---
_id: '8402'
abstract:
- lang: eng
text: "Background: The mitochondrial pyruvate carrier (MPC) plays a central role
in energy metabolism by transporting pyruvate across the inner mitochondrial membrane.
Its heterodimeric composition and homology to SWEET and semiSWEET transporters
set the MPC apart from the canonical mitochondrial carrier family (named MCF or
SLC25). The import of the canonical carriers is mediated by the carrier translocase
of the inner membrane (TIM22) pathway and is dependent on their structure, which
features an even number of transmembrane segments and both termini in the intermembrane
space. The import pathway of MPC proteins has not been elucidated. The odd number
of transmembrane segments and positioning of the N-terminus in the matrix argues
against an import via the TIM22 carrier pathway but favors an import via the flexible
presequence pathway.\r\nResults: Here, we systematically analyzed the import pathways
of Mpc2 and Mpc3 and report that, contrary to an expected import via the flexible
presequence pathway, yeast MPC proteins with an odd number of transmembrane segments
and matrix-exposed N-terminus are imported by the carrier pathway, using the receptor
Tom70, small TIM chaperones, and the TIM22 complex. The TIM9·10 complex chaperones
MPC proteins through the mitochondrial intermembrane space using conserved hydrophobic
motifs that are also required for the interaction with canonical carrier proteins.\r\nConclusions:
The carrier pathway can import paired and non-paired transmembrane helices and
translocate N-termini to either side of the mitochondrial inner membrane, revealing
an unexpected versatility of the mitochondrial import pathway for non-cleavable
inner membrane proteins."
article_number: '2'
article_processing_charge: No
article_type: original
author:
- first_name: Heike
full_name: Rampelt, Heike
last_name: Rampelt
- first_name: Iva
full_name: Sucec, Iva
last_name: Sucec
- first_name: Beate
full_name: Bersch, Beate
last_name: Bersch
- first_name: Patrick
full_name: Horten, Patrick
last_name: Horten
- first_name: Inge
full_name: Perschil, Inge
last_name: Perschil
- first_name: Jean-Claude
full_name: Martinou, Jean-Claude
last_name: Martinou
- first_name: Martin
full_name: van der Laan, Martin
last_name: van der Laan
- first_name: Nils
full_name: Wiedemann, Nils
last_name: Wiedemann
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Nikolaus
full_name: Pfanner, Nikolaus
last_name: Pfanner
citation:
ama: Rampelt H, Sucec I, Bersch B, et al. The mitochondrial carrier pathway transports
non-canonical substrates with an odd number of transmembrane segments. BMC
Biology. 2020;18. doi:10.1186/s12915-019-0733-6
apa: Rampelt, H., Sucec, I., Bersch, B., Horten, P., Perschil, I., Martinou, J.-C.,
… Pfanner, N. (2020). The mitochondrial carrier pathway transports non-canonical
substrates with an odd number of transmembrane segments. BMC Biology. Springer
Nature. https://doi.org/10.1186/s12915-019-0733-6
chicago: Rampelt, Heike, Iva Sucec, Beate Bersch, Patrick Horten, Inge Perschil,
Jean-Claude Martinou, Martin van der Laan, Nils Wiedemann, Paul Schanda, and Nikolaus
Pfanner. “The Mitochondrial Carrier Pathway Transports Non-Canonical Substrates
with an Odd Number of Transmembrane Segments.” BMC Biology. Springer Nature,
2020. https://doi.org/10.1186/s12915-019-0733-6.
ieee: H. Rampelt et al., “The mitochondrial carrier pathway transports non-canonical
substrates with an odd number of transmembrane segments,” BMC Biology,
vol. 18. Springer Nature, 2020.
ista: Rampelt H, Sucec I, Bersch B, Horten P, Perschil I, Martinou J-C, van der
Laan M, Wiedemann N, Schanda P, Pfanner N. 2020. The mitochondrial carrier pathway
transports non-canonical substrates with an odd number of transmembrane segments.
BMC Biology. 18, 2.
mla: Rampelt, Heike, et al. “The Mitochondrial Carrier Pathway Transports Non-Canonical
Substrates with an Odd Number of Transmembrane Segments.” BMC Biology,
vol. 18, 2, Springer Nature, 2020, doi:10.1186/s12915-019-0733-6.
short: H. Rampelt, I. Sucec, B. Bersch, P. Horten, I. Perschil, J.-C. Martinou,
M. van der Laan, N. Wiedemann, P. Schanda, N. Pfanner, BMC Biology 18 (2020).
date_created: 2020-09-17T10:26:53Z
date_published: 2020-01-06T00:00:00Z
date_updated: 2021-01-12T08:19:02Z
day: '06'
doi: 10.1186/s12915-019-0733-6
extern: '1'
external_id:
pmid:
- '31907035'
intvolume: ' 18'
keyword:
- Biotechnology
- Plant Science
- General Biochemistry
- Genetics and Molecular Biology
- Developmental Biology
- Cell Biology
- Physiology
- Ecology
- Evolution
- Behavior and Systematics
- Structural Biology
- General Agricultural and Biological Sciences
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1186/s12915-019-0733-6
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: BMC Biology
publication_identifier:
issn:
- 1741-7007
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: The mitochondrial carrier pathway transports non-canonical substrates with
an odd number of transmembrane segments
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2020'
...
---
_id: '8767'
abstract:
- lang: eng
text: Resources are rarely distributed uniformly within a population. Heterogeneity
in the concentration of a drug, the quality of breeding sites, or wealth can all
affect evolutionary dynamics. In this study, we represent a collection of properties
affecting the fitness at a given location using a color. A green node is rich
in resources while a red node is poorer. More colors can represent a broader spectrum
of resource qualities. For a population evolving according to the birth-death
Moran model, the first question we address is which structures, identified by
graph connectivity and graph coloring, are evolutionarily equivalent. We prove
that all properly two-colored, undirected, regular graphs are evolutionarily equivalent
(where “properly colored” means that no two neighbors have the same color). We
then compare the effects of background heterogeneity on properly two-colored graphs
to those with alternative schemes in which the colors are permuted. Finally, we
discuss dynamic coloring as a model for spatiotemporal resource fluctuations,
and we illustrate that random dynamic colorings often diminish the effects of
background heterogeneity relative to a proper two-coloring.
acknowledgement: 'We thank Igor Erovenko for many helpful comments on an earlier version
of this paper. : Army Research Laboratory (grant W911NF-18-2-0265) (M.A.N.); the
Bill & Melinda Gates Foundation (grant OPP1148627) (M.A.N.); the NVIDIA Corporation
(A.M.). The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.'
article_number: e1008402
article_processing_charge: No
article_type: original
author:
- first_name: Kamran
full_name: Kaveh, Kamran
last_name: Kaveh
- first_name: Alex
full_name: McAvoy, Alex
last_name: McAvoy
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin A.
full_name: Nowak, Martin A.
last_name: Nowak
citation:
ama: Kaveh K, McAvoy A, Chatterjee K, Nowak MA. The Moran process on 2-chromatic
graphs. PLOS Computational Biology. 2020;16(11). doi:10.1371/journal.pcbi.1008402
apa: Kaveh, K., McAvoy, A., Chatterjee, K., & Nowak, M. A. (2020). The Moran
process on 2-chromatic graphs. PLOS Computational Biology. Public Library
of Science. https://doi.org/10.1371/journal.pcbi.1008402
chicago: Kaveh, Kamran, Alex McAvoy, Krishnendu Chatterjee, and Martin A. Nowak.
“The Moran Process on 2-Chromatic Graphs.” PLOS Computational Biology.
Public Library of Science, 2020. https://doi.org/10.1371/journal.pcbi.1008402.
ieee: K. Kaveh, A. McAvoy, K. Chatterjee, and M. A. Nowak, “The Moran process on
2-chromatic graphs,” PLOS Computational Biology, vol. 16, no. 11. Public
Library of Science, 2020.
ista: Kaveh K, McAvoy A, Chatterjee K, Nowak MA. 2020. The Moran process on 2-chromatic
graphs. PLOS Computational Biology. 16(11), e1008402.
mla: Kaveh, Kamran, et al. “The Moran Process on 2-Chromatic Graphs.” PLOS Computational
Biology, vol. 16, no. 11, e1008402, Public Library of Science, 2020, doi:10.1371/journal.pcbi.1008402.
short: K. Kaveh, A. McAvoy, K. Chatterjee, M.A. Nowak, PLOS Computational Biology
16 (2020).
date_created: 2020-11-18T07:20:23Z
date_published: 2020-11-05T00:00:00Z
date_updated: 2023-08-22T12:49:18Z
day: '05'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1371/journal.pcbi.1008402
external_id:
isi:
- '000591317200004'
file:
- access_level: open_access
checksum: 555456dd0e47bcf9e0994bcb95577e88
content_type: application/pdf
creator: dernst
date_created: 2020-11-18T07:26:10Z
date_updated: 2020-11-18T07:26:10Z
file_id: '8768'
file_name: 2020_PlosCompBio_Kaveh.pdf
file_size: 2498594
relation: main_file
success: 1
file_date_updated: 2020-11-18T07:26:10Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
issue: '11'
keyword:
- Ecology
- Modelling and Simulation
- Computational Theory and Mathematics
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
- Molecular Biology
- Cellular and Molecular Neuroscience
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: PLOS Computational Biology
publication_identifier:
eissn:
- 1553-7358
issn:
- 1553-734X
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Moran process on 2-chromatic graphs
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 16
year: '2020'
...
---
_id: '12189'
abstract:
- lang: eng
text: Meiotic crossovers (COs) are important for reshuffling genetic information
between homologous chromosomes and they are essential for their correct segregation.
COs are unevenly distributed along chromosomes and the underlying mechanisms controlling
CO localization are not well understood. We previously showed that meiotic COs
are mis-localized in the absence of AXR1, an enzyme involved in the neddylation/rubylation
protein modification pathway in Arabidopsis thaliana. Here, we report that in
axr1-/-, male meiocytes show a strong defect in chromosome pairing whereas the
formation of the telomere bouquet is not affected. COs are also redistributed
towards subtelomeric chromosomal ends where they frequently form clusters, in
contrast to large central regions depleted in recombination. The CO suppressed
regions correlate with DNA hypermethylation of transposable elements (TEs) in
the CHH context in axr1-/- meiocytes. Through examining somatic methylomes, we
found axr1-/- affects DNA methylation in a plant, causing hypermethylation in
all sequence contexts (CG, CHG and CHH) in TEs. Impairment of the main pathways
involved in DNA methylation is epistatic over axr1-/- for DNA methylation in somatic
cells but does not restore regular chromosome segregation during meiosis. Collectively,
our findings reveal that the neddylation pathway not only regulates hormonal perception
and CO distribution but is also, directly or indirectly, a major limiting pathway
of TE DNA methylation in somatic cells.
acknowledgement: The authors wish to thank Cécile Raynaud, Eric Jenczewski, Rajeev
Kumar, Raphaël Mercier and Jean Molinier for critical reading of the manuscript.
article_number: e1008894
article_processing_charge: No
article_type: original
author:
- first_name: Nicolas
full_name: Christophorou, Nicolas
last_name: Christophorou
- first_name: Wenjing
full_name: She, Wenjing
last_name: She
- first_name: Jincheng
full_name: Long, Jincheng
last_name: Long
- first_name: Aurélie
full_name: Hurel, Aurélie
last_name: Hurel
- first_name: Sébastien
full_name: Beaubiat, Sébastien
last_name: Beaubiat
- first_name: Yassir
full_name: Idir, Yassir
last_name: Idir
- first_name: Marina
full_name: Tagliaro-Jahns, Marina
last_name: Tagliaro-Jahns
- first_name: Aurélie
full_name: Chambon, Aurélie
last_name: Chambon
- first_name: Victor
full_name: Solier, Victor
last_name: Solier
- first_name: Daniel
full_name: Vezon, Daniel
last_name: Vezon
- first_name: Mathilde
full_name: Grelon, Mathilde
last_name: Grelon
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
- first_name: Nicolas
full_name: Bouché, Nicolas
last_name: Bouché
- first_name: Christine
full_name: Mézard, Christine
last_name: Mézard
citation:
ama: Christophorou N, She W, Long J, et al. AXR1 affects DNA methylation independently
of its role in regulating meiotic crossover localization. PLOS Genetics.
2020;16(6). doi:10.1371/journal.pgen.1008894
apa: Christophorou, N., She, W., Long, J., Hurel, A., Beaubiat, S., Idir, Y., …
Mézard, C. (2020). AXR1 affects DNA methylation independently of its role in regulating
meiotic crossover localization. PLOS Genetics. Public Library of Science
(PLoS). https://doi.org/10.1371/journal.pgen.1008894
chicago: Christophorou, Nicolas, Wenjing She, Jincheng Long, Aurélie Hurel, Sébastien
Beaubiat, Yassir Idir, Marina Tagliaro-Jahns, et al. “AXR1 Affects DNA Methylation
Independently of Its Role in Regulating Meiotic Crossover Localization.” PLOS
Genetics. Public Library of Science (PLoS), 2020. https://doi.org/10.1371/journal.pgen.1008894.
ieee: N. Christophorou et al., “AXR1 affects DNA methylation independently
of its role in regulating meiotic crossover localization,” PLOS Genetics,
vol. 16, no. 6. Public Library of Science (PLoS), 2020.
ista: Christophorou N, She W, Long J, Hurel A, Beaubiat S, Idir Y, Tagliaro-Jahns
M, Chambon A, Solier V, Vezon D, Grelon M, Feng X, Bouché N, Mézard C. 2020. AXR1
affects DNA methylation independently of its role in regulating meiotic crossover
localization. PLOS Genetics. 16(6), e1008894.
mla: Christophorou, Nicolas, et al. “AXR1 Affects DNA Methylation Independently
of Its Role in Regulating Meiotic Crossover Localization.” PLOS Genetics,
vol. 16, no. 6, e1008894, Public Library of Science (PLoS), 2020, doi:10.1371/journal.pgen.1008894.
short: N. Christophorou, W. She, J. Long, A. Hurel, S. Beaubiat, Y. Idir, M. Tagliaro-Jahns,
A. Chambon, V. Solier, D. Vezon, M. Grelon, X. Feng, N. Bouché, C. Mézard, PLOS
Genetics 16 (2020).
date_created: 2023-01-16T09:16:10Z
date_published: 2020-06-29T00:00:00Z
date_updated: 2023-05-08T10:54:39Z
day: '29'
department:
- _id: XiFe
doi: 10.1371/journal.pgen.1008894
extern: '1'
external_id:
pmid:
- '32598340'
intvolume: ' 16'
issue: '6'
keyword:
- Cancer Research
- Genetics (clinical)
- Genetics
- Molecular Biology
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351236/
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLOS Genetics
publication_identifier:
issn:
- 1553-7404
publication_status: published
publisher: Public Library of Science (PLoS)
quality_controlled: '1'
scopus_import: '1'
status: public
title: AXR1 affects DNA methylation independently of its role in regulating meiotic
crossover localization
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2020'
...
---
_id: '10895'
abstract:
- lang: eng
text: 'Due to their sessile lifestyles, plants need to deal with the limitations
and stresses imposed by the changing environment. Plants cope with these by a
remarkable developmental flexibility, which is embedded in their strategy to survive.
Plants can adjust their size, shape and number of organs, bend according to gravity
and light, and regenerate tissues that were damaged, utilizing a coordinating,
intercellular signal, the plant hormone, auxin. Another versatile signal is the
cation, Ca2+, which is a crucial second messenger for many rapid cellular processes
during responses to a wide range of endogenous and environmental signals, such
as hormones, light, drought stress and others. Auxin is a good candidate for one
of these Ca2+-activating signals. However, the role of auxin-induced Ca2+ signaling
is poorly understood. Here, we will provide an overview of possible developmental
and physiological roles, as well as mechanisms underlying the interconnection
of Ca2+ and auxin signaling. '
article_processing_charge: No
article_type: original
author:
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: 'Vanneste S, Friml J. Calcium: The missing link in auxin action. Plants.
2013;2(4):650-675. doi:10.3390/plants2040650'
apa: 'Vanneste, S., & Friml, J. (2013). Calcium: The missing link in auxin action.
Plants. MDPI. https://doi.org/10.3390/plants2040650'
chicago: 'Vanneste, Steffen, and Jiří Friml. “Calcium: The Missing Link in Auxin
Action.” Plants. MDPI, 2013. https://doi.org/10.3390/plants2040650.'
ieee: 'S. Vanneste and J. Friml, “Calcium: The missing link in auxin action,” Plants,
vol. 2, no. 4. MDPI, pp. 650–675, 2013.'
ista: 'Vanneste S, Friml J. 2013. Calcium: The missing link in auxin action. Plants.
2(4), 650–675.'
mla: 'Vanneste, Steffen, and Jiří Friml. “Calcium: The Missing Link in Auxin Action.”
Plants, vol. 2, no. 4, MDPI, 2013, pp. 650–75, doi:10.3390/plants2040650.'
short: S. Vanneste, J. Friml, Plants 2 (2013) 650–675.
date_created: 2022-03-21T07:13:49Z
date_published: 2013-10-21T00:00:00Z
date_updated: 2022-03-21T12:15:29Z
day: '21'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.3390/plants2040650
external_id:
pmid:
- '27137397'
file:
- access_level: open_access
checksum: fb4ff2e820e344e253c9197544610be6
content_type: application/pdf
creator: dernst
date_created: 2022-03-21T12:12:56Z
date_updated: 2022-03-21T12:12:56Z
file_id: '10916'
file_name: 2013_Plants_Vanneste.pdf
file_size: 670188
relation: main_file
success: 1
file_date_updated: 2022-03-21T12:12:56Z
has_accepted_license: '1'
intvolume: ' 2'
issue: '4'
keyword:
- Plant Science
- Ecology
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
license: https://creativecommons.org/licenses/by/3.0/
month: '10'
oa: 1
oa_version: Published Version
page: 650-675
pmid: 1
publication: Plants
publication_identifier:
issn:
- 2223-7747
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Calcium: The missing link in auxin action'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
short: CC BY (3.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2013'
...
---
_id: '11086'
abstract:
- lang: eng
text: Faithful execution of developmental gene expression programs occurs at multiple
levels and involves many different components such as transcription factors, histone-modification
enzymes, and mRNA processing proteins. Recent evidence suggests that nucleoporins,
well known components that control nucleo-cytoplasmic trafficking, have wide-ranging
functions in developmental gene regulation that potentially extend beyond their
role in nuclear transport. Whether the unexpected role of nuclear pore proteins
in transcription regulation, which initially has been described in fungi and flies,
also applies to human cells is unknown. Here we show at a genome-wide level that
the nuclear pore protein NUP98 associates with developmentally regulated genes
active during human embryonic stem cell differentiation. Overexpression of a dominant
negative fragment of NUP98 levels decreases expression levels of NUP98-bound genes.
In addition, we identify two modes of developmental gene regulation by NUP98 that
are differentiated by the spatial localization of NUP98 target genes. Genes in
the initial stage of developmental induction can associate with NUP98 that is
embedded in the nuclear pores at the nuclear periphery. Alternatively, genes that
are highly induced can interact with NUP98 in the nuclear interior, away from
the nuclear pores. This work demonstrates for the first time that NUP98 dynamically
associates with the human genome during differentiation, revealing a role of a
nuclear pore protein in regulating developmental gene expression programs.
article_number: e1003308
article_processing_charge: No
article_type: original
author:
- first_name: Yun
full_name: Liang, Yun
last_name: Liang
- first_name: Tobias M.
full_name: Franks, Tobias M.
last_name: Franks
- first_name: Maria C.
full_name: Marchetto, Maria C.
last_name: Marchetto
- first_name: Fred H.
full_name: Gage, Fred H.
last_name: Gage
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Liang Y, Franks TM, Marchetto MC, Gage FH, Hetzer M. Dynamic association of
NUP98 with the human genome. PLoS Genetics. 2013;9(2). doi:10.1371/journal.pgen.1003308
apa: Liang, Y., Franks, T. M., Marchetto, M. C., Gage, F. H., & Hetzer, M. (2013).
Dynamic association of NUP98 with the human genome. PLoS Genetics. Public
Library of Science. https://doi.org/10.1371/journal.pgen.1003308
chicago: Liang, Yun, Tobias M. Franks, Maria C. Marchetto, Fred H. Gage, and Martin
Hetzer. “Dynamic Association of NUP98 with the Human Genome.” PLoS Genetics.
Public Library of Science, 2013. https://doi.org/10.1371/journal.pgen.1003308.
ieee: Y. Liang, T. M. Franks, M. C. Marchetto, F. H. Gage, and M. Hetzer, “Dynamic
association of NUP98 with the human genome,” PLoS Genetics, vol. 9, no.
2. Public Library of Science, 2013.
ista: Liang Y, Franks TM, Marchetto MC, Gage FH, Hetzer M. 2013. Dynamic association
of NUP98 with the human genome. PLoS Genetics. 9(2), e1003308.
mla: Liang, Yun, et al. “Dynamic Association of NUP98 with the Human Genome.” PLoS
Genetics, vol. 9, no. 2, e1003308, Public Library of Science, 2013, doi:10.1371/journal.pgen.1003308.
short: Y. Liang, T.M. Franks, M.C. Marchetto, F.H. Gage, M. Hetzer, PLoS Genetics
9 (2013).
date_created: 2022-04-07T07:50:59Z
date_published: 2013-02-28T00:00:00Z
date_updated: 2022-07-18T08:45:58Z
day: '28'
doi: 10.1371/journal.pgen.1003308
extern: '1'
external_id:
pmid:
- '23468646'
intvolume: ' 9'
issue: '2'
keyword:
- Cancer Research
- Genetics (clinical)
- Genetics
- Molecular Biology
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1371/journal.pgen.1003308
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Genetics
publication_identifier:
issn:
- 1553-7404
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamic association of NUP98 with the human genome
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 9
year: '2013'
...
---
_id: '12648'
abstract:
- lang: eng
text: Distributed glacier melt models generally assume that the glacier surface
consists of bare exposed ice and snow. In reality, many glaciers are wholly or
partially covered in layers of debris that tend to suppress ablation rates. In
this paper, an existing physically based point model for the ablation of debris-covered
ice is incorporated in a distributed melt model and applied to Haut Glacier d'Arolla,
Switzerland, which has three large patches of debris cover on its surface. The
model is based on a 10 m resolution digital elevation model (DEM) of the area;
each glacier pixel in the DEM is defined as either bare or debris-covered ice,
and may be covered in snow that must be melted off before ice ablation is assumed
to occur. Each debris-covered pixel is assigned a debris thickness value using
probability distributions based on over 1000 manual thickness measurements. Locally
observed meteorological data are used to run energy balance calculations in every
pixel, using an approach suitable for snow, bare ice or debris-covered ice as
appropriate. The use of the debris model significantly reduces the total ablation
in the debris-covered areas, however the precise reduction is sensitive to the
temperature extrapolation used in the model distribution because air near the
debris surface tends to be slightly warmer than over bare ice. Overall results
suggest that the debris patches, which cover 10% of the glacierized area, reduce
total runoff from the glacierized part of the basin by up to 7%.
article_number: D18105
article_processing_charge: No
article_type: original
author:
- first_name: T. D.
full_name: Reid, T. D.
last_name: Reid
- first_name: M.
full_name: Carenzo, M.
last_name: Carenzo
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: B. W.
full_name: Brock, B. W.
last_name: Brock
citation:
ama: 'Reid TD, Carenzo M, Pellicciotti F, Brock BW. Including debris cover effects
in a distributed model of glacier ablation. Journal of Geophysical Research:
Atmospheres. 2012;117(D18). doi:10.1029/2012jd017795'
apa: 'Reid, T. D., Carenzo, M., Pellicciotti, F., & Brock, B. W. (2012). Including
debris cover effects in a distributed model of glacier ablation. Journal of
Geophysical Research: Atmospheres. American Geophysical Union. https://doi.org/10.1029/2012jd017795'
chicago: 'Reid, T. D., M. Carenzo, Francesca Pellicciotti, and B. W. Brock. “Including
Debris Cover Effects in a Distributed Model of Glacier Ablation.” Journal of
Geophysical Research: Atmospheres. American Geophysical Union, 2012. https://doi.org/10.1029/2012jd017795.'
ieee: 'T. D. Reid, M. Carenzo, F. Pellicciotti, and B. W. Brock, “Including debris
cover effects in a distributed model of glacier ablation,” Journal of Geophysical
Research: Atmospheres, vol. 117, no. D18. American Geophysical Union, 2012.'
ista: 'Reid TD, Carenzo M, Pellicciotti F, Brock BW. 2012. Including debris cover
effects in a distributed model of glacier ablation. Journal of Geophysical Research:
Atmospheres. 117(D18), D18105.'
mla: 'Reid, T. D., et al. “Including Debris Cover Effects in a Distributed Model
of Glacier Ablation.” Journal of Geophysical Research: Atmospheres, vol.
117, no. D18, D18105, American Geophysical Union, 2012, doi:10.1029/2012jd017795.'
short: 'T.D. Reid, M. Carenzo, F. Pellicciotti, B.W. Brock, Journal of Geophysical
Research: Atmospheres 117 (2012).'
date_created: 2023-02-20T08:17:57Z
date_published: 2012-09-27T00:00:00Z
date_updated: 2023-02-20T10:57:31Z
day: '27'
doi: 10.1029/2012jd017795
extern: '1'
intvolume: ' 117'
issue: D18
keyword:
- Paleontology
- Space and Planetary Science
- Earth and Planetary Sciences (miscellaneous)
- Atmospheric Science
- Earth-Surface Processes
- Geochemistry and Petrology
- Soil Science
- Water Science and Technology
- Ecology
- Aquatic Science
- Forestry
- Oceanography
- Geophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1029/2012JD017795
month: '09'
oa: 1
oa_version: Published Version
publication: 'Journal of Geophysical Research: Atmospheres'
publication_identifier:
issn:
- 0148-0227
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: Including debris cover effects in a distributed model of glacier ablation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 117
year: '2012'
...
---
_id: '12651'
abstract:
- lang: eng
text: Temperature data from three Automatic Weather Stations and twelve Temperature
Loggers are used to investigate the spatiotemporal variability of temperature
over a glacier, its main atmospheric controls, the suitability of extrapolation
techniques and their effect on melt modeling. We use data collected on Juncal
Norte Glacier, central Chile, during one ablation season. We examine temporal
and spatial variability in lapse rates (LRs), together with alternative statistical
interpolation methods. The main control over the glacier thermal regime is the
development of a katabatic boundary layer (KBL). Katabatic wind occurs at night
and in the morning and is eroded in the afternoon. LRs reveal strong diurnal variability,
with steeper LRs during the day when the katabatic wind weakens and shallower
LRs during the night and morning. We suggest that temporally variable LRs should
be used to account for the observed change. They tend to be steeper than equivalent
constant LRs, and therefore result in a reduction in simulated melt compared to
use of constant LRs when extrapolating from lower to higher elevations. In addition
to the temporal variability, the temperature-elevation relationship varies also
in space. Differences are evident between local LRs and including such variability
in melt modeling affects melt simulations. Extrapolation methods based on the
spatial variability of the observations after removal of the elevation trend,
such as Inverse Distance Weighting or Kriging, do not seem necessary for simulations
of gridded temperature data over a glacier.
article_number: D23109
article_processing_charge: No
article_type: original
author:
- first_name: L.
full_name: Petersen, L.
last_name: Petersen
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: 'Petersen L, Pellicciotti F. Spatial and temporal variability of air temperature
on a melting glacier: Atmospheric controls, extrapolation methods and their effect
on melt modeling, Juncal Norte Glacier, Chile. Journal of Geophysical Research:
Atmospheres. 2011;116(D23). doi:10.1029/2011jd015842'
apa: 'Petersen, L., & Pellicciotti, F. (2011). Spatial and temporal variability
of air temperature on a melting glacier: Atmospheric controls, extrapolation methods
and their effect on melt modeling, Juncal Norte Glacier, Chile. Journal of
Geophysical Research: Atmospheres. American Geophysical Union. https://doi.org/10.1029/2011jd015842'
chicago: 'Petersen, L., and Francesca Pellicciotti. “Spatial and Temporal Variability
of Air Temperature on a Melting Glacier: Atmospheric Controls, Extrapolation Methods
and Their Effect on Melt Modeling, Juncal Norte Glacier, Chile.” Journal of
Geophysical Research: Atmospheres. American Geophysical Union, 2011. https://doi.org/10.1029/2011jd015842.'
ieee: 'L. Petersen and F. Pellicciotti, “Spatial and temporal variability of air
temperature on a melting glacier: Atmospheric controls, extrapolation methods
and their effect on melt modeling, Juncal Norte Glacier, Chile,” Journal of
Geophysical Research: Atmospheres, vol. 116, no. D23. American Geophysical
Union, 2011.'
ista: 'Petersen L, Pellicciotti F. 2011. Spatial and temporal variability of air
temperature on a melting glacier: Atmospheric controls, extrapolation methods
and their effect on melt modeling, Juncal Norte Glacier, Chile. Journal of Geophysical
Research: Atmospheres. 116(D23), D23109.'
mla: 'Petersen, L., and Francesca Pellicciotti. “Spatial and Temporal Variability
of Air Temperature on a Melting Glacier: Atmospheric Controls, Extrapolation Methods
and Their Effect on Melt Modeling, Juncal Norte Glacier, Chile.” Journal of
Geophysical Research: Atmospheres, vol. 116, no. D23, D23109, American Geophysical
Union, 2011, doi:10.1029/2011jd015842.'
short: 'L. Petersen, F. Pellicciotti, Journal of Geophysical Research: Atmospheres
116 (2011).'
date_created: 2023-02-20T08:18:14Z
date_published: 2011-12-16T00:00:00Z
date_updated: 2023-02-20T10:29:44Z
day: '16'
doi: 10.1029/2011jd015842
extern: '1'
intvolume: ' 116'
issue: D23
keyword:
- Paleontology
- Space and Planetary Science
- Earth and Planetary Sciences (miscellaneous)
- Atmospheric Science
- Earth-Surface Processes
- Geochemistry and Petrology
- Soil Science
- Water Science and Technology
- Ecology
- Aquatic Science
- Forestry
- Oceanography
- Geophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1029/2011JD01584
month: '12'
oa: 1
oa_version: Published Version
publication: 'Journal of Geophysical Research: Atmospheres'
publication_identifier:
issn:
- 0148-0227
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Spatial and temporal variability of air temperature on a melting glacier:
Atmospheric controls, extrapolation methods and their effect on melt modeling, Juncal
Norte Glacier, Chile'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 116
year: '2011'
...
---
_id: '12658'
abstract:
- lang: eng
text: '[1] During the ablation period 2001 a glaciometeorological experiment was
carried out on Haut Glacier d''Arolla, Switzerland. Five meteorological stations
were installed on the glacier, and one permanent automatic weather station in
the glacier foreland. The altitudes of the stations ranged between 2500 and 3000
m a.s.l., and they were in operation from end of May to beginning of September
2001. The spatial arrangement of the stations and temporal duration of the measurements
generated a unique data set enabling the analysis of the spatial and temporal
variability of the meteorological variables across an alpine glacier. All measurements
were taken at a nominal height of 2 m, and hourly averages were derived for the
analysis. The wind regime was dominated by the glacier wind (mean value 2.8 m
s−1) but due to erosion by the synoptic gradient wind, occasionally the wind would
blow up the valley. A slight decrease in mean 2 m air temperatures with altitude
was found, however the 2 m air temperature gradient varied greatly and frequently
changed its sign. Mean relative humidity was 71% and exhibited limited spatial
variation. Mean incoming shortwave radiation and albedo both generally increased
with elevation. The different components of shortwave radiation are quantified
with a parameterization scheme. Resulting spatial variations are mainly due to
horizon obstruction and reflections from surrounding slopes, i.e., topography.
The effect of clouds accounts for a loss of 30% of the extraterrestrial flux.
Albedos derived from a Landsat TM image of 30 July show remarkably constant values,
in the range 0.49 to 0.50, across snow covered parts of the glacier, while albedo
is highly spatially variable below the zone of continuous snow cover. These results
are verified with ground measurements and compared with parameterized albedo.
Mean longwave radiative fluxes decreased with elevation due to lower air temperatures
and the effect of upper hemisphere slopes. It is shown through parameterization
that this effect would even be more pronounced without the effect of clouds. Results
are discussed with respect to a similar study which has been carried out on Pasterze
Glacier (Austria). The presented algorithms for interpolating, parameterizing
and simulating variables and parameters in alpine regions are integrated in the
software package AMUNDSEN which is freely available to be adapted and further
developed by the community.'
article_number: D03103
article_processing_charge: No
article_type: original
author:
- first_name: Ulrich
full_name: Strasser, Ulrich
last_name: Strasser
- first_name: Javier
full_name: Corripio, Javier
last_name: Corripio
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Paolo
full_name: Burlando, Paolo
last_name: Burlando
- first_name: Ben
full_name: Brock, Ben
last_name: Brock
- first_name: Martin
full_name: Funk, Martin
last_name: Funk
citation:
ama: 'Strasser U, Corripio J, Pellicciotti F, Burlando P, Brock B, Funk M. Spatial
and temporal variability of meteorological variables at Haut Glacier d’Arolla
(Switzerland) during the ablation season 2001: Measurements and simulations. Journal
of Geophysical Research: Atmospheres. 2004;109(D3). doi:10.1029/2003jd003973'
apa: 'Strasser, U., Corripio, J., Pellicciotti, F., Burlando, P., Brock, B., &
Funk, M. (2004). Spatial and temporal variability of meteorological variables
at Haut Glacier d’Arolla (Switzerland) during the ablation season 2001: Measurements
and simulations. Journal of Geophysical Research: Atmospheres. American
Geophysical Union. https://doi.org/10.1029/2003jd003973'
chicago: 'Strasser, Ulrich, Javier Corripio, Francesca Pellicciotti, Paolo Burlando,
Ben Brock, and Martin Funk. “Spatial and Temporal Variability of Meteorological
Variables at Haut Glacier d’Arolla (Switzerland) during the Ablation Season 2001:
Measurements and Simulations.” Journal of Geophysical Research: Atmospheres.
American Geophysical Union, 2004. https://doi.org/10.1029/2003jd003973.'
ieee: 'U. Strasser, J. Corripio, F. Pellicciotti, P. Burlando, B. Brock, and M.
Funk, “Spatial and temporal variability of meteorological variables at Haut Glacier
d’Arolla (Switzerland) during the ablation season 2001: Measurements and simulations,”
Journal of Geophysical Research: Atmospheres, vol. 109, no. D3. American
Geophysical Union, 2004.'
ista: 'Strasser U, Corripio J, Pellicciotti F, Burlando P, Brock B, Funk M. 2004.
Spatial and temporal variability of meteorological variables at Haut Glacier d’Arolla
(Switzerland) during the ablation season 2001: Measurements and simulations. Journal
of Geophysical Research: Atmospheres. 109(D3), D03103.'
mla: 'Strasser, Ulrich, et al. “Spatial and Temporal Variability of Meteorological
Variables at Haut Glacier d’Arolla (Switzerland) during the Ablation Season 2001:
Measurements and Simulations.” Journal of Geophysical Research: Atmospheres,
vol. 109, no. D3, D03103, American Geophysical Union, 2004, doi:10.1029/2003jd003973.'
short: 'U. Strasser, J. Corripio, F. Pellicciotti, P. Burlando, B. Brock, M. Funk,
Journal of Geophysical Research: Atmospheres 109 (2004).'
date_created: 2023-02-20T08:18:57Z
date_published: 2004-02-16T00:00:00Z
date_updated: 2023-02-20T08:40:21Z
day: '16'
doi: 10.1029/2003jd003973
extern: '1'
intvolume: ' 109'
issue: D3
keyword:
- Paleontology
- Space and Planetary Science
- Earth and Planetary Sciences (miscellaneous)
- Atmospheric Science
- Earth-Surface Processes
- Geochemistry and Petrology
- Soil Science
- Water Science and Technology
- Ecology
- Aquatic Science
- Forestry
- Oceanography
- Geophysics
language:
- iso: eng
month: '02'
oa_version: None
publication: 'Journal of Geophysical Research: Atmospheres'
publication_identifier:
issn:
- 0148-0227
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Spatial and temporal variability of meteorological variables at Haut Glacier
d''Arolla (Switzerland) during the ablation season 2001: Measurements and simulations'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 109
year: '2004'
...