[{"acknowledgement":"We are deeply grateful to the late Gregor Högenauer who built the foundation for this study with his visionary work on the inhibitor diazaborine and its bacterial target. We thank Rolf Breinbauer for insightful discussions on boron chemistry. We thank Anton Meinhart and Tim Clausen for the valuable discussion of the manuscript. We are indebted to Thomas Köcher for the MS measurement of the diazaborine-ATPγS adduct. We thank the team of the VBCF for support during early phases of this work and the IST Austria Electron Microscopy Facility for providing equipment. The lab of D.H. is supported by Boehringer Ingelheim. The work was funded by FWF projects P32536 and P32977 (to H.B.).","quality_controlled":"1","doi":"10.1038/s41467-021-23854-x","citation":{"ama":"Prattes M, Grishkovskaya I, Hodirnau V-V, et al. Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-23854-x\">10.1038/s41467-021-23854-x</a>","short":"M. Prattes, I. Grishkovskaya, V.-V. Hodirnau, I. Rössler, I. Klein, C. Hetzmannseder, G. Zisser, C.C. Gruber, K. Gruber, D. Haselbach, H. Bergler, Nature Communications 12 (2021).","chicago":"Prattes, Michael, Irina Grishkovskaya, Victor-Valentin Hodirnau, Ingrid Rössler, Isabella Klein, Christina Hetzmannseder, Gertrude Zisser, et al. “Structural Basis for Inhibition of the AAA-ATPase Drg1 by Diazaborine.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23854-x\">https://doi.org/10.1038/s41467-021-23854-x</a>.","apa":"Prattes, M., Grishkovskaya, I., Hodirnau, V.-V., Rössler, I., Klein, I., Hetzmannseder, C., … Bergler, H. (2021). Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-23854-x\">https://doi.org/10.1038/s41467-021-23854-x</a>","mla":"Prattes, Michael, et al. “Structural Basis for Inhibition of the AAA-ATPase Drg1 by Diazaborine.” <i>Nature Communications</i>, vol. 12, no. 1, 3483, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23854-x\">10.1038/s41467-021-23854-x</a>.","ieee":"M. Prattes <i>et al.</i>, “Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine,” <i>Nature Communications</i>, vol. 12, no. 1. Springer Nature, 2021.","ista":"Prattes M, Grishkovskaya I, Hodirnau V-V, Rössler I, Klein I, Hetzmannseder C, Zisser G, Gruber CC, Gruber K, Haselbach D, Bergler H. 2021. Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. Nature Communications. 12(1), 3483."},"intvolume":"        12","pmid":1,"has_accepted_license":"1","publication_identifier":{"eissn":["2041-1723"]},"language":[{"iso":"eng"}],"year":"2021","external_id":{"pmid":["34108481"],"isi":["000664874700014"]},"license":"https://creativecommons.org/licenses/by/4.0/","isi":1,"file":[{"date_updated":"2021-06-15T18:55:59Z","creator":"cziletti","checksum":"40fc24c1310930990b52a8ad1142ee97","file_size":3397292,"file_name":"2021_NatureComm_Prattes.pdf","relation":"main_file","content_type":"application/pdf","success":1,"date_created":"2021-06-15T18:55:59Z","access_level":"open_access","file_id":"9556"}],"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"abstract":[{"lang":"eng","text":"The hexameric AAA-ATPase Drg1 is a key factor in eukaryotic ribosome biogenesis and initiates cytoplasmic maturation of the large ribosomal subunit by releasing the shuttling maturation factor Rlp24. Drg1 monomers contain two AAA-domains (D1 and D2) that act in a concerted manner. Rlp24 release is inhibited by the drug diazaborine which blocks ATP hydrolysis in D2. The mode of inhibition was unknown. Here we show the first cryo-EM structure of Drg1 revealing the inhibitory mechanism. Diazaborine forms a covalent bond to the 2′-OH of the nucleotide in D2, explaining its specificity for this site. As a consequence, the D2 domain is locked in a rigid, inactive state, stalling the whole Drg1 hexamer. Resistance mechanisms identified include abolished drug binding and altered positioning of the nucleotide. Our results suggest nucleotide-modifying compounds as potential novel inhibitors for AAA-ATPases."}],"oa":1,"ddc":["570"],"department":[{"_id":"EM-Fac"}],"author":[{"full_name":"Prattes, Michael","last_name":"Prattes","first_name":"Michael"},{"full_name":"Grishkovskaya, Irina","first_name":"Irina","last_name":"Grishkovskaya"},{"full_name":"Hodirnau, Victor-Valentin","id":"3661B498-F248-11E8-B48F-1D18A9856A87","first_name":"Victor-Valentin","last_name":"Hodirnau"},{"full_name":"Rössler, Ingrid","first_name":"Ingrid","last_name":"Rössler"},{"first_name":"Isabella","last_name":"Klein","full_name":"Klein, Isabella"},{"full_name":"Hetzmannseder, Christina","first_name":"Christina","last_name":"Hetzmannseder"},{"full_name":"Zisser, Gertrude","first_name":"Gertrude","last_name":"Zisser"},{"first_name":"Christian C.","last_name":"Gruber","full_name":"Gruber, Christian C."},{"full_name":"Gruber, Karl","last_name":"Gruber","first_name":"Karl"},{"first_name":"David","last_name":"Haselbach","full_name":"Haselbach, David"},{"first_name":"Helmut","last_name":"Bergler","full_name":"Bergler, Helmut"}],"acknowledged_ssus":[{"_id":"EM-Fac"}],"file_date_updated":"2021-06-15T18:55:59Z","publication":"Nature Communications","article_processing_charge":"No","_id":"9540","type":"journal_article","issue":"1","oa_version":"Published Version","date_created":"2021-06-10T14:57:45Z","status":"public","article_number":"3483","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine","volume":12,"day":"09","date_updated":"2023-08-08T14:05:26Z","publisher":"Springer Nature","publication_status":"published","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_type":"original","date_published":"2021-06-09T00:00:00Z","month":"06"},{"external_id":{"isi":["000655481800014"]},"isi":1,"file":[{"date_updated":"2021-12-17T11:34:50Z","creator":"kschuh","checksum":"6036a8cdae95e1707c2a04d54e325ff4","file_size":3108845,"relation":"main_file","file_name":"2021_NatureCommunications_Vandael.pdf","content_type":"application/pdf","success":1,"date_created":"2021-12-17T11:34:50Z","access_level":"open_access","file_id":"10563"}],"ddc":["570"],"oa":1,"keyword":["general physics and astronomy","general biochemistry","genetics and molecular biology","general chemistry"],"abstract":[{"lang":"eng","text":"The hippocampal mossy fiber synapse is a key synapse of the trisynaptic circuit. Post-tetanic potentiation (PTP) is the most powerful form of plasticity at this synaptic connection. It is widely believed that mossy fiber PTP is an entirely presynaptic phenomenon, implying that PTP induction is input-specific, and requires neither activity of multiple inputs nor stimulation of postsynaptic neurons. To directly test cooperativity and associativity, we made paired recordings between single mossy fiber terminals and postsynaptic CA3 pyramidal neurons in rat brain slices. By stimulating non-overlapping mossy fiber inputs converging onto single CA3 neurons, we confirm that PTP is input-specific and non-cooperative. Unexpectedly, mossy fiber PTP exhibits anti-associative induction properties. EPSCs show only minimal PTP after combined pre- and postsynaptic high-frequency stimulation with intact postsynaptic Ca2+ signaling, but marked PTP in the absence of postsynaptic spiking and after suppression of postsynaptic Ca2+ signaling (10 mM EGTA). PTP is largely recovered by inhibitors of voltage-gated R- and L-type Ca2+ channels, group II mGluRs, and vacuolar-type H+-ATPase, suggesting the involvement of retrograde vesicular glutamate signaling. Transsynaptic regulation of PTP extends the repertoire of synaptic computations, implementing a brake on mossy fiber detonation and a “smart teacher” function of hippocampal mossy fiber synapses."}],"doi":"10.1038/s41467-021-23153-5","citation":{"short":"D.H. Vandael, Y. Okamoto, P.M. Jonas, Nature Communications 12 (2021).","chicago":"Vandael, David H, Yuji Okamoto, and Peter M Jonas. “Transsynaptic Modulation of Presynaptic Short-Term Plasticity in Hippocampal Mossy Fiber Synapses.” <i>Nature Communications</i>. Springer, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23153-5\">https://doi.org/10.1038/s41467-021-23153-5</a>.","apa":"Vandael, D. H., Okamoto, Y., &#38; Jonas, P. M. (2021). Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. <i>Nature Communications</i>. Springer. <a href=\"https://doi.org/10.1038/s41467-021-23153-5\">https://doi.org/10.1038/s41467-021-23153-5</a>","mla":"Vandael, David H., et al. “Transsynaptic Modulation of Presynaptic Short-Term Plasticity in Hippocampal Mossy Fiber Synapses.” <i>Nature Communications</i>, vol. 12, no. 1, 2912, Springer, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23153-5\">10.1038/s41467-021-23153-5</a>.","ieee":"D. H. Vandael, Y. Okamoto, and P. M. Jonas, “Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses,” <i>Nature Communications</i>, vol. 12, no. 1. Springer, 2021.","ista":"Vandael DH, Okamoto Y, Jonas PM. 2021. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. Nature Communications. 12(1), 2912.","ama":"Vandael DH, Okamoto Y, Jonas PM. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-23153-5\">10.1038/s41467-021-23153-5</a>"},"quality_controlled":"1","ec_funded":1,"acknowledgement":"We thank Drs. Carolina Borges-Merjane and Jose Guzman for critically reading the manuscript, and Pablo Castillo for discussions. We are grateful to Alois Schlögl for help with analysis, Florian Marr for excellent technical assistance and cell reconstruction, Christina Altmutter for technical help, Eleftheria Kralli-Beller for manuscript editing, and the Scientific Service Units of IST Austria for support. This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No 692692) and the Fond zur Förderung der Wissenschaftlichen Forschung (Z 312-B27, Wittgenstein award), both to P.J.","related_material":{"link":[{"relation":"press_release","description":"News on IST Homepage","url":"https://ist.ac.at/en/news/synaptic-transmission-not-a-one-way-street/"}]},"language":[{"iso":"eng"}],"publication_identifier":{"issn":["2041-1723"]},"year":"2021","intvolume":"        12","has_accepted_license":"1","scopus_import":"1","date_published":"2021-05-18T00:00:00Z","month":"05","article_type":"original","publisher":"Springer","date_updated":"2023-08-10T14:16:16Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publication_status":"published","_id":"9778","type":"journal_article","article_processing_charge":"No","issue":"1","publication":"Nature Communications","file_date_updated":"2021-12-17T11:34:50Z","project":[{"name":"Biophysics and circuit function of a giant cortical glumatergic synapse","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","grant_number":"692692","call_identifier":"H2020"},{"call_identifier":"FWF","grant_number":"Z00312","name":"The Wittgenstein Prize","_id":"25C5A090-B435-11E9-9278-68D0E5697425"}],"date_created":"2021-08-06T07:22:55Z","oa_version":"Published Version","department":[{"_id":"PeJo"}],"acknowledged_ssus":[{"_id":"SSU"}],"author":[{"id":"3AE48E0A-F248-11E8-B48F-1D18A9856A87","first_name":"David H","last_name":"Vandael","orcid":"0000-0001-7577-1676","full_name":"Vandael, David H"},{"orcid":"0000-0003-0408-6094","full_name":"Okamoto, Yuji","last_name":"Okamoto","first_name":"Yuji","id":"3337E116-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","last_name":"Jonas"}],"day":"18","article_number":"2912","status":"public","title":"Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"volume":12},{"department":[{"_id":"GradSch"},{"_id":"RoSe"}],"author":[{"id":"e1a2682f-dc8d-11ea-abe3-81da9ac728f1","first_name":"Asbjørn Bækgaard","last_name":"Lauritsen","orcid":"0000-0003-4476-2288","full_name":"Lauritsen, Asbjørn Bækgaard"}],"publication":"Journal of Mathematical Physics","file_date_updated":"2021-10-27T12:57:06Z","article_processing_charge":"No","_id":"9891","type":"journal_article","issue":"8","oa_version":"Published Version","date_created":"2021-08-12T07:08:36Z","status":"public","article_number":"083305","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Floating Wigner crystal and periodic jellium configurations","volume":62,"day":"01","scopus_import":"1","date_updated":"2023-08-11T10:29:48Z","publisher":"AIP Publishing","publication_status":"published","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_type":"original","date_published":"2021-08-01T00:00:00Z","month":"08","acknowledgement":"The author would like to thank Robert Seiringer for guidance and many helpful comments on this project. The author would also like to thank Mathieu Lewin for his comments on the manuscript and Lorenzo Portinale for providing his lecture notes for the course “Mathematics of quantum many-body systems” in spring 2020, taught by Robert Seiringer. The Proof of Theorem III.1 is inspired by these lecture notes.","quality_controlled":"1","doi":"10.1063/5.0053494","citation":{"ama":"Lauritsen AB. Floating Wigner crystal and periodic jellium configurations. <i>Journal of Mathematical Physics</i>. 2021;62(8). doi:<a href=\"https://doi.org/10.1063/5.0053494\">10.1063/5.0053494</a>","apa":"Lauritsen, A. B. (2021). Floating Wigner crystal and periodic jellium configurations. <i>Journal of Mathematical Physics</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0053494\">https://doi.org/10.1063/5.0053494</a>","short":"A.B. Lauritsen, Journal of Mathematical Physics 62 (2021).","chicago":"Lauritsen, Asbjørn Bækgaard. “Floating Wigner Crystal and Periodic Jellium Configurations.” <i>Journal of Mathematical Physics</i>. AIP Publishing, 2021. <a href=\"https://doi.org/10.1063/5.0053494\">https://doi.org/10.1063/5.0053494</a>.","ieee":"A. B. Lauritsen, “Floating Wigner crystal and periodic jellium configurations,” <i>Journal of Mathematical Physics</i>, vol. 62, no. 8. AIP Publishing, 2021.","ista":"Lauritsen AB. 2021. Floating Wigner crystal and periodic jellium configurations. Journal of Mathematical Physics. 62(8), 083305.","mla":"Lauritsen, Asbjørn Bækgaard. “Floating Wigner Crystal and Periodic Jellium Configurations.” <i>Journal of Mathematical Physics</i>, vol. 62, no. 8, 083305, AIP Publishing, 2021, doi:<a href=\"https://doi.org/10.1063/5.0053494\">10.1063/5.0053494</a>."},"intvolume":"        62","arxiv":1,"has_accepted_license":"1","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0022-2488"],"eissn":["1089-7658"]},"year":"2021","external_id":{"isi":["000683960800003"],"arxiv":["2103.07975"]},"isi":1,"file":[{"file_id":"10188","access_level":"open_access","date_created":"2021-10-27T12:57:06Z","success":1,"content_type":"application/pdf","file_name":"2021_JMathPhy_Lauritsen.pdf","relation":"main_file","file_size":4352640,"checksum":"d035be2b894c4d50d90ac5ce252e27cd","creator":"cziletti","date_updated":"2021-10-27T12:57:06Z"}],"keyword":["Mathematical Physics","Statistical and Nonlinear Physics"],"abstract":[{"lang":"eng","text":"Extending on ideas of Lewin, Lieb, and Seiringer [Phys. Rev. B 100, 035127 (2019)], we present a modified “floating crystal” trial state for jellium (also known as the classical homogeneous electron gas) with density equal to a characteristic function. This allows us to show that three definitions of the jellium energy coincide in dimensions d ≥ 2, thus extending the result of Cotar and Petrache [“Equality of the Jellium and uniform electron gas next-order asymptotic terms for Coulomb and Riesz potentials,” arXiv: 1707.07664 (2019)] and Lewin, Lieb, and Seiringer [Phys. Rev. B 100, 035127 (2019)] that the three definitions coincide in dimension d ≥ 3. We show that the jellium energy is also equivalent to a “renormalized energy” studied in a series of papers by Serfaty and others, and thus, by the work of Bétermin and Sandier [Constr. Approximation 47, 39–74 (2018)], we relate the jellium energy to the order n term in the logarithmic energy of n points on the unit 2-sphere. We improve upon known lower bounds for this renormalized energy. Additionally, we derive formulas for the jellium energy of periodic configurations."}],"ddc":["530"],"oa":1},{"quality_controlled":"1","ec_funded":1,"citation":{"ama":"Peruzzo M, Hassani F, Szep G, et al. Geometric superinductance qubits: Controlling phase delocalization across a single Josephson junction. <i>PRX Quantum</i>. 2021;2(4):040341. doi:<a href=\"https://doi.org/10.1103/PRXQuantum.2.040341\">10.1103/PRXQuantum.2.040341</a>","ista":"Peruzzo M, Hassani F, Szep G, Trioni A, Redchenko E, Zemlicka M, Fink JM. 2021. Geometric superinductance qubits: Controlling phase delocalization across a single Josephson junction. PRX Quantum. 2(4), 040341.","ieee":"M. Peruzzo <i>et al.</i>, “Geometric superinductance qubits: Controlling phase delocalization across a single Josephson junction,” <i>PRX Quantum</i>, vol. 2, no. 4. American Physical Society, p. 040341, 2021.","mla":"Peruzzo, Matilda, et al. “Geometric Superinductance Qubits: Controlling Phase Delocalization across a Single Josephson Junction.” <i>PRX Quantum</i>, vol. 2, no. 4, American Physical Society, 2021, p. 040341, doi:<a href=\"https://doi.org/10.1103/PRXQuantum.2.040341\">10.1103/PRXQuantum.2.040341</a>.","apa":"Peruzzo, M., Hassani, F., Szep, G., Trioni, A., Redchenko, E., Zemlicka, M., &#38; Fink, J. M. (2021). Geometric superinductance qubits: Controlling phase delocalization across a single Josephson junction. <i>PRX Quantum</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PRXQuantum.2.040341\">https://doi.org/10.1103/PRXQuantum.2.040341</a>","short":"M. Peruzzo, F. Hassani, G. Szep, A. Trioni, E. Redchenko, M. Zemlicka, J.M. Fink, PRX Quantum 2 (2021) 040341.","chicago":"Peruzzo, Matilda, Farid Hassani, Gregory Szep, Andrea Trioni, Elena Redchenko, Martin Zemlicka, and Johannes M Fink. “Geometric Superinductance Qubits: Controlling Phase Delocalization across a Single Josephson Junction.” <i>PRX Quantum</i>. American Physical Society, 2021. <a href=\"https://doi.org/10.1103/PRXQuantum.2.040341\">https://doi.org/10.1103/PRXQuantum.2.040341</a>."},"doi":"10.1103/PRXQuantum.2.040341","related_material":{"record":[{"relation":"research_data","status":"public","id":"13057"},{"relation":"dissertation_contains","status":"public","id":"9920"}]},"acknowledgement":"We thank W. Hughes for analytic and numerical modeling during the early stages of this work, J. Koch for discussions and support with the scqubits package, R. Sett, P. Zielinski, and L. Drmic for software development, and G. Katsaros for equipment support, as well as the MIBA workshop and the Institute of Science and Technology Austria nanofabrication facility. We thank I. Pop, S. Deleglise, and E. Flurin for discussions. This work was supported by a NOMIS Foundation research grant, the Austrian Science Fund (FWF) through BeyondC (F7105), and IST Austria. M.P. is the recipient of a Pöttinger scholarship at IST Austria. E.R. is the recipient of a DOC fellowship of the Austrian Academy of Sciences at IST Austria.","year":"2021","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["2691-3399"]},"has_accepted_license":"1","intvolume":"         2","arxiv":1,"isi":1,"page":"040341","external_id":{"isi":["000723015100001"],"arxiv":["2106.05882"]},"keyword":["quantum physics","mesoscale and nanoscale physics"],"abstract":[{"text":"There are two elementary superconducting qubit types that derive directly from the quantum harmonic oscillator. In one, the inductor is replaced by a nonlinear Josephson junction to realize the widely used charge qubits with a compact phase variable and a discrete charge wave function. In the other, the junction is added in parallel, which gives rise to an extended phase variable, continuous wave functions, and a rich energy-level structure due to the loop topology. While the corresponding rf superconducting quantum interference device Hamiltonian was introduced as a quadratic quasi-one-dimensional potential approximation to describe the fluxonium qubit implemented with long Josephson-junction arrays, in this work we implement it directly using a linear superinductor formed by a single uninterrupted aluminum wire. We present a large variety of qubits, all stemming from the same circuit but with drastically different characteristic energy scales. This includes flux and fluxonium qubits but also the recently introduced quasicharge qubit with strongly enhanced zero-point phase fluctuations and a heavily suppressed flux dispersion. The use of a geometric inductor results in high reproducibility of the inductive energy as guaranteed by top-down lithography—a key ingredient for intrinsically protected superconducting qubits.","lang":"eng"}],"ddc":["530"],"oa":1,"file":[{"access_level":"open_access","date_created":"2022-01-18T11:29:33Z","file_id":"10641","relation":"main_file","file_name":"2021_PRXQuantum_Peruzzo.pdf","content_type":"application/pdf","success":1,"creator":"cchlebak","checksum":"36eb41ea43d8ca22b0efab12419e4eb2","file_size":4247422,"date_updated":"2022-01-18T11:29:33Z"}],"oa_version":"Published Version","date_created":"2021-08-17T08:14:18Z","project":[{"grant_number":"F07105","call_identifier":"FWF","_id":"26927A52-B435-11E9-9278-68D0E5697425","name":"Integrating superconducting quantum circuits"},{"call_identifier":"H2020","grant_number":"665385","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","name":"International IST Doctoral Program"},{"name":"Hybrid Semiconductor - Superconductor Quantum Devices","_id":"2622978C-B435-11E9-9278-68D0E5697425"}],"publication":"PRX Quantum","file_date_updated":"2022-01-18T11:29:33Z","issue":"4","_id":"9928","type":"journal_article","article_processing_charge":"No","author":[{"first_name":"Matilda","id":"3F920B30-F248-11E8-B48F-1D18A9856A87","last_name":"Peruzzo","full_name":"Peruzzo, Matilda","orcid":"0000-0002-3415-4628"},{"first_name":"Farid","id":"2AED110C-F248-11E8-B48F-1D18A9856A87","last_name":"Hassani","orcid":"0000-0001-6937-5773","full_name":"Hassani, Farid"},{"last_name":"Szep","first_name":"Gregory","full_name":"Szep, Gregory"},{"first_name":"Andrea","id":"42F71B44-F248-11E8-B48F-1D18A9856A87","last_name":"Trioni","full_name":"Trioni, Andrea"},{"full_name":"Redchenko, Elena","id":"2C21D6E8-F248-11E8-B48F-1D18A9856A87","first_name":"Elena","last_name":"Redchenko"},{"last_name":"Zemlicka","first_name":"Martin","id":"2DCF8DE6-F248-11E8-B48F-1D18A9856A87","full_name":"Zemlicka, Martin"},{"full_name":"Fink, Johannes M","orcid":"0000-0001-8112-028X","last_name":"Fink","first_name":"Johannes M","id":"4B591CBA-F248-11E8-B48F-1D18A9856A87"}],"acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"M-Shop"}],"department":[{"_id":"JoFi"},{"_id":"NanoFab"},{"_id":"M-Shop"}],"day":"24","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"volume":2,"title":"Geometric superinductance qubits: Controlling phase delocalization across a single Josephson junction","status":"public","scopus_import":"1","article_type":"original","month":"11","date_published":"2021-11-24T00:00:00Z","publication_status":"published","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-09-07T13:31:22Z","publisher":"American Physical Society"},{"status":"public","title":"Complete gradient estimates of quantum Markov semigroups","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"volume":387,"day":"30","department":[{"_id":"JaMa"}],"author":[{"orcid":"0000-0002-0519-4241","full_name":"Wirth, Melchior","last_name":"Wirth","first_name":"Melchior","id":"88644358-0A0E-11EA-8FA5-49A33DDC885E"},{"last_name":"Zhang","id":"D8F41E38-9E66-11E9-A9E2-65C2E5697425","first_name":"Haonan","full_name":"Zhang, Haonan"}],"article_processing_charge":"Yes (via OA deal)","_id":"9973","type":"journal_article","file_date_updated":"2021-09-08T09:46:34Z","publication":"Communications in Mathematical Physics","project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"},{"call_identifier":"H2020","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"grant_number":"F6504","name":"Taming Complexity in Partial Differential Systems","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2"}],"oa_version":"Published Version","date_created":"2021-08-30T10:07:44Z","publisher":"Springer Nature","date_updated":"2023-08-11T11:09:07Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publication_status":"published","month":"08","date_published":"2021-08-30T00:00:00Z","article_type":"original","scopus_import":"1","intvolume":"       387","arxiv":1,"has_accepted_license":"1","publication_identifier":{"issn":["0010-3616"],"eissn":["1432-0916"]},"language":[{"iso":"eng"}],"year":"2021","acknowledgement":"Both authors would like to thank Jan Maas for fruitful discussions and helpful comments.","citation":{"ama":"Wirth M, Zhang H. Complete gradient estimates of quantum Markov semigroups. <i>Communications in Mathematical Physics</i>. 2021;387:761–791. doi:<a href=\"https://doi.org/10.1007/s00220-021-04199-4\">10.1007/s00220-021-04199-4</a>","apa":"Wirth, M., &#38; Zhang, H. (2021). Complete gradient estimates of quantum Markov semigroups. <i>Communications in Mathematical Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00220-021-04199-4\">https://doi.org/10.1007/s00220-021-04199-4</a>","short":"M. Wirth, H. Zhang, Communications in Mathematical Physics 387 (2021) 761–791.","chicago":"Wirth, Melchior, and Haonan Zhang. “Complete Gradient Estimates of Quantum Markov Semigroups.” <i>Communications in Mathematical Physics</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1007/s00220-021-04199-4\">https://doi.org/10.1007/s00220-021-04199-4</a>.","ieee":"M. Wirth and H. Zhang, “Complete gradient estimates of quantum Markov semigroups,” <i>Communications in Mathematical Physics</i>, vol. 387. Springer Nature, pp. 761–791, 2021.","ista":"Wirth M, Zhang H. 2021. Complete gradient estimates of quantum Markov semigroups. Communications in Mathematical Physics. 387, 761–791.","mla":"Wirth, Melchior, and Haonan Zhang. “Complete Gradient Estimates of Quantum Markov Semigroups.” <i>Communications in Mathematical Physics</i>, vol. 387, Springer Nature, 2021, pp. 761–791, doi:<a href=\"https://doi.org/10.1007/s00220-021-04199-4\">10.1007/s00220-021-04199-4</a>."},"doi":"10.1007/s00220-021-04199-4","quality_controlled":"1","ec_funded":1,"file":[{"file_size":505971,"checksum":"8a602f916b1c2b0dc1159708b7cb204b","creator":"cchlebak","date_updated":"2021-09-08T09:46:34Z","file_id":"9990","access_level":"open_access","date_created":"2021-09-08T07:34:24Z","content_type":"application/pdf","relation":"main_file","file_name":"2021_CommunMathPhys_Wirth.pdf"}],"oa":1,"ddc":["621"],"abstract":[{"lang":"eng","text":"In this article we introduce a complete gradient estimate for symmetric quantum Markov semigroups on von Neumann algebras equipped with a normal faithful tracial state, which implies semi-convexity of the entropy with respect to the recently introduced noncommutative 2-Wasserstein distance. We show that this complete gradient estimate is stable under tensor products and free products and establish its validity for a number of examples. As an application we prove a complete modified logarithmic Sobolev inequality with optimal constant for Poisson-type semigroups on free group factors."}],"keyword":["Mathematical Physics","Statistical and Nonlinear Physics"],"external_id":{"arxiv":["2007.13506"],"isi":["000691214200001"]},"isi":1,"page":"761–791"},{"isi":1,"external_id":{"isi":["000692534200001"],"arxiv":["2103.16468"]},"ddc":["519"],"oa":1,"abstract":[{"lang":"eng","text":"The numerical simulation of dynamical phenomena in interacting quantum systems is a notoriously hard problem. Although a number of promising numerical methods exist, they often have limited applicability due to the growth of entanglement or the presence of the so-called sign problem. In this work, we develop an importance sampling scheme for the simulation of quantum spin dynamics, building on a recent approach mapping quantum spin systems to classical stochastic processes. The importance sampling scheme is based on identifying the classical trajectory that yields the largest contribution to a given quantum observable. An exact transformation is then carried out to preferentially sample trajectories that are close to the dominant one. We demonstrate that this approach is capable of reducing the temporal growth of fluctuations in the stochastic quantities, thus extending the range of accessible times and system sizes compared to direct sampling. We discuss advantages and limitations of the proposed approach, outlining directions\r\nfor further developments."}],"keyword":["General Physics and Astronomy"],"file":[{"file_id":"9984","date_created":"2021-09-02T14:05:43Z","access_level":"open_access","success":1,"content_type":"application/pdf","relation":"main_file","file_name":"2021_SciPostPhys_DeNicola.pdf","checksum":"e4ec69d893e31811efc6093cb6ea8eb7","file_size":373833,"creator":"cchlebak","date_updated":"2021-09-02T14:05:43Z"}],"doi":"10.21468/scipostphys.11.3.048","citation":{"short":"S. De Nicola, SciPost Physics 11 (2021).","chicago":"De Nicola, Stefano. “Importance Sampling Scheme for the Stochastic Simulation of Quantum Spin Dynamics.” <i>SciPost Physics</i>. SciPost, 2021. <a href=\"https://doi.org/10.21468/scipostphys.11.3.048\">https://doi.org/10.21468/scipostphys.11.3.048</a>.","apa":"De Nicola, S. (2021). Importance sampling scheme for the stochastic simulation of quantum spin dynamics. <i>SciPost Physics</i>. SciPost. <a href=\"https://doi.org/10.21468/scipostphys.11.3.048\">https://doi.org/10.21468/scipostphys.11.3.048</a>","mla":"De Nicola, Stefano. “Importance Sampling Scheme for the Stochastic Simulation of Quantum Spin Dynamics.” <i>SciPost Physics</i>, vol. 11, no. 3, 048, SciPost, 2021, doi:<a href=\"https://doi.org/10.21468/scipostphys.11.3.048\">10.21468/scipostphys.11.3.048</a>.","ieee":"S. De Nicola, “Importance sampling scheme for the stochastic simulation of quantum spin dynamics,” <i>SciPost Physics</i>, vol. 11, no. 3. SciPost, 2021.","ista":"De Nicola S. 2021. Importance sampling scheme for the stochastic simulation of quantum spin dynamics. SciPost Physics. 11(3), 048.","ama":"De Nicola S. Importance sampling scheme for the stochastic simulation of quantum spin dynamics. <i>SciPost Physics</i>. 2021;11(3). doi:<a href=\"https://doi.org/10.21468/scipostphys.11.3.048\">10.21468/scipostphys.11.3.048</a>"},"quality_controlled":"1","ec_funded":1,"year":"2021","publication_identifier":{"eissn":["2666-9366"],"issn":["2542-4653"]},"language":[{"iso":"eng"}],"has_accepted_license":"1","arxiv":1,"intvolume":"        11","month":"09","date_published":"2021-09-02T00:00:00Z","article_type":"original","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publication_status":"published","publisher":"SciPost","date_updated":"2023-08-11T10:59:29Z","project":[{"name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","call_identifier":"H2020"}],"oa_version":"Published Version","date_created":"2021-09-02T11:49:47Z","article_processing_charge":"No","_id":"9981","issue":"3","type":"journal_article","publication":"SciPost Physics","file_date_updated":"2021-09-02T14:05:43Z","author":[{"last_name":"De Nicola","id":"42832B76-F248-11E8-B48F-1D18A9856A87","first_name":"Stefano","orcid":"0000-0002-4842-6671","full_name":"De Nicola, Stefano"}],"department":[{"_id":"MaSe"}],"day":"02","volume":11,"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Importance sampling scheme for the stochastic simulation of quantum spin dynamics","article_number":"048","status":"public"},{"acknowledgement":"This work was supported by the European Research Council (ERC) under the Euro-pean Union’s Horizon 2020 research and innovation programme (grant agreementNo. 694227).","ec_funded":1,"quality_controlled":"1","citation":{"ama":"Seiringer R. The polaron at strong coupling. <i>Reviews in Mathematical Physics</i>. 2021;33(01). doi:<a href=\"https://doi.org/10.1142/s0129055x20600120\">10.1142/s0129055x20600120</a>","chicago":"Seiringer, Robert. “The Polaron at Strong Coupling.” <i>Reviews in Mathematical Physics</i>. World Scientific Publishing, 2021. <a href=\"https://doi.org/10.1142/s0129055x20600120\">https://doi.org/10.1142/s0129055x20600120</a>.","short":"R. Seiringer, Reviews in Mathematical Physics 33 (2021).","apa":"Seiringer, R. (2021). The polaron at strong coupling. <i>Reviews in Mathematical Physics</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/s0129055x20600120\">https://doi.org/10.1142/s0129055x20600120</a>","mla":"Seiringer, Robert. “The Polaron at Strong Coupling.” <i>Reviews in Mathematical Physics</i>, vol. 33, no. 01, 2060012, World Scientific Publishing, 2021, doi:<a href=\"https://doi.org/10.1142/s0129055x20600120\">10.1142/s0129055x20600120</a>.","ista":"Seiringer R. 2021. The polaron at strong coupling. Reviews in Mathematical Physics. 33(01), 2060012.","ieee":"R. Seiringer, “The polaron at strong coupling,” <i>Reviews in Mathematical Physics</i>, vol. 33, no. 01. World Scientific Publishing, 2021."},"doi":"10.1142/s0129055x20600120","arxiv":1,"intvolume":"        33","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0129-055X"],"eissn":["1793-6659"]},"year":"2021","external_id":{"isi":["000613313200013"],"arxiv":["1912.12509"]},"isi":1,"keyword":["Mathematical Physics","Statistical and Nonlinear Physics"],"abstract":[{"text":" We review old and new results on the Fröhlich polaron model. The discussion includes the validity of the (classical) Pekar approximation in the strong coupling limit, quantum corrections to this limit, as well as the divergence of the effective polaron mass.","lang":"eng"}],"oa":1,"department":[{"_id":"RoSe"}],"author":[{"orcid":"0000-0002-6781-0521","full_name":"Seiringer, Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","last_name":"Seiringer"}],"publication":"Reviews in Mathematical Physics","_id":"10852","issue":"01","article_processing_charge":"No","type":"journal_article","oa_version":"Preprint","date_created":"2022-03-18T08:11:34Z","project":[{"name":"Analysis of quantum many-body systems","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","grant_number":"694227","call_identifier":"H2020"}],"status":"public","article_number":"2060012","title":"The polaron at strong coupling","volume":33,"day":"01","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1912.12509"}],"date_updated":"2023-09-05T16:08:02Z","publisher":"World Scientific Publishing","publication_status":"published","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_type":"original","month":"02","date_published":"2021-02-01T00:00:00Z"},{"month":"09","date_published":"2020-09-08T00:00:00Z","article_type":"original","publisher":"Springer Nature","date_updated":"2024-08-07T07:11:51Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publication_status":"published","_id":"8529","article_processing_charge":"No","type":"journal_article","publication":"Nature Communications","file_date_updated":"2020-09-18T13:02:37Z","project":[{"call_identifier":"H2020","grant_number":"732894","name":"Hybrid Optomechanical Technologies","_id":"257EB838-B435-11E9-9278-68D0E5697425"},{"grant_number":"758053","call_identifier":"H2020","name":"A Fiber Optic Transceiver for Superconducting Qubits","_id":"26336814-B435-11E9-9278-68D0E5697425"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","grant_number":"754411"},{"grant_number":"862644","call_identifier":"H2020","name":"Quantum readout techniques and technologies","_id":"237CBA6C-32DE-11EA-91FC-C7463DDC885E"},{"_id":"2671EB66-B435-11E9-9278-68D0E5697425","name":"Coherent on-chip conversion of superconducting qubit signals from microwaves to optical frequencies"}],"date_created":"2020-09-18T10:56:20Z","oa_version":"Published Version","department":[{"_id":"JoFi"}],"acknowledged_ssus":[{"_id":"NanoFab"}],"author":[{"id":"3770C838-F248-11E8-B48F-1D18A9856A87","first_name":"Georg M","last_name":"Arnold","orcid":"0000-0003-1397-7876","full_name":"Arnold, Georg M"},{"full_name":"Wulf, Matthias","orcid":"0000-0001-6613-1378","last_name":"Wulf","id":"45598606-F248-11E8-B48F-1D18A9856A87","first_name":"Matthias"},{"orcid":"0000-0003-0415-1423","full_name":"Barzanjeh, Shabir","last_name":"Barzanjeh","id":"2D25E1F6-F248-11E8-B48F-1D18A9856A87","first_name":"Shabir"},{"full_name":"Redchenko, Elena","last_name":"Redchenko","first_name":"Elena","id":"2C21D6E8-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0001-6249-5860","full_name":"Rueda Sanchez, Alfredo R","last_name":"Rueda Sanchez","id":"3B82B0F8-F248-11E8-B48F-1D18A9856A87","first_name":"Alfredo R"},{"id":"29705398-F248-11E8-B48F-1D18A9856A87","first_name":"William J","last_name":"Hease","orcid":"0000-0001-9868-2166","full_name":"Hease, William J"},{"orcid":"0000-0001-6937-5773","full_name":"Hassani, Farid","last_name":"Hassani","id":"2AED110C-F248-11E8-B48F-1D18A9856A87","first_name":"Farid"},{"full_name":"Fink, Johannes M","orcid":"0000-0001-8112-028X","last_name":"Fink","id":"4B591CBA-F248-11E8-B48F-1D18A9856A87","first_name":"Johannes M"}],"day":"08","article_number":"4460","status":"public","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Converting microwave and telecom photons with a silicon photonic nanomechanical interface","volume":11,"external_id":{"isi":["000577280200001"]},"isi":1,"file":[{"file_id":"8530","access_level":"open_access","date_created":"2020-09-18T13:02:37Z","content_type":"application/pdf","success":1,"file_name":"2020_NatureComm_Arnold.pdf","relation":"main_file","checksum":"88f92544889eb18bb38e25629a422a86","file_size":1002818,"creator":"dernst","date_updated":"2020-09-18T13:02:37Z"}],"oa":1,"ddc":["530"],"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"abstract":[{"lang":"eng","text":"Practical quantum networks require low-loss and noise-resilient optical interconnects as well as non-Gaussian resources for entanglement distillation and distributed quantum computation. The latter could be provided by superconducting circuits but existing solutions to interface the microwave and optical domains lack either scalability or efficiency, and in most cases the conversion noise is not known. In this work we utilize the unique opportunities of silicon photonics, cavity optomechanics and superconducting circuits to demonstrate a fully integrated, coherent transducer interfacing the microwave X and the telecom S bands with a total (internal) bidirectional transduction efficiency of 1.2% (135%) at millikelvin temperatures. The coupling relies solely on the radiation pressure interaction mediated by the femtometer-scale motion of two silicon nanobeams reaching a <jats:italic>V</jats:italic><jats:sub><jats:italic>π</jats:italic></jats:sub> as low as 16 μV for sub-nanowatt pump powers. Without the associated optomechanical gain, we achieve a total (internal) pure conversion efficiency of up to 0.019% (1.6%), relevant for future noise-free operation on this qubit-compatible platform."}],"doi":"10.1038/s41467-020-18269-z","citation":{"ama":"Arnold GM, Wulf M, Barzanjeh S, et al. Converting microwave and telecom photons with a silicon photonic nanomechanical interface. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-18269-z\">10.1038/s41467-020-18269-z</a>","short":"G.M. Arnold, M. Wulf, S. Barzanjeh, E. Redchenko, A.R. Rueda Sanchez, W.J. Hease, F. Hassani, J.M. Fink, Nature Communications 11 (2020).","chicago":"Arnold, Georg M, Matthias Wulf, Shabir Barzanjeh, Elena Redchenko, Alfredo R Rueda Sanchez, William J Hease, Farid Hassani, and Johannes M Fink. “Converting Microwave and Telecom Photons with a Silicon Photonic Nanomechanical Interface.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-18269-z\">https://doi.org/10.1038/s41467-020-18269-z</a>.","apa":"Arnold, G. M., Wulf, M., Barzanjeh, S., Redchenko, E., Rueda Sanchez, A. R., Hease, W. J., … Fink, J. M. (2020). Converting microwave and telecom photons with a silicon photonic nanomechanical interface. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-18269-z\">https://doi.org/10.1038/s41467-020-18269-z</a>","mla":"Arnold, Georg M., et al. “Converting Microwave and Telecom Photons with a Silicon Photonic Nanomechanical Interface.” <i>Nature Communications</i>, vol. 11, 4460, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-18269-z\">10.1038/s41467-020-18269-z</a>.","ieee":"G. M. Arnold <i>et al.</i>, “Converting microwave and telecom photons with a silicon photonic nanomechanical interface,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","ista":"Arnold GM, Wulf M, Barzanjeh S, Redchenko E, Rueda Sanchez AR, Hease WJ, Hassani F, Fink JM. 2020. Converting microwave and telecom photons with a silicon photonic nanomechanical interface. Nature Communications. 11, 4460."},"quality_controlled":"1","ec_funded":1,"acknowledgement":"We thank Yuan Chen for performing supplementary FEM simulations and Andrew Higginbotham, Ralf Riedinger, Sungkun Hong, and Lorenzo Magrini for valuable discussions. This work was supported by IST Austria, the IST nanofabrication facility (NFF), the European Union’s Horizon 2020 research and innovation program under grant agreement no. 732894 (FET Proactive HOT) and the European Research Council under grant agreement no. 758053 (ERC StG QUNNECT). G.A. is the recipient of a DOC fellowship of the Austrian Academy of Sciences at IST Austria. W.H. is the recipient of an ISTplus postdoctoral fellowship with funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement no. 754411. J.M.F. acknowledges support from the Austrian Science Fund (FWF) through BeyondC (F71), a NOMIS foundation research grant, and the EU’s Horizon 2020 research and innovation program under grant agreement no. 862644 (FET Open QUARTET).","related_material":{"record":[{"relation":"research_data","id":"13056","status":"public"}],"link":[{"url":"https://doi.org/10.1038/s41467-020-18912-9","relation":"erratum"},{"relation":"press_release","url":"https://ist.ac.at/en/news/how-to-transport-microwave-quantum-information-via-optical-fiber/","description":"News on IST Homepage"}]},"language":[{"iso":"eng"}],"publication_identifier":{"issn":["2041-1723"]},"year":"2020","intvolume":"        11","has_accepted_license":"1"},{"isi":1,"external_id":{"isi":["000573756600004"]},"abstract":[{"text":"Aqueous iodine based electrochemical energy storage is considered a potential candidate to improve sustainability and performance of current battery and supercapacitor technology. It harnesses the redox activity of iodide, iodine, and polyiodide species in the confined geometry of nanoporous carbon electrodes. However, current descriptions of the electrochemical reaction mechanism to interconvert these species are elusive. Here we show that electrochemical oxidation of iodide in nanoporous carbons forms persistent solid iodine deposits. Confinement slows down dissolution into triiodide and pentaiodide, responsible for otherwise significant self-discharge via shuttling. The main tools for these insights are in situ Raman spectroscopy and in situ small and wide-angle X-ray scattering (in situ SAXS/WAXS). In situ Raman confirms the reversible formation of triiodide and pentaiodide. In situ SAXS/WAXS indicates remarkable amounts of solid iodine deposited in the carbon nanopores. Combined with stochastic modeling, in situ SAXS allows quantifying the solid iodine volume fraction and visualizing the iodine structure on 3D lattice models at the sub-nanometer scale. Based on the derived mechanism, we demonstrate strategies for improved iodine pore filling capacity and prevention of self-discharge, applicable to hybrid supercapacitors and batteries.","lang":"eng"}],"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"ddc":["530"],"oa":1,"file":[{"file_id":"8585","date_created":"2020-09-28T13:16:15Z","access_level":"open_access","success":1,"content_type":"application/pdf","relation":"main_file","file_name":"2020_NatureComm_Prehal.pdf","checksum":"eada7bc8dd16a49390137cff882ef328","file_size":1822469,"creator":"dernst","date_updated":"2020-09-28T13:16:15Z"}],"related_material":{"link":[{"relation":"erratum","url":"https://doi.org/10.1038/s41467-020-19720-x"}]},"quality_controlled":"1","citation":{"ama":"Prehal C, Fitzek H, Kothleitner G, et al. Persistent and reversible solid iodine electrodeposition in nanoporous carbons. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-18610-6\">10.1038/s41467-020-18610-6</a>","chicago":"Prehal, Christian, Harald Fitzek, Gerald Kothleitner, Volker Presser, Bernhard Gollas, Stefan Alexander Freunberger, and Qamar Abbas. “Persistent and Reversible Solid Iodine Electrodeposition in Nanoporous Carbons.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-18610-6\">https://doi.org/10.1038/s41467-020-18610-6</a>.","short":"C. Prehal, H. Fitzek, G. Kothleitner, V. Presser, B. Gollas, S.A. Freunberger, Q. Abbas, Nature Communications 11 (2020).","apa":"Prehal, C., Fitzek, H., Kothleitner, G., Presser, V., Gollas, B., Freunberger, S. A., &#38; Abbas, Q. (2020). Persistent and reversible solid iodine electrodeposition in nanoporous carbons. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-18610-6\">https://doi.org/10.1038/s41467-020-18610-6</a>","mla":"Prehal, Christian, et al. “Persistent and Reversible Solid Iodine Electrodeposition in Nanoporous Carbons.” <i>Nature Communications</i>, vol. 11, 4838, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-18610-6\">10.1038/s41467-020-18610-6</a>.","ieee":"C. Prehal <i>et al.</i>, “Persistent and reversible solid iodine electrodeposition in nanoporous carbons,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","ista":"Prehal C, Fitzek H, Kothleitner G, Presser V, Gollas B, Freunberger SA, Abbas Q. 2020. Persistent and reversible solid iodine electrodeposition in nanoporous carbons. Nature Communications. 11, 4838."},"doi":"10.1038/s41467-020-18610-6","has_accepted_license":"1","intvolume":"        11","year":"2020","language":[{"iso":"eng"}],"publication_identifier":{"issn":["2041-1723"]},"publication_status":"published","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-22T09:37:24Z","publisher":"Springer Nature","article_type":"original","month":"09","date_published":"2020-09-24T00:00:00Z","author":[{"full_name":"Prehal, Christian","last_name":"Prehal","first_name":"Christian"},{"full_name":"Fitzek, Harald","last_name":"Fitzek","first_name":"Harald"},{"full_name":"Kothleitner, Gerald","last_name":"Kothleitner","first_name":"Gerald"},{"full_name":"Presser, Volker","last_name":"Presser","first_name":"Volker"},{"full_name":"Gollas, Bernhard","first_name":"Bernhard","last_name":"Gollas"},{"first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","last_name":"Freunberger","full_name":"Freunberger, Stefan Alexander","orcid":"0000-0003-2902-5319"},{"full_name":"Abbas, Qamar","last_name":"Abbas","first_name":"Qamar"}],"department":[{"_id":"StFr"}],"oa_version":"Published Version","date_created":"2020-09-25T07:23:13Z","publication":"Nature Communications","file_date_updated":"2020-09-28T13:16:15Z","_id":"8568","article_processing_charge":"No","type":"journal_article","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Persistent and reversible solid iodine electrodeposition in nanoporous carbons","volume":11,"status":"public","article_number":"4838","day":"24"},{"external_id":{"isi":["000530448300001"],"arxiv":["1912.02658"]},"isi":1,"keyword":["Physical and Theoretical Chemistry","General Physics and Astronomy"],"abstract":[{"text":"Inspired by the possibility to experimentally manipulate and enhance chemical reactivity in helium nanodroplets, we investigate the effective interaction and the resulting correlations between two diatomic molecules immersed in a bath of bosons. By analogy with the bipolaron, we introduce the biangulon quasiparticle describing two rotating molecules that align with respect to each other due to the effective attractive interaction mediated by the excitations of the bath. We study this system in different parameter regimes and apply several theoretical approaches to describe its properties. Using a Born–Oppenheimer approximation, we investigate the dependence of the effective intermolecular interaction on the rotational state of the two molecules. In the strong-coupling regime, a product-state ansatz shows that the molecules tend to have a strong alignment in the ground state. To investigate the system in the weak-coupling regime, we apply a one-phonon excitation variational ansatz, which allows us to access the energy spectrum. In comparison to the angulon quasiparticle, the biangulon shows shifted angulon instabilities and an additional spectral instability, where resonant angular momentum transfer between the molecules and the bath takes place. These features are proposed as an experimentally observable signature for the formation of the biangulon quasiparticle. Finally, by using products of single angulon and bare impurity wave functions as basis states, we introduce a diagonalization scheme that allows us to describe the transition from two separated angulons to a biangulon as a function of the distance between the two molecules.","lang":"eng"}],"oa":1,"ec_funded":1,"quality_controlled":"1","citation":{"ama":"Li X, Yakaboylu E, Bighin G, Schmidt R, Lemeshko M, Deuchert A. Intermolecular forces and correlations mediated by a phonon bath. <i>The Journal of Chemical Physics</i>. 2020;152(16). doi:<a href=\"https://doi.org/10.1063/1.5144759\">10.1063/1.5144759</a>","apa":"Li, X., Yakaboylu, E., Bighin, G., Schmidt, R., Lemeshko, M., &#38; Deuchert, A. (2020). Intermolecular forces and correlations mediated by a phonon bath. <i>The Journal of Chemical Physics</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/1.5144759\">https://doi.org/10.1063/1.5144759</a>","short":"X. Li, E. Yakaboylu, G. Bighin, R. Schmidt, M. Lemeshko, A. Deuchert, The Journal of Chemical Physics 152 (2020).","chicago":"Li, Xiang, Enderalp Yakaboylu, Giacomo Bighin, Richard Schmidt, Mikhail Lemeshko, and Andreas Deuchert. “Intermolecular Forces and Correlations Mediated by a Phonon Bath.” <i>The Journal of Chemical Physics</i>. AIP Publishing, 2020. <a href=\"https://doi.org/10.1063/1.5144759\">https://doi.org/10.1063/1.5144759</a>.","ieee":"X. Li, E. Yakaboylu, G. Bighin, R. Schmidt, M. Lemeshko, and A. Deuchert, “Intermolecular forces and correlations mediated by a phonon bath,” <i>The Journal of Chemical Physics</i>, vol. 152, no. 16. AIP Publishing, 2020.","ista":"Li X, Yakaboylu E, Bighin G, Schmidt R, Lemeshko M, Deuchert A. 2020. Intermolecular forces and correlations mediated by a phonon bath. The Journal of Chemical Physics. 152(16), 164302.","mla":"Li, Xiang, et al. “Intermolecular Forces and Correlations Mediated by a Phonon Bath.” <i>The Journal of Chemical Physics</i>, vol. 152, no. 16, 164302, AIP Publishing, 2020, doi:<a href=\"https://doi.org/10.1063/1.5144759\">10.1063/1.5144759</a>."},"doi":"10.1063/1.5144759","acknowledgement":"We are grateful to Areg Ghazaryan for valuable discussions. M.L. acknowledges support from the Austrian Science Fund (FWF) under Project No. P29902-N27 and from the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). G.B. acknowledges support from the Austrian Science Fund (FWF) under Project No. M2461-N27. A.D. acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the European Research Council (ERC) Grant Agreement No. 694227 and under the Marie Sklodowska-Curie Grant Agreement No. 836146. R.S. was supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC-2111 – 390814868.","related_material":{"record":[{"id":"8958","status":"public","relation":"dissertation_contains"}]},"publication_identifier":{"issn":["0021-9606"],"eissn":["1089-7690"]},"language":[{"iso":"eng"}],"year":"2020","intvolume":"       152","arxiv":1,"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1912.02658"}],"article_type":"original","month":"04","date_published":"2020-04-27T00:00:00Z","date_updated":"2024-08-07T07:16:53Z","publisher":"AIP Publishing","publication_status":"published","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publication":"The Journal of Chemical Physics","_id":"8587","issue":"16","type":"journal_article","article_processing_charge":"No","date_created":"2020-09-30T10:33:17Z","oa_version":"Preprint","project":[{"_id":"26031614-B435-11E9-9278-68D0E5697425","name":"Quantum rotations in the presence of a many-body environment","grant_number":"P29902","call_identifier":"FWF"},{"_id":"2688CF98-B435-11E9-9278-68D0E5697425","name":"Angulon: physics and applications of a new quasiparticle","grant_number":"801770","call_identifier":"H2020"},{"name":"A path-integral approach to composite impurities","_id":"26986C82-B435-11E9-9278-68D0E5697425","grant_number":"M02641","call_identifier":"FWF"},{"call_identifier":"H2020","grant_number":"694227","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","name":"Analysis of quantum many-body systems"}],"department":[{"_id":"MiLe"},{"_id":"RoSe"}],"author":[{"last_name":"Li","id":"4B7E523C-F248-11E8-B48F-1D18A9856A87","first_name":"Xiang","full_name":"Li, Xiang"},{"orcid":"0000-0001-5973-0874","full_name":"Yakaboylu, Enderalp","id":"38CB71F6-F248-11E8-B48F-1D18A9856A87","first_name":"Enderalp","last_name":"Yakaboylu"},{"first_name":"Giacomo","id":"4CA96FD4-F248-11E8-B48F-1D18A9856A87","last_name":"Bighin","orcid":"0000-0001-8823-9777","full_name":"Bighin, Giacomo"},{"first_name":"Richard","last_name":"Schmidt","full_name":"Schmidt, Richard"},{"first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko","orcid":"0000-0002-6990-7802","full_name":"Lemeshko, Mikhail"},{"last_name":"Deuchert","first_name":"Andreas","id":"4DA65CD0-F248-11E8-B48F-1D18A9856A87","full_name":"Deuchert, Andreas","orcid":"0000-0003-3146-6746"}],"day":"27","status":"public","article_number":"164302","title":"Intermolecular forces and correlations mediated by a phonon bath","volume":152},{"acknowledgement":"The authors thank Drs. J. Eisen, QR. Lu, S. Duan, Z‐H. Li, W. Mo, and Q. Wu for their critical comments on the manuscript. They also thank Dr. H. Zong for providing the CKO_NG2‐CreER model. This work is supported by the National Key Research and Development Program of China, Stem Cell and Translational Research (2016YFA0101201 to C.L., 2016YFA0100303 to Y.J.W.), the National Natural Science Foundation of China (81673035 and 81972915 to C.L., 81472722 to Y.J.W.), the Science Foundation for Distinguished Young Scientists of Zhejiang Province (LR17H160001 to C.L.), Fundamental Research Funds for the Central Universities (2016QNA7023 and 2017QNA7028 to C.L.) and the Thousand Talent Program for Young Outstanding Scientists, China (to C.L.), IST Austria institutional funds (to S.H.), European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (725780 LinPro to S.H.). C.L. is a scholar of K. C. Wong Education Foundation.","doi":"10.1002/advs.202001724","citation":{"mla":"Tian, Anhao, et al. “Oncogenic State and Cell Identity Combinatorially Dictate the Susceptibility of Cells within Glioma Development Hierarchy to IGF1R Targeting.” <i>Advanced Science</i>, vol. 7, no. 21, 2001724, Wiley, 2020, doi:<a href=\"https://doi.org/10.1002/advs.202001724\">10.1002/advs.202001724</a>.","ieee":"A. Tian <i>et al.</i>, “Oncogenic state and cell identity combinatorially dictate the susceptibility of cells within glioma development hierarchy to IGF1R targeting,” <i>Advanced Science</i>, vol. 7, no. 21. Wiley, 2020.","ista":"Tian A, Kang B, Li B, Qiu B, Jiang W, Shao F, Gao Q, Liu R, Cai C, Jing R, Wang W, Chen P, Liang Q, Bao L, Man J, Wang Y, Shi Y, Li J, Yang M, Wang L, Zhang J, Hippenmeyer S, Zhu J, Bian X, Wang Y, Liu C. 2020. Oncogenic state and cell identity combinatorially dictate the susceptibility of cells within glioma development hierarchy to IGF1R targeting. Advanced Science. 7(21), 2001724.","chicago":"Tian, Anhao, Bo Kang, Baizhou Li, Biying Qiu, Wenhong Jiang, Fangjie Shao, Qingqing Gao, et al. “Oncogenic State and Cell Identity Combinatorially Dictate the Susceptibility of Cells within Glioma Development Hierarchy to IGF1R Targeting.” <i>Advanced Science</i>. Wiley, 2020. <a href=\"https://doi.org/10.1002/advs.202001724\">https://doi.org/10.1002/advs.202001724</a>.","short":"A. Tian, B. Kang, B. Li, B. Qiu, W. Jiang, F. Shao, Q. Gao, R. Liu, C. Cai, R. Jing, W. Wang, P. Chen, Q. Liang, L. Bao, J. Man, Y. Wang, Y. Shi, J. Li, M. Yang, L. Wang, J. Zhang, S. Hippenmeyer, J. Zhu, X. Bian, Y. Wang, C. Liu, Advanced Science 7 (2020).","apa":"Tian, A., Kang, B., Li, B., Qiu, B., Jiang, W., Shao, F., … Liu, C. (2020). Oncogenic state and cell identity combinatorially dictate the susceptibility of cells within glioma development hierarchy to IGF1R targeting. <i>Advanced Science</i>. Wiley. <a href=\"https://doi.org/10.1002/advs.202001724\">https://doi.org/10.1002/advs.202001724</a>","ama":"Tian A, Kang B, Li B, et al. Oncogenic state and cell identity combinatorially dictate the susceptibility of cells within glioma development hierarchy to IGF1R targeting. <i>Advanced Science</i>. 2020;7(21). doi:<a href=\"https://doi.org/10.1002/advs.202001724\">10.1002/advs.202001724</a>"},"quality_controlled":"1","ec_funded":1,"intvolume":"         7","has_accepted_license":"1","publication_identifier":{"issn":["2198-3844"]},"language":[{"iso":"eng"}],"year":"2020","external_id":{"isi":["000573860700001"]},"isi":1,"file":[{"date_updated":"2020-12-10T14:07:24Z","checksum":"92818c23ecc70e35acfa671f3cfb9909","file_size":7835833,"creator":"dernst","content_type":"application/pdf","success":1,"file_name":"2020_AdvScience_Tian.pdf","relation":"main_file","file_id":"8938","date_created":"2020-12-10T14:07:24Z","access_level":"open_access"}],"oa":1,"ddc":["570"],"keyword":["General Engineering","General Physics and Astronomy","General Materials Science","Medicine (miscellaneous)","General Chemical Engineering","Biochemistry","Genetics and Molecular Biology (miscellaneous)"],"abstract":[{"text":"Glioblastoma is the most malignant cancer in the brain and currently incurable. It is urgent to identify effective targets for this lethal disease. Inhibition of such targets should suppress the growth of cancer cells and, ideally also precancerous cells for early prevention, but minimally affect their normal counterparts. Using genetic mouse models with neural stem cells (NSCs) or oligodendrocyte precursor cells (OPCs) as the cells‐of‐origin/mutation, it is shown that the susceptibility of cells within the development hierarchy of glioma to the knockout of insulin‐like growth factor I receptor (IGF1R) is determined not only by their oncogenic states, but also by their cell identities/states. Knockout of IGF1R selectively disrupts the growth of mutant and transformed, but not normal OPCs, or NSCs. The desirable outcome of IGF1R knockout on cell growth requires the mutant cells to commit to the OPC identity regardless of its development hierarchical status. At the molecular level, oncogenic mutations reprogram the cellular network of OPCs and force them to depend more on IGF1R for their growth. A new‐generation brain‐penetrable, orally available IGF1R inhibitor harnessing tumor OPCs in the brain is also developed. The findings reveal the cellular window of IGF1R targeting and establish IGF1R as an effective target for the prevention and treatment of glioblastoma.","lang":"eng"}],"department":[{"_id":"SiHi"}],"author":[{"first_name":"Anhao","last_name":"Tian","full_name":"Tian, Anhao"},{"full_name":"Kang, Bo","last_name":"Kang","first_name":"Bo"},{"last_name":"Li","first_name":"Baizhou","full_name":"Li, Baizhou"},{"first_name":"Biying","last_name":"Qiu","full_name":"Qiu, Biying"},{"last_name":"Jiang","first_name":"Wenhong","full_name":"Jiang, Wenhong"},{"first_name":"Fangjie","last_name":"Shao","full_name":"Shao, Fangjie"},{"last_name":"Gao","first_name":"Qingqing","full_name":"Gao, Qingqing"},{"full_name":"Liu, Rui","last_name":"Liu","first_name":"Rui"},{"last_name":"Cai","first_name":"Chengwei","full_name":"Cai, Chengwei"},{"first_name":"Rui","last_name":"Jing","full_name":"Jing, Rui"},{"first_name":"Wei","last_name":"Wang","full_name":"Wang, Wei"},{"last_name":"Chen","first_name":"Pengxiang","full_name":"Chen, Pengxiang"},{"last_name":"Liang","first_name":"Qinghui","full_name":"Liang, Qinghui"},{"full_name":"Bao, Lili","last_name":"Bao","first_name":"Lili"},{"last_name":"Man","first_name":"Jianghong","full_name":"Man, Jianghong"},{"full_name":"Wang, Yan","last_name":"Wang","first_name":"Yan"},{"full_name":"Shi, Yu","first_name":"Yu","last_name":"Shi"},{"last_name":"Li","first_name":"Jin","full_name":"Li, Jin"},{"full_name":"Yang, Minmin","last_name":"Yang","first_name":"Minmin"},{"full_name":"Wang, Lisha","first_name":"Lisha","last_name":"Wang"},{"full_name":"Zhang, Jianmin","first_name":"Jianmin","last_name":"Zhang"},{"full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","last_name":"Hippenmeyer"},{"first_name":"Junming","last_name":"Zhu","full_name":"Zhu, Junming"},{"first_name":"Xiuwu","last_name":"Bian","full_name":"Bian, Xiuwu"},{"full_name":"Wang, Ying‐Jie","last_name":"Wang","first_name":"Ying‐Jie"},{"full_name":"Liu, Chong","first_name":"Chong","last_name":"Liu"}],"article_processing_charge":"No","_id":"8592","issue":"21","type":"journal_article","file_date_updated":"2020-12-10T14:07:24Z","publication":"Advanced Science","project":[{"_id":"260018B0-B435-11E9-9278-68D0E5697425","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","call_identifier":"H2020","grant_number":"725780"}],"oa_version":"Published Version","date_created":"2020-10-01T09:44:13Z","article_number":"2001724","status":"public","volume":7,"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Oncogenic state and cell identity combinatorially dictate the susceptibility of cells within glioma development hierarchy to IGF1R targeting","day":"04","publisher":"Wiley","date_updated":"2023-08-22T09:53:01Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publication_status":"published","month":"11","date_published":"2020-11-04T00:00:00Z","article_type":"original"},{"day":"05","volume":125,"title":"Capturing turbulent dynamics and statistics in experiments with unstable periodic orbits","article_number":"064501","status":"public","project":[{"call_identifier":"FP7","grant_number":"291734","name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"oa_version":"Preprint","date_created":"2020-10-08T17:27:32Z","issue":"6","_id":"8634","article_processing_charge":"No","type":"journal_article","publication":"Physical Review Letters","author":[{"last_name":"Suri","id":"47A5E706-F248-11E8-B48F-1D18A9856A87","first_name":"Balachandra","full_name":"Suri, Balachandra"},{"last_name":"Kageorge","first_name":"Logan","full_name":"Kageorge, Logan"},{"full_name":"Grigoriev, Roman O.","last_name":"Grigoriev","first_name":"Roman O."},{"first_name":"Michael F.","last_name":"Schatz","full_name":"Schatz, Michael F."}],"department":[{"_id":"BjHo"}],"month":"08","date_published":"2020-08-05T00:00:00Z","article_type":"original","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publication_status":"published","publisher":"American Physical Society","date_updated":"2023-09-05T12:08:29Z","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2008.02367"}],"year":"2020","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"intvolume":"       125","arxiv":1,"citation":{"mla":"Suri, Balachandra, et al. “Capturing Turbulent Dynamics and Statistics in Experiments with Unstable Periodic Orbits.” <i>Physical Review Letters</i>, vol. 125, no. 6, 064501, American Physical Society, 2020, doi:<a href=\"https://doi.org/10.1103/physrevlett.125.064501\">10.1103/physrevlett.125.064501</a>.","ieee":"B. Suri, L. Kageorge, R. O. Grigoriev, and M. F. Schatz, “Capturing turbulent dynamics and statistics in experiments with unstable periodic orbits,” <i>Physical Review Letters</i>, vol. 125, no. 6. American Physical Society, 2020.","ista":"Suri B, Kageorge L, Grigoriev RO, Schatz MF. 2020. Capturing turbulent dynamics and statistics in experiments with unstable periodic orbits. Physical Review Letters. 125(6), 064501.","chicago":"Suri, Balachandra, Logan Kageorge, Roman O. Grigoriev, and Michael F. Schatz. “Capturing Turbulent Dynamics and Statistics in Experiments with Unstable Periodic Orbits.” <i>Physical Review Letters</i>. American Physical Society, 2020. <a href=\"https://doi.org/10.1103/physrevlett.125.064501\">https://doi.org/10.1103/physrevlett.125.064501</a>.","short":"B. Suri, L. Kageorge, R.O. Grigoriev, M.F. Schatz, Physical Review Letters 125 (2020).","apa":"Suri, B., Kageorge, L., Grigoriev, R. O., &#38; Schatz, M. F. (2020). Capturing turbulent dynamics and statistics in experiments with unstable periodic orbits. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevlett.125.064501\">https://doi.org/10.1103/physrevlett.125.064501</a>","ama":"Suri B, Kageorge L, Grigoriev RO, Schatz MF. Capturing turbulent dynamics and statistics in experiments with unstable periodic orbits. <i>Physical Review Letters</i>. 2020;125(6). doi:<a href=\"https://doi.org/10.1103/physrevlett.125.064501\">10.1103/physrevlett.125.064501</a>"},"doi":"10.1103/physrevlett.125.064501","quality_controlled":"1","ec_funded":1,"acknowledgement":"M. F. S. and R. O. G. acknowledge funding from the National Science Foundation (CMMI-1234436, DMS1125302, CMMI-1725587) and Defense Advanced Research Projects Agency (HR0011-16-2-0033). B. S.has received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme FP7/2007–2013/ under REA Grant Agreement No. 291734.","oa":1,"abstract":[{"text":"In laboratory studies and numerical simulations, we observe clear signatures of unstable time-periodic solutions in a moderately turbulent quasi-two-dimensional flow. We validate the dynamical relevance of such solutions by demonstrating that turbulent flows in both experiment and numerics transiently display time-periodic dynamics when they shadow unstable periodic orbits (UPOs). We show that UPOs we computed are also statistically significant, with turbulent flows spending a sizable fraction of the total time near these solutions. As a result, the average rates of energy input and dissipation for the turbulent flow and frequently visited UPOs differ only by a few percent.","lang":"eng"}],"keyword":["General Physics and Astronomy"],"isi":1,"external_id":{"arxiv":["2008.02367"],"isi":["000555785600005"]}},{"date_updated":"2023-08-22T12:36:07Z","publisher":"Springer Nature","publication_status":"published","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_type":"original","date_published":"2020-11-04T00:00:00Z","month":"11","scopus_import":"1","status":"public","article_number":"5569","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"volume":11,"title":"Cysteine oxidation and disulfide formation in the ribosomal exit tunnel","day":"04","department":[{"_id":"EM-Fac"}],"author":[{"first_name":"Linda","last_name":"Schulte","full_name":"Schulte, Linda"},{"full_name":"Mao, Jiafei","last_name":"Mao","first_name":"Jiafei"},{"full_name":"Reitz, Julian","first_name":"Julian","last_name":"Reitz"},{"full_name":"Sreeramulu, Sridhar","first_name":"Sridhar","last_name":"Sreeramulu"},{"full_name":"Kudlinzki, Denis","last_name":"Kudlinzki","first_name":"Denis"},{"full_name":"Hodirnau, Victor-Valentin","last_name":"Hodirnau","first_name":"Victor-Valentin","id":"3661B498-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Meier-Credo, Jakob","first_name":"Jakob","last_name":"Meier-Credo"},{"full_name":"Saxena, Krishna","last_name":"Saxena","first_name":"Krishna"},{"full_name":"Buhr, Florian","last_name":"Buhr","first_name":"Florian"},{"first_name":"Julian D.","last_name":"Langer","full_name":"Langer, Julian D."},{"last_name":"Blackledge","first_name":"Martin","full_name":"Blackledge, Martin"},{"last_name":"Frangakis","first_name":"Achilleas S.","full_name":"Frangakis, Achilleas S."},{"full_name":"Glaubitz, Clemens","last_name":"Glaubitz","first_name":"Clemens"},{"full_name":"Schwalbe, Harald","first_name":"Harald","last_name":"Schwalbe"}],"file_date_updated":"2020-11-09T07:56:24Z","publication":"Nature Communications","type":"journal_article","_id":"8744","article_processing_charge":"No","date_created":"2020-11-09T07:49:36Z","oa_version":"Published Version","file":[{"date_created":"2020-11-09T07:56:24Z","access_level":"open_access","file_id":"8745","relation":"main_file","file_name":"2020_NatureComm_Schulte.pdf","success":1,"content_type":"application/pdf","creator":"dernst","file_size":1670898,"checksum":"b2688f0347e69e6629bba582077278c5","date_updated":"2020-11-09T07:56:24Z"}],"abstract":[{"text":"Understanding the conformational sampling of translation-arrested ribosome nascent chain complexes is key to understand co-translational folding. Up to now, coupling of cysteine oxidation, disulfide bond formation and structure formation in nascent chains has remained elusive. Here, we investigate the eye-lens protein γB-crystallin in the ribosomal exit tunnel. Using mass spectrometry, theoretical simulations, dynamic nuclear polarization-enhanced solid-state nuclear magnetic resonance and cryo-electron microscopy, we show that thiol groups of cysteine residues undergo S-glutathionylation and S-nitrosylation and form non-native disulfide bonds. Thus, covalent modification chemistry occurs already prior to nascent chain release as the ribosome exit tunnel provides sufficient space even for disulfide bond formation which can guide protein folding.","lang":"eng"}],"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"ddc":["570"],"oa":1,"external_id":{"isi":["000592028600001"]},"isi":1,"intvolume":"        11","has_accepted_license":"1","language":[{"iso":"eng"}],"publication_identifier":{"issn":["2041-1723"]},"year":"2020","acknowledgement":"We acknowledge help from Anja Seybert, Margot Frangakis, Diana Grewe, Mikhail Eltsov, Utz Ermel, and Shintaro Aibara. The work was supported by Deutsche Forschungsgemeinschaft in the CLiC graduate school. Work at the Center for Biomolecular Magnetic Resonance (BMRZ) is supported by the German state of Hesse. The work at BMRZ has been supported by the state of Hesse. L.S. has been supported by the DFG graduate college: CLiC.","quality_controlled":"1","citation":{"ieee":"L. Schulte <i>et al.</i>, “Cysteine oxidation and disulfide formation in the ribosomal exit tunnel,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","ista":"Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D, Hodirnau V-V, Meier-Credo J, Saxena K, Buhr F, Langer JD, Blackledge M, Frangakis AS, Glaubitz C, Schwalbe H. 2020. Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. Nature Communications. 11, 5569.","mla":"Schulte, Linda, et al. “Cysteine Oxidation and Disulfide Formation in the Ribosomal Exit Tunnel.” <i>Nature Communications</i>, vol. 11, 5569, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-19372-x\">10.1038/s41467-020-19372-x</a>.","apa":"Schulte, L., Mao, J., Reitz, J., Sreeramulu, S., Kudlinzki, D., Hodirnau, V.-V., … Schwalbe, H. (2020). Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-19372-x\">https://doi.org/10.1038/s41467-020-19372-x</a>","short":"L. Schulte, J. Mao, J. Reitz, S. Sreeramulu, D. Kudlinzki, V.-V. Hodirnau, J. Meier-Credo, K. Saxena, F. Buhr, J.D. Langer, M. Blackledge, A.S. Frangakis, C. Glaubitz, H. Schwalbe, Nature Communications 11 (2020).","chicago":"Schulte, Linda, Jiafei Mao, Julian Reitz, Sridhar Sreeramulu, Denis Kudlinzki, Victor-Valentin Hodirnau, Jakob Meier-Credo, et al. “Cysteine Oxidation and Disulfide Formation in the Ribosomal Exit Tunnel.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-19372-x\">https://doi.org/10.1038/s41467-020-19372-x</a>.","ama":"Schulte L, Mao J, Reitz J, et al. Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-19372-x\">10.1038/s41467-020-19372-x</a>"},"doi":"10.1038/s41467-020-19372-x"},{"scopus_import":"1","article_type":"original","month":"12","date_published":"2020-12-22T00:00:00Z","publication_status":"published","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-24T11:01:50Z","publisher":"Springer Nature","oa_version":"Published Version","date_created":"2020-12-23T08:25:45Z","project":[{"name":"Structure and isoform diversity of the Arp2/3 complex","_id":"9B954C5C-BA93-11EA-9121-9846C619BF3A","grant_number":"P33367"},{"_id":"2674F658-B435-11E9-9278-68D0E5697425","name":"Protein structure and function in filopodia across scales","call_identifier":"FWF","grant_number":"M02495"}],"file_date_updated":"2020-12-28T08:16:10Z","publication":"Nature Communications","type":"journal_article","_id":"8971","article_processing_charge":"No","author":[{"first_name":"Florian","id":"404F5528-F248-11E8-B48F-1D18A9856A87","last_name":"Fäßler","full_name":"Fäßler, Florian","orcid":"0000-0001-7149-769X"},{"last_name":"Dimchev","id":"38C393BE-F248-11E8-B48F-1D18A9856A87","first_name":"Georgi A","orcid":"0000-0001-8370-6161","full_name":"Dimchev, Georgi A"},{"full_name":"Hodirnau, Victor-Valentin","last_name":"Hodirnau","first_name":"Victor-Valentin","id":"3661B498-F248-11E8-B48F-1D18A9856A87"},{"first_name":"William","last_name":"Wan","full_name":"Wan, William"},{"last_name":"Schur","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian KM","full_name":"Schur, Florian KM","orcid":"0000-0003-4790-8078"}],"acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"Bio"},{"_id":"EM-Fac"}],"department":[{"_id":"FlSc"},{"_id":"EM-Fac"}],"day":"22","title":"Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"volume":11,"status":"public","article_number":"6437","isi":1,"external_id":{"isi":["000603078000003"]},"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"abstract":[{"text":"The actin-related protein (Arp)2/3 complex nucleates branched actin filament networks pivotal for cell migration, endocytosis and pathogen infection. Its activation is tightly regulated and involves complex structural rearrangements and actin filament binding, which are yet to be understood. Here, we report a 9.0 Å resolution structure of the actin filament Arp2/3 complex branch junction in cells using cryo-electron tomography and subtomogram averaging. This allows us to generate an accurate model of the active Arp2/3 complex in the branch junction and its interaction with actin filaments. Notably, our model reveals a previously undescribed set of interactions of the Arp2/3 complex with the mother filament, significantly different to the previous branch junction model. Our structure also indicates a central role for the ArpC3 subunit in stabilizing the active conformation.","lang":"eng"}],"oa":1,"ddc":["570"],"file":[{"file_id":"8975","access_level":"open_access","date_created":"2020-12-28T08:16:10Z","content_type":"application/pdf","success":1,"relation":"main_file","file_name":"2020_NatureComm_Faessler.pdf","checksum":"55d43ea0061cc4027ba45e966e1db8cc","file_size":3958727,"creator":"dernst","date_updated":"2020-12-28T08:16:10Z"}],"quality_controlled":"1","citation":{"mla":"Fäßler, Florian, et al. “Cryo-Electron Tomography Structure of Arp2/3 Complex in Cells Reveals New Insights into the Branch Junction.” <i>Nature Communications</i>, vol. 11, 6437, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-20286-x\">10.1038/s41467-020-20286-x</a>.","ista":"Fäßler F, Dimchev GA, Hodirnau V-V, Wan W, Schur FK. 2020. Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction. Nature Communications. 11, 6437.","ieee":"F. Fäßler, G. A. Dimchev, V.-V. Hodirnau, W. Wan, and F. K. Schur, “Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","short":"F. Fäßler, G.A. Dimchev, V.-V. Hodirnau, W. Wan, F.K. Schur, Nature Communications 11 (2020).","chicago":"Fäßler, Florian, Georgi A Dimchev, Victor-Valentin Hodirnau, William Wan, and Florian KM Schur. “Cryo-Electron Tomography Structure of Arp2/3 Complex in Cells Reveals New Insights into the Branch Junction.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-20286-x\">https://doi.org/10.1038/s41467-020-20286-x</a>.","apa":"Fäßler, F., Dimchev, G. A., Hodirnau, V.-V., Wan, W., &#38; Schur, F. K. (2020). Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-20286-x\">https://doi.org/10.1038/s41467-020-20286-x</a>","ama":"Fäßler F, Dimchev GA, Hodirnau V-V, Wan W, Schur FK. Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-20286-x\">10.1038/s41467-020-20286-x</a>"},"doi":"10.1038/s41467-020-20286-x","related_material":{"link":[{"url":"https://ist.ac.at/en/news/cutting-edge-technology-reveals-structures-within-cells/","description":"News on IST Homepage","relation":"press_release"}]},"acknowledgement":"This research was supported by the Scientific Service Units (SSUs) of IST Austria through resources provided by Scientific Computing (SciComp), the Life Science Facility (LSF), the BioImaging Facility (BIF), and the Electron Microscopy Facility (EMF). We also thank Dimitry Tegunov (MPI for Biophysical Chemistry) for helpful discussions\r\nabout the M software, and Michael Sixt (IST Austria) and Klemens Rottner (Technical University Braunschweig, HZI Braunschweig) for critical reading of the manuscript. We also thank Gregory Voth (University of Chicago) for providing us the MD-derived branch junction model for comparison. The authors acknowledge support from IST Austria and from the Austrian Science Fund (FWF): M02495 to G.D. and Austrian Science Fund (FWF): P33367 to F.K.M.S. ","year":"2020","language":[{"iso":"eng"}],"publication_identifier":{"issn":["2041-1723"]},"has_accepted_license":"1","intvolume":"        11"},{"scopus_import":"1","month":"05","date_published":"2020-05-07T00:00:00Z","article_type":"original","user_id":"D865714E-FA4E-11E9-B85B-F5C5E5697425","publication_status":"published","publisher":"Royal Society of Chemistry ","date_updated":"2023-02-23T13:47:45Z","date_created":"2021-02-01T13:45:11Z","oa_version":"None","type":"journal_article","_id":"9054","issue":"17","article_processing_charge":"No","publication":"Soft Matter","author":[{"last_name":"Youssef","first_name":"Mena","full_name":"Youssef, Mena"},{"last_name":"Morin","first_name":"Alexandre","full_name":"Morin, Alexandre"},{"last_name":"Aubret","first_name":"Antoine","full_name":"Aubret, Antoine"},{"last_name":"Sacanna","first_name":"Stefano","full_name":"Sacanna, Stefano"},{"full_name":"Palacci, Jérémie A","orcid":"0000-0002-7253-9465","first_name":"Jérémie A","id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d","last_name":"Palacci"}],"day":"07","title":"Rapid characterization of neutral polymer brush with a conventional zetameter and a variable pinch of salt","volume":16,"status":"public","page":"4274-4282","external_id":{"pmid":["32307507"]},"keyword":["General Chemistry","Condensed Matter Physics"],"abstract":[{"lang":"eng","text":"The fundamental and practical importance of particle stabilization has motivated various characterization methods for studying polymer brushes on particle surfaces. In this work, we show how one can perform sensitive measurements of neutral polymer coating on colloidal particles using a commercial zetameter and salt solutions. By systematically varying the Debye length, we study the mobility of the polymer-coated particles in an applied electric field and show that the electrophoretic mobility of polymer-coated particles normalized by the mobility of non-coated particles is entirely controlled by the polymer brush and independent of the native surface charge, here controlled with pH, or the surface–ion interaction. Our result is rationalized with a simple hydrodynamic model, allowing for the estimation of characteristics of the polymer coating: the brush length L, and the Brinkman length ξ, determined by its resistance to flows. We demonstrate that the Debye layer provides a convenient and faithful probe to the characterization of polymer coatings on particles. Because the method simply relies on a conventional zetameter, it is widely accessible and offers a practical tool to rapidly probe neutral polymer brushes, an asset in the development and utilization of polymer-coated colloidal particles."}],"citation":{"mla":"Youssef, Mena, et al. “Rapid Characterization of Neutral Polymer Brush with a Conventional Zetameter and a Variable Pinch of Salt.” <i>Soft Matter</i>, vol. 16, no. 17, Royal Society of Chemistry , 2020, pp. 4274–82, doi:<a href=\"https://doi.org/10.1039/c9sm01850f\">10.1039/c9sm01850f</a>.","ista":"Youssef M, Morin A, Aubret A, Sacanna S, Palacci JA. 2020. Rapid characterization of neutral polymer brush with a conventional zetameter and a variable pinch of salt. Soft Matter. 16(17), 4274–4282.","ieee":"M. Youssef, A. Morin, A. Aubret, S. Sacanna, and J. A. Palacci, “Rapid characterization of neutral polymer brush with a conventional zetameter and a variable pinch of salt,” <i>Soft Matter</i>, vol. 16, no. 17. Royal Society of Chemistry , pp. 4274–4282, 2020.","short":"M. Youssef, A. Morin, A. Aubret, S. Sacanna, J.A. Palacci, Soft Matter 16 (2020) 4274–4282.","chicago":"Youssef, Mena, Alexandre Morin, Antoine Aubret, Stefano Sacanna, and Jérémie A Palacci. “Rapid Characterization of Neutral Polymer Brush with a Conventional Zetameter and a Variable Pinch of Salt.” <i>Soft Matter</i>. Royal Society of Chemistry , 2020. <a href=\"https://doi.org/10.1039/c9sm01850f\">https://doi.org/10.1039/c9sm01850f</a>.","apa":"Youssef, M., Morin, A., Aubret, A., Sacanna, S., &#38; Palacci, J. A. (2020). Rapid characterization of neutral polymer brush with a conventional zetameter and a variable pinch of salt. <i>Soft Matter</i>. Royal Society of Chemistry . <a href=\"https://doi.org/10.1039/c9sm01850f\">https://doi.org/10.1039/c9sm01850f</a>","ama":"Youssef M, Morin A, Aubret A, Sacanna S, Palacci JA. Rapid characterization of neutral polymer brush with a conventional zetameter and a variable pinch of salt. <i>Soft Matter</i>. 2020;16(17):4274-4282. doi:<a href=\"https://doi.org/10.1039/c9sm01850f\">10.1039/c9sm01850f</a>"},"doi":"10.1039/c9sm01850f","quality_controlled":"1","extern":"1","year":"2020","language":[{"iso":"eng"}],"publication_identifier":{"issn":["1744-683X"],"eissn":["1744-6848"]},"pmid":1,"intvolume":"        16"},{"file":[{"relation":"main_file","file_name":"2020_NewJournPhys_Speck.pdf","success":1,"content_type":"application/pdf","date_created":"2021-02-18T14:53:33Z","access_level":"open_access","file_id":"9169","date_updated":"2021-02-18T14:53:33Z","creator":"cziletti","checksum":"02759f3ab228c1a061e747155a20f851","file_size":953338}],"ddc":["530"],"oa":1,"keyword":["General Physics and Astronomy"],"intvolume":"        22","has_accepted_license":"1","language":[{"iso":"eng"}],"publication_identifier":{"issn":["1367-2630"]},"year":"2020","extern":"1","doi":"10.1088/1367-2630/ab90d9","citation":{"ama":"Speck T, Tailleur J, Palacci JA. Focus on active colloids and nanoparticles. <i>New Journal of Physics</i>. 2020;22(6). doi:<a href=\"https://doi.org/10.1088/1367-2630/ab90d9\">10.1088/1367-2630/ab90d9</a>","apa":"Speck, T., Tailleur, J., &#38; Palacci, J. A. (2020). Focus on active colloids and nanoparticles. <i>New Journal of Physics</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1367-2630/ab90d9\">https://doi.org/10.1088/1367-2630/ab90d9</a>","chicago":"Speck, Thomas, Julien Tailleur, and Jérémie A Palacci. “Focus on Active Colloids and Nanoparticles.” <i>New Journal of Physics</i>. IOP Publishing, 2020. <a href=\"https://doi.org/10.1088/1367-2630/ab90d9\">https://doi.org/10.1088/1367-2630/ab90d9</a>.","short":"T. Speck, J. Tailleur, J.A. Palacci, New Journal of Physics 22 (2020).","ista":"Speck T, Tailleur J, Palacci JA. 2020. Focus on active colloids and nanoparticles. New Journal of Physics. 22(6), 060201.","ieee":"T. Speck, J. Tailleur, and J. A. Palacci, “Focus on active colloids and nanoparticles,” <i>New Journal of Physics</i>, vol. 22, no. 6. IOP Publishing, 2020.","mla":"Speck, Thomas, et al. “Focus on Active Colloids and Nanoparticles.” <i>New Journal of Physics</i>, vol. 22, no. 6, 060201, IOP Publishing, 2020, doi:<a href=\"https://doi.org/10.1088/1367-2630/ab90d9\">10.1088/1367-2630/ab90d9</a>."},"quality_controlled":"1","publisher":"IOP Publishing","date_updated":"2021-02-18T14:57:39Z","user_id":"D865714E-FA4E-11E9-B85B-F5C5E5697425","publication_status":"published","month":"06","date_published":"2020-06-01T00:00:00Z","article_type":"letter_note","scopus_import":"1","article_number":"060201","status":"public","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Focus on active colloids and nanoparticles","volume":22,"day":"01","author":[{"last_name":"Speck","first_name":"Thomas","full_name":"Speck, Thomas"},{"full_name":"Tailleur, Julien","first_name":"Julien","last_name":"Tailleur"},{"id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d","first_name":"Jérémie A","last_name":"Palacci","orcid":"0000-0002-7253-9465","full_name":"Palacci, Jérémie A"}],"_id":"9164","issue":"6","article_processing_charge":"No","type":"journal_article","file_date_updated":"2021-02-18T14:53:33Z","publication":"New Journal of Physics","date_created":"2021-02-18T14:17:32Z","oa_version":"Published Version"},{"author":[{"last_name":"Grommet","first_name":"Angela B.","full_name":"Grommet, Angela B."},{"full_name":"Feller, Moran","last_name":"Feller","first_name":"Moran"},{"full_name":"Klajn, Rafal","first_name":"Rafal","id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","last_name":"Klajn"}],"oa_version":"None","date_created":"2023-08-01T09:37:39Z","_id":"13367","article_processing_charge":"No","type":"journal_article","publication":"Nature Nanotechnology","title":"Chemical reactivity under nanoconfinement","volume":15,"status":"public","day":"17","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Springer Nature","date_updated":"2023-08-07T10:29:06Z","month":"04","date_published":"2020-04-17T00:00:00Z","article_type":"original","doi":"10.1038/s41565-020-0652-2","citation":{"ieee":"A. B. Grommet, M. Feller, and R. Klajn, “Chemical reactivity under nanoconfinement,” <i>Nature Nanotechnology</i>, vol. 15. Springer Nature, pp. 256–271, 2020.","ista":"Grommet AB, Feller M, Klajn R. 2020. Chemical reactivity under nanoconfinement. Nature Nanotechnology. 15, 256–271.","mla":"Grommet, Angela B., et al. “Chemical Reactivity under Nanoconfinement.” <i>Nature Nanotechnology</i>, vol. 15, Springer Nature, 2020, pp. 256–71, doi:<a href=\"https://doi.org/10.1038/s41565-020-0652-2\">10.1038/s41565-020-0652-2</a>.","apa":"Grommet, A. B., Feller, M., &#38; Klajn, R. (2020). Chemical reactivity under nanoconfinement. <i>Nature Nanotechnology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41565-020-0652-2\">https://doi.org/10.1038/s41565-020-0652-2</a>","chicago":"Grommet, Angela B., Moran Feller, and Rafal Klajn. “Chemical Reactivity under Nanoconfinement.” <i>Nature Nanotechnology</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41565-020-0652-2\">https://doi.org/10.1038/s41565-020-0652-2</a>.","short":"A.B. Grommet, M. Feller, R. Klajn, Nature Nanotechnology 15 (2020) 256–271.","ama":"Grommet AB, Feller M, Klajn R. Chemical reactivity under nanoconfinement. <i>Nature Nanotechnology</i>. 2020;15:256-271. doi:<a href=\"https://doi.org/10.1038/s41565-020-0652-2\">10.1038/s41565-020-0652-2</a>"},"quality_controlled":"1","extern":"1","pmid":1,"intvolume":"        15","year":"2020","publication_identifier":{"issn":["1748-3387"],"eissn":["1748-3395"]},"language":[{"iso":"eng"}],"page":"256-271","external_id":{"pmid":["32303705"]},"keyword":["Electrical and Electronic Engineering","Condensed Matter Physics","General Materials Science","Biomedical Engineering","Atomic and Molecular Physics","and Optics","Bioengineering"],"abstract":[{"lang":"eng","text":"Confining molecules can fundamentally change their chemical and physical properties. Confinement effects are considered instrumental at various stages of the origins of life, and life continues to rely on layers of compartmentalization to maintain an out-of-equilibrium state and efficiently synthesize complex biomolecules under mild conditions. As interest in synthetic confined systems grows, we are realizing that the principles governing reactivity under confinement are the same in abiological systems as they are in nature. In this Review, we categorize the ways in which nanoconfinement effects impact chemical reactivity in synthetic systems. Under nanoconfinement, chemical properties can be modulated to increase reaction rates, enhance selectivity and stabilize reactive species. Confinement effects also lead to changes in physical properties. The fluorescence of light emitters, the colours of dyes and electronic communication between electroactive species can all be tuned under confinement. Within each of these categories, we elucidate design principles and strategies that are widely applicable across a range of confined systems, specifically highlighting examples of different nanocompartments that influence reactivity in similar ways."}]},{"quality_controlled":"1","citation":{"mla":"Vampa, Giulio, et al. “Attosecond Synchronization of Extreme Ultraviolet High Harmonics from Crystals.” <i>Journal of Physics B: Atomic, Molecular and Optical Physics</i>, vol. 53, no. 14, 144003, IOP Publishing, 2020, doi:<a href=\"https://doi.org/10.1088/1361-6455/ab8e56\">10.1088/1361-6455/ab8e56</a>.","ieee":"G. Vampa <i>et al.</i>, “Attosecond synchronization of extreme ultraviolet high harmonics from crystals,” <i>Journal of Physics B: Atomic, Molecular and Optical Physics</i>, vol. 53, no. 14. IOP Publishing, 2020.","ista":"Vampa G, Lu J, You YS, Baykusheva DR, Wu M, Liu H, Schafer KJ, Gaarde MB, Reis DA, Ghimire S. 2020. Attosecond synchronization of extreme ultraviolet high harmonics from crystals. Journal of Physics B: Atomic, Molecular and Optical Physics. 53(14), 144003.","chicago":"Vampa, Giulio, Jian Lu, Yong Sing You, Denitsa Rangelova Baykusheva, Mengxi Wu, Hanzhe Liu, Kenneth J Schafer, Mette B Gaarde, David A Reis, and Shambhu Ghimire. “Attosecond Synchronization of Extreme Ultraviolet High Harmonics from Crystals.” <i>Journal of Physics B: Atomic, Molecular and Optical Physics</i>. IOP Publishing, 2020. <a href=\"https://doi.org/10.1088/1361-6455/ab8e56\">https://doi.org/10.1088/1361-6455/ab8e56</a>.","short":"G. Vampa, J. Lu, Y.S. You, D.R. Baykusheva, M. Wu, H. Liu, K.J. Schafer, M.B. Gaarde, D.A. Reis, S. Ghimire, Journal of Physics B: Atomic, Molecular and Optical Physics 53 (2020).","apa":"Vampa, G., Lu, J., You, Y. S., Baykusheva, D. R., Wu, M., Liu, H., … Ghimire, S. (2020). Attosecond synchronization of extreme ultraviolet high harmonics from crystals. <i>Journal of Physics B: Atomic, Molecular and Optical Physics</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1361-6455/ab8e56\">https://doi.org/10.1088/1361-6455/ab8e56</a>","ama":"Vampa G, Lu J, You YS, et al. Attosecond synchronization of extreme ultraviolet high harmonics from crystals. <i>Journal of Physics B: Atomic, Molecular and Optical Physics</i>. 2020;53(14). doi:<a href=\"https://doi.org/10.1088/1361-6455/ab8e56\">10.1088/1361-6455/ab8e56</a>"},"doi":"10.1088/1361-6455/ab8e56","extern":"1","arxiv":1,"intvolume":"        53","year":"2020","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0953-4075"],"eissn":["1361-6455"]},"external_id":{"arxiv":["2001.09951"]},"keyword":["Condensed Matter Physics","Atomic and Molecular Physics","and Optics"],"abstract":[{"text":"The interaction of strong near-infrared (NIR) laser pulses with wide-bandgap dielectrics produces high harmonics in the extreme ultraviolet (XUV) wavelength range. These observations have opened up the possibility of attosecond metrology in solids, which would benefit from a precise measurement of the emission times of individual harmonics with respect to the NIR laser field. Here we show that, when high-harmonics are detected from the input surface of a magnesium oxide crystal, a bichromatic probing of the XUV emission shows a clear synchronization largely consistent with a semiclassical model of electron–hole recollisions in bulk solids. On the other hand, the bichromatic spectrogram of harmonics originating from the exit surface of the 200 μm-thick crystal is strongly modified, indicating the influence of laser field distortions during propagation. Our tracking of sub-cycle electron and hole re-collisions at XUV energies is relevant to the development of solid-state sources of attosecond pulses.","lang":"eng"}],"oa":1,"author":[{"full_name":"Vampa, Giulio","last_name":"Vampa","first_name":"Giulio"},{"full_name":"Lu, Jian","first_name":"Jian","last_name":"Lu"},{"full_name":"You, Yong Sing","last_name":"You","first_name":"Yong Sing"},{"full_name":"Baykusheva, Denitsa Rangelova","last_name":"Baykusheva","id":"71b4d059-2a03-11ee-914d-dfa3beed6530","first_name":"Denitsa Rangelova"},{"full_name":"Wu, Mengxi","last_name":"Wu","first_name":"Mengxi"},{"full_name":"Liu, Hanzhe","first_name":"Hanzhe","last_name":"Liu"},{"first_name":"Kenneth J","last_name":"Schafer","full_name":"Schafer, Kenneth J"},{"last_name":"Gaarde","first_name":"Mette B","full_name":"Gaarde, Mette B"},{"first_name":"David A","last_name":"Reis","full_name":"Reis, David A"},{"full_name":"Ghimire, Shambhu","last_name":"Ghimire","first_name":"Shambhu"}],"oa_version":"Preprint","date_created":"2023-08-09T13:09:51Z","publication":"Journal of Physics B: Atomic, Molecular and Optical Physics","_id":"13998","type":"journal_article","article_processing_charge":"No","issue":"14","volume":53,"title":"Attosecond synchronization of extreme ultraviolet high harmonics from crystals","status":"public","article_number":"144003","day":"17","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2001.09951"}],"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2023-08-22T07:36:36Z","publisher":"IOP Publishing","article_type":"original","date_published":"2020-06-17T00:00:00Z","month":"06"},{"language":[{"iso":"eng"}],"publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"year":"2020","intvolume":"        16","extern":"1","citation":{"mla":"Biswas, Shubhadeep, et al. “Probing Molecular Environment through Photoemission Delays.” <i>Nature Physics</i>, vol. 16, no. 7, Springer Nature, 2020, pp. 778–83, doi:<a href=\"https://doi.org/10.1038/s41567-020-0887-8\">10.1038/s41567-020-0887-8</a>.","ista":"Biswas S, Förg B, Ortmann L, Schötz J, Schweinberger W, Zimmermann T, Pi L, Baykusheva DR, Masood HA, Liontos I, Kamal AM, Kling NG, Alharbi AF, Alharbi M, Azzeer AM, Hartmann G, Wörner HJ, Landsman AS, Kling MF. 2020. Probing molecular environment through photoemission delays. Nature Physics. 16(7), 778–783.","ieee":"S. Biswas <i>et al.</i>, “Probing molecular environment through photoemission delays,” <i>Nature Physics</i>, vol. 16, no. 7. Springer Nature, pp. 778–783, 2020.","chicago":"Biswas, Shubhadeep, Benjamin Förg, Lisa Ortmann, Johannes Schötz, Wolfgang Schweinberger, Tomáš Zimmermann, Liangwen Pi, et al. “Probing Molecular Environment through Photoemission Delays.” <i>Nature Physics</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41567-020-0887-8\">https://doi.org/10.1038/s41567-020-0887-8</a>.","short":"S. Biswas, B. Förg, L. Ortmann, J. Schötz, W. Schweinberger, T. Zimmermann, L. Pi, D.R. Baykusheva, H.A. Masood, I. Liontos, A.M. Kamal, N.G. Kling, A.F. Alharbi, M. Alharbi, A.M. Azzeer, G. Hartmann, H.J. Wörner, A.S. Landsman, M.F. Kling, Nature Physics 16 (2020) 778–783.","apa":"Biswas, S., Förg, B., Ortmann, L., Schötz, J., Schweinberger, W., Zimmermann, T., … Kling, M. F. (2020). Probing molecular environment through photoemission delays. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-020-0887-8\">https://doi.org/10.1038/s41567-020-0887-8</a>","ama":"Biswas S, Förg B, Ortmann L, et al. Probing molecular environment through photoemission delays. <i>Nature Physics</i>. 2020;16(7):778-783. doi:<a href=\"https://doi.org/10.1038/s41567-020-0887-8\">10.1038/s41567-020-0887-8</a>"},"doi":"10.1038/s41567-020-0887-8","quality_controlled":"1","abstract":[{"text":"Attosecond chronoscopy has revealed small but measurable delays in photoionization, characterized by the ejection of an electron on absorption of a single photon. Ionization-delay measurements in atomic targets provide a wealth of information about the timing of the photoelectric effect, resonances, electron correlations and transport. However, extending this approach to molecules presents challenges, such as identifying the correct ionization channels and the effect of the anisotropic molecular landscape on the measured delays. Here, we measure ionization delays from ethyl iodide around a giant dipole resonance. By using the theoretical value for the iodine atom as a reference, we disentangle the contribution from the functional ethyl group, which is responsible for the characteristic chemical reactivity of a molecule. We find a substantial additional delay caused by the presence of a functional group, which encodes the effect of the molecular potential on the departing electron. Such information is inaccessible to the conventional approach of measuring photoionization cross-sections. The results establish ionization-delay measurements as a valuable tool in investigating the electronic properties of molecules.","lang":"eng"}],"keyword":["General Physics and Astronomy"],"page":"778-783","day":"01","status":"public","volume":16,"title":"Probing molecular environment through photoemission delays","issue":"7","type":"journal_article","article_processing_charge":"No","_id":"13999","publication":"Nature Physics","date_created":"2023-08-09T13:10:07Z","oa_version":"None","author":[{"last_name":"Biswas","first_name":"Shubhadeep","full_name":"Biswas, Shubhadeep"},{"last_name":"Förg","first_name":"Benjamin","full_name":"Förg, Benjamin"},{"last_name":"Ortmann","first_name":"Lisa","full_name":"Ortmann, Lisa"},{"full_name":"Schötz, Johannes","first_name":"Johannes","last_name":"Schötz"},{"full_name":"Schweinberger, Wolfgang","last_name":"Schweinberger","first_name":"Wolfgang"},{"full_name":"Zimmermann, Tomáš","first_name":"Tomáš","last_name":"Zimmermann"},{"full_name":"Pi, Liangwen","last_name":"Pi","first_name":"Liangwen"},{"full_name":"Baykusheva, Denitsa Rangelova","last_name":"Baykusheva","first_name":"Denitsa Rangelova","id":"71b4d059-2a03-11ee-914d-dfa3beed6530"},{"first_name":"Hafiz A.","last_name":"Masood","full_name":"Masood, Hafiz A."},{"full_name":"Liontos, Ioannis","first_name":"Ioannis","last_name":"Liontos"},{"last_name":"Kamal","first_name":"Amgad M.","full_name":"Kamal, Amgad M."},{"first_name":"Nora G.","last_name":"Kling","full_name":"Kling, Nora G."},{"first_name":"Abdullah F.","last_name":"Alharbi","full_name":"Alharbi, Abdullah F."},{"full_name":"Alharbi, Meshaal","first_name":"Meshaal","last_name":"Alharbi"},{"full_name":"Azzeer, Abdallah M.","first_name":"Abdallah M.","last_name":"Azzeer"},{"last_name":"Hartmann","first_name":"Gregor","full_name":"Hartmann, Gregor"},{"first_name":"Hans J.","last_name":"Wörner","full_name":"Wörner, Hans J."},{"full_name":"Landsman, Alexandra S.","first_name":"Alexandra S.","last_name":"Landsman"},{"last_name":"Kling","first_name":"Matthias F.","full_name":"Kling, Matthias F."}],"month":"07","date_published":"2020-07-01T00:00:00Z","article_type":"original","publisher":"Springer Nature","date_updated":"2023-08-22T07:38:04Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","scopus_import":"1"},{"main_file_link":[{"url":"https://www.biorxiv.org/content/10.1101/2020.05.01.071761v1","open_access":"1"}],"scopus_import":"1","month":"10","date_published":"2020-10-06T00:00:00Z","article_type":"original","publisher":"Royal Society of Chemistry","date_updated":"2021-11-26T07:00:33Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","publication_status":"published","_id":"10341","type":"journal_article","issue":"47","article_processing_charge":"No","publication":"Soft Matter","oa_version":"Published Version","date_created":"2021-11-26T06:29:41Z","author":[{"first_name":"V. E.","last_name":"Debets","full_name":"Debets, V. E."},{"full_name":"Janssen, L. M. C.","last_name":"Janssen","first_name":"L. M. C."},{"id":"bf63d406-f056-11eb-b41d-f263a6566d8b","first_name":"Anđela","last_name":"Šarić","full_name":"Šarić, Anđela","orcid":"0000-0002-7854-2139"}],"day":"06","status":"public","volume":16,"title":"Characterising the diffusion of biological nanoparticles on fluid and cross-linked membranes","external_id":{"pmid":["33084724"]},"page":"10628-10639","oa":1,"keyword":["condensed matter physics","general chemistry"],"abstract":[{"text":"Tracing the motion of macromolecules, viruses, and nanoparticles adsorbed onto cell membranes is currently the most direct way of probing the complex dynamic interactions behind vital biological processes, including cell signalling, trafficking, and viral infection. The resulting trajectories are usually consistent with some type of anomalous diffusion, but the molecular origins behind the observed anomalous behaviour are usually not obvious. Here we use coarse-grained molecular dynamics simulations to help identify the physical mechanisms that can give rise to experimentally observed trajectories of nanoscopic objects moving on biological membranes. We find that diffusion on membranes of high fluidities typically results in normal diffusion of the adsorbed nanoparticle, irrespective of the concentration of receptors, receptor clustering, or multivalent interactions between the particle and membrane receptors. Gel-like membranes on the other hand result in anomalous diffusion of the particle, which becomes more pronounced at higher receptor concentrations. This anomalous diffusion is characterised by local particle trapping in the regions of high receptor concentrations and fast hopping between such regions. The normal diffusion is recovered in the limit where the gel membrane is saturated with receptors. We conclude that hindered receptor diffusivity can be a common reason behind the observed anomalous diffusion of viruses, vesicles, and nanoparticles adsorbed on cell and model membranes. Our results enable direct comparison with experiments and offer a new route for interpreting motility experiments on cell membranes.","lang":"eng"}],"extern":"1","doi":"10.1039/d0sm00712a","citation":{"short":"V.E. Debets, L.M.C. Janssen, A. Šarić, Soft Matter 16 (2020) 10628–10639.","chicago":"Debets, V. E., L. M. C. Janssen, and Anđela Šarić. “Characterising the Diffusion of Biological Nanoparticles on Fluid and Cross-Linked Membranes.” <i>Soft Matter</i>. Royal Society of Chemistry, 2020. <a href=\"https://doi.org/10.1039/d0sm00712a\">https://doi.org/10.1039/d0sm00712a</a>.","apa":"Debets, V. E., Janssen, L. M. C., &#38; Šarić, A. (2020). Characterising the diffusion of biological nanoparticles on fluid and cross-linked membranes. <i>Soft Matter</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d0sm00712a\">https://doi.org/10.1039/d0sm00712a</a>","mla":"Debets, V. E., et al. “Characterising the Diffusion of Biological Nanoparticles on Fluid and Cross-Linked Membranes.” <i>Soft Matter</i>, vol. 16, no. 47, Royal Society of Chemistry, 2020, pp. 10628–39, doi:<a href=\"https://doi.org/10.1039/d0sm00712a\">10.1039/d0sm00712a</a>.","ieee":"V. E. Debets, L. M. C. Janssen, and A. Šarić, “Characterising the diffusion of biological nanoparticles on fluid and cross-linked membranes,” <i>Soft Matter</i>, vol. 16, no. 47. Royal Society of Chemistry, pp. 10628–10639, 2020.","ista":"Debets VE, Janssen LMC, Šarić A. 2020. Characterising the diffusion of biological nanoparticles on fluid and cross-linked membranes. Soft Matter. 16(47), 10628–10639.","ama":"Debets VE, Janssen LMC, Šarić A. Characterising the diffusion of biological nanoparticles on fluid and cross-linked membranes. <i>Soft Matter</i>. 2020;16(47):10628-10639. doi:<a href=\"https://doi.org/10.1039/d0sm00712a\">10.1039/d0sm00712a</a>"},"quality_controlled":"1","acknowledgement":"We thank Jessica McQuade for her input at the start of the project. We acknowledge support from the ERASMUS Placement Programme (V. E. D.), the UCL Institute for the Physics of Living Systems (V. E. D. and A. Š.), the UCL Global Engagement Fund (L. M. C. J.), and the Royal Society (A. Š.).","language":[{"iso":"eng"}],"publication_identifier":{"issn":["1744-683X","1744-6848"]},"year":"2020","pmid":1,"intvolume":"        16"}]