---
_id: '7069'
abstract:
- lang: eng
text: The observation of a reconstructed Fermi surface via quantum oscillations
in hole-doped cuprates opened a path towards identifying broken symmetry states
in the pseudogap regime. However, such an identification has remained inconclusive
due to the multi-frequency quantum oscillation spectra and complications accounting
for bilayer effects in most studies. We overcome these impediments with high-resolution
measurements on the structurally simpler cuprate HgBa2CuO4+δ (Hg1201), which features
one CuO2 plane per primitive unit cell. We find only a single oscillatory component
with no signatures of magnetic breakdown tunnelling to additional orbits. Therefore,
the Fermi surface comprises a single quasi-two-dimensional pocket. Quantitative
modelling of these results indicates that a biaxial charge density wave within
each CuO2 plane is responsible for the reconstruction and rules out criss-crossed
charge stripes between layers as a viable alternative in Hg1201. Lastly, we determine
that the characteristic gap between reconstructed pockets is a significant fraction
of the pseudogap energy.
article_number: '12244'
article_processing_charge: No
article_type: original
author:
- first_name: M. K.
full_name: Chan, M. K.
last_name: Chan
- first_name: N.
full_name: Harrison, N.
last_name: Harrison
- first_name: R. D.
full_name: McDonald, R. D.
last_name: McDonald
- first_name: B. J.
full_name: Ramshaw, B. J.
last_name: Ramshaw
- first_name: Kimberly A
full_name: Modic, Kimberly A
id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
last_name: Modic
orcid: 0000-0001-9760-3147
- first_name: N.
full_name: Barišić, N.
last_name: Barišić
- first_name: M.
full_name: Greven, M.
last_name: Greven
citation:
ama: Chan MK, Harrison N, McDonald RD, et al. Single reconstructed Fermi surface
pocket in an underdoped single-layer cuprate superconductor. Nature Communications.
2016;7. doi:10.1038/ncomms12244
apa: Chan, M. K., Harrison, N., McDonald, R. D., Ramshaw, B. J., Modic, K. A., Barišić,
N., & Greven, M. (2016). Single reconstructed Fermi surface pocket in an underdoped
single-layer cuprate superconductor. Nature Communications. Springer Nature.
https://doi.org/10.1038/ncomms12244
chicago: Chan, M. K., N. Harrison, R. D. McDonald, B. J. Ramshaw, Kimberly A Modic,
N. Barišić, and M. Greven. “Single Reconstructed Fermi Surface Pocket in an Underdoped
Single-Layer Cuprate Superconductor.” Nature Communications. Springer Nature,
2016. https://doi.org/10.1038/ncomms12244.
ieee: M. K. Chan et al., “Single reconstructed Fermi surface pocket in an
underdoped single-layer cuprate superconductor,” Nature Communications,
vol. 7. Springer Nature, 2016.
ista: Chan MK, Harrison N, McDonald RD, Ramshaw BJ, Modic KA, Barišić N, Greven
M. 2016. Single reconstructed Fermi surface pocket in an underdoped single-layer
cuprate superconductor. Nature Communications. 7, 12244.
mla: Chan, M. K., et al. “Single Reconstructed Fermi Surface Pocket in an Underdoped
Single-Layer Cuprate Superconductor.” Nature Communications, vol. 7, 12244,
Springer Nature, 2016, doi:10.1038/ncomms12244.
short: M.K. Chan, N. Harrison, R.D. McDonald, B.J. Ramshaw, K.A. Modic, N. Barišić,
M. Greven, Nature Communications 7 (2016).
date_created: 2019-11-19T13:21:23Z
date_published: 2016-07-22T00:00:00Z
date_updated: 2021-01-12T08:11:41Z
day: '22'
doi: 10.1038/ncomms12244
extern: '1'
intvolume: ' 7'
language:
- iso: eng
month: '07'
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Single reconstructed Fermi surface pocket in an underdoped single-layer cuprate
superconductor
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...
---
_id: '8456'
abstract:
- lang: eng
text: The large majority of three-dimensional structures of biological macromolecules
have been determined by X-ray diffraction of crystalline samples. High-resolution
structure determination crucially depends on the homogeneity of the protein crystal.
Overall ‘rocking’ motion of molecules in the crystal is expected to influence
diffraction quality, and such motion may therefore affect the process of solving
crystal structures. Yet, so far overall molecular motion has not directly been
observed in protein crystals, and the timescale of such dynamics remains unclear.
Here we use solid-state NMR, X-ray diffraction methods and μs-long molecular dynamics
simulations to directly characterize the rigid-body motion of a protein in different
crystal forms. For ubiquitin crystals investigated in this study we determine
the range of possible correlation times of rocking motion, 0.1–100 μs. The amplitude
of rocking varies from one crystal form to another and is correlated with the
resolution obtainable in X-ray diffraction experiments.
article_number: '8361'
article_processing_charge: No
article_type: original
author:
- first_name: Peixiang
full_name: Ma, Peixiang
last_name: Ma
- first_name: Yi
full_name: Xue, Yi
last_name: Xue
- first_name: Nicolas
full_name: Coquelle, Nicolas
last_name: Coquelle
- first_name: Jens D.
full_name: Haller, Jens D.
last_name: Haller
- first_name: Tairan
full_name: Yuwen, Tairan
last_name: Yuwen
- first_name: Isabel
full_name: Ayala, Isabel
last_name: Ayala
- first_name: Oleg
full_name: Mikhailovskii, Oleg
last_name: Mikhailovskii
- first_name: Dieter
full_name: Willbold, Dieter
last_name: Willbold
- first_name: Jacques-Philippe
full_name: Colletier, Jacques-Philippe
last_name: Colletier
- first_name: Nikolai R.
full_name: Skrynnikov, Nikolai R.
last_name: Skrynnikov
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
citation:
ama: Ma P, Xue Y, Coquelle N, et al. Observing the overall rocking motion of a protein
in a crystal. Nature Communications. 2015;6. doi:10.1038/ncomms9361
apa: Ma, P., Xue, Y., Coquelle, N., Haller, J. D., Yuwen, T., Ayala, I., … Schanda,
P. (2015). Observing the overall rocking motion of a protein in a crystal. Nature
Communications. Springer Nature. https://doi.org/10.1038/ncomms9361
chicago: Ma, Peixiang, Yi Xue, Nicolas Coquelle, Jens D. Haller, Tairan Yuwen, Isabel
Ayala, Oleg Mikhailovskii, et al. “Observing the Overall Rocking Motion of a Protein
in a Crystal.” Nature Communications. Springer Nature, 2015. https://doi.org/10.1038/ncomms9361.
ieee: P. Ma et al., “Observing the overall rocking motion of a protein in
a crystal,” Nature Communications, vol. 6. Springer Nature, 2015.
ista: Ma P, Xue Y, Coquelle N, Haller JD, Yuwen T, Ayala I, Mikhailovskii O, Willbold
D, Colletier J-P, Skrynnikov NR, Schanda P. 2015. Observing the overall rocking
motion of a protein in a crystal. Nature Communications. 6, 8361.
mla: Ma, Peixiang, et al. “Observing the Overall Rocking Motion of a Protein in
a Crystal.” Nature Communications, vol. 6, 8361, Springer Nature, 2015,
doi:10.1038/ncomms9361.
short: P. Ma, Y. Xue, N. Coquelle, J.D. Haller, T. Yuwen, I. Ayala, O. Mikhailovskii,
D. Willbold, J.-P. Colletier, N.R. Skrynnikov, P. Schanda, Nature Communications
6 (2015).
date_created: 2020-09-18T10:07:36Z
date_published: 2015-10-05T00:00:00Z
date_updated: 2021-01-12T08:19:24Z
day: '05'
doi: 10.1038/ncomms9361
extern: '1'
intvolume: ' 6'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
month: '10'
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Observing the overall rocking motion of a protein in a crystal
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '7071'
abstract:
- lang: eng
text: Spin and orbital quantum numbers play a key role in the physics of Mott insulators,
but in most systems they are connected only indirectly—via the Pauli exclusion
principle and the Coulomb interaction. Iridium-based oxides (iridates) introduce
strong spin–orbit coupling directly, such that these numbers become entwined together
and the Mott physics attains a strong orbital character. In the layered honeycomb
iridates this is thought to generate highly spin–anisotropic magnetic interactions,
coupling the spin to a given spatial direction of exchange and leading to strongly
frustrated magnetism. Here we report a new iridate structure that has the same
local connectivity as the layered honeycomb and exhibits striking evidence for
highly spin–anisotropic exchange. The basic structural units of this material
suggest that a new family of three-dimensional structures could exist, the ‘harmonic
honeycomb’ iridates, of which the present compound is the first example.
article_number: '4203'
article_processing_charge: No
article_type: original
author:
- first_name: Kimberly A
full_name: Modic, Kimberly A
id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
last_name: Modic
orcid: 0000-0001-9760-3147
- first_name: Tess E.
full_name: Smidt, Tess E.
last_name: Smidt
- first_name: Itamar
full_name: Kimchi, Itamar
last_name: Kimchi
- first_name: Nicholas P.
full_name: Breznay, Nicholas P.
last_name: Breznay
- first_name: Alun
full_name: Biffin, Alun
last_name: Biffin
- first_name: Sungkyun
full_name: Choi, Sungkyun
last_name: Choi
- first_name: Roger D.
full_name: Johnson, Roger D.
last_name: Johnson
- first_name: Radu
full_name: Coldea, Radu
last_name: Coldea
- first_name: Pilanda
full_name: Watkins-Curry, Pilanda
last_name: Watkins-Curry
- first_name: Gregory T.
full_name: McCandless, Gregory T.
last_name: McCandless
- first_name: Julia Y.
full_name: Chan, Julia Y.
last_name: Chan
- first_name: Felipe
full_name: Gandara, Felipe
last_name: Gandara
- first_name: Z.
full_name: Islam, Z.
last_name: Islam
- first_name: Ashvin
full_name: Vishwanath, Ashvin
last_name: Vishwanath
- first_name: Arkady
full_name: Shekhter, Arkady
last_name: Shekhter
- first_name: Ross D.
full_name: McDonald, Ross D.
last_name: McDonald
- first_name: James G.
full_name: Analytis, James G.
last_name: Analytis
citation:
ama: Modic KA, Smidt TE, Kimchi I, et al. Realization of a three-dimensional spin–anisotropic
harmonic honeycomb iridate. Nature Communications. 2014;5. doi:10.1038/ncomms5203
apa: Modic, K. A., Smidt, T. E., Kimchi, I., Breznay, N. P., Biffin, A., Choi, S.,
… Analytis, J. G. (2014). Realization of a three-dimensional spin–anisotropic
harmonic honeycomb iridate. Nature Communications. Springer Science and
Business Media LLC. https://doi.org/10.1038/ncomms5203
chicago: Modic, Kimberly A, Tess E. Smidt, Itamar Kimchi, Nicholas P. Breznay, Alun
Biffin, Sungkyun Choi, Roger D. Johnson, et al. “Realization of a Three-Dimensional
Spin–Anisotropic Harmonic Honeycomb Iridate.” Nature Communications. Springer
Science and Business Media LLC, 2014. https://doi.org/10.1038/ncomms5203.
ieee: K. A. Modic et al., “Realization of a three-dimensional spin–anisotropic
harmonic honeycomb iridate,” Nature Communications, vol. 5. Springer Science
and Business Media LLC, 2014.
ista: Modic KA, Smidt TE, Kimchi I, Breznay NP, Biffin A, Choi S, Johnson RD, Coldea
R, Watkins-Curry P, McCandless GT, Chan JY, Gandara F, Islam Z, Vishwanath A,
Shekhter A, McDonald RD, Analytis JG. 2014. Realization of a three-dimensional
spin–anisotropic harmonic honeycomb iridate. Nature Communications. 5, 4203.
mla: Modic, Kimberly A., et al. “Realization of a Three-Dimensional Spin–Anisotropic
Harmonic Honeycomb Iridate.” Nature Communications, vol. 5, 4203, Springer
Science and Business Media LLC, 2014, doi:10.1038/ncomms5203.
short: K.A. Modic, T.E. Smidt, I. Kimchi, N.P. Breznay, A. Biffin, S. Choi, R.D.
Johnson, R. Coldea, P. Watkins-Curry, G.T. McCandless, J.Y. Chan, F. Gandara,
Z. Islam, A. Vishwanath, A. Shekhter, R.D. McDonald, J.G. Analytis, Nature Communications
5 (2014).
date_created: 2019-11-19T13:22:39Z
date_published: 2014-06-27T00:00:00Z
date_updated: 2021-01-12T08:11:42Z
day: '27'
ddc:
- '530'
doi: 10.1038/ncomms5203
extern: '1'
file:
- access_level: open_access
checksum: d290f0bfa93c5169cc6c8086874c5a78
content_type: application/pdf
creator: dernst
date_created: 2019-11-26T12:44:23Z
date_updated: 2020-07-14T12:47:48Z
file_id: '7113'
file_name: 2014_NatureComm_Modic.pdf
file_size: 4832820
relation: main_file
file_date_updated: 2020-07-14T12:47:48Z
has_accepted_license: '1'
intvolume: ' 5'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Science and Business Media LLC
quality_controlled: '1'
status: public
title: Realization of a three-dimensional spin–anisotropic harmonic honeycomb iridate
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2014'
...
---
_id: '7361'
abstract:
- lang: eng
text: Bistable switches are fundamental regulatory elements of complex systems,
ranging from electronics to living cells. Designed genetic toggle switches have
been constructed from pairs of natural transcriptional repressors wired to inhibit
one another. The complexity of the engineered regulatory circuits can be increased
using orthogonal transcriptional regulators based on designed DNA-binding domains.
However, a mutual repressor-based toggle switch comprising DNA-binding domains
of transcription-activator-like effectors (TALEs) did not support bistability
in mammalian cells. Here, the challenge of engineering a bistable switch based
on monomeric DNA-binding domains is solved via the introduction of a positive
feedback loop composed of activators based on the same TALE domains as their opposing
repressors and competition for the same DNA operator site. This design introduces
nonlinearity and results in epigenetic bistability. This principle could be used
to employ other monomeric DNA-binding domains such as CRISPR for applications
ranging from reprogramming cells to building digital biological memory.
article_number: '5007'
article_processing_charge: No
article_type: original
author:
- first_name: Tina
full_name: Lebar, Tina
last_name: Lebar
- first_name: Urban
full_name: Bezeljak, Urban
id: 2A58201A-F248-11E8-B48F-1D18A9856A87
last_name: Bezeljak
orcid: 0000-0003-1365-5631
- first_name: Anja
full_name: Golob, Anja
last_name: Golob
- first_name: Miha
full_name: Jerala, Miha
last_name: Jerala
- first_name: Lucija
full_name: Kadunc, Lucija
last_name: Kadunc
- first_name: Boštjan
full_name: Pirš, Boštjan
last_name: Pirš
- first_name: Martin
full_name: Stražar, Martin
last_name: Stražar
- first_name: Dušan
full_name: Vučko, Dušan
last_name: Vučko
- first_name: Uroš
full_name: Zupančič, Uroš
last_name: Zupančič
- first_name: Mojca
full_name: Benčina, Mojca
last_name: Benčina
- first_name: Vida
full_name: Forstnerič, Vida
last_name: Forstnerič
- first_name: Rok
full_name: Gaber, Rok
last_name: Gaber
- first_name: Jan
full_name: Lonzarić, Jan
last_name: Lonzarić
- first_name: Andreja
full_name: Majerle, Andreja
last_name: Majerle
- first_name: Alja
full_name: Oblak, Alja
last_name: Oblak
- first_name: Anže
full_name: Smole, Anže
last_name: Smole
- first_name: Roman
full_name: Jerala, Roman
last_name: Jerala
citation:
ama: Lebar T, Bezeljak U, Golob A, et al. A bistable genetic switch based on designable
DNA-binding domains. Nature Communications. 2014;5(1). doi:10.1038/ncomms6007
apa: Lebar, T., Bezeljak, U., Golob, A., Jerala, M., Kadunc, L., Pirš, B., … Jerala,
R. (2014). A bistable genetic switch based on designable DNA-binding domains.
Nature Communications. Springer Nature. https://doi.org/10.1038/ncomms6007
chicago: Lebar, Tina, Urban Bezeljak, Anja Golob, Miha Jerala, Lucija Kadunc, Boštjan
Pirš, Martin Stražar, et al. “A Bistable Genetic Switch Based on Designable DNA-Binding
Domains.” Nature Communications. Springer Nature, 2014. https://doi.org/10.1038/ncomms6007.
ieee: T. Lebar et al., “A bistable genetic switch based on designable DNA-binding
domains,” Nature Communications, vol. 5, no. 1. Springer Nature, 2014.
ista: Lebar T, Bezeljak U, Golob A, Jerala M, Kadunc L, Pirš B, Stražar M, Vučko
D, Zupančič U, Benčina M, Forstnerič V, Gaber R, Lonzarić J, Majerle A, Oblak
A, Smole A, Jerala R. 2014. A bistable genetic switch based on designable DNA-binding
domains. Nature Communications. 5(1), 5007.
mla: Lebar, Tina, et al. “A Bistable Genetic Switch Based on Designable DNA-Binding
Domains.” Nature Communications, vol. 5, no. 1, 5007, Springer Nature,
2014, doi:10.1038/ncomms6007.
short: T. Lebar, U. Bezeljak, A. Golob, M. Jerala, L. Kadunc, B. Pirš, M. Stražar,
D. Vučko, U. Zupančič, M. Benčina, V. Forstnerič, R. Gaber, J. Lonzarić, A. Majerle,
A. Oblak, A. Smole, R. Jerala, Nature Communications 5 (2014).
date_created: 2020-01-25T15:57:17Z
date_published: 2014-09-29T00:00:00Z
date_updated: 2021-01-12T08:13:15Z
day: '29'
doi: 10.1038/ncomms6007
extern: '1'
external_id:
pmid:
- '25264186'
intvolume: ' 5'
issue: '1'
language:
- iso: eng
month: '09'
oa_version: None
pmid: 1
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: A bistable genetic switch based on designable DNA-binding domains
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2014'
...