---
_id: '9891'
abstract:
- lang: eng
  text: 'Extending on ideas of Lewin, Lieb, and Seiringer [Phys. Rev. B 100, 035127
    (2019)], we present a modified “floating crystal” trial state for jellium (also
    known as the classical homogeneous electron gas) with density equal to a characteristic
    function. This allows us to show that three definitions of the jellium energy
    coincide in dimensions d ≥ 2, thus extending the result of Cotar and Petrache
    [“Equality of the Jellium and uniform electron gas next-order asymptotic terms
    for Coulomb and Riesz potentials,” arXiv: 1707.07664 (2019)] and Lewin, Lieb,
    and Seiringer [Phys. Rev. B 100, 035127 (2019)] that the three definitions coincide
    in dimension d ≥ 3. We show that the jellium energy is also equivalent to a “renormalized
    energy” studied in a series of papers by Serfaty and others, and thus, by the
    work of Bétermin and Sandier [Constr. Approximation 47, 39–74 (2018)], we relate
    the jellium energy to the order n term in the logarithmic energy of n points on
    the unit 2-sphere. We improve upon known lower bounds for this renormalized energy.
    Additionally, we derive formulas for the jellium energy of periodic configurations.'
acknowledgement: The author would like to thank Robert Seiringer for guidance and
  many helpful comments on this project. The author would also like to thank Mathieu
  Lewin for his comments on the manuscript and Lorenzo Portinale for providing his
  lecture notes for the course “Mathematics of quantum many-body systems” in spring
  2020, taught by Robert Seiringer. The Proof of Theorem III.1 is inspired by these
  lecture notes.
article_number: '083305'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Asbjørn Bækgaard
  full_name: Lauritsen, Asbjørn Bækgaard
  id: e1a2682f-dc8d-11ea-abe3-81da9ac728f1
  last_name: Lauritsen
  orcid: 0000-0003-4476-2288
citation:
  ama: Lauritsen AB. Floating Wigner crystal and periodic jellium configurations.
    <i>Journal of Mathematical Physics</i>. 2021;62(8). doi:<a href="https://doi.org/10.1063/5.0053494">10.1063/5.0053494</a>
  apa: Lauritsen, A. B. (2021). Floating Wigner crystal and periodic jellium configurations.
    <i>Journal of Mathematical Physics</i>. AIP Publishing. <a href="https://doi.org/10.1063/5.0053494">https://doi.org/10.1063/5.0053494</a>
  chicago: Lauritsen, Asbjørn Bækgaard. “Floating Wigner Crystal and Periodic Jellium
    Configurations.” <i>Journal of Mathematical Physics</i>. AIP Publishing, 2021.
    <a href="https://doi.org/10.1063/5.0053494">https://doi.org/10.1063/5.0053494</a>.
  ieee: A. B. Lauritsen, “Floating Wigner crystal and periodic jellium configurations,”
    <i>Journal of Mathematical Physics</i>, vol. 62, no. 8. AIP Publishing, 2021.
  ista: Lauritsen AB. 2021. Floating Wigner crystal and periodic jellium configurations.
    Journal of Mathematical Physics. 62(8), 083305.
  mla: Lauritsen, Asbjørn Bækgaard. “Floating Wigner Crystal and Periodic Jellium
    Configurations.” <i>Journal of Mathematical Physics</i>, vol. 62, no. 8, 083305,
    AIP Publishing, 2021, doi:<a href="https://doi.org/10.1063/5.0053494">10.1063/5.0053494</a>.
  short: A.B. Lauritsen, Journal of Mathematical Physics 62 (2021).
date_created: 2021-08-12T07:08:36Z
date_published: 2021-08-01T00:00:00Z
date_updated: 2023-08-11T10:29:48Z
day: '01'
ddc:
- '530'
department:
- _id: GradSch
- _id: RoSe
doi: 10.1063/5.0053494
external_id:
  arxiv:
  - '2103.07975'
  isi:
  - '000683960800003'
file:
- access_level: open_access
  checksum: d035be2b894c4d50d90ac5ce252e27cd
  content_type: application/pdf
  creator: cziletti
  date_created: 2021-10-27T12:57:06Z
  date_updated: 2021-10-27T12:57:06Z
  file_id: '10188'
  file_name: 2021_JMathPhy_Lauritsen.pdf
  file_size: 4352640
  relation: main_file
  success: 1
file_date_updated: 2021-10-27T12:57:06Z
has_accepted_license: '1'
intvolume: '        62'
isi: 1
issue: '8'
keyword:
- Mathematical Physics
- Statistical and Nonlinear Physics
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: Journal of Mathematical Physics
publication_identifier:
  eissn:
  - 1089-7658
  issn:
  - 0022-2488
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Floating Wigner crystal and periodic jellium configurations
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 62
year: '2021'
...
---
_id: '9903'
abstract:
- lang: eng
  text: Eigenstate thermalization in quantum many-body systems implies that eigenstates
    at high energy are similar to random vectors. Identifying systems where at least
    some eigenstates are nonthermal is an outstanding question. In this Letter we
    show that interacting quantum models that have a nullspace—a degenerate subspace
    of eigenstates at zero energy (zero modes), which corresponds to infinite temperature,
    provide a route to nonthermal eigenstates. We analytically show the existence
    of a zero mode which can be represented as a matrix product state for a certain
    class of local Hamiltonians. In the more general case we use a subspace disentangling
    algorithm to generate an orthogonal basis of zero modes characterized by increasing
    entanglement entropy. We show evidence for an area-law entanglement scaling of
    the least-entangled zero mode in the broad parameter regime, leading to a conjecture
    that all local Hamiltonians with the nullspace feature zero modes with area-law
    entanglement scaling and, as such, break the strong thermalization hypothesis.
    Finally, we find zero modes in constrained models and propose a setup for observing
    their experimental signatures.
acknowledgement: "We acknowledge useful discussions with V. Gritsev and A. Garkun
  and suggestions on implementation of the\r\nPPXPP model by D. Bluvstein. A. M. and
  M. S. were supported by the European Research Council (ERC) under\r\nthe European
  Union’s Horizon 2020 research and innovation program (Grant Agreement No. 850899)"
article_number: '060602'
article_processing_charge: Yes (in subscription journal)
article_type: letter_note
arxiv: 1
author:
- first_name: Volker
  full_name: Karle, Volker
  id: D7C012AE-D7ED-11E9-95E8-1EC5E5697425
  last_name: Karle
  orcid: 0000-0002-6963-0129
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
- first_name: Alexios
  full_name: Michailidis, Alexios
  id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
  last_name: Michailidis
  orcid: 0000-0002-8443-1064
citation:
  ama: Karle V, Serbyn M, Michailidis A. Area-law entangled eigenstates from nullspaces
    of local Hamiltonians. <i>Physical Review Letters</i>. 2021;127(6). doi:<a href="https://doi.org/10.1103/physrevlett.127.060602">10.1103/physrevlett.127.060602</a>
  apa: Karle, V., Serbyn, M., &#38; Michailidis, A. (2021). Area-law entangled eigenstates
    from nullspaces of local Hamiltonians. <i>Physical Review Letters</i>. American
    Physical Society. <a href="https://doi.org/10.1103/physrevlett.127.060602">https://doi.org/10.1103/physrevlett.127.060602</a>
  chicago: Karle, Volker, Maksym Serbyn, and Alexios Michailidis. “Area-Law Entangled
    Eigenstates from Nullspaces of Local Hamiltonians.” <i>Physical Review Letters</i>.
    American Physical Society, 2021. <a href="https://doi.org/10.1103/physrevlett.127.060602">https://doi.org/10.1103/physrevlett.127.060602</a>.
  ieee: V. Karle, M. Serbyn, and A. Michailidis, “Area-law entangled eigenstates from
    nullspaces of local Hamiltonians,” <i>Physical Review Letters</i>, vol. 127, no.
    6. American Physical Society, 2021.
  ista: Karle V, Serbyn M, Michailidis A. 2021. Area-law entangled eigenstates from
    nullspaces of local Hamiltonians. Physical Review Letters. 127(6), 060602.
  mla: Karle, Volker, et al. “Area-Law Entangled Eigenstates from Nullspaces of Local
    Hamiltonians.” <i>Physical Review Letters</i>, vol. 127, no. 6, 060602, American
    Physical Society, 2021, doi:<a href="https://doi.org/10.1103/physrevlett.127.060602">10.1103/physrevlett.127.060602</a>.
  short: V. Karle, M. Serbyn, A. Michailidis, Physical Review Letters 127 (2021).
date_created: 2021-08-13T09:27:39Z
date_published: 2021-08-06T00:00:00Z
date_updated: 2023-08-11T10:43:27Z
day: '06'
ddc:
- '539'
department:
- _id: MaSe
- _id: GradSch
- _id: MiLe
doi: 10.1103/physrevlett.127.060602
ec_funded: 1
external_id:
  arxiv:
  - '2102.13633'
  isi:
  - '000684276000002'
file:
- access_level: open_access
  checksum: 51218f302dcef99d90d1209809fcc874
  content_type: application/pdf
  creator: mserbyn
  date_created: 2021-08-13T09:28:08Z
  date_updated: 2021-08-13T09:28:08Z
  file_id: '9904'
  file_name: PhysRevLett.127.060602_SOM.pdf
  file_size: 5064231
  relation: main_file
  success: 1
file_date_updated: 2021-08-13T09:28:08Z
has_accepted_license: '1'
intvolume: '       127'
isi: 1
issue: '6'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Area-law entangled eigenstates from nullspaces of local Hamiltonians
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 127
year: '2021'
...
---
_id: '9905'
abstract:
- lang: eng
  text: Vaccines are thought to be the best available solution for controlling the
    ongoing SARS-CoV-2 pandemic. However, the emergence of vaccine-resistant strains
    may come too rapidly for current vaccine developments to alleviate the health,
    economic and social consequences of the pandemic. To quantify and characterize
    the risk of such a scenario, we created a SIR-derived model with initial stochastic
    dynamics of the vaccine-resistant strain to study the probability of its emergence
    and establishment. Using parameters realistically resembling SARS-CoV-2 transmission,
    we model a wave-like pattern of the pandemic and consider the impact of the rate
    of vaccination and the strength of non-pharmaceutical intervention measures on
    the probability of emergence of a resistant strain. As expected, we found that
    a fast rate of vaccination decreases the probability of emergence of a resistant
    strain. Counterintuitively, when a relaxation of non-pharmaceutical interventions
    happened at a time when most individuals of the population have already been vaccinated
    the probability of emergence of a resistant strain was greatly increased. Consequently,
    we show that a period of transmission reduction close to the end of the vaccination
    campaign can substantially reduce the probability of resistant strain establishment.
    Our results suggest that policymakers and individuals should consider maintaining
    non-pharmaceutical interventions and transmission-reducing behaviours throughout
    the entire vaccination period.
acknowledgement: We thank Alexey Kondrashov, Nick Machnik, Raimundo Julian Saona Urmeneta,
  Gasper Tkacik and Nick Barton for fruitful discussions. We also thank participants
  of EvoLunch seminar at IST Austria and the internal seminar at the Banco de España
  for useful comments. The opinions expressed in this document are exclusively of
  the authors and, therefore, do not necessarily coincide with those of the Banco
  de España or the Eurosystem. ETD is supported by the Swiss National Science and
  Louis Jeantet Foundation. The work of FAK was in part supported by the ERC Consolidator
  Grant (771209-CharFL).
article_number: '15729'
article_processing_charge: Yes
article_type: original
author:
- first_name: Simon
  full_name: Rella, Simon
  id: B4765ACA-AA38-11E9-AC9A-0930E6697425
  last_name: Rella
- first_name: Yuliya A.
  full_name: Kulikova, Yuliya A.
  last_name: Kulikova
- first_name: Emmanouil T.
  full_name: Dermitzakis, Emmanouil T.
  last_name: Dermitzakis
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
citation:
  ama: Rella S, Kulikova YA, Dermitzakis ET, Kondrashov F. Rates of SARS-CoV-2 transmission
    and vaccination impact the fate of vaccine-resistant strains. <i>Scientific Reports</i>.
    2021;11(1). doi:<a href="https://doi.org/10.1038/s41598-021-95025-3">10.1038/s41598-021-95025-3</a>
  apa: Rella, S., Kulikova, Y. A., Dermitzakis, E. T., &#38; Kondrashov, F. (2021).
    Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant
    strains. <i>Scientific Reports</i>. Springer Nature. <a href="https://doi.org/10.1038/s41598-021-95025-3">https://doi.org/10.1038/s41598-021-95025-3</a>
  chicago: Rella, Simon, Yuliya A. Kulikova, Emmanouil T. Dermitzakis, and Fyodor
    Kondrashov. “Rates of SARS-CoV-2 Transmission and Vaccination Impact the Fate
    of Vaccine-Resistant Strains.” <i>Scientific Reports</i>. Springer Nature, 2021.
    <a href="https://doi.org/10.1038/s41598-021-95025-3">https://doi.org/10.1038/s41598-021-95025-3</a>.
  ieee: S. Rella, Y. A. Kulikova, E. T. Dermitzakis, and F. Kondrashov, “Rates of
    SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains,”
    <i>Scientific Reports</i>, vol. 11, no. 1. Springer Nature, 2021.
  ista: Rella S, Kulikova YA, Dermitzakis ET, Kondrashov F. 2021. Rates of SARS-CoV-2
    transmission and vaccination impact the fate of vaccine-resistant strains. Scientific
    Reports. 11(1), 15729.
  mla: Rella, Simon, et al. “Rates of SARS-CoV-2 Transmission and Vaccination Impact
    the Fate of Vaccine-Resistant Strains.” <i>Scientific Reports</i>, vol. 11, no.
    1, 15729, Springer Nature, 2021, doi:<a href="https://doi.org/10.1038/s41598-021-95025-3">10.1038/s41598-021-95025-3</a>.
  short: S. Rella, Y.A. Kulikova, E.T. Dermitzakis, F. Kondrashov, Scientific Reports
    11 (2021).
date_created: 2021-08-15T22:01:26Z
date_published: 2021-07-30T00:00:00Z
date_updated: 2023-08-11T10:42:58Z
day: '30'
ddc:
- '570'
- '610'
department:
- _id: FyKo
doi: 10.1038/s41598-021-95025-3
ec_funded: 1
external_id:
  isi:
  - '000683329100001'
  pmid:
  - '34330988'
file:
- access_level: open_access
  checksum: ac86892ed17e6724c7251844da5cef5c
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T11:36:49Z
  date_updated: 2021-08-16T11:36:49Z
  file_id: '9927'
  file_name: 2021_ScientificReports_Rella.pdf
  file_size: 3432001
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T11:36:49Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
issue: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26580278-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '771209'
  name: Characterizing the fitness landscape on population and global scales
publication: Scientific Reports
publication_identifier:
  eissn:
  - '20452322'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Website
    relation: press_release
    url: https://ist.ac.at/en/news/counterintuitive-dynamics-threaten-the-end-of-the-pandemic/
scopus_import: '1'
status: public
title: Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant
  strains
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2021'
...
---
_id: '9906'
abstract:
- lang: eng
  text: Endometriosis is a common gynecological disorder characterized by ectopic
    growth of endometrium outside the uterus and is associated with chronic pain and
    infertility. We investigated the role of the long intergenic noncoding RNA 01133
    (LINC01133) in endometriosis, an lncRNA that has been implicated in several types
    of cancer. We found that LINC01133 is upregulated in ectopic endometriotic lesions.
    As expression appeared higher in the epithelial endometrial layer, we performed
    a siRNA knockdown of LINC01133 in an endometriosis epithelial cell line. Phenotypic
    assays indicated that LINC01133 may promote proliferation and suppress cellular
    migration, and affect the cytoskeleton and morphology of the cells. Gene ontology
    analysis of differentially expressed genes indicated that cell proliferation and
    migration pathways were affected in line with the observed phenotype. We validated
    upregulation of p21 and downregulation of Cyclin A at the protein level, which
    together with the quantification of the DNA content using fluorescence-activated
    cell sorting (FACS) analysis indicated that the observed effects on cellular proliferation
    may be due to changes in cell cycle. Further, we found testis-specific protein
    kinase 1 (TESK1) kinase upregulation corresponding with phosphorylation and inactivation
    of actin severing protein Cofilin, which could explain changes in the cytoskeleton
    and cellular migration. These results indicate that endometriosis is associated
    with LINC01133 upregulation, which may affect pathogenesis via the cellular proliferation
    and migration pathways.
acknowledgement: "Open access funding provided by Medical University of Vienna. The
  authors would like to thank all the participants and health professionals involved
  in the present study. We want to thank our technical assistants Barbara Widmar and
  Matthias Witzmann-Stern for their diligent work and constant assistance. We would
  like to thank Simon Hippenmeyer for access to\r\nbioinformatic infrastructure and
  resources."
article_number: '8385'
article_processing_charge: Yes
article_type: original
author:
- first_name: Iveta
  full_name: Yotova, Iveta
  last_name: Yotova
- first_name: Quanah J.
  full_name: Hudson, Quanah J.
  last_name: Hudson
- first_name: Florian
  full_name: Pauler, Florian
  id: 48EA0138-F248-11E8-B48F-1D18A9856A87
  last_name: Pauler
  orcid: 0000-0002-7462-0048
- first_name: Katharina
  full_name: Proestling, Katharina
  last_name: Proestling
- first_name: Isabella
  full_name: Haslinger, Isabella
  last_name: Haslinger
- first_name: Lorenz
  full_name: Kuessel, Lorenz
  last_name: Kuessel
- first_name: Alexandra
  full_name: Perricos, Alexandra
  last_name: Perricos
- first_name: Heinrich
  full_name: Husslein, Heinrich
  last_name: Husslein
- first_name: René
  full_name: Wenzl, René
  last_name: Wenzl
citation:
  ama: Yotova I, Hudson QJ, Pauler F, et al. LINC01133 inhibits invasion and promotes
    proliferation in an endometriosis epithelial cell line. <i>International Journal
    of Molecular Sciences</i>. 2021;22(16). doi:<a href="https://doi.org/10.3390/ijms22168385">10.3390/ijms22168385</a>
  apa: Yotova, I., Hudson, Q. J., Pauler, F., Proestling, K., Haslinger, I., Kuessel,
    L., … Wenzl, R. (2021). LINC01133 inhibits invasion and promotes proliferation
    in an endometriosis epithelial cell line. <i>International Journal of Molecular
    Sciences</i>. MDPI. <a href="https://doi.org/10.3390/ijms22168385">https://doi.org/10.3390/ijms22168385</a>
  chicago: Yotova, Iveta, Quanah J. Hudson, Florian Pauler, Katharina Proestling,
    Isabella Haslinger, Lorenz Kuessel, Alexandra Perricos, Heinrich Husslein, and
    René Wenzl. “LINC01133 Inhibits Invasion and Promotes Proliferation in an Endometriosis
    Epithelial Cell Line.” <i>International Journal of Molecular Sciences</i>. MDPI,
    2021. <a href="https://doi.org/10.3390/ijms22168385">https://doi.org/10.3390/ijms22168385</a>.
  ieee: I. Yotova <i>et al.</i>, “LINC01133 inhibits invasion and promotes proliferation
    in an endometriosis epithelial cell line,” <i>International Journal of Molecular
    Sciences</i>, vol. 22, no. 16. MDPI, 2021.
  ista: Yotova I, Hudson QJ, Pauler F, Proestling K, Haslinger I, Kuessel L, Perricos
    A, Husslein H, Wenzl R. 2021. LINC01133 inhibits invasion and promotes proliferation
    in an endometriosis epithelial cell line. International Journal of Molecular Sciences.
    22(16), 8385.
  mla: Yotova, Iveta, et al. “LINC01133 Inhibits Invasion and Promotes Proliferation
    in an Endometriosis Epithelial Cell Line.” <i>International Journal of Molecular
    Sciences</i>, vol. 22, no. 16, 8385, MDPI, 2021, doi:<a href="https://doi.org/10.3390/ijms22168385">10.3390/ijms22168385</a>.
  short: I. Yotova, Q.J. Hudson, F. Pauler, K. Proestling, I. Haslinger, L. Kuessel,
    A. Perricos, H. Husslein, R. Wenzl, International Journal of Molecular Sciences
    22 (2021).
date_created: 2021-08-15T22:01:27Z
date_published: 2021-08-04T00:00:00Z
date_updated: 2023-08-11T10:34:13Z
day: '04'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.3390/ijms22168385
external_id:
  isi:
  - '000689147400001'
file:
- access_level: open_access
  checksum: be7f0042607ca60549cb27513c19c6af
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T09:29:17Z
  date_updated: 2021-08-16T09:29:17Z
  file_id: '9922'
  file_name: 2021_InternationalJournalOfMolecularSciences_Yotova.pdf
  file_size: 2646018
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T09:29:17Z
has_accepted_license: '1'
intvolume: '        22'
isi: 1
issue: '16'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: International Journal of Molecular Sciences
publication_identifier:
  eissn:
  - '14220067'
  issn:
  - '16616596'
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: LINC01133 inhibits invasion and promotes proliferation in an endometriosis
  epithelial cell line
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 22
year: '2021'
...
---
_id: '9907'
abstract:
- lang: eng
  text: 'DivIVA is a protein initially identified as a spatial regulator of cell division
    in the model organism Bacillus subtilis, but its homologues are present in many
    other Gram-positive bacteria, including Clostridia species. Besides its role as
    topological regulator of the Min system during bacterial cell division, DivIVA
    is involved in chromosome segregation during sporulation, genetic competence,
    and cell wall synthesis. DivIVA localizes to regions of high membrane curvature,
    such as the cell poles and cell division site, where it recruits distinct binding
    partners. Previously, it was suggested that negative curvature sensing is the
    main mechanism by which DivIVA binds to these specific regions. Here, we show
    that Clostridioides difficile DivIVA binds preferably to membranes containing
    negatively charged phospholipids, especially cardiolipin. Strikingly, we observed
    that upon binding, DivIVA modifies the lipid distribution and induces changes
    to lipid bilayers containing cardiolipin. Our observations indicate that DivIVA
    might play a more complex and so far unknown active role during the formation
    of the cell division septal membrane. '
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: "We thank Daniela Krajˇcíkova, Katarína Muchová, Zuzana Chromíkova
  and other members of Barák’s laboratory for useful discussions, suggestions and
  help. Special thanks also to Emília Chovancová for technical support. We are grateful
  to Juraj Labaj for drawing the model and for help with graphics. Many thanks to
  all members of Loose’s laboratory: Maria del Mar\r\nLópez, Paulo Caldas, Philipp
  Radler, and other members of the Loose’s laboratory for sharing their knowledge
  of SLB preparation and TIRF experiment chambers, for sharing coverslips and for
  help with the TIRF microscope and data analysis. We also thank the members of the
  Dept. of Biochemistry of Biomembranes at the Institute of Animal Biochemistry and
  Genetics, CBs SAS for their help with preparing the lipid mixtures. We thank J.
  Bauer for critically reading the manuscript."
article_number: '8350'
article_processing_charge: Yes
article_type: original
author:
- first_name: Naďa
  full_name: Labajová, Naďa
  last_name: Labajová
- first_name: Natalia S.
  full_name: Baranova, Natalia S.
  id: 38661662-F248-11E8-B48F-1D18A9856A87
  last_name: Baranova
  orcid: 0000-0002-3086-9124
- first_name: Miroslav
  full_name: Jurásek, Miroslav
  last_name: Jurásek
- first_name: Robert
  full_name: Vácha, Robert
  last_name: Vácha
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
- first_name: Imrich
  full_name: Barák, Imrich
  last_name: Barák
citation:
  ama: Labajová N, Baranova NS, Jurásek M, Vácha R, Loose M, Barák I. Cardiolipin-containing
    lipid membranes attract the bacterial cell division protein diviva. <i>International
    Journal of Molecular Sciences</i>. 2021;22(15). doi:<a href="https://doi.org/10.3390/ijms22158350">10.3390/ijms22158350</a>
  apa: Labajová, N., Baranova, N. S., Jurásek, M., Vácha, R., Loose, M., &#38; Barák,
    I. (2021). Cardiolipin-containing lipid membranes attract the bacterial cell division
    protein diviva. <i>International Journal of Molecular Sciences</i>. MDPI. <a href="https://doi.org/10.3390/ijms22158350">https://doi.org/10.3390/ijms22158350</a>
  chicago: Labajová, Naďa, Natalia S. Baranova, Miroslav Jurásek, Robert Vácha, Martin
    Loose, and Imrich Barák. “Cardiolipin-Containing Lipid Membranes Attract the Bacterial
    Cell Division Protein Diviva.” <i>International Journal of Molecular Sciences</i>.
    MDPI, 2021. <a href="https://doi.org/10.3390/ijms22158350">https://doi.org/10.3390/ijms22158350</a>.
  ieee: N. Labajová, N. S. Baranova, M. Jurásek, R. Vácha, M. Loose, and I. Barák,
    “Cardiolipin-containing lipid membranes attract the bacterial cell division protein
    diviva,” <i>International Journal of Molecular Sciences</i>, vol. 22, no. 15.
    MDPI, 2021.
  ista: Labajová N, Baranova NS, Jurásek M, Vácha R, Loose M, Barák I. 2021. Cardiolipin-containing
    lipid membranes attract the bacterial cell division protein diviva. International
    Journal of Molecular Sciences. 22(15), 8350.
  mla: Labajová, Naďa, et al. “Cardiolipin-Containing Lipid Membranes Attract the
    Bacterial Cell Division Protein Diviva.” <i>International Journal of Molecular
    Sciences</i>, vol. 22, no. 15, 8350, MDPI, 2021, doi:<a href="https://doi.org/10.3390/ijms22158350">10.3390/ijms22158350</a>.
  short: N. Labajová, N.S. Baranova, M. Jurásek, R. Vácha, M. Loose, I. Barák, International
    Journal of Molecular Sciences 22 (2021).
date_created: 2021-08-15T22:01:27Z
date_published: 2021-08-01T00:00:00Z
date_updated: 2023-08-11T10:34:44Z
day: '01'
ddc:
- '570'
department:
- _id: MaLo
doi: 10.3390/ijms22158350
ec_funded: 1
external_id:
  isi:
  - '000681815400001'
  pmid:
  - '34361115'
file:
- access_level: open_access
  checksum: a4bc06e9a2c803ceff5a91f10b174054
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T09:35:56Z
  date_updated: 2021-08-16T09:35:56Z
  file_id: '9923'
  file_name: 2021_InternationalJournalOfMolecularSciences_Labajová .pdf
  file_size: 6132410
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T09:35:56Z
has_accepted_license: '1'
intvolume: '        22'
isi: 1
issue: '15'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2595697A-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '679239'
  name: Self-Organization of the Bacterial Cell
publication: International Journal of Molecular Sciences
publication_identifier:
  eissn:
  - '14220067'
  issn:
  - '16616596'
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cardiolipin-containing lipid membranes attract the bacterial cell division
  protein diviva
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 22
year: '2021'
...
---
_id: '9908'
abstract:
- lang: eng
  text: About eight million animal species are estimated to live on Earth, and all
    except those belonging to one subphylum are invertebrates. Invertebrates are incredibly
    diverse in their morphologies, life histories, and in the range of the ecological
    niches that they occupy. A great variety of modes of reproduction and sex determination
    systems is also observed among them, and their mosaic-distribution across the
    phylogeny shows that transitions between them occur frequently and rapidly. Genetic
    conflict in its various forms is a long-standing theory to explain what drives
    those evolutionary transitions. Here, we review (1) the different modes of reproduction
    among invertebrate species, highlighting sexual reproduction as the probable ancestral
    state; (2) the paradoxical diversity of sex determination systems; (3) the different
    types of genetic conflicts that could drive the evolution of such different systems.
article_number: '1136'
article_processing_charge: Yes
article_type: review
author:
- first_name: Marion A L
  full_name: Picard, Marion A L
  id: 2C921A7A-F248-11E8-B48F-1D18A9856A87
  last_name: Picard
  orcid: 0000-0002-8101-2518
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
- first_name: Stéphanie
  full_name: Bertrand, Stéphanie
  last_name: Bertrand
- first_name: Hector
  full_name: Escriva, Hector
  last_name: Escriva
citation:
  ama: Picard MAL, Vicoso B, Bertrand S, Escriva H. Diversity of modes of reproduction
    and sex determination systems in invertebrates, and the putative contribution
    of genetic conflict. <i>Genes</i>. 2021;12(8). doi:<a href="https://doi.org/10.3390/genes12081136">10.3390/genes12081136</a>
  apa: Picard, M. A. L., Vicoso, B., Bertrand, S., &#38; Escriva, H. (2021). Diversity
    of modes of reproduction and sex determination systems in invertebrates, and the
    putative contribution of genetic conflict. <i>Genes</i>. MDPI. <a href="https://doi.org/10.3390/genes12081136">https://doi.org/10.3390/genes12081136</a>
  chicago: Picard, Marion A L, Beatriz Vicoso, Stéphanie Bertrand, and Hector Escriva.
    “Diversity of Modes of Reproduction and Sex Determination Systems in Invertebrates,
    and the Putative Contribution of Genetic Conflict.” <i>Genes</i>. MDPI, 2021.
    <a href="https://doi.org/10.3390/genes12081136">https://doi.org/10.3390/genes12081136</a>.
  ieee: M. A. L. Picard, B. Vicoso, S. Bertrand, and H. Escriva, “Diversity of modes
    of reproduction and sex determination systems in invertebrates, and the putative
    contribution of genetic conflict,” <i>Genes</i>, vol. 12, no. 8. MDPI, 2021.
  ista: Picard MAL, Vicoso B, Bertrand S, Escriva H. 2021. Diversity of modes of reproduction
    and sex determination systems in invertebrates, and the putative contribution
    of genetic conflict. Genes. 12(8), 1136.
  mla: Picard, Marion A. L., et al. “Diversity of Modes of Reproduction and Sex Determination
    Systems in Invertebrates, and the Putative Contribution of Genetic Conflict.”
    <i>Genes</i>, vol. 12, no. 8, 1136, MDPI, 2021, doi:<a href="https://doi.org/10.3390/genes12081136">10.3390/genes12081136</a>.
  short: M.A.L. Picard, B. Vicoso, S. Bertrand, H. Escriva, Genes 12 (2021).
date_created: 2021-08-15T22:01:27Z
date_published: 2021-08-01T00:00:00Z
date_updated: 2023-08-11T10:42:32Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.3390/genes12081136
ec_funded: 1
external_id:
  isi:
  - '000690475900001'
file:
- access_level: open_access
  checksum: 744e60e56d290a96da3c91a9779f886f
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T09:49:35Z
  date_updated: 2021-08-16T09:49:35Z
  file_id: '9926'
  file_name: 2021_Genes_Picard.pdf
  file_size: 2297655
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T09:49:35Z
has_accepted_license: '1'
intvolume: '        12'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 250BDE62-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '715257'
  name: Prevalence and Influence of Sexual Antagonism on Genome Evolution
publication: Genes
publication_identifier:
  eissn:
  - '20734425'
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Diversity of modes of reproduction and sex determination systems in invertebrates,
  and the putative contribution of genetic conflict
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2021'
...
---
_id: '9909'
abstract:
- lang: eng
  text: Roots are composed of different root types and, in the dicotyledonous Arabidopsis,
    typically consist of a primary root that branches into lateral roots. Adventitious
    roots emerge from non-root tissue and are formed upon wounding or other types
    of abiotic stress. Here, we investigated adventitious root (AR) formation in Arabidopsis
    hypocotyls under conditions of altered abscisic acid (ABA) signaling. Exogenously
    applied ABA suppressed AR formation at 0.25 µM or higher doses. AR formation was
    less sensitive to the synthetic ABA analog pyrabactin (PB). However, PB was a
    more potent inhibitor at concentrations above 1 µM, suggesting that it was more
    selective in triggering a root inhibition response. Analysis of a series of phosphonamide
    and phosphonate pyrabactin analogs suggested that adventitious root formation
    and lateral root branching are differentially regulated by ABA signaling. ABA
    biosynthesis and signaling mutants affirmed a general inhibitory role of ABA and
    point to PYL1 and PYL2 as candidate ABA receptors that regulate AR inhibition.
acknowledgement: We thank S. Cutler (Riverside, USA) for providing the ABA biosynthesis
  mutants and ABA signaling mutants.
article_number: '1141'
article_processing_charge: Yes
article_type: original
author:
- first_name: Yinwei
  full_name: Zeng, Yinwei
  last_name: Zeng
- first_name: Inge
  full_name: Verstraeten, Inge
  id: 362BF7FE-F248-11E8-B48F-1D18A9856A87
  last_name: Verstraeten
  orcid: 0000-0001-7241-2328
- first_name: Hoang Khai
  full_name: Trinh, Hoang Khai
  last_name: Trinh
- first_name: Thomas
  full_name: Heugebaert, Thomas
  last_name: Heugebaert
- first_name: Christian V.
  full_name: Stevens, Christian V.
  last_name: Stevens
- first_name: Irene
  full_name: Garcia-Maquilon, Irene
  last_name: Garcia-Maquilon
- first_name: Pedro L.
  full_name: Rodriguez, Pedro L.
  last_name: Rodriguez
- first_name: Steffen
  full_name: Vanneste, Steffen
  last_name: Vanneste
- first_name: Danny
  full_name: Geelen, Danny
  last_name: Geelen
citation:
  ama: Zeng Y, Verstraeten I, Trinh HK, et al. Arabidopsis hypocotyl adventitious
    root formation is suppressed by ABA signaling. <i>Genes</i>. 2021;12(8). doi:<a
    href="https://doi.org/10.3390/genes12081141">10.3390/genes12081141</a>
  apa: Zeng, Y., Verstraeten, I., Trinh, H. K., Heugebaert, T., Stevens, C. V., Garcia-Maquilon,
    I., … Geelen, D. (2021). Arabidopsis hypocotyl adventitious root formation is
    suppressed by ABA signaling. <i>Genes</i>. MDPI. <a href="https://doi.org/10.3390/genes12081141">https://doi.org/10.3390/genes12081141</a>
  chicago: Zeng, Yinwei, Inge Verstraeten, Hoang Khai Trinh, Thomas Heugebaert, Christian
    V. Stevens, Irene Garcia-Maquilon, Pedro L. Rodriguez, Steffen Vanneste, and Danny
    Geelen. “Arabidopsis Hypocotyl Adventitious Root Formation Is Suppressed by ABA
    Signaling.” <i>Genes</i>. MDPI, 2021. <a href="https://doi.org/10.3390/genes12081141">https://doi.org/10.3390/genes12081141</a>.
  ieee: Y. Zeng <i>et al.</i>, “Arabidopsis hypocotyl adventitious root formation
    is suppressed by ABA signaling,” <i>Genes</i>, vol. 12, no. 8. MDPI, 2021.
  ista: Zeng Y, Verstraeten I, Trinh HK, Heugebaert T, Stevens CV, Garcia-Maquilon
    I, Rodriguez PL, Vanneste S, Geelen D. 2021. Arabidopsis hypocotyl adventitious
    root formation is suppressed by ABA signaling. Genes. 12(8), 1141.
  mla: Zeng, Yinwei, et al. “Arabidopsis Hypocotyl Adventitious Root Formation Is
    Suppressed by ABA Signaling.” <i>Genes</i>, vol. 12, no. 8, 1141, MDPI, 2021,
    doi:<a href="https://doi.org/10.3390/genes12081141">10.3390/genes12081141</a>.
  short: Y. Zeng, I. Verstraeten, H.K. Trinh, T. Heugebaert, C.V. Stevens, I. Garcia-Maquilon,
    P.L. Rodriguez, S. Vanneste, D. Geelen, Genes 12 (2021).
date_created: 2021-08-15T22:01:28Z
date_published: 2021-07-27T00:00:00Z
date_updated: 2023-08-11T10:32:21Z
day: '27'
ddc:
- '580'
- '570'
department:
- _id: JiFr
doi: 10.3390/genes12081141
external_id:
  isi:
  - '000690558000001'
file:
- access_level: open_access
  checksum: 3d99535618cf9a5b14d264408fa52e97
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T09:02:40Z
  date_updated: 2021-08-16T09:02:40Z
  file_id: '9919'
  file_name: 2021_Genes_Zeng.pdf
  file_size: 1340305
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T09:02:40Z
has_accepted_license: '1'
intvolume: '        12'
isi: 1
issue: '8'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Genes
publication_identifier:
  eissn:
  - '20734425'
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Arabidopsis hypocotyl adventitious root formation is suppressed by ABA signaling
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2021'
...
---
_id: '9910'
abstract:
- lang: eng
  text: Adult height inspired the first biometrical and quantitative genetic studies
    and is a test-case trait for understanding heritability. The studies of height
    led to formulation of the classical polygenic model, that has a profound influence
    on the way we view and analyse complex traits. An essential part of the classical
    model is an assumption of additivity of effects and normality of the distribution
    of the residuals. However, it may be expected that the normal approximation will
    become insufficient in bigger studies. Here, we demonstrate that when the height
    of hundreds of thousands of individuals is analysed, the model complexity needs
    to be increased to include non-additive interactions between sex, environment
    and genes. Alternatively, the use of log-normal approximation allowed us to still
    use the additive effects model. These findings are important for future genetic
    and methodologic studies that make use of adult height as an exemplar trait.
acknowledgement: "We are grateful to Marianna Bevova and Pavel Borodin for fruitful
  discussion and help with conceptualising our findings and to Lennart C. Karssen
  for help with handling the UK Biobank data.\r\n\r\nFunding\r\nThis research has
  been conducted using the UK Biobank Resource (project # 41601, “Non-additive effects
  in control of complex human traits”). The work of SAS, IAK, and TIS were supported
  by Russian Ministry of Science and Education under the 5–100 Excellence Programme.
  The work of YSA and TIA was supported by the Ministry of Education and Science of
  the RF via the Institute of Cytology and Genetics SB RAS (project number 0324-2019-0040-C-01/AAAA-A17-117092070032-4).
  FAK is supported by the ERC Consolidator Grant (ChrFL: 771209)."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Sergei A.
  full_name: Slavskii, Sergei A.
  last_name: Slavskii
- first_name: Ivan A.
  full_name: Kuznetsov, Ivan A.
  last_name: Kuznetsov
- first_name: Tatiana I.
  full_name: Shashkova, Tatiana I.
  last_name: Shashkova
- first_name: Georgii A.
  full_name: Bazykin, Georgii A.
  last_name: Bazykin
- first_name: Tatiana I.
  full_name: Axenovich, Tatiana I.
  last_name: Axenovich
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Yurii S.
  full_name: Aulchenko, Yurii S.
  last_name: Aulchenko
citation:
  ama: Slavskii SA, Kuznetsov IA, Shashkova TI, et al. The limits of normal approximation
    for adult height. <i>European Journal of Human Genetics</i>. 2021;29(7):1082-1091.
    doi:<a href="https://doi.org/10.1038/s41431-021-00836-7">10.1038/s41431-021-00836-7</a>
  apa: Slavskii, S. A., Kuznetsov, I. A., Shashkova, T. I., Bazykin, G. A., Axenovich,
    T. I., Kondrashov, F., &#38; Aulchenko, Y. S. (2021). The limits of normal approximation
    for adult height. <i>European Journal of Human Genetics</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41431-021-00836-7">https://doi.org/10.1038/s41431-021-00836-7</a>
  chicago: Slavskii, Sergei A., Ivan A. Kuznetsov, Tatiana I. Shashkova, Georgii A.
    Bazykin, Tatiana I. Axenovich, Fyodor Kondrashov, and Yurii S. Aulchenko. “The
    Limits of Normal Approximation for Adult Height.” <i>European Journal of Human
    Genetics</i>. Springer Nature, 2021. <a href="https://doi.org/10.1038/s41431-021-00836-7">https://doi.org/10.1038/s41431-021-00836-7</a>.
  ieee: S. A. Slavskii <i>et al.</i>, “The limits of normal approximation for adult
    height,” <i>European Journal of Human Genetics</i>, vol. 29, no. 7. Springer Nature,
    pp. 1082–1091, 2021.
  ista: Slavskii SA, Kuznetsov IA, Shashkova TI, Bazykin GA, Axenovich TI, Kondrashov
    F, Aulchenko YS. 2021. The limits of normal approximation for adult height. European
    Journal of Human Genetics. 29(7), 1082–1091.
  mla: Slavskii, Sergei A., et al. “The Limits of Normal Approximation for Adult Height.”
    <i>European Journal of Human Genetics</i>, vol. 29, no. 7, Springer Nature, 2021,
    pp. 1082–91, doi:<a href="https://doi.org/10.1038/s41431-021-00836-7">10.1038/s41431-021-00836-7</a>.
  short: S.A. Slavskii, I.A. Kuznetsov, T.I. Shashkova, G.A. Bazykin, T.I. Axenovich,
    F. Kondrashov, Y.S. Aulchenko, European Journal of Human Genetics 29 (2021) 1082–1091.
date_created: 2021-08-15T22:01:28Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2023-08-11T10:33:42Z
day: '01'
ddc:
- '576'
department:
- _id: FyKo
doi: 10.1038/s41431-021-00836-7
ec_funded: 1
external_id:
  isi:
  - '000625853200001'
  pmid:
  - '33664501'
file:
- access_level: open_access
  checksum: a676d76f91b0dbe0504c63e469129c2a
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T09:14:36Z
  date_updated: 2021-08-16T09:14:36Z
  file_id: '9921'
  file_name: 2021_EuropeanJournalOfHumanGenetics_Slavskii.pdf
  file_size: 1079395
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T09:14:36Z
has_accepted_license: '1'
intvolume: '        29'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1082-1091
pmid: 1
project:
- _id: 26580278-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '771209'
  name: Characterizing the fitness landscape on population and global scales
publication: European Journal of Human Genetics
publication_identifier:
  eissn:
  - '14765438'
  issn:
  - '10184813'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The limits of normal approximation for adult height
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 29
year: '2021'
...
---
_id: '9911'
abstract:
- lang: eng
  text: A modern day light microscope has evolved from a tool devoted to making primarily
    empirical observations to what is now a sophisticated , quantitative device that
    is an integral part of both physical and life science research. Nowadays, microscopes
    are found in nearly every experimental laboratory. However, despite their prevalent
    use in capturing and quantifying scientific phenomena, neither a thorough understanding
    of the principles underlying quantitative imaging techniques nor appropriate knowledge
    of how to calibrate, operate and maintain microscopes can be taken for granted.
    This is clearly demonstrated by the well-documented and widespread difficulties
    that are routinely encountered in evaluating acquired data and reproducing scientific
    experiments. Indeed, studies have shown that more than 70% of researchers have
    tried and failed to repeat another scientist's experiments, while more than half
    have even failed to reproduce their own experiments. One factor behind the reproducibility
    crisis of experiments published in scientific journals is the frequent underreporting
    of imaging methods caused by a lack of awareness and/or a lack of knowledge of
    the applied technique. Whereas quality control procedures for some methods used
    in biomedical research, such as genomics (e.g. DNA sequencing, RNA-seq) or cytometry,
    have been introduced (e.g. ENCODE), this issue has not been tackled for optical
    microscopy instrumentation and images. Although many calibration standards and
    protocols have been published, there is a lack of awareness and agreement on common
    standards and guidelines for quality assessment and reproducibility. In April
    2020, the QUality Assessment and REProducibility for instruments and images in
    Light Microscopy (QUAREP-LiMi) initiative was formed. This initiative comprises
    imaging scientists from academia and industry who share a common interest in achieving
    a better understanding of the performance and limitations of microscopes and improved
    quality control (QC) in light microscopy. The ultimate goal of the QUAREP-LiMi
    initiative is to establish a set of common QC standards, guidelines, metadata
    models and tools, including detailed protocols, with the ultimate aim of improving
    reproducible advances in scientific research. This White Paper (1) summarizes
    the major obstacles identified in the field that motivated the launch of the QUAREP-LiMi
    initiative; (2) identifies the urgent need to address these obstacles in a grassroots
    manner, through a community of stakeholders including, researchers, imaging scientists,
    bioimage analysts, bioimage informatics developers, corporate partners, funding
    agencies, standards organizations, scientific publishers and observers of such;
    (3) outlines the current actions of the QUAREP-LiMi initiative and (4) proposes
    future steps that can be taken to improve the dissemination and acceptance of
    the proposed guidelines to manage QC. To summarize, the principal goal of the
    QUAREP-LiMi initiative is to improve the overall quality and reproducibility of
    light microscope image data by introducing broadly accepted standard practices
    and accurately captured image data metrics.
acknowledgement: We thank https://www.somersault1824.com/somersault18:24 BV (Leuven,
  Belgium) for help with Figure 1. E. C.-S. was supported by the project PPBI-POCI-01-0145-FEDER-022122,
  in the scope of Fundação para a Ciência e Tecnologia, Portugal (FCT) National Roadmap
  of Research Infrastructures. R.N. was funded by the Deutsche Forschungsgemeinschaft
  (DFG, German Research Foundation) Grant number Ni 451/9-1 - MIAP-Freiburg.
article_processing_charge: Yes
article_type: original
author:
- first_name: Glyn
  full_name: Nelson, Glyn
  last_name: Nelson
- first_name: Ulrike
  full_name: Boehm, Ulrike
  last_name: Boehm
- first_name: Steve
  full_name: Bagley, Steve
  last_name: Bagley
- first_name: Peter
  full_name: Bajcsy, Peter
  last_name: Bajcsy
- first_name: Johanna
  full_name: Bischof, Johanna
  last_name: Bischof
- first_name: Claire M.
  full_name: Brown, Claire M.
  last_name: Brown
- first_name: Aurélien
  full_name: Dauphin, Aurélien
  last_name: Dauphin
- first_name: Ian M.
  full_name: Dobbie, Ian M.
  last_name: Dobbie
- first_name: John E.
  full_name: Eriksson, John E.
  last_name: Eriksson
- first_name: Orestis
  full_name: Faklaris, Orestis
  last_name: Faklaris
- first_name: Julia
  full_name: Fernandez-Rodriguez, Julia
  last_name: Fernandez-Rodriguez
- first_name: Alexia
  full_name: Ferrand, Alexia
  last_name: Ferrand
- first_name: Laurent
  full_name: Gelman, Laurent
  last_name: Gelman
- first_name: Ali
  full_name: Gheisari, Ali
  last_name: Gheisari
- first_name: Hella
  full_name: Hartmann, Hella
  last_name: Hartmann
- first_name: Christian
  full_name: Kukat, Christian
  last_name: Kukat
- first_name: Alex
  full_name: Laude, Alex
  last_name: Laude
- first_name: Miso
  full_name: Mitkovski, Miso
  last_name: Mitkovski
- first_name: Sebastian
  full_name: Munck, Sebastian
  last_name: Munck
- first_name: Alison J.
  full_name: North, Alison J.
  last_name: North
- first_name: Tobias M.
  full_name: Rasse, Tobias M.
  last_name: Rasse
- first_name: Ute
  full_name: Resch-Genger, Ute
  last_name: Resch-Genger
- first_name: Lucas C.
  full_name: Schuetz, Lucas C.
  last_name: Schuetz
- first_name: Arne
  full_name: Seitz, Arne
  last_name: Seitz
- first_name: Caterina
  full_name: Strambio-De-Castillia, Caterina
  last_name: Strambio-De-Castillia
- first_name: Jason R.
  full_name: Swedlow, Jason R.
  last_name: Swedlow
- first_name: Ioannis
  full_name: Alexopoulos, Ioannis
  last_name: Alexopoulos
- first_name: Karin
  full_name: Aumayr, Karin
  last_name: Aumayr
- first_name: Sergiy
  full_name: Avilov, Sergiy
  last_name: Avilov
- first_name: Gert Jan
  full_name: Bakker, Gert Jan
  last_name: Bakker
- first_name: Rodrigo R.
  full_name: Bammann, Rodrigo R.
  last_name: Bammann
- first_name: Andrea
  full_name: Bassi, Andrea
  last_name: Bassi
- first_name: Hannes
  full_name: Beckert, Hannes
  last_name: Beckert
- first_name: Sebastian
  full_name: Beer, Sebastian
  last_name: Beer
- first_name: Yury
  full_name: Belyaev, Yury
  last_name: Belyaev
- first_name: Jakob
  full_name: Bierwagen, Jakob
  last_name: Bierwagen
- first_name: Konstantin A.
  full_name: Birngruber, Konstantin A.
  last_name: Birngruber
- first_name: Manel
  full_name: Bosch, Manel
  last_name: Bosch
- first_name: Juergen
  full_name: Breitlow, Juergen
  last_name: Breitlow
- first_name: Lisa A.
  full_name: Cameron, Lisa A.
  last_name: Cameron
- first_name: Joe
  full_name: Chalfoun, Joe
  last_name: Chalfoun
- first_name: James J.
  full_name: Chambers, James J.
  last_name: Chambers
- first_name: Chieh Li
  full_name: Chen, Chieh Li
  last_name: Chen
- first_name: Eduardo
  full_name: Conde-Sousa, Eduardo
  last_name: Conde-Sousa
- first_name: Alexander D.
  full_name: Corbett, Alexander D.
  last_name: Corbett
- first_name: Fabrice P.
  full_name: Cordelieres, Fabrice P.
  last_name: Cordelieres
- first_name: Elaine Del
  full_name: Nery, Elaine Del
  last_name: Nery
- first_name: Ralf
  full_name: Dietzel, Ralf
  last_name: Dietzel
- first_name: Frank
  full_name: Eismann, Frank
  last_name: Eismann
- first_name: Elnaz
  full_name: Fazeli, Elnaz
  last_name: Fazeli
- first_name: Andreas
  full_name: Felscher, Andreas
  last_name: Felscher
- first_name: Hans
  full_name: Fried, Hans
  last_name: Fried
- first_name: Nathalie
  full_name: Gaudreault, Nathalie
  last_name: Gaudreault
- first_name: Wah Ing
  full_name: Goh, Wah Ing
  last_name: Goh
- first_name: Thomas
  full_name: Guilbert, Thomas
  last_name: Guilbert
- first_name: Roland
  full_name: Hadleigh, Roland
  last_name: Hadleigh
- first_name: Peter
  full_name: Hemmerich, Peter
  last_name: Hemmerich
- first_name: Gerhard A.
  full_name: Holst, Gerhard A.
  last_name: Holst
- first_name: Michelle S.
  full_name: Itano, Michelle S.
  last_name: Itano
- first_name: Claudia B.
  full_name: Jaffe, Claudia B.
  last_name: Jaffe
- first_name: Helena K.
  full_name: Jambor, Helena K.
  last_name: Jambor
- first_name: Stuart C.
  full_name: Jarvis, Stuart C.
  last_name: Jarvis
- first_name: Antje
  full_name: Keppler, Antje
  last_name: Keppler
- first_name: David
  full_name: Kirchenbuechler, David
  last_name: Kirchenbuechler
- first_name: Marcel
  full_name: Kirchner, Marcel
  last_name: Kirchner
- first_name: Norio
  full_name: Kobayashi, Norio
  last_name: Kobayashi
- first_name: Gabriel
  full_name: Krens, Gabriel
  id: 2B819732-F248-11E8-B48F-1D18A9856A87
  last_name: Krens
  orcid: 0000-0003-4761-5996
- first_name: Susanne
  full_name: Kunis, Susanne
  last_name: Kunis
- first_name: Judith
  full_name: Lacoste, Judith
  last_name: Lacoste
- first_name: Marco
  full_name: Marcello, Marco
  last_name: Marcello
- first_name: Gabriel G.
  full_name: Martins, Gabriel G.
  last_name: Martins
- first_name: Daniel J.
  full_name: Metcalf, Daniel J.
  last_name: Metcalf
- first_name: Claire A.
  full_name: Mitchell, Claire A.
  last_name: Mitchell
- first_name: Joshua
  full_name: Moore, Joshua
  last_name: Moore
- first_name: Tobias
  full_name: Mueller, Tobias
  last_name: Mueller
- first_name: Michael S.
  full_name: Nelson, Michael S.
  last_name: Nelson
- first_name: Stephen
  full_name: Ogg, Stephen
  last_name: Ogg
- first_name: Shuichi
  full_name: Onami, Shuichi
  last_name: Onami
- first_name: Alexandra L.
  full_name: Palmer, Alexandra L.
  last_name: Palmer
- first_name: Perrine
  full_name: Paul-Gilloteaux, Perrine
  last_name: Paul-Gilloteaux
- first_name: Jaime A.
  full_name: Pimentel, Jaime A.
  last_name: Pimentel
- first_name: Laure
  full_name: Plantard, Laure
  last_name: Plantard
- first_name: Santosh
  full_name: Podder, Santosh
  last_name: Podder
- first_name: Elton
  full_name: Rexhepaj, Elton
  last_name: Rexhepaj
- first_name: Arnaud
  full_name: Royon, Arnaud
  last_name: Royon
- first_name: Markku A.
  full_name: Saari, Markku A.
  last_name: Saari
- first_name: Damien
  full_name: Schapman, Damien
  last_name: Schapman
- first_name: Vincent
  full_name: Schoonderwoert, Vincent
  last_name: Schoonderwoert
- first_name: Britta
  full_name: Schroth-Diez, Britta
  last_name: Schroth-Diez
- first_name: Stanley
  full_name: Schwartz, Stanley
  last_name: Schwartz
- first_name: Michael
  full_name: Shaw, Michael
  last_name: Shaw
- first_name: Martin
  full_name: Spitaler, Martin
  last_name: Spitaler
- first_name: Martin T.
  full_name: Stoeckl, Martin T.
  last_name: Stoeckl
- first_name: Damir
  full_name: Sudar, Damir
  last_name: Sudar
- first_name: Jeremie
  full_name: Teillon, Jeremie
  last_name: Teillon
- first_name: Stefan
  full_name: Terjung, Stefan
  last_name: Terjung
- first_name: Roland
  full_name: Thuenauer, Roland
  last_name: Thuenauer
- first_name: Christian D.
  full_name: Wilms, Christian D.
  last_name: Wilms
- first_name: Graham D.
  full_name: Wright, Graham D.
  last_name: Wright
- first_name: Roland
  full_name: Nitschke, Roland
  last_name: Nitschke
citation:
  ama: 'Nelson G, Boehm U, Bagley S, et al. QUAREP-LiMi: A community-driven initiative
    to establish guidelines for quality assessment and reproducibility for instruments
    and images in light microscopy. <i>Journal of Microscopy</i>. 2021;284(1):56-73.
    doi:<a href="https://doi.org/10.1111/jmi.13041">10.1111/jmi.13041</a>'
  apa: 'Nelson, G., Boehm, U., Bagley, S., Bajcsy, P., Bischof, J., Brown, C. M.,
    … Nitschke, R. (2021). QUAREP-LiMi: A community-driven initiative to establish
    guidelines for quality assessment and reproducibility for instruments and images
    in light microscopy. <i>Journal of Microscopy</i>. Wiley. <a href="https://doi.org/10.1111/jmi.13041">https://doi.org/10.1111/jmi.13041</a>'
  chicago: 'Nelson, Glyn, Ulrike Boehm, Steve Bagley, Peter Bajcsy, Johanna Bischof,
    Claire M. Brown, Aurélien Dauphin, et al. “QUAREP-LiMi: A Community-Driven Initiative
    to Establish Guidelines for Quality Assessment and Reproducibility for Instruments
    and Images in Light Microscopy.” <i>Journal of Microscopy</i>. Wiley, 2021. <a
    href="https://doi.org/10.1111/jmi.13041">https://doi.org/10.1111/jmi.13041</a>.'
  ieee: 'G. Nelson <i>et al.</i>, “QUAREP-LiMi: A community-driven initiative to establish
    guidelines for quality assessment and reproducibility for instruments and images
    in light microscopy,” <i>Journal of Microscopy</i>, vol. 284, no. 1. Wiley, pp.
    56–73, 2021.'
  ista: 'Nelson G et al. 2021. QUAREP-LiMi: A community-driven initiative to establish
    guidelines for quality assessment and reproducibility for instruments and images
    in light microscopy. Journal of Microscopy. 284(1), 56–73.'
  mla: 'Nelson, Glyn, et al. “QUAREP-LiMi: A Community-Driven Initiative to Establish
    Guidelines for Quality Assessment and Reproducibility for Instruments and Images
    in Light Microscopy.” <i>Journal of Microscopy</i>, vol. 284, no. 1, Wiley, 2021,
    pp. 56–73, doi:<a href="https://doi.org/10.1111/jmi.13041">10.1111/jmi.13041</a>.'
  short: G. Nelson, U. Boehm, S. Bagley, P. Bajcsy, J. Bischof, C.M. Brown, A. Dauphin,
    I.M. Dobbie, J.E. Eriksson, O. Faklaris, J. Fernandez-Rodriguez, A. Ferrand, L.
    Gelman, A. Gheisari, H. Hartmann, C. Kukat, A. Laude, M. Mitkovski, S. Munck,
    A.J. North, T.M. Rasse, U. Resch-Genger, L.C. Schuetz, A. Seitz, C. Strambio-De-Castillia,
    J.R. Swedlow, I. Alexopoulos, K. Aumayr, S. Avilov, G.J. Bakker, R.R. Bammann,
    A. Bassi, H. Beckert, S. Beer, Y. Belyaev, J. Bierwagen, K.A. Birngruber, M. Bosch,
    J. Breitlow, L.A. Cameron, J. Chalfoun, J.J. Chambers, C.L. Chen, E. Conde-Sousa,
    A.D. Corbett, F.P. Cordelieres, E.D. Nery, R. Dietzel, F. Eismann, E. Fazeli,
    A. Felscher, H. Fried, N. Gaudreault, W.I. Goh, T. Guilbert, R. Hadleigh, P. Hemmerich,
    G.A. Holst, M.S. Itano, C.B. Jaffe, H.K. Jambor, S.C. Jarvis, A. Keppler, D. Kirchenbuechler,
    M. Kirchner, N. Kobayashi, G. Krens, S. Kunis, J. Lacoste, M. Marcello, G.G. Martins,
    D.J. Metcalf, C.A. Mitchell, J. Moore, T. Mueller, M.S. Nelson, S. Ogg, S. Onami,
    A.L. Palmer, P. Paul-Gilloteaux, J.A. Pimentel, L. Plantard, S. Podder, E. Rexhepaj,
    A. Royon, M.A. Saari, D. Schapman, V. Schoonderwoert, B. Schroth-Diez, S. Schwartz,
    M. Shaw, M. Spitaler, M.T. Stoeckl, D. Sudar, J. Teillon, S. Terjung, R. Thuenauer,
    C.D. Wilms, G.D. Wright, R. Nitschke, Journal of Microscopy 284 (2021) 56–73.
date_created: 2021-08-15T22:01:29Z
date_published: 2021-08-11T00:00:00Z
date_updated: 2023-08-11T10:30:40Z
day: '11'
department:
- _id: Bio
doi: 10.1111/jmi.13041
external_id:
  isi:
  - '000683702700001'
intvolume: '       284'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1111/jmi.13041
month: '08'
oa: 1
oa_version: Published Version
page: 56-73
publication: Journal of Microscopy
publication_identifier:
  eissn:
  - 1365-2818
  issn:
  - 0022-2720
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'QUAREP-LiMi: A community-driven initiative to establish guidelines for quality
  assessment and reproducibility for instruments and images in light microscopy'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 284
year: '2021'
...
---
_id: '9912'
abstract:
- lang: eng
  text: "In the customary random matrix model for transport in quantum dots with M
    internal degrees of freedom coupled to a chaotic environment via \U0001D441≪\U0001D440
    channels, the density \U0001D70C of transmission eigenvalues is computed from
    a specific invariant ensemble for which explicit formula for the joint probability
    density of all eigenvalues is available. We revisit this problem in the large
    N regime allowing for (i) arbitrary ratio \U0001D719:=\U0001D441/\U0001D440≤1;
    and (ii) general distributions for the matrix elements of the Hamiltonian of the
    quantum dot. In the limit \U0001D719→0, we recover the formula for the density
    \U0001D70C that Beenakker (Rev Mod Phys 69:731–808, 1997) has derived for a special
    matrix ensemble. We also prove that the inverse square root singularity of the
    density at zero and full transmission in Beenakker’s formula persists for any
    \U0001D719<1 but in the borderline case \U0001D719=1 an anomalous \U0001D706−2/3
    singularity arises at zero. To access this level of generality, we develop the
    theory of global and local laws on the spectral density of a large class of noncommutative
    rational expressions in large random matrices with i.i.d. entries."
acknowledgement: The authors are very grateful to Yan Fyodorov for discussions on
  the physical background and for providing references, and to the anonymous referee
  for numerous valuable remarks.
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Torben H
  full_name: Krüger, Torben H
  id: 3020C786-F248-11E8-B48F-1D18A9856A87
  last_name: Krüger
  orcid: 0000-0002-4821-3297
- first_name: Yuriy
  full_name: Nemish, Yuriy
  id: 4D902E6A-F248-11E8-B48F-1D18A9856A87
  last_name: Nemish
  orcid: 0000-0002-7327-856X
citation:
  ama: Erdös L, Krüger TH, Nemish Y. Scattering in quantum dots via noncommutative
    rational functions. <i>Annales Henri Poincaré </i>. 2021;22:4205–4269. doi:<a
    href="https://doi.org/10.1007/s00023-021-01085-6">10.1007/s00023-021-01085-6</a>
  apa: Erdös, L., Krüger, T. H., &#38; Nemish, Y. (2021). Scattering in quantum dots
    via noncommutative rational functions. <i>Annales Henri Poincaré </i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00023-021-01085-6">https://doi.org/10.1007/s00023-021-01085-6</a>
  chicago: Erdös, László, Torben H Krüger, and Yuriy Nemish. “Scattering in Quantum
    Dots via Noncommutative Rational Functions.” <i>Annales Henri Poincaré </i>. Springer
    Nature, 2021. <a href="https://doi.org/10.1007/s00023-021-01085-6">https://doi.org/10.1007/s00023-021-01085-6</a>.
  ieee: L. Erdös, T. H. Krüger, and Y. Nemish, “Scattering in quantum dots via noncommutative
    rational functions,” <i>Annales Henri Poincaré </i>, vol. 22. Springer Nature,
    pp. 4205–4269, 2021.
  ista: Erdös L, Krüger TH, Nemish Y. 2021. Scattering in quantum dots via noncommutative
    rational functions. Annales Henri Poincaré . 22, 4205–4269.
  mla: Erdös, László, et al. “Scattering in Quantum Dots via Noncommutative Rational
    Functions.” <i>Annales Henri Poincaré </i>, vol. 22, Springer Nature, 2021, pp.
    4205–4269, doi:<a href="https://doi.org/10.1007/s00023-021-01085-6">10.1007/s00023-021-01085-6</a>.
  short: L. Erdös, T.H. Krüger, Y. Nemish, Annales Henri Poincaré  22 (2021) 4205–4269.
date_created: 2021-08-15T22:01:29Z
date_published: 2021-12-01T00:00:00Z
date_updated: 2023-08-11T10:31:48Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1007/s00023-021-01085-6
ec_funded: 1
external_id:
  arxiv:
  - '1911.05112'
  isi:
  - '000681531500001'
file:
- access_level: open_access
  checksum: 8d6bac0e2b0a28539608b0538a8e3b38
  content_type: application/pdf
  creator: dernst
  date_created: 2022-05-12T12:50:27Z
  date_updated: 2022-05-12T12:50:27Z
  file_id: '11365'
  file_name: 2021_AnnHenriPoincare_Erdoes.pdf
  file_size: 1162454
  relation: main_file
  success: 1
file_date_updated: 2022-05-12T12:50:27Z
has_accepted_license: '1'
intvolume: '        22'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 4205–4269
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: 'Annales Henri Poincaré '
publication_identifier:
  eissn:
  - 1424-0661
  issn:
  - 1424-0637
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Scattering in quantum dots via noncommutative rational functions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 22
year: '2021'
...
---
_id: '9913'
abstract:
- lang: eng
  text: Nitrate commands genome-wide gene expression changes that impact metabolism,
    physiology, plant growth, and development. In an effort to identify new components
    involved in nitrate responses in plants, we analyze the Arabidopsis thaliana root
    phosphoproteome in response to nitrate treatments via liquid chromatography coupled
    to tandem mass spectrometry. 176 phosphoproteins show significant changes at 5
    or 20 min after nitrate treatments. Proteins identified by 5 min include signaling
    components such as kinases or transcription factors. In contrast, by 20 min, proteins
    identified were associated with transporter activity or hormone metabolism functions,
    among others. The phosphorylation profile of NITRATE TRANSPORTER 1.1 (NRT1.1)
    mutant plants was significantly altered as compared to wild-type plants, confirming
    its key role in nitrate signaling pathways that involves phosphorylation changes.
    Integrative bioinformatics analysis highlights auxin transport as an important
    mechanism modulated by nitrate signaling at the post-translational level. We validated
    a new phosphorylation site in PIN2 and provide evidence that it functions in primary
    and lateral root growth responses to nitrate.
acknowledgement: This work was supported by ANID—Millennium Science Initiative Program—ICN17_022,
  Fondo de Desarrollo de Areas Prioritarias (FONDAP) Center for Genome Regulation
  (15090007), ANID—Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT)
  1180759 (to RAG) and 1171631 (to AV). We would like to thank Unidad de Microscopía
  Avanzada UC (UMA UC).
article_number: e51813
article_processing_charge: Yes
article_type: original
author:
- first_name: Andrea
  full_name: Vega, Andrea
  last_name: Vega
- first_name: Isabel
  full_name: Fredes, Isabel
  last_name: Fredes
- first_name: José
  full_name: O’Brien, José
  last_name: O’Brien
- first_name: Zhouxin
  full_name: Shen, Zhouxin
  last_name: Shen
- first_name: Krisztina
  full_name: Ötvös, Krisztina
  id: 29B901B0-F248-11E8-B48F-1D18A9856A87
  last_name: Ötvös
  orcid: 0000-0002-5503-4983
- first_name: Rashed
  full_name: Abualia, Rashed
  id: 4827E134-F248-11E8-B48F-1D18A9856A87
  last_name: Abualia
  orcid: 0000-0002-9357-9415
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Steven P.
  full_name: Briggs, Steven P.
  last_name: Briggs
- first_name: Rodrigo A.
  full_name: Gutiérrez, Rodrigo A.
  last_name: Gutiérrez
citation:
  ama: Vega A, Fredes I, O’Brien J, et al. Nitrate triggered phosphoproteome changes
    and a PIN2 phosphosite modulating root system architecture. <i>EMBO Reports</i>.
    2021;22(9). doi:<a href="https://doi.org/10.15252/embr.202051813">10.15252/embr.202051813</a>
  apa: Vega, A., Fredes, I., O’Brien, J., Shen, Z., Ötvös, K., Abualia, R., … Gutiérrez,
    R. A. (2021). Nitrate triggered phosphoproteome changes and a PIN2 phosphosite
    modulating root system architecture. <i>EMBO Reports</i>. Wiley. <a href="https://doi.org/10.15252/embr.202051813">https://doi.org/10.15252/embr.202051813</a>
  chicago: Vega, Andrea, Isabel Fredes, José O’Brien, Zhouxin Shen, Krisztina Ötvös,
    Rashed Abualia, Eva Benková, Steven P. Briggs, and Rodrigo A. Gutiérrez. “Nitrate
    Triggered Phosphoproteome Changes and a PIN2 Phosphosite Modulating Root System
    Architecture.” <i>EMBO Reports</i>. Wiley, 2021. <a href="https://doi.org/10.15252/embr.202051813">https://doi.org/10.15252/embr.202051813</a>.
  ieee: A. Vega <i>et al.</i>, “Nitrate triggered phosphoproteome changes and a PIN2
    phosphosite modulating root system architecture,” <i>EMBO Reports</i>, vol. 22,
    no. 9. Wiley, 2021.
  ista: Vega A, Fredes I, O’Brien J, Shen Z, Ötvös K, Abualia R, Benková E, Briggs
    SP, Gutiérrez RA. 2021. Nitrate triggered phosphoproteome changes and a PIN2 phosphosite
    modulating root system architecture. EMBO Reports. 22(9), e51813.
  mla: Vega, Andrea, et al. “Nitrate Triggered Phosphoproteome Changes and a PIN2
    Phosphosite Modulating Root System Architecture.” <i>EMBO Reports</i>, vol. 22,
    no. 9, e51813, Wiley, 2021, doi:<a href="https://doi.org/10.15252/embr.202051813">10.15252/embr.202051813</a>.
  short: A. Vega, I. Fredes, J. O’Brien, Z. Shen, K. Ötvös, R. Abualia, E. Benková,
    S.P. Briggs, R.A. Gutiérrez, EMBO Reports 22 (2021).
date_created: 2021-08-15T22:01:30Z
date_published: 2021-09-06T00:00:00Z
date_updated: 2024-03-25T23:30:22Z
day: '06'
ddc:
- '580'
department:
- _id: EvBe
- _id: GradSch
doi: 10.15252/embr.202051813
external_id:
  isi:
  - '000681754200001'
  pmid:
  - '34357701 '
file:
- access_level: open_access
  checksum: 750de03dc3b715c37090126c1548ba13
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-10-05T13:36:42Z
  date_updated: 2021-10-05T13:36:42Z
  file_id: '10090'
  file_name: 2021_EmboR_Vega.pdf
  file_size: 3144854
  relation: main_file
  success: 1
file_date_updated: 2021-10-05T13:36:42Z
has_accepted_license: '1'
intvolume: '        22'
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issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: EMBO Reports
publication_identifier:
  eissn:
  - 1469-3178
  issn:
  - 1469-221X
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '10303'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Nitrate triggered phosphoproteome changes and a PIN2 phosphosite modulating
  root system architecture
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 22
year: '2021'
...
---
_id: '9920'
abstract:
- lang: eng
  text: 'This work is concerned with two fascinating circuit quantum electrodynamics
    components, the Josephson junction and the geometric superinductor, and the interesting
    experiments that can be done by combining the two. The Josephson junction has
    revolutionized the field of superconducting circuits as a non-linear dissipation-less
    circuit element and is used in almost all superconducting qubit implementations
    since the 90s. On the other hand, the superinductor is a relatively new circuit
    element introduced as a key component of the fluxonium qubit in 2009. This is
    an inductor with characteristic impedance larger than the resistance quantum and
    self-resonance frequency in the GHz regime. The combination of these two elements
    can occur in two fundamental ways: in parallel and in series. When connected in
    parallel the two create the fluxonium qubit, a loop with large inductance and
    a rich energy spectrum reliant on quantum tunneling. On the other hand placing
    the two elements in series aids with the measurement of the IV curve of a single
    Josephson junction in a high impedance environment. In this limit theory predicts
    that the junction will behave as its dual element: the phase-slip junction. While
    the Josephson junction acts as a non-linear inductor the phase-slip junction has
    the behavior of a non-linear capacitance and can be used to measure new Josephson
    junction phenomena, namely Coulomb blockade of Cooper pairs and phase-locked Bloch
    oscillations. The latter experiment allows for a direct link between frequency
    and current which is an elusive connection in quantum metrology. This work introduces
    the geometric superinductor, a superconducting circuit element where the high
    inductance is due to the geometry rather than the material properties of the superconductor,
    realized from a highly miniaturized superconducting planar coil. These structures
    will be described and characterized as resonators and qubit inductors and progress
    towards the measurement of phase-locked Bloch oscillations will be presented.'
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Matilda
  full_name: Peruzzo, Matilda
  id: 3F920B30-F248-11E8-B48F-1D18A9856A87
  last_name: Peruzzo
  orcid: 0000-0002-3415-4628
citation:
  ama: Peruzzo M. Geometric superinductors and their applications in circuit quantum
    electrodynamics. 2021. doi:<a href="https://doi.org/10.15479/at:ista:9920">10.15479/at:ista:9920</a>
  apa: Peruzzo, M. (2021). <i>Geometric superinductors and their applications in circuit
    quantum electrodynamics</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:9920">https://doi.org/10.15479/at:ista:9920</a>
  chicago: Peruzzo, Matilda. “Geometric Superinductors and Their Applications in Circuit
    Quantum Electrodynamics.” Institute of Science and Technology Austria, 2021. <a
    href="https://doi.org/10.15479/at:ista:9920">https://doi.org/10.15479/at:ista:9920</a>.
  ieee: M. Peruzzo, “Geometric superinductors and their applications in circuit quantum
    electrodynamics,” Institute of Science and Technology Austria, 2021.
  ista: Peruzzo M. 2021. Geometric superinductors and their applications in circuit
    quantum electrodynamics. Institute of Science and Technology Austria.
  mla: Peruzzo, Matilda. <i>Geometric Superinductors and Their Applications in Circuit
    Quantum Electrodynamics</i>. Institute of Science and Technology Austria, 2021,
    doi:<a href="https://doi.org/10.15479/at:ista:9920">10.15479/at:ista:9920</a>.
  short: M. Peruzzo, Geometric Superinductors and Their Applications in Circuit Quantum
    Electrodynamics, Institute of Science and Technology Austria, 2021.
date_created: 2021-08-16T09:44:09Z
date_published: 2021-08-19T00:00:00Z
date_updated: 2024-09-10T12:23:56Z
day: '19'
ddc:
- '539'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JoFi
doi: 10.15479/at:ista:9920
file:
- access_level: closed
  checksum: 3cd1986efde5121d7581f6fcf9090da8
  content_type: application/x-zip-compressed
  creator: mperuzzo
  date_created: 2021-08-16T09:33:21Z
  date_updated: 2021-09-06T08:39:47Z
  file_id: '9924'
  file_name: GeometricSuperinductorsForCQED.zip
  file_size: 151387283
  relation: source_file
- access_level: open_access
  checksum: 50928c621cdf0775d7a5906b9dc8602c
  content_type: application/pdf
  creator: mperuzzo
  date_created: 2021-08-18T14:20:06Z
  date_updated: 2021-09-06T08:39:47Z
  file_id: '9939'
  file_name: GeometricSuperinductorsAndTheirApplicationsIncQED-1b.pdf
  file_size: 17596344
  relation: main_file
- access_level: closed
  checksum: 37f486aa1b622fe44af00d627ec13f6c
  content_type: application/pdf
  creator: mperuzzo
  date_created: 2021-08-18T14:20:09Z
  date_updated: 2021-09-06T08:39:47Z
  description: Extra copy of the thesis as PDF/A-2b
  file_id: '9940'
  file_name: GeometricSuperinductorsAndTheirApplicationsIncQED-2b.pdf
  file_size: 17592425
  relation: other
file_date_updated: 2021-09-06T08:39:47Z
has_accepted_license: '1'
keyword:
- quantum computing
- superinductor
- quantum metrology
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '149'
publication_identifier:
  isbn:
  - 978-3-99078-013-8
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '9928'
    relation: part_of_dissertation
    status: public
  - id: '8755'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
title: Geometric superinductors and their applications in circuit quantum electrodynamics
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2021'
...
---
_id: '9928'
abstract:
- lang: eng
  text: There are two elementary superconducting qubit types that derive directly
    from the quantum harmonic oscillator. In one, the inductor is replaced by a nonlinear
    Josephson junction to realize the widely used charge qubits with a compact phase
    variable and a discrete charge wave function. In the other, the junction is added
    in parallel, which gives rise to an extended phase variable, continuous wave functions,
    and a rich energy-level structure due to the loop topology. While the corresponding
    rf superconducting quantum interference device Hamiltonian was introduced as a
    quadratic quasi-one-dimensional potential approximation to describe the fluxonium
    qubit implemented with long Josephson-junction arrays, in this work we implement
    it directly using a linear superinductor formed by a single uninterrupted aluminum
    wire. We present a large variety of qubits, all stemming from the same circuit
    but with drastically different characteristic energy scales. This includes flux
    and fluxonium qubits but also the recently introduced quasicharge qubit with strongly
    enhanced zero-point phase fluctuations and a heavily suppressed flux dispersion.
    The use of a geometric inductor results in high reproducibility of the inductive
    energy as guaranteed by top-down lithography—a key ingredient for intrinsically
    protected superconducting qubits.
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
acknowledgement: We thank W. Hughes for analytic and numerical modeling during the
  early stages of this work, J. Koch for discussions and support with the scqubits
  package, R. Sett, P. Zielinski, and L. Drmic for software development, and G. Katsaros
  for equipment support, as well as the MIBA workshop and the Institute of Science
  and Technology Austria nanofabrication facility. We thank I. Pop, S. Deleglise,
  and E. Flurin for discussions. This work was supported by a NOMIS Foundation research
  grant, the Austrian Science Fund (FWF) through BeyondC (F7105), and IST Austria.
  M.P. is the recipient of a Pöttinger scholarship at IST Austria. E.R. is the recipient
  of a DOC fellowship of the Austrian Academy of Sciences at IST Austria.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Matilda
  full_name: Peruzzo, Matilda
  id: 3F920B30-F248-11E8-B48F-1D18A9856A87
  last_name: Peruzzo
  orcid: 0000-0002-3415-4628
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Gregory
  full_name: Szep, Gregory
  last_name: Szep
- first_name: Andrea
  full_name: Trioni, Andrea
  id: 42F71B44-F248-11E8-B48F-1D18A9856A87
  last_name: Trioni
- first_name: Elena
  full_name: Redchenko, Elena
  id: 2C21D6E8-F248-11E8-B48F-1D18A9856A87
  last_name: Redchenko
- first_name: Martin
  full_name: Zemlicka, Martin
  id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
  last_name: Zemlicka
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: 'Peruzzo M, Hassani F, Szep G, et al. Geometric superinductance qubits: Controlling
    phase delocalization across a single Josephson junction. <i>PRX Quantum</i>. 2021;2(4):040341.
    doi:<a href="https://doi.org/10.1103/PRXQuantum.2.040341">10.1103/PRXQuantum.2.040341</a>'
  apa: 'Peruzzo, M., Hassani, F., Szep, G., Trioni, A., Redchenko, E., Zemlicka, M.,
    &#38; Fink, J. M. (2021). Geometric superinductance qubits: Controlling phase
    delocalization across a single Josephson junction. <i>PRX Quantum</i>. American
    Physical Society. <a href="https://doi.org/10.1103/PRXQuantum.2.040341">https://doi.org/10.1103/PRXQuantum.2.040341</a>'
  chicago: 'Peruzzo, Matilda, Farid Hassani, Gregory Szep, Andrea Trioni, Elena Redchenko,
    Martin Zemlicka, and Johannes M Fink. “Geometric Superinductance Qubits: Controlling
    Phase Delocalization across a Single Josephson Junction.” <i>PRX Quantum</i>.
    American Physical Society, 2021. <a href="https://doi.org/10.1103/PRXQuantum.2.040341">https://doi.org/10.1103/PRXQuantum.2.040341</a>.'
  ieee: 'M. Peruzzo <i>et al.</i>, “Geometric superinductance qubits: Controlling
    phase delocalization across a single Josephson junction,” <i>PRX Quantum</i>,
    vol. 2, no. 4. American Physical Society, p. 040341, 2021.'
  ista: 'Peruzzo M, Hassani F, Szep G, Trioni A, Redchenko E, Zemlicka M, Fink JM.
    2021. Geometric superinductance qubits: Controlling phase delocalization across
    a single Josephson junction. PRX Quantum. 2(4), 040341.'
  mla: 'Peruzzo, Matilda, et al. “Geometric Superinductance Qubits: Controlling Phase
    Delocalization across a Single Josephson Junction.” <i>PRX Quantum</i>, vol. 2,
    no. 4, American Physical Society, 2021, p. 040341, doi:<a href="https://doi.org/10.1103/PRXQuantum.2.040341">10.1103/PRXQuantum.2.040341</a>.'
  short: M. Peruzzo, F. Hassani, G. Szep, A. Trioni, E. Redchenko, M. Zemlicka, J.M.
    Fink, PRX Quantum 2 (2021) 040341.
date_created: 2021-08-17T08:14:18Z
date_published: 2021-11-24T00:00:00Z
date_updated: 2023-09-07T13:31:22Z
day: '24'
ddc:
- '530'
department:
- _id: JoFi
- _id: NanoFab
- _id: M-Shop
doi: 10.1103/PRXQuantum.2.040341
ec_funded: 1
external_id:
  arxiv:
  - '2106.05882'
  isi:
  - '000723015100001'
file:
- access_level: open_access
  checksum: 36eb41ea43d8ca22b0efab12419e4eb2
  content_type: application/pdf
  creator: cchlebak
  date_created: 2022-01-18T11:29:33Z
  date_updated: 2022-01-18T11:29:33Z
  file_id: '10641'
  file_name: 2021_PRXQuantum_Peruzzo.pdf
  file_size: 4247422
  relation: main_file
  success: 1
file_date_updated: 2022-01-18T11:29:33Z
has_accepted_license: '1'
intvolume: '         2'
isi: 1
issue: '4'
keyword:
- quantum physics
- mesoscale and nanoscale physics
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: '040341'
project:
- _id: 26927A52-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: F07105
  name: Integrating superconducting quantum circuits
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 2622978C-B435-11E9-9278-68D0E5697425
  name: Hybrid Semiconductor - Superconductor Quantum Devices
publication: PRX Quantum
publication_identifier:
  eissn:
  - 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '13057'
    relation: research_data
    status: public
  - id: '9920'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: 'Geometric superinductance qubits: Controlling phase delocalization across
  a single Josephson junction'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2
year: '2021'
...
---
_id: '9933'
abstract:
- lang: eng
  text: "In this paper, we study the power and limitations of component-stable algorithms
    in the low-space model of Massively Parallel Computation (MPC). Recently Ghaffari,
    Kuhn and Uitto (FOCS 2019) introduced the class of component-stable low-space
    MPC algorithms, which are, informally, defined as algorithms for which the outputs
    reported by the nodes in different connected components are required to be independent.
    This very natural notion was introduced to capture most (if not all) of the known
    efficient MPC algorithms to date, and it was the first general class of MPC algorithms
    for which one can show non-trivial conditional lower bounds. In this paper we
    enhance the framework of component-stable algorithms and investigate its effect
    on the complexity of randomized and deterministic low-space MPC. Our key contributions
    include: 1) We revise and formalize the lifting approach of Ghaffari, Kuhn and
    Uitto. This requires a very delicate amendment of the notion of component stability,
    which allows us to fill in gaps in the earlier arguments. 2) We also extend the
    framework to obtain conditional lower bounds for deterministic algorithms and
    fine-grained lower bounds that depend on the maximum degree Δ. 3) We demonstrate
    a collection of natural graph problems for which non-component-stable algorithms
    break the conditional lower bound obtained for component-stable algorithms. This
    implies that, for both deterministic and randomized algorithms, component-stable
    algorithms are conditionally weaker than the non-component-stable ones.\r\n\r\nAltogether
    our results imply that component-stability might limit the computational power
    of the low-space MPC model, paving the way for improved upper bounds that escape
    the conditional lower bound setting of Ghaffari, Kuhn, and Uitto."
acknowledgement: This work is partially supported by a Weizmann-UK Making Connections
  Grant, the Centre for Discrete Mathematics and its Applications (DIMAP), IBM Faculty
  Award, EPSRC award EP/V01305X/1, European Research Council (ERC) Grant No. 949083,
  the Minerva foundation with funding from the Federal German Ministry for Education
  and Research No. 713238, and the European Union’s Horizon 2020 programme under the
  Marie Skłodowska-Curie grant agreement No 754411.
article_processing_charge: No
arxiv: 1
author:
- first_name: Artur
  full_name: Czumaj, Artur
  last_name: Czumaj
- first_name: Peter
  full_name: Davies, Peter
  id: 11396234-BB50-11E9-B24C-90FCE5697425
  last_name: Davies
  orcid: 0000-0002-5646-9524
- first_name: Merav
  full_name: Parter, Merav
  last_name: Parter
citation:
  ama: 'Czumaj A, Davies P, Parter M. Component stability in low-space massively parallel
    computation. In: <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed
    Computing</i>. Association for Computing Machinery; 2021:481–491. doi:<a href="https://doi.org/10.1145/3465084.3467903">10.1145/3465084.3467903</a>'
  apa: 'Czumaj, A., Davies, P., &#38; Parter, M. (2021). Component stability in low-space
    massively parallel computation. In <i>Proceedings of the 2021 ACM Symposium on
    Principles of Distributed Computing</i> (pp. 481–491). Virtual, Italy: Association
    for Computing Machinery. <a href="https://doi.org/10.1145/3465084.3467903">https://doi.org/10.1145/3465084.3467903</a>'
  chicago: Czumaj, Artur, Peter Davies, and Merav Parter. “Component Stability in
    Low-Space Massively Parallel Computation.” In <i>Proceedings of the 2021 ACM Symposium
    on Principles of Distributed Computing</i>, 481–491. Association for Computing
    Machinery, 2021. <a href="https://doi.org/10.1145/3465084.3467903">https://doi.org/10.1145/3465084.3467903</a>.
  ieee: A. Czumaj, P. Davies, and M. Parter, “Component stability in low-space massively
    parallel computation,” in <i>Proceedings of the 2021 ACM Symposium on Principles
    of Distributed Computing</i>, Virtual, Italy, 2021, pp. 481–491.
  ista: 'Czumaj A, Davies P, Parter M. 2021. Component stability in low-space massively
    parallel computation. Proceedings of the 2021 ACM Symposium on Principles of Distributed
    Computing. PODC: Principles of Distributed Computing, 481–491.'
  mla: Czumaj, Artur, et al. “Component Stability in Low-Space Massively Parallel
    Computation.” <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed
    Computing</i>, Association for Computing Machinery, 2021, pp. 481–491, doi:<a
    href="https://doi.org/10.1145/3465084.3467903">10.1145/3465084.3467903</a>.
  short: A. Czumaj, P. Davies, M. Parter, in:, Proceedings of the 2021 ACM Symposium
    on Principles of Distributed Computing, Association for Computing Machinery, 2021,
    pp. 481–491.
conference:
  end_date: 2021-07-30
  location: Virtual, Italy
  name: 'PODC: Principles of Distributed Computing'
  start_date: 2021-07-26
date_created: 2021-08-17T18:11:16Z
date_published: 2021-07-21T00:00:00Z
date_updated: 2023-08-17T07:11:32Z
day: '21'
department:
- _id: DaAl
doi: 10.1145/3465084.3467903
ec_funded: 1
external_id:
  arxiv:
  - '2106.01880'
  isi:
  - '000744439800049'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2106.01880
month: '07'
oa: 1
oa_version: Submitted Version
page: 481–491
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing
publication_identifier:
  isbn:
  - '9781450385480'
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
status: public
title: Component stability in low-space massively parallel computation
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2021'
...
---
_id: '9935'
abstract:
- lang: eng
  text: "We present a deterministic O(log log log n)-round low-space Massively Parallel
    Computation (MPC) algorithm for the classical problem of (Δ+1)-coloring on n-vertex
    graphs. In this model, every machine has sublinear local space of size n^φ for
    any arbitrary constant φ \\in (0,1). Our algorithm works under the relaxed setting
    where each machine is allowed to perform exponential local computations, while
    respecting the n^φ space and bandwidth limitations.\r\n\r\nOur key technical contribution
    is a novel derandomization of the ingenious (Δ+1)-coloring local algorithm by
    Chang-Li-Pettie (STOC 2018, SIAM J. Comput. 2020). The Chang-Li-Pettie algorithm
    runs in T_local =poly(loglog n) rounds, which sets the state-of-the-art randomized
    round complexity for the problem in the local model. Our derandomization employs
    a combination of tools, notably pseudorandom generators (PRG) and bounded-independence
    hash functions.\r\n\r\nThe achieved round complexity of O(logloglog n) rounds
    matches the bound of log(T_local ), which currently serves an upper bound barrier
    for all known randomized algorithms for locally-checkable problems in this model.
    Furthermore, no deterministic sublogarithmic low-space MPC algorithms for the
    (Δ+1)-coloring problem have been known before."
acknowledgement: This work is partially supported by a Weizmann-UK Making Connections
  Grant, the Centre for Discrete Mathematics and its Applications (DIMAP), IBM Faculty
  Award, EPSRC award EP/V01305X/1, European Research Council (ERC) Grant No. 949083,
  the Minerva foundation with funding from the Federal German Ministry for Education
  and Research No. 713238, and the European Union’s Horizon 2020 programme under the
  Marie Skłodowska-Curie grant agreement No 754411.
article_processing_charge: No
author:
- first_name: Artur
  full_name: Czumaj, Artur
  last_name: Czumaj
- first_name: Peter
  full_name: Davies, Peter
  id: 11396234-BB50-11E9-B24C-90FCE5697425
  last_name: Davies
  orcid: 0000-0002-5646-9524
- first_name: Merav
  full_name: Parter, Merav
  last_name: Parter
citation:
  ama: 'Czumaj A, Davies P, Parter M. Improved deterministic (Δ+1) coloring in low-space
    MPC. In: <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed
    Computing</i>. Association for Computing Machinery; 2021:469–479. doi:<a href="https://doi.org/10.1145/3465084.3467937">10.1145/3465084.3467937</a>'
  apa: 'Czumaj, A., Davies, P., &#38; Parter, M. (2021). Improved deterministic (Δ+1)
    coloring in low-space MPC. In <i>Proceedings of the 2021 ACM Symposium on Principles
    of Distributed Computing</i> (pp. 469–479). Virtual, Italy: Association for Computing
    Machinery. <a href="https://doi.org/10.1145/3465084.3467937">https://doi.org/10.1145/3465084.3467937</a>'
  chicago: Czumaj, Artur, Peter Davies, and Merav Parter. “Improved Deterministic
    (Δ+1) Coloring in Low-Space MPC.” In <i>Proceedings of the 2021 ACM Symposium
    on Principles of Distributed Computing</i>, 469–479. Association for Computing
    Machinery, 2021. <a href="https://doi.org/10.1145/3465084.3467937">https://doi.org/10.1145/3465084.3467937</a>.
  ieee: A. Czumaj, P. Davies, and M. Parter, “Improved deterministic (Δ+1) coloring
    in low-space MPC,” in <i>Proceedings of the 2021 ACM Symposium on Principles of
    Distributed Computing</i>, Virtual, Italy, 2021, pp. 469–479.
  ista: 'Czumaj A, Davies P, Parter M. 2021. Improved deterministic (Δ+1) coloring
    in low-space MPC. Proceedings of the 2021 ACM Symposium on Principles of Distributed
    Computing. PODC: Symposium on Principles of Distributed Computing, 469–479.'
  mla: Czumaj, Artur, et al. “Improved Deterministic (Δ+1) Coloring in Low-Space MPC.”
    <i>Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing</i>,
    Association for Computing Machinery, 2021, pp. 469–479, doi:<a href="https://doi.org/10.1145/3465084.3467937">10.1145/3465084.3467937</a>.
  short: A. Czumaj, P. Davies, M. Parter, in:, Proceedings of the 2021 ACM Symposium
    on Principles of Distributed Computing, Association for Computing Machinery, 2021,
    pp. 469–479.
conference:
  end_date: 2021-07-30
  location: Virtual, Italy
  name: 'PODC: Symposium on Principles of Distributed Computing'
  start_date: 2021-07-26
date_created: 2021-08-17T18:14:15Z
date_published: 2021-07-21T00:00:00Z
date_updated: 2023-08-17T07:11:03Z
day: '21'
department:
- _id: DaAl
doi: 10.1145/3465084.3467937
ec_funded: 1
external_id:
  isi:
  - '000744439800048'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://wrap.warwick.ac.uk/153753
month: '07'
oa: 1
oa_version: Submitted Version
page: 469–479
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the 2021 ACM Symposium on Principles of Distributed Computing
publication_identifier:
  isbn:
  - 978-1-4503-8548-0
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
status: public
title: Improved deterministic (Δ+1) coloring in low-space MPC
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2021'
...
---
_id: '9946'
abstract:
- lang: eng
  text: We argue that the time is ripe to investigate differential monitoring, in
    which the specification of a program's behavior is implicitly given by a second
    program implementing the same informal specification. Similar ideas have been
    proposed before, and are currently implemented in restricted form for testing
    and specialized run-time analyses, aspects of which we combine. We discuss the
    challenges of implementing differential monitoring as a general-purpose, black-box
    run-time monitoring framework, and present promising results of a preliminary
    implementation, showing low monitoring overheads for diverse programs.
acknowledgement: The authors would like to thank Borzoo Bonakdarpour, Derek Dreyer,
  Adrian Francalanza, Owolabi Legunsen, Matthew Milano, Manuel Rigger, Cesar Sanchez,
  and the members of the IST Verification Seminar for their helpful comments and insights
  on various stages of this work, as well as the reviewers of RV’21 for their helpful
  suggestions on the actual paper.
alternative_title:
- IST Austria Technical Report
article_processing_charge: No
author:
- first_name: Fabian
  full_name: Mühlböck, Fabian
  id: 6395C5F6-89DF-11E9-9C97-6BDFE5697425
  last_name: Mühlböck
  orcid: 0000-0003-1548-0177
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
citation:
  ama: Mühlböck F, Henzinger TA. <i>Differential Monitoring</i>. IST Austria; 2021.
    doi:<a href="https://doi.org/10.15479/AT:ISTA:9946">10.15479/AT:ISTA:9946</a>
  apa: Mühlböck, F., &#38; Henzinger, T. A. (2021). <i>Differential monitoring</i>.
    IST Austria. <a href="https://doi.org/10.15479/AT:ISTA:9946">https://doi.org/10.15479/AT:ISTA:9946</a>
  chicago: Mühlböck, Fabian, and Thomas A Henzinger. <i>Differential Monitoring</i>.
    IST Austria, 2021. <a href="https://doi.org/10.15479/AT:ISTA:9946">https://doi.org/10.15479/AT:ISTA:9946</a>.
  ieee: F. Mühlböck and T. A. Henzinger, <i>Differential monitoring</i>. IST Austria,
    2021.
  ista: Mühlböck F, Henzinger TA. 2021. Differential monitoring, IST Austria, 17p.
  mla: Mühlböck, Fabian, and Thomas A. Henzinger. <i>Differential Monitoring</i>.
    IST Austria, 2021, doi:<a href="https://doi.org/10.15479/AT:ISTA:9946">10.15479/AT:ISTA:9946</a>.
  short: F. Mühlböck, T.A. Henzinger, Differential Monitoring, IST Austria, 2021.
date_created: 2021-08-20T20:00:37Z
date_published: 2021-09-01T00:00:00Z
date_updated: 2023-08-14T07:20:29Z
day: '01'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.15479/AT:ISTA:9946
file:
- access_level: open_access
  checksum: 0f9aafd59444cb6bdca6925d163ab946
  content_type: application/pdf
  creator: fmuehlbo
  date_created: 2021-08-20T19:59:44Z
  date_updated: 2021-09-03T12:34:28Z
  file_id: '9948'
  file_name: differentialmonitoring-techreport.pdf
  file_size: '320453'
  relation: main_file
file_date_updated: 2021-09-03T12:34:28Z
has_accepted_license: '1'
keyword:
- run-time verification
- software engineering
- implicit specification
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '17'
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
related_material:
  record:
  - id: '9281'
    relation: other
    status: public
  - id: '10108'
    relation: shorter_version
    status: public
status: public
title: Differential monitoring
type: technical_report
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2021'
...
---
_id: '9949'
article_processing_charge: No
author:
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Vicoso B. Data from Hyulmans et al 2021, “Transitions to asexuality and evolution
    of gene expression in Artemia brine shrimp.” 2021. doi:<a href="https://doi.org/10.15479/AT:ISTA:9949">10.15479/AT:ISTA:9949</a>
  apa: Vicoso, B. (2021). Data from Hyulmans et al 2021, “Transitions to asexuality
    and evolution of gene expression in Artemia brine shrimp.” Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:9949">https://doi.org/10.15479/AT:ISTA:9949</a>
  chicago: Vicoso, Beatriz. “Data from Hyulmans et Al 2021, ‘Transitions to Asexuality
    and Evolution of Gene Expression in Artemia Brine Shrimp.’” Institute of Science
    and Technology Austria, 2021. <a href="https://doi.org/10.15479/AT:ISTA:9949">https://doi.org/10.15479/AT:ISTA:9949</a>.
  ieee: B. Vicoso, “Data from Hyulmans et al 2021, ‘Transitions to asexuality and
    evolution of gene expression in Artemia brine shrimp.’” Institute of Science and
    Technology Austria, 2021.
  ista: Vicoso B. 2021. Data from Hyulmans et al 2021, ‘Transitions to asexuality
    and evolution of gene expression in Artemia brine shrimp’, Institute of Science
    and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:9949">10.15479/AT:ISTA:9949</a>.
  mla: Vicoso, Beatriz. <i>Data from Hyulmans et Al 2021, “Transitions to Asexuality
    and Evolution of Gene Expression in Artemia Brine Shrimp.”</i> Institute of Science
    and Technology Austria, 2021, doi:<a href="https://doi.org/10.15479/AT:ISTA:9949">10.15479/AT:ISTA:9949</a>.
  short: B. Vicoso, (2021).
date_created: 2021-08-21T13:44:22Z
date_published: 2021-08-24T00:00:00Z
date_updated: 2024-02-21T12:40:30Z
day: '24'
department:
- _id: BeVi
doi: 10.15479/AT:ISTA:9949
file:
- access_level: open_access
  checksum: 90461837eed66beac6fa302993cf0ca9
  content_type: application/zip
  creator: bvicoso
  date_created: 2021-08-21T13:43:59Z
  date_updated: 2021-08-21T13:43:59Z
  file_id: '9950'
  file_name: Data.zip
  file_size: 139188306
  relation: main_file
  success: 1
file_date_updated: 2021-08-21T13:43:59Z
has_accepted_license: '1'
month: '08'
oa: 1
oa_version: None
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '10166'
    relation: used_in_publication
    status: public
status: public
title: Data from Hyulmans et al 2021, "Transitions to asexuality and evolution of
  gene expression in Artemia brine shrimp"
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '9952'
abstract:
- lang: eng
  text: Proper control of division orientation and symmetry, largely determined by
    spindle positioning, is essential to development and homeostasis. Spindle positioning
    has been extensively studied in cells dividing in two-dimensional (2D) environments
    and in epithelial tissues, where proteins such as NuMA (also known as NUMA1) orient
    division along the interphase long axis of the cell. However, little is known
    about how cells control spindle positioning in three-dimensional (3D) environments,
    such as early mammalian embryos and a variety of adult tissues. Here, we use mouse
    embryonic stem cells (ESCs), which grow in 3D colonies, as a model to investigate
    division in 3D. We observe that, at the periphery of 3D colonies, ESCs display
    high spindle mobility and divide asymmetrically. Our data suggest that enhanced
    spindle movements are due to unequal distribution of the cell–cell junction protein
    E-cadherin between future daughter cells. Interestingly, when cells progress towards
    differentiation, division becomes more symmetric, with more elongated shapes in
    metaphase and enhanced cortical NuMA recruitment in anaphase. Altogether, this
    study suggests that in 3D contexts, the geometry of the cell and its contacts
    with neighbors control division orientation and symmetry.
acknowledgement: We would like to thank the entire Paluch and Baum laboratories at
  the MRC-LMCB and the Chalut lab at the Cambridge SCI for discussions and feedback
  throughout the project, and the MRC-LMCB microscopy platform, in particular Andrew
  Vaughan, for technical support.
article_number: jcs255018
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Agathe
  full_name: Chaigne, Agathe
  last_name: Chaigne
- first_name: Matthew B.
  full_name: Smith, Matthew B.
  last_name: Smith
- first_name: R. L.
  full_name: Cavestany, R. L.
  last_name: Cavestany
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Kevin J.
  full_name: Chalut, Kevin J.
  last_name: Chalut
- first_name: Ewa K.
  full_name: Paluch, Ewa K.
  last_name: Paluch
citation:
  ama: Chaigne A, Smith MB, Cavestany RL, Hannezo EB, Chalut KJ, Paluch EK. Three-dimensional
    geometry controls division symmetry in stem cell colonies. <i>Journal of Cell
    Science</i>. 2021;134(14). doi:<a href="https://doi.org/10.1242/jcs.255018">10.1242/jcs.255018</a>
  apa: Chaigne, A., Smith, M. B., Cavestany, R. L., Hannezo, E. B., Chalut, K. J.,
    &#38; Paluch, E. K. (2021). Three-dimensional geometry controls division symmetry
    in stem cell colonies. <i>Journal of Cell Science</i>. The Company of Biologists.
    <a href="https://doi.org/10.1242/jcs.255018">https://doi.org/10.1242/jcs.255018</a>
  chicago: Chaigne, Agathe, Matthew B. Smith, R. L. Cavestany, Edouard B Hannezo,
    Kevin J. Chalut, and Ewa K. Paluch. “Three-Dimensional Geometry Controls Division
    Symmetry in Stem Cell Colonies.” <i>Journal of Cell Science</i>. The Company of
    Biologists, 2021. <a href="https://doi.org/10.1242/jcs.255018">https://doi.org/10.1242/jcs.255018</a>.
  ieee: A. Chaigne, M. B. Smith, R. L. Cavestany, E. B. Hannezo, K. J. Chalut, and
    E. K. Paluch, “Three-dimensional geometry controls division symmetry in stem cell
    colonies,” <i>Journal of Cell Science</i>, vol. 134, no. 14. The Company of Biologists,
    2021.
  ista: Chaigne A, Smith MB, Cavestany RL, Hannezo EB, Chalut KJ, Paluch EK. 2021.
    Three-dimensional geometry controls division symmetry in stem cell colonies. Journal
    of Cell Science. 134(14), jcs255018.
  mla: Chaigne, Agathe, et al. “Three-Dimensional Geometry Controls Division Symmetry
    in Stem Cell Colonies.” <i>Journal of Cell Science</i>, vol. 134, no. 14, jcs255018,
    The Company of Biologists, 2021, doi:<a href="https://doi.org/10.1242/jcs.255018">10.1242/jcs.255018</a>.
  short: A. Chaigne, M.B. Smith, R.L. Cavestany, E.B. Hannezo, K.J. Chalut, E.K. Paluch,
    Journal of Cell Science 134 (2021).
date_created: 2021-08-22T22:01:20Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2023-08-11T10:55:36Z
day: '01'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1242/jcs.255018
external_id:
  isi:
  - '000681395800008'
file:
- access_level: open_access
  checksum: f086f9d7cb63b2474c01921cb060c513
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-23T07:32:20Z
  date_updated: 2021-08-23T07:32:20Z
  file_id: '9954'
  file_name: 2021_JournalOfCellScience_Chaigne.pdf
  file_size: 8651724
  relation: main_file
  success: 1
file_date_updated: 2021-08-23T07:32:20Z
has_accepted_license: '1'
intvolume: '       134'
isi: 1
issue: '14'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Journal of Cell Science
publication_identifier:
  eissn:
  - '14779137'
  issn:
  - '00219533'
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Three-dimensional geometry controls division symmetry in stem cell colonies
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 134
year: '2021'
...
---
_id: '9953'
abstract:
- lang: eng
  text: Chronic psychological stress is one of the most important triggers and environmental
    risk factors for neuropsychiatric disorders. Chronic stress can influence all
    organs via the secretion of stress hormones, including glucocorticoids by the
    adrenal glands, which coordinate the stress response across the body. In the brain,
    glucocorticoid receptors (GR) are expressed by various cell types including microglia,
    which are its resident immune cells regulating stress-induced inflammatory processes.
    To study the roles of microglial GR under normal homeostatic conditions and following
    chronic stress, we generated a mouse model in which the GR gene is depleted in
    microglia specifically at adulthood to prevent developmental confounds. We first
    confirmed that microglia were depleted in GR in our model in males and females
    among the cingulate cortex and the hippocampus, both stress-sensitive brain regions.
    Then, cohorts of microglial-GR depleted and wild-type (WT) adult female mice were
    housed for 3 weeks in a standard or stressful condition, using a chronic unpredictable
    mild stress (CUMS) paradigm. CUMS induced stress-related behavior in both microglial-GR
    depleted and WT animals as demonstrated by a decrease of both saccharine preference
    and progressive ratio breakpoint. Nevertheless, the hippocampal microglial and
    neural mechanisms underlying the adaptation to stress occurred differently between
    the two genotypes. Upon CUMS exposure, microglial morphology was altered in the
    WT controls, without any apparent effect in microglial-GR depleted mice. Furthermore,
    in the standard environment condition, GR depleted-microglia showed increased
    expression of pro-inflammatory genes, and genes involved in microglial homeostatic
    functions (such as Trem2, Cx3cr1 and Mertk). On the contrary, in CUMS condition,
    GR depleted-microglia showed reduced expression levels of pro-inflammatory genes
    and increased neuroprotective as well as anti-inflammatory genes compared to WT-microglia.
    Moreover, in microglial-GR depleted mice, but not in WT mice, CUMS led to a significant
    reduction of CA1 long-term potentiation and paired-pulse ratio. Lastly, differences
    in adult hippocampal neurogenesis were observed between the genotypes during normal
    homeostatic conditions, with microglial-GR deficiency increasing the formation
    of newborn neurons in the dentate gyrus subgranular zone independently from stress
    exposure. Together, these findings indicate that, although the deletion of microglial
    GR did not prevent the animal’s ability to respond to stress, it contributed to
    modulating hippocampal functions in both standard and stressful conditions, notably
    by shaping the microglial response to chronic stress.
acknowledgement: We acknowledge that Université Laval stands on the traditional and
  unceded land of the Huron-Wendat peoples; and that the University of Victoria exists
  on the territory of the Lekwungen peoples and that the Songhees, Esquimalt and WSÁNEÆ
  peoples have relationships to this land. We thank Emmanuel Planel for the access
  to the epifluorescence microscope and Julie-Christine Lévesque at the Bioimaging
  Platform of CRCHU de Québec-Université Laval for technical assistance. We also thank
  the Centre for Advanced Materials and Related Technology for the access to the confocal
  microscope with Airyscan. K.P. was supported by a doctoral scholarship from Fonds
  de Recherche du Québec – Santé (FRQS), an excellence award from Fondation du CHU
  de Québec, as well as from Centre Thématique de Recherche en Neurosciences and from
  Fondation Famille-Choquette. K.B. was supported by excellence scholarships from
  Université Laval and Fondation du CHU de Québec. S.G. is supported by FIRC-AIRC
  fellowship for Italy 22329/2018 and by Pilot ARISLA NKINALS 2019. C.W.H. and J.C.S.
  were supported by postdoctoral fellowships from FRQS. This study was funded by a
  Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery grant
  (RGPIN-2014-05308) awarded to M.E.T., by ERANET neuron 2017 MicroSynDep to M.E.T.
  and I.B., and by the Italian Ministry of Health, grant RF-2018-12367249 to I.B,
  by PRIN 2017, AIRC 2019 and Ministero della Salute RF2018 to C.L. M.E.T. is a Tier
  II Canada Research Chair in Neurobiology of Aging and Cognition.
article_processing_charge: No
article_type: original
author:
- first_name: Katherine
  full_name: Picard, Katherine
  last_name: Picard
- first_name: Kanchan
  full_name: Bisht, Kanchan
  last_name: Bisht
- first_name: Silvia
  full_name: Poggini, Silvia
  last_name: Poggini
- first_name: Stefano
  full_name: Garofalo, Stefano
  last_name: Garofalo
- first_name: Maria Teresa
  full_name: Golia, Maria Teresa
  last_name: Golia
- first_name: Bernadette
  full_name: Basilico, Bernadette
  id: 36035796-5ACA-11E9-A75E-7AF2E5697425
  last_name: Basilico
  orcid: 0000-0003-1843-3173
- first_name: Fatima
  full_name: Abdallah, Fatima
  last_name: Abdallah
- first_name: Naomi
  full_name: Ciano Albanese, Naomi
  last_name: Ciano Albanese
- first_name: Irmgard
  full_name: Amrein, Irmgard
  last_name: Amrein
- first_name: Nathalie
  full_name: Vernoux, Nathalie
  last_name: Vernoux
- first_name: Kaushik
  full_name: Sharma, Kaushik
  last_name: Sharma
- first_name: Chin Wai
  full_name: Hui, Chin Wai
  last_name: Hui
- first_name: Julie
  full_name: C. Savage, Julie
  last_name: C. Savage
- first_name: Cristina
  full_name: Limatola, Cristina
  last_name: Limatola
- first_name: Davide
  full_name: Ragozzino, Davide
  last_name: Ragozzino
- first_name: Laura
  full_name: Maggi, Laura
  last_name: Maggi
- first_name: Igor
  full_name: Branchi, Igor
  last_name: Branchi
- first_name: Marie Ève
  full_name: Tremblay, Marie Ève
  last_name: Tremblay
citation:
  ama: Picard K, Bisht K, Poggini S, et al. Microglial-glucocorticoid receptor depletion
    alters the response of hippocampal microglia and neurons in a chronic unpredictable
    mild stress paradigm in female mice. <i>Brain, Behavior, and Immunity</i>. 2021;97:423-439.
    doi:<a href="https://doi.org/10.1016/j.bbi.2021.07.022">10.1016/j.bbi.2021.07.022</a>
  apa: Picard, K., Bisht, K., Poggini, S., Garofalo, S., Golia, M. T., Basilico, B.,
    … Tremblay, M. È. (2021). Microglial-glucocorticoid receptor depletion alters
    the response of hippocampal microglia and neurons in a chronic unpredictable mild
    stress paradigm in female mice. <i>Brain, Behavior, and Immunity</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.bbi.2021.07.022">https://doi.org/10.1016/j.bbi.2021.07.022</a>
  chicago: Picard, Katherine, Kanchan Bisht, Silvia Poggini, Stefano Garofalo, Maria
    Teresa Golia, Bernadette Basilico, Fatima Abdallah, et al. “Microglial-Glucocorticoid
    Receptor Depletion Alters the Response of Hippocampal Microglia and Neurons in
    a Chronic Unpredictable Mild Stress Paradigm in Female Mice.” <i>Brain, Behavior,
    and Immunity</i>. Elsevier, 2021. <a href="https://doi.org/10.1016/j.bbi.2021.07.022">https://doi.org/10.1016/j.bbi.2021.07.022</a>.
  ieee: K. Picard <i>et al.</i>, “Microglial-glucocorticoid receptor depletion alters
    the response of hippocampal microglia and neurons in a chronic unpredictable mild
    stress paradigm in female mice,” <i>Brain, Behavior, and Immunity</i>, vol. 97.
    Elsevier, pp. 423–439, 2021.
  ista: Picard K, Bisht K, Poggini S, Garofalo S, Golia MT, Basilico B, Abdallah F,
    Ciano Albanese N, Amrein I, Vernoux N, Sharma K, Hui CW, C. Savage J, Limatola
    C, Ragozzino D, Maggi L, Branchi I, Tremblay MÈ. 2021. Microglial-glucocorticoid
    receptor depletion alters the response of hippocampal microglia and neurons in
    a chronic unpredictable mild stress paradigm in female mice. Brain, Behavior,
    and Immunity. 97, 423–439.
  mla: Picard, Katherine, et al. “Microglial-Glucocorticoid Receptor Depletion Alters
    the Response of Hippocampal Microglia and Neurons in a Chronic Unpredictable Mild
    Stress Paradigm in Female Mice.” <i>Brain, Behavior, and Immunity</i>, vol. 97,
    Elsevier, 2021, pp. 423–39, doi:<a href="https://doi.org/10.1016/j.bbi.2021.07.022">10.1016/j.bbi.2021.07.022</a>.
  short: K. Picard, K. Bisht, S. Poggini, S. Garofalo, M.T. Golia, B. Basilico, F.
    Abdallah, N. Ciano Albanese, I. Amrein, N. Vernoux, K. Sharma, C.W. Hui, J. C.
    Savage, C. Limatola, D. Ragozzino, L. Maggi, I. Branchi, M.È. Tremblay, Brain,
    Behavior, and Immunity 97 (2021) 423–439.
date_created: 2021-08-22T22:01:21Z
date_published: 2021-10-01T00:00:00Z
date_updated: 2023-10-03T09:49:18Z
day: '01'
department:
- _id: GaNo
doi: 10.1016/j.bbi.2021.07.022
external_id:
  isi:
  - '000702878400007'
  pmid:
  - '34343616'
intvolume: '        97'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.zora.uzh.ch/id/eprint/208855/1/ZORA208855.pdf
month: '10'
oa: 1
oa_version: Submitted Version
page: 423-439
pmid: 1
publication: Brain, Behavior, and Immunity
publication_identifier:
  issn:
  - 0889-1591
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Microglial-glucocorticoid receptor depletion alters the response of hippocampal
  microglia and neurons in a chronic unpredictable mild stress paradigm in female
  mice
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 97
year: '2021'
...
---
_id: '9957'
abstract:
- lang: eng
  text: The reflectance field of a face describes the reflectance properties responsible
    for complex lighting effects including diffuse, specular, inter-reflection and
    self shadowing. Most existing methods for estimating the face reflectance from
    a monocular image assume faces to be diffuse with very few approaches adding a
    specular component. This still leaves out important perceptual aspects of reflectance
    as higher-order global illumination effects and self-shadowing are not modeled.
    We present a new neural representation for face reflectance where we can estimate
    all components of the reflectance responsible for the final appearance from a
    single monocular image. Instead of modeling each component of the reflectance
    separately using parametric models, our neural representation allows us to generate
    a basis set of faces in a geometric deformation-invariant space, parameterized
    by the input light direction, viewpoint and face geometry. We learn to reconstruct
    this reflectance field of a face just from a monocular image, which can be used
    to render the face from any viewpoint in any light condition. Our method is trained
    on a light-stage training dataset, which captures 300 people illuminated with
    150 light conditions from 8 viewpoints. We show that our method outperforms existing
    monocular reflectance reconstruction methods, in terms of photorealism due to
    better capturing of physical premitives, such as sub-surface scattering, specularities,
    self-shadows and other higher-order effects.
acknowledgement: "We thank Tarun Yenamandra and Duarte David for helping us with the
  comparisons. This work was supported by the\r\nERC Consolidator Grant 4DReply (770784).
  We also acknowledge support from InterDigital."
article_processing_charge: No
arxiv: 1
author:
- first_name: Mallikarjun
  full_name: B R, Mallikarjun
  last_name: B R
- first_name: Ayush
  full_name: Tewari, Ayush
  last_name: Tewari
- first_name: Tae-Hyun
  full_name: Oh, Tae-Hyun
  last_name: Oh
- first_name: Tim
  full_name: Weyrich, Tim
  last_name: Weyrich
- first_name: Bernd
  full_name: Bickel, Bernd
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
- first_name: Hans-Peter
  full_name: Seidel, Hans-Peter
  last_name: Seidel
- first_name: Hanspeter
  full_name: Pfister, Hanspeter
  last_name: Pfister
- first_name: Wojciech
  full_name: Matusik, Wojciech
  last_name: Matusik
- first_name: Mohamed
  full_name: Elgharib, Mohamed
  last_name: Elgharib
- first_name: Christian
  full_name: Theobalt, Christian
  last_name: Theobalt
citation:
  ama: 'B R M, Tewari A, Oh T-H, et al. Monocular reconstruction of neural face reflectance
    fields. In: <i>Proceedings of the IEEE Computer Society Conference on Computer
    Vision and Pattern Recognition</i>. IEEE; 2021:4791-4800. doi:<a href="https://doi.org/10.1109/CVPR46437.2021.00476">10.1109/CVPR46437.2021.00476</a>'
  apa: 'B R, M., Tewari, A., Oh, T.-H., Weyrich, T., Bickel, B., Seidel, H.-P., …
    Theobalt, C. (2021). Monocular reconstruction of neural face reflectance fields.
    In <i>Proceedings of the IEEE Computer Society Conference on Computer Vision and
    Pattern Recognition</i> (pp. 4791–4800). Nashville, TN, United States; Virtual:
    IEEE. <a href="https://doi.org/10.1109/CVPR46437.2021.00476">https://doi.org/10.1109/CVPR46437.2021.00476</a>'
  chicago: B R, Mallikarjun, Ayush Tewari, Tae-Hyun Oh, Tim Weyrich, Bernd Bickel,
    Hans-Peter Seidel, Hanspeter Pfister, Wojciech Matusik, Mohamed Elgharib, and
    Christian Theobalt. “Monocular Reconstruction of Neural Face Reflectance Fields.”
    In <i>Proceedings of the IEEE Computer Society Conference on Computer Vision and
    Pattern Recognition</i>, 4791–4800. IEEE, 2021. <a href="https://doi.org/10.1109/CVPR46437.2021.00476">https://doi.org/10.1109/CVPR46437.2021.00476</a>.
  ieee: M. B R <i>et al.</i>, “Monocular reconstruction of neural face reflectance
    fields,” in <i>Proceedings of the IEEE Computer Society Conference on Computer
    Vision and Pattern Recognition</i>, Nashville, TN, United States; Virtual, 2021,
    pp. 4791–4800.
  ista: 'B R M, Tewari A, Oh T-H, Weyrich T, Bickel B, Seidel H-P, Pfister H, Matusik
    W, Elgharib M, Theobalt C. 2021. Monocular reconstruction of neural face reflectance
    fields. Proceedings of the IEEE Computer Society Conference on Computer Vision
    and Pattern Recognition. CVPR: Conference on Computer Vision and Pattern Recognition,
    4791–4800.'
  mla: B R, Mallikarjun, et al. “Monocular Reconstruction of Neural Face Reflectance
    Fields.” <i>Proceedings of the IEEE Computer Society Conference on Computer Vision
    and Pattern Recognition</i>, IEEE, 2021, pp. 4791–800, doi:<a href="https://doi.org/10.1109/CVPR46437.2021.00476">10.1109/CVPR46437.2021.00476</a>.
  short: M. B R, A. Tewari, T.-H. Oh, T. Weyrich, B. Bickel, H.-P. Seidel, H. Pfister,
    W. Matusik, M. Elgharib, C. Theobalt, in:, Proceedings of the IEEE Computer Society
    Conference on Computer Vision and Pattern Recognition, IEEE, 2021, pp. 4791–4800.
conference:
  end_date: 2021-06-25
  location: Nashville, TN, United States; Virtual
  name: 'CVPR: Conference on Computer Vision and Pattern Recognition'
  start_date: 2021-06-20
date_created: 2021-08-24T06:03:00Z
date_published: 2021-09-01T00:00:00Z
date_updated: 2023-08-11T11:08:35Z
day: '01'
ddc:
- '000'
department:
- _id: BeBi
doi: 10.1109/CVPR46437.2021.00476
external_id:
  arxiv:
  - '2008.10247'
  isi:
  - '000739917304096'
file:
- access_level: open_access
  checksum: 961db0bde76dd87cf833930080bb9f38
  content_type: application/pdf
  creator: bbickel
  date_created: 2021-08-24T06:02:15Z
  date_updated: 2021-08-24T06:02:15Z
  file_id: '9958'
  file_name: R_Monocular_Reconstruction_of_Neural_Face_Reflectance_Fields_CVPR_2021_paper[1].pdf
  file_size: 4746649
  relation: main_file
file_date_updated: 2021-08-24T06:02:15Z
has_accepted_license: '1'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Preprint
page: 4791-4800
publication: Proceedings of the IEEE Computer Society Conference on Computer Vision
  and Pattern Recognition
publication_identifier:
  isbn:
  - 978-166544509-2
  issn:
  - 1063-6919
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Monocular reconstruction of neural face reflectance fields
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2021'
...
