---
_id: '953'
abstract:
- lang: eng
  text: 'The role of natural selection in the evolution of adaptive phenotypes has
    undergone constant probing by evolutionary biologists, employing both theoretical
    and empirical approaches. As Darwin noted, natural selection can act together
    with other processes, including random changes in the frequencies of phenotypic
    differences that are not under strong selection, and changes in the environment,
    which may reflect evolutionary changes in the organisms themselves. As understanding
    of genetics developed after 1900, the new genetic discoveries were incorporated
    into evolutionary biology. The resulting general principles were summarized by
    Julian Huxley in his 1942 book Evolution: the modern synthesis. Here, we examine
    how recent advances in genetics, developmental biology and molecular biology,
    including epigenetics, relate to today''s understanding of the evolution of adaptations.
    We illustrate how careful genetic studies have repeatedly shown that apparently
    puzzling results in a wide diversity of organisms involve processes that are consistent
    with neo-Darwinism. They do not support important roles in adaptation for processes
    such as directed mutation or the inheritance of acquired characters, and therefore
    no radical revision of our understanding of the mechanism of adaptive evolution
    is needed.'
article_number: '20162864'
article_processing_charge: No
author:
- first_name: Deborah
  full_name: Charlesworth, Deborah
  last_name: Charlesworth
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Brian
  full_name: Charlesworth, Brian
  last_name: Charlesworth
citation:
  ama: Charlesworth D, Barton NH, Charlesworth B. The sources of adaptive evolution.
    <i>Proceedings of the Royal Society of London Series B Biological Sciences</i>.
    2017;284(1855). doi:<a href="https://doi.org/10.1098/rspb.2016.2864">10.1098/rspb.2016.2864</a>
  apa: Charlesworth, D., Barton, N. H., &#38; Charlesworth, B. (2017). The sources
    of adaptive evolution. <i>Proceedings of the Royal Society of London Series B
    Biological Sciences</i>. Royal Society, The. <a href="https://doi.org/10.1098/rspb.2016.2864">https://doi.org/10.1098/rspb.2016.2864</a>
  chicago: Charlesworth, Deborah, Nicholas H Barton, and Brian Charlesworth. “The
    Sources of Adaptive Evolution.” <i>Proceedings of the Royal Society of London
    Series B Biological Sciences</i>. Royal Society, The, 2017. <a href="https://doi.org/10.1098/rspb.2016.2864">https://doi.org/10.1098/rspb.2016.2864</a>.
  ieee: D. Charlesworth, N. H. Barton, and B. Charlesworth, “The sources of adaptive
    evolution,” <i>Proceedings of the Royal Society of London Series B Biological
    Sciences</i>, vol. 284, no. 1855. Royal Society, The, 2017.
  ista: Charlesworth D, Barton NH, Charlesworth B. 2017. The sources of adaptive evolution.
    Proceedings of the Royal Society of London Series B Biological Sciences. 284(1855),
    20162864.
  mla: Charlesworth, Deborah, et al. “The Sources of Adaptive Evolution.” <i>Proceedings
    of the Royal Society of London Series B Biological Sciences</i>, vol. 284, no.
    1855, 20162864, Royal Society, The, 2017, doi:<a href="https://doi.org/10.1098/rspb.2016.2864">10.1098/rspb.2016.2864</a>.
  short: D. Charlesworth, N.H. Barton, B. Charlesworth, Proceedings of the Royal Society
    of London Series B Biological Sciences 284 (2017).
date_created: 2018-12-11T11:49:23Z
date_published: 2017-05-31T00:00:00Z
date_updated: 2023-09-22T10:01:48Z
day: '31'
department:
- _id: NiBa
doi: 10.1098/rspb.2016.2864
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  pmid:
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isi: 1
issue: '1855'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454256/
month: '05'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Proceedings of the Royal Society of London Series B Biological Sciences
publication_status: published
publisher: Royal Society, The
publist_id: '6462'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The sources of adaptive evolution
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 284
year: '2017'
...
---
_id: '954'
abstract:
- lang: eng
  text: Understanding the relation between genotype and phenotype remains a major
    challenge. The difficulty of predicting individual mutation effects, and particularly
    the interactions between them, has prevented the development of a comprehensive
    theory that links genotypic changes to their phenotypic effects. We show that
    a general thermodynamic framework for gene regulation, based on a biophysical
    understanding of protein-DNA binding, accurately predicts the sign of epistasis
    in a canonical cis-regulatory element consisting of overlapping RNA polymerase
    and repressor binding sites. Sign and magnitude of individual mutation effects
    are sufficient to predict the sign of epistasis and its environmental dependence.
    Thus, the thermodynamic model offers the correct null prediction for epistasis
    between mutations across DNA-binding sites. Our results indicate that a predictive
    theory for the effects of cis-regulatory mutations is possible from first principles,
    as long as the essential molecular mechanisms and the constraints these impose
    on a biological system are accounted for.
article_number: e25192
article_processing_charge: Yes
author:
- first_name: Mato
  full_name: Lagator, Mato
  id: 345D25EC-F248-11E8-B48F-1D18A9856A87
  last_name: Lagator
- first_name: Tiago
  full_name: Paixao, Tiago
  id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
  last_name: Paixao
  orcid: 0000-0003-2361-3953
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
citation:
  ama: Lagator M, Paixao T, Barton NH, Bollback JP, Guet CC. On the mechanistic nature
    of epistasis in a canonical cis-regulatory element. <i>eLife</i>. 2017;6. doi:<a
    href="https://doi.org/10.7554/eLife.25192">10.7554/eLife.25192</a>
  apa: Lagator, M., Paixao, T., Barton, N. H., Bollback, J. P., &#38; Guet, C. C.
    (2017). On the mechanistic nature of epistasis in a canonical cis-regulatory element.
    <i>ELife</i>. eLife Sciences Publications. <a href="https://doi.org/10.7554/eLife.25192">https://doi.org/10.7554/eLife.25192</a>
  chicago: Lagator, Mato, Tiago Paixao, Nicholas H Barton, Jonathan P Bollback, and
    Calin C Guet. “On the Mechanistic Nature of Epistasis in a Canonical Cis-Regulatory
    Element.” <i>ELife</i>. eLife Sciences Publications, 2017. <a href="https://doi.org/10.7554/eLife.25192">https://doi.org/10.7554/eLife.25192</a>.
  ieee: M. Lagator, T. Paixao, N. H. Barton, J. P. Bollback, and C. C. Guet, “On the
    mechanistic nature of epistasis in a canonical cis-regulatory element,” <i>eLife</i>,
    vol. 6. eLife Sciences Publications, 2017.
  ista: Lagator M, Paixao T, Barton NH, Bollback JP, Guet CC. 2017. On the mechanistic
    nature of epistasis in a canonical cis-regulatory element. eLife. 6, e25192.
  mla: Lagator, Mato, et al. “On the Mechanistic Nature of Epistasis in a Canonical
    Cis-Regulatory Element.” <i>ELife</i>, vol. 6, e25192, eLife Sciences Publications,
    2017, doi:<a href="https://doi.org/10.7554/eLife.25192">10.7554/eLife.25192</a>.
  short: M. Lagator, T. Paixao, N.H. Barton, J.P. Bollback, C.C. Guet, ELife 6 (2017).
date_created: 2018-12-11T11:49:23Z
date_published: 2017-05-18T00:00:00Z
date_updated: 2023-09-22T10:01:17Z
day: '18'
ddc:
- '576'
department:
- _id: CaGu
- _id: NiBa
- _id: JoBo
doi: 10.7554/eLife.25192
ec_funded: 1
external_id:
  isi:
  - '000404024800001'
file:
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  creator: system
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file_date_updated: 2020-07-14T12:48:16Z
has_accepted_license: '1'
intvolume: '         6'
isi: 1
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 25B1EC9E-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '618091'
  name: Speed of Adaptation in Population Genetics and Evolutionary Computation
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 2578D616-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '648440'
  name: Selective Barriers to Horizontal Gene Transfer
publication: eLife
publication_identifier:
  issn:
  - 2050084X
publication_status: published
publisher: eLife Sciences Publications
publist_id: '6460'
pubrep_id: '841'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the mechanistic nature of epistasis in a canonical cis-regulatory element
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 6
year: '2017'
...
---
_id: '955'
abstract:
- lang: eng
  text: 'Gene expression is controlled by networks of regulatory proteins that interact
    specifically with external signals and DNA regulatory sequences. These interactions
    force the network components to co-evolve so as to continually maintain function.
    Yet, existing models of evolution mostly focus on isolated genetic elements. In
    contrast, we study the essential process by which regulatory networks grow: the
    duplication and subsequent specialization of network components. We synthesize
    a biophysical model of molecular interactions with the evolutionary framework
    to find the conditions and pathways by which new regulatory functions emerge.
    We show that specialization of new network components is usually slow, but can
    be drastically accelerated in the presence of regulatory crosstalk and mutations
    that promote promiscuous interactions between network components.'
article_number: '216'
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Tamar
  full_name: Friedlander, Tamar
  id: 36A5845C-F248-11E8-B48F-1D18A9856A87
  last_name: Friedlander
- first_name: Roshan
  full_name: Prizak, Roshan
  id: 4456104E-F248-11E8-B48F-1D18A9856A87
  last_name: Prizak
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
citation:
  ama: Friedlander T, Prizak R, Barton NH, Tkačik G. Evolution of new regulatory functions
    on biophysically realistic fitness landscapes. <i>Nature Communications</i>. 2017;8(1).
    doi:<a href="https://doi.org/10.1038/s41467-017-00238-8">10.1038/s41467-017-00238-8</a>
  apa: Friedlander, T., Prizak, R., Barton, N. H., &#38; Tkačik, G. (2017). Evolution
    of new regulatory functions on biophysically realistic fitness landscapes. <i>Nature
    Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/s41467-017-00238-8">https://doi.org/10.1038/s41467-017-00238-8</a>
  chicago: Friedlander, Tamar, Roshan Prizak, Nicholas H Barton, and Gašper Tkačik.
    “Evolution of New Regulatory Functions on Biophysically Realistic Fitness Landscapes.”
    <i>Nature Communications</i>. Nature Publishing Group, 2017. <a href="https://doi.org/10.1038/s41467-017-00238-8">https://doi.org/10.1038/s41467-017-00238-8</a>.
  ieee: T. Friedlander, R. Prizak, N. H. Barton, and G. Tkačik, “Evolution of new
    regulatory functions on biophysically realistic fitness landscapes,” <i>Nature
    Communications</i>, vol. 8, no. 1. Nature Publishing Group, 2017.
  ista: Friedlander T, Prizak R, Barton NH, Tkačik G. 2017. Evolution of new regulatory
    functions on biophysically realistic fitness landscapes. Nature Communications.
    8(1), 216.
  mla: Friedlander, Tamar, et al. “Evolution of New Regulatory Functions on Biophysically
    Realistic Fitness Landscapes.” <i>Nature Communications</i>, vol. 8, no. 1, 216,
    Nature Publishing Group, 2017, doi:<a href="https://doi.org/10.1038/s41467-017-00238-8">10.1038/s41467-017-00238-8</a>.
  short: T. Friedlander, R. Prizak, N.H. Barton, G. Tkačik, Nature Communications
    8 (2017).
date_created: 2018-12-11T11:49:23Z
date_published: 2017-08-09T00:00:00Z
date_updated: 2025-05-28T11:42:50Z
day: '09'
ddc:
- '539'
- '576'
department:
- _id: GaTk
- _id: NiBa
doi: 10.1038/s41467-017-00238-8
ec_funded: 1
external_id:
  isi:
  - '000407198800005'
file:
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file_date_updated: 2020-07-14T12:48:16Z
has_accepted_license: '1'
intvolume: '         8'
isi: 1
issue: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
- _id: 254E9036-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28844-B27
  name: Biophysics of information processing in gene regulation
publication: Nature Communications
publication_identifier:
  issn:
  - '20411723'
publication_status: published
publisher: Nature Publishing Group
publist_id: '6459'
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quality_controlled: '1'
related_material:
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  - id: '6071'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Evolution of new regulatory functions on biophysically realistic fitness landscapes
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8
year: '2017'
...
---
_id: '956'
abstract:
- lang: eng
  text: We study a class of ergodic quantum Markov semigroups on finite-dimensional
    unital C⁎-algebras. These semigroups have a unique stationary state σ, and we
    are concerned with those that satisfy a quantum detailed balance condition with
    respect to σ. We show that the evolution on the set of states that is given by
    such a quantum Markov semigroup is gradient flow for the relative entropy with
    respect to σ in a particular Riemannian metric on the set of states. This metric
    is a non-commutative analog of the 2-Wasserstein metric, and in several interesting
    cases we are able to show, in analogy with work of Otto on gradient flows with
    respect to the classical 2-Wasserstein metric, that the relative entropy is strictly
    and uniformly convex with respect to the Riemannian metric introduced here. As
    a consequence, we obtain a number of new inequalities for the decay of relative
    entropy for ergodic quantum Markov semigroups with detailed balance.
article_processing_charge: No
author:
- first_name: Eric
  full_name: Carlen, Eric
  last_name: Carlen
- first_name: Jan
  full_name: Maas, Jan
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
citation:
  ama: Carlen E, Maas J. Gradient flow and entropy inequalities for quantum Markov
    semigroups with detailed balance. <i>Journal of Functional Analysis</i>. 2017;273(5):1810-1869.
    doi:<a href="https://doi.org/10.1016/j.jfa.2017.05.003">10.1016/j.jfa.2017.05.003</a>
  apa: Carlen, E., &#38; Maas, J. (2017). Gradient flow and entropy inequalities for
    quantum Markov semigroups with detailed balance. <i>Journal of Functional Analysis</i>.
    Academic Press. <a href="https://doi.org/10.1016/j.jfa.2017.05.003">https://doi.org/10.1016/j.jfa.2017.05.003</a>
  chicago: Carlen, Eric, and Jan Maas. “Gradient Flow and Entropy Inequalities for
    Quantum Markov Semigroups with Detailed Balance.” <i>Journal of Functional Analysis</i>.
    Academic Press, 2017. <a href="https://doi.org/10.1016/j.jfa.2017.05.003">https://doi.org/10.1016/j.jfa.2017.05.003</a>.
  ieee: E. Carlen and J. Maas, “Gradient flow and entropy inequalities for quantum
    Markov semigroups with detailed balance,” <i>Journal of Functional Analysis</i>,
    vol. 273, no. 5. Academic Press, pp. 1810–1869, 2017.
  ista: Carlen E, Maas J. 2017. Gradient flow and entropy inequalities for quantum
    Markov semigroups with detailed balance. Journal of Functional Analysis. 273(5),
    1810–1869.
  mla: Carlen, Eric, and Jan Maas. “Gradient Flow and Entropy Inequalities for Quantum
    Markov Semigroups with Detailed Balance.” <i>Journal of Functional Analysis</i>,
    vol. 273, no. 5, Academic Press, 2017, pp. 1810–69, doi:<a href="https://doi.org/10.1016/j.jfa.2017.05.003">10.1016/j.jfa.2017.05.003</a>.
  short: E. Carlen, J. Maas, Journal of Functional Analysis 273 (2017) 1810–1869.
date_created: 2018-12-11T11:49:24Z
date_published: 2017-09-01T00:00:00Z
date_updated: 2023-09-22T10:00:18Z
day: '01'
department:
- _id: JaMa
doi: 10.1016/j.jfa.2017.05.003
external_id:
  isi:
  - '000406082300005'
intvolume: '       273'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1609.01254
month: '09'
oa: 1
oa_version: Submitted Version
page: 1810 - 1869
publication: Journal of Functional Analysis
publication_identifier:
  issn:
  - '00221236'
publication_status: published
publisher: Academic Press
publist_id: '6452'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gradient flow and entropy inequalities for quantum Markov semigroups with detailed
  balance
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 273
year: '2017'
...
---
_id: '9574'
abstract:
- lang: eng
  text: 'Consider the sum X(ξ)=∑ni=1aiξi, where a=(ai)ni=1 is a sequence of non-zero
    reals and ξ=(ξi)ni=1 is a sequence of i.i.d. Rademacher random variables (that
    is, Pr[ξi=1]=Pr[ξi=−1]=1/2). The classical Littlewood-Offord problem asks for
    the best possible upper bound on the concentration probabilities Pr[X=x]. In this
    paper we study a resilience version of the Littlewood-Offord problem: how many
    of the ξi is an adversary typically allowed to change without being able to force
    concentration on a particular value? We solve this problem asymptotically, and
    present a few interesting open problems.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Afonso S.
  full_name: Bandeira, Afonso S.
  last_name: Bandeira
- first_name: Asaf
  full_name: Ferber, Asaf
  last_name: Ferber
- first_name: Matthew Alan
  full_name: Kwan, Matthew Alan
  id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
  last_name: Kwan
  orcid: 0000-0002-4003-7567
citation:
  ama: Bandeira AS, Ferber A, Kwan MA. Resilience for the Littlewood-Offord problem.
    <i>Electronic Notes in Discrete Mathematics</i>. 2017;61:93-99. doi:<a href="https://doi.org/10.1016/j.endm.2017.06.025">10.1016/j.endm.2017.06.025</a>
  apa: Bandeira, A. S., Ferber, A., &#38; Kwan, M. A. (2017). Resilience for the Littlewood-Offord
    problem. <i>Electronic Notes in Discrete Mathematics</i>. Elsevier. <a href="https://doi.org/10.1016/j.endm.2017.06.025">https://doi.org/10.1016/j.endm.2017.06.025</a>
  chicago: Bandeira, Afonso S., Asaf Ferber, and Matthew Alan Kwan. “Resilience for
    the Littlewood-Offord Problem.” <i>Electronic Notes in Discrete Mathematics</i>.
    Elsevier, 2017. <a href="https://doi.org/10.1016/j.endm.2017.06.025">https://doi.org/10.1016/j.endm.2017.06.025</a>.
  ieee: A. S. Bandeira, A. Ferber, and M. A. Kwan, “Resilience for the Littlewood-Offord
    problem,” <i>Electronic Notes in Discrete Mathematics</i>, vol. 61. Elsevier,
    pp. 93–99, 2017.
  ista: Bandeira AS, Ferber A, Kwan MA. 2017. Resilience for the Littlewood-Offord
    problem. Electronic Notes in Discrete Mathematics. 61, 93–99.
  mla: Bandeira, Afonso S., et al. “Resilience for the Littlewood-Offord Problem.”
    <i>Electronic Notes in Discrete Mathematics</i>, vol. 61, Elsevier, 2017, pp.
    93–99, doi:<a href="https://doi.org/10.1016/j.endm.2017.06.025">10.1016/j.endm.2017.06.025</a>.
  short: A.S. Bandeira, A. Ferber, M.A. Kwan, Electronic Notes in Discrete Mathematics
    61 (2017) 93–99.
date_created: 2021-06-21T06:31:10Z
date_published: 2017-08-01T00:00:00Z
date_updated: 2023-02-23T14:01:26Z
day: '01'
doi: 10.1016/j.endm.2017.06.025
extern: '1'
external_id:
  arxiv:
  - '1609.08136'
intvolume: '        61'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1609.08136
month: '08'
oa: 1
oa_version: Preprint
page: 93-99
publication: Electronic Notes in Discrete Mathematics
publication_identifier:
  issn:
  - 1571-0653
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Resilience for the Littlewood-Offord problem
type: journal_article
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 61
year: '2017'
...
---
_id: '9588'
abstract:
- lang: eng
  text: 'Consider the sum  X(ξ)=∑ni=1aiξi , where  a=(ai)ni=1  is a sequence of non-zero
    reals and  ξ=(ξi)ni=1  is a sequence of i.i.d. Rademacher random variables (that
    is,  Pr[ξi=1]=Pr[ξi=−1]=1/2 ). The classical Littlewood-Offord problem asks for
    the best possible upper bound on the concentration probabilities  Pr[X=x] . In
    this paper we study a resilience version of the Littlewood-Offord problem: how
    many of the  ξi  is an adversary typically allowed to change without being able
    to force concentration on a particular value? We solve this problem asymptotically,
    and present a few interesting open problems.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Afonso S.
  full_name: Bandeira, Afonso S.
  last_name: Bandeira
- first_name: Asaf
  full_name: Ferber, Asaf
  last_name: Ferber
- first_name: Matthew Alan
  full_name: Kwan, Matthew Alan
  id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
  last_name: Kwan
  orcid: 0000-0002-4003-7567
citation:
  ama: Bandeira AS, Ferber A, Kwan MA. Resilience for the Littlewood–Offord problem.
    <i>Advances in Mathematics</i>. 2017;319:292-312. doi:<a href="https://doi.org/10.1016/j.aim.2017.08.031">10.1016/j.aim.2017.08.031</a>
  apa: Bandeira, A. S., Ferber, A., &#38; Kwan, M. A. (2017). Resilience for the Littlewood–Offord
    problem. <i>Advances in Mathematics</i>. Elsevier. <a href="https://doi.org/10.1016/j.aim.2017.08.031">https://doi.org/10.1016/j.aim.2017.08.031</a>
  chicago: Bandeira, Afonso S., Asaf Ferber, and Matthew Alan Kwan. “Resilience for
    the Littlewood–Offord Problem.” <i>Advances in Mathematics</i>. Elsevier, 2017.
    <a href="https://doi.org/10.1016/j.aim.2017.08.031">https://doi.org/10.1016/j.aim.2017.08.031</a>.
  ieee: A. S. Bandeira, A. Ferber, and M. A. Kwan, “Resilience for the Littlewood–Offord
    problem,” <i>Advances in Mathematics</i>, vol. 319. Elsevier, pp. 292–312, 2017.
  ista: Bandeira AS, Ferber A, Kwan MA. 2017. Resilience for the Littlewood–Offord
    problem. Advances in Mathematics. 319, 292–312.
  mla: Bandeira, Afonso S., et al. “Resilience for the Littlewood–Offord Problem.”
    <i>Advances in Mathematics</i>, vol. 319, Elsevier, 2017, pp. 292–312, doi:<a
    href="https://doi.org/10.1016/j.aim.2017.08.031">10.1016/j.aim.2017.08.031</a>.
  short: A.S. Bandeira, A. Ferber, M.A. Kwan, Advances in Mathematics 319 (2017) 292–312.
date_created: 2021-06-22T11:51:27Z
date_published: 2017-10-15T00:00:00Z
date_updated: 2023-02-23T14:01:57Z
day: '15'
doi: 10.1016/j.aim.2017.08.031
extern: '1'
external_id:
  arxiv:
  - '1609.08136'
intvolume: '       319'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1609.08136
month: '10'
oa: 1
oa_version: Preprint
page: 292-312
publication: Advances in Mathematics
publication_identifier:
  issn:
  - 0001-8708
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Resilience for the Littlewood–Offord problem
type: journal_article
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 319
year: '2017'
...
---
_id: '9589'
abstract:
- lang: eng
  text: We give an asymptotic expression for the expected number of spanning trees
    in a random graph with a given degree sequence , provided that the number of edges
    is at least , where  is the maximum degree. A key part of our argument involves
    establishing a concentration result for a certain family of functions over random
    trees with given degrees, using Prüfer codes.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Catherine
  full_name: Greenhill, Catherine
  last_name: Greenhill
- first_name: Mikhail
  full_name: Isaev, Mikhail
  last_name: Isaev
- first_name: Matthew Alan
  full_name: Kwan, Matthew Alan
  id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
  last_name: Kwan
  orcid: 0000-0002-4003-7567
- first_name: Brendan D.
  full_name: McKay, Brendan D.
  last_name: McKay
citation:
  ama: Greenhill C, Isaev M, Kwan MA, McKay BD. The average number of spanning trees
    in sparse graphs with given degrees. <i>European Journal of Combinatorics</i>.
    2017;63:6-25. doi:<a href="https://doi.org/10.1016/j.ejc.2017.02.003">10.1016/j.ejc.2017.02.003</a>
  apa: Greenhill, C., Isaev, M., Kwan, M. A., &#38; McKay, B. D. (2017). The average
    number of spanning trees in sparse graphs with given degrees. <i>European Journal
    of Combinatorics</i>. Elsevier. <a href="https://doi.org/10.1016/j.ejc.2017.02.003">https://doi.org/10.1016/j.ejc.2017.02.003</a>
  chicago: Greenhill, Catherine, Mikhail Isaev, Matthew Alan Kwan, and Brendan D.
    McKay. “The Average Number of Spanning Trees in Sparse Graphs with given Degrees.”
    <i>European Journal of Combinatorics</i>. Elsevier, 2017. <a href="https://doi.org/10.1016/j.ejc.2017.02.003">https://doi.org/10.1016/j.ejc.2017.02.003</a>.
  ieee: C. Greenhill, M. Isaev, M. A. Kwan, and B. D. McKay, “The average number of
    spanning trees in sparse graphs with given degrees,” <i>European Journal of Combinatorics</i>,
    vol. 63. Elsevier, pp. 6–25, 2017.
  ista: Greenhill C, Isaev M, Kwan MA, McKay BD. 2017. The average number of spanning
    trees in sparse graphs with given degrees. European Journal of Combinatorics.
    63, 6–25.
  mla: Greenhill, Catherine, et al. “The Average Number of Spanning Trees in Sparse
    Graphs with given Degrees.” <i>European Journal of Combinatorics</i>, vol. 63,
    Elsevier, 2017, pp. 6–25, doi:<a href="https://doi.org/10.1016/j.ejc.2017.02.003">10.1016/j.ejc.2017.02.003</a>.
  short: C. Greenhill, M. Isaev, M.A. Kwan, B.D. McKay, European Journal of Combinatorics
    63 (2017) 6–25.
date_created: 2021-06-22T12:18:59Z
date_published: 2017-06-01T00:00:00Z
date_updated: 2023-02-23T14:02:00Z
day: '01'
doi: 10.1016/j.ejc.2017.02.003
extern: '1'
external_id:
  arxiv:
  - '1606.01586'
intvolume: '        63'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.ejc.2017.02.003
month: '06'
oa: 1
oa_version: Published Version
page: 6-25
publication: European Journal of Combinatorics
publication_identifier:
  issn:
  - 0195-6698
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: The average number of spanning trees in sparse graphs with given degrees
type: journal_article
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 63
year: '2017'
...
---
_id: '959'
abstract:
- lang: eng
  text: In this work it is shown that scale-free tails in metabolic flux distributions
    inferred in stationary models are an artifact due to reactions involved in thermodynamically
    unfeasible cycles, unbounded by physical constraints and in principle able to
    perform work without expenditure of free energy. After implementing thermodynamic
    constraints by removing such loops, metabolic flux distributions scale meaningfully
    with the physical limiting factors, acquiring in turn a richer multimodal structure
    potentially leading to symmetry breaking while optimizing for objective functions.
article_processing_charge: No
author:
- first_name: Daniele
  full_name: De Martino, Daniele
  id: 3FF5848A-F248-11E8-B48F-1D18A9856A87
  last_name: De Martino
  orcid: 0000-0002-5214-4706
citation:
  ama: De Martino D. Scales and multimodal flux distributions in stationary metabolic
    network models via thermodynamics. <i> Physical Review E Statistical Nonlinear
    and Soft Matter Physics </i>. 2017;95(6):062419. doi:<a href="https://doi.org/10.1103/PhysRevE.95.062419">10.1103/PhysRevE.95.062419</a>
  apa: De Martino, D. (2017). Scales and multimodal flux distributions in stationary
    metabolic network models via thermodynamics. <i> Physical Review E Statistical
    Nonlinear and Soft Matter Physics </i>. American Institute of Physics. <a href="https://doi.org/10.1103/PhysRevE.95.062419">https://doi.org/10.1103/PhysRevE.95.062419</a>
  chicago: De Martino, Daniele. “Scales and Multimodal Flux Distributions in Stationary
    Metabolic Network Models via Thermodynamics.” <i> Physical Review E Statistical
    Nonlinear and Soft Matter Physics </i>. American Institute of Physics, 2017. <a
    href="https://doi.org/10.1103/PhysRevE.95.062419">https://doi.org/10.1103/PhysRevE.95.062419</a>.
  ieee: D. De Martino, “Scales and multimodal flux distributions in stationary metabolic
    network models via thermodynamics,” <i> Physical Review E Statistical Nonlinear
    and Soft Matter Physics </i>, vol. 95, no. 6. American Institute of Physics, p.
    062419, 2017.
  ista: De Martino D. 2017. Scales and multimodal flux distributions in stationary
    metabolic network models via thermodynamics.  Physical Review E Statistical Nonlinear
    and Soft Matter Physics . 95(6), 062419.
  mla: De Martino, Daniele. “Scales and Multimodal Flux Distributions in Stationary
    Metabolic Network Models via Thermodynamics.” <i> Physical Review E Statistical
    Nonlinear and Soft Matter Physics </i>, vol. 95, no. 6, American Institute of
    Physics, 2017, p. 062419, doi:<a href="https://doi.org/10.1103/PhysRevE.95.062419">10.1103/PhysRevE.95.062419</a>.
  short: D. De Martino,  Physical Review E Statistical Nonlinear and Soft Matter Physics  95
    (2017) 062419.
date_created: 2018-12-11T11:49:25Z
date_published: 2017-06-28T00:00:00Z
date_updated: 2023-09-22T09:59:01Z
day: '28'
department:
- _id: GaTk
doi: 10.1103/PhysRevE.95.062419
ec_funded: 1
external_id:
  isi:
  - '000404546400004'
intvolume: '        95'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/pdf/1703.00853.pdf
month: '06'
oa: 1
oa_version: Submitted Version
page: '062419'
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: ' Physical Review E Statistical Nonlinear and Soft Matter Physics '
publication_identifier:
  issn:
  - '24700045'
publication_status: published
publisher: American Institute of Physics
publist_id: '6446'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Scales and multimodal flux distributions in stationary metabolic network models
  via thermodynamics
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 95
year: '2017'
...
---
_id: '9590'
abstract:
- lang: eng
  text: We show that for any fixed dense graph G and bounded-degree tree T on the
    same number of vertices, a modest random perturbation of G will typically contain
    a copy of T . This combines the viewpoints of the well-studied problems of embedding
    trees into fixed dense graphs and into random graphs, and extends a sizeable body
    of existing research on randomly perturbed graphs. Specifically, we show that
    there is c=c(α,Δ) such that if G is an n-vertex graph with minimum degree at least
    αn, and T is an n-vertex tree with maximum degree at most Δ , then if we add cn
    uniformly random edges to G, the resulting graph will contain T asymptotically
    almost surely (as n→∞ ). Our proof uses a lemma concerning the decomposition of
    a dense graph into super-regular pairs of comparable sizes, which may be of independent
    interest.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Krivelevich, Michael
  last_name: Krivelevich
- first_name: Matthew Alan
  full_name: Kwan, Matthew Alan
  id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
  last_name: Kwan
  orcid: 0000-0002-4003-7567
- first_name: Benny
  full_name: Sudakov, Benny
  last_name: Sudakov
citation:
  ama: Krivelevich M, Kwan MA, Sudakov B. Bounded-degree spanning trees in randomly
    perturbed graphs. <i>SIAM Journal on Discrete Mathematics</i>. 2017;31(1):155-171.
    doi:<a href="https://doi.org/10.1137/15m1032910">10.1137/15m1032910</a>
  apa: Krivelevich, M., Kwan, M. A., &#38; Sudakov, B. (2017). Bounded-degree spanning
    trees in randomly perturbed graphs. <i>SIAM Journal on Discrete Mathematics</i>.
    Society for Industrial &#38; Applied Mathematics. <a href="https://doi.org/10.1137/15m1032910">https://doi.org/10.1137/15m1032910</a>
  chicago: Krivelevich, Michael, Matthew Alan Kwan, and Benny Sudakov. “Bounded-Degree
    Spanning Trees in Randomly Perturbed Graphs.” <i>SIAM Journal on Discrete Mathematics</i>.
    Society for Industrial &#38; Applied Mathematics, 2017. <a href="https://doi.org/10.1137/15m1032910">https://doi.org/10.1137/15m1032910</a>.
  ieee: M. Krivelevich, M. A. Kwan, and B. Sudakov, “Bounded-degree spanning trees
    in randomly perturbed graphs,” <i>SIAM Journal on Discrete Mathematics</i>, vol.
    31, no. 1. Society for Industrial &#38; Applied Mathematics, pp. 155–171, 2017.
  ista: Krivelevich M, Kwan MA, Sudakov B. 2017. Bounded-degree spanning trees in
    randomly perturbed graphs. SIAM Journal on Discrete Mathematics. 31(1), 155–171.
  mla: Krivelevich, Michael, et al. “Bounded-Degree Spanning Trees in Randomly Perturbed
    Graphs.” <i>SIAM Journal on Discrete Mathematics</i>, vol. 31, no. 1, Society
    for Industrial &#38; Applied Mathematics, 2017, pp. 155–71, doi:<a href="https://doi.org/10.1137/15m1032910">10.1137/15m1032910</a>.
  short: M. Krivelevich, M.A. Kwan, B. Sudakov, SIAM Journal on Discrete Mathematics
    31 (2017) 155–171.
date_created: 2021-06-22T12:26:25Z
date_published: 2017-01-12T00:00:00Z
date_updated: 2023-02-23T14:02:05Z
day: '12'
doi: 10.1137/15m1032910
extern: '1'
external_id:
  arxiv:
  - '1507.07960'
intvolume: '        31'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1507.07960
month: '01'
oa: 1
oa_version: Preprint
page: 155-171
publication: SIAM Journal on Discrete Mathematics
publication_identifier:
  eissn:
  - 1095-7146
  issn:
  - 0895-4801
publication_status: published
publisher: Society for Industrial & Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bounded-degree spanning trees in randomly perturbed graphs
type: journal_article
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 31
year: '2017'
...
---
_id: '960'
abstract:
- lang: eng
  text: The human cerebral cortex is the seat of our cognitive abilities and composed
    of an extraordinary number of neurons, organized in six distinct layers. The establishment
    of specific morphological and physiological features in individual neurons needs
    to be regulated with high precision. Impairments in the sequential developmental
    programs instructing corticogenesis lead to alterations in the cortical cytoarchitecture
    which is thought to represent the major underlying cause for several neurological
    disorders including neurodevelopmental and psychiatric diseases. In this review
    we discuss the role of cell polarity at sequential stages during cortex development.
    We first provide an overview of morphological cell polarity features in cortical
    neural stem cells and newly-born postmitotic neurons. We then synthesize a conceptual
    molecular and biochemical framework how cell polarity is established at the cellular
    level through a break in symmetry in nascent cortical projection neurons. Lastly
    we provide a perspective how the molecular mechanisms applying to single cells
    could be probed and integrated in an in vivo and tissue-wide context.
article_number: '176'
article_processing_charge: Yes
author:
- first_name: Andi H
  full_name: Hansen, Andi H
  id: 38853E16-F248-11E8-B48F-1D18A9856A87
  last_name: Hansen
- first_name: Christian F
  full_name: Düllberg, Christian F
  id: 459064DC-F248-11E8-B48F-1D18A9856A87
  last_name: Düllberg
  orcid: 0000-0001-6335-9748
- first_name: Christine
  full_name: Mieck, Christine
  id: 34CAE85C-F248-11E8-B48F-1D18A9856A87
  last_name: Mieck
  orcid: 0000-0003-1919-7416
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
citation:
  ama: Hansen AH, Düllberg CF, Mieck C, Loose M, Hippenmeyer S. Cell polarity in cerebral
    cortex development - cellular architecture shaped by biochemical networks. <i>Frontiers
    in Cellular Neuroscience</i>. 2017;11. doi:<a href="https://doi.org/10.3389/fncel.2017.00176">10.3389/fncel.2017.00176</a>
  apa: Hansen, A. H., Düllberg, C. F., Mieck, C., Loose, M., &#38; Hippenmeyer, S.
    (2017). Cell polarity in cerebral cortex development - cellular architecture shaped
    by biochemical networks. <i>Frontiers in Cellular Neuroscience</i>. Frontiers
    Research Foundation. <a href="https://doi.org/10.3389/fncel.2017.00176">https://doi.org/10.3389/fncel.2017.00176</a>
  chicago: Hansen, Andi H, Christian F Düllberg, Christine Mieck, Martin Loose, and
    Simon Hippenmeyer. “Cell Polarity in Cerebral Cortex Development - Cellular Architecture
    Shaped by Biochemical Networks.” <i>Frontiers in Cellular Neuroscience</i>. Frontiers
    Research Foundation, 2017. <a href="https://doi.org/10.3389/fncel.2017.00176">https://doi.org/10.3389/fncel.2017.00176</a>.
  ieee: A. H. Hansen, C. F. Düllberg, C. Mieck, M. Loose, and S. Hippenmeyer, “Cell
    polarity in cerebral cortex development - cellular architecture shaped by biochemical
    networks,” <i>Frontiers in Cellular Neuroscience</i>, vol. 11. Frontiers Research
    Foundation, 2017.
  ista: Hansen AH, Düllberg CF, Mieck C, Loose M, Hippenmeyer S. 2017. Cell polarity
    in cerebral cortex development - cellular architecture shaped by biochemical networks.
    Frontiers in Cellular Neuroscience. 11, 176.
  mla: Hansen, Andi H., et al. “Cell Polarity in Cerebral Cortex Development - Cellular
    Architecture Shaped by Biochemical Networks.” <i>Frontiers in Cellular Neuroscience</i>,
    vol. 11, 176, Frontiers Research Foundation, 2017, doi:<a href="https://doi.org/10.3389/fncel.2017.00176">10.3389/fncel.2017.00176</a>.
  short: A.H. Hansen, C.F. Düllberg, C. Mieck, M. Loose, S. Hippenmeyer, Frontiers
    in Cellular Neuroscience 11 (2017).
date_created: 2018-12-11T11:49:25Z
date_published: 2017-06-28T00:00:00Z
date_updated: 2024-03-25T23:30:23Z
day: '28'
ddc:
- '570'
department:
- _id: SiHi
- _id: MaLo
doi: 10.3389/fncel.2017.00176
ec_funded: 1
external_id:
  isi:
  - '000404486700001'
file:
- access_level: open_access
  checksum: dc1f5a475b918d09a0f9f587400b1626
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:09:40Z
  date_updated: 2020-07-14T12:48:16Z
  file_id: '4764'
  file_name: IST-2017-830-v1+1_2017_Hansen_CellPolarity.pdf
  file_size: 2153858
  relation: main_file
file_date_updated: 2020-07-14T12:48:16Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 25D61E48-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '618444'
  name: Molecular Mechanisms of Cerebral Cortex Development
- _id: 25D7962E-B435-11E9-9278-68D0E5697425
  grant_number: RGP0053/2014
  name: Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal
    Level
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 25985A36-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: T00817-B21
  name: The biochemical basis of PAR polarization
publication: Frontiers in Cellular Neuroscience
publication_identifier:
  issn:
  - '16625102'
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '6445'
pubrep_id: '830'
quality_controlled: '1'
related_material:
  record:
  - id: '9962'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Cell polarity in cerebral cortex development - cellular architecture shaped
  by biochemical networks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 11
year: '2017'
...
---
_id: '961'
abstract:
- lang: eng
  text: Cell-cell  contact  formation  constitutes  the  first  step  in  the  emergence  of  multicellularity  in
    evolution, thereby  allowing  the  differentiation  of  specialized  cell  types.  In  metazoan
    development, cell-cell contact formation is thought to influence cell fate specification,
    and cell   fate   specification   has   been   implicated   in   cell-cell  contact
    formation.   However, remarkably little is yet known about whether and how the
    interaction and feedback between cell-cell contact formation and cell fate specification
    affect development. Here we identify a positive  feedback  loop  between  cell-cell  contact  duration,  morphogen  signaling  and
    mesendoderm  cell  fate  specification  during  zebrafish  gastrulation.  We  show  that  long
    lasting cell-cell contacts enhance the competence of prechordal plate (ppl) progenitor
    cells to  respond  to  Nodal  signaling,  required  for  proper  ppl  cell  fate  specification.  We  further
    show  that  Nodal  signalling  romotes  ppl  cell-cell  contact  duration,  thereby  generating  an
    effective  positive  feedback  loop  between  ppl  cell-cell  contact  duration  and  cell  fate
    specification. Finally, by using a combination of theoretical modeling and experimentation,
    we  show  that  this  feedback  loop  determines  whether  anterior  axial  mesendoderm  cells
    become  ppl  progenitors  or,  instead,  turn  into  endoderm  progenitors.  Our  findings  reveal
    that  the  gene  regulatory  networks  leading  to  cell  fate  diversification  within  the  developing
    embryo  are  controlled  by  the  interdependent  activities  of  cell-cell  signaling  and  contact
    formation.
acknowledgement: "Many people accompanied me during this trip: I would not have reached
  my destination nor \r\nenjoyed the travelling without them. First of all, thanks
  to CP. Thanks for making me part of \r\nyour team, always full of diverse, interesting
  and incredibly competent people and thanks for \r\nall  the  good  science  I  witnessed
  \ and  participated  in.  It  has  been  a \r\nblast,  an  incredibly \r\nexciting
  \ one!  Thanks  to  JLo,  for  teaching  me  how  to  master  my  pipettes  and
  \ showing  me \r\nthat science is a lot of fun. Many, many thanks to Gabby for teaching
  me basically everything \r\nabout  zebrafish  and  being  always  there  to  advice,
  \ sugge\r\nst,  support...and  play  fussball! \r\nThank you to Julien, for the
  critical eye on things, Pedro, for all the invaluable feedback and \r\nthe amazing
  kicker matches, and Keisuke, for showing me the light, and to the three of them
  \r\ntogether  for  all  the  good  laughs  we\r\nhad.  My  start  in  Vienna  would
  \ have  been  a  lot  more \r\ndifficult  without  you  guys.  Also  it  would  not
  \ have  been  possible  without  Elena  and  Inês: \r\nthanks  for  helping  setting
  \ up  this  lab  and  for  the  dinners  in  Gugging.  Thanks  to  Martin,  for
  \r\nhelping  me  understand \r\nthe  physics  behind  biology.  Thanks  to  Philipp,
  \ for  the  interest  and \r\nadvice, and to Michael, for the Viennise take on things.
  Thanks to Julia, for putting up with \r\nbeing our technician and becoming a friend
  in the process. And now to the newest members \r\nof th\r\ne lab. Thanks to Daniel
  for the enthusiasm and the neverending energy and for all your \r\nhelp over the
  years: thank you! To Jana, for showing me that one doesn’t give up, no matter \r\nwhat.
  \ To  Shayan,  for  being  such  a  motivated  student.  To  Matt,  for  helping
  \ out\r\nwith  coding \r\nand for finding punk solutions to data analysis problems.
  Thanks to all the members of the \r\nlab, Verena, Hitoshi, Silvia, Conny, Karla,
  Nicoletta, Zoltan, Peng, Benoit, Roland, Yuuta and \r\nFeyza,  for  the  wonderful
  \ atmosphere  in  the  lab.  Many  than\r\nks  to  Koni  and  Deborah:  doing \r\nexperiments
  would have been much more difficult without your help. Special thanks to Katjia
  \r\nfor  setting  up  an  amazing  imaging  facility  and  for  building  the  best
  \ team,  Robert,  Nasser, \r\nAnna and Doreen: thank you for putting up w\r\nith
  all the late sortings and for helping with all \r\nthe technical problems. Thanks
  to Eva, Verena and Matthias for keeping the fish happy. Big \r\nthanks to Harald
  Janovjak for being a present and helpful committee member over the years \r\nand
  \ to  Patrick  Lemaire  f\r\nor  the  helpful  insight  and  extremely  interesting
  \ discussion  we  had \r\nabout  the  project.  Also,  this  journey  would  not
  \ have  been  the  same  without  all  the  friends \r\nthat I met in Dresden and
  then in Vienna: Daniele, Claire, Kuba, Steffi, Harold, Dejan, Irene, \r\nFab\r\nienne,
  Hande, Tiago, Marianne, Jon, Srdjan, Branca, Uli, Murat, Alex, Conny, Christoph,
  \r\nCaro, Simone, Barbara, Felipe, Dama, Jose, Hubert and many others that filled
  my days with \r\nfun and support. A special thank to my family, always close even
  if they are \r\nkilometers away. \r\nGrazie  ai  miei  fratelli,  Nunzio  e  William,
  \ e  alla  mia  mamma,  per  essermi  sempre  vicini  pur \r\nvivendo a chilometri
  di distanza. And, last but not least, thanks to Moritz, for putting up with \r\nthe
  crazy life of a scientist, the living apart for\r\nso long, never knowing when things
  are going \r\nto happen. Thanks for being a great partner and my number one fan!"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Vanessa
  full_name: Barone, Vanessa
  id: 419EECCC-F248-11E8-B48F-1D18A9856A87
  last_name: Barone
  orcid: 0000-0003-2676-3367
citation:
  ama: 'Barone V. Cell adhesion and cell fate: An effective feedback loop during zebrafish
    gastrulation. 2017. doi:<a href="https://doi.org/10.15479/AT:ISTA:th_825">10.15479/AT:ISTA:th_825</a>'
  apa: 'Barone, V. (2017). <i>Cell adhesion and cell fate: An effective feedback loop
    during zebrafish gastrulation</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT:ISTA:th_825">https://doi.org/10.15479/AT:ISTA:th_825</a>'
  chicago: 'Barone, Vanessa. “Cell Adhesion and Cell Fate: An Effective Feedback Loop
    during Zebrafish Gastrulation.” Institute of Science and Technology Austria, 2017.
    <a href="https://doi.org/10.15479/AT:ISTA:th_825">https://doi.org/10.15479/AT:ISTA:th_825</a>.'
  ieee: 'V. Barone, “Cell adhesion and cell fate: An effective feedback loop during
    zebrafish gastrulation,” Institute of Science and Technology Austria, 2017.'
  ista: 'Barone V. 2017. Cell adhesion and cell fate: An effective feedback loop during
    zebrafish gastrulation. Institute of Science and Technology Austria.'
  mla: 'Barone, Vanessa. <i>Cell Adhesion and Cell Fate: An Effective Feedback Loop
    during Zebrafish Gastrulation</i>. Institute of Science and Technology Austria,
    2017, doi:<a href="https://doi.org/10.15479/AT:ISTA:th_825">10.15479/AT:ISTA:th_825</a>.'
  short: 'V. Barone, Cell Adhesion and Cell Fate: An Effective Feedback Loop during
    Zebrafish Gastrulation, Institute of Science and Technology Austria, 2017.'
date_created: 2018-12-11T11:49:25Z
date_published: 2017-03-01T00:00:00Z
date_updated: 2023-09-27T14:16:45Z
day: '01'
ddc:
- '570'
- '590'
degree_awarded: PhD
department:
- _id: CaHe
doi: 10.15479/AT:ISTA:th_825
file:
- access_level: closed
  checksum: 242f88c87f2cf267bf05049fa26a687b
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  creator: dernst
  date_created: 2019-04-05T08:36:52Z
  date_updated: 2020-07-14T12:48:16Z
  file_id: '6205'
  file_name: 2017_Barone_thesis_final.docx
  file_size: 14497822
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  date_created: 2019-04-05T08:36:52Z
  date_updated: 2020-07-14T12:48:16Z
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  file_name: 2017_Barone_thesis_.pdf
  file_size: 14995941
  relation: main_file
file_date_updated: 2020-07-14T12:48:16Z
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '109'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '6444'
pubrep_id: '825'
related_material:
  record:
  - id: '1100'
    relation: part_of_dissertation
    status: public
  - id: '1537'
    relation: part_of_dissertation
    status: public
  - id: '1912'
    relation: part_of_dissertation
    status: public
  - id: '2926'
    relation: part_of_dissertation
    status: public
  - id: '3246'
    relation: part_of_dissertation
    status: public
  - id: '676'
    relation: part_of_dissertation
    status: public
  - id: '735'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
title: 'Cell adhesion and cell fate: An effective feedback loop during zebrafish gastrulation'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2017'
...
---
_id: '963'
abstract:
- lang: eng
  text: 'Network games are widely used as a model for selfish resource-allocation
    problems. In the classical model, each player selects a path connecting her source
    and target vertex. The cost of traversing an edge depends on the number of players
    that traverse it. Thus, it abstracts the fact that different users may use a resource
    at different times and for different durations, which plays an important role
    in defining the costs of the users in reality. For example, when transmitting
    packets in a communication network, routing traffic in a road network, or processing
    a task in a production system, the traversal of the network involves an inherent
    delay, and so sharing and congestion of resources crucially depends on time. We
    study timed network games , which add a time component to network games. Each
    vertex v in the network is associated with a cost function, mapping the load on
    v to the price that a player pays for staying in v for one time unit with this
    load. In addition, each edge has a guard, describing time intervals in which the
    edge can be traversed, forcing the players to spend time on vertices. Unlike earlier
    work that add a time component to network games, the time in our model is continuous
    and cannot be discretized. In particular, players have uncountably many strategies,
    and a game may have uncountably many pure Nash equilibria. We study properties
    of timed network games with cost-sharing or congestion cost functions: their stability,
    equilibrium inefficiency, and complexity. In particular, we show that the answer
    to the question whether we can restrict attention to boundary strategies, namely
    ones in which edges are traversed only at the boundaries of guards, is mixed. '
alternative_title:
- LIPIcs
article_number: '37'
author:
- first_name: Guy
  full_name: Avni, Guy
  id: 463C8BC2-F248-11E8-B48F-1D18A9856A87
  last_name: Avni
  orcid: 0000-0001-5588-8287
- first_name: Shibashis
  full_name: Guha, Shibashis
  last_name: Guha
- first_name: Orna
  full_name: Kupferman, Orna
  last_name: Kupferman
citation:
  ama: 'Avni G, Guha S, Kupferman O. Timed network games with clocks. In: Vol 83.
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2017. doi:<a href="https://doi.org/10.4230/LIPIcs.MFCS.2017.37">10.4230/LIPIcs.MFCS.2017.37</a>'
  apa: 'Avni, G., Guha, S., &#38; Kupferman, O. (2017). Timed network games with clocks
    (Vol. 83). Presented at the MFCS: Mathematical Foundations of Computer Science
    (SG), Aalborg, Denmark: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a
    href="https://doi.org/10.4230/LIPIcs.MFCS.2017.37">https://doi.org/10.4230/LIPIcs.MFCS.2017.37</a>'
  chicago: Avni, Guy, Shibashis Guha, and Orna Kupferman. “Timed Network Games with
    Clocks,” Vol. 83. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017. <a
    href="https://doi.org/10.4230/LIPIcs.MFCS.2017.37">https://doi.org/10.4230/LIPIcs.MFCS.2017.37</a>.
  ieee: 'G. Avni, S. Guha, and O. Kupferman, “Timed network games with clocks,” presented
    at the MFCS: Mathematical Foundations of Computer Science (SG), Aalborg, Denmark,
    2017, vol. 83.'
  ista: 'Avni G, Guha S, Kupferman O. 2017. Timed network games with clocks. MFCS:
    Mathematical Foundations of Computer Science (SG), LIPIcs, vol. 83, 37.'
  mla: Avni, Guy, et al. <i>Timed Network Games with Clocks</i>. Vol. 83, 37, Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2017, doi:<a href="https://doi.org/10.4230/LIPIcs.MFCS.2017.37">10.4230/LIPIcs.MFCS.2017.37</a>.
  short: G. Avni, S. Guha, O. Kupferman, in:, Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2017.
conference:
  end_date: 2017-08-25
  location: Aalborg, Denmark
  name: 'MFCS: Mathematical Foundations of Computer Science (SG)'
  start_date: 2017-08-21
date_created: 2018-12-11T11:49:26Z
date_published: 2017-06-01T00:00:00Z
date_updated: 2023-02-23T12:35:50Z
day: '01'
ddc:
- '004'
department:
- _id: ToHe
doi: 10.4230/LIPIcs.MFCS.2017.37
file:
- access_level: open_access
  checksum: f55eaf7f3c36ea07801112acfedd17d5
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:10Z
  date_updated: 2020-07-14T12:48:18Z
  file_id: '5059'
  file_name: IST-2017-829-v1+1_mfcs-cr.pdf
  file_size: 369730
  relation: main_file
file_date_updated: 2020-07-14T12:48:18Z
has_accepted_license: '1'
intvolume: '        83'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11402-N23
  name: Moderne Concurrency Paradigms
publication_identifier:
  issn:
  - '18688969'
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '6438'
pubrep_id: '829'
quality_controlled: '1'
related_material:
  record:
  - id: '6005'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: Timed network games with clocks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 83
year: '2017'
...
---
_id: '9660'
abstract:
- lang: eng
  text: In this paper we discuss how the information contained in atomistic simulations
    of homogeneous nucleation should be used when fitting the parameters in macroscopic
    nucleation models. We show how the number of solid and liquid atoms in such simulations
    can be determined unambiguously by using a Gibbs dividing surface and how the
    free energy as a function of the number of solid atoms in the nucleus can thus
    be extracted. We then show that the parameters (the chemical potential, the interfacial
    free energy, and a Tolman correction) of a model based on classical nucleation
    theory can be fitted using the information contained in these free-energy profiles
    but that the parameters in such models are highly correlated. This correlation
    is unfortunate as it ensures that small errors in the computed free energy surface
    can give rise to large errors in the extrapolated properties of the fitted model.
    To resolve this problem we thus propose a method for fitting macroscopic nucleation
    models that uses simulations of planar interfaces and simulations of three-dimensional
    nuclei in tandem. We show that when the chemical potentials and the interface
    energy are pinned to their planar-interface values, more precise estimates for
    the Tolman length are obtained. Extrapolating the free energy profile obtained
    from small simulation boxes to larger nuclei is thus more reliable.
article_number: '104707'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Bingqing
  full_name: Cheng, Bingqing
  id: cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9
  last_name: Cheng
  orcid: 0000-0002-3584-9632
- first_name: Gareth A.
  full_name: Tribello, Gareth A.
  last_name: Tribello
- first_name: Michele
  full_name: Ceriotti, Michele
  last_name: Ceriotti
citation:
  ama: 'Cheng B, Tribello GA, Ceriotti M. The Gibbs free energy of homogeneous nucleation:
    From atomistic nuclei to the planar limit. <i>The Journal of Chemical Physics</i>.
    2017;147(10). doi:<a href="https://doi.org/10.1063/1.4997180">10.1063/1.4997180</a>'
  apa: 'Cheng, B., Tribello, G. A., &#38; Ceriotti, M. (2017). The Gibbs free energy
    of homogeneous nucleation: From atomistic nuclei to the planar limit. <i>The Journal
    of Chemical Physics</i>. AIP Publishing. <a href="https://doi.org/10.1063/1.4997180">https://doi.org/10.1063/1.4997180</a>'
  chicago: 'Cheng, Bingqing, Gareth A. Tribello, and Michele Ceriotti. “The Gibbs
    Free Energy of Homogeneous Nucleation: From Atomistic Nuclei to the Planar Limit.”
    <i>The Journal of Chemical Physics</i>. AIP Publishing, 2017. <a href="https://doi.org/10.1063/1.4997180">https://doi.org/10.1063/1.4997180</a>.'
  ieee: 'B. Cheng, G. A. Tribello, and M. Ceriotti, “The Gibbs free energy of homogeneous
    nucleation: From atomistic nuclei to the planar limit,” <i>The Journal of Chemical
    Physics</i>, vol. 147, no. 10. AIP Publishing, 2017.'
  ista: 'Cheng B, Tribello GA, Ceriotti M. 2017. The Gibbs free energy of homogeneous
    nucleation: From atomistic nuclei to the planar limit. The Journal of Chemical
    Physics. 147(10), 104707.'
  mla: 'Cheng, Bingqing, et al. “The Gibbs Free Energy of Homogeneous Nucleation:
    From Atomistic Nuclei to the Planar Limit.” <i>The Journal of Chemical Physics</i>,
    vol. 147, no. 10, 104707, AIP Publishing, 2017, doi:<a href="https://doi.org/10.1063/1.4997180">10.1063/1.4997180</a>.'
  short: B. Cheng, G.A. Tribello, M. Ceriotti, The Journal of Chemical Physics 147
    (2017).
date_created: 2021-07-15T08:13:29Z
date_published: 2017-09-14T00:00:00Z
date_updated: 2023-02-23T14:04:02Z
day: '14'
doi: 10.1063/1.4997180
extern: '1'
external_id:
  arxiv:
  - '1703.06062'
  pmid:
  - '28915742'
intvolume: '       147'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://pure.qub.ac.uk/en/publications/the-gibbs-free-energy-of-homogeneous-nucleation-from-atomistic-nuclei-to-the-planar-limit(4599cdb4-dcc4-4522-8763-7b2a165ebf12).html
month: '09'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: The Journal of Chemical Physics
publication_identifier:
  eissn:
  - 1089-7690
  issn:
  - 0021-9606
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The Gibbs free energy of homogeneous nucleation: From atomistic nuclei to
  the planar limit'
type: journal_article
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 147
year: '2017'
...
---
_id: '9661'
abstract:
- lang: eng
  text: Macroscopic theories of nucleation such as classical nucleation theory envision
    that clusters of the bulk stable phase form inside the bulk metastable phase.
    Molecular dynamics simulations are often used to elucidate nucleation mechanisms,
    by capturing the microscopic configurations of all the atoms. In this paper, we
    introduce a thermodynamic model that links macroscopic theories and atomic-scale
    simulations and thus provide a simple and elegant framework for testing the limits
    of classical nucleation theory.
article_number: '034106'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Bingqing
  full_name: Cheng, Bingqing
  id: cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9
  last_name: Cheng
  orcid: 0000-0002-3584-9632
- first_name: Michele
  full_name: Ceriotti, Michele
  last_name: Ceriotti
citation:
  ama: Cheng B, Ceriotti M. Bridging the gap between atomistic and macroscopic models
    of homogeneous nucleation. <i>The Journal of Chemical Physics</i>. 2017;146(3).
    doi:<a href="https://doi.org/10.1063/1.4973883">10.1063/1.4973883</a>
  apa: Cheng, B., &#38; Ceriotti, M. (2017). Bridging the gap between atomistic and
    macroscopic models of homogeneous nucleation. <i>The Journal of Chemical Physics</i>.
    AIP Publishing. <a href="https://doi.org/10.1063/1.4973883">https://doi.org/10.1063/1.4973883</a>
  chicago: Cheng, Bingqing, and Michele Ceriotti. “Bridging the Gap between Atomistic
    and Macroscopic Models of Homogeneous Nucleation.” <i>The Journal of Chemical
    Physics</i>. AIP Publishing, 2017. <a href="https://doi.org/10.1063/1.4973883">https://doi.org/10.1063/1.4973883</a>.
  ieee: B. Cheng and M. Ceriotti, “Bridging the gap between atomistic and macroscopic
    models of homogeneous nucleation,” <i>The Journal of Chemical Physics</i>, vol.
    146, no. 3. AIP Publishing, 2017.
  ista: Cheng B, Ceriotti M. 2017. Bridging the gap between atomistic and macroscopic
    models of homogeneous nucleation. The Journal of Chemical Physics. 146(3), 034106.
  mla: Cheng, Bingqing, and Michele Ceriotti. “Bridging the Gap between Atomistic
    and Macroscopic Models of Homogeneous Nucleation.” <i>The Journal of Chemical
    Physics</i>, vol. 146, no. 3, 034106, AIP Publishing, 2017, doi:<a href="https://doi.org/10.1063/1.4973883">10.1063/1.4973883</a>.
  short: B. Cheng, M. Ceriotti, The Journal of Chemical Physics 146 (2017).
date_created: 2021-07-15T08:27:31Z
date_published: 2017-01-21T00:00:00Z
date_updated: 2021-08-09T12:31:57Z
day: '21'
doi: 10.1063/1.4973883
extern: '1'
external_id:
  arxiv:
  - '1610.01322'
  pmid:
  - '28109231'
intvolume: '       146'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1610.01322
month: '01'
oa: 1
oa_version: Preprint
pmid: 1
publication: The Journal of Chemical Physics
publication_identifier:
  eissn:
  - 1089-7690
  issn:
  - 0021-9606
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bridging the gap between atomistic and macroscopic models of homogeneous nucleation
type: journal_article
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 146
year: '2017'
...
---
_id: '9707'
abstract:
- lang: eng
  text: Branching morphogenesis of the epithelial ureteric bud forms the renal collecting
    duct system and is critical for normal nephron number, while low nephron number
    is implicated in hypertension and renal disease. Ureteric bud growth and branching
    requires GDNF signaling from the surrounding mesenchyme to cells at the ureteric
    bud tips, via the Ret receptor tyrosine kinase and coreceptor Gfrα1; Ret signaling
    up-regulates transcription factors Etv4 and Etv5, which are also critical for
    branching. Despite extensive knowledge of the genetic control of these events,
    it is not understood, at the cellular level, how renal branching morphogenesis
    is achieved or how Ret signaling influences epithelial cell behaviors to promote
    this process. Analysis of chimeric embryos previously suggested a role for Ret
    signaling in promoting cell rearrangements in the nephric duct, but this method
    was unsuited to study individual cell behaviors during ureteric bud branching.
    Here, we use Mosaic Analysis with Double Markers (MADM), combined with organ culture
    and time-lapse imaging, to trace the movements and divisions of individual ureteric
    bud tip cells. We first examine wild-type clones and then Ret or Etv4 mutant/wild-type
    clones in which the mutant and wild-type sister cells are differentially and heritably
    marked by green and red fluorescent proteins. We find that, in normal kidneys,
    most individual tip cells behave as self-renewing progenitors, some of whose progeny
    remain at the tips while others populate the growing UB trunks. In Ret or Etv4
    MADM clones, the wild-type cells generated at a UB tip are much more likely to
    remain at, or move to, the new tips during branching and elongation, while their
    Ret−/− or Etv4−/− sister cells tend to lag behind and contribute only to the trunks.
    By tracking successive mitoses in a cell lineage, we find that Ret signaling has
    little effect on proliferation, in contrast to its effects on cell movement. Our
    results show that Ret/Etv4 signaling promotes directed cell movements in the ureteric
    bud tips, and suggest a model in which these cell movements mediate branching
    morphogenesis.
article_processing_charge: No
author:
- first_name: Paul
  full_name: Riccio, Paul
  last_name: Riccio
- first_name: Christina
  full_name: Cebrián, Christina
  last_name: Cebrián
- first_name: Hui
  full_name: Zong, Hui
  last_name: Zong
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Frank
  full_name: Costantini, Frank
  last_name: Costantini
citation:
  ama: 'Riccio P, Cebrián C, Zong H, Hippenmeyer S, Costantini F. Data from: Ret and
    Etv4 promote directed movements of progenitor cells during renal branching morphogenesis.
    2017. doi:<a href="https://doi.org/10.5061/dryad.pk16b">10.5061/dryad.pk16b</a>'
  apa: 'Riccio, P., Cebrián, C., Zong, H., Hippenmeyer, S., &#38; Costantini, F. (2017).
    Data from: Ret and Etv4 promote directed movements of progenitor cells during
    renal branching morphogenesis. Dryad. <a href="https://doi.org/10.5061/dryad.pk16b">https://doi.org/10.5061/dryad.pk16b</a>'
  chicago: 'Riccio, Paul, Christina Cebrián, Hui Zong, Simon Hippenmeyer, and Frank
    Costantini. “Data from: Ret and Etv4 Promote Directed Movements of Progenitor
    Cells during Renal Branching Morphogenesis.” Dryad, 2017. <a href="https://doi.org/10.5061/dryad.pk16b">https://doi.org/10.5061/dryad.pk16b</a>.'
  ieee: 'P. Riccio, C. Cebrián, H. Zong, S. Hippenmeyer, and F. Costantini, “Data
    from: Ret and Etv4 promote directed movements of progenitor cells during renal
    branching morphogenesis.” Dryad, 2017.'
  ista: 'Riccio P, Cebrián C, Zong H, Hippenmeyer S, Costantini F. 2017. Data from:
    Ret and Etv4 promote directed movements of progenitor cells during renal branching
    morphogenesis, Dryad, <a href="https://doi.org/10.5061/dryad.pk16b">10.5061/dryad.pk16b</a>.'
  mla: 'Riccio, Paul, et al. <i>Data from: Ret and Etv4 Promote Directed Movements
    of Progenitor Cells during Renal Branching Morphogenesis</i>. Dryad, 2017, doi:<a
    href="https://doi.org/10.5061/dryad.pk16b">10.5061/dryad.pk16b</a>.'
  short: P. Riccio, C. Cebrián, H. Zong, S. Hippenmeyer, F. Costantini, (2017).
date_created: 2021-07-23T09:39:34Z
date_published: 2017-01-14T00:00:00Z
date_updated: 2022-08-25T13:34:55Z
day: '14'
department:
- _id: SiHi
doi: 10.5061/dryad.pk16b
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.pk16b
month: '01'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '9702'
    relation: used_in_publication
    status: deleted
status: public
title: 'Data from: Ret and Etv4 promote directed movements of progenitor cells during
  renal branching morphogenesis'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2017'
...
---
_id: '9709'
abstract:
- lang: eng
  text: Across the nervous system, certain population spiking patterns are observed
    far more frequently than others. A hypothesis about this structure is that these
    collective activity patterns function as population codewords–collective modes–carrying
    information distinct from that of any single cell. We investigate this phenomenon
    in recordings of ∼150 retinal ganglion cells, the retina’s output. We develop
    a novel statistical model that decomposes the population response into modes;
    it predicts the distribution of spiking activity in the ganglion cell population
    with high accuracy. We found that the modes represent localized features of the
    visual stimulus that are distinct from the features represented by single neurons.
    Modes form clusters of activity states that are readily discriminated from one
    another. When we repeated the same visual stimulus, we found that the same mode
    was robustly elicited. These results suggest that retinal ganglion cells’ collective
    signaling is endowed with a form of error-correcting code–a principle that may
    hold in brain areas beyond retina.
article_processing_charge: No
author:
- first_name: Jason
  full_name: Prentice, Jason
  last_name: Prentice
- first_name: Olivier
  full_name: Marre, Olivier
  last_name: Marre
- first_name: Mark
  full_name: Ioffe, Mark
  last_name: Ioffe
- first_name: Adrianna
  full_name: Loback, Adrianna
  last_name: Loback
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
- first_name: Michael
  full_name: Berry, Michael
  last_name: Berry
citation:
  ama: 'Prentice J, Marre O, Ioffe M, Loback A, Tkačik G, Berry M. Data from: Error-robust
    modes of the retinal population code. 2017. doi:<a href="https://doi.org/10.5061/dryad.1f1rc">10.5061/dryad.1f1rc</a>'
  apa: 'Prentice, J., Marre, O., Ioffe, M., Loback, A., Tkačik, G., &#38; Berry, M.
    (2017). Data from: Error-robust modes of the retinal population code. Dryad. <a
    href="https://doi.org/10.5061/dryad.1f1rc">https://doi.org/10.5061/dryad.1f1rc</a>'
  chicago: 'Prentice, Jason, Olivier Marre, Mark Ioffe, Adrianna Loback, Gašper Tkačik,
    and Michael Berry. “Data from: Error-Robust Modes of the Retinal Population Code.”
    Dryad, 2017. <a href="https://doi.org/10.5061/dryad.1f1rc">https://doi.org/10.5061/dryad.1f1rc</a>.'
  ieee: 'J. Prentice, O. Marre, M. Ioffe, A. Loback, G. Tkačik, and M. Berry, “Data
    from: Error-robust modes of the retinal population code.” Dryad, 2017.'
  ista: 'Prentice J, Marre O, Ioffe M, Loback A, Tkačik G, Berry M. 2017. Data from:
    Error-robust modes of the retinal population code, Dryad, <a href="https://doi.org/10.5061/dryad.1f1rc">10.5061/dryad.1f1rc</a>.'
  mla: 'Prentice, Jason, et al. <i>Data from: Error-Robust Modes of the Retinal Population
    Code</i>. Dryad, 2017, doi:<a href="https://doi.org/10.5061/dryad.1f1rc">10.5061/dryad.1f1rc</a>.'
  short: J. Prentice, O. Marre, M. Ioffe, A. Loback, G. Tkačik, M. Berry, (2017).
date_created: 2021-07-23T11:34:34Z
date_published: 2017-10-18T00:00:00Z
date_updated: 2023-02-21T16:34:41Z
day: '18'
department:
- _id: GaTk
doi: 10.5061/dryad.1f1rc
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.1f1rc
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '1197'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Error-robust modes of the retinal population code'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2017'
...
---
_id: '9842'
abstract:
- lang: eng
  text: Mathematica notebooks used to generate figures.
article_processing_charge: No
author:
- first_name: Alison
  full_name: Etheridge, Alison
  last_name: Etheridge
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: 'Etheridge A, Barton NH. Data for: Establishment in a new habitat by polygenic
    adaptation. 2017. doi:<a href="https://doi.org/10.17632/nw68fxzjpm.1">10.17632/nw68fxzjpm.1</a>'
  apa: 'Etheridge, A., &#38; Barton, N. H. (2017). Data for: Establishment in a new
    habitat by polygenic adaptation. Mendeley Data. <a href="https://doi.org/10.17632/nw68fxzjpm.1">https://doi.org/10.17632/nw68fxzjpm.1</a>'
  chicago: 'Etheridge, Alison, and Nicholas H Barton. “Data for: Establishment in
    a New Habitat by Polygenic Adaptation.” Mendeley Data, 2017. <a href="https://doi.org/10.17632/nw68fxzjpm.1">https://doi.org/10.17632/nw68fxzjpm.1</a>.'
  ieee: 'A. Etheridge and N. H. Barton, “Data for: Establishment in a new habitat
    by polygenic adaptation.” Mendeley Data, 2017.'
  ista: 'Etheridge A, Barton NH. 2017. Data for: Establishment in a new habitat by
    polygenic adaptation, Mendeley Data, <a href="https://doi.org/10.17632/nw68fxzjpm.1">10.17632/nw68fxzjpm.1</a>.'
  mla: 'Etheridge, Alison, and Nicholas H. Barton. <i>Data for: Establishment in a
    New Habitat by Polygenic Adaptation</i>. Mendeley Data, 2017, doi:<a href="https://doi.org/10.17632/nw68fxzjpm.1">10.17632/nw68fxzjpm.1</a>.'
  short: A. Etheridge, N.H. Barton, (2017).
date_created: 2021-08-09T13:18:55Z
date_published: 2017-12-29T00:00:00Z
date_updated: 2025-05-28T11:56:59Z
day: '29'
department:
- _id: NiBa
doi: 10.17632/nw68fxzjpm.1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.17632/nw68fxzjpm.1
month: '12'
oa: 1
oa_version: Published Version
publisher: Mendeley Data
related_material:
  record:
  - id: '564'
    relation: used_in_publication
    status: public
status: public
title: 'Data for: Establishment in a new habitat by polygenic adaptation'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2017'
...
---
_id: '9847'
abstract:
- lang: eng
  text: information on culture conditions, phage mutagenesis, verification and lysate
    preparation; Raw data
article_processing_charge: No
author:
- first_name: Maros
  full_name: Pleska, Maros
  id: 4569785E-F248-11E8-B48F-1D18A9856A87
  last_name: Pleska
  orcid: 0000-0001-7460-7479
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
citation:
  ama: Pleska M, Guet CC. Supplementary materials and methods; Full data set from
    effects of mutations in phage restriction sites during escape from restriction–modification.
    2017. doi:<a href="https://doi.org/10.6084/m9.figshare.5633917.v1">10.6084/m9.figshare.5633917.v1</a>
  apa: Pleska, M., &#38; Guet, C. C. (2017). Supplementary materials and methods;
    Full data set from effects of mutations in phage restriction sites during escape
    from restriction–modification. The Royal Society. <a href="https://doi.org/10.6084/m9.figshare.5633917.v1">https://doi.org/10.6084/m9.figshare.5633917.v1</a>
  chicago: Pleska, Maros, and Calin C Guet. “Supplementary Materials and Methods;
    Full Data Set from Effects of Mutations in Phage Restriction Sites during Escape
    from Restriction–Modification.” The Royal Society, 2017. <a href="https://doi.org/10.6084/m9.figshare.5633917.v1">https://doi.org/10.6084/m9.figshare.5633917.v1</a>.
  ieee: M. Pleska and C. C. Guet, “Supplementary materials and methods; Full data
    set from effects of mutations in phage restriction sites during escape from restriction–modification.”
    The Royal Society, 2017.
  ista: Pleska M, Guet CC. 2017. Supplementary materials and methods; Full data set
    from effects of mutations in phage restriction sites during escape from restriction–modification,
    The Royal Society, <a href="https://doi.org/10.6084/m9.figshare.5633917.v1">10.6084/m9.figshare.5633917.v1</a>.
  mla: Pleska, Maros, and Calin C. Guet. <i>Supplementary Materials and Methods; Full
    Data Set from Effects of Mutations in Phage Restriction Sites during Escape from
    Restriction–Modification</i>. The Royal Society, 2017, doi:<a href="https://doi.org/10.6084/m9.figshare.5633917.v1">10.6084/m9.figshare.5633917.v1</a>.
  short: M. Pleska, C.C. Guet, (2017).
date_created: 2021-08-09T13:54:38Z
date_published: 2017-11-27T00:00:00Z
date_updated: 2023-02-23T12:29:44Z
day: '27'
department:
- _id: CaGu
doi: 10.6084/m9.figshare.5633917.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.6084/m9.figshare.5633917.v1
month: '11'
oa: 1
oa_version: Published Version
publisher: The Royal Society
related_material:
  record:
  - id: '561'
    relation: used_in_publication
    status: public
status: public
title: Supplementary materials and methods; Full data set from effects of mutations
  in phage restriction sites during escape from restriction–modification
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2017'
...
---
_id: '9853'
abstract:
- lang: eng
  text: Egg laying rates and infection loads of C. obscurior queens
article_processing_charge: No
author:
- first_name: Julia
  full_name: Giehr, Julia
  last_name: Giehr
- first_name: Anna V
  full_name: Grasse, Anna V
  id: 406F989C-F248-11E8-B48F-1D18A9856A87
  last_name: Grasse
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
- first_name: Jürgen
  full_name: Heinze, Jürgen
  last_name: Heinze
- first_name: Alexandra
  full_name: Schrempf, Alexandra
  last_name: Schrempf
citation:
  ama: Giehr J, Grasse AV, Cremer S, Heinze J, Schrempf A. Raw data from ant queens
    increase their reproductive efforts after pathogen infection. 2017. doi:<a href="https://doi.org/10.6084/m9.figshare.5117788.v1">10.6084/m9.figshare.5117788.v1</a>
  apa: Giehr, J., Grasse, A. V., Cremer, S., Heinze, J., &#38; Schrempf, A. (2017).
    Raw data from ant queens increase their reproductive efforts after pathogen infection.
    The Royal Society. <a href="https://doi.org/10.6084/m9.figshare.5117788.v1">https://doi.org/10.6084/m9.figshare.5117788.v1</a>
  chicago: Giehr, Julia, Anna V Grasse, Sylvia Cremer, Jürgen Heinze, and Alexandra
    Schrempf. “Raw Data from Ant Queens Increase Their Reproductive Efforts after
    Pathogen Infection.” The Royal Society, 2017. <a href="https://doi.org/10.6084/m9.figshare.5117788.v1">https://doi.org/10.6084/m9.figshare.5117788.v1</a>.
  ieee: J. Giehr, A. V. Grasse, S. Cremer, J. Heinze, and A. Schrempf, “Raw data from
    ant queens increase their reproductive efforts after pathogen infection.” The
    Royal Society, 2017.
  ista: Giehr J, Grasse AV, Cremer S, Heinze J, Schrempf A. 2017. Raw data from ant
    queens increase their reproductive efforts after pathogen infection, The Royal
    Society, <a href="https://doi.org/10.6084/m9.figshare.5117788.v1">10.6084/m9.figshare.5117788.v1</a>.
  mla: Giehr, Julia, et al. <i>Raw Data from Ant Queens Increase Their Reproductive
    Efforts after Pathogen Infection</i>. The Royal Society, 2017, doi:<a href="https://doi.org/10.6084/m9.figshare.5117788.v1">10.6084/m9.figshare.5117788.v1</a>.
  short: J. Giehr, A.V. Grasse, S. Cremer, J. Heinze, A. Schrempf, (2017).
date_created: 2021-08-10T06:57:57Z
date_published: 2017-06-19T00:00:00Z
date_updated: 2023-09-26T15:45:47Z
day: '19'
department:
- _id: SyCr
doi: 10.6084/m9.figshare.5117788.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.6084/m9.figshare.5117788.v1
month: '06'
oa: 1
oa_version: Published Version
publisher: The Royal Society
related_material:
  record:
  - id: '914'
    relation: used_in_publication
    status: public
status: public
title: Raw data from ant queens increase their reproductive efforts after pathogen
  infection
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2017'
...
---
_id: '9859'
abstract:
- lang: eng
  text: 'Lists of all differentially expressed genes in the different priming-challenge
    treatments (compared to the fully naïve control; xlsx file). Relevant columns
    include the following: sample_1 and sample_2 – treatment groups being compared;
    Normalised FPKM sample_1 and sample_2 – FPKM of samples being compared; log2(fold_change)
    – log2(FPKM sample 2/FPKM sample 1), i.e. negative means sample 1 upregulated
    compared with sample 2, positive means sample 2 upregulated compared with sample
    1; cuffdiff test_statistic – test statistic of differential expression test; p_value
    – p-value of differential expression test; q_value (FDR correction) – adjusted
    P-value of differential expression test. (XLSX 598 kb)'
article_processing_charge: No
author:
- first_name: Jenny
  full_name: Greenwood, Jenny
  last_name: Greenwood
- first_name: Barbara
  full_name: Milutinovic, Barbara
  id: 2CDC32B8-F248-11E8-B48F-1D18A9856A87
  last_name: Milutinovic
  orcid: 0000-0002-8214-4758
- first_name: Robert
  full_name: Peuß, Robert
  last_name: Peuß
- first_name: Sarah
  full_name: Behrens, Sarah
  last_name: Behrens
- first_name: Daniela
  full_name: Essar, Daniela
  last_name: Essar
- first_name: Philip
  full_name: Rosenstiel, Philip
  last_name: Rosenstiel
- first_name: Hinrich
  full_name: Schulenburg, Hinrich
  last_name: Schulenburg
- first_name: Joachim
  full_name: Kurtz, Joachim
  last_name: Kurtz
citation:
  ama: 'Greenwood J, Milutinovic B, Peuß R, et al. Additional file 1: Table S1. of
    Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression
    of Tribolium castaneum larvae. 2017. doi:<a href="https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1">10.6084/m9.figshare.c.3756974_d1.v1</a>'
  apa: 'Greenwood, J., Milutinovic, B., Peuß, R., Behrens, S., Essar, D., Rosenstiel,
    P., … Kurtz, J. (2017). Additional file 1: Table S1. of Oral immune priming with
    Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum
    larvae. Springer Nature. <a href="https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1">https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1</a>'
  chicago: 'Greenwood, Jenny, Barbara Milutinovic, Robert Peuß, Sarah Behrens, Daniela
    Essar, Philip Rosenstiel, Hinrich Schulenburg, and Joachim Kurtz. “Additional
    File 1: Table S1. of Oral Immune Priming with Bacillus Thuringiensis Induces a
    Shift in the Gene Expression of Tribolium Castaneum Larvae.” Springer Nature,
    2017. <a href="https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1">https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1</a>.'
  ieee: 'J. Greenwood <i>et al.</i>, “Additional file 1: Table S1. of Oral immune
    priming with Bacillus thuringiensis induces a shift in the gene expression of
    Tribolium castaneum larvae.” Springer Nature, 2017.'
  ista: 'Greenwood J, Milutinovic B, Peuß R, Behrens S, Essar D, Rosenstiel P, Schulenburg
    H, Kurtz J. 2017. Additional file 1: Table S1. of Oral immune priming with Bacillus
    thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae,
    Springer Nature, <a href="https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1">10.6084/m9.figshare.c.3756974_d1.v1</a>.'
  mla: 'Greenwood, Jenny, et al. <i>Additional File 1: Table S1. of Oral Immune Priming
    with Bacillus Thuringiensis Induces a Shift in the Gene Expression of Tribolium
    Castaneum Larvae</i>. Springer Nature, 2017, doi:<a href="https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1">10.6084/m9.figshare.c.3756974_d1.v1</a>.'
  short: J. Greenwood, B. Milutinovic, R. Peuß, S. Behrens, D. Essar, P. Rosenstiel,
    H. Schulenburg, J. Kurtz, (2017).
date_created: 2021-08-10T07:59:02Z
date_published: 2017-04-26T00:00:00Z
date_updated: 2023-09-22T09:47:44Z
day: '26'
department:
- _id: SyCr
doi: 10.6084/m9.figshare.c.3756974_d1.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1
month: '04'
oa: 1
oa_version: Published Version
publisher: Springer Nature
related_material:
  record:
  - id: '1006'
    relation: used_in_publication
    status: public
status: public
title: 'Additional file 1: Table S1. of Oral immune priming with Bacillus thuringiensis
  induces a shift in the gene expression of Tribolium castaneum larvae'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2017'
...
