[{"oa":1,"external_id":{"arxiv":["1506.08547"]},"day":"15","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1506.08547v7"}],"article_number":"7782993","doi":"10.1109/FOCS.2016.88","date_published":"2016-12-15T00:00:00Z","related_material":{"record":[{"status":"public","id":"5975","relation":"later_version"}]},"status":"public","month":"12","arxiv":1,"acknowledgement":"European Unions Seventh Framework Programme (FP7/2007-2013)/ERC grant agreement no 616160","quality_controlled":"1","type":"conference","citation":{"ama":"Kolmogorov V. Commutativity in the algorithmic Lovasz local lemma. In: <i>Proceedings - Annual IEEE Symposium on Foundations of Computer Science</i>. Vol 2016-December. IEEE; 2016. doi:<a href=\"https://doi.org/10.1109/FOCS.2016.88\">10.1109/FOCS.2016.88</a>","mla":"Kolmogorov, Vladimir. “Commutativity in the Algorithmic Lovasz Local Lemma.” <i>Proceedings - Annual IEEE Symposium on Foundations of Computer Science</i>, vol. 2016–December, 7782993, IEEE, 2016, doi:<a href=\"https://doi.org/10.1109/FOCS.2016.88\">10.1109/FOCS.2016.88</a>.","apa":"Kolmogorov, V. (2016). Commutativity in the algorithmic Lovasz local lemma. In <i>Proceedings - Annual IEEE Symposium on Foundations of Computer Science</i> (Vol. 2016–December). New Brunswick, NJ, USA : IEEE. <a href=\"https://doi.org/10.1109/FOCS.2016.88\">https://doi.org/10.1109/FOCS.2016.88</a>","short":"V. Kolmogorov, in:, Proceedings - Annual IEEE Symposium on Foundations of Computer Science, IEEE, 2016.","ieee":"V. Kolmogorov, “Commutativity in the algorithmic Lovasz local lemma,” in <i>Proceedings - Annual IEEE Symposium on Foundations of Computer Science</i>, New Brunswick, NJ, USA , 2016, vol. 2016–December.","ista":"Kolmogorov V. 2016. Commutativity in the algorithmic Lovasz local lemma. Proceedings - Annual IEEE Symposium on Foundations of Computer Science. FOCS: Foundations of Computer Science vol. 2016–December, 7782993.","chicago":"Kolmogorov, Vladimir. “Commutativity in the Algorithmic Lovasz Local Lemma.” In <i>Proceedings - Annual IEEE Symposium on Foundations of Computer Science</i>, Vol. 2016–December. IEEE, 2016. <a href=\"https://doi.org/10.1109/FOCS.2016.88\">https://doi.org/10.1109/FOCS.2016.88</a>."},"oa_version":"Preprint","date_created":"2018-12-11T11:50:38Z","publication":"Proceedings - Annual IEEE Symposium on Foundations of Computer Science","title":"Commutativity in the algorithmic Lovasz local lemma","project":[{"name":"Discrete Optimization in Computer Vision: Theory and Practice","call_identifier":"FP7","_id":"25FBA906-B435-11E9-9278-68D0E5697425","grant_number":"616160"}],"department":[{"_id":"VlKo"}],"ec_funded":1,"_id":"1193","publisher":"IEEE","publist_id":"6158","publication_status":"published","conference":{"end_date":"2016-09-11","location":"New Brunswick, NJ, USA ","name":"FOCS: Foundations of Computer Science","start_date":"2016-09-09"},"author":[{"first_name":"Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","last_name":"Kolmogorov","full_name":"Kolmogorov, Vladimir"}],"language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"We consider the recent formulation of the Algorithmic Lovász Local Lemma [1], [2] for finding objects that avoid &quot;bad features&quot;, or &quot;flaws&quot;. It extends the Moser-Tardos resampling algorithm [3] to more general discrete spaces. At each step the method picks a flaw present in the current state and &quot;resamples&quot; it using a &quot;resampling oracle&quot; provided by the user. However, it is less flexible than the Moser-Tardos method since [1], [2] require a specific flaw selection rule, whereas [3] allows an arbitrary rule (and thus can potentially be implemented more efficiently). We formulate a new &quot;commutativity&quot; condition, and prove that it is sufficient for an arbitrary rule to work. It also enables an efficient parallelization under an additional assumption. We then show that existing resampling oracles for perfect matchings and permutations do satisfy this condition. Finally, we generalize the precondition in [2] (in the case of symmetric potential causality graphs). This unifies special cases that previously were treated separately."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","date_updated":"2023-09-19T14:24:57Z","volume":"2016-December","scopus_import":1,"year":"2016"},{"day":"03","oa":1,"status":"public","doi":"10.1093/molbev/msw210","date_published":"2016-10-03T00:00:00Z","intvolume":"        34","quality_controlled":"1","acknowledgement":"The authors thank all members of the Institute of Population\r\nGenetics for discussion and support on the project and par-\r\nticularly N. Barghi for helpful comments on earlier versions of\r\nthe  manuscript.  This  work  was  supported  by  the  European\r\nResearch Council (ERC) grants “ArchAdapt” and “250152”.","pubrep_id":"770","month":"10","publication":"Molecular Biology and Evolution","oa_version":"Submitted Version","citation":{"ama":"Franssen S, Barton NH, Schlötterer C. Reconstruction of haplotype-blocks selected during experimental evolution. <i>Molecular Biology and Evolution</i>. 2016;34(1):174-184. doi:<a href=\"https://doi.org/10.1093/molbev/msw210\">10.1093/molbev/msw210</a>","apa":"Franssen, S., Barton, N. H., &#38; Schlötterer, C. (2016). Reconstruction of haplotype-blocks selected during experimental evolution. <i>Molecular Biology and Evolution</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/molbev/msw210\">https://doi.org/10.1093/molbev/msw210</a>","mla":"Franssen, Susan, et al. “Reconstruction of Haplotype-Blocks Selected during Experimental Evolution.” <i>Molecular Biology and Evolution</i>, vol. 34, no. 1, Oxford University Press, 2016, pp. 174–84, doi:<a href=\"https://doi.org/10.1093/molbev/msw210\">10.1093/molbev/msw210</a>.","ieee":"S. Franssen, N. H. Barton, and C. Schlötterer, “Reconstruction of haplotype-blocks selected during experimental evolution.,” <i>Molecular Biology and Evolution</i>, vol. 34, no. 1. Oxford University Press, pp. 174–184, 2016.","short":"S. Franssen, N.H. Barton, C. Schlötterer, Molecular Biology and Evolution 34 (2016) 174–184.","chicago":"Franssen, Susan, Nicholas H Barton, and Christian Schlötterer. “Reconstruction of Haplotype-Blocks Selected during Experimental Evolution.” <i>Molecular Biology and Evolution</i>. Oxford University Press, 2016. <a href=\"https://doi.org/10.1093/molbev/msw210\">https://doi.org/10.1093/molbev/msw210</a>.","ista":"Franssen S, Barton NH, Schlötterer C. 2016. Reconstruction of haplotype-blocks selected during experimental evolution. Molecular Biology and Evolution. 34(1), 174–184."},"date_created":"2018-12-11T11:50:39Z","type":"journal_article","department":[{"_id":"NiBa"}],"project":[{"name":"Limits to selection in biology and in evolutionary computation","call_identifier":"FP7","_id":"25B07788-B435-11E9-9278-68D0E5697425","grant_number":"250152"}],"page":"174 - 184","title":"Reconstruction of haplotype-blocks selected during experimental evolution.","publication_status":"published","ddc":["576"],"file_date_updated":"2020-07-14T12:44:38Z","publisher":"Oxford University Press","publist_id":"6155","ec_funded":1,"_id":"1195","file":[{"file_size":295274,"date_created":"2018-12-12T10:16:35Z","file_id":"5223","relation":"main_file","content_type":"application/pdf","access_level":"open_access","creator":"system","checksum":"1e78d3aaffcb40dc8b02b7b4666019e0","file_name":"IST-2017-770-v1+1_FranssenEtAl_nofigs-1.pdf","date_updated":"2020-07-14T12:44:38Z"},{"checksum":"e13171843283774404c936c581b4543e","file_name":"IST-2017-770-v1+2_Fig1.pdf","date_updated":"2020-07-14T12:44:38Z","file_size":10902625,"date_created":"2018-12-12T10:16:36Z","file_id":"5224","relation":"main_file","content_type":"application/pdf","access_level":"open_access","creator":"system"},{"access_level":"open_access","content_type":"application/pdf","creator":"system","file_id":"5225","relation":"main_file","file_size":21437,"date_created":"2018-12-12T10:16:37Z","file_name":"IST-2017-770-v1+3_Fig2.pdf","date_updated":"2020-07-14T12:44:38Z","checksum":"63bc6e6e61f347594d8c00c37f874a0b"},{"checksum":"da87cc7c78808837f22a3dae1c8397f9","date_updated":"2020-07-14T12:44:38Z","file_name":"IST-2017-770-v1+4_Fig3.pdf","relation":"main_file","file_id":"5226","creator":"system","content_type":"application/pdf","access_level":"open_access","date_created":"2018-12-12T10:16:38Z","file_size":1172194},{"checksum":"e47b2a0c32142f423b3100150c0294f8","file_name":"IST-2017-770-v1+5_Fig4.pdf","date_updated":"2020-07-14T12:44:38Z","file_id":"5227","relation":"main_file","content_type":"application/pdf","access_level":"open_access","creator":"system","file_size":50045,"date_created":"2018-12-12T10:16:38Z"},{"checksum":"a5a7d6b32e7e17d35d337d7ec2a9f6c9","date_updated":"2020-07-14T12:44:38Z","file_name":"IST-2017-770-v1+6_Fig5.pdf","date_created":"2018-12-12T10:16:39Z","file_size":50705,"relation":"main_file","file_id":"5228","creator":"system","content_type":"application/pdf","access_level":"open_access"}],"date_updated":"2021-01-12T06:49:00Z","abstract":[{"text":"The genetic analysis of experimentally evolving populations typically relies on short reads from pooled individuals (Pool-Seq). While this method provides reliable allele frequency estimates, the underlying haplotype structure remains poorly characterized. With small population sizes and adaptive variants that start from low frequencies, the interpretation of selection signatures in most Evolve and Resequencing studies remains challenging. To facilitate the characterization of selection targets, we propose a new approach that reconstructs selected haplotypes from replicated time series, using Pool-Seq data. We identify selected haplotypes through the correlated frequencies of alleles carried by them. Computer simulations indicate that selected haplotype-blocks of several Mb can be reconstructed with high confidence and low error rates, even when allele frequencies change only by 20% across three replicates. Applying this method to real data from D. melanogaster populations adapting to a hot environment, we identify a selected haplotype-block of 6.93 Mb. We confirm the presence of this haplotype-block in evolved populations by experimental haplotyping, demonstrating the power and accuracy of our haplotype reconstruction from Pool-Seq data. We propose that the combination of allele frequency estimates with haplotype information will provide the key to understanding the dynamics of adaptive alleles. ","lang":"eng"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"author":[{"first_name":"Susan","last_name":"Franssen","full_name":"Franssen, Susan"},{"last_name":"Barton","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","orcid":"0000-0002-8548-5240"},{"last_name":"Schlötterer","full_name":"Schlötterer, Christian","first_name":"Christian"}],"scopus_import":1,"issue":"1","year":"2016","volume":34,"has_accepted_license":"1"},{"day":"17","oa":1,"status":"public","related_material":{"record":[{"status":"public","id":"9709","relation":"research_data"}]},"date_published":"2016-11-17T00:00:00Z","doi":"10.1371/journal.pcbi.1005148","intvolume":"        12","article_number":"e1005855","quality_controlled":"1","license":"https://creativecommons.org/licenses/by/4.0/","acknowledgement":"JSP was supported by a C.V. Starr Fellowship from the Starr Foundation (http://www.starrfoundation.org/). GT was supported by Austrian Research Foundation (https://www.fwf.ac.at/en/) grant FWF P25651. MJB received support from National Eye Institute (https://nei.nih.gov/) grant EY 14196 and from the National Science Foundation grant 1504977. The authors thank Cristina Savin and Vicent Botella-Soler for helpful comments on the manuscript.","month":"11","publication":"PLoS Computational Biology","citation":{"ama":"Prentice J, Marre O, Ioffe M, Loback A, Tkačik G, Berry M. Error-robust modes of the retinal population code. <i>PLoS Computational Biology</i>. 2016;12(11). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1005148\">10.1371/journal.pcbi.1005148</a>","mla":"Prentice, Jason, et al. “Error-Robust Modes of the Retinal Population Code.” <i>PLoS Computational Biology</i>, vol. 12, no. 11, e1005855, Public Library of Science, 2016, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1005148\">10.1371/journal.pcbi.1005148</a>.","apa":"Prentice, J., Marre, O., Ioffe, M., Loback, A., Tkačik, G., &#38; Berry, M. (2016). Error-robust modes of the retinal population code. <i>PLoS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1005148\">https://doi.org/10.1371/journal.pcbi.1005148</a>","short":"J. Prentice, O. Marre, M. Ioffe, A. Loback, G. Tkačik, M. Berry, PLoS Computational Biology 12 (2016).","ieee":"J. Prentice, O. Marre, M. Ioffe, A. Loback, G. Tkačik, and M. Berry, “Error-robust modes of the retinal population code,” <i>PLoS Computational Biology</i>, vol. 12, no. 11. Public Library of Science, 2016.","ista":"Prentice J, Marre O, Ioffe M, Loback A, Tkačik G, Berry M. 2016. Error-robust modes of the retinal population code. PLoS Computational Biology. 12(11), e1005855.","chicago":"Prentice, Jason, Olivier Marre, Mark Ioffe, Adrianna Loback, Gašper Tkačik, and Michael Berry. “Error-Robust Modes of the Retinal Population Code.” <i>PLoS Computational Biology</i>. Public Library of Science, 2016. <a href=\"https://doi.org/10.1371/journal.pcbi.1005148\">https://doi.org/10.1371/journal.pcbi.1005148</a>."},"oa_version":"Published Version","date_created":"2018-12-11T11:50:40Z","type":"journal_article","department":[{"_id":"GaTk"}],"project":[{"call_identifier":"FWF","name":"Sensitivity to higher-order statistics in natural scenes","_id":"254D1A94-B435-11E9-9278-68D0E5697425","grant_number":"P 25651-N26"}],"title":"Error-robust modes of the retinal population code","publication_status":"published","file_date_updated":"2020-07-14T12:44:38Z","ddc":["570"],"publisher":"Public Library of Science","publist_id":"6153","_id":"1197","file":[{"checksum":"47b08cbd4dbf32b25ba161f5f4b262cc","file_name":"2016_PLOS_Prentice.pdf","date_updated":"2020-07-14T12:44:38Z","file_id":"5884","relation":"main_file","access_level":"open_access","content_type":"application/pdf","creator":"kschuh","file_size":4492021,"date_created":"2019-01-25T10:35:00Z"}],"date_updated":"2023-02-23T14:05:40Z","abstract":[{"text":"Across the nervous system, certain population spiking patterns are observed far more frequently than others. A hypothesis about this structure is that these collective activity patterns function as population codewords–collective modes–carrying information distinct from that of any single cell. We investigate this phenomenon in recordings of ∼150 retinal ganglion cells, the retina’s output. We develop a novel statistical model that decomposes the population response into modes; it predicts the distribution of spiking activity in the ganglion cell population with high accuracy. We found that the modes represent localized features of the visual stimulus that are distinct from the features represented by single neurons. Modes form clusters of activity states that are readily discriminated from one another. When we repeated the same visual stimulus, we found that the same mode was robustly elicited. These results suggest that retinal ganglion cells’ collective signaling is endowed with a form of error-correcting code–a principle that may hold in brain areas beyond retina.","lang":"eng"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"author":[{"first_name":"Jason","full_name":"Prentice, Jason","last_name":"Prentice"},{"last_name":"Marre","full_name":"Marre, Olivier","first_name":"Olivier"},{"first_name":"Mark","last_name":"Ioffe","full_name":"Ioffe, Mark"},{"full_name":"Loback, Adrianna","last_name":"Loback","first_name":"Adrianna"},{"first_name":"Gasper","full_name":"Tkacik, Gasper","last_name":"Tkacik","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6699-1455"},{"first_name":"Michael","full_name":"Berry, Michael","last_name":"Berry"}],"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"scopus_import":1,"issue":"11","year":"2016","volume":12,"has_accepted_license":"1"},{"oa":1,"day":"01","status":"public","date_published":"2016-12-01T00:00:00Z","doi":"10.1016/j.plrev.2016.10.004","intvolume":"        19","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","acknowledgement":"C.H. acknowledges generous support from the ISTFELLOW program.","quality_controlled":"1","pubrep_id":"798","month":"12","oa_version":"Submitted Version","citation":{"mla":"Hilbe, Christian, and Arne Traulsen. “Only the Combination of Mathematics and Agent Based Simulations Can Leverage the Full Potential of Evolutionary Modeling: Comment on ‘Evolutionary Game Theory Using Agent-Based Methods’ by C. Adami, J. Schossau and A. Hintze.” <i>Physics of Life Reviews</i>, vol. 19, Elsevier, 2016, pp. 29–31, doi:<a href=\"https://doi.org/10.1016/j.plrev.2016.10.004\">10.1016/j.plrev.2016.10.004</a>.","apa":"Hilbe, C., &#38; Traulsen, A. (2016). Only the combination of mathematics and agent based simulations can leverage the full potential of evolutionary modeling: Comment on “Evolutionary game theory using agent-based methods” by C. Adami, J. Schossau and A. Hintze. <i>Physics of Life Reviews</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.plrev.2016.10.004\">https://doi.org/10.1016/j.plrev.2016.10.004</a>","ama":"Hilbe C, Traulsen A. Only the combination of mathematics and agent based simulations can leverage the full potential of evolutionary modeling: Comment on “Evolutionary game theory using agent-based methods” by C. Adami, J. Schossau and A. Hintze. <i>Physics of Life Reviews</i>. 2016;19:29-31. doi:<a href=\"https://doi.org/10.1016/j.plrev.2016.10.004\">10.1016/j.plrev.2016.10.004</a>","ista":"Hilbe C, Traulsen A. 2016. Only the combination of mathematics and agent based simulations can leverage the full potential of evolutionary modeling: Comment on “Evolutionary game theory using agent-based methods” by C. Adami, J. Schossau and A. Hintze. Physics of Life Reviews. 19, 29–31.","chicago":"Hilbe, Christian, and Arne Traulsen. “Only the Combination of Mathematics and Agent Based Simulations Can Leverage the Full Potential of Evolutionary Modeling: Comment on ‘Evolutionary Game Theory Using Agent-Based Methods’ by C. Adami, J. Schossau and A. Hintze.” <i>Physics of Life Reviews</i>. Elsevier, 2016. <a href=\"https://doi.org/10.1016/j.plrev.2016.10.004\">https://doi.org/10.1016/j.plrev.2016.10.004</a>.","ieee":"C. Hilbe and A. Traulsen, “Only the combination of mathematics and agent based simulations can leverage the full potential of evolutionary modeling: Comment on ‘Evolutionary game theory using agent-based methods’ by C. Adami, J. Schossau and A. Hintze,” <i>Physics of Life Reviews</i>, vol. 19. Elsevier, pp. 29–31, 2016.","short":"C. Hilbe, A. Traulsen, Physics of Life Reviews 19 (2016) 29–31."},"date_created":"2018-12-11T11:50:40Z","publication":"Physics of Life Reviews","type":"journal_article","department":[{"_id":"KrCh"}],"page":"29 - 31","title":"Only the combination of mathematics and agent based simulations can leverage the full potential of evolutionary modeling: Comment on “Evolutionary game theory using agent-based methods” by C. Adami, J. Schossau and A. Hintze","project":[{"call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734"}],"ddc":["530"],"publication_status":"published","file_date_updated":"2020-07-14T12:44:39Z","ec_funded":1,"_id":"1200","publisher":"Elsevier","publist_id":"6150","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T06:49:03Z","file":[{"file_name":"IST-2017-798-v1+1_comment_adami.pdf","date_updated":"2020-07-14T12:44:39Z","checksum":"95e6dc78278334b99dacbf8822509364","file_size":171352,"date_created":"2018-12-12T10:11:02Z","access_level":"open_access","content_type":"application/pdf","creator":"system","file_id":"4855","relation":"main_file"}],"author":[{"first_name":"Christian","id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87","full_name":"Hilbe, Christian","last_name":"Hilbe","orcid":"0000-0001-5116-955X"},{"full_name":"Traulsen, Arne","last_name":"Traulsen","first_name":"Arne"}],"language":[{"iso":"eng"}],"scopus_import":1,"tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"year":"2016","has_accepted_license":"1","volume":19},{"quality_controlled":"1","acknowledgement":"The authors thank Sophie A.O. Armitage and Jan N. Offenborn for helpful comments on the figures, and two anonymous reviewers for their helpful comments. The project was funded by the Deutsche Forschungsgemeinschaft (DFG, KU 1929/4-2) within the priority programme SPP 1399 “Host–Parasite Coevolution”.","month":"08","publication":"Zoology ","date_created":"2018-12-11T11:50:41Z","citation":{"ama":"Milutinovic B, Peuß R, Ferro K, Kurtz J. Immune priming in arthropods: an update focusing on the red flour beetle. <i>Zoology </i>. 2016;119(4):254-261. doi:<a href=\"https://doi.org/10.1016/j.zool.2016.03.006\">10.1016/j.zool.2016.03.006</a>","mla":"Milutinovic, Barbara, et al. “Immune Priming in Arthropods: An Update Focusing on the Red Flour Beetle.” <i>Zoology </i>, vol. 119, no. 4, Elsevier, 2016, pp. 254–61, doi:<a href=\"https://doi.org/10.1016/j.zool.2016.03.006\">10.1016/j.zool.2016.03.006</a>.","apa":"Milutinovic, B., Peuß, R., Ferro, K., &#38; Kurtz, J. (2016). Immune priming in arthropods: an update focusing on the red flour beetle. <i>Zoology </i>. Elsevier. <a href=\"https://doi.org/10.1016/j.zool.2016.03.006\">https://doi.org/10.1016/j.zool.2016.03.006</a>","short":"B. Milutinovic, R. Peuß, K. Ferro, J. Kurtz, Zoology  119 (2016) 254–261.","ieee":"B. Milutinovic, R. Peuß, K. Ferro, and J. Kurtz, “Immune priming in arthropods: an update focusing on the red flour beetle,” <i>Zoology </i>, vol. 119, no. 4. Elsevier, pp. 254–261, 2016.","chicago":"Milutinovic, Barbara, Robert Peuß, Kevin Ferro, and Joachim Kurtz. “Immune Priming in Arthropods: An Update Focusing on the Red Flour Beetle.” <i>Zoology </i>. Elsevier, 2016. <a href=\"https://doi.org/10.1016/j.zool.2016.03.006\">https://doi.org/10.1016/j.zool.2016.03.006</a>.","ista":"Milutinovic B, Peuß R, Ferro K, Kurtz J. 2016. Immune priming in arthropods: an update focusing on the red flour beetle. Zoology . 119(4), 254–261."},"oa_version":"Published Version","type":"journal_article","day":"01","oa":1,"status":"public","intvolume":"       119","doi":"10.1016/j.zool.2016.03.006","date_published":"2016-08-01T00:00:00Z","date_updated":"2021-01-12T06:49:03Z","file":[{"date_created":"2019-01-25T13:00:20Z","file_size":1473211,"relation":"main_file","file_id":"5885","creator":"kschuh","content_type":"application/pdf","access_level":"open_access","checksum":"8396d5bd95f9c4295857162f902afabf","date_updated":"2020-07-14T12:44:39Z","file_name":"2016_Elsevier_Milutinovic.pdf"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-8214-4758","first_name":"Barbara","id":"2CDC32B8-F248-11E8-B48F-1D18A9856A87","full_name":"Milutinovic, Barbara","last_name":"Milutinovic"},{"last_name":"Peuß","full_name":"Peuß, Robert","first_name":"Robert"},{"last_name":"Ferro","full_name":"Ferro, Kevin","first_name":"Kevin"},{"full_name":"Kurtz, Joachim","last_name":"Kurtz","first_name":"Joachim"}],"year":"2016","issue":"4","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"scopus_import":1,"volume":119,"has_accepted_license":"1","department":[{"_id":"SyCr"}],"project":[{"_id":"25DAF0B2-B435-11E9-9278-68D0E5697425","name":"Host-Parasite Coevolution","grant_number":"CR-118/3-1"}],"page":"254 - 261","title":"Immune priming in arthropods: an update focusing on the red flour beetle","file_date_updated":"2020-07-14T12:44:39Z","publication_status":"published","ddc":["570"],"publist_id":"6147","publisher":"Elsevier","_id":"1202"},{"publication":"Journal of Clinical Microbiology","date_created":"2018-12-11T11:50:41Z","oa_version":"Submitted Version","citation":{"apa":"Hu, F., Rishishwar, L., Sivadas, A., Mitchell, G., King, J., Murphy, T., … Wang, X. (2016). Comparative genomic analysis of Haemophilus haemolyticus and nontypeable Haemophilus influenzae and a new testing scheme for their discrimination. <i>Journal of Clinical Microbiology</i>. American Society for Microbiology. <a href=\"https://doi.org/10.1128/JCM.01511-16\">https://doi.org/10.1128/JCM.01511-16</a>","mla":"Hu, Fang, et al. “Comparative Genomic Analysis of Haemophilus Haemolyticus and Nontypeable Haemophilus Influenzae and a New Testing Scheme for Their Discrimination.” <i>Journal of Clinical Microbiology</i>, vol. 54, no. 12, American Society for Microbiology, 2016, pp. 3010–17, doi:<a href=\"https://doi.org/10.1128/JCM.01511-16\">10.1128/JCM.01511-16</a>.","ama":"Hu F, Rishishwar L, Sivadas A, et al. Comparative genomic analysis of Haemophilus haemolyticus and nontypeable Haemophilus influenzae and a new testing scheme for their discrimination. <i>Journal of Clinical Microbiology</i>. 2016;54(12):3010-3017. doi:<a href=\"https://doi.org/10.1128/JCM.01511-16\">10.1128/JCM.01511-16</a>","ista":"Hu F, Rishishwar L, Sivadas A, Mitchell G, King J, Murphy T, Gilsdorf J, Mayer L, Wang X. 2016. Comparative genomic analysis of Haemophilus haemolyticus and nontypeable Haemophilus influenzae and a new testing scheme for their discrimination. Journal of Clinical Microbiology. 54(12), 3010–3017.","chicago":"Hu, Fang, Lavanya Rishishwar, Ambily Sivadas, Gabriel Mitchell, Jordan King, Timothy Murphy, Janet Gilsdorf, Leonard Mayer, and Xin Wang. “Comparative Genomic Analysis of Haemophilus Haemolyticus and Nontypeable Haemophilus Influenzae and a New Testing Scheme for Their Discrimination.” <i>Journal of Clinical Microbiology</i>. American Society for Microbiology, 2016. <a href=\"https://doi.org/10.1128/JCM.01511-16\">https://doi.org/10.1128/JCM.01511-16</a>.","short":"F. Hu, L. Rishishwar, A. Sivadas, G. Mitchell, J. King, T. Murphy, J. Gilsdorf, L. Mayer, X. Wang, Journal of Clinical Microbiology 54 (2016) 3010–3017.","ieee":"F. Hu <i>et al.</i>, “Comparative genomic analysis of Haemophilus haemolyticus and nontypeable Haemophilus influenzae and a new testing scheme for their discrimination,” <i>Journal of Clinical Microbiology</i>, vol. 54, no. 12. American Society for Microbiology, pp. 3010–3017, 2016."},"type":"journal_article","quality_controlled":"1","acknowledgement":"We are grateful to ABCs for providing strains and the Bacterial Meningitis Laboratory for technical support.","month":"12","status":"public","intvolume":"        54","date_published":"2016-12-01T00:00:00Z","doi":"10.1128/JCM.01511-16","day":"01","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121393/","open_access":"1"}],"oa":1,"year":"2016","issue":"12","scopus_import":1,"volume":54,"date_updated":"2021-01-12T06:49:04Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Haemophilus haemolyticus has been recently discovered to have the potential to cause invasive disease. It is closely related to nontypeable Haemophilus influenzae (NT H. influenzae). NT H. influenzae and H. haemolyticus are often misidentified because none of the existing tests targeting the known phenotypes of H. haemolyticus are able to specifically identify H. haemolyticus. Through comparative genomic analysis of H. haemolyticus and NT H. influenzae, we identified genes unique to H. haemolyticus that can be used as targets for the identification of H. haemolyticus. A real-time PCR targeting purT (encoding phosphoribosylglycinamide formyltransferase 2 in the purine synthesis pathway) was developed and evaluated. The lower limit of detection was 40 genomes/PCR; the sensitivity and specificity in detecting H. haemolyticus were 98.9% and 97%, respectively. To improve the discrimination of H. haemolyticus and NT H. influenzae, a testing scheme combining two targets (H. haemolyticus purT and H. influenzae hpd, encoding protein D lipoprotein) was also evaluated and showed 96.7% sensitivity and 98.2% specificity for the identification of H. haemolyticus and 92.8% sensitivity and 100% specificity for the identification of H. influenzae, respectively. The dual-target testing scheme can be used for the diagnosis and surveillance of infection and disease caused by H. haemolyticus and NT H. influenzae.","lang":"eng"}],"language":[{"iso":"eng"}],"author":[{"first_name":"Fang","full_name":"Hu, Fang","last_name":"Hu"},{"last_name":"Rishishwar","full_name":"Rishishwar, Lavanya","first_name":"Lavanya"},{"last_name":"Sivadas","full_name":"Sivadas, Ambily","first_name":"Ambily"},{"first_name":"Gabriel","id":"315BCD80-F248-11E8-B48F-1D18A9856A87","full_name":"Mitchell, Gabriel","last_name":"Mitchell"},{"first_name":"Jordan","last_name":"King","full_name":"King, Jordan"},{"full_name":"Murphy, Timothy","last_name":"Murphy","first_name":"Timothy"},{"last_name":"Gilsdorf","full_name":"Gilsdorf, Janet","first_name":"Janet"},{"last_name":"Mayer","full_name":"Mayer, Leonard","first_name":"Leonard"},{"full_name":"Wang, Xin","last_name":"Wang","first_name":"Xin"}],"publication_status":"published","publist_id":"6146","publisher":"American Society for Microbiology","_id":"1203","department":[{"_id":"GaTk"}],"title":"Comparative genomic analysis of Haemophilus haemolyticus and nontypeable Haemophilus influenzae and a new testing scheme for their discrimination","page":"3010 - 3017"},{"department":[{"_id":"MiLe"}],"day":"01","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1603.00299"}],"title":"Surprises in numerical expressions of physical constants","oa":1,"page":"609 - 612","status":"public","publication_status":"published","publisher":"Mathematical Association of America","date_published":"2016-06-01T00:00:00Z","doi":"10.4169/amer.math.monthly.123.6.609","publist_id":"6143","intvolume":"       123","_id":"1204","quality_controlled":"1","date_updated":"2021-01-12T06:49:04Z","abstract":[{"lang":"eng","text":"In science, as in life, &quot;surprises&quot; can be adequately appreciated only in the presence of a null model, what we expect a priori. In physics, theories sometimes express the values of dimensionless physical constants as combinations of mathematical constants like π or e. The inverse problem also arises, whereby the measured value of a physical constant admits a &quot;surprisingly&quot; simple approximation in terms of well-known mathematical constants. Can we estimate the probability for this to be a mere coincidence, rather than an inkling of some theory? We answer the question in the most naive form."}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"month":"06","author":[{"last_name":"Amir","full_name":"Amir, Ariel","first_name":"Ariel"},{"orcid":"0000-0002-6990-7802","first_name":"Mikhail","full_name":"Lemeshko, Mikhail","last_name":"Lemeshko","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Tokieda","full_name":"Tokieda, Tadashi","first_name":"Tadashi"}],"issue":"6","scopus_import":1,"publication":"American Mathematical Monthly","year":"2016","citation":{"ama":"Amir A, Lemeshko M, Tokieda T. Surprises in numerical expressions of physical constants. <i>American Mathematical Monthly</i>. 2016;123(6):609-612. doi:<a href=\"https://doi.org/10.4169/amer.math.monthly.123.6.609\">10.4169/amer.math.monthly.123.6.609</a>","mla":"Amir, Ariel, et al. “Surprises in Numerical Expressions of Physical Constants.” <i>American Mathematical Monthly</i>, vol. 123, no. 6, Mathematical Association of America, 2016, pp. 609–12, doi:<a href=\"https://doi.org/10.4169/amer.math.monthly.123.6.609\">10.4169/amer.math.monthly.123.6.609</a>.","apa":"Amir, A., Lemeshko, M., &#38; Tokieda, T. (2016). Surprises in numerical expressions of physical constants. <i>American Mathematical Monthly</i>. Mathematical Association of America. <a href=\"https://doi.org/10.4169/amer.math.monthly.123.6.609\">https://doi.org/10.4169/amer.math.monthly.123.6.609</a>","ieee":"A. Amir, M. Lemeshko, and T. Tokieda, “Surprises in numerical expressions of physical constants,” <i>American Mathematical Monthly</i>, vol. 123, no. 6. Mathematical Association of America, pp. 609–612, 2016.","short":"A. Amir, M. Lemeshko, T. Tokieda, American Mathematical Monthly 123 (2016) 609–612.","chicago":"Amir, Ariel, Mikhail Lemeshko, and Tadashi Tokieda. “Surprises in Numerical Expressions of Physical Constants.” <i>American Mathematical Monthly</i>. Mathematical Association of America, 2016. <a href=\"https://doi.org/10.4169/amer.math.monthly.123.6.609\">https://doi.org/10.4169/amer.math.monthly.123.6.609</a>.","ista":"Amir A, Lemeshko M, Tokieda T. 2016. Surprises in numerical expressions of physical constants. American Mathematical Monthly. 123(6), 609–612."},"oa_version":"Preprint","date_created":"2018-12-11T11:50:42Z","type":"journal_article","volume":123},{"conference":{"end_date":"2016-11-11","location":"Limassol, Cyprus","name":"FM: International Symposium on Formal Methods","start_date":"2016-11-09"},"author":[{"first_name":"Yu","full_name":"Jiang, Yu","last_name":"Jiang"},{"first_name":"Han","full_name":"Liu, Han","last_name":"Liu"},{"first_name":"Houbing","full_name":"Song, Houbing","last_name":"Song"},{"first_name":"Hui","id":"3BDE25AA-F248-11E8-B48F-1D18A9856A87","full_name":"Kong, Hui","last_name":"Kong","orcid":"0000-0002-3066-6941"},{"first_name":"Ming","last_name":"Gu","full_name":"Gu, Ming"},{"last_name":"Sun","full_name":"Sun, Jiaguang","first_name":"Jiaguang"},{"first_name":"Lui","full_name":"Sha, Lui","last_name":"Sha"}],"language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"In this paper, we present a formal model-driven engineering approach to establishing a safety-assured implementation of Multifunction vehicle bus controller (MVBC) based on the generic reference models and requirements described in the International Electrotechnical Commission (IEC) standard IEC-61375. First, the generic models described in IEC-61375 are translated into a network of timed automata, and some safety requirements tested in IEC-61375 are formalized as timed computation tree logic (TCTL) formulas. With the help of Uppaal, we check and debug whether the timed automata satisfy the formulas or not. Within this step, several logic inconsistencies in the original standard are detected and corrected. Then, we apply the tool Times to generate C code from the verified model, which was later synthesized into a real MVBC chip. Finally, the runtime verification tool RMOR is applied to verify some safety requirements at the implementation level. We set up a real platform with worldwide mostly used MVBC D113, and verify the correctness and the scalability of the synthesized MVBC chip more comprehensively. The errors in the standard has been confirmed and the resulted MVBC has been deployed in real train communication network."}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","file":[{"checksum":"fea0b3fae9a2a42e8bfec59840e30d8c","file_name":"IST-2017-783-v1+1_FM-Safety-Assured-Development-of-MVBC.pdf","date_updated":"2020-07-14T12:44:39Z","file_id":"4673","relation":"main_file","content_type":"application/pdf","access_level":"open_access","creator":"system","file_size":281501,"date_created":"2018-12-12T10:08:13Z"}],"date_updated":"2023-09-18T08:12:48Z","has_accepted_license":"1","volume":9995,"scopus_import":1,"year":"2016","page":"757 - 763","title":"Safety assured formal model driven design of the multifunction vehicle bus controller","project":[{"name":"Rigorous Systems Engineering","call_identifier":"FWF","_id":"25832EC2-B435-11E9-9278-68D0E5697425","grant_number":"S 11407_N23"},{"grant_number":"Z211","call_identifier":"FWF","name":"The Wittgenstein Prize","_id":"25F42A32-B435-11E9-9278-68D0E5697425"}],"alternative_title":["LNCS"],"department":[{"_id":"ToHe"}],"_id":"1205","publisher":"Springer","publist_id":"6144","publication_status":"published","ddc":["004"],"file_date_updated":"2020-07-14T12:44:39Z","pubrep_id":"783","month":"11","acknowledgement":"This research is sponsored in part by NSFC Program (No. 91218302, No. 61527812), National Science and Technology Major Project (No. 2016ZX01038101), Tsinghua University Initiative Scientific Research Program (20131089331), MIIT IT funds (Research and application of TCN key technologies) of China, and the National Key Technology R&D Program (No. 2015BAG14B01-02), Austrian Science Fund (FWF) under grants S11402-N23 (RiSE/SHiNE) and Z211-N23.\r\n","quality_controlled":"1","type":"conference","citation":{"ama":"Jiang Y, Liu H, Song H, et al. Safety assured formal model driven design of the multifunction vehicle bus controller. In: Vol 9995. Springer; 2016:757-763. doi:<a href=\"https://doi.org/10.1007/978-3-319-48989-6_47\">10.1007/978-3-319-48989-6_47</a>","apa":"Jiang, Y., Liu, H., Song, H., Kong, H., Gu, M., Sun, J., &#38; Sha, L. (2016). Safety assured formal model driven design of the multifunction vehicle bus controller (Vol. 9995, pp. 757–763). Presented at the FM: International Symposium on Formal Methods, Limassol, Cyprus: Springer. <a href=\"https://doi.org/10.1007/978-3-319-48989-6_47\">https://doi.org/10.1007/978-3-319-48989-6_47</a>","mla":"Jiang, Yu, et al. <i>Safety Assured Formal Model Driven Design of the Multifunction Vehicle Bus Controller</i>. Vol. 9995, Springer, 2016, pp. 757–63, doi:<a href=\"https://doi.org/10.1007/978-3-319-48989-6_47\">10.1007/978-3-319-48989-6_47</a>.","ieee":"Y. Jiang <i>et al.</i>, “Safety assured formal model driven design of the multifunction vehicle bus controller,” presented at the FM: International Symposium on Formal Methods, Limassol, Cyprus, 2016, vol. 9995, pp. 757–763.","short":"Y. Jiang, H. Liu, H. Song, H. Kong, M. Gu, J. Sun, L. Sha, in:, Springer, 2016, pp. 757–763.","ista":"Jiang Y, Liu H, Song H, Kong H, Gu M, Sun J, Sha L. 2016. Safety assured formal model driven design of the multifunction vehicle bus controller. FM: International Symposium on Formal Methods, LNCS, vol. 9995, 757–763.","chicago":"Jiang, Yu, Han Liu, Houbing Song, Hui Kong, Ming Gu, Jiaguang Sun, and Lui Sha. “Safety Assured Formal Model Driven Design of the Multifunction Vehicle Bus Controller,” 9995:757–63. Springer, 2016. <a href=\"https://doi.org/10.1007/978-3-319-48989-6_47\">https://doi.org/10.1007/978-3-319-48989-6_47</a>."},"oa_version":"Submitted Version","date_created":"2018-12-11T11:50:42Z","oa":1,"day":"08","doi":"10.1007/978-3-319-48989-6_47","date_published":"2016-11-08T00:00:00Z","intvolume":"      9995","related_material":{"record":[{"relation":"later_version","id":"434","status":"public"}]},"status":"public"},{"date_updated":"2021-01-12T06:49:05Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"We study a polar molecule immersed in a superfluid environment, such as a helium nanodroplet or a Bose–Einstein condensate, in the presence of a strong electrostatic field. We show that coupling of the molecular pendular motion, induced by the field, to the fluctuating bath leads to formation of pendulons—spherical harmonic librators dressed by a field of many-particle excitations. We study the behavior of the pendulon in a broad range of molecule–bath and molecule–field interaction strengths, and reveal that its spectrum features a series of instabilities which are absent in the field-free case of the angulon quasiparticle. Furthermore, we show that an external field allows to fine-tune the positions of these instabilities in the molecular rotational spectrum. This opens the door to detailed experimental studies of redistribution of orbital angular momentum in many-particle systems. © 2016 Wiley-VCH Verlag GmbH &amp; Co. KGaA, Weinheim","lang":"eng"}],"language":[{"iso":"eng"}],"author":[{"last_name":"Redchenko","id":"2C21D6E8-F248-11E8-B48F-1D18A9856A87","full_name":"Redchenko, Elena","first_name":"Elena"},{"full_name":"Lemeshko, Mikhail","last_name":"Lemeshko","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","first_name":"Mikhail","orcid":"0000-0002-6990-7802"}],"year":"2016","scopus_import":1,"issue":"22","volume":17,"department":[{"_id":"JoFi"},{"_id":"MiLe"}],"project":[{"grant_number":"665385","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"International IST Doctoral Program"}],"title":"Libration of strongly oriented polar molecules inside a superfluid","page":"3649 - 3654","publication_status":"published","publist_id":"6140","publisher":"Wiley-Blackwell","_id":"1206","ec_funded":1,"quality_controlled":"1","month":"09","publication":"ChemPhysChem","date_created":"2018-12-11T11:50:43Z","citation":{"apa":"Redchenko, E., &#38; Lemeshko, M. (2016). Libration of strongly oriented polar molecules inside a superfluid. <i>ChemPhysChem</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/cphc.201601042\">https://doi.org/10.1002/cphc.201601042</a>","mla":"Redchenko, Elena, and Mikhail Lemeshko. “Libration of Strongly Oriented Polar Molecules inside a Superfluid.” <i>ChemPhysChem</i>, vol. 17, no. 22, Wiley-Blackwell, 2016, pp. 3649–54, doi:<a href=\"https://doi.org/10.1002/cphc.201601042\">10.1002/cphc.201601042</a>.","ama":"Redchenko E, Lemeshko M. Libration of strongly oriented polar molecules inside a superfluid. <i>ChemPhysChem</i>. 2016;17(22):3649-3654. doi:<a href=\"https://doi.org/10.1002/cphc.201601042\">10.1002/cphc.201601042</a>","chicago":"Redchenko, Elena, and Mikhail Lemeshko. “Libration of Strongly Oriented Polar Molecules inside a Superfluid.” <i>ChemPhysChem</i>. Wiley-Blackwell, 2016. <a href=\"https://doi.org/10.1002/cphc.201601042\">https://doi.org/10.1002/cphc.201601042</a>.","ista":"Redchenko E, Lemeshko M. 2016. Libration of strongly oriented polar molecules inside a superfluid. ChemPhysChem. 17(22), 3649–3654.","short":"E. Redchenko, M. Lemeshko, ChemPhysChem 17 (2016) 3649–3654.","ieee":"E. Redchenko and M. Lemeshko, “Libration of strongly oriented polar molecules inside a superfluid,” <i>ChemPhysChem</i>, vol. 17, no. 22. Wiley-Blackwell, pp. 3649–3654, 2016."},"oa_version":"Preprint","type":"journal_article","main_file_link":[{"url":"https://arxiv.org/abs/1609.08161","open_access":"1"}],"day":"18","oa":1,"status":"public","intvolume":"        17","date_published":"2016-09-18T00:00:00Z","doi":"10.1002/cphc.201601042"},{"month":"11","quality_controlled":"1","acknowledgement":"J.A.S supported in part by a Medical Research D.G.Council UK Ph.D. fellowship.\r\nThis work was supported in part by European Union's 2020 Research and Innovation Program under Grant 701309. \r\n","type":"journal_article","publication":"Journal of Biological Chemistry","date_created":"2018-12-11T11:50:44Z","oa_version":"Submitted Version","citation":{"ama":"Letts JA, Degliesposti G, Fiedorczuk K, Skehel M, Sazanov LA. Purification of ovine respiratory complex i results in a highly active and stable preparation. <i>Journal of Biological Chemistry</i>. 2016;291(47):24657-24675. doi:<a href=\"https://doi.org/10.1074/jbc.M116.735142\">10.1074/jbc.M116.735142</a>","mla":"Letts, James A., et al. “Purification of Ovine Respiratory Complex i Results in a Highly Active and Stable Preparation.” <i>Journal of Biological Chemistry</i>, vol. 291, no. 47, American Society for Biochemistry and Molecular Biology, 2016, pp. 24657–75, doi:<a href=\"https://doi.org/10.1074/jbc.M116.735142\">10.1074/jbc.M116.735142</a>.","apa":"Letts, J. A., Degliesposti, G., Fiedorczuk, K., Skehel, M., &#38; Sazanov, L. A. (2016). Purification of ovine respiratory complex i results in a highly active and stable preparation. <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology. <a href=\"https://doi.org/10.1074/jbc.M116.735142\">https://doi.org/10.1074/jbc.M116.735142</a>","ieee":"J. A. Letts, G. Degliesposti, K. Fiedorczuk, M. Skehel, and L. A. Sazanov, “Purification of ovine respiratory complex i results in a highly active and stable preparation,” <i>Journal of Biological Chemistry</i>, vol. 291, no. 47. American Society for Biochemistry and Molecular Biology, pp. 24657–24675, 2016.","short":"J.A. Letts, G. Degliesposti, K. Fiedorczuk, M. Skehel, L.A. Sazanov, Journal of Biological Chemistry 291 (2016) 24657–24675.","chicago":"Letts, James A, Gianluca Degliesposti, Karol Fiedorczuk, Mark Skehel, and Leonid A Sazanov. “Purification of Ovine Respiratory Complex i Results in a Highly Active and Stable Preparation.” <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology, 2016. <a href=\"https://doi.org/10.1074/jbc.M116.735142\">https://doi.org/10.1074/jbc.M116.735142</a>.","ista":"Letts JA, Degliesposti G, Fiedorczuk K, Skehel M, Sazanov LA. 2016. Purification of ovine respiratory complex i results in a highly active and stable preparation. Journal of Biological Chemistry. 291(47), 24657–24675."},"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114416/","open_access":"1"}],"day":"18","oa":1,"intvolume":"       291","doi":"10.1074/jbc.M116.735142","date_published":"2016-11-18T00:00:00Z","status":"public","language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-9864-3586","first_name":"James A","id":"322DA418-F248-11E8-B48F-1D18A9856A87","full_name":"Letts, James A","last_name":"Letts"},{"full_name":"Degliesposti, Gianluca","last_name":"Degliesposti","first_name":"Gianluca"},{"id":"5BFF67CE-02D1-11E9-B11A-A5A4D7DFFFD0","last_name":"Fiedorczuk","full_name":"Fiedorczuk, Karol","first_name":"Karol"},{"last_name":"Skehel","full_name":"Skehel, Mark","first_name":"Mark"},{"orcid":"0000-0002-0977-7989","last_name":"Sazanov","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","full_name":"Sazanov, Leonid A","first_name":"Leonid A"}],"date_updated":"2021-01-12T06:49:06Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"NADH-ubiquinone oxidoreductase (complex I) is the largest (∼1 MDa) and the least characterized complex of the mitochondrial electron transport chain. Because of the ease of sample availability, previous work has focused almost exclusively on bovine complex I. However, only medium resolution structural analyses of this complex have been reported. Working with other mammalian complex I homologues is a potential approach for overcoming these limitations. Due to the inherent difficulty of expressing large membrane protein complexes, screening of complex I homologues is limited to large mammals reared for human consumption. The high sequence identity among these available sources may preclude the benefits of screening. Here, we report the characterization of complex I purified from Ovis aries (ovine) heart mitochondria. All 44 unique subunits of the intact complex were identified by mass spectrometry. We identified differences in the subunit composition of subcomplexes of ovine complex I as compared with bovine, suggesting differential stability of inter-subunit interactions within the complex. Furthermore, the 42-kDa subunit, which is easily lost from the bovine enzyme, remains tightly bound to ovine complex I. Additionally, we developed a novel purification protocol for highly active and stable mitochondrial complex I using the branched-chain detergent lauryl maltose neopentyl glycol. Our data demonstrate that, although closely related, significant differences exist between the biochemical properties of complex I prepared from ovine and bovine mitochondria and that ovine complex I represents a suitable alternative target for further structural studies. "}],"volume":291,"year":"2016","scopus_import":1,"issue":"47","project":[{"_id":"2593EBD6-B435-11E9-9278-68D0E5697425","name":"Atomic-Resolution Structures of Mitochondrial Respiratory Chain Supercomplexes (FEBS)"},{"grant_number":"701309","call_identifier":"H2020","name":"Atomic-Resolution Structures of Mitochondrial Respiratory Chain Supercomplexes (H2020)","_id":"2590DB08-B435-11E9-9278-68D0E5697425"}],"page":"24657 - 24675","title":"Purification of ovine respiratory complex i results in a highly active and stable preparation","department":[{"_id":"LeSa"}],"publist_id":"6139","publisher":"American Society for Biochemistry and Molecular Biology","_id":"1209","ec_funded":1,"publication_status":"published"},{"day":"21","oa":1,"status":"public","intvolume":"        26","date_published":"2016-11-21T00:00:00Z","doi":"10.1016/j.cub.2016.08.067","quality_controlled":"1","acknowledgement":"We thank Dr. Jie Li (Key Laboratory of Plant Molecular Physiology, Chinese Academy of Science, China) for the pPIN3::PIN3-GFP/DII::VENUS line and Martine De Cock for help in preparing the manuscript. This work was supported by the European Research Council (project ERC-2011-StG-20101109-PSDP), by the Czech Science Foundation GAČR (GA13-40637S) to J.F., and by the Ministry of Education, Youth and Sports of the Czech Republic under the project CEITEC 2020 (LQ1601) to H.S.R. H.R. is indebted to the Agency for Innovation by Science and Technology (IWT) for a predoctoral fellowship.\r\n","pubrep_id":"1008","month":"11","publication":"Current Biology","date_created":"2018-12-11T11:50:44Z","citation":{"ama":"Rakusová H, Abbas M, Han H, Song S, Robert H, Friml J. Termination of shoot gravitropic responses by auxin feedback on PIN3 polarity. <i>Current Biology</i>. 2016;26(22):3026-3032. doi:<a href=\"https://doi.org/10.1016/j.cub.2016.08.067\">10.1016/j.cub.2016.08.067</a>","mla":"Rakusová, Hana, et al. “Termination of Shoot Gravitropic Responses by Auxin Feedback on PIN3 Polarity.” <i>Current Biology</i>, vol. 26, no. 22, Cell Press, 2016, pp. 3026–32, doi:<a href=\"https://doi.org/10.1016/j.cub.2016.08.067\">10.1016/j.cub.2016.08.067</a>.","apa":"Rakusová, H., Abbas, M., Han, H., Song, S., Robert, H., &#38; Friml, J. (2016). Termination of shoot gravitropic responses by auxin feedback on PIN3 polarity. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cub.2016.08.067\">https://doi.org/10.1016/j.cub.2016.08.067</a>","ieee":"H. Rakusová, M. Abbas, H. Han, S. Song, H. Robert, and J. Friml, “Termination of shoot gravitropic responses by auxin feedback on PIN3 polarity,” <i>Current Biology</i>, vol. 26, no. 22. Cell Press, pp. 3026–3032, 2016.","short":"H. Rakusová, M. Abbas, H. Han, S. Song, H. Robert, J. Friml, Current Biology 26 (2016) 3026–3032.","ista":"Rakusová H, Abbas M, Han H, Song S, Robert H, Friml J. 2016. Termination of shoot gravitropic responses by auxin feedback on PIN3 polarity. Current Biology. 26(22), 3026–3032.","chicago":"Rakusová, Hana, Mohamad Abbas, Huibin Han, Siyuan Song, Hélène Robert, and Jiří Friml. “Termination of Shoot Gravitropic Responses by Auxin Feedback on PIN3 Polarity.” <i>Current Biology</i>. Cell Press, 2016. <a href=\"https://doi.org/10.1016/j.cub.2016.08.067\">https://doi.org/10.1016/j.cub.2016.08.067</a>."},"oa_version":"Submitted Version","type":"journal_article","department":[{"_id":"JiFr"}],"project":[{"grant_number":"282300","_id":"25716A02-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"Polarity and subcellular dynamics in plants"}],"title":"Termination of shoot gravitropic responses by auxin feedback on PIN3 polarity","page":"3026 - 3032","file_date_updated":"2020-07-14T12:44:39Z","ddc":["581"],"publication_status":"published","publist_id":"6138","publisher":"Cell Press","_id":"1212","ec_funded":1,"date_updated":"2021-01-12T06:49:08Z","file":[{"checksum":"79ed2498185a027cf51a8f88100379e6","date_updated":"2020-07-14T12:44:39Z","file_name":"IST-2018-1008-v1+1_Rakusova_CurrBiol_2016_proof.pdf","date_created":"2018-12-12T10:09:33Z","file_size":5391923,"relation":"main_file","file_id":"4757","creator":"system","content_type":"application/pdf","access_level":"open_access"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Plants adjust their growth according to gravity. Gravitropism involves gravity perception, signal transduction, and asymmetric growth response, with organ bending as a consequence [1]. Asymmetric growth results from the asymmetric distribution of the plant-specific signaling molecule auxin [2] that is generated by lateral transport, mediated in the hypocotyl predominantly by the auxin transporter PIN-FORMED3 (PIN3) [3–5]. Gravity stimulation polarizes PIN3 to the bottom sides of endodermal cells, correlating with increased auxin accumulation in adjacent tissues at the lower side of the stimulated organ, where auxin induces cell elongation and, hence, organ bending. A curvature response allows the hypocotyl to resume straight growth at a defined angle [6], implying that at some point auxin symmetry is restored to prevent overbending. Here, we present initial insights into cellular and molecular mechanisms that lead to the termination of the tropic response. We identified an auxin feedback on PIN3 polarization as underlying mechanism that restores symmetry of the PIN3-dependent auxin flow. Thus, two mechanistically distinct PIN3 polarization events redirect auxin fluxes at different time points of the gravity response: first, gravity-mediated redirection of PIN3-mediated auxin flow toward the lower hypocotyl side, where auxin gradually accumulates and promotes growth, and later PIN3 polarization to the opposite cell side, depleting this auxin maximum to end the bending. Accordingly, genetic or pharmacological interference with the late PIN3 polarization prevents termination of the response and leads to hypocotyl overbending. This observation reveals a role of auxin feedback on PIN polarity in the termination of the tropic response. © 2016 Elsevier Ltd","lang":"eng"}],"language":[{"iso":"eng"}],"author":[{"full_name":"Rakusová, Hana","last_name":"Rakusová","first_name":"Hana"},{"first_name":"Mohamad","last_name":"Abbas","id":"47E8FC1C-F248-11E8-B48F-1D18A9856A87","full_name":"Abbas, Mohamad"},{"first_name":"Huibin","id":"31435098-F248-11E8-B48F-1D18A9856A87","last_name":"Han","full_name":"Han, Huibin"},{"first_name":"Siyuan","full_name":"Song, Siyuan","last_name":"Song"},{"first_name":"Hélène","full_name":"Robert, Hélène","last_name":"Robert"},{"orcid":"0000-0002-8302-7596","first_name":"Jirí","full_name":"Friml, Jirí","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"year":"2016","scopus_import":1,"issue":"22","volume":26,"has_accepted_license":"1"},{"project":[{"name":"Limits to selection in biology and in evolutionary computation","call_identifier":"FP7","_id":"25B07788-B435-11E9-9278-68D0E5697425","grant_number":"250152"},{"_id":"25B67606-B435-11E9-9278-68D0E5697425","name":"L'OREAL Fellowship"}],"page":"721 - 732","title":"The role of recombination in evolutionary rescue","department":[{"_id":"NiBa"}],"publist_id":"6091","publisher":"Genetics Society of America","_id":"1241","ec_funded":1,"das_tickbox":"1","publication_status":"published","ddc":["570"],"language":[{"iso":"eng"}],"author":[{"orcid":"0000-0001-9435-2813","full_name":"Uecker, Hildegard","id":"2DB8F68A-F248-11E8-B48F-1D18A9856A87","last_name":"Uecker","first_name":"Hildegard"},{"last_name":"Hermisson","full_name":"Hermisson, Joachim","first_name":"Joachim"}],"date_updated":"2026-06-18T07:59:00Z","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"How likely is it that a population escapes extinction through adaptive evolution? The answer to this question is of great relevance in conservation biology, where we aim at species’ rescue and the maintenance of biodiversity, and in agriculture and medicine, where we seek to hamper the emergence of pesticide or drug resistance. By reshuffling the genome, recombination has two antagonistic effects on the probability of evolutionary rescue: It generates and it breaks up favorable gene combinations. Which of the two effects prevails depends on the fitness effects of mutations and on the impact of stochasticity on the allele frequencies. In this article, we analyze a mathematical model for rescue after a sudden environmental change when adaptation is contingent on mutations at two loci. The analysis reveals a complex nonlinear dependence of population survival on recombination. We moreover find that, counterintuitively, a fast eradication of the wild type can promote rescue in the presence of recombination. The model also shows that two-step rescue is not unlikely to happen and can even be more likely than single-step rescue (where adaptation relies on a single mutation), depending on the circumstances.","lang":"eng"}],"volume":202,"year":"2016","scopus_import":"1","issue":"2","day":"01","main_file_link":[{"open_access":"1","url":"http://biorxiv.org/content/early/2015/07/06/022020.abstract"}],"oa":1,"intvolume":"       202","date_published":"2016-02-01T00:00:00Z","doi":"10.1534/genetics.115.180299","status":"public","month":"02","quality_controlled":"1","acknowledgement":"This work was made possible by a “For Women in Science” fellowship (L’Oréal Österreich in cooperation with the Austrian Commission for the United Nations Educational, Scientific, and Cultural Organization and the Austrian Academy of Sciences with financial support from the Federal Ministry for Science and Research Austria) and European Research Council grant 250152 (to Nick Barton).","type":"journal_article","publication":"Genetics","date_created":"2018-12-11T11:50:54Z","citation":{"short":"H. Uecker, J. Hermisson, Genetics 202 (2016) 721–732.","ieee":"H. Uecker and J. Hermisson, “The role of recombination in evolutionary rescue,” <i>Genetics</i>, vol. 202, no. 2. Genetics Society of America, pp. 721–732, 2016.","chicago":"Uecker, Hildegard, and Joachim Hermisson. “The Role of Recombination in Evolutionary Rescue.” <i>Genetics</i>. Genetics Society of America, 2016. <a href=\"https://doi.org/10.1534/genetics.115.180299\">https://doi.org/10.1534/genetics.115.180299</a>.","ista":"Uecker H, Hermisson J. 2016. The role of recombination in evolutionary rescue. Genetics. 202(2), 721–732.","ama":"Uecker H, Hermisson J. The role of recombination in evolutionary rescue. <i>Genetics</i>. 2016;202(2):721-732. doi:<a href=\"https://doi.org/10.1534/genetics.115.180299\">10.1534/genetics.115.180299</a>","apa":"Uecker, H., &#38; Hermisson, J. (2016). The role of recombination in evolutionary rescue. <i>Genetics</i>. Genetics Society of America. <a href=\"https://doi.org/10.1534/genetics.115.180299\">https://doi.org/10.1534/genetics.115.180299</a>","mla":"Uecker, Hildegard, and Joachim Hermisson. “The Role of Recombination in Evolutionary Rescue.” <i>Genetics</i>, vol. 202, no. 2, Genetics Society of America, 2016, pp. 721–32, doi:<a href=\"https://doi.org/10.1534/genetics.115.180299\">10.1534/genetics.115.180299</a>."},"oa_version":"Preprint"},{"publication_identifier":{"eissn":["1727-5652"],"issn":["0022-1430"]},"author":[{"first_name":"Jakob F.","last_name":"Steiner","full_name":"Steiner, Jakob F."},{"full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca"},{"full_name":"Buri, Pascal","last_name":"Buri","first_name":"Pascal"},{"full_name":"Miles, Evan S.","last_name":"Miles","first_name":"Evan S."},{"last_name":"Immerzeel","full_name":"Immerzeel, Walter W.","first_name":"Walter W."},{"first_name":"Tim D.","full_name":"Reid, Tim D.","last_name":"Reid"}],"language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"Ice cliffs have been identified as a reason for higher ablation rates on debris-covered glaciers than are implied by the insulation effects of the debris. This study aims to improve our understanding of cliff backwasting, and the role of radiative fluxes in particular. An energy-balance model is forced with new data gathered in May and October 2013 on Lirung Glacier, Nepalese Himalaya. Observations show substantial variability in melt between cliffs, between locations on any cliff and between seasons. Using a high-resolution digital elevation model we calculate longwave fluxes incident to the cliff from surrounding terrain and include the effect of local shading on shortwave radiation. This is an advance over previous studies, that made simplified assumptions on cliff geometry and radiative fluxes. Measured melt rates varied between 3.25 and 8.6 cm d−1 in May and 0.18 and 1.34 cm d−1 in October. Model results reproduce the strong variability in space and time, suggesting considerable differences in radiative fluxes over one cliff. In October the model fails to reproduce stake readings, probably due to the lack of a refreezing component. Disregarding local topography can lead to overestimation of melt at the point scale by up to ∼9%."}],"date_updated":"2023-02-24T09:43:14Z","article_processing_charge":"No","volume":61,"year":"2015","scopus_import":"1","issue":"229","page":"889-907","title":"Modelling ice-cliff backwasting on a debris-covered glacier in the Nepalese Himalaya","_id":"12626","article_type":"original","publisher":"International Glaciological Society","publication_status":"published","month":"07","quality_controlled":"1","type":"journal_article","date_created":"2023-02-20T08:16:01Z","citation":{"ama":"Steiner JF, Pellicciotti F, Buri P, Miles ES, Immerzeel WW, Reid TD. Modelling ice-cliff backwasting on a debris-covered glacier in the Nepalese Himalaya. <i>Journal of Glaciology</i>. 2015;61(229):889-907. doi:<a href=\"https://doi.org/10.3189/2015jog14j194\">10.3189/2015jog14j194</a>","mla":"Steiner, Jakob F., et al. “Modelling Ice-Cliff Backwasting on a Debris-Covered Glacier in the Nepalese Himalaya.” <i>Journal of Glaciology</i>, vol. 61, no. 229, International Glaciological Society, 2015, pp. 889–907, doi:<a href=\"https://doi.org/10.3189/2015jog14j194\">10.3189/2015jog14j194</a>.","apa":"Steiner, J. F., Pellicciotti, F., Buri, P., Miles, E. S., Immerzeel, W. W., &#38; Reid, T. D. (2015). Modelling ice-cliff backwasting on a debris-covered glacier in the Nepalese Himalaya. <i>Journal of Glaciology</i>. International Glaciological Society. <a href=\"https://doi.org/10.3189/2015jog14j194\">https://doi.org/10.3189/2015jog14j194</a>","ieee":"J. F. Steiner, F. Pellicciotti, P. Buri, E. S. Miles, W. W. Immerzeel, and T. D. Reid, “Modelling ice-cliff backwasting on a debris-covered glacier in the Nepalese Himalaya,” <i>Journal of Glaciology</i>, vol. 61, no. 229. International Glaciological Society, pp. 889–907, 2015.","short":"J.F. Steiner, F. Pellicciotti, P. Buri, E.S. Miles, W.W. Immerzeel, T.D. Reid, Journal of Glaciology 61 (2015) 889–907.","ista":"Steiner JF, Pellicciotti F, Buri P, Miles ES, Immerzeel WW, Reid TD. 2015. Modelling ice-cliff backwasting on a debris-covered glacier in the Nepalese Himalaya. Journal of Glaciology. 61(229), 889–907.","chicago":"Steiner, Jakob F., Francesca Pellicciotti, Pascal Buri, Evan S. Miles, Walter W. Immerzeel, and Tim D. Reid. “Modelling Ice-Cliff Backwasting on a Debris-Covered Glacier in the Nepalese Himalaya.” <i>Journal of Glaciology</i>. International Glaciological Society, 2015. <a href=\"https://doi.org/10.3189/2015jog14j194\">https://doi.org/10.3189/2015jog14j194</a>."},"oa_version":"Published Version","publication":"Journal of Glaciology","oa":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.3189/2015JoG14J194"}],"day":"01","extern":"1","intvolume":"        61","date_published":"2015-07-01T00:00:00Z","doi":"10.3189/2015jog14j194","status":"public"},{"issue":"227","scopus_import":"1","year":"2015","volume":61,"article_processing_charge":"No","date_updated":"2023-02-24T09:40:30Z","abstract":[{"lang":"eng","text":"Spatial evolution of supraglacial debris cover on mountain glaciers is a largely unmonitored and poorly understood phenomenon that directly affects glacier melt. Supraglacial debris cover for 93 glaciers in the Karakoram, northern Pakistan, was mapped from Landsat imagery acquired in 1977, 1998, 2009 and 2014. Surge-type glaciers occupy 41% of the study area and were considered separately. The time series of debris-covered surface area change shows a mean value of zero or near-zero change for both surging and non-surging glaciers. An increase in debris-covered area is often associated with negative regional mass balances. We extend this logic to suggest that the stable regional mass balances in the Karakoram explain the zero or near-zero change in debris-covered area. This coupling of trends combined with our 37 year time series of data suggests the Karakoram anomaly extends further back in time than previously known."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"author":[{"full_name":"Herreid, Sam","last_name":"Herreid","first_name":"Sam"},{"first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","last_name":"Pellicciotti","full_name":"Pellicciotti, Francesca"},{"last_name":"Ayala","full_name":"Ayala, Alvaro","first_name":"Alvaro"},{"full_name":"Chesnokova, Anna","last_name":"Chesnokova","first_name":"Anna"},{"first_name":"Christian","last_name":"Kienholz","full_name":"Kienholz, Christian"},{"full_name":"Shea, Joseph","last_name":"Shea","first_name":"Joseph"},{"last_name":"Shrestha","full_name":"Shrestha, Arun","first_name":"Arun"}],"publication_identifier":{"eissn":["1727-5652"],"issn":["0022-1430"]},"publication_status":"published","publisher":"International Glaciological Society","article_type":"original","_id":"12627","title":"Satellite observations show no net change in the percentage of supraglacial debris-covered area in northern Pakistan from 1977 to 2014","page":"524-536","publication":"Journal of Glaciology","oa_version":"Published Version","citation":{"ama":"Herreid S, Pellicciotti F, Ayala A, et al. Satellite observations show no net change in the percentage of supraglacial debris-covered area in northern Pakistan from 1977 to 2014. <i>Journal of Glaciology</i>. 2015;61(227):524-536. doi:<a href=\"https://doi.org/10.3189/2015jog14j227\">10.3189/2015jog14j227</a>","apa":"Herreid, S., Pellicciotti, F., Ayala, A., Chesnokova, A., Kienholz, C., Shea, J., &#38; Shrestha, A. (2015). Satellite observations show no net change in the percentage of supraglacial debris-covered area in northern Pakistan from 1977 to 2014. <i>Journal of Glaciology</i>. International Glaciological Society. <a href=\"https://doi.org/10.3189/2015jog14j227\">https://doi.org/10.3189/2015jog14j227</a>","mla":"Herreid, Sam, et al. “Satellite Observations Show No Net Change in the Percentage of Supraglacial Debris-Covered Area in Northern Pakistan from 1977 to 2014.” <i>Journal of Glaciology</i>, vol. 61, no. 227, International Glaciological Society, 2015, pp. 524–36, doi:<a href=\"https://doi.org/10.3189/2015jog14j227\">10.3189/2015jog14j227</a>.","short":"S. Herreid, F. Pellicciotti, A. Ayala, A. Chesnokova, C. Kienholz, J. Shea, A. Shrestha, Journal of Glaciology 61 (2015) 524–536.","ieee":"S. Herreid <i>et al.</i>, “Satellite observations show no net change in the percentage of supraglacial debris-covered area in northern Pakistan from 1977 to 2014,” <i>Journal of Glaciology</i>, vol. 61, no. 227. International Glaciological Society, pp. 524–536, 2015.","ista":"Herreid S, Pellicciotti F, Ayala A, Chesnokova A, Kienholz C, Shea J, Shrestha A. 2015. Satellite observations show no net change in the percentage of supraglacial debris-covered area in northern Pakistan from 1977 to 2014. Journal of Glaciology. 61(227), 524–536.","chicago":"Herreid, Sam, Francesca Pellicciotti, Alvaro Ayala, Anna Chesnokova, Christian Kienholz, Joseph Shea, and Arun Shrestha. “Satellite Observations Show No Net Change in the Percentage of Supraglacial Debris-Covered Area in Northern Pakistan from 1977 to 2014.” <i>Journal of Glaciology</i>. International Glaciological Society, 2015. <a href=\"https://doi.org/10.3189/2015jog14j227\">https://doi.org/10.3189/2015jog14j227</a>."},"date_created":"2023-02-20T08:16:06Z","type":"journal_article","quality_controlled":"1","month":"05","status":"public","doi":"10.3189/2015jog14j227","date_published":"2015-05-01T00:00:00Z","intvolume":"        61","extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.3189/2015JoG14J227"}],"day":"01","oa":1},{"publication_status":"published","article_type":"original","publisher":"International Glaciological Society","_id":"12628","page":"373-386","title":"Mass-balance changes of the debris-covered glaciers in the Langtang Himal, Nepal, from 1974 to 1999","year":"2015","scopus_import":"1","issue":"226","volume":61,"date_updated":"2023-02-24T09:35:21Z","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Thick debris cover on glaciers can significantly reduce ice melt. However, several studies have suggested that debris-covered glaciers in the Himalaya might have lost mass at a rate similar to debris-free glaciers. We reconstruct elevation and mass changes for the debris-covered glaciers of the upper Langtang valley, Nepalese Himalaya, using a digital elevation model (DEM) from 1974 stereo Hexagon satellite data and the 2000 SRTM (Shuttle Radar Topography Mission) DEM. Uncertainties are high in the accumulation areas, due to data gaps in the SRTM and difficulties with delineation of the glacier borders. Even with these uncertainties, we obtain thinning rates comparable to those of several other studies in the Himalaya. In particular, we obtain a total mass balance for the investigated debris-covered glaciers of the basin of –0.32 ± 0.18 m w.e. a<jats:sup>−1</jats:sup>. However, there are major spatial differences both between glaciers and within any single glacier, exhibiting a very distinct nonlinear mass-balance profile with elevation. Through analysis of surface velocities derived from Landsat ETM+ imagery, we show that thinning occurs in areas of low velocity and low slope. These areas are prone to a general, dynamic decay of surface features and to the development of supraglacial lakes and ice cliffs, which may be responsible for a considerable increase in overall glacier ablation.","lang":"eng"}],"language":[{"iso":"eng"}],"author":[{"first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","last_name":"Pellicciotti","full_name":"Pellicciotti, Francesca"},{"full_name":"Stephan, Christa","last_name":"Stephan","first_name":"Christa"},{"full_name":"Miles, Evan","last_name":"Miles","first_name":"Evan"},{"last_name":"Herreid","full_name":"Herreid, Sam","first_name":"Sam"},{"last_name":"Immerzeel","full_name":"Immerzeel, Walter W.","first_name":"Walter W."},{"full_name":"Bolch, Tobias","last_name":"Bolch","first_name":"Tobias"}],"publication_identifier":{"eissn":["1727-5652"],"issn":["0022-1430"]},"status":"public","intvolume":"        61","doi":"10.3189/2015jog13j237","date_published":"2015-03-01T00:00:00Z","keyword":["Earth-Surface Processes"],"day":"01","main_file_link":[{"url":"https://doi.org/10.3189/2015JoG13J237","open_access":"1"}],"extern":"1","oa":1,"publication":"Journal of Glaciology","date_created":"2023-02-20T08:16:11Z","citation":{"mla":"Pellicciotti, Francesca, et al. “Mass-Balance Changes of the Debris-Covered Glaciers in the Langtang Himal, Nepal, from 1974 to 1999.” <i>Journal of Glaciology</i>, vol. 61, no. 226, International Glaciological Society, 2015, pp. 373–86, doi:<a href=\"https://doi.org/10.3189/2015jog13j237\">10.3189/2015jog13j237</a>.","apa":"Pellicciotti, F., Stephan, C., Miles, E., Herreid, S., Immerzeel, W. W., &#38; Bolch, T. (2015). Mass-balance changes of the debris-covered glaciers in the Langtang Himal, Nepal, from 1974 to 1999. <i>Journal of Glaciology</i>. International Glaciological Society. <a href=\"https://doi.org/10.3189/2015jog13j237\">https://doi.org/10.3189/2015jog13j237</a>","ama":"Pellicciotti F, Stephan C, Miles E, Herreid S, Immerzeel WW, Bolch T. Mass-balance changes of the debris-covered glaciers in the Langtang Himal, Nepal, from 1974 to 1999. <i>Journal of Glaciology</i>. 2015;61(226):373-386. doi:<a href=\"https://doi.org/10.3189/2015jog13j237\">10.3189/2015jog13j237</a>","ista":"Pellicciotti F, Stephan C, Miles E, Herreid S, Immerzeel WW, Bolch T. 2015. Mass-balance changes of the debris-covered glaciers in the Langtang Himal, Nepal, from 1974 to 1999. Journal of Glaciology. 61(226), 373–386.","chicago":"Pellicciotti, Francesca, Christa Stephan, Evan Miles, Sam Herreid, Walter W. Immerzeel, and Tobias Bolch. “Mass-Balance Changes of the Debris-Covered Glaciers in the Langtang Himal, Nepal, from 1974 to 1999.” <i>Journal of Glaciology</i>. International Glaciological Society, 2015. <a href=\"https://doi.org/10.3189/2015jog13j237\">https://doi.org/10.3189/2015jog13j237</a>.","short":"F. Pellicciotti, C. Stephan, E. Miles, S. Herreid, W.W. Immerzeel, T. Bolch, Journal of Glaciology 61 (2015) 373–386.","ieee":"F. Pellicciotti, C. Stephan, E. Miles, S. Herreid, W. W. Immerzeel, and T. Bolch, “Mass-balance changes of the debris-covered glaciers in the Langtang Himal, Nepal, from 1974 to 1999,” <i>Journal of Glaciology</i>, vol. 61, no. 226. International Glaciological Society, pp. 373–386, 2015."},"oa_version":"Published Version","type":"journal_article","quality_controlled":"1","month":"03"},{"abstract":[{"lang":"eng","text":"Meteorological studies in high-mountain environments form the basis of our understanding of catchment hydrology and glacier accumulation and melt processes, yet high-altitude (>4000 m above sea level, asl) observatories are rare. This research presents meteorological data recorded between December 2012 and November 2013 at seven stations in Nepal, ranging in elevation from 3860 to 5360 m asl. Seasonal and diurnal cycles in air temperature, vapour pressure, incoming short-wave and long-wave radiation, atmospheric transmissivity, wind speed, and precipitation are compared between sites. Solar radiation strongly affects diurnal temperature and vapour pressure cycles, but local topography and valley-scale circulations alter wind speed and precipitation cycles. The observed diurnal variability in vertical temperature gradients in all seasons highlights the importance of in situ measurements for melt modelling. The monsoon signal (progressive onset and sharp end) is visible in all data-sets, and the passage of the remnants of Typhoon Phailin in mid-October 2013 provides an interesting case study on the possible effects of such storms on glaciers in the region."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","date_updated":"2023-02-24T09:30:42Z","publication_identifier":{"issn":["0790-0627"],"eissn":["1360-0648"]},"author":[{"first_name":"J.M.","full_name":"Shea, J.M.","last_name":"Shea"},{"last_name":"Wagnon","full_name":"Wagnon, P.","first_name":"P."},{"last_name":"Immerzeel","full_name":"Immerzeel, W.W.","first_name":"W.W."},{"last_name":"Biron","full_name":"Biron, R.","first_name":"R."},{"first_name":"F.","full_name":"Brun, F.","last_name":"Brun"},{"first_name":"Francesca","full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"}],"language":[{"iso":"eng"}],"issue":"2","scopus_import":"1","year":"2015","volume":31,"title":"A comparative high-altitude meteorological analysis from three catchments in the Nepalese Himalaya","page":"174-200","publication_status":"published","_id":"12629","publisher":"Taylor & Francis","article_type":"original","quality_controlled":"1","month":"04","oa_version":"Published Version","citation":{"ieee":"J. M. Shea, P. Wagnon, W. W. Immerzeel, R. Biron, F. Brun, and F. Pellicciotti, “A comparative high-altitude meteorological analysis from three catchments in the Nepalese Himalaya,” <i>International Journal of Water Resources Development</i>, vol. 31, no. 2. Taylor &#38; Francis, pp. 174–200, 2015.","short":"J.M. Shea, P. Wagnon, W.W. Immerzeel, R. Biron, F. Brun, F. Pellicciotti, International Journal of Water Resources Development 31 (2015) 174–200.","chicago":"Shea, J.M., P. Wagnon, W.W. Immerzeel, R. Biron, F. Brun, and Francesca Pellicciotti. “A Comparative High-Altitude Meteorological Analysis from Three Catchments in the Nepalese Himalaya.” <i>International Journal of Water Resources Development</i>. Taylor &#38; Francis, 2015. <a href=\"https://doi.org/10.1080/07900627.2015.1020417\">https://doi.org/10.1080/07900627.2015.1020417</a>.","ista":"Shea JM, Wagnon P, Immerzeel WW, Biron R, Brun F, Pellicciotti F. 2015. A comparative high-altitude meteorological analysis from three catchments in the Nepalese Himalaya. International Journal of Water Resources Development. 31(2), 174–200.","ama":"Shea JM, Wagnon P, Immerzeel WW, Biron R, Brun F, Pellicciotti F. A comparative high-altitude meteorological analysis from three catchments in the Nepalese Himalaya. <i>International Journal of Water Resources Development</i>. 2015;31(2):174-200. doi:<a href=\"https://doi.org/10.1080/07900627.2015.1020417\">10.1080/07900627.2015.1020417</a>","mla":"Shea, J. M., et al. “A Comparative High-Altitude Meteorological Analysis from Three Catchments in the Nepalese Himalaya.” <i>International Journal of Water Resources Development</i>, vol. 31, no. 2, Taylor &#38; Francis, 2015, pp. 174–200, doi:<a href=\"https://doi.org/10.1080/07900627.2015.1020417\">10.1080/07900627.2015.1020417</a>.","apa":"Shea, J. M., Wagnon, P., Immerzeel, W. W., Biron, R., Brun, F., &#38; Pellicciotti, F. (2015). A comparative high-altitude meteorological analysis from three catchments in the Nepalese Himalaya. <i>International Journal of Water Resources Development</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.1080/07900627.2015.1020417\">https://doi.org/10.1080/07900627.2015.1020417</a>"},"date_created":"2023-02-20T08:16:17Z","publication":"International Journal of Water Resources Development","type":"journal_article","keyword":["Water Science and Technology","Development"],"oa":1,"extern":"1","main_file_link":[{"url":"https://doi.org/10.1080/07900627.2015.1020417","open_access":"1"}],"day":"18","status":"public","doi":"10.1080/07900627.2015.1020417","date_published":"2015-04-18T00:00:00Z","intvolume":"        31"},{"has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"scopus_import":"1","year":"2015","language":[{"iso":"eng"}],"publication_identifier":{"isbn":["9780262330275"]},"author":[{"first_name":"Georg S","id":"3A276B68-F248-11E8-B48F-1D18A9856A87","full_name":"Martius, Georg S","last_name":"Martius"},{"full_name":"Olbrich, Eckehard","last_name":"Olbrich","first_name":"Eckehard"}],"conference":{"start_date":"2015-07-20","name":"ECAL: European Conference on Artificial Life","location":"York, United Kingdom","end_date":"2015-07-24"},"article_processing_charge":"No","date_updated":"2023-05-02T07:06:21Z","file":[{"date_updated":"2023-05-02T07:02:59Z","file_name":"2015_ECAL_Martius.pdf","checksum":"880eabe59c9df12f06a882aa1bc4e600","success":1,"date_created":"2023-05-02T07:02:59Z","file_size":1674241,"creator":"dernst","access_level":"open_access","content_type":"application/pdf","relation":"main_file","file_id":"12882"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"MIT Press","ec_funded":1,"_id":"12881","ddc":["000"],"file_date_updated":"2023-05-02T07:02:59Z","publication_status":"published","project":[{"grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme"}],"title":"Quantifying self-organizing behavior of autonomous robots","page":"78","department":[{"_id":"ChLa"}],"type":"conference","publication":"Proceedings of the 13th European Conference on Artificial Life","citation":{"short":"G.S. Martius, E. Olbrich, in:, Proceedings of the 13th European Conference on Artificial Life, MIT Press, 2015, p. 78.","ieee":"G. S. Martius and E. Olbrich, “Quantifying self-organizing behavior of autonomous robots,” in <i>Proceedings of the 13th European Conference on Artificial Life</i>, York, United Kingdom, 2015, p. 78.","chicago":"Martius, Georg S, and Eckehard Olbrich. “Quantifying Self-Organizing Behavior of Autonomous Robots.” In <i>Proceedings of the 13th European Conference on Artificial Life</i>, 78. MIT Press, 2015. <a href=\"https://doi.org/10.7551/978-0-262-33027-5-ch018\">https://doi.org/10.7551/978-0-262-33027-5-ch018</a>.","ista":"Martius GS, Olbrich E. 2015. Quantifying self-organizing behavior of autonomous robots. Proceedings of the 13th European Conference on Artificial Life. ECAL: European Conference on Artificial Life, 78.","ama":"Martius GS, Olbrich E. Quantifying self-organizing behavior of autonomous robots. In: <i>Proceedings of the 13th European Conference on Artificial Life</i>. MIT Press; 2015:78. doi:<a href=\"https://doi.org/10.7551/978-0-262-33027-5-ch018\">10.7551/978-0-262-33027-5-ch018</a>","mla":"Martius, Georg S., and Eckehard Olbrich. “Quantifying Self-Organizing Behavior of Autonomous Robots.” <i>Proceedings of the 13th European Conference on Artificial Life</i>, MIT Press, 2015, p. 78, doi:<a href=\"https://doi.org/10.7551/978-0-262-33027-5-ch018\">10.7551/978-0-262-33027-5-ch018</a>.","apa":"Martius, G. S., &#38; Olbrich, E. (2015). Quantifying self-organizing behavior of autonomous robots. In <i>Proceedings of the 13th European Conference on Artificial Life</i> (p. 78). York, United Kingdom: MIT Press. <a href=\"https://doi.org/10.7551/978-0-262-33027-5-ch018\">https://doi.org/10.7551/978-0-262-33027-5-ch018</a>"},"oa_version":"Published Version","date_created":"2023-04-30T22:01:07Z","month":"07","quality_controlled":"1","acknowledgement":"This work was supported by the DFG (SPP 1527) and the EU (FP7, REA grant no 291734).","doi":"10.7551/978-0-262-33027-5-ch018","date_published":"2015-07-01T00:00:00Z","status":"public","day":"01","oa":1},{"tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","short":"CC BY-NC (4.0)"},"issue":"4","scopus_import":"1","year":"2015","has_accepted_license":"1","volume":1,"abstract":[{"text":"Motility is a basic feature of living microorganisms, and how it works is often determined by environmental cues. Recent efforts have focused on developing artificial systems that can mimic microorganisms, in particular their self-propulsion. We report on the design and characterization of synthetic self-propelled particles that migrate upstream, known as positive rheotaxis. This phenomenon results from a purely physical mechanism involving the interplay between the polarity of the particles and their alignment by a viscous torque. We show quantitative agreement between experimental data and a simple model of an overdamped Brownian pendulum. The model notably predicts the existence of a stagnation point in a diverging flow. We take advantage of this property to demonstrate that our active particles can sense and predictably organize in an imposed flow. Our colloidal system represents an important step toward the realization of biomimetic microsystems with the ability to sense and respond to environmental changes.","lang":"eng"}],"user_id":"D865714E-FA4E-11E9-B85B-F5C5E5697425","article_processing_charge":"No","file":[{"content_type":"application/pdf","access_level":"open_access","creator":"cziletti","file_id":"9058","relation":"main_file","file_size":2416780,"date_created":"2021-02-02T13:22:19Z","success":1,"file_name":"2015_ScienceAdvances_Palacci.pdf","date_updated":"2021-02-02T13:22:19Z","checksum":"b97d62433581875c1b85210c5f6ae370"}],"date_updated":"2023-02-23T13:47:52Z","author":[{"full_name":"Palacci, Jérémie A","last_name":"Palacci","id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d","first_name":"Jérémie A","orcid":"0000-0002-7253-9465"},{"first_name":"Stefano","last_name":"Sacanna","full_name":"Sacanna, Stefano"},{"full_name":"Abramian, Anaïs","last_name":"Abramian","first_name":"Anaïs"},{"first_name":"Jérémie","full_name":"Barral, Jérémie","last_name":"Barral"},{"last_name":"Hanson","full_name":"Hanson, Kasey","first_name":"Kasey"},{"full_name":"Grosberg, Alexander Y.","last_name":"Grosberg","first_name":"Alexander Y."},{"full_name":"Pine, David J.","last_name":"Pine","first_name":"David J."},{"full_name":"Chaikin, Paul M.","last_name":"Chaikin","first_name":"Paul M."}],"publication_identifier":{"issn":["2375-2548"]},"pmid":1,"language":[{"iso":"eng"}],"ddc":["530"],"publication_status":"published","file_date_updated":"2021-02-02T13:22:19Z","_id":"9057","publisher":"American Association for the Advancement of Science ","article_type":"original","title":"Artificial rheotaxis","oa_version":"Published Version","citation":{"ama":"Palacci JA, Sacanna S, Abramian A, et al. Artificial rheotaxis. <i>Science Advances</i>. 2015;1(4). doi:<a href=\"https://doi.org/10.1126/sciadv.1400214\">10.1126/sciadv.1400214</a>","mla":"Palacci, Jérémie A., et al. “Artificial Rheotaxis.” <i>Science Advances</i>, vol. 1, no. 4, e1400214, American Association for the Advancement of Science , 2015, doi:<a href=\"https://doi.org/10.1126/sciadv.1400214\">10.1126/sciadv.1400214</a>.","apa":"Palacci, J. A., Sacanna, S., Abramian, A., Barral, J., Hanson, K., Grosberg, A. Y., … Chaikin, P. M. (2015). Artificial rheotaxis. <i>Science Advances</i>. American Association for the Advancement of Science . <a href=\"https://doi.org/10.1126/sciadv.1400214\">https://doi.org/10.1126/sciadv.1400214</a>","short":"J.A. Palacci, S. Sacanna, A. Abramian, J. Barral, K. Hanson, A.Y. Grosberg, D.J. Pine, P.M. Chaikin, Science Advances 1 (2015).","ieee":"J. A. Palacci <i>et al.</i>, “Artificial rheotaxis,” <i>Science Advances</i>, vol. 1, no. 4. American Association for the Advancement of Science , 2015.","chicago":"Palacci, Jérémie A, Stefano Sacanna, Anaïs Abramian, Jérémie Barral, Kasey Hanson, Alexander Y. Grosberg, David J. Pine, and Paul M. Chaikin. “Artificial Rheotaxis.” <i>Science Advances</i>. American Association for the Advancement of Science , 2015. <a href=\"https://doi.org/10.1126/sciadv.1400214\">https://doi.org/10.1126/sciadv.1400214</a>.","ista":"Palacci JA, Sacanna S, Abramian A, Barral J, Hanson K, Grosberg AY, Pine DJ, Chaikin PM. 2015. Artificial rheotaxis. Science Advances. 1(4), e1400214."},"date_created":"2021-02-02T13:15:02Z","publication":"Science Advances","type":"journal_article","license":"https://creativecommons.org/licenses/by-nc/4.0/","quality_controlled":"1","month":"05","arxiv":1,"status":"public","article_number":"e1400214","date_published":"2015-05-01T00:00:00Z","doi":"10.1126/sciadv.1400214","intvolume":"         1","oa":1,"external_id":{"pmid":["26601175"],"arxiv":["1505.05111"]},"extern":"1","day":"01"},{"quality_controlled":"1","month":"06","date_created":"2021-02-15T14:21:49Z","citation":{"ama":"Lefauve A, Muller CJ, Melet A. A three-dimensional map of tidal dissipation over abyssal hills. <i>Journal of Geophysical Research: Oceans</i>. 2015;120(7):4760-4777. doi:<a href=\"https://doi.org/10.1002/2014jc010598\">10.1002/2014jc010598</a>","apa":"Lefauve, A., Muller, C. J., &#38; Melet, A. (2015). A three-dimensional map of tidal dissipation over abyssal hills. <i>Journal of Geophysical Research: Oceans</i>. American Geophysical Union. <a href=\"https://doi.org/10.1002/2014jc010598\">https://doi.org/10.1002/2014jc010598</a>","mla":"Lefauve, Adrien, et al. “A Three-Dimensional Map of Tidal Dissipation over Abyssal Hills.” <i>Journal of Geophysical Research: Oceans</i>, vol. 120, no. 7, American Geophysical Union, 2015, pp. 4760–77, doi:<a href=\"https://doi.org/10.1002/2014jc010598\">10.1002/2014jc010598</a>.","short":"A. Lefauve, C.J. Muller, A. Melet, Journal of Geophysical Research: Oceans 120 (2015) 4760–4777.","ieee":"A. Lefauve, C. J. Muller, and A. Melet, “A three-dimensional map of tidal dissipation over abyssal hills,” <i>Journal of Geophysical Research: Oceans</i>, vol. 120, no. 7. American Geophysical Union, pp. 4760–4777, 2015.","chicago":"Lefauve, Adrien, Caroline J Muller, and Angélique Melet. “A Three-Dimensional Map of Tidal Dissipation over Abyssal Hills.” <i>Journal of Geophysical Research: Oceans</i>. American Geophysical Union, 2015. <a href=\"https://doi.org/10.1002/2014jc010598\">https://doi.org/10.1002/2014jc010598</a>.","ista":"Lefauve A, Muller CJ, Melet A. 2015. A three-dimensional map of tidal dissipation over abyssal hills. Journal of Geophysical Research: Oceans. 120(7), 4760–4777."},"oa_version":"Published Version","publication":"Journal of Geophysical Research: Oceans","type":"journal_article","oa":1,"day":"08","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1002/2014JC010598"}],"extern":"1","status":"public","intvolume":"       120","doi":"10.1002/2014jc010598","date_published":"2015-06-08T00:00:00Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","abstract":[{"text":"The breaking of internal tides is believed to provide a large part of the power needed to mix the abyssal ocean and sustain the meridional overturning circulation. Both the fraction of internal tide energy that is dissipated locally and the resulting vertical mixing distribution are crucial for the ocean state, but remain poorly quantified. Here we present a first worldwide estimate of mixing due to internal tides generated at small‐scale abyssal hills. Our estimate is based on linear wave theory, a nonlinear parameterization for wave breaking and uses quasi‐global small‐scale abyssal hill bathymetry, stratification, and tidal data. We show that a large fraction of abyssal‐hill generated internal tide energy is locally dissipated over mid‐ocean ridges in the Southern Hemisphere. Significant dissipation occurs above ridge crests, and, upon rescaling by the local stratification, follows a monotonic exponential decay with height off the bottom, with a nonuniform decay scale. We however show that a substantial part of the dissipation occurs over the smoother flanks of mid‐ocean ridges, and exhibits a middepth maximum due to the interplay of wave amplitude with stratification. We link the three‐dimensional map of dissipation to abyssal hills characteristics, ocean stratification, and tidal forcing, and discuss its potential implementation in time‐evolving parameterizations for global climate models. Current tidal parameterizations only account for waves generated at large‐scale satellite‐resolved bathymetry. Our results suggest that the presence of small‐scale, mostly unresolved abyssal hills could significantly enhance the spatial inhomogeneity of tidal mixing, particularly above mid‐ocean ridges in the Southern Hemisphere.","lang":"eng"}],"date_updated":"2022-01-24T13:45:41Z","article_processing_charge":"No","author":[{"last_name":"Lefauve","full_name":"Lefauve, Adrien","first_name":"Adrien"},{"orcid":"0000-0001-5836-5350","full_name":"Muller, Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","last_name":"Muller","first_name":"Caroline J"},{"first_name":"Angélique","last_name":"Melet","full_name":"Melet, Angélique"}],"publication_identifier":{"issn":["2169-9275"]},"language":[{"iso":"eng"}],"year":"2015","issue":"7","volume":120,"title":"A three-dimensional map of tidal dissipation over abyssal hills","page":"4760-4777","publication_status":"published","_id":"9141","article_type":"original","publisher":"American Geophysical Union"},{"year":"2015","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"volume":4,"has_accepted_license":"1","file":[{"checksum":"1e4024b3161adcae4a53a0b3dc8a946e","file_name":"2015_eLife_Sehring.pdf","date_updated":"2020-07-14T12:48:15Z","file_id":"5769","relation":"main_file","content_type":"application/pdf","access_level":"open_access","creator":"dernst","file_size":7202224,"date_created":"2018-12-20T15:50:56Z"}],"date_updated":"2021-01-12T08:21:58Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"The actomyosin cytoskeleton is a primary force-generating mechanism in morphogenesis, thus a robust spatial control of cytoskeletal positioning is essential. In this report, we demonstrate that actomyosin contractility and planar cell polarity (PCP) interact in post-mitotic Ciona notochord cells to self-assemble and reposition actomyosin rings, which play an essential role for cell elongation. Intriguingly, rings always form at the cells′ anterior edge before migrating towards the center as contractility increases, reflecting a novel dynamical property of the cortex. Our drug and genetic manipulations uncover a tug-of-war between contractility, which localizes cortical flows toward the equator and PCP, which tries to reposition them. We develop a simple model of the physical forces underlying this tug-of-war, which quantitatively reproduces our results. We thus propose a quantitative framework for dissecting the relative contribution of contractility and PCP to the self-assembly and repositioning of cytoskeletal structures, which should be applicable to other morphogenetic events.","lang":"eng"}],"language":[{"iso":"eng"}],"author":[{"full_name":"Sehring, Ivonne","last_name":"Sehring","first_name":"Ivonne"},{"first_name":"Pierre","last_name":"Recho","full_name":"Recho, Pierre"},{"last_name":"Denker","full_name":"Denker, Elsa","first_name":"Elsa"},{"first_name":"Matthew","full_name":"Kourakis, Matthew","last_name":"Kourakis"},{"first_name":"Birthe","full_name":"Mathiesen, Birthe","last_name":"Mathiesen"},{"first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B","last_name":"Hannezo","orcid":"0000-0001-6005-1561"},{"first_name":"Bo","last_name":"Dong","full_name":"Dong, Bo"},{"last_name":"Jiang","full_name":"Jiang, Di","first_name":"Di"}],"file_date_updated":"2020-07-14T12:48:15Z","publication_status":"published","ddc":["539","570"],"publist_id":"6512","publisher":"eLife Sciences Publications","_id":"928","title":"Assembly and positioning of actomyosin rings by contractility and planar cell polarity","publication":"eLife","date_created":"2018-12-11T11:49:15Z","citation":{"ista":"Sehring I, Recho P, Denker E, Kourakis M, Mathiesen B, Hannezo EB, Dong B, Jiang D. 2015. Assembly and positioning of actomyosin rings by contractility and planar cell polarity. eLife. 4, e09206.","chicago":"Sehring, Ivonne, Pierre Recho, Elsa Denker, Matthew Kourakis, Birthe Mathiesen, Edouard B Hannezo, Bo Dong, and Di Jiang. “Assembly and Positioning of Actomyosin Rings by Contractility and Planar Cell Polarity.” <i>ELife</i>. eLife Sciences Publications, 2015. <a href=\"https://doi.org/10.7554/eLife.09206\">https://doi.org/10.7554/eLife.09206</a>.","short":"I. Sehring, P. Recho, E. Denker, M. Kourakis, B. Mathiesen, E.B. Hannezo, B. Dong, D. Jiang, ELife 4 (2015).","ieee":"I. Sehring <i>et al.</i>, “Assembly and positioning of actomyosin rings by contractility and planar cell polarity,” <i>eLife</i>, vol. 4. eLife Sciences Publications, 2015.","apa":"Sehring, I., Recho, P., Denker, E., Kourakis, M., Mathiesen, B., Hannezo, E. B., … Jiang, D. (2015). Assembly and positioning of actomyosin rings by contractility and planar cell polarity. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.09206\">https://doi.org/10.7554/eLife.09206</a>","mla":"Sehring, Ivonne, et al. “Assembly and Positioning of Actomyosin Rings by Contractility and Planar Cell Polarity.” <i>ELife</i>, vol. 4, e09206, eLife Sciences Publications, 2015, doi:<a href=\"https://doi.org/10.7554/eLife.09206\">10.7554/eLife.09206</a>.","ama":"Sehring I, Recho P, Denker E, et al. Assembly and positioning of actomyosin rings by contractility and planar cell polarity. <i>eLife</i>. 2015;4. doi:<a href=\"https://doi.org/10.7554/eLife.09206\">10.7554/eLife.09206</a>"},"oa_version":"Published Version","type":"journal_article","quality_controlled":"1","month":"10","status":"public","intvolume":"         4","date_published":"2015-10-21T00:00:00Z","doi":"10.7554/eLife.09206","article_number":"e09206","day":"21","extern":"1","oa":1}]