---
_id: '10015'
abstract:
- lang: eng
  text: "Auxin plays a dual role in growth regulation and, depending on the tissue
    and concentration of the hormone, it can either promote or inhibit division and
    expansion processes in plants. Recent studies have revealed that, beyond transcriptional
    reprogramming, alternative auxincontrolled mechanisms regulate root growth. Here,
    we explored the impact of different concentrations of the synthetic auxin NAA
    that establish growth-promoting and -repressing conditions on the root tip proteome
    and phosphoproteome, generating a unique resource. From the phosphoproteome data,
    we pinpointed (novel) growth regulators, such as the RALF34-THE1 module. Our results,
    together with previously published studies, suggest that auxin, H+-ATPases, cell
    wall modifications and cell wall sensing receptor-like kinases are tightly embedded
    in a pathway regulating cell elongation. Furthermore, our study assigned a novel
    role to MKK2 as a regulator of primary root growth and a (potential) regulator
    of auxin biosynthesis and signalling, and suggests the importance of the MKK2\r\nThr31
    phosphorylation site for growth regulation in the Arabidopsis root tip."
acknowledgement: We thank the Nottingham Stock Centre for seeds, Frank Van Breusegem
  for the phb3 mutant, and Herman Höfte for the the1 mutant. Open Access Funding by
  the Austrian Science Fund (FWF).
alternative_title:
- Protein Phosphorylation and Cell Signaling in Plants
article_number: '1665 '
article_processing_charge: Yes
article_type: original
author:
- first_name: N
  full_name: Nikonorova, N
  last_name: Nikonorova
- first_name: E
  full_name: Murphy, E
  last_name: Murphy
- first_name: CF
  full_name: Fonseca de Lima, CF
  last_name: Fonseca de Lima
- first_name: S
  full_name: Zhu, S
  last_name: Zhu
- first_name: B
  full_name: van de Cotte, B
  last_name: van de Cotte
- first_name: LD
  full_name: Vu, LD
  last_name: Vu
- first_name: D
  full_name: Balcerowicz, D
  last_name: Balcerowicz
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: X
  full_name: Kong, X
  last_name: Kong
- first_name: G
  full_name: De Rop, G
  last_name: De Rop
- first_name: T
  full_name: Beeckman, T
  last_name: Beeckman
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: K
  full_name: Vissenberg, K
  last_name: Vissenberg
- first_name: PC
  full_name: Morris, PC
  last_name: Morris
- first_name: Z
  full_name: Ding, Z
  last_name: Ding
- first_name: I
  full_name: De Smet, I
  last_name: De Smet
citation:
  ama: Nikonorova N, Murphy E, Fonseca de Lima C, et al. The Arabidopsis root tip
    (phospho)proteomes at growth-promoting versus growth-repressing conditions reveal
    novel root growth regulators. <i>Cells</i>. 2021;10. doi:<a href="https://doi.org/10.3390/cells10071665">10.3390/cells10071665</a>
  apa: Nikonorova, N., Murphy, E., Fonseca de Lima, C., Zhu, S., van de Cotte, B.,
    Vu, L., … De Smet, I. (2021). The Arabidopsis root tip (phospho)proteomes at growth-promoting
    versus growth-repressing conditions reveal novel root growth regulators. <i>Cells</i>.
    MDPI. <a href="https://doi.org/10.3390/cells10071665">https://doi.org/10.3390/cells10071665</a>
  chicago: Nikonorova, N, E Murphy, CF Fonseca de Lima, S Zhu, B van de Cotte, LD
    Vu, D Balcerowicz, et al. “The Arabidopsis Root Tip (Phospho)Proteomes at Growth-Promoting
    versus Growth-Repressing Conditions Reveal Novel Root Growth Regulators.” <i>Cells</i>.
    MDPI, 2021. <a href="https://doi.org/10.3390/cells10071665">https://doi.org/10.3390/cells10071665</a>.
  ieee: N. Nikonorova <i>et al.</i>, “The Arabidopsis root tip (phospho)proteomes
    at growth-promoting versus growth-repressing conditions reveal novel root growth
    regulators,” <i>Cells</i>, vol. 10. MDPI, 2021.
  ista: Nikonorova N, Murphy E, Fonseca de Lima C, Zhu S, van de Cotte B, Vu L, Balcerowicz
    D, Li L, Kong X, De Rop G, Beeckman T, Friml J, Vissenberg K, Morris P, Ding Z,
    De Smet I. 2021. The Arabidopsis root tip (phospho)proteomes at growth-promoting
    versus growth-repressing conditions reveal novel root growth regulators. Cells.
    10, 1665.
  mla: Nikonorova, N., et al. “The Arabidopsis Root Tip (Phospho)Proteomes at Growth-Promoting
    versus Growth-Repressing Conditions Reveal Novel Root Growth Regulators.” <i>Cells</i>,
    vol. 10, 1665, MDPI, 2021, doi:<a href="https://doi.org/10.3390/cells10071665">10.3390/cells10071665</a>.
  short: N. Nikonorova, E. Murphy, C. Fonseca de Lima, S. Zhu, B. van de Cotte, L.
    Vu, D. Balcerowicz, L. Li, X. Kong, G. De Rop, T. Beeckman, J. Friml, K. Vissenberg,
    P. Morris, Z. Ding, I. De Smet, Cells 10 (2021).
date_created: 2021-09-14T11:36:20Z
date_published: 2021-07-02T00:00:00Z
date_updated: 2024-10-29T10:22:44Z
day: '02'
ddc:
- '575'
department:
- _id: JiFr
doi: 10.3390/cells10071665
ec_funded: 1
external_id:
  isi:
  - '000676604700001'
  pmid:
  - '34359847'
file:
- access_level: open_access
  checksum: 2a9f534b9c2200e72e2cde95afaf4eed
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-09-16T09:07:06Z
  date_updated: 2021-09-16T09:07:06Z
  file_id: '10021'
  file_name: 2021_Cells_Nikonorova.pdf
  file_size: 2667848
  relation: main_file
  success: 1
file_date_updated: 2021-09-16T09:07:06Z
has_accepted_license: '1'
intvolume: '        10'
isi: 1
keyword:
- primary root
- (phospho)proteomics
- auxin
- (receptor) kinase
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
publication: Cells
publication_identifier:
  issn:
  - 2073-4409
publication_status: published
publisher: MDPI
quality_controlled: '1'
related_material:
  record:
  - id: '10083'
    relation: dissertation_contains
    status: public
status: public
title: The Arabidopsis root tip (phospho)proteomes at growth-promoting versus growth-repressing
  conditions reveal novel root growth regulators
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2021'
...
---
_id: '12200'
abstract:
- lang: eng
  text: Key steps in the evolution of the angiosperm anther include the patterning
    of the concentrically organized microsporangium and the incorporation of four
    such microsporangia into a leaf-like structure. Mutant studies in the model plant
    Arabidopsis thaliana are leading to an increasingly accurate picture of (i) the
    cell lineages culminating in the different cell types present in the microsporangium
    (the microsporocytes, the tapetum, and the middle and endothecial layers), and
    (ii) some of the genes responsible for specifying their fates. However, the processes
    that confer polarity on the developing anther and position the microsporangia
    within it remain unclear. Certainly, data from a range of experimental strategies
    suggest that hormones play a central role in establishing polarity and the patterning
    of the anther initial, and may be responsible for locating the microsporangia.
    But the fact that microsporangia were originally positioned externally suggests
    that their development is likely to be autonomous, perhaps with the reproductive
    cells generating signals controlling the growth and division of the investing
    anther epidermis. These possibilities are discussed in the context of the expression
    of genes which initiate and maintain male and female reproductive development,
    and in the perspective of our current views of anther evolution.
article_processing_charge: No
article_type: original
author:
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
- first_name: Hugh G.
  full_name: Dickinson, Hugh G.
  last_name: Dickinson
citation:
  ama: Feng X, Dickinson HG. Cell–cell interactions during patterning of the <i>Arabidopsis</i>
    anther. <i>Biochemical Society Transactions</i>. 2010;38(2):571-576. doi:<a href="https://doi.org/10.1042/bst0380571">10.1042/bst0380571</a>
  apa: Feng, X., &#38; Dickinson, H. G. (2010). Cell–cell interactions during patterning
    of the <i>Arabidopsis</i> anther. <i>Biochemical Society Transactions</i>. Portland
    Press Ltd. <a href="https://doi.org/10.1042/bst0380571">https://doi.org/10.1042/bst0380571</a>
  chicago: Feng, Xiaoqi, and Hugh G. Dickinson. “Cell–Cell Interactions during Patterning
    of the <i>Arabidopsis</i> Anther.” <i>Biochemical Society Transactions</i>. Portland
    Press Ltd., 2010. <a href="https://doi.org/10.1042/bst0380571">https://doi.org/10.1042/bst0380571</a>.
  ieee: X. Feng and H. G. Dickinson, “Cell–cell interactions during patterning of
    the <i>Arabidopsis</i> anther,” <i>Biochemical Society Transactions</i>, vol.
    38, no. 2. Portland Press Ltd., pp. 571–576, 2010.
  ista: Feng X, Dickinson HG. 2010. Cell–cell interactions during patterning of the
    <i>Arabidopsis</i> anther. Biochemical Society Transactions. 38(2), 571–576.
  mla: Feng, Xiaoqi, and Hugh G. Dickinson. “Cell–Cell Interactions during Patterning
    of the <i>Arabidopsis</i> Anther.” <i>Biochemical Society Transactions</i>, vol.
    38, no. 2, Portland Press Ltd., 2010, pp. 571–76, doi:<a href="https://doi.org/10.1042/bst0380571">10.1042/bst0380571</a>.
  short: X. Feng, H.G. Dickinson, Biochemical Society Transactions 38 (2010) 571–576.
date_created: 2023-01-16T09:22:18Z
date_published: 2010-03-22T00:00:00Z
date_updated: 2023-05-08T10:57:59Z
day: '22'
department:
- _id: XiFe
doi: 10.1042/bst0380571
extern: '1'
external_id:
  pmid:
  - '20298223'
intvolume: '        38'
issue: '2'
keyword:
- Biochemistry
- Anther Development
- Arabidopsis
- Cell Fate
- Microsporangium
- Polarity
- Receptor Kinase
language:
- iso: eng
month: '03'
oa_version: None
page: 571-576
pmid: 1
publication: Biochemical Society Transactions
publication_identifier:
  issn:
  - 0300-5127
  - 1470-8752
publication_status: published
publisher: Portland Press Ltd.
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell–cell interactions during patterning of the <i>Arabidopsis</i> anther
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 38
year: '2010'
...