[{"title":"Adaptive security of constrained PRFs","date_published":"2014-01-01T00:00:00Z","quality_controlled":0,"conference":{"name":"Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)"},"publisher":"Springer","main_file_link":[{"open_access":"1","url":"http://eprint.iacr.org/2014/416"}],"year":"2014","volume":8874,"date_created":"2018-12-11T11:54:45Z","intvolume":"      8874","page":"173 - 192","abstract":[{"lang":"eng","text":"Constrained pseudorandom functions have recently been introduced independently by Boneh and Waters (Asiacrypt’13), Kiayias et al. (CCS’13), and Boyle et al. (PKC’14). In a standard pseudorandom function (PRF) a key k is used to evaluate the PRF on all inputs in the domain. Constrained PRFs additionally offer the functionality to delegate “constrained” keys kS which allow to evaluate the PRF only on a subset S of the domain. The three above-mentioned papers all show that the classical GGM construction (J.ACM’86) of a PRF from a pseudorandom generator (PRG) directly yields a constrained PRF where one can compute constrained keys to evaluate the PRF on all inputs with a given prefix. This constrained PRF has already found many interesting applications. Unfortunately, the existing security proofs only show selective security (by a reduction to the security of the underlying PRG). To achieve full security, one has to use complexity leveraging, which loses an exponential factor 2N in security, where N is the input length. The first contribution of this paper is a new reduction that only loses a quasipolynomial factor qlog N, where q is the number of adversarial queries. For this we develop a new proof technique which constructs a distinguisher by interleaving simple guessing steps and hybrid arguments a small number of times. This approach might be of interest also in other contexts where currently the only technique to achieve full security is complexity leveraging. Our second contribution is concerned with another constrained PRF, due to Boneh and Waters, which allows for constrained keys for the more general class of bit-fixing functions. Their security proof also suffers from a 2N loss, which we show is inherent. We construct a meta-reduction which shows that any “simple” reduction of full security from a noninteractive hardness assumption must incur an exponential security loss."}],"doi":"10.1145/2591796.2591825","publist_id":"5167","status":"public","_id":"1927","acknowledgement":"We are grateful to Mihir Bellare for his feedback on earlier versions of this paper. We are indebted to Vanishree Rao for her generous assistance in preparing this proceedings version.","date_updated":"2021-01-12T06:54:08Z","publication_status":"published","day":"01","citation":{"ieee":"G. Fuchsbauer, M. Konstantinov, K. Z. Pietrzak, and V. Rao, “Adaptive security of constrained PRFs,” presented at the Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2014, vol. 8874, pp. 173–192.","ama":"Fuchsbauer G, Konstantinov M, Pietrzak KZ, Rao V. Adaptive security of constrained PRFs. In: Vol 8874. Springer; 2014:173-192. doi:<a href=\"https://doi.org/10.1145/2591796.2591825\">10.1145/2591796.2591825</a>","short":"G. Fuchsbauer, M. Konstantinov, K.Z. Pietrzak, V. Rao, in:, Springer, 2014, pp. 173–192.","chicago":"Fuchsbauer, Georg, Momchil Konstantinov, Krzysztof Z Pietrzak, and Vanishree Rao. “Adaptive Security of Constrained PRFs,” 8874:173–92. Springer, 2014. <a href=\"https://doi.org/10.1145/2591796.2591825\">https://doi.org/10.1145/2591796.2591825</a>.","ista":"Fuchsbauer G, Konstantinov M, Pietrzak KZ, Rao V. 2014. Adaptive security of constrained PRFs. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) vol. 8874, 173–192.","mla":"Fuchsbauer, Georg, et al. <i>Adaptive Security of Constrained PRFs</i>. Vol. 8874, Springer, 2014, pp. 173–92, doi:<a href=\"https://doi.org/10.1145/2591796.2591825\">10.1145/2591796.2591825</a>.","apa":"Fuchsbauer, G., Konstantinov, M., Pietrzak, K. Z., &#38; Rao, V. (2014). Adaptive security of constrained PRFs (Vol. 8874, pp. 173–192). Presented at the Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Springer. <a href=\"https://doi.org/10.1145/2591796.2591825\">https://doi.org/10.1145/2591796.2591825</a>"},"extern":1,"author":[{"last_name":"Fuchsbauer","full_name":"Georg Fuchsbauer","id":"46B4C3EE-F248-11E8-B48F-1D18A9856A87","first_name":"Georg"},{"full_name":"Konstantinov, Momchil","first_name":"Momchil","last_name":"Konstantinov"},{"last_name":"Pietrzak","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","full_name":"Krzysztof Pietrzak","first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654"},{"first_name":"Vanishree","full_name":"Rao, Vanishree","last_name":"Rao"}],"oa":1,"type":"conference","month":"01"},{"language":[{"iso":"eng"}],"intvolume":"         8","article_number":"57","publisher":"Frontiers Research Foundation","day":"28","acknowledgement":"Supported in part by EC MEXT project PLICON and the LOEWE-Program “Neuronal Coordination Research Focus Frankfurt” (NeFF). Jochen Triesch was supported by the Quandt foundation.","publication_status":"published","month":"05","doi":"10.3389/fncom.2014.00057","abstract":[{"lang":"eng","text":"A wealth of experimental evidence suggests that working memory circuits preferentially represent information that is behaviorally relevant. Still, we are missing a mechanistic account of how these representations come about. Here we provide a simple explanation for a range of experimental findings, in light of prefrontal circuits adapting to task constraints by reward-dependent learning. In particular, we model a neural network shaped by reward-modulated spike-timing dependent plasticity (r-STDP) and homeostatic plasticity (intrinsic excitability and synaptic scaling). We show that the experimentally-observed neural representations naturally emerge in an initially unstructured circuit as it learns to solve several working memory tasks. These results point to a critical, and previously unappreciated, role for reward-dependent learning in shaping prefrontal cortex activity."}],"publist_id":"5163","issue":"MAY","status":"public","volume":8,"publication":"Frontiers in Computational Neuroscience","main_file_link":[{"open_access":"1","url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035833/"}],"year":"2014","date_created":"2018-12-11T11:54:46Z","quality_controlled":"1","title":"Emergence of task-dependent representations in working memory circuits","date_published":"2014-05-28T00:00:00Z","author":[{"last_name":"Savin","id":"3933349E-F248-11E8-B48F-1D18A9856A87","first_name":"Cristina","full_name":"Savin, Cristina"},{"last_name":"Triesch","full_name":"Triesch, Jochen","first_name":"Jochen"}],"oa":1,"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","citation":{"chicago":"Savin, Cristina, and Jochen Triesch. “Emergence of Task-Dependent Representations in Working Memory Circuits.” <i>Frontiers in Computational Neuroscience</i>. Frontiers Research Foundation, 2014. <a href=\"https://doi.org/10.3389/fncom.2014.00057\">https://doi.org/10.3389/fncom.2014.00057</a>.","ama":"Savin C, Triesch J. Emergence of task-dependent representations in working memory circuits. <i>Frontiers in Computational Neuroscience</i>. 2014;8(MAY). doi:<a href=\"https://doi.org/10.3389/fncom.2014.00057\">10.3389/fncom.2014.00057</a>","short":"C. Savin, J. Triesch, Frontiers in Computational Neuroscience 8 (2014).","ieee":"C. Savin and J. Triesch, “Emergence of task-dependent representations in working memory circuits,” <i>Frontiers in Computational Neuroscience</i>, vol. 8, no. MAY. Frontiers Research Foundation, 2014.","mla":"Savin, Cristina, and Jochen Triesch. “Emergence of Task-Dependent Representations in Working Memory Circuits.” <i>Frontiers in Computational Neuroscience</i>, vol. 8, no. MAY, 57, Frontiers Research Foundation, 2014, doi:<a href=\"https://doi.org/10.3389/fncom.2014.00057\">10.3389/fncom.2014.00057</a>.","apa":"Savin, C., &#38; Triesch, J. (2014). Emergence of task-dependent representations in working memory circuits. <i>Frontiers in Computational Neuroscience</i>. Frontiers Research Foundation. <a href=\"https://doi.org/10.3389/fncom.2014.00057\">https://doi.org/10.3389/fncom.2014.00057</a>","ista":"Savin C, Triesch J. 2014. Emergence of task-dependent representations in working memory circuits. Frontiers in Computational Neuroscience. 8(MAY), 57."},"department":[{"_id":"GaTk"}],"date_updated":"2021-01-12T06:54:09Z","oa_version":"Submitted Version","type":"journal_article","scopus_import":1,"_id":"1931"},{"quality_controlled":"1","project":[{"_id":"25B07788-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"Limits to selection in biology and in evolutionary computation","grant_number":"250152"}],"title":"Cryptic genetic variation can make &quot;irreducible complexity&quot; a common mode of adaptation in sexual populations","date_published":"2014-12-01T00:00:00Z","date_created":"2018-12-11T11:54:47Z","publication":"Evolution","volume":68,"main_file_link":[{"url":"http://arxiv.org/abs/1310.6077","open_access":"1"}],"year":"2014","_id":"1932","scopus_import":1,"type":"journal_article","citation":{"ista":"Trotter M, Weissman D, Peterson G, Peck K, Masel J. 2014. Cryptic genetic variation can make &#38;quot;irreducible complexity&#38;quot; a common mode of adaptation in sexual populations. Evolution. 68(12), 3357–3367.","apa":"Trotter, M., Weissman, D., Peterson, G., Peck, K., &#38; Masel, J. (2014). Cryptic genetic variation can make &#38;quot;irreducible complexity&#38;quot; a common mode of adaptation in sexual populations. <i>Evolution</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/evo.12517\">https://doi.org/10.1111/evo.12517</a>","mla":"Trotter, Meredith, et al. “Cryptic Genetic Variation Can Make &#38;quot;Irreducible Complexity&#38;quot; a Common Mode of Adaptation in Sexual Populations.” <i>Evolution</i>, vol. 68, no. 12, Wiley-Blackwell, 2014, pp. 3357–67, doi:<a href=\"https://doi.org/10.1111/evo.12517\">10.1111/evo.12517</a>.","ieee":"M. Trotter, D. Weissman, G. Peterson, K. Peck, and J. Masel, “Cryptic genetic variation can make &#38;quot;irreducible complexity&#38;quot; a common mode of adaptation in sexual populations,” <i>Evolution</i>, vol. 68, no. 12. Wiley-Blackwell, pp. 3357–3367, 2014.","short":"M. Trotter, D. Weissman, G. Peterson, K. Peck, J. Masel, Evolution 68 (2014) 3357–3367.","ama":"Trotter M, Weissman D, Peterson G, Peck K, Masel J. Cryptic genetic variation can make &#38;quot;irreducible complexity&#38;quot; a common mode of adaptation in sexual populations. <i>Evolution</i>. 2014;68(12):3357-3367. doi:<a href=\"https://doi.org/10.1111/evo.12517\">10.1111/evo.12517</a>","chicago":"Trotter, Meredith, Daniel Weissman, Grant Peterson, Kayla Peck, and Joanna Masel. “Cryptic Genetic Variation Can Make &#38;quot;Irreducible Complexity&#38;quot; a Common Mode of Adaptation in Sexual Populations.” <i>Evolution</i>. Wiley-Blackwell, 2014. <a href=\"https://doi.org/10.1111/evo.12517\">https://doi.org/10.1111/evo.12517</a>."},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","oa":1,"author":[{"full_name":"Trotter, Meredith","first_name":"Meredith","last_name":"Trotter"},{"first_name":"Daniel","id":"2D0CE020-F248-11E8-B48F-1D18A9856A87","full_name":"Weissman, Daniel","last_name":"Weissman"},{"full_name":"Peterson, Grant","first_name":"Grant","last_name":"Peterson"},{"full_name":"Peck, Kayla","first_name":"Kayla","last_name":"Peck"},{"full_name":"Masel, Joanna","first_name":"Joanna","last_name":"Masel"}],"oa_version":"Submitted Version","date_updated":"2021-01-12T06:54:10Z","department":[{"_id":"NiBa"}],"publisher":"Wiley-Blackwell","page":"3357 - 3367","intvolume":"        68","language":[{"iso":"eng"}],"status":"public","abstract":[{"text":"The existence of complex (multiple-step) genetic adaptations that are &quot;irreducible&quot; (i.e., all partial combinations are less fit than the original genotype) is one of the longest standing problems in evolutionary biology. In standard genetics parlance, these adaptations require the crossing of a wide adaptive valley of deleterious intermediate stages. Here, we demonstrate, using a simple model, that evolution can cross wide valleys to produce &quot;irreducibly complex&quot; adaptations by making use of previously cryptic mutations. When revealed by an evolutionary capacitor, previously cryptic mutants have higher initial frequencies than do new mutations, bringing them closer to a valley-crossing saddle in allele frequency space. Moreover, simple combinatorics implies an enormous number of candidate combinations exist within available cryptic genetic variation. We model the dynamics of crossing of a wide adaptive valley after a capacitance event using both numerical simulations and analytical approximations. Although individual valley crossing events become less likely as valleys widen, by taking the combinatorics of genotype space into account, we see that revealing cryptic variation can cause the frequent evolution of complex adaptations.","lang":"eng"}],"publist_id":"5162","doi":"10.1111/evo.12517","issue":"12","month":"12","day":"01","ec_funded":1,"publication_status":"published","acknowledgement":"Funded by National Institutes of Health. Grant Numbers: R01GM076041, R01GM104040         \r\n\r\nSimons Foundation\r\n\r\n"},{"abstract":[{"lang":"eng","text":"We consider Ising models in d = 2 and d = 3 dimensions with nearest neighbor ferromagnetic and long-range antiferromagnetic interactions, the latter decaying as (distance)-p, p &gt; 2d, at large distances. If the strength J of the ferromagnetic interaction is larger than a critical value J c, then the ground state is homogeneous. It has been conjectured that when J is smaller than but close to J c, the ground state is periodic and striped, with stripes of constant width h = h(J), and h → ∞ as J → Jc -. (In d = 3 stripes mean slabs, not columns.) Here we rigorously prove that, if we normalize the energy in such a way that the energy of the homogeneous state is zero, then the ratio e 0(J)/e S(J) tends to 1 as J → Jc -, with e S(J) being the energy per site of the optimal periodic striped/slabbed state and e 0(J) the actual ground state energy per site of the system. Our proof comes with explicit bounds on the difference e 0(J)-e S(J) at small but positive J c-J, and also shows that in this parameter range the ground state is striped/slabbed in a certain sense: namely, if one looks at a randomly chosen window, of suitable size ℓ (very large compared to the optimal stripe size h(J)), one finds a striped/slabbed state with high probability."}],"publist_id":"5159","doi":"10.1007/s00220-014-1923-2","publication_identifier":{"issn":["0010-3616"],"eissn":["1432-0916"]},"status":"public","day":"01","publication_status":"published","acknowledgement":"2014 by the authors. This paper may be reproduced, in its entirety, for non-commercial purposes.\r\n\r\nThe research leading to these results has received funding from the European Research\r\nCouncil under the European Union’s Seventh Framework Programme ERC Starting Grant CoMBoS (Grant Agreement No. 239694; A.G. and R.S.), the U.S. National Science Foundation (Grant PHY 0965859; E.H.L.), the Simons Foundation (Grant # 230207; E.H.L) and the NSERC (R.S.). The work is part of a project started in collaboration with Joel Lebowitz, whom we thank for many useful discussions and for his constant encouragement.","month":"10","publisher":"Springer","arxiv":1,"language":[{"iso":"eng"}],"page":"333 - 350","article_type":"original","intvolume":"       331","scopus_import":"1","file_date_updated":"2022-05-24T08:30:40Z","external_id":{"arxiv":["1304.6344"]},"_id":"1935","author":[{"full_name":"Giuliani, Alessandro","first_name":"Alessandro","last_name":"Giuliani"},{"full_name":"Lieb, Élliott","first_name":"Élliott","last_name":"Lieb"},{"last_name":"Seiringer","full_name":"Seiringer, Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","orcid":"0000-0002-6781-0521"}],"oa":1,"has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Giuliani A, Lieb É, Seiringer R. 2014. Formation of stripes and slabs near the ferromagnetic transition. Communications in Mathematical Physics. 331, 333–350.","apa":"Giuliani, A., Lieb, É., &#38; Seiringer, R. (2014). Formation of stripes and slabs near the ferromagnetic transition. <i>Communications in Mathematical Physics</i>. Springer. <a href=\"https://doi.org/10.1007/s00220-014-1923-2\">https://doi.org/10.1007/s00220-014-1923-2</a>","mla":"Giuliani, Alessandro, et al. “Formation of Stripes and Slabs near the Ferromagnetic Transition.” <i>Communications in Mathematical Physics</i>, vol. 331, Springer, 2014, pp. 333–50, doi:<a href=\"https://doi.org/10.1007/s00220-014-1923-2\">10.1007/s00220-014-1923-2</a>.","ama":"Giuliani A, Lieb É, Seiringer R. Formation of stripes and slabs near the ferromagnetic transition. <i>Communications in Mathematical Physics</i>. 2014;331:333-350. doi:<a href=\"https://doi.org/10.1007/s00220-014-1923-2\">10.1007/s00220-014-1923-2</a>","short":"A. Giuliani, É. Lieb, R. Seiringer, Communications in Mathematical Physics 331 (2014) 333–350.","chicago":"Giuliani, Alessandro, Élliott Lieb, and Robert Seiringer. “Formation of Stripes and Slabs near the Ferromagnetic Transition.” <i>Communications in Mathematical Physics</i>. Springer, 2014. <a href=\"https://doi.org/10.1007/s00220-014-1923-2\">https://doi.org/10.1007/s00220-014-1923-2</a>.","ieee":"A. Giuliani, É. Lieb, and R. Seiringer, “Formation of stripes and slabs near the ferromagnetic transition,” <i>Communications in Mathematical Physics</i>, vol. 331. Springer, pp. 333–350, 2014."},"department":[{"_id":"RoSe"}],"file":[{"checksum":"c8423271cd1e1ba9e44c47af75efe7b6","relation":"main_file","creator":"dernst","access_level":"open_access","file_id":"11409","date_created":"2022-05-24T08:30:40Z","success":1,"file_name":"2014_CommMathPhysics_Giuliani.pdf","date_updated":"2022-05-24T08:30:40Z","content_type":"application/pdf","file_size":334064}],"oa_version":"Published Version","date_updated":"2022-05-24T08:32:50Z","type":"journal_article","quality_controlled":"1","date_published":"2014-10-01T00:00:00Z","title":"Formation of stripes and slabs near the ferromagnetic transition","article_processing_charge":"No","volume":331,"publication":"Communications in Mathematical Physics","year":"2014","date_created":"2018-12-11T11:54:48Z","ddc":["510"]},{"language":[{"iso":"eng"}],"page":"487 - 495","intvolume":"        25","publisher":"Oxford University Press","day":"13","ec_funded":1,"publication_status":"published","month":"02","doi":"10.1093/beheco/aru002","abstract":[{"text":"The social intelligence hypothesis states that the need to cope with complexities of social life has driven the evolution of advanced cognitive abilities. It is usually invoked in the context of challenges arising from complex intragroup structures, hierarchies, and alliances. However, a fundamental aspect of group living remains largely unexplored as a driving force in cognitive evolution: the competition between individuals searching for resources (producers) and conspecifics that parasitize their findings (scroungers). In populations of social foragers, abilities that enable scroungers to steal by outsmarting producers, and those allowing producers to prevent theft by outsmarting scroungers, are likely to be beneficial and may fuel a cognitive arms race. Using analytical theory and agent-based simulations, we present a general model for such a race that is driven by the producer-scrounger game and show that the race's plausibility is dramatically affected by the nature of the evolving abilities. If scrounging and scrounging avoidance rely on separate, strategy-specific cognitive abilities, arms races are short-lived and have a limited effect on cognition. However, general cognitive abilities that facilitate both scrounging and scrounging avoidance undergo stable, long-lasting arms races. Thus, ubiquitous foraging interactions may lead to the evolution of general cognitive abilities in social animals, without the requirement of complex intragroup structures.","lang":"eng"}],"publist_id":"5157","issue":"3","status":"public","publication":"Behavioral Ecology","volume":25,"year":"2014","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014306/","open_access":"1"}],"date_created":"2018-12-11T11:54:48Z","quality_controlled":"1","project":[{"grant_number":"250152","name":"Limits to selection in biology and in evolutionary computation","call_identifier":"FP7","_id":"25B07788-B435-11E9-9278-68D0E5697425"}],"date_published":"2014-02-13T00:00:00Z","title":"An arms race between producers and scroungers can drive the evolution of social cognition","citation":{"short":"M. Arbilly, D. Weissman, M. Feldman, U. Grodzinski, Behavioral Ecology 25 (2014) 487–495.","ama":"Arbilly M, Weissman D, Feldman M, Grodzinski U. An arms race between producers and scroungers can drive the evolution of social cognition. <i>Behavioral Ecology</i>. 2014;25(3):487-495. doi:<a href=\"https://doi.org/10.1093/beheco/aru002\">10.1093/beheco/aru002</a>","chicago":"Arbilly, Michal, Daniel Weissman, Marcus Feldman, and Uri Grodzinski. “An Arms Race between Producers and Scroungers Can Drive the Evolution of Social Cognition.” <i>Behavioral Ecology</i>. Oxford University Press, 2014. <a href=\"https://doi.org/10.1093/beheco/aru002\">https://doi.org/10.1093/beheco/aru002</a>.","ieee":"M. Arbilly, D. Weissman, M. Feldman, and U. Grodzinski, “An arms race between producers and scroungers can drive the evolution of social cognition,” <i>Behavioral Ecology</i>, vol. 25, no. 3. Oxford University Press, pp. 487–495, 2014.","ista":"Arbilly M, Weissman D, Feldman M, Grodzinski U. 2014. An arms race between producers and scroungers can drive the evolution of social cognition. Behavioral Ecology. 25(3), 487–495.","mla":"Arbilly, Michal, et al. “An Arms Race between Producers and Scroungers Can Drive the Evolution of Social Cognition.” <i>Behavioral Ecology</i>, vol. 25, no. 3, Oxford University Press, 2014, pp. 487–95, doi:<a href=\"https://doi.org/10.1093/beheco/aru002\">10.1093/beheco/aru002</a>.","apa":"Arbilly, M., Weissman, D., Feldman, M., &#38; Grodzinski, U. (2014). An arms race between producers and scroungers can drive the evolution of social cognition. <i>Behavioral Ecology</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/beheco/aru002\">https://doi.org/10.1093/beheco/aru002</a>"},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","oa":1,"author":[{"last_name":"Arbilly","first_name":"Michal","full_name":"Arbilly, Michal"},{"full_name":"Weissman, Daniel","first_name":"Daniel","id":"2D0CE020-F248-11E8-B48F-1D18A9856A87","last_name":"Weissman"},{"last_name":"Feldman","full_name":"Feldman, Marcus","first_name":"Marcus"},{"full_name":"Grodzinski, Uri","first_name":"Uri","last_name":"Grodzinski"}],"oa_version":"Submitted Version","date_updated":"2021-01-12T06:54:11Z","department":[{"_id":"NiBa"}],"type":"journal_article","scopus_import":1,"_id":"1936"},{"publisher":"Springer","language":[{"iso":"eng"}],"intvolume":"       332","page":"261 - 353","issue":"1","abstract":[{"lang":"eng","text":"We prove the edge universality of the beta ensembles for any β ≥ 1, provided that the limiting spectrum is supported on a single interval, and the external potential is C4 and regular. We also prove that the edge universality holds for generalized Wigner matrices for all symmetry classes. Moreover, our results allow us to extend bulk universality for beta ensembles from analytic potentials to potentials in class C4."}],"publist_id":"5158","doi":"10.1007/s00220-014-2120-z","status":"public","publication_status":"published","day":"01","month":"11","title":"Edge universality of beta ensembles","date_published":"2014-11-01T00:00:00Z","project":[{"_id":"25BDE9A4-B435-11E9-9278-68D0E5697425","grant_number":"SFB-TR3-TP10B","name":"Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen"}],"quality_controlled":"1","year":"2014","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1306.5728"}],"volume":332,"publication":"Communications in Mathematical Physics","date_created":"2018-12-11T11:54:48Z","scopus_import":1,"_id":"1937","department":[{"_id":"LaEr"}],"date_updated":"2021-01-12T06:54:12Z","oa_version":"Submitted Version","author":[{"full_name":"Bourgade, Paul","first_name":"Paul","last_name":"Bourgade"},{"last_name":"Erdös","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László","full_name":"Erdös, László","orcid":"0000-0001-5366-9603"},{"full_name":"Yau, Horngtzer","first_name":"Horngtzer","last_name":"Yau"}],"oa":1,"citation":{"ama":"Bourgade P, Erdös L, Yau H. Edge universality of beta ensembles. <i>Communications in Mathematical Physics</i>. 2014;332(1):261-353. doi:<a href=\"https://doi.org/10.1007/s00220-014-2120-z\">10.1007/s00220-014-2120-z</a>","short":"P. Bourgade, L. Erdös, H. Yau, Communications in Mathematical Physics 332 (2014) 261–353.","chicago":"Bourgade, Paul, László Erdös, and Horngtzer Yau. “Edge Universality of Beta Ensembles.” <i>Communications in Mathematical Physics</i>. Springer, 2014. <a href=\"https://doi.org/10.1007/s00220-014-2120-z\">https://doi.org/10.1007/s00220-014-2120-z</a>.","ieee":"P. Bourgade, L. Erdös, and H. Yau, “Edge universality of beta ensembles,” <i>Communications in Mathematical Physics</i>, vol. 332, no. 1. Springer, pp. 261–353, 2014.","ista":"Bourgade P, Erdös L, Yau H. 2014. Edge universality of beta ensembles. Communications in Mathematical Physics. 332(1), 261–353.","mla":"Bourgade, Paul, et al. “Edge Universality of Beta Ensembles.” <i>Communications in Mathematical Physics</i>, vol. 332, no. 1, Springer, 2014, pp. 261–353, doi:<a href=\"https://doi.org/10.1007/s00220-014-2120-z\">10.1007/s00220-014-2120-z</a>.","apa":"Bourgade, P., Erdös, L., &#38; Yau, H. (2014). Edge universality of beta ensembles. <i>Communications in Mathematical Physics</i>. Springer. <a href=\"https://doi.org/10.1007/s00220-014-2120-z\">https://doi.org/10.1007/s00220-014-2120-z</a>"},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","type":"journal_article"},{"publisher":"American Physical Society","language":[{"iso":"eng"}],"article_number":"243601","intvolume":"       113","issue":"24","doi":"10.1103/PhysRevLett.113.243601","abstract":[{"lang":"eng","text":"Optical transport represents a natural route towards fast communications, and it is currently used in large scale data transfer. The progressive miniaturization of devices for information processing calls for the microscopic tailoring of light transport and confinement at length scales appropriate for upcoming technologies. With this goal in mind, we present a theoretical analysis of a one-dimensional Fabry-Perot interferometer built with two highly saturable nonlinear mirrors: a pair of two-level systems. Our approach captures nonlinear and nonreciprocal effects of light transport that were not reported previously. Remarkably, we show that such an elementary device can operate as a microscopic integrated optical rectifier."}],"publist_id":"5085","status":"public","publication_status":"published","day":"08","ec_funded":1,"month":"12","project":[{"name":"International IST Postdoc Fellowship Programme","grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425","call_identifier":"FP7"}],"title":"Fabry-Perot interferometer with quantum mirrors: Nonlinear light transport and rectification","date_published":"2014-12-08T00:00:00Z","quality_controlled":"1","main_file_link":[{"url":"http://arxiv.org/abs/1410.5972","open_access":"1"}],"year":"2014","publication":"Physical Review Letters","volume":113,"date_created":"2018-12-11T11:55:06Z","scopus_import":1,"_id":"1995","date_updated":"2021-01-12T06:54:34Z","oa_version":"Submitted Version","department":[{"_id":"MiLe"}],"citation":{"ista":"Fratini F, Mascarenhas E, Safari L, Poizat J, Valente D, Auffèves A, Gerace D, Santos M. 2014. Fabry-Perot interferometer with quantum mirrors: Nonlinear light transport and rectification. Physical Review Letters. 113(24), 243601.","apa":"Fratini, F., Mascarenhas, E., Safari, L., Poizat, J., Valente, D., Auffèves, A., … Santos, M. (2014). Fabry-Perot interferometer with quantum mirrors: Nonlinear light transport and rectification. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.113.243601\">https://doi.org/10.1103/PhysRevLett.113.243601</a>","mla":"Fratini, Filippo, et al. “Fabry-Perot Interferometer with Quantum Mirrors: Nonlinear Light Transport and Rectification.” <i>Physical Review Letters</i>, vol. 113, no. 24, 243601, American Physical Society, 2014, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.113.243601\">10.1103/PhysRevLett.113.243601</a>.","ama":"Fratini F, Mascarenhas E, Safari L, et al. Fabry-Perot interferometer with quantum mirrors: Nonlinear light transport and rectification. <i>Physical Review Letters</i>. 2014;113(24). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.113.243601\">10.1103/PhysRevLett.113.243601</a>","short":"F. Fratini, E. Mascarenhas, L. Safari, J. Poizat, D. Valente, A. Auffèves, D. Gerace, M. Santos, Physical Review Letters 113 (2014).","chicago":"Fratini, Filippo, Eduardo Mascarenhas, Laleh Safari, Jean Poizat, Daniel Valente, Alexia Auffèves, Dario Gerace, and Marcelo Santos. “Fabry-Perot Interferometer with Quantum Mirrors: Nonlinear Light Transport and Rectification.” <i>Physical Review Letters</i>. American Physical Society, 2014. <a href=\"https://doi.org/10.1103/PhysRevLett.113.243601\">https://doi.org/10.1103/PhysRevLett.113.243601</a>.","ieee":"F. Fratini <i>et al.</i>, “Fabry-Perot interferometer with quantum mirrors: Nonlinear light transport and rectification,” <i>Physical Review Letters</i>, vol. 113, no. 24. American Physical Society, 2014."},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Fratini","first_name":"Filippo","full_name":"Fratini, Filippo"},{"full_name":"Mascarenhas, Eduardo","first_name":"Eduardo","last_name":"Mascarenhas"},{"first_name":"Laleh","full_name":"Safari, Laleh","id":"3C325E5E-F248-11E8-B48F-1D18A9856A87","last_name":"Safari"},{"first_name":"Jean","full_name":"Poizat, Jean","last_name":"Poizat"},{"last_name":"Valente","first_name":"Daniel","full_name":"Valente, Daniel"},{"last_name":"Auffèves","first_name":"Alexia","full_name":"Auffèves, Alexia"},{"full_name":"Gerace, Dario","first_name":"Dario","last_name":"Gerace"},{"full_name":"Santos, Marcelo","first_name":"Marcelo","last_name":"Santos"}],"oa":1,"type":"journal_article"},{"status":"public","_id":"1996","issue":"50","abstract":[{"lang":"eng","text":"Auxin polar transport, local maxima, and gradients have become an importantmodel system for studying self-organization. Auxin distribution is regulated by auxin-dependent positive feedback loops that are not well-understood at the molecular level. Previously, we showed the involvement of the RHO of Plants (ROP) effector INTERACTOR of CONSTITUTIVELY active ROP 1 (ICR1) in regulation of auxin transport and that ICR1 levels are posttranscriptionally repressed at the site of maximum auxin accumulation at the root tip. Here, we show that bimodal regulation of ICR1 levels by auxin is essential for regulating formation of auxin local maxima and gradients. ICR1 levels increase concomitant with increase in auxin response in lateral root primordia, cotyledon tips, and provascular tissues. However, in the embryo hypophysis and root meristem, when auxin exceeds critical levels, ICR1 is rapidly destabilized by an SCF(TIR1/AFB) [SKP, Cullin, F-box (transport inhibitor response 1/auxin signaling F-box protein)]-dependent auxin signaling mechanism. Furthermore, ectopic expression of ICR1 in the embryo hypophysis resulted in reduction of auxin accumulation and concomitant root growth arrest. ICR1 disappeared during root regeneration and lateral root initiation concomitantly with the formation of a local auxin maximum in response to external auxin treatments and transiently after gravitropic stimulation. Destabilization of ICR1 was impaired after inhibition of auxin transport and signaling, proteasome function, and protein synthesis. A mathematical model based on these findings shows that an in vivo-like auxin distribution, rootward auxin flux, and shootward reflux can be simulated without assuming preexisting tissue polarity. Our experimental results and mathematical modeling indicate that regulation of auxin distribution is tightly associated with auxin-dependent ICR1 levels."}],"doi":"10.1073/pnas.1413918111","publist_id":"5083","scopus_import":1,"type":"journal_article","month":"12","date_updated":"2021-01-12T06:54:35Z","publication_status":"published","oa_version":"Submitted Version","department":[{"_id":"JiFr"}],"day":"16","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","citation":{"apa":"Hazak, O., Obolski, U., Prat, T., Friml, J., Hadany, L., &#38; Yalovsky, S. (2014). Bimodal regulation of ICR1 levels generates self-organizing auxin distribution. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1413918111\">https://doi.org/10.1073/pnas.1413918111</a>","mla":"Hazak, Ora, et al. “Bimodal Regulation of ICR1 Levels Generates Self-Organizing Auxin Distribution.” <i>PNAS</i>, vol. 111, no. 50, National Academy of Sciences, 2014, pp. E5471–79, doi:<a href=\"https://doi.org/10.1073/pnas.1413918111\">10.1073/pnas.1413918111</a>.","ista":"Hazak O, Obolski U, Prat T, Friml J, Hadany L, Yalovsky S. 2014. Bimodal regulation of ICR1 levels generates self-organizing auxin distribution. PNAS. 111(50), E5471–E5479.","ieee":"O. Hazak, U. Obolski, T. Prat, J. Friml, L. Hadany, and S. Yalovsky, “Bimodal regulation of ICR1 levels generates self-organizing auxin distribution,” <i>PNAS</i>, vol. 111, no. 50. National Academy of Sciences, pp. E5471–E5479, 2014.","chicago":"Hazak, Ora, Uri Obolski, Tomas Prat, Jiří Friml, Lilach Hadany, and Shaul Yalovsky. “Bimodal Regulation of ICR1 Levels Generates Self-Organizing Auxin Distribution.” <i>PNAS</i>. National Academy of Sciences, 2014. <a href=\"https://doi.org/10.1073/pnas.1413918111\">https://doi.org/10.1073/pnas.1413918111</a>.","ama":"Hazak O, Obolski U, Prat T, Friml J, Hadany L, Yalovsky S. Bimodal regulation of ICR1 levels generates self-organizing auxin distribution. <i>PNAS</i>. 2014;111(50):E5471-E5479. doi:<a href=\"https://doi.org/10.1073/pnas.1413918111\">10.1073/pnas.1413918111</a>","short":"O. Hazak, U. Obolski, T. Prat, J. Friml, L. Hadany, S. Yalovsky, PNAS 111 (2014) E5471–E5479."},"author":[{"last_name":"Hazak","full_name":"Hazak, Ora","first_name":"Ora"},{"first_name":"Uri","full_name":"Obolski, Uri","last_name":"Obolski"},{"last_name":"Prat","id":"3DA3BFEE-F248-11E8-B48F-1D18A9856A87","first_name":"Tomas","full_name":"Prat, Tomas"},{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří","last_name":"Friml"},{"last_name":"Hadany","first_name":"Lilach","full_name":"Hadany, Lilach"},{"first_name":"Shaul","full_name":"Yalovsky, Shaul","last_name":"Yalovsky"}],"oa":1,"publisher":"National Academy of Sciences","date_published":"2014-12-16T00:00:00Z","title":"Bimodal regulation of ICR1 levels generates self-organizing auxin distribution","quality_controlled":"1","intvolume":"       111","date_created":"2018-12-11T11:55:07Z","page":"E5471 - E5479","main_file_link":[{"open_access":"1","url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273421/"}],"year":"2014","publication":"PNAS","language":[{"iso":"eng"}],"volume":111},{"publication_status":"published","day":"19","ec_funded":1,"month":"11","issue":"11","publist_id":"5074","abstract":[{"lang":"eng","text":"Oriens-lacunosum moleculare (O-LM) interneurons in the CA1 region of the hippocampus play a key role in feedback inhibition and in the control of network activity. However, how these cells are efficiently activated in the network remains unclear. To address this question, I performed recordings from CA1 pyramidal neuron axons, the presynaptic fibers that provide feedback innervation of these interneurons. Two forms of axonal action potential (AP) modulation were identified. First, repetitive stimulation resulted in activity-dependent AP broadening. Broadening showed fast onset, with marked changes in AP shape following a single AP. Second, tonic depolarization in CA1 pyramidal neuron somata induced AP broadening in the axon, and depolarization-induced broadening summated with activity-dependent broadening. Outsideout patch recordings from CA1 pyramidal neuron axons revealed a high density of a-dendrotoxin (α-DTX)-sensitive, inactivating K+ channels, suggesting that K+ channel inactivation mechanistically contributes to AP broadening. To examine the functional consequences of axonal AP modulation for synaptic transmission, I performed paired recordings between synaptically connected CA1 pyramidal neurons and O-LM interneurons. CA1 pyramidal neuron-O-LM interneuron excitatory postsynaptic currents (EPSCs) showed facilitation during both repetitive stimulation and tonic depolarization of the presynaptic neuron. Both effects were mimicked and occluded by α-DTX, suggesting that they were mediated by K+ channel inactivation. Therefore, axonal AP modulation can greatly facilitate the activation of O-LM interneurons. In conclusion, modulation of AP shape in CA1 pyramidal neuron axons substantially enhances the efficacy of principal neuron-interneuron synapses, promoting the activation of O-LM interneurons in recurrent inhibitory microcircuits."}],"doi":"10.1371/journal.pone.0113124","status":"public","language":[{"iso":"eng"}],"article_number":"0113124","intvolume":"         9","publisher":"Public Library of Science","date_updated":"2021-01-12T06:54:39Z","oa_version":"Published Version","department":[{"_id":"PeJo"}],"file":[{"creator":"system","relation":"main_file","checksum":"85e4f4ea144f827272aaf376b2830564","date_created":"2018-12-12T10:14:52Z","file_id":"5107","access_level":"open_access","file_size":5179993,"content_type":"application/pdf","date_updated":"2020-07-14T12:45:24Z","file_name":"IST-2016-434-v1+1_journal.pone.0113124.pdf"}],"has_accepted_license":"1","citation":{"ista":"Kim S. 2014. Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus. PLoS One. 9(11), 0113124.","mla":"Kim, Sooyun. “Action Potential Modulation in CA1 Pyramidal Neuron Axons Facilitates OLM Interneuron Activation in Recurrent Inhibitory Microcircuits of Rat Hippocampus.” <i>PLoS One</i>, vol. 9, no. 11, 0113124, Public Library of Science, 2014, doi:<a href=\"https://doi.org/10.1371/journal.pone.0113124\">10.1371/journal.pone.0113124</a>.","apa":"Kim, S. (2014). Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0113124\">https://doi.org/10.1371/journal.pone.0113124</a>","short":"S. Kim, PLoS One 9 (2014).","ama":"Kim S. Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus. <i>PLoS One</i>. 2014;9(11). doi:<a href=\"https://doi.org/10.1371/journal.pone.0113124\">10.1371/journal.pone.0113124</a>","chicago":"Kim, Sooyun. “Action Potential Modulation in CA1 Pyramidal Neuron Axons Facilitates OLM Interneuron Activation in Recurrent Inhibitory Microcircuits of Rat Hippocampus.” <i>PLoS One</i>. Public Library of Science, 2014. <a href=\"https://doi.org/10.1371/journal.pone.0113124\">https://doi.org/10.1371/journal.pone.0113124</a>.","ieee":"S. Kim, “Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus,” <i>PLoS One</i>, vol. 9, no. 11. Public Library of Science, 2014."},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","oa":1,"author":[{"id":"394AB1C8-F248-11E8-B48F-1D18A9856A87","first_name":"Sooyun","full_name":"Kim, Sooyun","last_name":"Kim"}],"pubrep_id":"434","type":"journal_article","file_date_updated":"2020-07-14T12:45:24Z","scopus_import":1,"_id":"2002","year":"2014","publication":"PLoS One","volume":9,"ddc":["570"],"date_created":"2018-12-11T11:55:09Z","project":[{"grant_number":"268548","name":"Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons","call_identifier":"FP7","_id":"25C0F108-B435-11E9-9278-68D0E5697425"}],"date_published":"2014-11-19T00:00:00Z","title":"Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus","quality_controlled":"1","tmp":{"name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png"}},{"_id":"2004","scopus_import":1,"file_date_updated":"2020-07-14T12:45:24Z","type":"journal_article","pubrep_id":"435","author":[{"first_name":"Anna","full_name":"Lovrics, Anna","last_name":"Lovrics"},{"last_name":"Gao","full_name":"Gao, Yu","first_name":"Yu"},{"last_name":"Juhász","first_name":"Bianka","full_name":"Juhász, Bianka"},{"first_name":"István","full_name":"Bock, István","last_name":"Bock"},{"last_name":"Byrne","first_name":"Helen","full_name":"Byrne, Helen"},{"last_name":"Dinnyés","first_name":"András","full_name":"Dinnyés, András"},{"last_name":"Kovács","full_name":"Kovács, Krisztián","first_name":"Krisztián","id":"2AB5821E-F248-11E8-B48F-1D18A9856A87"}],"oa":1,"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","citation":{"ieee":"A. Lovrics <i>et al.</i>, “Boolean modelling reveals new regulatory connections between transcription factors orchestrating the development of the ventral spinal cord,” <i>PLoS One</i>, vol. 9, no. 11. Public Library of Science, 2014.","ama":"Lovrics A, Gao Y, Juhász B, et al. Boolean modelling reveals new regulatory connections between transcription factors orchestrating the development of the ventral spinal cord. <i>PLoS One</i>. 2014;9(11). doi:<a href=\"https://doi.org/10.1371/journal.pone.0111430\">10.1371/journal.pone.0111430</a>","short":"A. Lovrics, Y. Gao, B. Juhász, I. Bock, H. Byrne, A. Dinnyés, K. Kovács, PLoS One 9 (2014).","chicago":"Lovrics, Anna, Yu Gao, Bianka Juhász, István Bock, Helen Byrne, András Dinnyés, and Krisztián Kovács. “Boolean Modelling Reveals New Regulatory Connections between Transcription Factors Orchestrating the Development of the Ventral Spinal Cord.” <i>PLoS One</i>. Public Library of Science, 2014. <a href=\"https://doi.org/10.1371/journal.pone.0111430\">https://doi.org/10.1371/journal.pone.0111430</a>.","ista":"Lovrics A, Gao Y, Juhász B, Bock I, Byrne H, Dinnyés A, Kovács K. 2014. Boolean modelling reveals new regulatory connections between transcription factors orchestrating the development of the ventral spinal cord. PLoS One. 9(11), e111430.","apa":"Lovrics, A., Gao, Y., Juhász, B., Bock, I., Byrne, H., Dinnyés, A., &#38; Kovács, K. (2014). Boolean modelling reveals new regulatory connections between transcription factors orchestrating the development of the ventral spinal cord. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0111430\">https://doi.org/10.1371/journal.pone.0111430</a>","mla":"Lovrics, Anna, et al. “Boolean Modelling Reveals New Regulatory Connections between Transcription Factors Orchestrating the Development of the Ventral Spinal Cord.” <i>PLoS One</i>, vol. 9, no. 11, e111430, Public Library of Science, 2014, doi:<a href=\"https://doi.org/10.1371/journal.pone.0111430\">10.1371/journal.pone.0111430</a>."},"department":[{"_id":"JoCs"}],"file":[{"creator":"system","relation":"main_file","checksum":"a2289b843f7463eb1233f9ce45e6a943","file_size":829363,"date_updated":"2020-07-14T12:45:24Z","content_type":"application/pdf","file_name":"IST-2016-435-v1+1_journal.pone.0111430.pdf","date_created":"2018-12-12T10:10:58Z","file_id":"4850","access_level":"open_access"}],"oa_version":"Published Version","date_updated":"2023-02-23T14:06:14Z","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"quality_controlled":"1","title":"Boolean modelling reveals new regulatory connections between transcription factors orchestrating the development of the ventral spinal cord","date_published":"2014-11-14T00:00:00Z","project":[{"name":"International IST Postdoc Fellowship Programme","grant_number":"291734","call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"date_created":"2018-12-11T11:55:09Z","ddc":["570"],"volume":9,"publication":"PLoS One","year":"2014","status":"public","publist_id":"5072","abstract":[{"lang":"eng","text":"We have assembled a network of cell-fate determining transcription factors that play a key role in the specification of the ventral neuronal subtypes of the spinal cord on the basis of published transcriptional interactions. Asynchronous Boolean modelling of the network was used to compare simulation results with reported experimental observations. Such comparison highlighted the need to include additional regulatory connections in order to obtain the fixed point attractors of the model associated with the five known progenitor cell types located in the ventral spinal cord. The revised gene regulatory network reproduced previously observed cell state switches between progenitor cells observed in knock-out animal models or in experiments where the transcription factors were overexpressed. Furthermore the network predicted the inhibition of Irx3 by Nkx2.2 and this prediction was tested experimentally. Our results provide evidence for the existence of an as yet undescribed inhibitory connection which could potentially have significance beyond the ventral spinal cord. The work presented in this paper demonstrates the strength of Boolean modelling for identifying gene regulatory networks."}],"doi":"10.1371/journal.pone.0111430","issue":"11","month":"11","related_material":{"record":[{"status":"public","relation":"research_data","id":"9722"}]},"ec_funded":1,"day":"14","publication_status":"published","publisher":"Public Library of Science","intvolume":"         9","article_number":"e111430","language":[{"iso":"eng"}]},{"date_created":"2018-12-11T11:55:10Z","main_file_link":[{"url":"https://CRAN.R-project.org/package=gIPFrm ","open_access":"1"}],"year":"2014","article_processing_charge":"No","publisher":"The Comprehensive R Archive Network","title":"gIPFrm: Generalized iterative proportional fitting for relational models","date_published":"2014-03-20T00:00:00Z","type":"research_data_reference","month":"03","oa_version":"Published Version","date_updated":"2022-08-26T08:12:12Z","department":[{"_id":"CaUh"}],"citation":{"ista":"Klimova A, Rudas T. 2014. gIPFrm: Generalized iterative proportional fitting for relational models, The Comprehensive R Archive Network.","apa":"Klimova, A., &#38; Rudas, T. (2014). gIPFrm: Generalized iterative proportional fitting for relational models. The Comprehensive R Archive Network.","mla":"Klimova, Anna, and Tamás Rudas. <i>GIPFrm: Generalized Iterative Proportional Fitting for Relational Models</i>. The Comprehensive R Archive Network, 2014.","short":"A. Klimova, T. Rudas, (2014).","ama":"Klimova A, Rudas T. gIPFrm: Generalized iterative proportional fitting for relational models. 2014.","chicago":"Klimova, Anna, and Tamás Rudas. “GIPFrm: Generalized Iterative Proportional Fitting for Relational Models.” The Comprehensive R Archive Network, 2014.","ieee":"A. Klimova and T. Rudas, “gIPFrm: Generalized iterative proportional fitting for relational models.” The Comprehensive R Archive Network, 2014."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"20","author":[{"last_name":"Klimova","id":"31934120-F248-11E8-B48F-1D18A9856A87","first_name":"Anna","full_name":"Klimova, Anna"},{"last_name":"Rudas","full_name":"Rudas, Tamás","first_name":"Tamás"}],"oa":1,"status":"public","_id":"2007","abstract":[{"text":"Maximum likelihood estimation under relational models, with or without the overall effect. For more information see the reference manual","lang":"eng"}],"publist_id":"5069"},{"author":[{"last_name":"Yu","first_name":"Fei","full_name":"Yu, Fei"},{"full_name":"Fienberg, Stephen","first_name":"Stephen","last_name":"Fienberg"},{"last_name":"Slaković","first_name":"Alexandra","full_name":"Slaković, Alexandra"},{"last_name":"Uhler","first_name":"Caroline","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","full_name":"Uhler, Caroline","orcid":"0000-0002-7008-0216"}],"oa":1,"day":"01","citation":{"chicago":"Yu, Fei, Stephen Fienberg, Alexandra Slaković, and Caroline Uhler. “Scalable Privacy-Preserving Data Sharing Methodology for Genome-Wide Association Studies.” <i>Journal of Biomedical Informatics</i>. Elsevier, 2014. <a href=\"https://doi.org/10.1016/j.jbi.2014.01.008\">https://doi.org/10.1016/j.jbi.2014.01.008</a>.","short":"F. Yu, S. Fienberg, A. Slaković, C. Uhler, Journal of Biomedical Informatics 50 (2014) 133–141.","ama":"Yu F, Fienberg S, Slaković A, Uhler C. Scalable privacy-preserving data sharing methodology for genome-wide association studies. <i>Journal of Biomedical Informatics</i>. 2014;50:133-141. doi:<a href=\"https://doi.org/10.1016/j.jbi.2014.01.008\">10.1016/j.jbi.2014.01.008</a>","ieee":"F. Yu, S. Fienberg, A. Slaković, and C. Uhler, “Scalable privacy-preserving data sharing methodology for genome-wide association studies,” <i>Journal of Biomedical Informatics</i>, vol. 50. Elsevier, pp. 133–141, 2014.","apa":"Yu, F., Fienberg, S., Slaković, A., &#38; Uhler, C. (2014). Scalable privacy-preserving data sharing methodology for genome-wide association studies. <i>Journal of Biomedical Informatics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jbi.2014.01.008\">https://doi.org/10.1016/j.jbi.2014.01.008</a>","mla":"Yu, Fei, et al. “Scalable Privacy-Preserving Data Sharing Methodology for Genome-Wide Association Studies.” <i>Journal of Biomedical Informatics</i>, vol. 50, Elsevier, 2014, pp. 133–41, doi:<a href=\"https://doi.org/10.1016/j.jbi.2014.01.008\">10.1016/j.jbi.2014.01.008</a>.","ista":"Yu F, Fienberg S, Slaković A, Uhler C. 2014. Scalable privacy-preserving data sharing methodology for genome-wide association studies. Journal of Biomedical Informatics. 50, 133–141."},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"CaUh"}],"acknowledgement":"This research was partially supported by NSF Awards EMSW21-RTG and BCS-0941518 to the Department of Statistics at Carnegie Mellon University, and by NSF Grant BCS-0941553 to the Department of Statistics at Pennsylvania State University. This work was also supported in part by the National Center for Research Resources, Grant UL1 RR033184, and is now at the National Center for Advancing Translational Sciences, Grant UL1 TR000127 to Pennsylvania State University. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NSF and NIH.","publication_status":"published","oa_version":"Submitted Version","date_updated":"2021-01-12T06:54:42Z","month":"08","type":"journal_article","scopus_import":1,"abstract":[{"text":"The protection of privacy of individual-level information in genome-wide association study (GWAS) databases has been a major concern of researchers following the publication of “an attack” on GWAS data by Homer et al. (2008). Traditional statistical methods for confidentiality and privacy protection of statistical databases do not scale well to deal with GWAS data, especially in terms of guarantees regarding protection from linkage to external information. The more recent concept of differential privacy, introduced by the cryptographic community, is an approach that provides a rigorous definition of privacy with meaningful privacy guarantees in the presence of arbitrary external information, although the guarantees may come at a serious price in terms of data utility. Building on such notions, Uhler et al. (2013) proposed new methods to release aggregate GWAS data without compromising an individual’s privacy. We extend the methods developed in Uhler et al. (2013) for releasing differentially-private χ2χ2-statistics by allowing for arbitrary number of cases and controls, and for releasing differentially-private allelic test statistics. We also provide a new interpretation by assuming the controls’ data are known, which is a realistic assumption because some GWAS use publicly available data as controls. We assess the performance of the proposed methods through a risk-utility analysis on a real data set consisting of DNA samples collected by the Wellcome Trust Case Control Consortium and compare the methods with the differentially-private release mechanism proposed by Johnson and Shmatikov (2013).","lang":"eng"}],"doi":"10.1016/j.jbi.2014.01.008","publist_id":"5065","_id":"2011","status":"public","volume":50,"language":[{"iso":"eng"}],"publication":"Journal of Biomedical Informatics","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1401.5193"}],"year":"2014","page":"133 - 141","intvolume":"        50","date_created":"2018-12-11T11:55:12Z","quality_controlled":"1","date_published":"2014-08-01T00:00:00Z","title":"Scalable privacy-preserving data sharing methodology for genome-wide association studies","publisher":"Elsevier"},{"date_created":"2018-12-11T11:55:12Z","article_number":"1401.0468","main_file_link":[{"url":"http://cccg.ca/proceedings/2014/papers/paper23.pdf","open_access":"1"}],"year":"2014","article_processing_charge":"No","arxiv":1,"language":[{"iso":"eng"}],"publication":"arXiv","title":"Sphere packing with limited overlap","date_published":"2014-01-01T00:00:00Z","month":"01","type":"preprint","department":[{"_id":"HeEd"},{"_id":"CaUh"}],"date_updated":"2023-10-18T08:06:45Z","acknowledgement":"We thank Herbert Edelsbrunner for his valuable discussions and ideas on the topic of this paper.  The second author has been supported by the Max Planck Center for Visual Computing and Communication","oa_version":"Submitted Version","publication_status":"submitted","oa":1,"author":[{"id":"41B58C0C-F248-11E8-B48F-1D18A9856A87","first_name":"Mabel","full_name":"Iglesias Ham, Mabel","last_name":"Iglesias Ham"},{"last_name":"Kerber","first_name":"Michael","full_name":"Kerber, Michael","orcid":"0000-0002-8030-9299"},{"orcid":"0000-0002-7008-0216","first_name":"Caroline","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","full_name":"Uhler, Caroline","last_name":"Uhler"}],"day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Iglesias Ham, Mabel, et al. “Sphere Packing with Limited Overlap.” <i>ArXiv</i>, 1401.0468, doi:<a href=\"https://doi.org/10.48550/arXiv.1401.0468\">10.48550/arXiv.1401.0468</a>.","apa":"Iglesias Ham, M., Kerber, M., &#38; Uhler, C. (n.d.). Sphere packing with limited overlap. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.1401.0468\">https://doi.org/10.48550/arXiv.1401.0468</a>","ista":"Iglesias Ham M, Kerber M, Uhler C. Sphere packing with limited overlap. arXiv, 1401.0468.","chicago":"Iglesias Ham, Mabel, Michael Kerber, and Caroline Uhler. “Sphere Packing with Limited Overlap.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.1401.0468\">https://doi.org/10.48550/arXiv.1401.0468</a>.","ama":"Iglesias Ham M, Kerber M, Uhler C. Sphere packing with limited overlap. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.1401.0468\">10.48550/arXiv.1401.0468</a>","short":"M. Iglesias Ham, M. Kerber, C. Uhler, ArXiv (n.d.).","ieee":"M. Iglesias Ham, M. Kerber, and C. Uhler, “Sphere packing with limited overlap,” <i>arXiv</i>. ."},"_id":"2012","status":"public","external_id":{"arxiv":["1401.0468"]},"doi":"10.48550/arXiv.1401.0468","abstract":[{"text":"The classical sphere packing problem asks for the best (infinite) arrangement of non-overlapping unit balls which cover as much space as possible. We define a generalized version of the problem, where we allow each ball a limited amount of overlap with other balls. We study two natural choices of overlap measures and obtain the optimal lattice packings in a parameterized family of lattices which contains the FCC, BCC, and integer lattice.","lang":"eng"}],"publist_id":"5064"},{"_id":"2013","scopus_import":1,"type":"journal_article","oa":1,"author":[{"last_name":"Lin","first_name":"Shaowei","full_name":"Lin, Shaowei"},{"first_name":"Caroline","full_name":"Uhler, Caroline","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7008-0216","last_name":"Uhler"},{"first_name":"Bernd","full_name":"Sturmfels, Bernd","last_name":"Sturmfels"},{"last_name":"Bühlmann","first_name":"Peter","full_name":"Bühlmann, Peter"}],"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","citation":{"ieee":"S. Lin, C. Uhler, B. Sturmfels, and P. Bühlmann, “Hypersurfaces and their singularities in partial correlation testing,” <i>Foundations of Computational Mathematics</i>, vol. 14, no. 5. Springer, pp. 1079–1116, 2014.","ama":"Lin S, Uhler C, Sturmfels B, Bühlmann P. Hypersurfaces and their singularities in partial correlation testing. <i>Foundations of Computational Mathematics</i>. 2014;14(5):1079-1116. doi:<a href=\"https://doi.org/10.1007/s10208-014-9205-0\">10.1007/s10208-014-9205-0</a>","short":"S. Lin, C. Uhler, B. Sturmfels, P. Bühlmann, Foundations of Computational Mathematics 14 (2014) 1079–1116.","chicago":"Lin, Shaowei, Caroline Uhler, Bernd Sturmfels, and Peter Bühlmann. “Hypersurfaces and Their Singularities in Partial Correlation Testing.” <i>Foundations of Computational Mathematics</i>. Springer, 2014. <a href=\"https://doi.org/10.1007/s10208-014-9205-0\">https://doi.org/10.1007/s10208-014-9205-0</a>.","ista":"Lin S, Uhler C, Sturmfels B, Bühlmann P. 2014. Hypersurfaces and their singularities in partial correlation testing. Foundations of Computational Mathematics. 14(5), 1079–1116.","mla":"Lin, Shaowei, et al. “Hypersurfaces and Their Singularities in Partial Correlation Testing.” <i>Foundations of Computational Mathematics</i>, vol. 14, no. 5, Springer, 2014, pp. 1079–116, doi:<a href=\"https://doi.org/10.1007/s10208-014-9205-0\">10.1007/s10208-014-9205-0</a>.","apa":"Lin, S., Uhler, C., Sturmfels, B., &#38; Bühlmann, P. (2014). Hypersurfaces and their singularities in partial correlation testing. <i>Foundations of Computational Mathematics</i>. Springer. <a href=\"https://doi.org/10.1007/s10208-014-9205-0\">https://doi.org/10.1007/s10208-014-9205-0</a>"},"department":[{"_id":"CaUh"}],"date_updated":"2021-01-12T06:54:43Z","oa_version":"Submitted Version","quality_controlled":"1","date_published":"2014-10-10T00:00:00Z","title":"Hypersurfaces and their singularities in partial correlation testing","date_created":"2018-12-11T11:55:12Z","volume":14,"publication":"Foundations of Computational Mathematics","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1209.0285"}],"year":"2014","status":"public","publist_id":"5063","abstract":[{"lang":"eng","text":"An asymptotic theory is developed for computing volumes of regions in the parameter space of a directed Gaussian graphical model that are obtained by bounding partial correlations. We study these volumes using the method of real log canonical thresholds from algebraic geometry. Our analysis involves the computation of the singular loci of correlation hypersurfaces. Statistical applications include the strong-faithfulness assumption for the PC algorithm and the quantification of confounder bias in causal inference. A detailed analysis is presented for trees, bow ties, tripartite graphs, and complete graphs.\r\n"}],"doi":"10.1007/s10208-014-9205-0","issue":"5","month":"10","day":"10","publication_status":"published","acknowledgement":"This work was supported in part by the US National Science Foundation (DMS-0968882) and the Defense Advanced Research Projects Agency (DARPA) Deep Learning program (FA8650-10-C-7020).","publisher":"Springer","page":"1079 - 1116","intvolume":"        14","language":[{"iso":"eng"}]},{"date_created":"2018-12-11T11:55:14Z","publication":"ArXiv","year":"2014","main_file_link":[{"url":"http://arxiv.org/abs/1406.4901","open_access":"1"}],"publisher":"ArXiv","quality_controlled":0,"date_published":"2014-06-18T00:00:00Z","title":" Exact formulas for the normalizing constants of Wishart distributions for graphical models","month":"06","type":"preprint","oa":1,"extern":1,"author":[{"orcid":"0000-0002-7008-0216","full_name":"Caroline Uhler","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","first_name":"Caroline","last_name":"Uhler"},{"last_name":"Lenkoski","first_name":"Alex","full_name":"Lenkoski, Alex"},{"first_name":"Donald","full_name":"Richards, Donald","last_name":"Richards"}],"citation":{"apa":"Uhler, C., Lenkoski, A., &#38; Richards, D. (2014).  Exact formulas for the normalizing constants of Wishart distributions for graphical models. <i>ArXiv</i>. ArXiv.","mla":"Uhler, Caroline, et al. “ Exact Formulas for the Normalizing Constants of Wishart Distributions for Graphical Models.” <i>ArXiv</i>, ArXiv, 2014.","ista":"Uhler C, Lenkoski A, Richards D. 2014.  Exact formulas for the normalizing constants of Wishart distributions for graphical models. ArXiv, .","ieee":"C. Uhler, A. Lenkoski, and D. Richards, “ Exact formulas for the normalizing constants of Wishart distributions for graphical models,” <i>ArXiv</i>. ArXiv, 2014.","chicago":"Uhler, Caroline, Alex Lenkoski, and Donald Richards. “ Exact Formulas for the Normalizing Constants of Wishart Distributions for Graphical Models.” <i>ArXiv</i>. ArXiv, 2014.","short":"C. Uhler, A. Lenkoski, D. Richards, ArXiv (2014).","ama":"Uhler C, Lenkoski A, Richards D.  Exact formulas for the normalizing constants of Wishart distributions for graphical models. <i>ArXiv</i>. 2014."},"day":"18","acknowledgement":"A.L.'s research was supported by Statistics for Innovation sfi2 in Oslo.\nD.R.'s research was partially supported by the U.S. National Science Foun-dation grant DMS-1309808; and by a Romberg Guest Professorship at the Heidelberg University Graduate School for Mathematical and Computational Methods in the Sciences, funded by German Universities Excellence Initiative grant GSC 220/2.","date_updated":"2021-01-12T06:54:44Z","publication_status":"published","_id":"2017","status":"public","publist_id":"5058","abstract":[{"lang":"eng","text":"     Gaussian graphical models have received considerable attention during the past four decades from the statistical and machine learning communities. In Bayesian treatments of this model, the G-Wishart distribution serves as the conjugate prior for inverse covariance matrices satisfying graphical constraints. While it is straightforward to posit the unnormalized densities, the normalizing constants of these distributions have been known only for graphs that are chordal, or decomposable. Up until now, it was unknown whether the normalizing constant for a general graph could be represented explicitly, and a considerable body of computational literature emerged that attempted to avoid this apparent intractability. We close this question by providing an explicit representation of the G-Wishart normalizing constant for general graphs."}]},{"publication_status":"published","acknowledgement":"This work was supported by “Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program)” initiated by the Council for Science and Technology Policy.","day":"19","month":"11","issue":"47","abstract":[{"lang":"eng","text":"Synaptic cell adhesion molecules are increasingly gaining attention for conferring specific properties to individual synapses. Netrin-G1 and netrin-G2 are trans-synaptic adhesion molecules that distribute on distinct axons, and their presence restricts the expression of their cognate receptors, NGL1 and NGL2, respectively, to specific subdendritic segments of target neurons. However, the neural circuits and functional roles of netrin-G isoform complexes remain unclear. Here, we use netrin-G-KO and NGL-KO mice to reveal that netrin-G1/NGL1 and netrin-G2/NGL2 interactions specify excitatory synapses in independent hippocampal pathways. In the hippocampal CA1 area, netrin-G1/NGL1 and netrin-G2/NGL2 were expressed in the temporoammonic and Schaffer collateral pathways, respectively. The lack of presynaptic netrin-Gs led to the dispersion of NGLs from postsynaptic membranes. In accord, netrin-G mutant synapses displayed opposing phenotypes in long-term and short-term plasticity through discrete biochemical pathways. The plasticity phenotypes in netrin-G-KOs were phenocopied in NGL-KOs, with a corresponding loss of netrin-Gs from presynaptic membranes. Our findings show that netrin-G/NGL interactions differentially control synaptic plasticity in distinct circuits via retrograde signaling mechanisms and explain how synaptic inputs are diversified to control neuronal activity."}],"publist_id":"5054","doi":"10.1523/JNEUROSCI.1141-14.2014","status":"public","pmid":1,"publication_identifier":{"issn":["0270-6474"],"eissn":["1529-2401"]},"language":[{"iso":"eng"}],"intvolume":"        34","article_type":"original","page":"15779 - 15792","publisher":"Society for Neuroscience","department":[{"_id":"RySh"}],"file":[{"relation":"main_file","checksum":"6913e9bc26e9fc1c0441a739a4199229","creator":"dernst","access_level":"open_access","success":1,"date_created":"2022-05-24T08:41:41Z","file_id":"11410","file_name":"2014_JournNeuroscience_Matsukawa.pdf","file_size":3963728,"content_type":"application/pdf","date_updated":"2022-05-24T08:41:41Z"}],"oa_version":"Published Version","date_updated":"2022-05-24T08:54:54Z","oa":1,"author":[{"last_name":"Matsukawa","first_name":"Hiroshi","full_name":"Matsukawa, Hiroshi"},{"full_name":"Akiyoshi Nishimura, Sachiko","first_name":"Sachiko","last_name":"Akiyoshi Nishimura"},{"first_name":"Qi","full_name":"Zhang, Qi","last_name":"Zhang"},{"last_name":"Luján","full_name":"Luján, Rafael","first_name":"Rafael"},{"last_name":"Yamaguchi","first_name":"Kazuhiko","full_name":"Yamaguchi, Kazuhiko"},{"last_name":"Goto","first_name":"Hiromichi","full_name":"Goto, Hiromichi"},{"full_name":"Yaguchi, Kunio","first_name":"Kunio","last_name":"Yaguchi"},{"first_name":"Tsutomu","full_name":"Hashikawa, Tsutomu","last_name":"Hashikawa"},{"full_name":"Sano, Chie","first_name":"Chie","last_name":"Sano"},{"orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Shigemoto, Ryuichi","first_name":"Ryuichi","last_name":"Shigemoto"},{"full_name":"Nakashiba, Toshiaki","first_name":"Toshiaki","last_name":"Nakashiba"},{"first_name":"Shigeyoshi","full_name":"Itohara, Shigeyoshi","last_name":"Itohara"}],"citation":{"ista":"Matsukawa H, Akiyoshi Nishimura S, Zhang Q, Luján R, Yamaguchi K, Goto H, Yaguchi K, Hashikawa T, Sano C, Shigemoto R, Nakashiba T, Itohara S. 2014. Netrin-G/NGL complexes encode functional synaptic diversification. Journal of Neuroscience. 34(47), 15779–15792.","mla":"Matsukawa, Hiroshi, et al. “Netrin-G/NGL Complexes Encode Functional Synaptic Diversification.” <i>Journal of Neuroscience</i>, vol. 34, no. 47, Society for Neuroscience, 2014, pp. 15779–92, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.1141-14.2014\">10.1523/JNEUROSCI.1141-14.2014</a>.","apa":"Matsukawa, H., Akiyoshi Nishimura, S., Zhang, Q., Luján, R., Yamaguchi, K., Goto, H., … Itohara, S. (2014). Netrin-G/NGL complexes encode functional synaptic diversification. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.1141-14.2014\">https://doi.org/10.1523/JNEUROSCI.1141-14.2014</a>","ieee":"H. Matsukawa <i>et al.</i>, “Netrin-G/NGL complexes encode functional synaptic diversification,” <i>Journal of Neuroscience</i>, vol. 34, no. 47. Society for Neuroscience, pp. 15779–15792, 2014.","short":"H. Matsukawa, S. Akiyoshi Nishimura, Q. Zhang, R. Luján, K. Yamaguchi, H. Goto, K. Yaguchi, T. Hashikawa, C. Sano, R. Shigemoto, T. Nakashiba, S. Itohara, Journal of Neuroscience 34 (2014) 15779–15792.","ama":"Matsukawa H, Akiyoshi Nishimura S, Zhang Q, et al. Netrin-G/NGL complexes encode functional synaptic diversification. <i>Journal of Neuroscience</i>. 2014;34(47):15779-15792. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.1141-14.2014\">10.1523/JNEUROSCI.1141-14.2014</a>","chicago":"Matsukawa, Hiroshi, Sachiko Akiyoshi Nishimura, Qi Zhang, Rafael Luján, Kazuhiko Yamaguchi, Hiromichi Goto, Kunio Yaguchi, et al. “Netrin-G/NGL Complexes Encode Functional Synaptic Diversification.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2014. <a href=\"https://doi.org/10.1523/JNEUROSCI.1141-14.2014\">https://doi.org/10.1523/JNEUROSCI.1141-14.2014</a>."},"has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","external_id":{"pmid":["25411505"]},"scopus_import":"1","file_date_updated":"2022-05-24T08:41:41Z","_id":"2018","year":"2014","volume":34,"article_processing_charge":"No","publication":"Journal of Neuroscience","date_created":"2018-12-11T11:55:14Z","ddc":["570"],"date_published":"2014-11-19T00:00:00Z","title":"Netrin-G/NGL complexes encode functional synaptic diversification","quality_controlled":"1"},{"quality_controlled":"1","date_published":"2014-12-17T00:00:00Z","title":"Phase transition in the density of states of quantum spin glasses","project":[{"_id":"258DCDE6-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"Random matrices, universality and disordered quantum systems","grant_number":"338804"}],"volume":17,"publication":"Mathematical Physics, Analysis and Geometry","year":"2014","main_file_link":[{"url":"http://arxiv.org/abs/1407.1552","open_access":"1"}],"date_created":"2018-12-11T11:55:15Z","scopus_import":1,"_id":"2019","author":[{"orcid":"0000-0001-5366-9603","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","full_name":"Erdös, László","first_name":"László","last_name":"Erdös"},{"first_name":"Dominik J","full_name":"Schröder, Dominik J","last_name":"Schröder"}],"oa":1,"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Erdös L, Schröder DJ. 2014. Phase transition in the density of states of quantum spin glasses. Mathematical Physics, Analysis and Geometry. 17(3–4), 441–464.","mla":"Erdös, László, and Dominik J. Schröder. “Phase Transition in the Density of States of Quantum Spin Glasses.” <i>Mathematical Physics, Analysis and Geometry</i>, vol. 17, no. 3–4, Springer, 2014, pp. 441–64, doi:<a href=\"https://doi.org/10.1007/s11040-014-9164-3\">10.1007/s11040-014-9164-3</a>.","apa":"Erdös, L., &#38; Schröder, D. J. (2014). Phase transition in the density of states of quantum spin glasses. <i>Mathematical Physics, Analysis and Geometry</i>. Springer. <a href=\"https://doi.org/10.1007/s11040-014-9164-3\">https://doi.org/10.1007/s11040-014-9164-3</a>","ieee":"L. Erdös and D. J. Schröder, “Phase transition in the density of states of quantum spin glasses,” <i>Mathematical Physics, Analysis and Geometry</i>, vol. 17, no. 3–4. Springer, pp. 441–464, 2014.","short":"L. Erdös, D.J. Schröder, Mathematical Physics, Analysis and Geometry 17 (2014) 441–464.","ama":"Erdös L, Schröder DJ. Phase transition in the density of states of quantum spin glasses. <i>Mathematical Physics, Analysis and Geometry</i>. 2014;17(3-4):441-464. doi:<a href=\"https://doi.org/10.1007/s11040-014-9164-3\">10.1007/s11040-014-9164-3</a>","chicago":"Erdös, László, and Dominik J Schröder. “Phase Transition in the Density of States of Quantum Spin Glasses.” <i>Mathematical Physics, Analysis and Geometry</i>. Springer, 2014. <a href=\"https://doi.org/10.1007/s11040-014-9164-3\">https://doi.org/10.1007/s11040-014-9164-3</a>."},"department":[{"_id":"LaEr"}],"oa_version":"Submitted Version","date_updated":"2021-01-12T06:54:45Z","type":"journal_article","publisher":"Springer","language":[{"iso":"eng"}],"page":"441 - 464","intvolume":"        17","publist_id":"5053","doi":"10.1007/s11040-014-9164-3","abstract":[{"text":"We prove that the empirical density of states of quantum spin glasses on arbitrary graphs converges to a normal distribution as long as the maximal degree is negligible compared with the total number of edges. This extends the recent results of Keating et al. (2014) that were proved for graphs with bounded chromatic number and with symmetric coupling distribution. Furthermore, we generalise the result to arbitrary hypergraphs. We test the optimality of our condition on the maximal degree for p-uniform hypergraphs that correspond to p-spin glass Hamiltonians acting on n distinguishable spin- 1/2 particles. At the critical threshold p = n1/2 we find a sharp classical-quantum phase transition between the normal distribution and the Wigner semicircle law. The former is characteristic to classical systems with commuting variables, while the latter is a signature of noncommutative random matrix theory.","lang":"eng"}],"issue":"3-4","status":"public","ec_funded":1,"day":"17","publication_status":"published","month":"12"},{"quality_controlled":"1","date_published":"2014-10-31T00:00:00Z","title":"Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling","publisher":"American Association for the Advancement of Science","publication":"Science","language":[{"iso":"eng"}],"volume":346,"main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631524/"}],"year":"2014","page":"626 - 629","date_created":"2018-12-11T11:55:15Z","intvolume":"       346","abstract":[{"lang":"eng","text":"Neurotrophins regulate diverse aspects of neuronal development and plasticity, but their precise in vivo functions during neural circuit assembly in the central brain remain unclear. We show that the neurotrophin receptor tropomyosin-related kinase C (TrkC) is required for dendritic growth and branching of mouse cerebellar Purkinje cells. Sparse TrkC knockout reduced dendrite complexity, but global Purkinje cell knockout had no effect. Removal of the TrkC ligand neurotrophin-3 (NT-3) from cerebellar granule cells, which provide major afferent input to developing Purkinje cell dendrites, rescued the dendrite defects caused by sparse TrkC disruption in Purkinje cells. Our data demonstrate that NT-3 from presynaptic neurons (granule cells) is required for TrkC-dependent competitive dendrite morphogenesis in postsynaptic neurons (Purkinje cells)—a previously unknown mechanism of neural circuit development."}],"publist_id":"5051","doi":"10.1126/science.1258996","scopus_import":1,"issue":"6209","status":"public","_id":"2021","citation":{"apa":"William, J., Hippenmeyer, S., &#38; Luo, L. (2014). Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1258996\">https://doi.org/10.1126/science.1258996</a>","mla":"William, Joo, et al. “Dendrite Morphogenesis Depends on Relative Levels of NT-3/TrkC Signaling.” <i>Science</i>, vol. 346, no. 6209, American Association for the Advancement of Science, 2014, pp. 626–29, doi:<a href=\"https://doi.org/10.1126/science.1258996\">10.1126/science.1258996</a>.","ista":"William J, Hippenmeyer S, Luo L. 2014. Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling. Science. 346(6209), 626–629.","chicago":"William, Joo, Simon Hippenmeyer, and Liqun Luo. “Dendrite Morphogenesis Depends on Relative Levels of NT-3/TrkC Signaling.” <i>Science</i>. American Association for the Advancement of Science, 2014. <a href=\"https://doi.org/10.1126/science.1258996\">https://doi.org/10.1126/science.1258996</a>.","ama":"William J, Hippenmeyer S, Luo L. Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling. <i>Science</i>. 2014;346(6209):626-629. doi:<a href=\"https://doi.org/10.1126/science.1258996\">10.1126/science.1258996</a>","short":"J. William, S. Hippenmeyer, L. Luo, Science 346 (2014) 626–629.","ieee":"J. William, S. Hippenmeyer, and L. Luo, “Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling,” <i>Science</i>, vol. 346, no. 6209. American Association for the Advancement of Science, pp. 626–629, 2014."},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","day":"31","author":[{"last_name":"William","full_name":"William, Joo","first_name":"Joo"},{"last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061"},{"full_name":"Luo, Liqun","first_name":"Liqun","last_name":"Luo"}],"oa":1,"oa_version":"Submitted Version","date_updated":"2021-01-12T06:54:47Z","publication_status":"published","department":[{"_id":"SiHi"}],"type":"journal_article","month":"10"},{"publisher":"Cell Press","intvolume":"       159","page":"775 - 788","language":[{"iso":"eng"}],"status":"public","issue":"4","abstract":[{"lang":"eng","text":"Radial glial progenitors (RGPs) are responsible for producing nearly all neocortical neurons. To gain insight into the patterns of RGP division and neuron production, we quantitatively analyzed excitatory neuron genesis in the mouse neocortex using Mosaic Analysis with Double Markers, which provides single-cell resolution of progenitor division patterns and potential in vivo. We found that RGPs progress through a coherent program in which their proliferative potential diminishes in a predictable manner. Upon entry into the neurogenic phase, individual RGPs produce ∼8–9 neurons distributed in both deep and superficial layers, indicating a unitary output in neuronal production. Removal of OTX1, a transcription factor transiently expressed in RGPs, results in both deep- and superficial-layer neuron loss and a reduction in neuronal unit size. Moreover, ∼1/6 of neurogenic RGPs proceed to produce glia. These results suggest that progenitor behavior and histogenesis in the mammalian neocortex conform to a remarkably orderly and deterministic program."}],"doi":"10.1016/j.cell.2014.10.027","publist_id":"5050","month":"11","publication_status":"published","ec_funded":1,"day":"06","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"title":"Deterministic progenitor behavior and unitary production of neurons in the neocortex","date_published":"2014-11-06T00:00:00Z","project":[{"call_identifier":"FP7","_id":"25D61E48-B435-11E9-9278-68D0E5697425","grant_number":"618444","name":"Molecular Mechanisms of Cerebral Cortex Development"},{"_id":"25D7962E-B435-11E9-9278-68D0E5697425","name":"Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal Level","grant_number":"RGP0053/2014"}],"quality_controlled":"1","date_created":"2018-12-11T11:55:16Z","ddc":["570"],"year":"2014","volume":159,"publication":"Cell","_id":"2022","scopus_import":1,"file_date_updated":"2020-07-14T12:45:25Z","pubrep_id":"423","type":"journal_article","department":[{"_id":"SiHi"},{"_id":"Bio"}],"file":[{"access_level":"open_access","file_id":"4709","date_created":"2018-12-12T10:08:47Z","file_name":"IST-2016-423-v1+1_1-s2.0-S0092867414013154-main.pdf","content_type":"application/pdf","date_updated":"2020-07-14T12:45:25Z","file_size":4435787,"checksum":"6c5de8329bb2ffa71cba9fda750f14ce","relation":"main_file","creator":"system"}],"oa_version":"Published Version","date_updated":"2021-01-12T06:54:47Z","oa":1,"author":[{"last_name":"Gao","full_name":"Gao, Peng","first_name":"Peng"},{"first_name":"Maria P","full_name":"Postiglione, Maria P","id":"2C67902A-F248-11E8-B48F-1D18A9856A87","last_name":"Postiglione"},{"last_name":"Krieger","full_name":"Krieger, Teresa","first_name":"Teresa"},{"last_name":"Hernandez","full_name":"Hernandez, Luisirene","first_name":"Luisirene"},{"last_name":"Wang","full_name":"Wang, Chao","first_name":"Chao"},{"last_name":"Han","first_name":"Zhi","full_name":"Han, Zhi"},{"first_name":"Carmen","full_name":"Streicher, Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","last_name":"Streicher"},{"last_name":"Papusheva","full_name":"Papusheva, Ekaterina","id":"41DB591E-F248-11E8-B48F-1D18A9856A87","first_name":"Ekaterina"},{"full_name":"Insolera, Ryan","first_name":"Ryan","last_name":"Insolera"},{"last_name":"Chugh","full_name":"Chugh, Kritika","first_name":"Kritika"},{"last_name":"Kodish","first_name":"Oren","full_name":"Kodish, Oren"},{"last_name":"Huang","first_name":"Kun","full_name":"Huang, Kun"},{"last_name":"Simons","full_name":"Simons, Benjamin","first_name":"Benjamin"},{"full_name":"Luo, Liqun","first_name":"Liqun","last_name":"Luo"},{"last_name":"Hippenmeyer","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","full_name":"Hippenmeyer, Simon"},{"first_name":"Song","full_name":"Shi, Song","last_name":"Shi"}],"citation":{"ieee":"P. Gao <i>et al.</i>, “Deterministic progenitor behavior and unitary production of neurons in the neocortex,” <i>Cell</i>, vol. 159, no. 4. Cell Press, pp. 775–788, 2014.","short":"P. Gao, M.P. Postiglione, T. Krieger, L. Hernandez, C. Wang, Z. Han, C. Streicher, E. Papusheva, R. Insolera, K. Chugh, O. Kodish, K. Huang, B. Simons, L. Luo, S. Hippenmeyer, S. Shi, Cell 159 (2014) 775–788.","ama":"Gao P, Postiglione MP, Krieger T, et al. Deterministic progenitor behavior and unitary production of neurons in the neocortex. <i>Cell</i>. 2014;159(4):775-788. doi:<a href=\"https://doi.org/10.1016/j.cell.2014.10.027\">10.1016/j.cell.2014.10.027</a>","chicago":"Gao, Peng, Maria P Postiglione, Teresa Krieger, Luisirene Hernandez, Chao Wang, Zhi Han, Carmen Streicher, et al. “Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex.” <i>Cell</i>. Cell Press, 2014. <a href=\"https://doi.org/10.1016/j.cell.2014.10.027\">https://doi.org/10.1016/j.cell.2014.10.027</a>.","ista":"Gao P, Postiglione MP, Krieger T, Hernandez L, Wang C, Han Z, Streicher C, Papusheva E, Insolera R, Chugh K, Kodish O, Huang K, Simons B, Luo L, Hippenmeyer S, Shi S. 2014. Deterministic progenitor behavior and unitary production of neurons in the neocortex. Cell. 159(4), 775–788.","apa":"Gao, P., Postiglione, M. P., Krieger, T., Hernandez, L., Wang, C., Han, Z., … Shi, S. (2014). Deterministic progenitor behavior and unitary production of neurons in the neocortex. <i>Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cell.2014.10.027\">https://doi.org/10.1016/j.cell.2014.10.027</a>","mla":"Gao, Peng, et al. “Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex.” <i>Cell</i>, vol. 159, no. 4, Cell Press, 2014, pp. 775–88, doi:<a href=\"https://doi.org/10.1016/j.cell.2014.10.027\">10.1016/j.cell.2014.10.027</a>."},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1"},{"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"title":"Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution","date_published":"2014-11-27T00:00:00Z","project":[{"_id":"25B07788-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"Limits to selection in biology and in evolutionary computation","grant_number":"250152"}],"quality_controlled":"1","date_created":"2018-12-11T11:55:16Z","ddc":["570"],"year":"2014","volume":4,"publication":"Ecology and Evolution","_id":"2023","scopus_import":1,"file_date_updated":"2020-07-14T12:45:25Z","pubrep_id":"462","type":"journal_article","file":[{"content_type":"application/pdf","date_updated":"2020-07-14T12:45:25Z","file_size":118813,"file_name":"IST-2016-462-v1+1_Novak-2014-Ecology_and_Evolution.pdf","file_id":"4946","date_created":"2018-12-12T10:12:28Z","access_level":"open_access","creator":"system","checksum":"9ab43db1b0fede7bfe560ed77e177b76","relation":"main_file"}],"department":[{"_id":"NiBa"}],"date_updated":"2023-09-07T11:55:53Z","oa_version":"Published Version","oa":1,"author":[{"first_name":"Sebastian","id":"461468AE-F248-11E8-B48F-1D18A9856A87","full_name":"Novak, Sebastian","orcid":"0000-0002-2519-824X","last_name":"Novak"}],"citation":{"ista":"Novak S. 2014. Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution. Ecology and Evolution. 4(24), 4589–4597.","mla":"Novak, Sebastian. “Habitat Heterogeneities versus Spatial Type Frequency Variances as Driving Forces of Dispersal Evolution.” <i>Ecology and Evolution</i>, vol. 4, no. 24, Wiley-Blackwell, 2014, pp. 4589–97, doi:<a href=\"https://doi.org/10.1002/ece3.1289\">10.1002/ece3.1289</a>.","apa":"Novak, S. (2014). Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution. <i>Ecology and Evolution</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/ece3.1289\">https://doi.org/10.1002/ece3.1289</a>","ieee":"S. Novak, “Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution,” <i>Ecology and Evolution</i>, vol. 4, no. 24. Wiley-Blackwell, pp. 4589–4597, 2014.","ama":"Novak S. Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution. <i>Ecology and Evolution</i>. 2014;4(24):4589-4597. doi:<a href=\"https://doi.org/10.1002/ece3.1289\">10.1002/ece3.1289</a>","short":"S. Novak, Ecology and Evolution 4 (2014) 4589–4597.","chicago":"Novak, Sebastian. “Habitat Heterogeneities versus Spatial Type Frequency Variances as Driving Forces of Dispersal Evolution.” <i>Ecology and Evolution</i>. Wiley-Blackwell, 2014. <a href=\"https://doi.org/10.1002/ece3.1289\">https://doi.org/10.1002/ece3.1289</a>."},"has_accepted_license":"1","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","publisher":"Wiley-Blackwell","intvolume":"         4","page":"4589 - 4597","language":[{"iso":"eng"}],"status":"public","issue":"24","publist_id":"5049","abstract":[{"lang":"eng","text":"Understanding the evolution of dispersal is essential for understanding and predicting the dynamics of natural populations. Two main factors are known to influence dispersal evolution: spatio-temporal variation in the environment and relatedness between individuals. However, the relation between these factors is still poorly understood, and they are usually treated separately. In this article, I present a theoretical framework that contains and connects effects of both environmental variation and relatedness, and reproduces and extends their known features. Spatial habitat variation selects for balanced dispersal strategies, whereby the population is kept at an ideal free distribution. Within this class of dispersal strategies, I explain how increased dispersal is promoted by perturbations to the dispersal type frequencies. An explicit formula shows the magnitude of the selective advantage of increased dispersal in terms of the spatial variability in the frequencies of the different dispersal strategies present. These variances are capable of capturing various sources of stochasticity and hence establish a common scale for their effects on the evolution of dispersal. The results furthermore indicate an alternative approach to identifying effects of relatedness on dispersal evolution."}],"doi":"10.1002/ece3.1289","related_material":{"record":[{"id":"1125","relation":"dissertation_contains","status":"public"}]},"month":"11","publication_status":"published","ec_funded":1,"day":"27"}]