishing
    Group. <a href="https://doi.org/10.1038/ncomms11824">https://doi.org/10.1038/ncomms11824</a>
  chicago: Schönenberger, Philipp, Joseph O’Neill, and Jozsef L Csicsvari. “Activity
    Dependent Plasticity of Hippocampal Place Maps.” <i>Nature Communications</i>.
    Nature Publishing Group, 2016. <a href="https://doi.org/10.1038/ncomms11824">https://doi.org/10.1038/ncomms11824</a>.
  ieee: P. Schönenberger, J. O’Neill, and J. L. Csicsvari, “Activity dependent plasticity
    of hippocampal place maps,” <i>Nature Communications</i>, vol. 7. Nature Publishing
    Group, 2016.
  ista: Schönenberger P, O’Neill J, Csicsvari JL. 2016. Activity dependent plasticity
    of hippocampal place maps. Nature Communications. 7, 11824.
  mla: Schönenberger, Philipp, et al. “Activity Dependent Plasticity of Hippocampal
    Place Maps.” <i>Nature Communications</i>, vol. 7, 11824, Nature Publishing Group,
    2016, doi:<a href="https://doi.org/10.1038/ncomms11824">10.1038/ncomms11824</a>.
  short: P. Schönenberger, J. O’Neill, J.L. Csicsvari, Nature Communications 7 (2016).
date_created: 2018-12-11T11:51:26Z
date_published: 2016-06-10T00:00:00Z
date_updated: 2021-01-12T06:49:57Z
day: '10'
ddc:
- '570'
department:
- _id: JoCs
doi: 10.1038/ncomms11824
ec_funded: 1
file:
- access_level: open_access
  checksum: e43307754abe65b840a21939fe163618
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:16:10Z
  date_updated: 2020-07-14T12:44:44Z
  file_id: '5196'
  file_name: IST-2016-660-v1+1_ncomms11824.pdf
  file_size: 1793846
  relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: '         7'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 257A4776-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '281511'
  name: Memory-related information processing in neuronal circuits of the hippocampus
    and entorhinal cortex
- _id: 257D4372-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I2072-B27
  name: Interneuron plasticity during spatial learning
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5934'
pubrep_id: '660'
quality_controlled: '1'
scopus_import: 1
status: public
title: Activity dependent plasticity of hippocampal place maps
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...
---
_id: '1335'
abstract:
- lang: eng
  text: In this paper we review various automata-theoretic formalisms for expressing
    quantitative properties. We start with finite-state Boolean automata that express
    the traditional regular properties. We then consider weighted ω-automata that
    can measure the average density of events, which finite-state Boolean automata
    cannot. However, even weighted ω-automata cannot express basic performance properties
    like average response time. We finally consider two formalisms of weighted ω-automata
    with monitors, where the monitors are either (a) counters or (b) weighted automata
    themselves. We present a translation result to establish that these two formalisms
    are equivalent. Weighted ω-automata with monitors generalize weighted ω-automata,
    and can express average response time property. They present a natural, robust,
    and expressive framework for quantitative specifications, with important decidable
    properties.
alternative_title:
- LNCS
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Jan
  full_name: Otop, Jan
  id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
  last_name: Otop
citation:
  ama: 'Chatterjee K, Henzinger TA, Otop J. Quantitative monitor automata. In: Vol
    9837. Springer; 2016:23-38. doi:<a href="https://doi.org/10.1007/978-3-662-53413-7_2">10.1007/978-3-662-53413-7_2</a>'
  apa: 'Chatterjee, K., Henzinger, T. A., &#38; Otop, J. (2016). Quantitative monitor
    automata (Vol. 9837, pp. 23–38). Presented at the SAS: Static Analysis Symposium,
    Edinburgh, United Kingdom: Springer. <a href="https://doi.org/10.1007/978-3-662-53413-7_2">https://doi.org/10.1007/978-3-662-53413-7_2</a>'
  chicago: Chatterjee, Krishnendu, Thomas A Henzinger, and Jan Otop. “Quantitative
    Monitor Automata,” 9837:23–38. Springer, 2016. <a href="https://doi.org/10.1007/978-3-662-53413-7_2">https://doi.org/10.1007/978-3-662-53413-7_2</a>.
  ieee: 'K. Chatterjee, T. A. Henzinger, and J. Otop, “Quantitative monitor automata,”
    presented at the SAS: Static Analysis Symposium, Edinburgh, United Kingdom, 2016,
    vol. 9837, pp. 23–38.'
  ista: 'Chatterjee K, Henzinger TA, Otop J. 2016. Quantitative monitor automata.
    SAS: Static Analysis Symposium, LNCS, vol. 9837, 23–38.'
  mla: Chatterjee, Krishnendu, et al. <i>Quantitative Monitor Automata</i>. Vol. 9837,
    Springer, 2016, pp. 23–38, doi:<a href="https://doi.org/10.1007/978-3-662-53413-7_2">10.1007/978-3-662-53413-7_2</a>.
  short: K. Chatterjee, T.A. Henzinger, J. Otop, in:, Springer, 2016, pp. 23–38.
conference:
  end_date: 2016-09-10
  location: Edinburgh, United Kingdom
  name: 'SAS: Static Analysis Symposium'
  start_date: 2016-09-08
date_created: 2018-12-11T11:51:26Z
date_published: 2016-08-31T00:00:00Z
date_updated: 2021-01-12T06:49:58Z
day: '31'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-662-53413-7_2
ec_funded: 1
intvolume: '      9837'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1604.06764
month: '08'
oa: 1
oa_version: Preprint
page: 23 - 38
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
publication_status: published
publisher: Springer
publist_id: '5932'
quality_controlled: '1'
scopus_import: 1
status: public
title: Quantitative monitor automata
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 9837
year: '2016'
...
---
_id: '8241'
abstract:
- lang: eng
  text: 'Background: Anticancer vaccines could represent a valuable complementary
    strategy to established therapies, especially in settings of early stage and minimal
    residual disease. HER-2 is an important target for immunotherapy and addressed
    by the monoclonal antibody trastuzumab. We have previously generated HER-2 mimotope
    peptides from phage display libraries. The synthesized peptides were coupled to
    carriers and applied for epitope-specific induction of trastuzumab-like IgG. For
    simplification and to avoid methodological limitations of synthesis and coupling
    chemistry, we herewith present a novel and optimized approach by using adeno-associated
    viruses (AAV) as effective and high-density mimotope-display system, which can
    be directly used for vaccination. Methods: An AAV capsid display library was constructed
    by genetically incorporating random peptides in a plasmid encoding the wild-type
    AAV2 capsid protein. AAV clones, expressing peptides specifically reactive to
    trastuzumab, were employed to immunize BALB/c mice. Antibody titers against human
    HER-2 were determined, and the isotype composition and functional properties of
    these were tested. Finally, prophylactically immunized mice were challenged with
    human HER-2 transfected mouse D2F2/E2 cells. Results: HER-2 mimotope AAV-vaccines
    induced antibodies specific to human HER-2. Two clones were selected for immunization
    of mice, which were subsequently grafted D2F2/E2 cells. Both mimotope AAV clones
    delayed the growth of tumors significantly, as compared to controls. Conclusion:
    In this study, a novel mimotope AAV-based platform was created allowing the isolation
    of mimotopes, which can be directly used as anticancer vaccines. The example of
    trastuzumab AAV-mimotopes demonstrates that this vaccine strategy could help to
    establish active immunotherapy for breast-cancer patients.'
article_number: e1171446
article_processing_charge: No
article_type: original
author:
- first_name: Josef
  full_name: Singer, Josef
  last_name: Singer
- first_name: Krisztina
  full_name: Manzano-Szalai, Krisztina
  last_name: Manzano-Szalai
- first_name: Judit
  full_name: Fazekas, Judit
  id: 36432834-F248-11E8-B48F-1D18A9856A87
  last_name: Fazekas
  orcid: 0000-0002-8777-3502
- first_name: Kathrin
  full_name: Thell, Kathrin
  last_name: Thell
- first_name: Anna
  full_name: Bentley-Lukschal, Anna
  last_name: Bentley-Lukschal
- first_name: Caroline
  full_name: Stremnitzer, Caroline
  last_name: Stremnitzer
- first_name: Franziska
  full_name: Roth-Walter, Franziska
  last_name: Roth-Walter
- first_name: Margit
  full_name: Weghofer, Margit
  last_name: Weghofer
- first_name: Mirko
  full_name: Ritter, Mirko
  last_name: Ritter
- first_name: Kerstin
  full_name: Pino Tossi, Kerstin
  last_name: Pino Tossi
- first_name: Markus
  full_name: Hörer, Markus
  last_name: Hörer
- first_name: Uwe
  full_name: Michaelis, Uwe
  last_name: Michaelis
- first_name: Erika
  full_name: Jensen-Jarolim, Erika
  last_name: Jensen-Jarolim
citation:
  ama: Singer J, Manzano-Szalai K, Singer J, et al. Proof of concept study with an
    HER-2 mimotope anticancer vaccine deduced from a novel AAV-mimotope library platform.
    <i>OncoImmunology</i>. 2016;5(7). doi:<a href="https://doi.org/10.1080/2162402x.2016.1171446">10.1080/2162402x.2016.1171446</a>
  apa: Singer, J., Manzano-Szalai, K., Singer, J., Thell, K., Bentley-Lukschal, A.,
    Stremnitzer, C., … Jensen-Jarolim, E. (2016). Proof of concept study with an HER-2
    mimotope anticancer vaccine deduced from a novel AAV-mimotope library platform.
    <i>OncoImmunology</i>. Taylor &#38; Francis. <a href="https://doi.org/10.1080/2162402x.2016.1171446">https://doi.org/10.1080/2162402x.2016.1171446</a>
  chicago: Singer, Josef, Krisztina Manzano-Szalai, Judit Singer, Kathrin Thell, Anna
    Bentley-Lukschal, Caroline Stremnitzer, Franziska Roth-Walter, et al. “Proof of
    Concept Study with an HER-2 Mimotope Anticancer Vaccine Deduced from a Novel AAV-Mimotope
    Library Platform.” <i>OncoImmunology</i>. Taylor &#38; Francis, 2016. <a href="https://doi.org/10.1080/2162402x.2016.1171446">https://doi.org/10.1080/2162402x.2016.1171446</a>.
  ieee: J. Singer <i>et al.</i>, “Proof of concept study with an HER-2 mimotope anticancer
    vaccine deduced from a novel AAV-mimotope library platform,” <i>OncoImmunology</i>,
    vol. 5, no. 7. Taylor &#38; Francis, 2016.
  ista: Singer J, Manzano-Szalai K, Singer J, Thell K, Bentley-Lukschal A, Stremnitzer
    C, Roth-Walter F, Weghofer M, Ritter M, Pino Tossi K, Hörer M, Michaelis U, Jensen-Jarolim
    E. 2016. Proof of concept study with an HER-2 mimotope anticancer vaccine deduced
    from a novel AAV-mimotope library platform. OncoImmunology. 5(7), e1171446.
  mla: Singer, Josef, et al. “Proof of Concept Study with an HER-2 Mimotope Anticancer
    Vaccine Deduced from a Novel AAV-Mimotope Library Platform.” <i>OncoImmunology</i>,
    vol. 5, no. 7, e1171446, Taylor &#38; Francis, 2016, doi:<a href="https://doi.org/10.1080/2162402x.2016.1171446">10.1080/2162402x.2016.1171446</a>.
  short: J. Singer, K. Manzano-Szalai, J. Singer, K. Thell, A. Bentley-Lukschal, C.
    Stremnitzer, F. Roth-Walter, M. Weghofer, M. Ritter, K. Pino Tossi, M. Hörer,
    U. Michaelis, E. Jensen-Jarolim, OncoImmunology 5 (2016).
date_created: 2020-08-10T11:54:03Z
date_published: 2016-06-30T00:00:00Z
date_updated: 2021-01-12T08:17:41Z
day: '30'
doi: 10.1080/2162402x.2016.1171446
extern: '1'
intvolume: '         5'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1080/2162402X.2016.1171446
month: '06'
oa: 1
oa_version: Published Version
publication: OncoImmunology
publication_identifier:
  issn:
  - 2162-402X
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
status: public
title: Proof of concept study with an HER-2 mimotope anticancer vaccine deduced from
  a novel AAV-mimotope library platform
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2016'
...
---
_id: '8302'
abstract:
- lang: eng
  text: While showing great promise, Bitcoin requires users to wait tens of minutes
    for transactions to commit, and even then, offering only probabilistic guarantees.
    This paper introduces ByzCoin, a novel Byzantine consensus protocol that leverages
    scalable collective signing to commit Bitcoin transactions irreversibly within
    seconds. ByzCoin achieves Byzantine consensus while preserving Bitcoin’s open
    membership by dynamically forming hash power-proportionate consensus groups that
    represent recently-successful block miners. ByzCoin employs communication trees
    to optimize transaction commitment and verification under normal operation while
    guaranteeing safety and liveness under Byzantine faults, up to a near-optimal
    tolerance of f faulty group members among 3f + 2 total. ByzCoin mitigates double
    spending and selfish mining attacks by producing collectively signed transaction
    blocks within one minute of transaction submission. Tree-structured communication
    further reduces this latency to less than 30 seconds. Due to these optimizations,
    ByzCoin achieves a throughput higher than Paypal currently handles, with a confirmation
    latency of 15-20 seconds.
article_processing_charge: No
arxiv: 1
author:
- first_name: Eleftherios
  full_name: Kokoris Kogias, Eleftherios
  id: f5983044-d7ef-11ea-ac6d-fd1430a26d30
  last_name: Kokoris Kogias
- first_name: Philipp
  full_name: Jovanovic, Philipp
  last_name: Jovanovic
- first_name: Nicolas
  full_name: Gailly, Nicolas
  last_name: Gailly
- first_name: Ismail
  full_name: Khoffi, Ismail
  last_name: Khoffi
- first_name: Linus
  full_name: Gasser, Linus
  last_name: Gasser
- first_name: Bryan
  full_name: Ford, Bryan
  last_name: Ford
citation:
  ama: 'Kokoris Kogias E, Jovanovic P, Gailly N, Khoffi I, Gasser L, Ford B. Enhancing
    bitcoin security and performance with strong consistency via collective signing.
    In: <i>Proceedings of the 25th USENIX Conference on Security Symposium</i>. USENIX
    Association; 2016:279–296.'
  apa: 'Kokoris Kogias, E., Jovanovic, P., Gailly, N., Khoffi, I., Gasser, L., &#38;
    Ford, B. (2016). Enhancing bitcoin security and performance with strong consistency
    via collective signing. In <i>Proceedings of the 25th USENIX Conference on Security
    Symposium</i> (pp. 279–296). Austin, TX, United States: USENIX Association.'
  chicago: Kokoris Kogias, Eleftherios, Philipp Jovanovic, Nicolas Gailly, Ismail
    Khoffi, Linus Gasser, and Bryan Ford. “Enhancing Bitcoin Security and Performance
    with Strong Consistency via Collective Signing.” In <i>Proceedings of the 25th
    USENIX Conference on Security Symposium</i>, 279–296. USENIX Association, 2016.
  ieee: E. Kokoris Kogias, P. Jovanovic, N. Gailly, I. Khoffi, L. Gasser, and B. Ford,
    “Enhancing bitcoin security and performance with strong consistency via collective
    signing,” in <i>Proceedings of the 25th USENIX Conference on Security Symposium</i>,
    Austin, TX, United States, 2016, pp. 279–296.
  ista: 'Kokoris Kogias E, Jovanovic P, Gailly N, Khoffi I, Gasser L, Ford B. 2016.
    Enhancing bitcoin security and performance with strong consistency via collective
    signing. Proceedings of the 25th USENIX Conference on Security Symposium. SEC:
    Security Symposium, 279–296.'
  mla: Kokoris Kogias, Eleftherios, et al. “Enhancing Bitcoin Security and Performance
    with Strong Consistency via Collective Signing.” <i>Proceedings of the 25th USENIX
    Conference on Security Symposium</i>, USENIX Association, 2016, pp. 279–296.
  short: E. Kokoris Kogias, P. Jovanovic, N. Gailly, I. Khoffi, L. Gasser, B. Ford,
    in:, Proceedings of the 25th USENIX Conference on Security Symposium, USENIX Association,
    2016, pp. 279–296.
conference:
  end_date: 2016-08-12
  location: Austin, TX, United States
  name: 'SEC: Security Symposium'
  start_date: 2016-08-10
date_created: 2020-08-26T12:08:35Z
date_published: 2016-09-01T00:00:00Z
date_updated: 2021-01-12T08:18:00Z
day: '01'
extern: '1'
external_id:
  arxiv:
  - '1602.06997'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1602.06997
month: '09'
oa: 1
oa_version: Published Version
page: 279–296
publication: Proceedings of the 25th USENIX Conference on Security Symposium
publication_identifier:
  isbn:
  - '9781931971324'
publication_status: published
publisher: USENIX Association
quality_controlled: '1'
status: public
title: Enhancing bitcoin security and performance with strong consistency via collective
  signing
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '9019'
abstract:
- lang: eng
  text: Targeting protein–protein interactions has long been considered as a very
    difficult if impossible task, but over the past decade, front lines have moved.
    The number of successful examples is exponentially growing. This review presents
    a rapid overview of recent advances in this field considering the strengths and
    weaknesses of the small molecule approaches and alternative strategies such as
    the selection or design of artificial antibodies, peptides or peptidomimetics.
- lang: fre
  text: Cibler les interactions protéine–protéine a longtemps été considéré comme
    une tâche très difficile, voire impossible, mais, depuis les dix dernières années,
    les lignes ont bougé. Le nombre d’exemples de réussites s’accroît exponentiellement.
    Cette revue présente un rapide panorama des avancées récentes dans ce domaine,
    considérant les forces et les faiblesses de l’approche « petite molécule » ainsi
    que des stratégies alternatives comme la sélection ou le design d’anticorps artificiels,
    de peptides ou de peptidomimétiques.
article_processing_charge: No
article_type: original
author:
- first_name: May M
  full_name: Bakail, May M
  id: FB3C3F8E-522F-11EA-B186-22963DDC885E
  last_name: Bakail
  orcid: 0000-0002-9592-1587
- first_name: Francoise
  full_name: Ochsenbein, Francoise
  last_name: Ochsenbein
citation:
  ama: Bakail MM, Ochsenbein F. Targeting protein–protein interactions, a wide open
    field for drug design. <i>Comptes Rendus Chimie</i>. 2016;19(1-2):19-27. doi:<a
    href="https://doi.org/10.1016/j.crci.2015.12.004">10.1016/j.crci.2015.12.004</a>
  apa: Bakail, M. M., &#38; Ochsenbein, F. (2016). Targeting protein–protein interactions,
    a wide open field for drug design. <i>Comptes Rendus Chimie</i>. Elsevier. <a
    href="https://doi.org/10.1016/j.crci.2015.12.004">https://doi.org/10.1016/j.crci.2015.12.004</a>
  chicago: Bakail, May M, and Francoise Ochsenbein. “Targeting Protein–Protein Interactions,
    a Wide Open Field for Drug Design.” <i>Comptes Rendus Chimie</i>. Elsevier, 2016.
    <a href="https://doi.org/10.1016/j.crci.2015.12.004">https://doi.org/10.1016/j.crci.2015.12.004</a>.
  ieee: M. M. Bakail and F. Ochsenbein, “Targeting protein–protein interactions, a
    wide open field for drug design,” <i>Comptes Rendus Chimie</i>, vol. 19, no. 1–2.
    Elsevier, pp. 19–27, 2016.
  ista: Bakail MM, Ochsenbein F. 2016. Targeting protein–protein interactions, a wide
    open field for drug design. Comptes Rendus Chimie. 19(1–2), 19–27.
  mla: Bakail, May M., and Francoise Ochsenbein. “Targeting Protein–Protein Interactions,
    a Wide Open Field for Drug Design.” <i>Comptes Rendus Chimie</i>, vol. 19, no.
    1–2, Elsevier, 2016, pp. 19–27, doi:<a href="https://doi.org/10.1016/j.crci.2015.12.004">10.1016/j.crci.2015.12.004</a>.
  short: M.M. Bakail, F. Ochsenbein, Comptes Rendus Chimie 19 (2016) 19–27.
date_created: 2021-01-19T11:11:54Z
date_published: 2016-02-06T00:00:00Z
date_updated: 2023-02-23T13:46:55Z
day: '06'
ddc:
- '570'
doi: 10.1016/j.crci.2015.12.004
extern: '1'
file:
- access_level: open_access
  checksum: c262814ffdbfe95900256ab9ff42cdf5
  content_type: application/pdf
  creator: dernst
  date_created: 2021-01-22T12:36:52Z
  date_updated: 2021-01-22T12:36:52Z
  file_id: '9035'
  file_name: 2016_ComptesRendueChimie_Bakail.pdf
  file_size: 2045260
  relation: main_file
  success: 1
file_date_updated: 2021-01-22T12:36:52Z
has_accepted_license: '1'
intvolume: '        19'
issue: 1-2
keyword:
- General Chemistry
- General Chemical Engineering
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '02'
oa: 1
oa_version: Published Version
page: 19-27
publication: Comptes Rendus Chimie
publication_identifier:
  issn:
  - 1631-0748
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Targeting protein–protein interactions, a wide open field for drug design
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2016'
...
---
_id: '9051'
abstract:
- lang: eng
  text: 'Biological systems often involve the self-assembly of basic components into
    complex and functioning structures. Artificial systems that mimic such processes
    can provide a well-controlled setting to explore the principles involved and also
    synthesize useful micromachines. Our experiments show that immotile, but active,
    components self-assemble into two types of structure that exhibit the fundamental
    forms of motility: translation and rotation. Specifically, micron-scale metallic
    rods are designed to induce extensile surface flows in the presence of a chemical
    fuel; these rods interact with each other and pair up to form either a swimmer
    or a rotor. Such pairs can transition reversibly between these two configurations,
    leading to kinetics reminiscent of bacterial run-and-tumble motion.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Megan S.
  full_name: Davies Wykes, Megan S.
  last_name: Davies Wykes
- first_name: Jérémie A
  full_name: Palacci, Jérémie A
  id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
  last_name: Palacci
  orcid: 0000-0002-7253-9465
- first_name: Takuji
  full_name: Adachi, Takuji
  last_name: Adachi
- first_name: Leif
  full_name: Ristroph, Leif
  last_name: Ristroph
- first_name: Xiao
  full_name: Zhong, Xiao
  last_name: Zhong
- first_name: Michael D.
  full_name: Ward, Michael D.
  last_name: Ward
- first_name: Jun
  full_name: Zhang, Jun
  last_name: Zhang
- first_name: Michael J.
  full_name: Shelley, Michael J.
  last_name: Shelley
citation:
  ama: Davies Wykes MS, Palacci JA, Adachi T, et al. Dynamic self-assembly of microscale
    rotors and swimmers. <i>Soft Matter</i>. 2016;12(20):4584-4589. doi:<a href="https://doi.org/10.1039/c5sm03127c">10.1039/c5sm03127c</a>
  apa: Davies Wykes, M. S., Palacci, J. A., Adachi, T., Ristroph, L., Zhong, X., Ward,
    M. D., … Shelley, M. J. (2016). Dynamic self-assembly of microscale rotors and
    swimmers. <i>Soft Matter</i>. Royal Society of Chemistry. <a href="https://doi.org/10.1039/c5sm03127c">https://doi.org/10.1039/c5sm03127c</a>
  chicago: Davies Wykes, Megan S., Jérémie A Palacci, Takuji Adachi, Leif Ristroph,
    Xiao Zhong, Michael D. Ward, Jun Zhang, and Michael J. Shelley. “Dynamic Self-Assembly
    of Microscale Rotors and Swimmers.” <i>Soft Matter</i>. Royal Society of Chemistry,
    2016. <a href="https://doi.org/10.1039/c5sm03127c">https://doi.org/10.1039/c5sm03127c</a>.
  ieee: M. S. Davies Wykes <i>et al.</i>, “Dynamic self-assembly of microscale rotors
    and swimmers,” <i>Soft Matter</i>, vol. 12, no. 20. Royal Society of Chemistry,
    pp. 4584–4589, 2016.
  ista: Davies Wykes MS, Palacci JA, Adachi T, Ristroph L, Zhong X, Ward MD, Zhang
    J, Shelley MJ. 2016. Dynamic self-assembly of microscale rotors and swimmers.
    Soft Matter. 12(20), 4584–4589.
  mla: Davies Wykes, Megan S., et al. “Dynamic Self-Assembly of Microscale Rotors
    and Swimmers.” <i>Soft Matter</i>, vol. 12, no. 20, Royal Society of Chemistry,
    2016, pp. 4584–89, doi:<a href="https://doi.org/10.1039/c5sm03127c">10.1039/c5sm03127c</a>.
  short: M.S. Davies Wykes, J.A. Palacci, T. Adachi, L. Ristroph, X. Zhong, M.D. Ward,
    J. Zhang, M.J. Shelley, Soft Matter 12 (2016) 4584–4589.
date_created: 2021-02-01T13:44:00Z
date_published: 2016-05-28T00:00:00Z
date_updated: 2023-02-23T13:47:38Z
day: '28'
doi: 10.1039/c5sm03127c
extern: '1'
external_id:
  arxiv:
  - '1509.06330'
  pmid:
  - '27121100'
intvolume: '        12'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1509.06330
month: '05'
oa: 1
oa_version: Preprint
page: 4584-4589
pmid: 1
publication: Soft Matter
publication_identifier:
  eissn:
  - 1744-6848
  issn:
  - 1744-683X
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamic self-assembly of microscale rotors and swimmers
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 12
year: '2016'
...
---
_id: '9052'
abstract:
- lang: eng
  text: We describe colloidal Janus particles with metallic and dielectric faces that
    swim vigorously when illuminated by defocused optical tweezers without consuming
    any chemical fuel. Rather than wandering randomly, these optically-activated colloidal
    swimmers circulate back and forth through the beam of light, tracing out sinuous
    rosette patterns. We propose a model for this mode of light-activated transport
    that accounts for the observed behavior through a combination of self-thermophoresis
    and optically-induced torque. In the deterministic limit, this model yields trajectories
    that resemble rosette curves known as hypotrochoids.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Henrique
  full_name: Moyses, Henrique
  last_name: Moyses
- first_name: Jérémie A
  full_name: Palacci, Jérémie A
  id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
  last_name: Palacci
  orcid: 0000-0002-7253-9465
- first_name: Stefano
  full_name: Sacanna, Stefano
  last_name: Sacanna
- first_name: David G.
  full_name: Grier, David G.
  last_name: Grier
citation:
  ama: Moyses H, Palacci JA, Sacanna S, Grier DG. Trochoidal trajectories of self-propelled
    Janus particles in a diverging laser beam. <i>Soft Matter</i>. 2016;12(30):6357-6364.
    doi:<a href="https://doi.org/10.1039/c6sm01163b">10.1039/c6sm01163b</a>
  apa: Moyses, H., Palacci, J. A., Sacanna, S., &#38; Grier, D. G. (2016). Trochoidal
    trajectories of self-propelled Janus particles in a diverging laser beam. <i>Soft
    Matter</i>. Royal Society of Chemistry . <a href="https://doi.org/10.1039/c6sm01163b">https://doi.org/10.1039/c6sm01163b</a>
  chicago: Moyses, Henrique, Jérémie A Palacci, Stefano Sacanna, and David G. Grier.
    “Trochoidal Trajectories of Self-Propelled Janus Particles in a Diverging Laser
    Beam.” <i>Soft Matter</i>. Royal Society of Chemistry , 2016. <a href="https://doi.org/10.1039/c6sm01163b">https://doi.org/10.1039/c6sm01163b</a>.
  ieee: H. Moyses, J. A. Palacci, S. Sacanna, and D. G. Grier, “Trochoidal trajectories
    of self-propelled Janus particles in a diverging laser beam,” <i>Soft Matter</i>,
    vol. 12, no. 30. Royal Society of Chemistry , pp. 6357–6364, 2016.
  ista: Moyses H, Palacci JA, Sacanna S, Grier DG. 2016. Trochoidal trajectories of
    self-propelled Janus particles in a diverging laser beam. Soft Matter. 12(30),
    6357–6364.
  mla: Moyses, Henrique, et al. “Trochoidal Trajectories of Self-Propelled Janus Particles
    in a Diverging Laser Beam.” <i>Soft Matter</i>, vol. 12, no. 30, Royal Society
    of Chemistry , 2016, pp. 6357–64, doi:<a href="https://doi.org/10.1039/c6sm01163b">10.1039/c6sm01163b</a>.
  short: H. Moyses, J.A. Palacci, S. Sacanna, D.G. Grier, Soft Matter 12 (2016) 6357–6364.
date_created: 2021-02-01T13:44:15Z
date_published: 2016-08-14T00:00:00Z
date_updated: 2023-02-23T13:47:40Z
day: '14'
doi: 10.1039/c6sm01163b
extern: '1'
external_id:
  arxiv:
  - '1609.01497'
  pmid:
  - '27338294'
intvolume: '        12'
issue: '30'
keyword:
- General Chemistry
- Condensed Matter Physics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1609.01497
month: '08'
oa: 1
oa_version: Preprint
page: 6357-6364
pmid: 1
publication: Soft Matter
publication_identifier:
  eissn:
  - 1744-6848
  issn:
  - 1744-683X
publication_status: published
publisher: 'Royal Society of Chemistry '
quality_controlled: '1'
scopus_import: '1'
status: public
title: Trochoidal trajectories of self-propelled Janus particles in a diverging laser
  beam
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 12
year: '2016'
...
---
_id: '9140'
abstract:
- lang: eng
  text: 'Expected changes to future extreme precipitation remain a key uncertainty
    associated with anthropogenic climate change. Extreme precipitation has been proposed
    to scale with the precipitable water content in the atmosphere. Assuming constant
    relative humidity, this implies an increase of precipitation extremes at a rate
    of about 7% °C−1 globally as indicated by the Clausius‐Clapeyron relationship.
    Increases faster and slower than Clausius‐Clapeyron have also been reported. In
    this work, we examine the scaling between precipitation extremes and temperature
    in the present climate using simulations and measurements from surface weather
    stations collected in the frame of the HyMeX and MED‐CORDEX programs in Southern
    France. Of particular interest are departures from the Clausius‐Clapeyron thermodynamic
    expectation, their spatial and temporal distribution, and their origin. Looking
    at the scaling of precipitation extreme with temperature, two regimes emerge which
    form a hook shape: one at low temperatures (cooler than around 15°C) with rates
    of increase close to the Clausius‐Clapeyron rate and one at high temperatures
    (warmer than about 15°C) with sub‐Clausius‐Clapeyron rates and most often negative
    rates. On average, the region of focus does not seem to exhibit super Clausius‐Clapeyron
    behavior except at some stations, in contrast to earlier studies. Many factors
    can contribute to departure from Clausius‐Clapeyron scaling: time and spatial
    averaging, choice of scaling temperature (surface versus condensation level),
    and precipitation efficiency and vertical velocity in updrafts that are not necessarily
    constant with temperature. But most importantly, the dynamical contribution of
    orography to precipitation in the fall over this area during the so‐called “Cevenoles”
    events, explains the hook shape of the scaling of precipitation extremes.'
article_processing_charge: No
article_type: original
author:
- first_name: P.
  full_name: Drobinski, P.
  last_name: Drobinski
- first_name: B.
  full_name: Alonzo, B.
  last_name: Alonzo
- first_name: S.
  full_name: Bastin, S.
  last_name: Bastin
- first_name: N. Da
  full_name: Silva, N. Da
  last_name: Silva
- first_name: Caroline J
  full_name: Muller, Caroline J
  id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
  last_name: Muller
  orcid: 0000-0001-5836-5350
citation:
  ama: 'Drobinski P, Alonzo B, Bastin S, Silva ND, Muller CJ. Scaling of precipitation
    extremes with temperature in the French Mediterranean region: What explains the
    hook shape? <i>Journal of Geophysical Research: Atmospheres</i>. 2016;121(7):3100-3119.
    doi:<a href="https://doi.org/10.1002/2015jd023497">10.1002/2015jd023497</a>'
  apa: 'Drobinski, P., Alonzo, B., Bastin, S., Silva, N. D., &#38; Muller, C. J. (2016).
    Scaling of precipitation extremes with temperature in the French Mediterranean
    region: What explains the hook shape? <i>Journal of Geophysical Research: Atmospheres</i>.
    American Geophysical Union. <a href="https://doi.org/10.1002/2015jd023497">https://doi.org/10.1002/2015jd023497</a>'
  chicago: 'Drobinski, P., B. Alonzo, S. Bastin, N. Da Silva, and Caroline J Muller.
    “Scaling of Precipitation Extremes with Temperature in the French Mediterranean
    Region: What Explains the Hook Shape?” <i>Journal of Geophysical Research: Atmospheres</i>.
    American Geophysical Union, 2016. <a href="https://doi.org/10.1002/2015jd023497">https://doi.org/10.1002/2015jd023497</a>.'
  ieee: 'P. Drobinski, B. Alonzo, S. Bastin, N. D. Silva, and C. J. Muller, “Scaling
    of precipitation extremes with temperature in the French Mediterranean region:
    What explains the hook shape?,” <i>Journal of Geophysical Research: Atmospheres</i>,
    vol. 121, no. 7. American Geophysical Union, pp. 3100–3119, 2016.'
  ista: 'Drobinski P, Alonzo B, Bastin S, Silva ND, Muller CJ. 2016. Scaling of precipitation
    extremes with temperature in the French Mediterranean region: What explains the
    hook shape? Journal of Geophysical Research: Atmospheres. 121(7), 3100–3119.'
  mla: 'Drobinski, P., et al. “Scaling of Precipitation Extremes with Temperature
    in the French Mediterranean Region: What Explains the Hook Shape?” <i>Journal
    of Geophysical Research: Atmospheres</i>, vol. 121, no. 7, American Geophysical
    Union, 2016, pp. 3100–19, doi:<a href="https://doi.org/10.1002/2015jd023497">10.1002/2015jd023497</a>.'
  short: 'P. Drobinski, B. Alonzo, S. Bastin, N.D. Silva, C.J. Muller, Journal of
    Geophysical Research: Atmospheres 121 (2016) 3100–3119.'
date_created: 2021-02-15T14:21:16Z
date_published: 2016-03-16T00:00:00Z
date_updated: 2022-01-24T13:41:02Z
day: '16'
doi: 10.1002/2015jd023497
extern: '1'
intvolume: '       121'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1002/2015JD023497
month: '03'
oa: 1
oa_version: Published Version
page: 3100-3119
publication: 'Journal of Geophysical Research: Atmospheres'
publication_identifier:
  issn:
  - 2169-897X
  - 2169-8996
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
status: public
title: 'Scaling of precipitation extremes with temperature in the French Mediterranean
  region: What explains the hook shape?'
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 121
year: '2016'
...
---
_id: '7068'
abstract:
- lang: eng
  text: Electrons in materials with linear dispersion behave as massless Weyl- or
    Dirac-quasiparticles, and continue to intrigue due to their close resemblance
    to elusive ultra-relativistic particles as well as their potential for future
    electronics. Yet the experimental signatures of Weyl-fermions are often subtle
    and indirect, in particular if they coexist with conventional, massive quasiparticles.
    Here we show a pronounced anomaly in the magnetic torque of the Weyl semimetal
    NbAs upon entering the quantum limit state in high magnetic fields. The torque
    changes sign in the quantum limit, signalling a reversal of the magnetic anisotropy
    that can be directly attributed to the topological nature of the Weyl electrons.
    Our results establish that anomalous quantum limit torque measurements provide
    a direct experimental method to identify and distinguish Weyl and Dirac systems.
article_number: '12492'
article_processing_charge: No
article_type: original
author:
- first_name: Philip J. W.
  full_name: Moll, Philip J. W.
  last_name: Moll
- first_name: Andrew C.
  full_name: Potter, Andrew C.
  last_name: Potter
- first_name: Nityan L.
  full_name: Nair, Nityan L.
  last_name: Nair
- first_name: B. J.
  full_name: Ramshaw, B. J.
  last_name: Ramshaw
- first_name: Kimberly A
  full_name: Modic, Kimberly A
  id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
  last_name: Modic
  orcid: 0000-0001-9760-3147
- first_name: Scott
  full_name: Riggs, Scott
  last_name: Riggs
- first_name: Bin
  full_name: Zeng, Bin
  last_name: Zeng
- first_name: Nirmal J.
  full_name: Ghimire, Nirmal J.
  last_name: Ghimire
- first_name: Eric D.
  full_name: Bauer, Eric D.
  last_name: Bauer
- first_name: Robert
  full_name: Kealhofer, Robert
  last_name: Kealhofer
- first_name: Filip
  full_name: Ronning, Filip
  last_name: Ronning
- first_name: James G.
  full_name: Analytis, James G.
  last_name: Analytis
citation:
  ama: Moll PJW, Potter AC, Nair NL, et al. Magnetic torque anomaly in the quantum
    limit of Weyl semimetals. <i>Nature Communications</i>. 2016;7. doi:<a href="https://doi.org/10.1038/ncomms12492">10.1038/ncomms12492</a>
  apa: Moll, P. J. W., Potter, A. C., Nair, N. L., Ramshaw, B. J., Modic, K. A., Riggs,
    S., … Analytis, J. G. (2016). Magnetic torque anomaly in the quantum limit of
    Weyl semimetals. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/ncomms12492">https://doi.org/10.1038/ncomms12492</a>
  chicago: Moll, Philip J. W., Andrew C. Potter, Nityan L. Nair, B. J. Ramshaw, Kimberly
    A Modic, Scott Riggs, Bin Zeng, et al. “Magnetic Torque Anomaly in the Quantum
    Limit of Weyl Semimetals.” <i>Nature Communications</i>. Springer Nature, 2016.
    <a href="https://doi.org/10.1038/ncomms12492">https://doi.org/10.1038/ncomms12492</a>.
  ieee: P. J. W. Moll <i>et al.</i>, “Magnetic torque anomaly in the quantum limit
    of Weyl semimetals,” <i>Nature Communications</i>, vol. 7. Springer Nature, 2016.
  ista: Moll PJW, Potter AC, Nair NL, Ramshaw BJ, Modic KA, Riggs S, Zeng B, Ghimire
    NJ, Bauer ED, Kealhofer R, Ronning F, Analytis JG. 2016. Magnetic torque anomaly
    in the quantum limit of Weyl semimetals. Nature Communications. 7, 12492.
  mla: Moll, Philip J. W., et al. “Magnetic Torque Anomaly in the Quantum Limit of
    Weyl Semimetals.” <i>Nature Communications</i>, vol. 7, 12492, Springer Nature,
    2016, doi:<a href="https://doi.org/10.1038/ncomms12492">10.1038/ncomms12492</a>.
  short: P.J.W. Moll, A.C. Potter, N.L. Nair, B.J. Ramshaw, K.A. Modic, S. Riggs,
    B. Zeng, N.J. Ghimire, E.D. Bauer, R. Kealhofer, F. Ronning, J.G. Analytis, Nature
    Communications 7 (2016).
date_created: 2019-11-19T13:20:53Z
date_published: 2016-08-22T00:00:00Z
date_updated: 2021-01-12T08:11:40Z
day: '22'
ddc:
- '530'
doi: 10.1038/ncomms12492
extern: '1'
file:
- access_level: open_access
  checksum: e3272ed18d22187406b30be48a56e7b2
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-26T12:52:19Z
  date_updated: 2020-07-14T12:47:48Z
  file_id: '7114'
  file_name: 2016_NatureComm_Moll.pdf
  file_size: 663911
  relation: main_file
file_date_updated: 2020-07-14T12:47:48Z
has_accepted_license: '1'
intvolume: '         7'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Magnetic torque anomaly in the quantum limit of Weyl semimetals
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...
---
_id: '7279'
abstract:
- lang: eng
  text: Kinetics of electrochemical reactions are several orders of magnitude slower
    in solids than in liquids as a result of the much lower ion diffusivity. Yet,
    the solid state maximizes the density of redox species, which is at least two
    orders of magnitude lower in liquids because of solubility limitations. With regard
    to electrochemical energy storage devices, this leads to high-energy batteries
    with limited power and high-power supercapacitors with a well-known energy deficiency.
    For such devices the ideal system should endow the liquid state with a density
    of redox species close to the solid state. Here we report an approach based on
    biredox ionic liquids to achieve bulk-like redox density at liquid-like fast kinetics.
    The cation and anion of these biredox ionic liquids bear moieties that undergo
    very fast reversible redox reactions. As a first demonstration of their potential
    for high-capacity/high-rate charge storage, we used them in redox supercapacitors.
    These ionic liquids are able to decouple charge storage from an ion-accessible
    electrode surface, by storing significant charge in the pores of the electrodes,
    to minimize self-discharge and leakage current as a result of retaining the redox
    species in the pores, and to raise working voltage due to their wide electrochemical
    window.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Eléonore
  full_name: Mourad, Eléonore
  last_name: Mourad
- first_name: Laura
  full_name: Coustan, Laura
  last_name: Coustan
- first_name: Pierre
  full_name: Lannelongue, Pierre
  last_name: Lannelongue
- first_name: Dodzi
  full_name: Zigah, Dodzi
  last_name: Zigah
- first_name: Ahmad
  full_name: Mehdi, Ahmad
  last_name: Mehdi
- first_name: André
  full_name: Vioux, André
  last_name: Vioux
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
- first_name: Frédéric
  full_name: Favier, Frédéric
  last_name: Favier
- first_name: Olivier
  full_name: Fontaine, Olivier
  last_name: Fontaine
citation:
  ama: Mourad E, Coustan L, Lannelongue P, et al. Biredox ionic liquids with solid-like
    redox density in the liquid state for high-energy supercapacitors. <i>Nature Materials</i>.
    2016;16(4):446-453. doi:<a href="https://doi.org/10.1038/nmat4808">10.1038/nmat4808</a>
  apa: Mourad, E., Coustan, L., Lannelongue, P., Zigah, D., Mehdi, A., Vioux, A.,
    … Fontaine, O. (2016). Biredox ionic liquids with solid-like redox density in
    the liquid state for high-energy supercapacitors. <i>Nature Materials</i>. Springer
    Nature. <a href="https://doi.org/10.1038/nmat4808">https://doi.org/10.1038/nmat4808</a>
  chicago: Mourad, Eléonore, Laura Coustan, Pierre Lannelongue, Dodzi Zigah, Ahmad
    Mehdi, André Vioux, Stefan Alexander Freunberger, Frédéric Favier, and Olivier
    Fontaine. “Biredox Ionic Liquids with Solid-like Redox Density in the Liquid State
    for High-Energy Supercapacitors.” <i>Nature Materials</i>. Springer Nature, 2016.
    <a href="https://doi.org/10.1038/nmat4808">https://doi.org/10.1038/nmat4808</a>.
  ieee: E. Mourad <i>et al.</i>, “Biredox ionic liquids with solid-like redox density
    in the liquid state for high-energy supercapacitors,” <i>Nature Materials</i>,
    vol. 16, no. 4. Springer Nature, pp. 446–453, 2016.
  ista: Mourad E, Coustan L, Lannelongue P, Zigah D, Mehdi A, Vioux A, Freunberger
    SA, Favier F, Fontaine O. 2016. Biredox ionic liquids with solid-like redox density
    in the liquid state for high-energy supercapacitors. Nature Materials. 16(4),
    446–453.
  mla: Mourad, Eléonore, et al. “Biredox Ionic Liquids with Solid-like Redox Density
    in the Liquid State for High-Energy Supercapacitors.” <i>Nature Materials</i>,
    vol. 16, no. 4, Springer Nature, 2016, pp. 446–53, doi:<a href="https://doi.org/10.1038/nmat4808">10.1038/nmat4808</a>.
  short: E. Mourad, L. Coustan, P. Lannelongue, D. Zigah, A. Mehdi, A. Vioux, S.A.
    Freunberger, F. Favier, O. Fontaine, Nature Materials 16 (2016) 446–453.
date_created: 2020-01-15T07:27:54Z
date_published: 2016-11-28T00:00:00Z
date_updated: 2021-01-12T08:12:43Z
day: '28'
doi: 10.1038/nmat4808
extern: '1'
external_id:
  arxiv:
  - '1711.11518'
intvolume: '        16'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1711.11518
month: '11'
oa: 1
oa_version: Preprint
page: 446-453
publication: Nature Materials
publication_identifier:
  issn:
  - 1476-1122
  - 1476-4660
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Biredox ionic liquids with solid-like redox density in the liquid state for
  high-energy supercapacitors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2016'
...
---
_id: '7297'
abstract:
- lang: eng
  text: Redox mediators facilitate the oxidation of the highly insulating discharge
    product in metal–oxygen batteries during recharge and offer opportunities to achieve
    high reversible capacities. Now a design principle for selecting redox mediators
    that can recharge the batteries more efficiently is suggested.
article_number: '16074'
article_processing_charge: No
article_type: original
author:
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
citation:
  ama: 'Freunberger SA. Batteries: Charging ahead rationally. <i>Nature Energy</i>.
    2016;1(6). doi:<a href="https://doi.org/10.1038/nenergy.2016.74">10.1038/nenergy.2016.74</a>'
  apa: 'Freunberger, S. A. (2016). Batteries: Charging ahead rationally. <i>Nature
    Energy</i>. Springer Nature. <a href="https://doi.org/10.1038/nenergy.2016.74">https://doi.org/10.1038/nenergy.2016.74</a>'
  chicago: 'Freunberger, Stefan Alexander. “Batteries: Charging Ahead Rationally.”
    <i>Nature Energy</i>. Springer Nature, 2016. <a href="https://doi.org/10.1038/nenergy.2016.74">https://doi.org/10.1038/nenergy.2016.74</a>.'
  ieee: 'S. A. Freunberger, “Batteries: Charging ahead rationally,” <i>Nature Energy</i>,
    vol. 1, no. 6. Springer Nature, 2016.'
  ista: 'Freunberger SA. 2016. Batteries: Charging ahead rationally. Nature Energy.
    1(6), 16074.'
  mla: 'Freunberger, Stefan Alexander. “Batteries: Charging Ahead Rationally.” <i>Nature
    Energy</i>, vol. 1, no. 6, 16074, Springer Nature, 2016, doi:<a href="https://doi.org/10.1038/nenergy.2016.74">10.1038/nenergy.2016.74</a>.'
  short: S.A. Freunberger, Nature Energy 1 (2016).
date_created: 2020-01-15T12:16:40Z
date_published: 2016-05-23T00:00:00Z
date_updated: 2021-01-12T08:12:51Z
day: '23'
ddc:
- '540'
- '541'
- '547'
- '546'
doi: 10.1038/nenergy.2016.74
extern: '1'
file:
- access_level: open_access
  checksum: d90d675947262f7437b483b251918df2
  content_type: application/pdf
  creator: sfreunbe
  date_created: 2020-06-29T13:41:56Z
  date_updated: 2020-07-14T12:47:55Z
  file_id: '8047'
  file_name: N&V Freunberger final.pdf
  file_size: 197375
  relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: '         1'
issue: '6'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
publication: Nature Energy
publication_identifier:
  issn:
  - 2058-7546
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: 'Batteries: Charging ahead rationally'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2016'
...
---
_id: '7599'
abstract:
- lang: eng
  text: Normal leaf margin development is important for leaf morphogenesis and contributes
    to diverse leaf shapes in higher plants. We here show the crucial roles of an
    atypical type II phosphatidylinositol 4-kinase, PI4Kγ5, in Arabidopsis leaf margin
    development. PI4Kγ5 presents a dynamics expression pattern along with leaf development
    and a T-DNA mutant lacking PI4Kγ5, pi4kγ5–1, presents serrated leaves, which is
    resulted from the accelerated cell division and increased auxin concentration
    at serration tips. Studies revealed that PI4Kγ5 interacts with and phosphorylates
    a membrane-bound NAC transcription factor, ANAC078. Previous studies demonstrated
    that membrane-bound transcription factors regulate gene transcription by undergoing
    proteolytic process to translocate into nucleus, and ANAC078 undergoes proteolysis
    by cleaving off the transmembrane region and carboxyl terminal. Western blot analysis
    indeed showed that ANAC078 deleting of carboxyl terminal is significantly reduced
    in pi4kγ5–1, indicating that PI4Kγ5 is important for the cleavage of ANAC078.
    This is consistent with the subcellular localization observation showing that
    fluorescence by GFP-ANAC078 is detected at plasma membrane but not nucleus in
    pi4kγ5–1 mutant and that expression of ANAC078 deleting of carboxyl terminal,
    driven by PI4Kγ5 promoter, could rescue the leaf serration defects of pi4kγ5–1.
    Further analysis showed that ANAC078 suppresses the auxin synthesis by directly
    binding and regulating the expression of auxin synthesis-related genes. These
    results indicate that PI4Kγ5 interacts with ANAC078 to negatively regulate auxin
    synthesis and hence influences cell proliferation and leaf development, providing
    informative clues for the regulation of in situ auxin synthesis and cell division,
    as well as the cleavage and functional mechanism of membrane-bound transcription
    factors.
article_number: e1006252
article_processing_charge: No
article_type: original
author:
- first_name: Yong
  full_name: Tang, Yong
  last_name: Tang
- first_name: Chun-Yan
  full_name: Zhao, Chun-Yan
  last_name: Zhao
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: Hong-Wei
  full_name: Xue, Hong-Wei
  last_name: Xue
citation:
  ama: Tang Y, Zhao C-Y, Tan S, Xue H-W. Arabidopsis type II phosphatidylinositol
    4-kinase PI4Kγ5 regulates auxin biosynthesis and leaf margin development through
    interacting with membrane-bound transcription factor ANAC078. <i>PLOS Genetics</i>.
    2016;12(8). doi:<a href="https://doi.org/10.1371/journal.pgen.1006252">10.1371/journal.pgen.1006252</a>
  apa: Tang, Y., Zhao, C.-Y., Tan, S., &#38; Xue, H.-W. (2016). Arabidopsis type II
    phosphatidylinositol 4-kinase PI4Kγ5 regulates auxin biosynthesis and leaf margin
    development through interacting with membrane-bound transcription factor ANAC078.
    <i>PLOS Genetics</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pgen.1006252">https://doi.org/10.1371/journal.pgen.1006252</a>
  chicago: Tang, Yong, Chun-Yan Zhao, Shutang Tan, and Hong-Wei Xue. “Arabidopsis
    Type II Phosphatidylinositol 4-Kinase PI4Kγ5 Regulates Auxin Biosynthesis and
    Leaf Margin Development through Interacting with Membrane-Bound Transcription
    Factor ANAC078.” <i>PLOS Genetics</i>. Public Library of Science, 2016. <a href="https://doi.org/10.1371/journal.pgen.1006252">https://doi.org/10.1371/journal.pgen.1006252</a>.
  ieee: Y. Tang, C.-Y. Zhao, S. Tan, and H.-W. Xue, “Arabidopsis type II phosphatidylinositol
    4-kinase PI4Kγ5 regulates auxin biosynthesis and leaf margin development through
    interacting with membrane-bound transcription factor ANAC078,” <i>PLOS Genetics</i>,
    vol. 12, no. 8. Public Library of Science, 2016.
  ista: Tang Y, Zhao C-Y, Tan S, Xue H-W. 2016. Arabidopsis type II phosphatidylinositol
    4-kinase PI4Kγ5 regulates auxin biosynthesis and leaf margin development through
    interacting with membrane-bound transcription factor ANAC078. PLOS Genetics. 12(8),
    e1006252.
  mla: Tang, Yong, et al. “Arabidopsis Type II Phosphatidylinositol 4-Kinase PI4Kγ5
    Regulates Auxin Biosynthesis and Leaf Margin Development through Interacting with
    Membrane-Bound Transcription Factor ANAC078.” <i>PLOS Genetics</i>, vol. 12, no.
    8, e1006252, Public Library of Science, 2016, doi:<a href="https://doi.org/10.1371/journal.pgen.1006252">10.1371/journal.pgen.1006252</a>.
  short: Y. Tang, C.-Y. Zhao, S. Tan, H.-W. Xue, PLOS Genetics 12 (2016).
date_created: 2020-03-21T16:08:33Z
date_published: 2016-08-16T00:00:00Z
date_updated: 2021-01-12T08:14:25Z
day: '16'
ddc:
- '580'
doi: 10.1371/journal.pgen.1006252
extern: '1'
file:
- access_level: open_access
  checksum: ff0ab9a6bed11cda800a6e59820866a0
  content_type: application/pdf
  creator: dernst
  date_created: 2020-03-23T12:15:31Z
  date_updated: 2020-07-14T12:48:01Z
  file_id: '7612'
  file_name: 2016_PlosGenetics_Tang.PDF
  file_size: 3266119
  relation: main_file
file_date_updated: 2020-07-14T12:48:01Z
has_accepted_license: '1'
intvolume: '        12'
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: PLOS Genetics
publication_identifier:
  issn:
  - 1553-7404
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
status: public
title: Arabidopsis type II phosphatidylinositol 4-kinase PI4Kγ5 regulates auxin biosynthesis
  and leaf margin development through interacting with membrane-bound transcription
  factor ANAC078
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2016'
...
---
_id: '7737'
abstract:
- lang: eng
  text: Genome-wide association studies (GWAS) have identified thousands of genetic
    variants associated with human complex traits. However, the genes or functional
    DNA elements through which these variants exert their effects on the traits are
    often unknown. We propose a method (called SMR) that integrates summary-level
    data from GWAS with data from expression quantitative trait locus (eQTL) studies
    to identify genes whose expression levels are associated with a complex trait
    because of pleiotropy. We apply the method to five human complex traits using
    GWAS data on up to 339,224 individuals and eQTL data on 5,311 individuals, and
    we prioritize 126 genes (for example, TRAF1 and ANKRD55 for rheumatoid arthritis
    and SNX19 and NMRAL1 for schizophrenia), of which 25 genes are new candidates;
    77 genes are not the nearest annotated gene to the top associated GWAS SNP. These
    genes provide important leads to design future functional studies to understand
    the mechanism whereby DNA variation leads to complex trait variation.
article_processing_charge: No
article_type: original
author:
- first_name: Zhihong
  full_name: Zhu, Zhihong
  last_name: Zhu
- first_name: Futao
  full_name: Zhang, Futao
  last_name: Zhang
- first_name: Han
  full_name: Hu, Han
  last_name: Hu
- first_name: Andrew
  full_name: Bakshi, Andrew
  last_name: Bakshi
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
- first_name: Joseph E
  full_name: Powell, Joseph E
  last_name: Powell
- first_name: Grant W
  full_name: Montgomery, Grant W
  last_name: Montgomery
- first_name: Michael E
  full_name: Goddard, Michael E
  last_name: Goddard
- first_name: Naomi R
  full_name: Wray, Naomi R
  last_name: Wray
- first_name: Peter M
  full_name: Visscher, Peter M
  last_name: Visscher
- first_name: Jian
  full_name: Yang, Jian
  last_name: Yang
citation:
  ama: Zhu Z, Zhang F, Hu H, et al. Integration of summary data from GWAS and eQTL
    studies predicts complex trait gene targets. <i>Nature Genetics</i>. 2016;48(5):481-487.
    doi:<a href="https://doi.org/10.1038/ng.3538">10.1038/ng.3538</a>
  apa: Zhu, Z., Zhang, F., Hu, H., Bakshi, A., Robinson, M. R., Powell, J. E., … Yang,
    J. (2016). Integration of summary data from GWAS and eQTL studies predicts complex
    trait gene targets. <i>Nature Genetics</i>. Springer Nature. <a href="https://doi.org/10.1038/ng.3538">https://doi.org/10.1038/ng.3538</a>
  chicago: Zhu, Zhihong, Futao Zhang, Han Hu, Andrew Bakshi, Matthew Richard Robinson,
    Joseph E Powell, Grant W Montgomery, et al. “Integration of Summary Data from
    GWAS and EQTL Studies Predicts Complex Trait Gene Targets.” <i>Nature Genetics</i>.
    Springer Nature, 2016. <a href="https://doi.org/10.1038/ng.3538">https://doi.org/10.1038/ng.3538</a>.
  ieee: Z. Zhu <i>et al.</i>, “Integration of summary data from GWAS and eQTL studies
    predicts complex trait gene targets,” <i>Nature Genetics</i>, vol. 48, no. 5.
    Springer Nature, pp. 481–487, 2016.
  ista: Zhu Z, Zhang F, Hu H, Bakshi A, Robinson MR, Powell JE, Montgomery GW, Goddard
    ME, Wray NR, Visscher PM, Yang J. 2016. Integration of summary data from GWAS
    and eQTL studies predicts complex trait gene targets. Nature Genetics. 48(5),
    481–487.
  mla: Zhu, Zhihong, et al. “Integration of Summary Data from GWAS and EQTL Studies
    Predicts Complex Trait Gene Targets.” <i>Nature Genetics</i>, vol. 48, no. 5,
    Springer Nature, 2016, pp. 481–87, doi:<a href="https://doi.org/10.1038/ng.3538">10.1038/ng.3538</a>.
  short: Z. Zhu, F. Zhang, H. Hu, A. Bakshi, M.R. Robinson, J.E. Powell, G.W. Montgomery,
    M.E. Goddard, N.R. Wray, P.M. Visscher, J. Yang, Nature Genetics 48 (2016) 481–487.
date_created: 2020-04-30T10:50:26Z
date_published: 2016-03-28T00:00:00Z
date_updated: 2021-01-12T08:15:11Z
day: '28'
doi: 10.1038/ng.3538
extern: '1'
intvolume: '        48'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/ng.3538
month: '03'
oa: 1
oa_version: Published Version
page: 481-487
publication: Nature Genetics
publication_identifier:
  issn:
  - 1061-4036
  - 1546-1718
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Integration of summary data from GWAS and eQTL studies predicts complex trait
  gene targets
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 48
year: '2016'
...
---
_id: '786'
abstract:
- lang: eng
  text: Lock-free concurrent algorithms guarantee that some concurrent operation will
    always make progress in a finite number of steps. Yet programmers prefer to treat
    concurrent code as if it were wait-free, guaranteeing that all operations always
    make progress. Unfortunately, designing wait-free algorithms is generally a very
    complex task, and the resulting algorithms are not always efficient. Although
    obtaining efficient wait-free algorithms has been a long-time goal for the theory
    community, most nonblocking commercial code is only lock-free. This article suggests
    a simple solution to this problem.We show that for a large class of lock-free
    algorithms, under scheduling conditions that approximate those found in commercial
    hardware architectures, lock-free algorithms behave as if they are wait-free.
    In other words, programmers can continue to design simple lock-free algorithms
    instead of complex wait-free ones, and in practice, they will get wait-free progress.
    Our main contribution is a new way of analyzing a general class of lock-free algorithms
    under a stochastic scheduler. Our analysis relates the individual performance
    of processes to the global performance of the system using Markov chain lifting
    between a complex per-process chain and a simpler system progress chain. We show
    that lock-free algorithms are not only wait-free with probability 1 but that in
    fact a general subset of lock-free algorithms can be closely bounded in terms
    of the average number of steps required until an operation completes. To the best
    of our knowledge, this is the first attempt to analyze progress conditions, typically
    stated in relation to a worst-case adversary, in a stochastic model capturing
    their expected asymptotic behavior.
acknowledgement: Part of this work was performed while the first author was a postdoctoral
  associate at MIT CSAIL, where he was supported by the SNF Postdoctoral Fellows Program,
  NSF grant CCF-1217921, DoE ASCR grant ER26116/DE-SC0008923, and by grants from the
  Oracle and Intel corporations. The second author was supported in part by ISF grant
  1696/14. The third author was supported in part by NSF grants CCF-1217921, CCF-1301926,
  IIS-1447786, and CCF-1561807, and the U.S. Department of Energy under grant DE-SC0008923,
  and by equipment grants from Intel Corporation.
article_processing_charge: No
arxiv: 1
author:
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Keren
  full_name: Censor Hillel, Keren
  last_name: Censor Hillel
- first_name: Nir
  full_name: Shavit, Nir
  last_name: Shavit
citation:
  ama: Alistarh D-A, Censor Hillel K, Shavit N. Are lock free concurrent algorithms
    practically wait free . <i>Journal of the ACM</i>. 2016;63(4). doi:<a href="https://doi.org/10.1145/2903136">10.1145/2903136</a>
  apa: Alistarh, D.-A., Censor Hillel, K., &#38; Shavit, N. (2016). Are lock free
    concurrent algorithms practically wait free . <i>Journal of the ACM</i>. ACM.
    <a href="https://doi.org/10.1145/2903136">https://doi.org/10.1145/2903136</a>
  chicago: Alistarh, Dan-Adrian, Keren Censor Hillel, and Nir Shavit. “Are Lock Free
    Concurrent Algorithms Practically Wait Free .” <i>Journal of the ACM</i>. ACM,
    2016. <a href="https://doi.org/10.1145/2903136">https://doi.org/10.1145/2903136</a>.
  ieee: D.-A. Alistarh, K. Censor Hillel, and N. Shavit, “Are lock free concurrent
    algorithms practically wait free ,” <i>Journal of the ACM</i>, vol. 63, no. 4.
    ACM, 2016.
  ista: Alistarh D-A, Censor Hillel K, Shavit N. 2016. Are lock free concurrent algorithms
    practically wait free . Journal of the ACM. 63(4).
  mla: Alistarh, Dan-Adrian, et al. “Are Lock Free Concurrent Algorithms Practically
    Wait Free .” <i>Journal of the ACM</i>, vol. 63, no. 4, ACM, 2016, doi:<a href="https://doi.org/10.1145/2903136">10.1145/2903136</a>.
  short: D.-A. Alistarh, K. Censor Hillel, N. Shavit, Journal of the ACM 63 (2016).
date_created: 2018-12-11T11:48:29Z
date_published: 2016-09-01T00:00:00Z
date_updated: 2023-02-23T13:19:04Z
day: '01'
doi: 10.1145/2903136
extern: '1'
external_id:
  arxiv:
  - '1311.3200'
intvolume: '        63'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1311.3200
month: '09'
oa: 1
oa_version: Preprint
publication: Journal of the ACM
publication_status: published
publisher: ACM
publist_id: '6870'
quality_controlled: '1'
status: public
title: 'Are lock free concurrent algorithms practically wait free '
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 63
year: '2016'
...
---
_id: '8020'
abstract:
- lang: eng
  text: Balance of cortical excitation and inhibition (EI) is thought to be disrupted
    in several neuropsychiatric conditions, yet it is not clear how it is maintained
    in the healthy human brain. When EI balance is disturbed during learning and memory
    in animal models, it can be restabilized via formation of inhibitory replicas
    of newly formed excitatory connections. Here we assess evidence for such selective
    inhibitory rebalancing in humans. Using fMRI repetition suppression we measure
    newly formed cortical associations in the human brain. We show that expression
    of these associations reduces over time despite persistence in behavior, consistent
    with inhibitory rebalancing. To test this, we modulated excitation/inhibition
    balance with transcranial direct current stimulation (tDCS). Using ultra-high-field
    (7T) MRI and spectroscopy, we show that reducing GABA allows cortical associations
    to be re-expressed. This suggests that in humans associative memories are stored
    in balanced excitatory-inhibitory ensembles that lie dormant unless latent inhibitory
    connections are unmasked.
article_processing_charge: No
article_type: original
author:
- first_name: H.C.
  full_name: Barron, H.C.
  last_name: Barron
- first_name: Tim P
  full_name: Vogels, Tim P
  id: CB6FF8D2-008F-11EA-8E08-2637E6697425
  last_name: Vogels
  orcid: 0000-0003-3295-6181
- first_name: U.E.
  full_name: Emir, U.E.
  last_name: Emir
- first_name: T.R.
  full_name: Makin, T.R.
  last_name: Makin
- first_name: J.
  full_name: O’Shea, J.
  last_name: O’Shea
- first_name: S.
  full_name: Clare, S.
  last_name: Clare
- first_name: S.
  full_name: Jbabdi, S.
  last_name: Jbabdi
- first_name: R.J.
  full_name: Dolan, R.J.
  last_name: Dolan
- first_name: T.E.J.
  full_name: Behrens, T.E.J.
  last_name: Behrens
citation:
  ama: Barron HC, Vogels TP, Emir UE, et al. Unmasking latent inhibitory connections
    in human cortex to reveal dormant cortical memories. <i>Neuron</i>. 2016;90(1):191-203.
    doi:<a href="https://doi.org/10.1016/j.neuron.2016.02.031">10.1016/j.neuron.2016.02.031</a>
  apa: Barron, H. C., Vogels, T. P., Emir, U. E., Makin, T. R., O’Shea, J., Clare,
    S., … Behrens, T. E. J. (2016). Unmasking latent inhibitory connections in human
    cortex to reveal dormant cortical memories. <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/j.neuron.2016.02.031">https://doi.org/10.1016/j.neuron.2016.02.031</a>
  chicago: Barron, H.C., Tim P Vogels, U.E. Emir, T.R. Makin, J. O’Shea, S. Clare,
    S. Jbabdi, R.J. Dolan, and T.E.J. Behrens. “Unmasking Latent Inhibitory Connections
    in Human Cortex to Reveal Dormant Cortical Memories.” <i>Neuron</i>. Elsevier,
    2016. <a href="https://doi.org/10.1016/j.neuron.2016.02.031">https://doi.org/10.1016/j.neuron.2016.02.031</a>.
  ieee: H. C. Barron <i>et al.</i>, “Unmasking latent inhibitory connections in human
    cortex to reveal dormant cortical memories,” <i>Neuron</i>, vol. 90, no. 1. Elsevier,
    pp. 191–203, 2016.
  ista: Barron HC, Vogels TP, Emir UE, Makin TR, O’Shea J, Clare S, Jbabdi S, Dolan
    RJ, Behrens TEJ. 2016. Unmasking latent inhibitory connections in human cortex
    to reveal dormant cortical memories. Neuron. 90(1), 191–203.
  mla: Barron, H. C., et al. “Unmasking Latent Inhibitory Connections in Human Cortex
    to Reveal Dormant Cortical Memories.” <i>Neuron</i>, vol. 90, no. 1, Elsevier,
    2016, pp. 191–203, doi:<a href="https://doi.org/10.1016/j.neuron.2016.02.031">10.1016/j.neuron.2016.02.031</a>.
  short: H.C. Barron, T.P. Vogels, U.E. Emir, T.R. Makin, J. O’Shea, S. Clare, S.
    Jbabdi, R.J. Dolan, T.E.J. Behrens, Neuron 90 (2016) 191–203.
date_created: 2020-06-25T13:05:33Z
date_published: 2016-04-06T00:00:00Z
date_updated: 2021-01-12T08:16:34Z
day: '06'
ddc:
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doi: 10.1016/j.neuron.2016.02.031
extern: '1'
external_id:
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  - '26996082'
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publication: Neuron
publication_identifier:
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publication_status: published
publisher: Elsevier
quality_controlled: '1'
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title: Unmasking latent inhibitory connections in human cortex to reveal dormant cortical
  memories
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