[{"ddc":["540"],"acknowledgement":"We thank Stefan Wiedemann for the synthesis of reference compounds and Pia Heinrichs for assistance in the NMR measurements of the oligonucleotides. We also thank Dr. Luis Escobar and Jonas Feldmann for valued discussions. This work was supported by the German Research Foundation (DFG) for financial support via CRC1309 (Project ID 325871075, A04), CRC1361 (Project ID 893547839, P02) and CRC1032 (Project ID 201269156, A5). This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program under grant agreement No 741912 (EpiR). We are grateful for additional funding from the Volkswagen Foundation (EvoRib). Open Access funding enabled and organized by Projekt DEAL.","volume":61,"abstract":[{"lang":"eng","text":"The question of how RNA, as the principal carrier of genetic information evolved is fundamentally important for our understanding of the origin of life. The RNA molecule is far too complex to have formed in one evolutionary step, suggesting that ancestral proto-RNAs (first ancestor of RNA) may have existed, which evolved over time into the RNA of today. Here we show that isoxazole nucleosides, which are quickly formed from hydroxylamine, cyanoacetylene, urea and ribose, are plausible precursors for RNA. The isoxazole nucleoside can rearrange within an RNA-strand to give cytidine, which leads to an increase of pairing stability. If the proto-RNA contains a canonical seed-nucleoside with defined stereochemistry, the seed-nucleoside can control the configuration of the anomeric center that forms during the in-RNA transformation. The results demonstrate that RNA could have emerged from evolutionarily primitive precursor isoxazole ribosides after strand formation."}],"day":"07","doi":"10.1002/anie.202211945","external_id":{"isi":["000866428500001"]},"isi":1,"citation":{"chicago":"Xu, Felix, Antony Crisp, Thea Schinkel, Romeo C. A. Dubini, Sarah Hübner, Sidney Becker, Florian Schelter, Petra Rovo, and Thomas Carell. “Isoxazole Nucleosides as Building Blocks for a Plausible Proto‐RNA.” <i>Angewandte Chemie International Edition</i>. Wiley, 2022. <a href=\"https://doi.org/10.1002/anie.202211945\">https://doi.org/10.1002/anie.202211945</a>.","ieee":"F. Xu <i>et al.</i>, “Isoxazole nucleosides as building blocks for a plausible proto‐RNA,” <i>Angewandte Chemie International Edition</i>, vol. 61, no. 45. Wiley, 2022.","apa":"Xu, F., Crisp, A., Schinkel, T., Dubini, R. C. A., Hübner, S., Becker, S., … Carell, T. (2022). Isoxazole nucleosides as building blocks for a plausible proto‐RNA. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202211945\">https://doi.org/10.1002/anie.202211945</a>","ama":"Xu F, Crisp A, Schinkel T, et al. Isoxazole nucleosides as building blocks for a plausible proto‐RNA. <i>Angewandte Chemie International Edition</i>. 2022;61(45). doi:<a href=\"https://doi.org/10.1002/anie.202211945\">10.1002/anie.202211945</a>","ista":"Xu F, Crisp A, Schinkel T, Dubini RCA, Hübner S, Becker S, Schelter F, Rovo P, Carell T. 2022. Isoxazole nucleosides as building blocks for a plausible proto‐RNA. Angewandte Chemie International Edition. 61(45), e202211945.","short":"F. Xu, A. Crisp, T. Schinkel, R.C.A. Dubini, S. Hübner, S. Becker, F. Schelter, P. Rovo, T. Carell, Angewandte Chemie International Edition 61 (2022).","mla":"Xu, Felix, et al. “Isoxazole Nucleosides as Building Blocks for a Plausible Proto‐RNA.” <i>Angewandte Chemie International Edition</i>, vol. 61, no. 45, e202211945, Wiley, 2022, doi:<a href=\"https://doi.org/10.1002/anie.202211945\">10.1002/anie.202211945</a>."},"year":"2022","date_updated":"2023-08-04T09:32:42Z","article_type":"original","publisher":"Wiley","file_date_updated":"2023-01-27T10:28:45Z","quality_controlled":"1","intvolume":"        61","title":"Isoxazole nucleosides as building blocks for a plausible proto‐RNA","department":[{"_id":"NMR"}],"article_processing_charge":"No","date_created":"2023-01-16T09:49:05Z","publication_status":"published","issue":"45","author":[{"first_name":"Felix","last_name":"Xu","full_name":"Xu, Felix"},{"first_name":"Antony","last_name":"Crisp","full_name":"Crisp, Antony"},{"last_name":"Schinkel","first_name":"Thea","full_name":"Schinkel, Thea"},{"full_name":"Dubini, Romeo C. A.","last_name":"Dubini","first_name":"Romeo C. A."},{"first_name":"Sarah","last_name":"Hübner","full_name":"Hübner, Sarah"},{"full_name":"Becker, Sidney","first_name":"Sidney","last_name":"Becker"},{"first_name":"Florian","last_name":"Schelter","full_name":"Schelter, Florian"},{"id":"c316e53f-b965-11eb-b128-bb26acc59c00","first_name":"Petra","last_name":"Rovo","orcid":"0000-0001-8729-7326","full_name":"Rovo, Petra"},{"full_name":"Carell, Thomas","last_name":"Carell","first_name":"Thomas"}],"scopus_import":"1","_id":"12228","status":"public","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","file":[{"file_id":"12422","creator":"dernst","relation":"main_file","success":1,"access_level":"open_access","date_updated":"2023-01-27T10:28:45Z","content_type":"application/pdf","file_name":"2022_AngewandteChemieInternat_Xu.pdf","date_created":"2023-01-27T10:28:45Z","file_size":1076715,"checksum":"4e8152454d12025d13f6e6e9ca06b5d0"}],"oa":1,"publication_identifier":{"issn":["1433-7851"],"eissn":["1521-3773"]},"type":"journal_article","date_published":"2022-11-07T00:00:00Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"keyword":["General Chemistry","Catalysis"],"language":[{"iso":"eng"}],"article_number":"e202211945","month":"11","oa_version":"Published Version","has_accepted_license":"1","publication":"Angewandte Chemie International Edition"},{"month":"09","oa_version":"Published Version","project":[{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385","name":"International IST Doctoral Program"}],"publication":"Chemistry of Materials","has_accepted_license":"1","language":[{"iso":"eng"}],"keyword":["Materials Chemistry","General Chemical Engineering","General Chemistry"],"oa":1,"publication_identifier":{"issn":["0897-4756"],"eissn":["1520-5002"]},"date_published":"2022-09-20T00:00:00Z","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","related_material":{"record":[{"status":"public","id":"12885","relation":"dissertation_contains"}]},"file":[{"content_type":"application/pdf","file_name":"2022_ChemistryMaterials_Fiedler.pdf","date_updated":"2023-01-30T07:35:09Z","file_size":10923495,"checksum":"f7143e44ab510519d1949099c3558532","date_created":"2023-01-30T07:35:09Z","creator":"dernst","file_id":"12434","access_level":"open_access","relation":"main_file","success":1}],"title":"Solution-processed inorganic thermoelectric materials: Opportunities and challenges","intvolume":"        34","publication_status":"published","date_created":"2023-01-16T09:51:26Z","department":[{"_id":"MaIb"}],"article_processing_charge":"Yes (via OA deal)","author":[{"full_name":"Fiedler, Christine","first_name":"Christine","last_name":"Fiedler","id":"bd3fceba-dc74-11ea-a0a7-c17f71817366"},{"id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425","full_name":"Kleinhanns, Tobias","first_name":"Tobias","last_name":"Kleinhanns"},{"first_name":"Maria","last_name":"Garcia","full_name":"Garcia, Maria","id":"6e5c50b8-97dc-11ed-be98-b0a74c84cae0"},{"id":"BB243B88-D767-11E9-B658-BC13E6697425","last_name":"Lee","first_name":"Seungho","full_name":"Lee, Seungho","orcid":"0000-0002-6962-8598"},{"full_name":"Calcabrini, Mariano","last_name":"Calcabrini","first_name":"Mariano","id":"45D7531A-F248-11E8-B48F-1D18A9856A87"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","last_name":"Ibáñez","first_name":"Maria"}],"issue":"19","_id":"12237","pmid":1,"scopus_import":"1","article_type":"original","publisher":"American Chemical Society","file_date_updated":"2023-01-30T07:35:09Z","page":"8471-8489","ec_funded":1,"quality_controlled":"1","abstract":[{"lang":"eng","text":"Thermoelectric technology requires synthesizing complex materials where not only the crystal structure but also other structural features such as defects, grain size and orientation, and interfaces must be controlled. To date, conventional solid-state techniques are unable to provide this level of control. Herein, we present a synthetic approach in which dense inorganic thermoelectric materials are produced by the consolidation of well-defined nanoparticle powders. The idea is that controlling the characteristics of the powder allows the chemical transformations that take place during consolidation to be guided, ultimately yielding inorganic solids with targeted features. Different from conventional methods, syntheses in solution can produce particles with unprecedented control over their size, shape, crystal structure, composition, and surface chemistry. However, to date, most works have focused only on the low-cost benefits of this strategy. In this perspective, we first cover the opportunities that solution processing of the powder offers, emphasizing the potential structural features that can be controlled by precisely engineering the inorganic core of the particle, the surface, and the organization of the particles before consolidation. We then discuss the challenges of this synthetic approach and more practical matters related to solution processing. Finally, we suggest some good practices for adequate knowledge transfer and improving reproducibility among different laboratories."}],"doi":"10.1021/acs.chemmater.2c01967","day":"20","isi":1,"external_id":{"pmid":["36248227"],"isi":["000917837600001"]},"date_updated":"2023-08-04T09:38:26Z","year":"2022","citation":{"ista":"Fiedler C, Kleinhanns T, Garcia M, Lee S, Calcabrini M, Ibáñez M. 2022. Solution-processed inorganic thermoelectric materials: Opportunities and challenges. Chemistry of Materials. 34(19), 8471–8489.","short":"C. Fiedler, T. Kleinhanns, M. Garcia, S. Lee, M. Calcabrini, M. Ibáñez, Chemistry of Materials 34 (2022) 8471–8489.","mla":"Fiedler, Christine, et al. “Solution-Processed Inorganic Thermoelectric Materials: Opportunities and Challenges.” <i>Chemistry of Materials</i>, vol. 34, no. 19, American Chemical Society, 2022, pp. 8471–89, doi:<a href=\"https://doi.org/10.1021/acs.chemmater.2c01967\">10.1021/acs.chemmater.2c01967</a>.","chicago":"Fiedler, Christine, Tobias Kleinhanns, Maria Garcia, Seungho Lee, Mariano Calcabrini, and Maria Ibáñez. “Solution-Processed Inorganic Thermoelectric Materials: Opportunities and Challenges.” <i>Chemistry of Materials</i>. American Chemical Society, 2022. <a href=\"https://doi.org/10.1021/acs.chemmater.2c01967\">https://doi.org/10.1021/acs.chemmater.2c01967</a>.","ieee":"C. Fiedler, T. Kleinhanns, M. Garcia, S. Lee, M. Calcabrini, and M. Ibáñez, “Solution-processed inorganic thermoelectric materials: Opportunities and challenges,” <i>Chemistry of Materials</i>, vol. 34, no. 19. American Chemical Society, pp. 8471–8489, 2022.","ama":"Fiedler C, Kleinhanns T, Garcia M, Lee S, Calcabrini M, Ibáñez M. Solution-processed inorganic thermoelectric materials: Opportunities and challenges. <i>Chemistry of Materials</i>. 2022;34(19):8471-8489. doi:<a href=\"https://doi.org/10.1021/acs.chemmater.2c01967\">10.1021/acs.chemmater.2c01967</a>","apa":"Fiedler, C., Kleinhanns, T., Garcia, M., Lee, S., Calcabrini, M., &#38; Ibáñez, M. (2022). Solution-processed inorganic thermoelectric materials: Opportunities and challenges. <i>Chemistry of Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.chemmater.2c01967\">https://doi.org/10.1021/acs.chemmater.2c01967</a>"},"ddc":["540"],"volume":34,"acknowledgement":"This work was financially supported by ISTA and the Werner Siemens Foundation. M.C. has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement no. 665385."},{"month":"10","oa_version":"Published Version","publication":"ACS Catalysis","language":[{"iso":"eng"}],"keyword":["Catalysis","General Chemistry"],"oa":1,"publication_identifier":{"eissn":["2155-5435"]},"date_published":"2022-10-27T00:00:00Z","type":"journal_article","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1021/acscatal.2c04025"}],"title":"Modulating the surface and photophysical properties of carbon dots to access colloidal photocatalysts for cross-couplings","intvolume":"        12","publication_status":"published","date_created":"2023-05-08T08:28:54Z","article_processing_charge":"No","author":[{"last_name":"Zhao","first_name":"Zhouxiang","full_name":"Zhao, Zhouxiang"},{"first_name":"Bartholomäus","last_name":"Pieber","orcid":"0000-0001-8689-388X","full_name":"Pieber, Bartholomäus","id":"93e5e5b2-0da6-11ed-8a41-af589a024726"},{"full_name":"Delbianco, Martina","first_name":"Martina","last_name":"Delbianco"}],"issue":"22","_id":"12923","scopus_import":"1","article_type":"original","publisher":"American Chemical Society","page":"13831-13837","quality_controlled":"1","abstract":[{"text":"Photoredox-mediated Ni-catalyzed cross-couplings are powerful transformations to form carbon–heteroatom bonds and are generally photocatalyzed by noble metal complexes. Low-cost and easy-to-prepare carbon dots (CDs) are attractive quasi-homogeneous photocatalyst alternatives, but their applicability is limited by their short photoluminescence (PL) lifetimes. By tuning the surface and PL properties of CDs, we designed colloidal CD nano-photocatalysts for a broad range of Ni-mediated cross-couplings between aryl halides and nucleophiles. In particular, a CD decorated with amino groups permitted coupling to a wide range of aryl halides and thiols under mild, base-free conditions. Mechanistic studies suggested dynamic quenching of the CD excited state by the Ni co-catalyst and identified that pyridinium iodide (pyHI), a previously used additive in metallaphotocatalyzed cross-couplings, can also act as a photocatalyst in such transformations.","lang":"eng"}],"doi":"10.1021/acscatal.2c04025","day":"27","date_updated":"2023-05-15T08:30:13Z","year":"2022","citation":{"ista":"Zhao Z, Pieber B, Delbianco M. 2022. Modulating the surface and photophysical properties of carbon dots to access colloidal photocatalysts for cross-couplings. ACS Catalysis. 12(22), 13831–13837.","mla":"Zhao, Zhouxiang, et al. “Modulating the Surface and Photophysical Properties of Carbon Dots to Access Colloidal Photocatalysts for Cross-Couplings.” <i>ACS Catalysis</i>, vol. 12, no. 22, American Chemical Society, 2022, pp. 13831–37, doi:<a href=\"https://doi.org/10.1021/acscatal.2c04025\">10.1021/acscatal.2c04025</a>.","short":"Z. Zhao, B. Pieber, M. Delbianco, ACS Catalysis 12 (2022) 13831–13837.","ieee":"Z. Zhao, B. Pieber, and M. Delbianco, “Modulating the surface and photophysical properties of carbon dots to access colloidal photocatalysts for cross-couplings,” <i>ACS Catalysis</i>, vol. 12, no. 22. American Chemical Society, pp. 13831–13837, 2022.","chicago":"Zhao, Zhouxiang, Bartholomäus Pieber, and Martina Delbianco. “Modulating the Surface and Photophysical Properties of Carbon Dots to Access Colloidal Photocatalysts for Cross-Couplings.” <i>ACS Catalysis</i>. American Chemical Society, 2022. <a href=\"https://doi.org/10.1021/acscatal.2c04025\">https://doi.org/10.1021/acscatal.2c04025</a>.","ama":"Zhao Z, Pieber B, Delbianco M. Modulating the surface and photophysical properties of carbon dots to access colloidal photocatalysts for cross-couplings. <i>ACS Catalysis</i>. 2022;12(22):13831-13837. doi:<a href=\"https://doi.org/10.1021/acscatal.2c04025\">10.1021/acscatal.2c04025</a>","apa":"Zhao, Z., Pieber, B., &#38; Delbianco, M. (2022). Modulating the surface and photophysical properties of carbon dots to access colloidal photocatalysts for cross-couplings. <i>ACS Catalysis</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acscatal.2c04025\">https://doi.org/10.1021/acscatal.2c04025</a>"},"extern":"1","volume":12},{"day":"14","doi":"10.1002/anie.202211433","abstract":[{"text":"We demonstrate that several visible-light-mediated carbon−heteroatom cross-coupling reactions can be carried out using a photoactive NiII precatalyst that forms in situ from a nickel salt and a bipyridine ligand decorated with two carbazole groups (Ni(Czbpy)Cl2). The activation of this precatalyst towards cross-coupling reactions follows a hitherto undisclosed mechanism that is different from previously reported light-responsive nickel complexes that undergo metal-to-ligand charge transfer. Theoretical and spectroscopic investigations revealed that irradiation of Ni(Czbpy)Cl2 with visible light causes an initial intraligand charge transfer event that triggers productive catalysis. Ligand polymerization affords a porous, recyclable organic polymer for heterogeneous nickel catalysis of cross-coupling reactions. The heterogeneous catalyst shows stable performance in a packed-bed flow reactor during a week of continuous operation.","lang":"eng"}],"citation":{"apa":"Cavedon, C., Gisbertz, S., Reischauer, S., Vogl, S., Sperlich, E., Burke, J. H., … Pieber, B. (2022). Intraligand charge transfer enables visible‐light‐mediated Nickel‐catalyzed cross-coupling reactions. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202211433\">https://doi.org/10.1002/anie.202211433</a>","ama":"Cavedon C, Gisbertz S, Reischauer S, et al. Intraligand charge transfer enables visible‐light‐mediated Nickel‐catalyzed cross-coupling reactions. <i>Angewandte Chemie International Edition</i>. 2022;61(46). doi:<a href=\"https://doi.org/10.1002/anie.202211433\">10.1002/anie.202211433</a>","ieee":"C. Cavedon <i>et al.</i>, “Intraligand charge transfer enables visible‐light‐mediated Nickel‐catalyzed cross-coupling reactions,” <i>Angewandte Chemie International Edition</i>, vol. 61, no. 46. Wiley, 2022.","chicago":"Cavedon, Cristian, Sebastian Gisbertz, Susanne Reischauer, Sarah Vogl, Eric Sperlich, John H. Burke, Rachel F. Wallick, et al. “Intraligand Charge Transfer Enables Visible‐light‐mediated Nickel‐catalyzed Cross-Coupling Reactions.” <i>Angewandte Chemie International Edition</i>. Wiley, 2022. <a href=\"https://doi.org/10.1002/anie.202211433\">https://doi.org/10.1002/anie.202211433</a>.","short":"C. Cavedon, S. Gisbertz, S. Reischauer, S. Vogl, E. Sperlich, J.H. Burke, R.F. Wallick, S. Schrottke, W. Hsu, L. Anghileri, Y. Pfeifer, N. Richter, C. Teutloff, H. Müller‐Werkmeister, D. Cambié, P.H. Seeberger, J. Vura‐Weis, R.M. van der Veen, A. Thomas, B. Pieber, Angewandte Chemie International Edition 61 (2022).","mla":"Cavedon, Cristian, et al. “Intraligand Charge Transfer Enables Visible‐light‐mediated Nickel‐catalyzed Cross-Coupling Reactions.” <i>Angewandte Chemie International Edition</i>, vol. 61, no. 46, e202211433, Wiley, 2022, doi:<a href=\"https://doi.org/10.1002/anie.202211433\">10.1002/anie.202211433</a>.","ista":"Cavedon C, Gisbertz S, Reischauer S, Vogl S, Sperlich E, Burke JH, Wallick RF, Schrottke S, Hsu W, Anghileri L, Pfeifer Y, Richter N, Teutloff C, Müller‐Werkmeister H, Cambié D, Seeberger PH, Vura‐Weis J, van der Veen RM, Thomas A, Pieber B. 2022. Intraligand charge transfer enables visible‐light‐mediated Nickel‐catalyzed cross-coupling reactions. Angewandte Chemie International Edition. 61(46), e202211433."},"year":"2022","date_updated":"2023-05-15T08:27:25Z","volume":61,"extern":"1","date_created":"2023-05-08T08:30:11Z","article_processing_charge":"No","publication_status":"published","intvolume":"        61","title":"Intraligand charge transfer enables visible‐light‐mediated Nickel‐catalyzed cross-coupling reactions","scopus_import":"1","_id":"12924","issue":"46","author":[{"first_name":"Cristian","last_name":"Cavedon","full_name":"Cavedon, Cristian"},{"full_name":"Gisbertz, Sebastian","last_name":"Gisbertz","first_name":"Sebastian"},{"full_name":"Reischauer, Susanne","first_name":"Susanne","last_name":"Reischauer"},{"first_name":"Sarah","last_name":"Vogl","full_name":"Vogl, Sarah"},{"full_name":"Sperlich, Eric","last_name":"Sperlich","first_name":"Eric"},{"full_name":"Burke, John H.","last_name":"Burke","first_name":"John H."},{"last_name":"Wallick","first_name":"Rachel F.","full_name":"Wallick, Rachel F."},{"last_name":"Schrottke","first_name":"Stefanie","full_name":"Schrottke, Stefanie"},{"full_name":"Hsu, Wei‐Hsin","first_name":"Wei‐Hsin","last_name":"Hsu"},{"full_name":"Anghileri, Lucia","last_name":"Anghileri","first_name":"Lucia"},{"full_name":"Pfeifer, Yannik","last_name":"Pfeifer","first_name":"Yannik"},{"last_name":"Richter","first_name":"Noah","full_name":"Richter, Noah"},{"full_name":"Teutloff, Christian","first_name":"Christian","last_name":"Teutloff"},{"last_name":"Müller‐Werkmeister","first_name":"Henrike","full_name":"Müller‐Werkmeister, Henrike"},{"full_name":"Cambié, Dario","first_name":"Dario","last_name":"Cambié"},{"full_name":"Seeberger, Peter H.","first_name":"Peter H.","last_name":"Seeberger"},{"full_name":"Vura‐Weis, Josh","last_name":"Vura‐Weis","first_name":"Josh"},{"full_name":"van der Veen, Renske M.","last_name":"van der Veen","first_name":"Renske M."},{"full_name":"Thomas, Arne","last_name":"Thomas","first_name":"Arne"},{"id":"93e5e5b2-0da6-11ed-8a41-af589a024726","first_name":"Bartholomäus","last_name":"Pieber","orcid":"0000-0001-8689-388X","full_name":"Pieber, Bartholomäus"}],"publisher":"Wiley","article_type":"original","quality_controlled":"1","publication_identifier":{"eissn":["1521-3773"],"issn":["1433-7851"]},"oa":1,"type":"journal_article","date_published":"2022-11-14T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.1002/anie.202211433","open_access":"1"}],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","article_number":"e202211433","month":"11","publication":"Angewandte Chemie International Edition","keyword":["General Chemistry","Catalysis"],"language":[{"iso":"eng"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","main_file_link":[{"url":"https://doi.org/10.1038/s41557-021-00752-9","open_access":"1"}],"date_published":"2021-10-01T00:00:00Z","type":"journal_article","oa":1,"publication_identifier":{"issn":["1755-4330"],"eissn":["1755-4349"]},"language":[{"iso":"eng"}],"keyword":["General Chemical Engineering","General Chemistry"],"publication":"Nature Chemistry","month":"10","oa_version":"Published Version","extern":"1","volume":13,"external_id":{"pmid":["34489564"]},"date_updated":"2023-08-02T10:55:29Z","year":"2021","citation":{"ista":"Bian T, Gardin A, Gemen J, Houben L, Perego C, Lee B, Elad N, Chu Z, Pavan GM, Klajn R. 2021. Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures. Nature Chemistry. 13(10), 940–949.","short":"T. Bian, A. Gardin, J. Gemen, L. Houben, C. Perego, B. Lee, N. Elad, Z. Chu, G.M. Pavan, R. Klajn, Nature Chemistry 13 (2021) 940–949.","mla":"Bian, Tong, et al. “Electrostatic Co-Assembly of Nanoparticles with Oppositely Charged Small Molecules into Static and Dynamic Superstructures.” <i>Nature Chemistry</i>, vol. 13, no. 10, Springer Nature, 2021, pp. 940–49, doi:<a href=\"https://doi.org/10.1038/s41557-021-00752-9\">10.1038/s41557-021-00752-9</a>.","ieee":"T. Bian <i>et al.</i>, “Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures,” <i>Nature Chemistry</i>, vol. 13, no. 10. Springer Nature, pp. 940–949, 2021.","chicago":"Bian, Tong, Andrea Gardin, Julius Gemen, Lothar Houben, Claudio Perego, Byeongdu Lee, Nadav Elad, Zonglin Chu, Giovanni M. Pavan, and Rafal Klajn. “Electrostatic Co-Assembly of Nanoparticles with Oppositely Charged Small Molecules into Static and Dynamic Superstructures.” <i>Nature Chemistry</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41557-021-00752-9\">https://doi.org/10.1038/s41557-021-00752-9</a>.","apa":"Bian, T., Gardin, A., Gemen, J., Houben, L., Perego, C., Lee, B., … Klajn, R. (2021). Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures. <i>Nature Chemistry</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41557-021-00752-9\">https://doi.org/10.1038/s41557-021-00752-9</a>","ama":"Bian T, Gardin A, Gemen J, et al. Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures. <i>Nature Chemistry</i>. 2021;13(10):940-949. doi:<a href=\"https://doi.org/10.1038/s41557-021-00752-9\">10.1038/s41557-021-00752-9</a>"},"abstract":[{"text":"Coulombic interactions can be used to assemble charged nanoparticles into higher-order structures, but the process requires oppositely charged partners that are similarly sized. The ability to mediate the assembly of such charged nanoparticles using structurally simple small molecules would greatly facilitate the fabrication of nanostructured materials and harnessing their applications in catalysis, sensing and photonics. Here we show that small molecules with as few as three electric charges can effectively induce attractive interactions between oppositely charged nanoparticles in water. These interactions can guide the assembly of charged nanoparticles into colloidal crystals of a quality previously only thought to result from their co-crystallization with oppositely charged nanoparticles of a similar size. Transient nanoparticle assemblies can be generated using positively charged nanoparticles and multiply charged anions that are enzymatically hydrolysed into mono- and/or dianions. Our findings demonstrate an approach for the facile fabrication, manipulation and further investigation of static and dynamic nanostructured materials in aqueous environments.","lang":"eng"}],"doi":"10.1038/s41557-021-00752-9","day":"01","page":"940-949","quality_controlled":"1","article_type":"original","publisher":"Springer Nature","author":[{"full_name":"Bian, Tong","first_name":"Tong","last_name":"Bian"},{"full_name":"Gardin, Andrea","first_name":"Andrea","last_name":"Gardin"},{"full_name":"Gemen, Julius","last_name":"Gemen","first_name":"Julius"},{"last_name":"Houben","first_name":"Lothar","full_name":"Houben, Lothar"},{"last_name":"Perego","first_name":"Claudio","full_name":"Perego, Claudio"},{"last_name":"Lee","first_name":"Byeongdu","full_name":"Lee, Byeongdu"},{"first_name":"Nadav","last_name":"Elad","full_name":"Elad, Nadav"},{"first_name":"Zonglin","last_name":"Chu","full_name":"Chu, Zonglin"},{"full_name":"Pavan, Giovanni M.","last_name":"Pavan","first_name":"Giovanni M."},{"id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","last_name":"Klajn","first_name":"Rafal","full_name":"Klajn, Rafal"}],"issue":"10","_id":"13357","pmid":1,"scopus_import":"1","title":"Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures","intvolume":"        13","publication_status":"published","date_created":"2023-08-01T09:34:54Z","article_processing_charge":"No"},{"publication_identifier":{"issn":["1433-7851"],"eissn":["1521-3773"]},"oa":1,"type":"journal_article","date_published":"2021-03-08T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.1002/anie.202014963","open_access":"1"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","related_material":{"link":[{"relation":"erratum","url":"https://doi.org/10.1002/anie.202210394"}]},"oa_version":"Published Version","month":"03","publication":"Angewandte Chemie International Edition","keyword":["General Chemistry","Catalysis"],"language":[{"iso":"eng"}],"day":"08","doi":"10.1002/anie.202014963","abstract":[{"lang":"eng","text":"DNA nanotechnology offers a versatile toolbox for precise spatial and temporal manipulation of matter on the nanoscale. However, rendering DNA-based systems responsive to light has remained challenging. Herein, we describe the remote manipulation of native (non-photoresponsive) chiral plasmonic molecules (CPMs) using light. Our strategy is based on the use of a photoresponsive medium comprising a merocyanine-based photoacid. Upon exposure to visible light, the medium decreases its pH, inducing the formation of DNA triplex links, leading to a spatial reconfiguration of the CPMs. The process can be reversed simply by turning the light off and it can be repeated for multiple cycles. The degree of the overall chirality change in an ensemble of CPMs depends on the CPM fraction undergoing reconfiguration, which, remarkably, depends on and can be tuned by the intensity of incident light. Such a dynamic, remotely controlled system could aid in further advancing DNA-based devices and nanomaterials."}],"year":"2021","citation":{"ieee":"J. Ryssy <i>et al.</i>, “Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies,” <i>Angewandte Chemie International Edition</i>, vol. 60, no. 11. Wiley, pp. 5859–5863, 2021.","chicago":"Ryssy, Joonas, Ashwin K. Natarajan, Jinhua Wang, Arttu J. Lehtonen, Minh‐Kha Nguyen, Rafal Klajn, and Anton Kuzyk. “Light‐responsive Dynamic DNA‐origami‐based Plasmonic Assemblies.” <i>Angewandte Chemie International Edition</i>. Wiley, 2021. <a href=\"https://doi.org/10.1002/anie.202014963\">https://doi.org/10.1002/anie.202014963</a>.","apa":"Ryssy, J., Natarajan, A. K., Wang, J., Lehtonen, A. J., Nguyen, M., Klajn, R., &#38; Kuzyk, A. (2021). Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202014963\">https://doi.org/10.1002/anie.202014963</a>","ama":"Ryssy J, Natarajan AK, Wang J, et al. Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies. <i>Angewandte Chemie International Edition</i>. 2021;60(11):5859-5863. doi:<a href=\"https://doi.org/10.1002/anie.202014963\">10.1002/anie.202014963</a>","ista":"Ryssy J, Natarajan AK, Wang J, Lehtonen AJ, Nguyen M, Klajn R, Kuzyk A. 2021. Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies. Angewandte Chemie International Edition. 60(11), 5859–5863.","short":"J. Ryssy, A.K. Natarajan, J. Wang, A.J. Lehtonen, M. Nguyen, R. Klajn, A. Kuzyk, Angewandte Chemie International Edition 60 (2021) 5859–5863.","mla":"Ryssy, Joonas, et al. “Light‐responsive Dynamic DNA‐origami‐based Plasmonic Assemblies.” <i>Angewandte Chemie International Edition</i>, vol. 60, no. 11, Wiley, 2021, pp. 5859–63, doi:<a href=\"https://doi.org/10.1002/anie.202014963\">10.1002/anie.202014963</a>."},"date_updated":"2023-08-02T07:22:23Z","volume":60,"extern":"1","date_created":"2023-08-01T09:35:06Z","article_processing_charge":"No","publication_status":"published","intvolume":"        60","title":"Light‐responsive dynamic DNA‐origami‐based plasmonic assemblies","scopus_import":"1","_id":"13358","issue":"11","author":[{"last_name":"Ryssy","first_name":"Joonas","full_name":"Ryssy, Joonas"},{"full_name":"Natarajan, Ashwin K.","last_name":"Natarajan","first_name":"Ashwin K."},{"first_name":"Jinhua","last_name":"Wang","full_name":"Wang, Jinhua"},{"full_name":"Lehtonen, Arttu J.","first_name":"Arttu J.","last_name":"Lehtonen"},{"full_name":"Nguyen, Minh‐Kha","last_name":"Nguyen","first_name":"Minh‐Kha"},{"id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","last_name":"Klajn","first_name":"Rafal","full_name":"Klajn, Rafal"},{"first_name":"Anton","last_name":"Kuzyk","full_name":"Kuzyk, Anton"}],"publisher":"Wiley","article_type":"original","quality_controlled":"1","page":"5859-5863"},{"keyword":["Materials Chemistry","Biochemistry (medical)","General Chemical Engineering","Environmental Chemistry","Biochemistry","General Chemistry"],"language":[{"iso":"eng"}],"publication":"Chem","oa_version":"Published Version","month":"01","main_file_link":[{"url":"https://doi.org/10.1016/j.chempr.2020.11.025","open_access":"1"}],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","date_published":"2021-01-14T00:00:00Z","publication_identifier":{"issn":["2451-9294"]},"oa":1,"quality_controlled":"1","page":"23-37","publisher":"Elsevier","article_type":"original","scopus_import":"1","_id":"13359","issue":"1","author":[{"first_name":"Maren","last_name":"Weißenfels","full_name":"Weißenfels, Maren"},{"last_name":"Gemen","first_name":"Julius","full_name":"Gemen, Julius"},{"id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","full_name":"Klajn, Rafal","last_name":"Klajn","first_name":"Rafal"}],"date_created":"2023-08-01T09:35:19Z","article_processing_charge":"No","publication_status":"published","intvolume":"         7","title":"Dissipative self-assembly: Fueling with chemicals versus light","volume":7,"extern":"1","citation":{"apa":"Weißenfels, M., Gemen, J., &#38; Klajn, R. (2021). Dissipative self-assembly: Fueling with chemicals versus light. <i>Chem</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.chempr.2020.11.025\">https://doi.org/10.1016/j.chempr.2020.11.025</a>","ama":"Weißenfels M, Gemen J, Klajn R. Dissipative self-assembly: Fueling with chemicals versus light. <i>Chem</i>. 2021;7(1):23-37. doi:<a href=\"https://doi.org/10.1016/j.chempr.2020.11.025\">10.1016/j.chempr.2020.11.025</a>","ieee":"M. Weißenfels, J. Gemen, and R. Klajn, “Dissipative self-assembly: Fueling with chemicals versus light,” <i>Chem</i>, vol. 7, no. 1. Elsevier, pp. 23–37, 2021.","chicago":"Weißenfels, Maren, Julius Gemen, and Rafal Klajn. “Dissipative Self-Assembly: Fueling with Chemicals versus Light.” <i>Chem</i>. Elsevier, 2021. <a href=\"https://doi.org/10.1016/j.chempr.2020.11.025\">https://doi.org/10.1016/j.chempr.2020.11.025</a>.","short":"M. Weißenfels, J. Gemen, R. Klajn, Chem 7 (2021) 23–37.","mla":"Weißenfels, Maren, et al. “Dissipative Self-Assembly: Fueling with Chemicals versus Light.” <i>Chem</i>, vol. 7, no. 1, Elsevier, 2021, pp. 23–37, doi:<a href=\"https://doi.org/10.1016/j.chempr.2020.11.025\">10.1016/j.chempr.2020.11.025</a>.","ista":"Weißenfels M, Gemen J, Klajn R. 2021. Dissipative self-assembly: Fueling with chemicals versus light. Chem. 7(1), 23–37."},"year":"2021","date_updated":"2023-08-07T10:04:28Z","day":"14","doi":"10.1016/j.chempr.2020.11.025","abstract":[{"lang":"eng","text":"Dissipative self-assembly is ubiquitous in nature, where it gives rise to complex structures and functions such as self-healing, homeostasis, and camouflage. These phenomena are enabled by the continuous conversion of energy stored in chemical fuels, such as ATP. Over the past decade, an increasing number of synthetic chemically driven systems have been reported that mimic the features of their natural counterparts. At the same time, it has been shown that dissipative self-assembly can also be fueled by light; these optically fueled systems have been developed in parallel to the chemically fueled ones. In this perspective, we critically compare these two classes of systems. Despite the complementarity and fundamental differences between these two modes of dissipative self-assembly, our analysis reveals that multiple analogies exist between chemically and light-fueled systems. We hope that these considerations will facilitate further development of the field of dissipative self-assembly."}]},{"title":"All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields","intvolume":"        21","publication_status":"published","article_processing_charge":"No","date_created":"2023-08-09T13:09:15Z","author":[{"id":"71b4d059-2a03-11ee-914d-dfa3beed6530","last_name":"Baykusheva","first_name":"Denitsa Rangelova","full_name":"Baykusheva, Denitsa Rangelova"},{"last_name":"Chacón","first_name":"Alexis","full_name":"Chacón, Alexis"},{"full_name":"Lu, Jian","last_name":"Lu","first_name":"Jian"},{"first_name":"Trevor P.","last_name":"Bailey","full_name":"Bailey, Trevor P."},{"full_name":"Sobota, Jonathan A.","last_name":"Sobota","first_name":"Jonathan A."},{"full_name":"Soifer, Hadas","first_name":"Hadas","last_name":"Soifer"},{"first_name":"Patrick S.","last_name":"Kirchmann","full_name":"Kirchmann, Patrick S."},{"first_name":"Costel","last_name":"Rotundu","full_name":"Rotundu, Costel"},{"full_name":"Uher, Ctirad","first_name":"Ctirad","last_name":"Uher"},{"last_name":"Heinz","first_name":"Tony F.","full_name":"Heinz, Tony F."},{"full_name":"Reis, David A.","first_name":"David A.","last_name":"Reis"},{"last_name":"Ghimire","first_name":"Shambhu","full_name":"Ghimire, Shambhu"}],"issue":"21","pmid":1,"_id":"13996","scopus_import":"1","article_type":"original","publisher":"American Chemical Society","page":"8970-8978","quality_controlled":"1","abstract":[{"text":"We report the observation of an anomalous nonlinear optical response of the prototypical three-dimensional topological insulator bismuth selenide through the process of high-order harmonic generation. We find that the generation efficiency increases as the laser polarization is changed from linear to elliptical, and it becomes maximum for circular polarization. With the aid of a microscopic theory and a detailed analysis of the measured spectra, we reveal that such anomalous enhancement encodes the characteristic topology of the band structure that originates from the interplay of strong spin–orbit coupling and time-reversal symmetry protection. The implications are in ultrafast probing of topological phase transitions, light-field driven dissipationless electronics, and quantum computation.","lang":"eng"}],"doi":"10.1021/acs.nanolett.1c02145","arxiv":1,"day":"22","external_id":{"arxiv":["2109.15291"],"pmid":["34676752"]},"date_updated":"2023-08-22T07:32:00Z","citation":{"apa":"Baykusheva, D. R., Chacón, A., Lu, J., Bailey, T. P., Sobota, J. A., Soifer, H., … Ghimire, S. (2021). All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.1c02145\">https://doi.org/10.1021/acs.nanolett.1c02145</a>","ama":"Baykusheva DR, Chacón A, Lu J, et al. All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields. <i>Nano Letters</i>. 2021;21(21):8970-8978. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.1c02145\">10.1021/acs.nanolett.1c02145</a>","ieee":"D. R. Baykusheva <i>et al.</i>, “All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields,” <i>Nano Letters</i>, vol. 21, no. 21. American Chemical Society, pp. 8970–8978, 2021.","chicago":"Baykusheva, Denitsa Rangelova, Alexis Chacón, Jian Lu, Trevor P. Bailey, Jonathan A. Sobota, Hadas Soifer, Patrick S. Kirchmann, et al. “All-Optical Probe of Three-Dimensional Topological Insulators Based on High-Harmonic Generation by Circularly Polarized Laser Fields.” <i>Nano Letters</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/acs.nanolett.1c02145\">https://doi.org/10.1021/acs.nanolett.1c02145</a>.","short":"D.R. Baykusheva, A. Chacón, J. Lu, T.P. Bailey, J.A. Sobota, H. Soifer, P.S. Kirchmann, C. Rotundu, C. Uher, T.F. Heinz, D.A. Reis, S. Ghimire, Nano Letters 21 (2021) 8970–8978.","mla":"Baykusheva, Denitsa Rangelova, et al. “All-Optical Probe of Three-Dimensional Topological Insulators Based on High-Harmonic Generation by Circularly Polarized Laser Fields.” <i>Nano Letters</i>, vol. 21, no. 21, American Chemical Society, 2021, pp. 8970–78, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.1c02145\">10.1021/acs.nanolett.1c02145</a>.","ista":"Baykusheva DR, Chacón A, Lu J, Bailey TP, Sobota JA, Soifer H, Kirchmann PS, Rotundu C, Uher C, Heinz TF, Reis DA, Ghimire S. 2021. All-optical probe of three-dimensional topological insulators based on high-harmonic generation by circularly polarized laser fields. Nano Letters. 21(21), 8970–8978."},"year":"2021","extern":"1","volume":21,"month":"10","oa_version":"Published Version","publication":"Nano Letters","language":[{"iso":"eng"}],"keyword":["Mechanical Engineering","Condensed Matter Physics","General Materials Science","General Chemistry","Bioengineering"],"oa":1,"publication_identifier":{"eissn":["1530-6992"],"issn":["1530-6984"]},"date_published":"2021-10-22T00:00:00Z","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","main_file_link":[{"url":"https://doi.org/10.1021/acs.nanolett.1c02145","open_access":"1"}]},{"article_type":"original","publisher":"Springer Nature","file_date_updated":"2021-09-16T22:30:03Z","page":"465-471","quality_controlled":"1","title":"Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation","intvolume":"        13","publication_status":"published","article_processing_charge":"No","date_created":"2021-03-16T11:12:20Z","department":[{"_id":"StFr"}],"author":[{"full_name":"Petit, Yann K.","first_name":"Yann K.","last_name":"Petit"},{"full_name":"Mourad, Eléonore","last_name":"Mourad","first_name":"Eléonore"},{"full_name":"Prehal, Christian","last_name":"Prehal","first_name":"Christian"},{"last_name":"Leypold","first_name":"Christian","full_name":"Leypold, Christian"},{"first_name":"Andreas","last_name":"Windischbacher","full_name":"Windischbacher, Andreas"},{"full_name":"Mijailovic, Daniel","first_name":"Daniel","last_name":"Mijailovic"},{"full_name":"Slugovc, Christian","last_name":"Slugovc","first_name":"Christian"},{"last_name":"Borisov","first_name":"Sergey M.","full_name":"Borisov, Sergey M."},{"full_name":"Zojer, Egbert","first_name":"Egbert","last_name":"Zojer"},{"full_name":"Brutti, Sergio","first_name":"Sergio","last_name":"Brutti"},{"last_name":"Fontaine","first_name":"Olivier","full_name":"Fontaine, Olivier"},{"full_name":"Freunberger, Stefan Alexander","orcid":"0000-0003-2902-5319","last_name":"Freunberger","first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425"}],"issue":"5","pmid":1,"_id":"9250","scopus_import":"1","ddc":["540"],"volume":13,"acknowledgement":"S.A.F. is indebted to the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 636069) as well as IST Austria. O.F thanks the French National Research Agency (STORE-EX Labex Project ANR-10-LABX-76-01). We thank EL-Cell GmbH (Hamburg, Germany) for the pressure test cell. We thank R. Saf for help with the mass spectrometry, J. Schlegl for manufacturing instrumentation, M. Winkler of Acib GmbH, G. Strohmeier and R. Fürst for HPLC measurements and S. Mondal and S. Stadlbauer for kinetic measurements.","abstract":[{"lang":"eng","text":"Aprotic alkali metal–O2 batteries face two major obstacles to their chemistry occurring efficiently, the insulating nature of the formed alkali superoxides/peroxides and parasitic reactions that are caused by the highly reactive singlet oxygen (1O2). Redox mediators are recognized to be key for improving rechargeability. However, it is unclear how they affect 1O2 formation, which hinders strategies for their improvement. Here we clarify the mechanism of mediated peroxide and superoxide oxidation and thus explain how redox mediators either enhance or suppress 1O2 formation. We show that charging commences with peroxide oxidation to a superoxide intermediate and that redox potentials above ~3.5 V versus Li/Li+ drive 1O2 evolution from superoxide oxidation, while disproportionation always generates some 1O2. We find that 1O2 suppression requires oxidation to be faster than the generation of 1O2 from disproportionation. Oxidation rates decrease with growing driving force following Marcus inverted-region behaviour, establishing a region of maximum rate."}],"doi":"10.1038/s41557-021-00643-z","day":"15","isi":1,"external_id":{"isi":["000629296400001"],"pmid":["33723377"]},"date_updated":"2023-09-05T15:34:44Z","citation":{"ista":"Petit YK, Mourad E, Prehal C, Leypold C, Windischbacher A, Mijailovic D, Slugovc C, Borisov SM, Zojer E, Brutti S, Fontaine O, Freunberger SA. 2021. Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. Nature Chemistry. 13(5), 465–471.","mla":"Petit, Yann K., et al. “Mechanism of Mediated Alkali Peroxide Oxidation and Triplet versus Singlet Oxygen Formation.” <i>Nature Chemistry</i>, vol. 13, no. 5, Springer Nature, 2021, pp. 465–71, doi:<a href=\"https://doi.org/10.1038/s41557-021-00643-z\">10.1038/s41557-021-00643-z</a>.","short":"Y.K. Petit, E. Mourad, C. Prehal, C. Leypold, A. Windischbacher, D. Mijailovic, C. Slugovc, S.M. Borisov, E. Zojer, S. Brutti, O. Fontaine, S.A. Freunberger, Nature Chemistry 13 (2021) 465–471.","chicago":"Petit, Yann K., Eléonore Mourad, Christian Prehal, Christian Leypold, Andreas Windischbacher, Daniel Mijailovic, Christian Slugovc, et al. “Mechanism of Mediated Alkali Peroxide Oxidation and Triplet versus Singlet Oxygen Formation.” <i>Nature Chemistry</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41557-021-00643-z\">https://doi.org/10.1038/s41557-021-00643-z</a>.","ieee":"Y. K. Petit <i>et al.</i>, “Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation,” <i>Nature Chemistry</i>, vol. 13, no. 5. Springer Nature, pp. 465–471, 2021.","apa":"Petit, Y. K., Mourad, E., Prehal, C., Leypold, C., Windischbacher, A., Mijailovic, D., … Freunberger, S. A. (2021). Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. <i>Nature Chemistry</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41557-021-00643-z\">https://doi.org/10.1038/s41557-021-00643-z</a>","ama":"Petit YK, Mourad E, Prehal C, et al. Mechanism of mediated alkali peroxide oxidation and triplet versus singlet oxygen formation. <i>Nature Chemistry</i>. 2021;13(5):465-471. doi:<a href=\"https://doi.org/10.1038/s41557-021-00643-z\">10.1038/s41557-021-00643-z</a>"},"year":"2021","language":[{"iso":"eng"}],"keyword":["General Chemistry","General Chemical Engineering"],"month":"03","acknowledged_ssus":[{"_id":"M-Shop"}],"oa_version":"Submitted Version","publication":"Nature Chemistry","has_accepted_license":"1","status":"public","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","file":[{"file_name":"2021_NatureChem_Petit_acceptedVersion.pdf","content_type":"application/pdf","date_updated":"2021-09-16T22:30:03Z","checksum":"3ee3f8dd79ed1b7bb0929fce184c8012","file_size":1811448,"embargo":"2021-09-15","date_created":"2021-03-22T11:46:00Z","creator":"dernst","file_id":"9276","access_level":"open_access","relation":"main_file"}],"oa":1,"publication_identifier":{"issn":["1755-4330"],"eissn":["1755-4349"]},"date_published":"2021-03-15T00:00:00Z","type":"journal_article"},{"type":"journal_article","date_published":"2021-04-06T00:00:00Z","oa":1,"publication_identifier":{"issn":["2053-1583"]},"status":"public","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","main_file_link":[{"url":"https://arxiv.org/abs/2103.09029","open_access":"1"}],"publication":"2D Materials","article_number":"035011","month":"04","oa_version":"Preprint","keyword":["Mechanical Engineering","General Materials Science","Mechanics of Materials","General Chemistry","Condensed Matter Physics"],"language":[{"iso":"eng"}],"external_id":{"arxiv":["2103.09029"]},"year":"2021","citation":{"apa":"Nauman, M., Kiem, D. H., Lee, S., Son, S., Park, J.-G., Kang, W., … Jo, Y. J. (2021). Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. <i>2D Materials</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/2053-1583/abeed3\">https://doi.org/10.1088/2053-1583/abeed3</a>","ama":"Nauman M, Kiem DH, Lee S, et al. Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. <i>2D Materials</i>. 2021;8(3). doi:<a href=\"https://doi.org/10.1088/2053-1583/abeed3\">10.1088/2053-1583/abeed3</a>","chicago":"Nauman, Muhammad, Do Hoon Kiem, Sungmin Lee, Suhan Son, J-G Park, Woun Kang, Myung Joon Han, and Youn Jung Jo. “Complete Mapping of Magnetic Anisotropy for Prototype Ising van Der Waals FePS3.” <i>2D Materials</i>. IOP Publishing, 2021. <a href=\"https://doi.org/10.1088/2053-1583/abeed3\">https://doi.org/10.1088/2053-1583/abeed3</a>.","ieee":"M. Nauman <i>et al.</i>, “Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3,” <i>2D Materials</i>, vol. 8, no. 3. IOP Publishing, 2021.","short":"M. Nauman, D.H. Kiem, S. Lee, S. Son, J.-G. Park, W. Kang, M.J. Han, Y.J. Jo, 2D Materials 8 (2021).","mla":"Nauman, Muhammad, et al. “Complete Mapping of Magnetic Anisotropy for Prototype Ising van Der Waals FePS3.” <i>2D Materials</i>, vol. 8, no. 3, 035011, IOP Publishing, 2021, doi:<a href=\"https://doi.org/10.1088/2053-1583/abeed3\">10.1088/2053-1583/abeed3</a>.","ista":"Nauman M, Kiem DH, Lee S, Son S, Park J-G, Kang W, Han MJ, Jo YJ. 2021. Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. 2D Materials. 8(3), 035011."},"date_updated":"2021-12-01T10:36:56Z","abstract":[{"text":"Several Ising-type magnetic van der Waals (vdW) materials exhibit stable magnetic ground states. Despite these clear experimental demonstrations, a complete theoretical and microscopic understanding of their magnetic anisotropy is still lacking. In particular, the validity limit of identifying their one-dimensional (1-D) Ising nature has remained uninvestigated in a quantitative way. Here we performed the complete mapping of magnetic anisotropy for a prototypical Ising vdW magnet FePS3 for the first time. Combining torque magnetometry measurements with their magnetostatic model analysis and the relativistic density functional total energy calculations, we successfully constructed the three-dimensional (3-D) mappings of the magnetic anisotropy in terms of magnetic torque and energy. The results not only quantitatively confirm that the easy axis is perpendicular to the ab plane, but also reveal the anisotropies within the ab, ac, and bc planes. Our approach can be applied to the detailed quantitative study of magnetism in vdW materials.","lang":"eng"}],"day":"06","doi":"10.1088/2053-1583/abeed3","arxiv":1,"extern":"1","volume":8,"issue":"3","author":[{"last_name":"Nauman","first_name":"Muhammad","full_name":"Nauman, Muhammad","orcid":"0000-0002-2111-4846","id":"32c21954-2022-11eb-9d5f-af9f93c24e71"},{"full_name":"Kiem, Do Hoon","last_name":"Kiem","first_name":"Do Hoon"},{"first_name":"Sungmin","last_name":"Lee","full_name":"Lee, Sungmin"},{"last_name":"Son","first_name":"Suhan","full_name":"Son, Suhan"},{"last_name":"Park","first_name":"J-G","full_name":"Park, J-G"},{"full_name":"Kang, Woun","first_name":"Woun","last_name":"Kang"},{"first_name":"Myung Joon","last_name":"Han","full_name":"Han, Myung Joon"},{"full_name":"Jo, Youn Jung","first_name":"Youn Jung","last_name":"Jo"}],"_id":"9282","intvolume":"         8","title":"Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3","date_created":"2021-03-23T07:10:17Z","article_processing_charge":"No","department":[{"_id":"KiMo"}],"publication_status":"published","quality_controlled":"1","article_type":"original","publisher":"IOP Publishing"},{"acknowledgement":"This work was funded by the National Institute of Allergy and Infectious Diseases under awards R01AI147890 to R.A.D., R01AI150454 to V.M.V, R35GM136258 in support of J-P.R.F, and the Austrian Science Fund (FWF) grant P31445 to F.K.M.S. Access to high-resolution cryo-ET data acquisition at EMBL Heidelberg was supported by iNEXT (grant no. 653706), funded by the Horizon 2020 program of the European Union (PID 4246). We thank Wim Hagen and Felix Weis at EMBL Heidelberg for support in cryo-ET data acquisition. This work made use of the Cornell Center for Materials Research Shared Facilities, which are supported through the NSF MRSEC program (DMR-179875). This research was also supported by the Scientific Service Units (SSUs) of IST Austria through resources provided by Scientific Computing (SciComp), the Life Science Facility (LSF), and the Electron Microscopy Facility (EMF).","volume":12,"ddc":["570"],"year":"2021","citation":{"apa":"Obr, M., Ricana, C. L., Nikulin, N., Feathers, J.-P. R., Klanschnig, M., Thader, A., … Dick, R. A. (2021). Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. <i>Nature Communications</i>. Nature Research. <a href=\"https://doi.org/10.1038/s41467-021-23506-0\">https://doi.org/10.1038/s41467-021-23506-0</a>","ama":"Obr M, Ricana CL, Nikulin N, et al. Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-23506-0\">10.1038/s41467-021-23506-0</a>","ieee":"M. Obr <i>et al.</i>, “Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer,” <i>Nature Communications</i>, vol. 12, no. 1. Nature Research, 2021.","chicago":"Obr, Martin, Clifton L. Ricana, Nadia Nikulin, Jon-Philip R. Feathers, Marco Klanschnig, Andreas Thader, Marc C. Johnson, Volker M. Vogt, Florian KM Schur, and Robert A. Dick. “Structure of the Mature Rous Sarcoma Virus Lattice Reveals a Role for IP6 in the Formation of the Capsid Hexamer.” <i>Nature Communications</i>. Nature Research, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23506-0\">https://doi.org/10.1038/s41467-021-23506-0</a>.","mla":"Obr, Martin, et al. “Structure of the Mature Rous Sarcoma Virus Lattice Reveals a Role for IP6 in the Formation of the Capsid Hexamer.” <i>Nature Communications</i>, vol. 12, no. 1, 3226, Nature Research, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23506-0\">10.1038/s41467-021-23506-0</a>.","short":"M. Obr, C.L. Ricana, N. Nikulin, J.-P.R. Feathers, M. Klanschnig, A. Thader, M.C. Johnson, V.M. Vogt, F.K. Schur, R.A. Dick, Nature Communications 12 (2021).","ista":"Obr M, Ricana CL, Nikulin N, Feathers J-PR, Klanschnig M, Thader A, Johnson MC, Vogt VM, Schur FK, Dick RA. 2021. Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nature Communications. 12(1), 3226."},"date_updated":"2023-08-08T13:53:53Z","external_id":{"isi":["000659145000011"]},"isi":1,"day":"28","doi":"10.1038/s41467-021-23506-0","abstract":[{"lang":"eng","text":"Inositol hexakisphosphate (IP6) is an assembly cofactor for HIV-1. We report here that IP6 is also used for assembly of Rous sarcoma virus (RSV), a retrovirus from a different genus. IP6 is ~100-fold more potent at promoting RSV mature capsid protein (CA) assembly than observed for HIV-1 and removal of IP6 in cells reduces infectivity by 100-fold. Here, visualized by cryo-electron tomography and subtomogram averaging, mature capsid-like particles show an IP6-like density in the CA hexamer, coordinated by rings of six lysines and six arginines. Phosphate and IP6 have opposing effects on CA in vitro assembly, inducing formation of T = 1 icosahedrons and tubes, respectively, implying that phosphate promotes pentamer and IP6 hexamer formation. Subtomogram averaging and classification optimized for analysis of pleomorphic retrovirus particles reveal that the heterogeneity of mature RSV CA polyhedrons results from an unexpected, intrinsic CA hexamer flexibility. In contrast, the CA pentamer forms rigid units organizing the local architecture. These different features of hexamers and pentamers determine the structural mechanism to form CA polyhedrons of variable shape in mature RSV particles."}],"quality_controlled":"1","file_date_updated":"2021-06-09T15:21:14Z","publisher":"Nature Research","article_type":"original","scopus_import":"1","_id":"9431","issue":"1","author":[{"id":"4741CA5A-F248-11E8-B48F-1D18A9856A87","first_name":"Martin","last_name":"Obr","full_name":"Obr, Martin"},{"last_name":"Ricana","first_name":"Clifton L.","full_name":"Ricana, Clifton L."},{"full_name":"Nikulin, Nadia","last_name":"Nikulin","first_name":"Nadia"},{"last_name":"Feathers","first_name":"Jon-Philip R.","full_name":"Feathers, Jon-Philip R."},{"full_name":"Klanschnig, Marco","last_name":"Klanschnig","first_name":"Marco"},{"id":"3A18A7B8-F248-11E8-B48F-1D18A9856A87","last_name":"Thader","first_name":"Andreas","full_name":"Thader, Andreas"},{"full_name":"Johnson, Marc C.","first_name":"Marc C.","last_name":"Johnson"},{"full_name":"Vogt, Volker M.","first_name":"Volker M.","last_name":"Vogt"},{"orcid":"0000-0003-4790-8078","full_name":"Schur, Florian KM","first_name":"Florian KM","last_name":"Schur","id":"48AD8942-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Dick, Robert A.","last_name":"Dick","first_name":"Robert A."}],"date_created":"2021-05-28T14:25:50Z","department":[{"_id":"FlSc"}],"article_processing_charge":"No","publication_status":"published","intvolume":"        12","title":"Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer","file":[{"success":1,"access_level":"open_access","relation":"main_file","creator":"kschuh","file_id":"9538","file_size":6166295,"checksum":"53ccc53d09a9111143839dbe7784e663","date_created":"2021-06-09T15:21:14Z","content_type":"application/pdf","file_name":"2021_NatureCommunications_Obr.pdf","date_updated":"2021-06-09T15:21:14Z"}],"status":"public","related_material":{"link":[{"description":"News on IST Homepage","relation":"press_release","url":"https://ist.ac.at/en/news/how-retroviruses-become-infectious/"}]},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"journal_article","date_published":"2021-05-28T00:00:00Z","publication_identifier":{"eissn":["2041-1723"]},"oa":1,"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"language":[{"iso":"eng"}],"has_accepted_license":"1","publication":"Nature Communications","project":[{"grant_number":"P31445","name":"Structural conservation and diversity in retroviral capsid","_id":"26736D6A-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"EM-Fac"}],"oa_version":"Published Version","article_number":"3226","month":"05"},{"type":"journal_article","date_published":"2021-06-09T00:00:00Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"publication_identifier":{"eissn":["2041-1723"]},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","file":[{"checksum":"40fc24c1310930990b52a8ad1142ee97","file_size":3397292,"date_created":"2021-06-15T18:55:59Z","file_name":"2021_NatureComm_Prattes.pdf","content_type":"application/pdf","date_updated":"2021-06-15T18:55:59Z","access_level":"open_access","relation":"main_file","success":1,"creator":"cziletti","file_id":"9556"}],"has_accepted_license":"1","publication":"Nature Communications","article_number":"3483","month":"06","oa_version":"Published Version","acknowledged_ssus":[{"_id":"EM-Fac"}],"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"language":[{"iso":"eng"}],"external_id":{"isi":["000664874700014"],"pmid":["34108481"]},"isi":1,"citation":{"ista":"Prattes M, Grishkovskaya I, Hodirnau V-V, Rössler I, Klein I, Hetzmannseder C, Zisser G, Gruber CC, Gruber K, Haselbach D, Bergler H. 2021. Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. Nature Communications. 12(1), 3483.","short":"M. Prattes, I. Grishkovskaya, V.-V. Hodirnau, I. Rössler, I. Klein, C. Hetzmannseder, G. Zisser, C.C. Gruber, K. Gruber, D. Haselbach, H. Bergler, Nature Communications 12 (2021).","mla":"Prattes, Michael, et al. “Structural Basis for Inhibition of the AAA-ATPase Drg1 by Diazaborine.” <i>Nature Communications</i>, vol. 12, no. 1, 3483, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23854-x\">10.1038/s41467-021-23854-x</a>.","chicago":"Prattes, Michael, Irina Grishkovskaya, Victor-Valentin Hodirnau, Ingrid Rössler, Isabella Klein, Christina Hetzmannseder, Gertrude Zisser, et al. “Structural Basis for Inhibition of the AAA-ATPase Drg1 by Diazaborine.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23854-x\">https://doi.org/10.1038/s41467-021-23854-x</a>.","ieee":"M. Prattes <i>et al.</i>, “Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine,” <i>Nature Communications</i>, vol. 12, no. 1. Springer Nature, 2021.","ama":"Prattes M, Grishkovskaya I, Hodirnau V-V, et al. Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-23854-x\">10.1038/s41467-021-23854-x</a>","apa":"Prattes, M., Grishkovskaya, I., Hodirnau, V.-V., Rössler, I., Klein, I., Hetzmannseder, C., … Bergler, H. (2021). Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-23854-x\">https://doi.org/10.1038/s41467-021-23854-x</a>"},"year":"2021","date_updated":"2023-08-08T14:05:26Z","abstract":[{"text":"The hexameric AAA-ATPase Drg1 is a key factor in eukaryotic ribosome biogenesis and initiates cytoplasmic maturation of the large ribosomal subunit by releasing the shuttling maturation factor Rlp24. Drg1 monomers contain two AAA-domains (D1 and D2) that act in a concerted manner. Rlp24 release is inhibited by the drug diazaborine which blocks ATP hydrolysis in D2. The mode of inhibition was unknown. Here we show the first cryo-EM structure of Drg1 revealing the inhibitory mechanism. Diazaborine forms a covalent bond to the 2′-OH of the nucleotide in D2, explaining its specificity for this site. As a consequence, the D2 domain is locked in a rigid, inactive state, stalling the whole Drg1 hexamer. Resistance mechanisms identified include abolished drug binding and altered positioning of the nucleotide. Our results suggest nucleotide-modifying compounds as potential novel inhibitors for AAA-ATPases.","lang":"eng"}],"day":"09","doi":"10.1038/s41467-021-23854-x","ddc":["570"],"volume":12,"acknowledgement":"We are deeply grateful to the late Gregor Högenauer who built the foundation for this study with his visionary work on the inhibitor diazaborine and its bacterial target. We thank Rolf Breinbauer for insightful discussions on boron chemistry. We thank Anton Meinhart and Tim Clausen for the valuable discussion of the manuscript. We are indebted to Thomas Köcher for the MS measurement of the diazaborine-ATPγS adduct. We thank the team of the VBCF for support during early phases of this work and the IST Austria Electron Microscopy Facility for providing equipment. The lab of D.H. is supported by Boehringer Ingelheim. The work was funded by FWF projects P32536 and P32977 (to H.B.).","issue":"1","author":[{"full_name":"Prattes, Michael","last_name":"Prattes","first_name":"Michael"},{"first_name":"Irina","last_name":"Grishkovskaya","full_name":"Grishkovskaya, Irina"},{"full_name":"Hodirnau, Victor-Valentin","last_name":"Hodirnau","first_name":"Victor-Valentin","id":"3661B498-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Rössler, Ingrid","last_name":"Rössler","first_name":"Ingrid"},{"last_name":"Klein","first_name":"Isabella","full_name":"Klein, Isabella"},{"last_name":"Hetzmannseder","first_name":"Christina","full_name":"Hetzmannseder, Christina"},{"full_name":"Zisser, Gertrude","last_name":"Zisser","first_name":"Gertrude"},{"last_name":"Gruber","first_name":"Christian C.","full_name":"Gruber, Christian C."},{"first_name":"Karl","last_name":"Gruber","full_name":"Gruber, Karl"},{"first_name":"David","last_name":"Haselbach","full_name":"Haselbach, David"},{"full_name":"Bergler, Helmut","first_name":"Helmut","last_name":"Bergler"}],"pmid":1,"_id":"9540","intvolume":"        12","title":"Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine","department":[{"_id":"EM-Fac"}],"date_created":"2021-06-10T14:57:45Z","article_processing_charge":"No","publication_status":"published","file_date_updated":"2021-06-15T18:55:59Z","quality_controlled":"1","article_type":"original","publisher":"Springer Nature"},{"publisher":"Springer Nature","article_type":"original","quality_controlled":"1","file_date_updated":"2021-10-21T13:51:49Z","publication_status":"published","department":[{"_id":"CaBe"}],"date_created":"2021-10-20T14:40:32Z","article_processing_charge":"No","title":"PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC","intvolume":"        12","_id":"10163","author":[{"full_name":"Appel, Lisa-Marie","first_name":"Lisa-Marie","last_name":"Appel"},{"full_name":"Franke, Vedran","first_name":"Vedran","last_name":"Franke"},{"full_name":"Bruno, Melania","last_name":"Bruno","first_name":"Melania"},{"first_name":"Irina","last_name":"Grishkovskaya","full_name":"Grishkovskaya, Irina"},{"last_name":"Kasiliauskaite","first_name":"Aiste","full_name":"Kasiliauskaite, Aiste"},{"last_name":"Kaufmann","first_name":"Tanja","full_name":"Kaufmann, Tanja"},{"full_name":"Schoeberl, Ursula E.","last_name":"Schoeberl","first_name":"Ursula E."},{"full_name":"Puchinger, Martin G.","first_name":"Martin G.","last_name":"Puchinger"},{"last_name":"Kostrhon","first_name":"Sebastian","full_name":"Kostrhon, Sebastian"},{"last_name":"Ebenwaldner","first_name":"Carmen","full_name":"Ebenwaldner, Carmen"},{"first_name":"Marek","last_name":"Sebesta","full_name":"Sebesta, Marek"},{"full_name":"Beltzung, Etienne","first_name":"Etienne","last_name":"Beltzung"},{"full_name":"Mechtler, Karl","last_name":"Mechtler","first_name":"Karl"},{"last_name":"Lin","first_name":"Gen","full_name":"Lin, Gen"},{"full_name":"Vlasova, Anna","last_name":"Vlasova","first_name":"Anna"},{"first_name":"Martin","last_name":"Leeb","full_name":"Leeb, Martin"},{"first_name":"Rushad","last_name":"Pavri","full_name":"Pavri, Rushad"},{"full_name":"Stark, Alexander","last_name":"Stark","first_name":"Alexander"},{"first_name":"Altuna","last_name":"Akalin","full_name":"Akalin, Altuna"},{"last_name":"Stefl","first_name":"Richard","full_name":"Stefl, Richard"},{"id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87","full_name":"Bernecky, Carrie A","orcid":"0000-0003-0893-7036","last_name":"Bernecky","first_name":"Carrie A"},{"full_name":"Djinovic-Carugo, Kristina","last_name":"Djinovic-Carugo","first_name":"Kristina"},{"first_name":"Dea","last_name":"Slade","full_name":"Slade, Dea"}],"issue":"1","acknowledgement":"D.S. thanks Claudine Kraft, Renée Schroeder, Verena Jantsch, Franz Klein and Peter Schlögelhofer for support. We thank Anita Testa Salmazo for help with purifying Pol II; Matthias Geyer and Robert Düster for sharing DYRK1A kinase; Felix Hartmann and Clemens Plaschka for help with mass photometry; Goran Kokic for design of the arrest assay sequences; Petra van der Lelij for help with generating mESC KO; Maximilian Freilinger for help with the purification of mEGFP-CTD; Stefan Ameres, Nina Fasching and Brian Reichholf for advice on SLAM-seq and for sharing reagents; Laura Gallego Valle for advice regarding LLPS assays; Krzysztof Chylinski for advice regarding CRISPR/Cas9 methodology; VBCF Protein Technologies facility for purifying PHF3 and providing gRNAs and Cas9; VBCF NGS facility for sequencing; Monoclonal antibody facility at the Helmholtz center for Pol II antibodies; Friedrich Propst and Elzbieta Kowalska for advice and for sharing materials; Egon Ogris for sharing materials; Martin Eilers for recommending a ChIP-grade TFIIS antibody; Susanne Opravil, Otto Hudecz, Markus Hartl and Natascha Hartl for mass spectrometry analysis; staff of the X-ray beamlines at the ESRF in Grenoble for their excellent support; Christa Bücker, Anton Meinhart, Clemens Plaschka and members of the Slade lab for critical comments on the manuscript; Life Science Editors for editing assistance. M.B. and D.S. acknowledge support by the FWF-funded DK ‘Chromosome Dynamics’. T.K. is a recipient of the DOC fellowship from the Austrian Academy of Sciences. U.S. is supported by the L’Oreal for Women in Science Austria Fellowship and the Austrian Science Fund (FWF T 795-B30). M.L is supported by the Vienna Science and Technology Fund (WWTF, VRG14-006). R.S. is supported by the Czech Science Foundation (15-17670 S and 21-24460 S), Ministry of Education, Youths and Sports of the Czech Republic (CEITEC 2020 project (LQ1601)), and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement no. 649030); this publication reflects only the author’s view and the Research Executive Agency is not responsible for any use that may be made of the information it contains. M.S. is supported by the Czech Science Foundation (GJ20-21581Y). K.D.C. research is supported by the Austrian Science Fund (FWF) Projects I525 and I1593, P22276, P19060, and W1221, Federal Ministry of Economy, Family and Youth through the initiative ‘Laura Bassi Centres of Expertise’, funding from the Centre of Optimized Structural Studies No. 253275, the Wellcome Trust Collaborative Award (201543/Z/16), COST action BM1405 Non-globular proteins - from sequence to structure, function and application in molecular physiopathology (NGP-NET), the Vienna Science and Technology Fund (WWTF LS17-008), and by the University of Vienna. This project was funded by the MFPL start-up grant, the Vienna Science and Technology Fund (WWTF LS14-001), and the Austrian Science Fund (P31546-B28 and W1258 “DK: Integrative Structural Biology”) to D.S.","volume":12,"ddc":["610"],"doi":"10.1038/s41467-021-26360-2","day":"19","abstract":[{"text":"The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is a regulatory hub for transcription and RNA processing. Here, we identify PHD-finger protein 3 (PHF3) as a regulator of transcription and mRNA stability that docks onto Pol II CTD through its SPOC domain. We characterize SPOC as a CTD reader domain that preferentially binds two phosphorylated Serine-2 marks in adjacent CTD repeats. PHF3 drives liquid-liquid phase separation of phosphorylated Pol II, colocalizes with Pol II clusters and tracks with Pol II across the length of genes. PHF3 knock-out or SPOC deletion in human cells results in increased Pol II stalling, reduced elongation rate and an increase in mRNA stability, with marked derepression of neuronal genes. Key neuronal genes are aberrantly expressed in Phf3 knock-out mouse embryonic stem cells, resulting in impaired neuronal differentiation. Our data suggest that PHF3 acts as a prominent effector of neuronal gene regulation by bridging transcription with mRNA decay.","lang":"eng"}],"date_updated":"2023-08-14T08:02:31Z","citation":{"ista":"Appel L-M, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. 2021. PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. Nature Communications. 12(1), 6078.","mla":"Appel, Lisa-Marie, et al. “PHF3 Regulates Neuronal Gene Expression through the Pol II CTD Reader Domain SPOC.” <i>Nature Communications</i>, vol. 12, no. 1, 6078, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-26360-2\">10.1038/s41467-021-26360-2</a>.","short":"L.-M. Appel, V. Franke, M. Bruno, I. Grishkovskaya, A. Kasiliauskaite, T. Kaufmann, U.E. Schoeberl, M.G. Puchinger, S. Kostrhon, C. Ebenwaldner, M. Sebesta, E. Beltzung, K. Mechtler, G. Lin, A. Vlasova, M. Leeb, R. Pavri, A. Stark, A. Akalin, R. Stefl, C. Bernecky, K. Djinovic-Carugo, D. Slade, Nature Communications 12 (2021).","chicago":"Appel, Lisa-Marie, Vedran Franke, Melania Bruno, Irina Grishkovskaya, Aiste Kasiliauskaite, Tanja Kaufmann, Ursula E. Schoeberl, et al. “PHF3 Regulates Neuronal Gene Expression through the Pol II CTD Reader Domain SPOC.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-26360-2\">https://doi.org/10.1038/s41467-021-26360-2</a>.","ieee":"L.-M. Appel <i>et al.</i>, “PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC,” <i>Nature Communications</i>, vol. 12, no. 1. Springer Nature, 2021.","apa":"Appel, L.-M., Franke, V., Bruno, M., Grishkovskaya, I., Kasiliauskaite, A., Kaufmann, T., … Slade, D. (2021). PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-26360-2\">https://doi.org/10.1038/s41467-021-26360-2</a>","ama":"Appel L-M, Franke V, Bruno M, et al. PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-26360-2\">10.1038/s41467-021-26360-2</a>"},"year":"2021","isi":1,"external_id":{"isi":["000709050300001"]},"language":[{"iso":"eng"}],"keyword":["general physics and astronomy","general biochemistry","genetics and molecular biology","general chemistry"],"oa_version":"Published Version","month":"10","article_number":"6078","publication":"Nature Communications","has_accepted_license":"1","file":[{"content_type":"application/pdf","file_name":"2021_NatComm_Appel.pdf","date_updated":"2021-10-21T13:51:49Z","checksum":"d99fcd51aebde19c21314e3de0148007","file_size":5111706,"date_created":"2021-10-21T13:51:49Z","creator":"cchlebak","file_id":"10169","success":1,"access_level":"open_access","relation":"main_file"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","related_material":{"link":[{"description":"Preprint ","relation":"earlier_version","url":"https://www.biorxiv.org/content/10.1101/2020.02.11.943159"}]},"publication_identifier":{"eissn":["2041-1723"]},"oa":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_published":"2021-10-19T00:00:00Z","type":"journal_article"},{"extern":"1","volume":17,"acknowledgement":"We acknowledge support from the Royal Society (C. V. C. and A. Sˇ.), the Medical Research Council (C. V. C. and A. Sˇ.), and the European Research Council (Starting grant ‘‘NEPA’’ 802960 to A. Sˇ.). We thank Johannes Krausser and Ivan Palaia for fruitful discussions.","external_id":{"pmid":["33629089"]},"date_updated":"2021-11-30T08:20:09Z","citation":{"ama":"Vanhille-Campos C, Šarić A. Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. <i>Soft Matter</i>. 2021;17(14):3798-3806. doi:<a href=\"https://doi.org/10.1039/d0sm02012e\">10.1039/d0sm02012e</a>","apa":"Vanhille-Campos, C., &#38; Šarić, A. (2021). Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. <i>Soft Matter</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d0sm02012e\">https://doi.org/10.1039/d0sm02012e</a>","chicago":"Vanhille-Campos, Christian, and Anđela Šarić. “Modelling the Dynamics of Vesicle Reshaping and Scission under Osmotic Shocks.” <i>Soft Matter</i>. Royal Society of Chemistry, 2021. <a href=\"https://doi.org/10.1039/d0sm02012e\">https://doi.org/10.1039/d0sm02012e</a>.","ieee":"C. Vanhille-Campos and A. Šarić, “Modelling the dynamics of vesicle reshaping and scission under osmotic shocks,” <i>Soft Matter</i>, vol. 17, no. 14. Royal Society of Chemistry, pp. 3798–3806, 2021.","mla":"Vanhille-Campos, Christian, and Anđela Šarić. “Modelling the Dynamics of Vesicle Reshaping and Scission under Osmotic Shocks.” <i>Soft Matter</i>, vol. 17, no. 14, Royal Society of Chemistry, 2021, pp. 3798–806, doi:<a href=\"https://doi.org/10.1039/d0sm02012e\">10.1039/d0sm02012e</a>.","short":"C. Vanhille-Campos, A. Šarić, Soft Matter 17 (2021) 3798–3806.","ista":"Vanhille-Campos C, Šarić A. 2021. Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. Soft Matter. 17(14), 3798–3806."},"year":"2021","abstract":[{"lang":"eng","text":"We study the effects of osmotic shocks on lipid vesicles via coarse-grained molecular dynamics simulations by explicitly considering the solute in the system. We find that depending on their nature (hypo- or hypertonic) such shocks can lead to bursting events or engulfing of external material into inner compartments, among other morphology transformations. We characterize the dynamics of these processes and observe a separation of time scales between the osmotic shock absorption and the shape relaxation. Our work consequently provides an insight into the dynamics of compartmentalization in vesicular systems as a result of osmotic shocks, which can be of interest in the context of early proto-cell development and proto-cell compartmentalisation."}],"doi":"10.1039/d0sm02012e","day":"16","page":"3798-3806","quality_controlled":"1","article_type":"original","publisher":"Royal Society of Chemistry","author":[{"full_name":"Vanhille-Campos, Christian","last_name":"Vanhille-Campos","first_name":"Christian"},{"last_name":"Šarić","first_name":"Anđela","full_name":"Šarić, Anđela","orcid":"0000-0002-7854-2139","id":"bf63d406-f056-11eb-b41d-f263a6566d8b"}],"issue":"14","pmid":1,"_id":"10339","license":"https://creativecommons.org/licenses/by-nc/3.0/","scopus_import":"1","title":"Modelling the dynamics of vesicle reshaping and scission under osmotic shocks","intvolume":"        17","publication_status":"published","article_processing_charge":"No","date_created":"2021-11-25T16:06:42Z","status":"public","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","related_material":{"link":[{"url":"https://www.biorxiv.org/content/10.1101/2020.11.16.384602v2","relation":"earlier_version"}]},"main_file_link":[{"open_access":"1","url":"https://pubs.rsc.org/en/content/articlehtml/2021/sm/d0sm02012e"}],"date_published":"2021-02-16T00:00:00Z","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/3.0/legalcode","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)","short":"CC BY-NC (3.0)"},"oa":1,"publication_identifier":{"issn":["1744-683X"],"eissn":["1744-6848"]},"language":[{"iso":"eng"}],"keyword":["condensed matter physics","general chemistry"],"publication":"Soft Matter","month":"02","oa_version":"Published Version"},{"publication":"Nature Communications","oa_version":"Published Version","article_number":"2868","month":"05","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"language":[{"iso":"eng"}],"type":"journal_article","date_published":"2021-05-17T00:00:00Z","publication_identifier":{"issn":["2041-1723"]},"oa":1,"main_file_link":[{"url":"https://doi.org/10.1038/s41467-021-23073-4","open_access":"1"}],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","_id":"12585","author":[{"first_name":"Evan","last_name":"Miles","full_name":"Miles, Evan"},{"last_name":"McCarthy","first_name":"Michael","full_name":"McCarthy, Michael"},{"full_name":"Dehecq, Amaury","last_name":"Dehecq","first_name":"Amaury"},{"first_name":"Marin","last_name":"Kneib","full_name":"Kneib, Marin"},{"full_name":"Fugger, Stefan","first_name":"Stefan","last_name":"Fugger"},{"id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","first_name":"Francesca"}],"article_processing_charge":"No","date_created":"2023-02-20T08:11:29Z","publication_status":"published","intvolume":"        12","title":"Health and sustainability of glaciers in High Mountain Asia","quality_controlled":"1","publisher":"Springer Nature","article_type":"original","year":"2021","citation":{"ieee":"E. Miles, M. McCarthy, A. Dehecq, M. Kneib, S. Fugger, and F. Pellicciotti, “Health and sustainability of glaciers in High Mountain Asia,” <i>Nature Communications</i>, vol. 12. Springer Nature, 2021.","chicago":"Miles, Evan, Michael McCarthy, Amaury Dehecq, Marin Kneib, Stefan Fugger, and Francesca Pellicciotti. “Health and Sustainability of Glaciers in High Mountain Asia.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23073-4\">https://doi.org/10.1038/s41467-021-23073-4</a>.","apa":"Miles, E., McCarthy, M., Dehecq, A., Kneib, M., Fugger, S., &#38; Pellicciotti, F. (2021). Health and sustainability of glaciers in High Mountain Asia. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-23073-4\">https://doi.org/10.1038/s41467-021-23073-4</a>","ama":"Miles E, McCarthy M, Dehecq A, Kneib M, Fugger S, Pellicciotti F. Health and sustainability of glaciers in High Mountain Asia. <i>Nature Communications</i>. 2021;12. doi:<a href=\"https://doi.org/10.1038/s41467-021-23073-4\">10.1038/s41467-021-23073-4</a>","ista":"Miles E, McCarthy M, Dehecq A, Kneib M, Fugger S, Pellicciotti F. 2021. Health and sustainability of glaciers in High Mountain Asia. Nature Communications. 12, 2868.","mla":"Miles, Evan, et al. “Health and Sustainability of Glaciers in High Mountain Asia.” <i>Nature Communications</i>, vol. 12, 2868, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23073-4\">10.1038/s41467-021-23073-4</a>.","short":"E. Miles, M. McCarthy, A. Dehecq, M. Kneib, S. Fugger, F. Pellicciotti, Nature Communications 12 (2021)."},"date_updated":"2023-02-28T13:21:51Z","day":"17","doi":"10.1038/s41467-021-23073-4","abstract":[{"text":"Glaciers in High Mountain Asia generate meltwater that supports the water needs of 250 million people, but current knowledge of annual accumulation and ablation is limited to sparse field measurements biased in location and glacier size. Here, we present altitudinally-resolved specific mass balances (surface, internal, and basal combined) for 5527 glaciers in High Mountain Asia for 2000–2016, derived by correcting observed glacier thinning patterns for mass redistribution due to ice flow. We find that 41% of glaciers accumulated mass over less than 20% of their area, and only 60% ± 10% of regional annual ablation was compensated by accumulation. Even without 21st century warming, 21% ± 1% of ice volume will be lost by 2100 due to current climatic-geometric imbalance, representing a reduction in glacier ablation into rivers of 28% ± 1%. The ablation of glaciers in the Himalayas and Tien Shan was mostly unsustainable and ice volume in these regions will reduce by at least 30% by 2100. The most important and vulnerable glacier-fed river basins (Amu Darya, Indus, Syr Darya, Tarim Interior) were supplied with >50% sustainable glacier ablation but will see long-term reductions in ice mass and glacier meltwater supply regardless of the Karakoram Anomaly.","lang":"eng"}],"volume":12,"extern":"1"},{"article_type":"original","publisher":"Springer","file_date_updated":"2021-12-17T11:34:50Z","quality_controlled":"1","ec_funded":1,"intvolume":"        12","title":"Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses","article_processing_charge":"No","department":[{"_id":"PeJo"}],"date_created":"2021-08-06T07:22:55Z","publication_status":"published","issue":"1","author":[{"id":"3AE48E0A-F248-11E8-B48F-1D18A9856A87","last_name":"Vandael","first_name":"David H","full_name":"Vandael, David H","orcid":"0000-0001-7577-1676"},{"id":"3337E116-F248-11E8-B48F-1D18A9856A87","first_name":"Yuji","last_name":"Okamoto","orcid":"0000-0003-0408-6094","full_name":"Okamoto, Yuji"},{"first_name":"Peter M","last_name":"Jonas","orcid":"0000-0001-5001-4804","full_name":"Jonas, Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"}],"scopus_import":"1","_id":"9778","ddc":["570"],"acknowledgement":"We thank Drs. Carolina Borges-Merjane and Jose Guzman for critically reading the manuscript, and Pablo Castillo for discussions. We are grateful to Alois Schlögl for help with analysis, Florian Marr for excellent technical assistance and cell reconstruction, Christina Altmutter for technical help, Eleftheria Kralli-Beller for manuscript editing, and the Scientific Service Units of IST Austria for support. This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No 692692) and the Fond zur Förderung der Wissenschaftlichen Forschung (Z 312-B27, Wittgenstein award), both to P.J.","volume":12,"abstract":[{"text":"The hippocampal mossy fiber synapse is a key synapse of the trisynaptic circuit. Post-tetanic potentiation (PTP) is the most powerful form of plasticity at this synaptic connection. It is widely believed that mossy fiber PTP is an entirely presynaptic phenomenon, implying that PTP induction is input-specific, and requires neither activity of multiple inputs nor stimulation of postsynaptic neurons. To directly test cooperativity and associativity, we made paired recordings between single mossy fiber terminals and postsynaptic CA3 pyramidal neurons in rat brain slices. By stimulating non-overlapping mossy fiber inputs converging onto single CA3 neurons, we confirm that PTP is input-specific and non-cooperative. Unexpectedly, mossy fiber PTP exhibits anti-associative induction properties. EPSCs show only minimal PTP after combined pre- and postsynaptic high-frequency stimulation with intact postsynaptic Ca2+ signaling, but marked PTP in the absence of postsynaptic spiking and after suppression of postsynaptic Ca2+ signaling (10 mM EGTA). PTP is largely recovered by inhibitors of voltage-gated R- and L-type Ca2+ channels, group II mGluRs, and vacuolar-type H+-ATPase, suggesting the involvement of retrograde vesicular glutamate signaling. Transsynaptic regulation of PTP extends the repertoire of synaptic computations, implementing a brake on mossy fiber detonation and a “smart teacher” function of hippocampal mossy fiber synapses.","lang":"eng"}],"day":"18","doi":"10.1038/s41467-021-23153-5","external_id":{"isi":["000655481800014"]},"isi":1,"citation":{"ama":"Vandael DH, Okamoto Y, Jonas PM. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. <i>Nature Communications</i>. 2021;12(1). doi:<a href=\"https://doi.org/10.1038/s41467-021-23153-5\">10.1038/s41467-021-23153-5</a>","apa":"Vandael, D. H., Okamoto, Y., &#38; Jonas, P. M. (2021). Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. <i>Nature Communications</i>. Springer. <a href=\"https://doi.org/10.1038/s41467-021-23153-5\">https://doi.org/10.1038/s41467-021-23153-5</a>","ieee":"D. H. Vandael, Y. Okamoto, and P. M. Jonas, “Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses,” <i>Nature Communications</i>, vol. 12, no. 1. Springer, 2021.","chicago":"Vandael, David H, Yuji Okamoto, and Peter M Jonas. “Transsynaptic Modulation of Presynaptic Short-Term Plasticity in Hippocampal Mossy Fiber Synapses.” <i>Nature Communications</i>. Springer, 2021. <a href=\"https://doi.org/10.1038/s41467-021-23153-5\">https://doi.org/10.1038/s41467-021-23153-5</a>.","short":"D.H. Vandael, Y. Okamoto, P.M. Jonas, Nature Communications 12 (2021).","mla":"Vandael, David H., et al. “Transsynaptic Modulation of Presynaptic Short-Term Plasticity in Hippocampal Mossy Fiber Synapses.” <i>Nature Communications</i>, vol. 12, no. 1, 2912, Springer, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-23153-5\">10.1038/s41467-021-23153-5</a>.","ista":"Vandael DH, Okamoto Y, Jonas PM. 2021. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. Nature Communications. 12(1), 2912."},"year":"2021","date_updated":"2023-08-10T14:16:16Z","keyword":["general physics and astronomy","general biochemistry","genetics and molecular biology","general chemistry"],"language":[{"iso":"eng"}],"article_number":"2912","month":"05","project":[{"call_identifier":"H2020","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","name":"Biophysics and circuit function of a giant cortical glumatergic synapse","grant_number":"692692"},{"name":"The Wittgenstein Prize","grant_number":"Z00312","call_identifier":"FWF","_id":"25C5A090-B435-11E9-9278-68D0E5697425"}],"acknowledged_ssus":[{"_id":"SSU"}],"oa_version":"Published Version","has_accepted_license":"1","publication":"Nature Communications","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","related_material":{"link":[{"url":"https://ist.ac.at/en/news/synaptic-transmission-not-a-one-way-street/","relation":"press_release","description":"News on IST Homepage"}]},"file":[{"relation":"main_file","success":1,"access_level":"open_access","file_id":"10563","creator":"kschuh","date_created":"2021-12-17T11:34:50Z","file_size":3108845,"checksum":"6036a8cdae95e1707c2a04d54e325ff4","date_updated":"2021-12-17T11:34:50Z","file_name":"2021_NatureCommunications_Vandael.pdf","content_type":"application/pdf"}],"oa":1,"publication_identifier":{"issn":["2041-1723"]},"type":"journal_article","date_published":"2021-05-18T00:00:00Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"type":"journal_article","date_published":"2020-07-01T00:00:00Z","publication_identifier":{"issn":["1530-6984"],"eissn":["1530-6992"]},"oa":1,"main_file_link":[{"url":"https://arxiv.org/abs/2004.14599","open_access":"1"}],"status":"public","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publication":"Nano Letters","oa_version":"Preprint","month":"07","keyword":["Mechanical Engineering","Condensed Matter Physics","General Materials Science","General Chemistry","Bioengineering"],"language":[{"iso":"eng"}],"year":"2020","citation":{"apa":"Duan, J., Capote-Robayna, N., Taboada-Gutiérrez, J., Álvarez-Pérez, G., Prieto Gonzalez, I., Martín-Sánchez, J., … Alonso-González, P. (2020). Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.0c01673\">https://doi.org/10.1021/acs.nanolett.0c01673</a>","ama":"Duan J, Capote-Robayna N, Taboada-Gutiérrez J, et al. Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs. <i>Nano Letters</i>. 2020;20(7):5323-5329. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.0c01673\">10.1021/acs.nanolett.0c01673</a>","chicago":"Duan, Jiahua, Nathaniel Capote-Robayna, Javier Taboada-Gutiérrez, Gonzalo Álvarez-Pérez, Ivan Prieto Gonzalez, Javier Martín-Sánchez, Alexey Y. Nikitin, and Pablo Alonso-González. “Twisted Nano-Optics: Manipulating Light at the Nanoscale with Twisted Phonon Polaritonic Slabs.” <i>Nano Letters</i>. American Chemical Society, 2020. <a href=\"https://doi.org/10.1021/acs.nanolett.0c01673\">https://doi.org/10.1021/acs.nanolett.0c01673</a>.","ieee":"J. Duan <i>et al.</i>, “Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs,” <i>Nano Letters</i>, vol. 20, no. 7. American Chemical Society, pp. 5323–5329, 2020.","mla":"Duan, Jiahua, et al. “Twisted Nano-Optics: Manipulating Light at the Nanoscale with Twisted Phonon Polaritonic Slabs.” <i>Nano Letters</i>, vol. 20, no. 7, American Chemical Society, 2020, pp. 5323–29, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.0c01673\">10.1021/acs.nanolett.0c01673</a>.","short":"J. Duan, N. Capote-Robayna, J. Taboada-Gutiérrez, G. Álvarez-Pérez, I. Prieto Gonzalez, J. Martín-Sánchez, A.Y. Nikitin, P. Alonso-González, Nano Letters 20 (2020) 5323–5329.","ista":"Duan J, Capote-Robayna N, Taboada-Gutiérrez J, Álvarez-Pérez G, Prieto Gonzalez I, Martín-Sánchez J, Nikitin AY, Alonso-González P. 2020. Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs. Nano Letters. 20(7), 5323–5329."},"date_updated":"2023-09-05T12:05:58Z","external_id":{"arxiv":["2004.14599"],"isi":["000548893200082"],"pmid":["32530634"]},"isi":1,"day":"01","arxiv":1,"doi":"10.1021/acs.nanolett.0c01673","abstract":[{"text":"Recent discoveries have shown that, when two layers of van der Waals (vdW) materials are superimposed with a relative twist angle between them, the electronic properties of the coupled system can be dramatically altered. Here, we demonstrate that a similar concept can be extended to the optics realm, particularly to propagating phonon polaritons–hybrid light-matter interactions. To do this, we fabricate stacks composed of two twisted slabs of a vdW crystal (α-MoO3) supporting anisotropic phonon polaritons (PhPs), and image the propagation of the latter when launched by localized sources. Our images reveal that, under a critical angle, the PhPs isofrequency curve undergoes a topological transition, in which the propagation of PhPs is strongly guided (canalization regime) along predetermined directions without geometric spreading. These results demonstrate a new degree of freedom (twist angle) for controlling the propagation of polaritons at the nanoscale with potential for nanoimaging, (bio)-sensing, or heat management.","lang":"eng"}],"acknowledgement":"J.T.-G. and G.Á.-P. acknowledge support through the Severo Ochoa Program from the\r\nGovernment of the Principality of Asturias (nos. PA-18-PF-BP17-126 and PA20-PF-BP19-053,\r\nrespectively). J. M-S acknowledges financial support through the Ramón y Cajal Program from\r\nthe Government of Spain (RYC2018-026196-I). A.Y.N. acknowledges the Spanish Ministry of\r\nScience, Innovation and Universities (national project no. MAT201788358-C3-3-R). P.A.-G.\r\nacknowledges support from the European Research Council under starting grant no. 715496,\r\n2DNANOPTICA.","volume":20,"scopus_import":"1","pmid":1,"_id":"10866","issue":"7","author":[{"first_name":"Jiahua","last_name":"Duan","full_name":"Duan, Jiahua"},{"last_name":"Capote-Robayna","first_name":"Nathaniel","full_name":"Capote-Robayna, Nathaniel"},{"last_name":"Taboada-Gutiérrez","first_name":"Javier","full_name":"Taboada-Gutiérrez, Javier"},{"full_name":"Álvarez-Pérez, Gonzalo","last_name":"Álvarez-Pérez","first_name":"Gonzalo"},{"orcid":"0000-0002-7370-5357","full_name":"Prieto Gonzalez, Ivan","first_name":"Ivan","last_name":"Prieto Gonzalez","id":"2A307FE2-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Martín-Sánchez, Javier","last_name":"Martín-Sánchez","first_name":"Javier"},{"first_name":"Alexey Y.","last_name":"Nikitin","full_name":"Nikitin, Alexey Y."},{"full_name":"Alonso-González, Pablo","first_name":"Pablo","last_name":"Alonso-González"}],"date_created":"2022-03-18T11:37:38Z","department":[{"_id":"NanoFab"}],"article_processing_charge":"No","publication_status":"published","intvolume":"        20","title":"Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs","quality_controlled":"1","page":"5323-5329","publisher":"American Chemical Society","article_type":"original"},{"file":[{"date_updated":"2020-09-18T13:02:37Z","file_name":"2020_NatureComm_Arnold.pdf","content_type":"application/pdf","date_created":"2020-09-18T13:02:37Z","checksum":"88f92544889eb18bb38e25629a422a86","file_size":1002818,"file_id":"8530","creator":"dernst","access_level":"open_access","relation":"main_file","success":1}],"status":"public","related_material":{"record":[{"status":"public","id":"13056","relation":"research_data"}],"link":[{"url":"https://doi.org/10.1038/s41467-020-18912-9","relation":"erratum"},{"url":"https://ist.ac.at/en/news/how-to-transport-microwave-quantum-information-via-optical-fiber/","description":"News on IST Homepage","relation":"press_release"}]},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"journal_article","date_published":"2020-09-08T00:00:00Z","publication_identifier":{"issn":["2041-1723"]},"oa":1,"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"language":[{"iso":"eng"}],"has_accepted_license":"1","publication":"Nature Communications","project":[{"call_identifier":"H2020","_id":"257EB838-B435-11E9-9278-68D0E5697425","name":"Hybrid Optomechanical Technologies","grant_number":"732894"},{"name":"A Fiber Optic Transceiver for Superconducting Qubits","grant_number":"758053","_id":"26336814-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"name":"Quantum readout techniques and technologies","grant_number":"862644","call_identifier":"H2020","_id":"237CBA6C-32DE-11EA-91FC-C7463DDC885E"},{"name":"Coherent on-chip conversion of superconducting qubit signals from microwaves to optical frequencies","_id":"2671EB66-B435-11E9-9278-68D0E5697425"}],"acknowledged_ssus":[{"_id":"NanoFab"}],"oa_version":"Published Version","article_number":"4460","month":"09","acknowledgement":"We thank Yuan Chen for performing supplementary FEM simulations and Andrew Higginbotham, Ralf Riedinger, Sungkun Hong, and Lorenzo Magrini for valuable discussions. This work was supported by IST Austria, the IST nanofabrication facility (NFF), the European Union’s Horizon 2020 research and innovation program under grant agreement no. 732894 (FET Proactive HOT) and the European Research Council under grant agreement no. 758053 (ERC StG QUNNECT). G.A. is the recipient of a DOC fellowship of the Austrian Academy of Sciences at IST Austria. W.H. is the recipient of an ISTplus postdoctoral fellowship with funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement no. 754411. J.M.F. acknowledges support from the Austrian Science Fund (FWF) through BeyondC (F71), a NOMIS foundation research grant, and the EU’s Horizon 2020 research and innovation program under grant agreement no. 862644 (FET Open QUARTET).","volume":11,"ddc":["530"],"year":"2020","citation":{"ieee":"G. M. Arnold <i>et al.</i>, “Converting microwave and telecom photons with a silicon photonic nanomechanical interface,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","chicago":"Arnold, Georg M, Matthias Wulf, Shabir Barzanjeh, Elena Redchenko, Alfredo R Rueda Sanchez, William J Hease, Farid Hassani, and Johannes M Fink. “Converting Microwave and Telecom Photons with a Silicon Photonic Nanomechanical Interface.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-18269-z\">https://doi.org/10.1038/s41467-020-18269-z</a>.","apa":"Arnold, G. M., Wulf, M., Barzanjeh, S., Redchenko, E., Rueda Sanchez, A. R., Hease, W. J., … Fink, J. M. (2020). Converting microwave and telecom photons with a silicon photonic nanomechanical interface. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-18269-z\">https://doi.org/10.1038/s41467-020-18269-z</a>","ama":"Arnold GM, Wulf M, Barzanjeh S, et al. Converting microwave and telecom photons with a silicon photonic nanomechanical interface. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-18269-z\">10.1038/s41467-020-18269-z</a>","ista":"Arnold GM, Wulf M, Barzanjeh S, Redchenko E, Rueda Sanchez AR, Hease WJ, Hassani F, Fink JM. 2020. Converting microwave and telecom photons with a silicon photonic nanomechanical interface. Nature Communications. 11, 4460.","short":"G.M. Arnold, M. Wulf, S. Barzanjeh, E. Redchenko, A.R. Rueda Sanchez, W.J. Hease, F. Hassani, J.M. Fink, Nature Communications 11 (2020).","mla":"Arnold, Georg M., et al. “Converting Microwave and Telecom Photons with a Silicon Photonic Nanomechanical Interface.” <i>Nature Communications</i>, vol. 11, 4460, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-18269-z\">10.1038/s41467-020-18269-z</a>."},"date_updated":"2024-08-07T07:11:51Z","external_id":{"isi":["000577280200001"]},"isi":1,"day":"08","doi":"10.1038/s41467-020-18269-z","abstract":[{"lang":"eng","text":"Practical quantum networks require low-loss and noise-resilient optical interconnects as well as non-Gaussian resources for entanglement distillation and distributed quantum computation. The latter could be provided by superconducting circuits but existing solutions to interface the microwave and optical domains lack either scalability or efficiency, and in most cases the conversion noise is not known. In this work we utilize the unique opportunities of silicon photonics, cavity optomechanics and superconducting circuits to demonstrate a fully integrated, coherent transducer interfacing the microwave X and the telecom S bands with a total (internal) bidirectional transduction efficiency of 1.2% (135%) at millikelvin temperatures. The coupling relies solely on the radiation pressure interaction mediated by the femtometer-scale motion of two silicon nanobeams reaching a <jats:italic>V</jats:italic><jats:sub><jats:italic>π</jats:italic></jats:sub> as low as 16 μV for sub-nanowatt pump powers. Without the associated optomechanical gain, we achieve a total (internal) pure conversion efficiency of up to 0.019% (1.6%), relevant for future noise-free operation on this qubit-compatible platform."}],"ec_funded":1,"quality_controlled":"1","file_date_updated":"2020-09-18T13:02:37Z","publisher":"Springer Nature","article_type":"original","_id":"8529","author":[{"full_name":"Arnold, Georg M","orcid":"0000-0003-1397-7876","last_name":"Arnold","first_name":"Georg M","id":"3770C838-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Wulf","first_name":"Matthias","full_name":"Wulf, Matthias","orcid":"0000-0001-6613-1378","id":"45598606-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Barzanjeh, Shabir","orcid":"0000-0003-0415-1423","last_name":"Barzanjeh","first_name":"Shabir","id":"2D25E1F6-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Redchenko","first_name":"Elena","full_name":"Redchenko, Elena","id":"2C21D6E8-F248-11E8-B48F-1D18A9856A87"},{"id":"3B82B0F8-F248-11E8-B48F-1D18A9856A87","first_name":"Alfredo R","last_name":"Rueda Sanchez","orcid":"0000-0001-6249-5860","full_name":"Rueda Sanchez, Alfredo R"},{"id":"29705398-F248-11E8-B48F-1D18A9856A87","last_name":"Hease","first_name":"William J","full_name":"Hease, William J","orcid":"0000-0001-9868-2166"},{"orcid":"0000-0001-6937-5773","full_name":"Hassani, Farid","first_name":"Farid","last_name":"Hassani","id":"2AED110C-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Johannes M","last_name":"Fink","orcid":"0000-0001-8112-028X","full_name":"Fink, Johannes M","id":"4B591CBA-F248-11E8-B48F-1D18A9856A87"}],"date_created":"2020-09-18T10:56:20Z","department":[{"_id":"JoFi"}],"article_processing_charge":"No","publication_status":"published","intvolume":"        11","title":"Converting microwave and telecom photons with a silicon photonic nanomechanical interface"},{"language":[{"iso":"eng"}],"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"month":"09","article_number":"4838","oa_version":"Published Version","publication":"Nature Communications","has_accepted_license":"1","related_material":{"link":[{"url":"https://doi.org/10.1038/s41467-020-19720-x","relation":"erratum"}]},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","file":[{"date_created":"2020-09-28T13:16:15Z","file_size":1822469,"checksum":"eada7bc8dd16a49390137cff882ef328","date_updated":"2020-09-28T13:16:15Z","content_type":"application/pdf","file_name":"2020_NatureComm_Prehal.pdf","relation":"main_file","success":1,"access_level":"open_access","file_id":"8585","creator":"dernst"}],"oa":1,"publication_identifier":{"issn":["2041-1723"]},"date_published":"2020-09-24T00:00:00Z","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","publisher":"Springer Nature","file_date_updated":"2020-09-28T13:16:15Z","quality_controlled":"1","title":"Persistent and reversible solid iodine electrodeposition in nanoporous carbons","intvolume":"        11","publication_status":"published","article_processing_charge":"No","department":[{"_id":"StFr"}],"date_created":"2020-09-25T07:23:13Z","author":[{"full_name":"Prehal, Christian","last_name":"Prehal","first_name":"Christian"},{"full_name":"Fitzek, Harald","first_name":"Harald","last_name":"Fitzek"},{"full_name":"Kothleitner, Gerald","first_name":"Gerald","last_name":"Kothleitner"},{"full_name":"Presser, Volker","last_name":"Presser","first_name":"Volker"},{"last_name":"Gollas","first_name":"Bernhard","full_name":"Gollas, Bernhard"},{"id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","orcid":"0000-0003-2902-5319","full_name":"Freunberger, Stefan Alexander","first_name":"Stefan Alexander","last_name":"Freunberger"},{"last_name":"Abbas","first_name":"Qamar","full_name":"Abbas, Qamar"}],"_id":"8568","ddc":["530"],"volume":11,"abstract":[{"lang":"eng","text":"Aqueous iodine based electrochemical energy storage is considered a potential candidate to improve sustainability and performance of current battery and supercapacitor technology. It harnesses the redox activity of iodide, iodine, and polyiodide species in the confined geometry of nanoporous carbon electrodes. However, current descriptions of the electrochemical reaction mechanism to interconvert these species are elusive. Here we show that electrochemical oxidation of iodide in nanoporous carbons forms persistent solid iodine deposits. Confinement slows down dissolution into triiodide and pentaiodide, responsible for otherwise significant self-discharge via shuttling. The main tools for these insights are in situ Raman spectroscopy and in situ small and wide-angle X-ray scattering (in situ SAXS/WAXS). In situ Raman confirms the reversible formation of triiodide and pentaiodide. In situ SAXS/WAXS indicates remarkable amounts of solid iodine deposited in the carbon nanopores. Combined with stochastic modeling, in situ SAXS allows quantifying the solid iodine volume fraction and visualizing the iodine structure on 3D lattice models at the sub-nanometer scale. Based on the derived mechanism, we demonstrate strategies for improved iodine pore filling capacity and prevention of self-discharge, applicable to hybrid supercapacitors and batteries."}],"doi":"10.1038/s41467-020-18610-6","day":"24","isi":1,"external_id":{"isi":["000573756600004"]},"date_updated":"2023-08-22T09:37:24Z","citation":{"short":"C. Prehal, H. Fitzek, G. Kothleitner, V. Presser, B. Gollas, S.A. Freunberger, Q. Abbas, Nature Communications 11 (2020).","mla":"Prehal, Christian, et al. “Persistent and Reversible Solid Iodine Electrodeposition in Nanoporous Carbons.” <i>Nature Communications</i>, vol. 11, 4838, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-18610-6\">10.1038/s41467-020-18610-6</a>.","ista":"Prehal C, Fitzek H, Kothleitner G, Presser V, Gollas B, Freunberger SA, Abbas Q. 2020. Persistent and reversible solid iodine electrodeposition in nanoporous carbons. Nature Communications. 11, 4838.","ama":"Prehal C, Fitzek H, Kothleitner G, et al. Persistent and reversible solid iodine electrodeposition in nanoporous carbons. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-18610-6\">10.1038/s41467-020-18610-6</a>","apa":"Prehal, C., Fitzek, H., Kothleitner, G., Presser, V., Gollas, B., Freunberger, S. A., &#38; Abbas, Q. (2020). Persistent and reversible solid iodine electrodeposition in nanoporous carbons. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-18610-6\">https://doi.org/10.1038/s41467-020-18610-6</a>","ieee":"C. Prehal <i>et al.</i>, “Persistent and reversible solid iodine electrodeposition in nanoporous carbons,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","chicago":"Prehal, Christian, Harald Fitzek, Gerald Kothleitner, Volker Presser, Bernhard Gollas, Stefan Alexander Freunberger, and Qamar Abbas. “Persistent and Reversible Solid Iodine Electrodeposition in Nanoporous Carbons.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-18610-6\">https://doi.org/10.1038/s41467-020-18610-6</a>."},"year":"2020"},{"publication_identifier":{"issn":["2041-1723"]},"oa":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"journal_article","date_published":"2020-11-04T00:00:00Z","file":[{"date_created":"2020-11-09T07:56:24Z","file_size":1670898,"checksum":"b2688f0347e69e6629bba582077278c5","date_updated":"2020-11-09T07:56:24Z","file_name":"2020_NatureComm_Schulte.pdf","content_type":"application/pdf","access_level":"open_access","relation":"main_file","success":1,"file_id":"8745","creator":"dernst"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","oa_version":"Published Version","article_number":"5569","month":"11","has_accepted_license":"1","publication":"Nature Communications","keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"language":[{"iso":"eng"}],"day":"04","doi":"10.1038/s41467-020-19372-x","abstract":[{"text":"Understanding the conformational sampling of translation-arrested ribosome nascent chain complexes is key to understand co-translational folding. Up to now, coupling of cysteine oxidation, disulfide bond formation and structure formation in nascent chains has remained elusive. Here, we investigate the eye-lens protein γB-crystallin in the ribosomal exit tunnel. Using mass spectrometry, theoretical simulations, dynamic nuclear polarization-enhanced solid-state nuclear magnetic resonance and cryo-electron microscopy, we show that thiol groups of cysteine residues undergo S-glutathionylation and S-nitrosylation and form non-native disulfide bonds. Thus, covalent modification chemistry occurs already prior to nascent chain release as the ribosome exit tunnel provides sufficient space even for disulfide bond formation which can guide protein folding.","lang":"eng"}],"citation":{"chicago":"Schulte, Linda, Jiafei Mao, Julian Reitz, Sridhar Sreeramulu, Denis Kudlinzki, Victor-Valentin Hodirnau, Jakob Meier-Credo, et al. “Cysteine Oxidation and Disulfide Formation in the Ribosomal Exit Tunnel.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-19372-x\">https://doi.org/10.1038/s41467-020-19372-x</a>.","ieee":"L. Schulte <i>et al.</i>, “Cysteine oxidation and disulfide formation in the ribosomal exit tunnel,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","ama":"Schulte L, Mao J, Reitz J, et al. Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-19372-x\">10.1038/s41467-020-19372-x</a>","apa":"Schulte, L., Mao, J., Reitz, J., Sreeramulu, S., Kudlinzki, D., Hodirnau, V.-V., … Schwalbe, H. (2020). Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-19372-x\">https://doi.org/10.1038/s41467-020-19372-x</a>","ista":"Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D, Hodirnau V-V, Meier-Credo J, Saxena K, Buhr F, Langer JD, Blackledge M, Frangakis AS, Glaubitz C, Schwalbe H. 2020. Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. Nature Communications. 11, 5569.","mla":"Schulte, Linda, et al. “Cysteine Oxidation and Disulfide Formation in the Ribosomal Exit Tunnel.” <i>Nature Communications</i>, vol. 11, 5569, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-19372-x\">10.1038/s41467-020-19372-x</a>.","short":"L. Schulte, J. Mao, J. Reitz, S. Sreeramulu, D. Kudlinzki, V.-V. Hodirnau, J. Meier-Credo, K. Saxena, F. Buhr, J.D. Langer, M. Blackledge, A.S. Frangakis, C. Glaubitz, H. Schwalbe, Nature Communications 11 (2020)."},"year":"2020","date_updated":"2023-08-22T12:36:07Z","external_id":{"isi":["000592028600001"]},"isi":1,"volume":11,"acknowledgement":"We acknowledge help from Anja Seybert, Margot Frangakis, Diana Grewe, Mikhail Eltsov, Utz Ermel, and Shintaro Aibara. The work was supported by Deutsche Forschungsgemeinschaft in the CLiC graduate school. Work at the Center for Biomolecular Magnetic Resonance (BMRZ) is supported by the German state of Hesse. The work at BMRZ has been supported by the state of Hesse. L.S. has been supported by the DFG graduate college: CLiC.","ddc":["570"],"article_processing_charge":"No","department":[{"_id":"EM-Fac"}],"date_created":"2020-11-09T07:49:36Z","publication_status":"published","intvolume":"        11","title":"Cysteine oxidation and disulfide formation in the ribosomal exit tunnel","scopus_import":"1","_id":"8744","author":[{"full_name":"Schulte, Linda","first_name":"Linda","last_name":"Schulte"},{"last_name":"Mao","first_name":"Jiafei","full_name":"Mao, Jiafei"},{"first_name":"Julian","last_name":"Reitz","full_name":"Reitz, Julian"},{"full_name":"Sreeramulu, Sridhar","first_name":"Sridhar","last_name":"Sreeramulu"},{"last_name":"Kudlinzki","first_name":"Denis","full_name":"Kudlinzki, Denis"},{"full_name":"Hodirnau, Victor-Valentin","first_name":"Victor-Valentin","last_name":"Hodirnau","id":"3661B498-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Meier-Credo, Jakob","last_name":"Meier-Credo","first_name":"Jakob"},{"full_name":"Saxena, Krishna","first_name":"Krishna","last_name":"Saxena"},{"last_name":"Buhr","first_name":"Florian","full_name":"Buhr, Florian"},{"first_name":"Julian D.","last_name":"Langer","full_name":"Langer, Julian D."},{"full_name":"Blackledge, Martin","last_name":"Blackledge","first_name":"Martin"},{"first_name":"Achilleas S.","last_name":"Frangakis","full_name":"Frangakis, Achilleas S."},{"full_name":"Glaubitz, Clemens","first_name":"Clemens","last_name":"Glaubitz"},{"last_name":"Schwalbe","first_name":"Harald","full_name":"Schwalbe, Harald"}],"publisher":"Springer Nature","article_type":"original","quality_controlled":"1","file_date_updated":"2020-11-09T07:56:24Z"}]