[{"article_type":"original","publisher":"Springer Nature","file_date_updated":"2020-07-14T12:47:53Z","quality_controlled":"1","ec_funded":1,"title":"Cooperative ordering of treadmilling filaments in cytoskeletal networks of FtsZ and its crosslinker ZapA","intvolume":"        10","publication_status":"published","department":[{"_id":"MaLo"},{"_id":"BjHo"}],"article_processing_charge":"No","date_created":"2019-12-20T12:22:57Z","author":[{"first_name":"Paulo R","last_name":"Dos Santos Caldas","orcid":"0000-0001-6730-4461","full_name":"Dos Santos Caldas, Paulo R","id":"38FCDB4C-F248-11E8-B48F-1D18A9856A87"},{"id":"319AA9CE-F248-11E8-B48F-1D18A9856A87","full_name":"Lopez Pelegrin, Maria D","last_name":"Lopez Pelegrin","first_name":"Maria D"},{"full_name":"Pearce, Daniel J. G.","first_name":"Daniel J. G.","last_name":"Pearce"},{"id":"3EA1010E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-0423-5010","full_name":"Budanur, Nazmi B","first_name":"Nazmi B","last_name":"Budanur"},{"full_name":"Brugués, Jan","last_name":"Brugués","first_name":"Jan"},{"id":"462D4284-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7309-9724","full_name":"Loose, Martin","first_name":"Martin","last_name":"Loose"}],"_id":"7197","scopus_import":"1","ddc":["570"],"volume":10,"abstract":[{"lang":"eng","text":"During bacterial cell division, the tubulin-homolog FtsZ forms a ring-like structure at the center of the cell. This Z-ring not only organizes the division machinery, but treadmilling of FtsZ filaments was also found to play a key role in distributing proteins at the division site. What regulates the architecture, dynamics and stability of the Z-ring is currently unknown, but FtsZ-associated proteins are known to play an important role. Here, using an in vitro reconstitution approach, we studied how the well-conserved protein ZapA affects FtsZ treadmilling and filament organization into large-scale patterns. Using high-resolution fluorescence microscopy and quantitative image analysis, we found that ZapA cooperatively increases the spatial order of the filament network, but binds only transiently to FtsZ filaments and has no effect on filament length and treadmilling velocity. Together, our data provides a model for how FtsZ-associated proteins can increase the precision and stability of the bacterial cell division machinery in a switch-like manner."}],"doi":"10.1038/s41467-019-13702-4","day":"17","isi":1,"external_id":{"isi":["000503009300001"]},"date_updated":"2023-09-07T13:18:51Z","year":"2019","citation":{"ista":"Dos Santos Caldas PR, Lopez Pelegrin MD, Pearce DJG, Budanur NB, Brugués J, Loose M. 2019. Cooperative ordering of treadmilling filaments in cytoskeletal networks of FtsZ and its crosslinker ZapA. Nature Communications. 10, 5744.","mla":"Dos Santos Caldas, Paulo R., et al. “Cooperative Ordering of Treadmilling Filaments in Cytoskeletal Networks of FtsZ and Its Crosslinker ZapA.” <i>Nature Communications</i>, vol. 10, 5744, Springer Nature, 2019, doi:<a href=\"https://doi.org/10.1038/s41467-019-13702-4\">10.1038/s41467-019-13702-4</a>.","short":"P.R. Dos Santos Caldas, M.D. Lopez Pelegrin, D.J.G. Pearce, N.B. Budanur, J. Brugués, M. Loose, Nature Communications 10 (2019).","ieee":"P. R. Dos Santos Caldas, M. D. Lopez Pelegrin, D. J. G. Pearce, N. B. Budanur, J. Brugués, and M. Loose, “Cooperative ordering of treadmilling filaments in cytoskeletal networks of FtsZ and its crosslinker ZapA,” <i>Nature Communications</i>, vol. 10. Springer Nature, 2019.","chicago":"Dos Santos Caldas, Paulo R, Maria D Lopez Pelegrin, Daniel J. G. Pearce, Nazmi B Budanur, Jan Brugués, and Martin Loose. “Cooperative Ordering of Treadmilling Filaments in Cytoskeletal Networks of FtsZ and Its Crosslinker ZapA.” <i>Nature Communications</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41467-019-13702-4\">https://doi.org/10.1038/s41467-019-13702-4</a>.","apa":"Dos Santos Caldas, P. R., Lopez Pelegrin, M. D., Pearce, D. J. G., Budanur, N. B., Brugués, J., &#38; Loose, M. (2019). Cooperative ordering of treadmilling filaments in cytoskeletal networks of FtsZ and its crosslinker ZapA. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-019-13702-4\">https://doi.org/10.1038/s41467-019-13702-4</a>","ama":"Dos Santos Caldas PR, Lopez Pelegrin MD, Pearce DJG, Budanur NB, Brugués J, Loose M. Cooperative ordering of treadmilling filaments in cytoskeletal networks of FtsZ and its crosslinker ZapA. <i>Nature Communications</i>. 2019;10. doi:<a href=\"https://doi.org/10.1038/s41467-019-13702-4\">10.1038/s41467-019-13702-4</a>"},"language":[{"iso":"eng"}],"month":"12","article_number":"5744","oa_version":"Published Version","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"project":[{"_id":"2595697A-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"679239","name":"Self-Organization of the Bacterial Cell"},{"name":"Reconstitution of Bacterial Cell Division Using Purified Components","_id":"260D98C8-B435-11E9-9278-68D0E5697425"}],"publication":"Nature Communications","has_accepted_license":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","status":"public","related_material":{"record":[{"status":"public","id":"8358","relation":"dissertation_contains"}]},"file":[{"checksum":"a1b44b427ba341383197790d0e8789fa","file_size":8488733,"date_created":"2019-12-23T07:34:56Z","content_type":"application/pdf","file_name":"2019_NatureComm_Caldas.pdf","date_updated":"2020-07-14T12:47:53Z","access_level":"open_access","relation":"main_file","creator":"dernst","file_id":"7208"}],"oa":1,"publication_identifier":{"issn":["2041-1723"]},"date_published":"2019-12-17T00:00:00Z","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"oa":1,"publication_identifier":{"issn":["2041-1723"]},"type":"journal_article","date_published":"2019-03-26T00:00:00Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","file":[{"date_updated":"2020-07-14T12:47:55Z","content_type":"application/pdf","file_name":"2019_NatureComm_Kwak.pdf","date_created":"2020-01-22T15:58:54Z","checksum":"123dd33e7f26761c82c74e10811a1e4d","file_size":1003676,"file_id":"7355","creator":"dernst","relation":"main_file","access_level":"open_access"}],"article_number":"1380","month":"03","oa_version":"Published Version","has_accepted_license":"1","publication":"Nature Communications","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Non-aqueous lithium-oxygen batteries cycle by forming lithium peroxide during discharge and oxidizing it during recharge. The significant problem of oxidizing the solid insulating lithium peroxide can greatly be facilitated by incorporating redox mediators that shuttle electron-holes between the porous substrate and lithium peroxide. Redox mediator stability is thus key for energy efficiency, reversibility, and cycle life. However, the gradual deactivation of redox mediators during repeated cycling has not conclusively been explained. Here, we show that organic redox mediators are predominantly decomposed by singlet oxygen that forms during cycling. Their reaction with superoxide, previously assumed to mainly trigger their degradation, peroxide, and dioxygen, is orders of magnitude slower in comparison. The reduced form of the mediator is markedly more reactive towards singlet oxygen than the oxidized form, from which we derive reaction mechanisms supported by density functional theory calculations. Redox mediators must thus be designed for stability against singlet oxygen."}],"day":"26","doi":"10.1038/s41467-019-09399-0","year":"2019","citation":{"ista":"Kwak W-J, Kim H, Petit YK, Leypold C, Nguyen TT, Mahne N, Redfern P, Curtiss LA, Jung H-G, Borisov SM, Freunberger SA, Sun Y-K. 2019. Deactivation of redox mediators in lithium-oxygen batteries by singlet oxygen. Nature Communications. 10, 1380.","short":"W.-J. Kwak, H. Kim, Y.K. Petit, C. Leypold, T.T. Nguyen, N. Mahne, P. Redfern, L.A. Curtiss, H.-G. Jung, S.M. Borisov, S.A. Freunberger, Y.-K. Sun, Nature Communications 10 (2019).","mla":"Kwak, Won-Jin, et al. “Deactivation of Redox Mediators in Lithium-Oxygen Batteries by Singlet Oxygen.” <i>Nature Communications</i>, vol. 10, 1380, Springer Nature, 2019, doi:<a href=\"https://doi.org/10.1038/s41467-019-09399-0\">10.1038/s41467-019-09399-0</a>.","chicago":"Kwak, Won-Jin, Hun Kim, Yann K. Petit, Christian Leypold, Trung Thien Nguyen, Nika Mahne, Paul Redfern, et al. “Deactivation of Redox Mediators in Lithium-Oxygen Batteries by Singlet Oxygen.” <i>Nature Communications</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41467-019-09399-0\">https://doi.org/10.1038/s41467-019-09399-0</a>.","ieee":"W.-J. Kwak <i>et al.</i>, “Deactivation of redox mediators in lithium-oxygen batteries by singlet oxygen,” <i>Nature Communications</i>, vol. 10. Springer Nature, 2019.","apa":"Kwak, W.-J., Kim, H., Petit, Y. K., Leypold, C., Nguyen, T. T., Mahne, N., … Sun, Y.-K. (2019). Deactivation of redox mediators in lithium-oxygen batteries by singlet oxygen. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-019-09399-0\">https://doi.org/10.1038/s41467-019-09399-0</a>","ama":"Kwak W-J, Kim H, Petit YK, et al. Deactivation of redox mediators in lithium-oxygen batteries by singlet oxygen. <i>Nature Communications</i>. 2019;10. doi:<a href=\"https://doi.org/10.1038/s41467-019-09399-0\">10.1038/s41467-019-09399-0</a>"},"date_updated":"2021-01-12T08:12:44Z","ddc":["540"],"extern":"1","volume":10,"intvolume":"        10","title":"Deactivation of redox mediators in lithium-oxygen batteries by singlet oxygen","date_created":"2020-01-15T12:12:26Z","article_processing_charge":"No","publication_status":"published","author":[{"first_name":"Won-Jin","last_name":"Kwak","full_name":"Kwak, Won-Jin"},{"full_name":"Kim, Hun","first_name":"Hun","last_name":"Kim"},{"full_name":"Petit, Yann K.","last_name":"Petit","first_name":"Yann K."},{"first_name":"Christian","last_name":"Leypold","full_name":"Leypold, Christian"},{"full_name":"Nguyen, Trung Thien","first_name":"Trung Thien","last_name":"Nguyen"},{"full_name":"Mahne, Nika","first_name":"Nika","last_name":"Mahne"},{"first_name":"Paul","last_name":"Redfern","full_name":"Redfern, Paul"},{"last_name":"Curtiss","first_name":"Larry A.","full_name":"Curtiss, Larry A."},{"last_name":"Jung","first_name":"Hun-Gi","full_name":"Jung, Hun-Gi"},{"full_name":"Borisov, Sergey M.","last_name":"Borisov","first_name":"Sergey M."},{"first_name":"Stefan Alexander","last_name":"Freunberger","orcid":"0000-0003-2902-5319","full_name":"Freunberger, Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425"},{"last_name":"Sun","first_name":"Yang-Kook","full_name":"Sun, Yang-Kook"}],"_id":"7280","article_type":"original","publisher":"Springer Nature","file_date_updated":"2020-07-14T12:47:55Z","quality_controlled":"1"},{"oa":1,"abstract":[{"lang":"eng","text":"The number of human genomes being genotyped or sequenced increases exponentially and efficient haplotype estimation methods able to handle this amount of data are now required. Here we present a method, SHAPEIT4, which substantially improves upon other methods to process large genotype and high coverage sequencing datasets. It notably exhibits sub-linear running times with sample size, provides highly accurate haplotypes and allows integrating external phasing information such as large reference panels of haplotypes, collections of pre-phased variants and long sequencing reads. We provide SHAPEIT4 in an open source format and demonstrate its performance in terms of accuracy and running times on two gold standard datasets: the UK Biobank data and the Genome In A Bottle."}],"publication_identifier":{"issn":["2041-1723"]},"day":"28","doi":"10.1038/s41467-019-13225-y","type":"journal_article","date_published":"2019-11-28T00:00:00Z","citation":{"apa":"Delaneau, O., Zagury, J.-F., Robinson, M. R., Marchini, J. L., &#38; Dermitzakis, E. T. (2019). Accurate, scalable and integrative haplotype estimation. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-019-13225-y\">https://doi.org/10.1038/s41467-019-13225-y</a>","ama":"Delaneau O, Zagury J-F, Robinson MR, Marchini JL, Dermitzakis ET. Accurate, scalable and integrative haplotype estimation. <i>Nature Communications</i>. 2019;10. doi:<a href=\"https://doi.org/10.1038/s41467-019-13225-y\">10.1038/s41467-019-13225-y</a>","ieee":"O. Delaneau, J.-F. Zagury, M. R. Robinson, J. L. Marchini, and E. T. Dermitzakis, “Accurate, scalable and integrative haplotype estimation,” <i>Nature Communications</i>, vol. 10. Springer Nature, 2019.","chicago":"Delaneau, Olivier, Jean-François Zagury, Matthew Richard Robinson, Jonathan L. Marchini, and Emmanouil T. Dermitzakis. “Accurate, Scalable and Integrative Haplotype Estimation.” <i>Nature Communications</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41467-019-13225-y\">https://doi.org/10.1038/s41467-019-13225-y</a>.","short":"O. Delaneau, J.-F. Zagury, M.R. Robinson, J.L. Marchini, E.T. Dermitzakis, Nature Communications 10 (2019).","mla":"Delaneau, Olivier, et al. “Accurate, Scalable and Integrative Haplotype Estimation.” <i>Nature Communications</i>, vol. 10, 5436, Springer Nature, 2019, doi:<a href=\"https://doi.org/10.1038/s41467-019-13225-y\">10.1038/s41467-019-13225-y</a>.","ista":"Delaneau O, Zagury J-F, Robinson MR, Marchini JL, Dermitzakis ET. 2019. Accurate, scalable and integrative haplotype estimation. Nature Communications. 10, 5436."},"year":"2019","date_updated":"2021-01-12T08:15:01Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-019-13225-y"}],"volume":10,"article_number":"5436","intvolume":"        10","month":"11","title":"Accurate, scalable and integrative haplotype estimation","date_created":"2020-04-30T10:40:32Z","article_processing_charge":"No","oa_version":"Published Version","publication_status":"published","author":[{"full_name":"Delaneau, Olivier","first_name":"Olivier","last_name":"Delaneau"},{"full_name":"Zagury, Jean-François","first_name":"Jean-François","last_name":"Zagury"},{"id":"E5D42276-F5DA-11E9-8E24-6303E6697425","last_name":"Robinson","first_name":"Matthew Richard","full_name":"Robinson, Matthew Richard","orcid":"0000-0001-8982-8813"},{"first_name":"Jonathan L.","last_name":"Marchini","full_name":"Marchini, Jonathan L."},{"full_name":"Dermitzakis, Emmanouil T.","last_name":"Dermitzakis","first_name":"Emmanouil T."}],"_id":"7710","publication":"Nature Communications","article_type":"original","publisher":"Springer Nature","language":[{"iso":"eng"}],"quality_controlled":"1"},{"volume":10,"ddc":["530"],"doi":"10.1038/s41467-019-08551-0","arxiv":1,"day":"08","abstract":[{"lang":"eng","text":"Speed of sound waves in gases and liquids are governed by the compressibility of the medium. There exists another type of non-dispersive wave where the wave speed depends on stress instead of elasticity of the medium. A well-known example is the Alfven wave, which propagates through plasma permeated by a magnetic field with the speed determined by magnetic tension. An elastic analogue of Alfven waves has been predicted in a flow of dilute polymer solution where the elastic stress of the stretching polymers determines the elastic wave speed. Here we present quantitative evidence of elastic Alfven waves in elastic turbulence of a viscoelastic creeping flow between two obstacles in channel flow. The key finding in the experimental proof is a nonlinear dependence of the elastic wave speed cel on the Weissenberg number Wi, which deviates from predictions based on a model of linear polymer elasticity."}],"date_updated":"2023-09-08T11:39:54Z","year":"2019","citation":{"ista":"Varshney A, Steinberg V. 2019. Elastic alfven waves in elastic turbulence. Nature Communications. 10, 652.","short":"A. Varshney, V. Steinberg, Nature Communications 10 (2019).","mla":"Varshney, Atul, and Victor Steinberg. “Elastic Alfven Waves in Elastic Turbulence.” <i>Nature Communications</i>, vol. 10, 652, Springer Nature, 2019, doi:<a href=\"https://doi.org/10.1038/s41467-019-08551-0\">10.1038/s41467-019-08551-0</a>.","ieee":"A. Varshney and V. Steinberg, “Elastic alfven waves in elastic turbulence,” <i>Nature Communications</i>, vol. 10. Springer Nature, 2019.","chicago":"Varshney, Atul, and Victor Steinberg. “Elastic Alfven Waves in Elastic Turbulence.” <i>Nature Communications</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41467-019-08551-0\">https://doi.org/10.1038/s41467-019-08551-0</a>.","ama":"Varshney A, Steinberg V. Elastic alfven waves in elastic turbulence. <i>Nature Communications</i>. 2019;10. doi:<a href=\"https://doi.org/10.1038/s41467-019-08551-0\">10.1038/s41467-019-08551-0</a>","apa":"Varshney, A., &#38; Steinberg, V. (2019). Elastic alfven waves in elastic turbulence. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-019-08551-0\">https://doi.org/10.1038/s41467-019-08551-0</a>"},"isi":1,"external_id":{"arxiv":["1902.03763"],"isi":["000458175300001"]},"publisher":"Springer Nature","article_type":"original","quality_controlled":"1","ec_funded":1,"file_date_updated":"2020-07-14T12:47:17Z","publication_status":"published","date_created":"2019-02-15T07:10:46Z","department":[{"_id":"BjHo"}],"article_processing_charge":"No","title":"Elastic alfven waves in elastic turbulence","intvolume":"        10","_id":"6014","scopus_import":"1","author":[{"id":"2A2006B2-F248-11E8-B48F-1D18A9856A87","first_name":"Atul","last_name":"Varshney","orcid":"0000-0002-3072-5999","full_name":"Varshney, Atul"},{"full_name":"Steinberg, Victor","first_name":"Victor","last_name":"Steinberg"}],"file":[{"file_name":"2019_NatureComm_Varshney.pdf","content_type":"application/pdf","date_updated":"2020-07-14T12:47:17Z","file_size":1331490,"checksum":"d3acf07eaad95ec040d8e8565fc9ac37","date_created":"2019-02-15T07:15:00Z","creator":"dernst","file_id":"6015","access_level":"open_access","relation":"main_file"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","status":"public","publication_identifier":{"issn":["2041-1723"]},"oa":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_published":"2019-02-08T00:00:00Z","type":"journal_article","language":[{"iso":"eng"}],"oa_version":"Published Version","project":[{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"month":"02","article_number":"652","publication":"Nature Communications","has_accepted_license":"1"},{"article_processing_charge":"No","date_created":"2019-03-05T13:18:30Z","department":[{"_id":"BjHo"}],"publication_status":"published","intvolume":"        10","title":"Stokes flow analogous to viscous electron current in graphene","scopus_import":"1","_id":"6069","author":[{"full_name":"Mayzel, Jonathan","first_name":"Jonathan","last_name":"Mayzel"},{"first_name":"Victor","last_name":"Steinberg","full_name":"Steinberg, Victor"},{"id":"2A2006B2-F248-11E8-B48F-1D18A9856A87","first_name":"Atul","last_name":"Varshney","orcid":"0000-0002-3072-5999","full_name":"Varshney, Atul"}],"publisher":"Springer Nature","ec_funded":1,"quality_controlled":"1","file_date_updated":"2020-07-14T12:47:18Z","day":"26","doi":"10.1038/s41467-019-08916-5","abstract":[{"lang":"eng","text":"Electron transport in two-dimensional conducting materials such as graphene, with dominant electron–electron interaction, exhibits unusual vortex flow that leads to a nonlocal current-field relation (negative resistance), distinct from the classical Ohm’s law. The transport behavior of these materials is best described by low Reynolds number hydrodynamics, where the constitutive pressure–speed relation is Stoke’s law. Here we report evidence of such vortices observed in a viscous flow of Newtonian fluid in a microfluidic device consisting of a rectangular cavity—analogous to the electronic system. We extend our experimental observations to elliptic cavities of different eccentricities, and validate them by numerically solving bi-harmonic equation obtained for the viscous flow with no-slip boundary conditions. We verify the existence of a  predicted threshold at which vortices appear. Strikingly, we find that a two-dimensional theoretical model captures the essential features of three-dimensional Stokes flow in experiments."}],"citation":{"ista":"Mayzel J, Steinberg V, Varshney A. 2019. Stokes flow analogous to viscous electron current in graphene. Nature Communications. 10, 937.","mla":"Mayzel, Jonathan, et al. “Stokes Flow Analogous to Viscous Electron Current in Graphene.” <i>Nature Communications</i>, vol. 10, 937, Springer Nature, 2019, doi:<a href=\"https://doi.org/10.1038/s41467-019-08916-5\">10.1038/s41467-019-08916-5</a>.","short":"J. Mayzel, V. Steinberg, A. Varshney, Nature Communications 10 (2019).","ieee":"J. Mayzel, V. Steinberg, and A. Varshney, “Stokes flow analogous to viscous electron current in graphene,” <i>Nature Communications</i>, vol. 10. Springer Nature, 2019.","chicago":"Mayzel, Jonathan, Victor Steinberg, and Atul Varshney. “Stokes Flow Analogous to Viscous Electron Current in Graphene.” <i>Nature Communications</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41467-019-08916-5\">https://doi.org/10.1038/s41467-019-08916-5</a>.","ama":"Mayzel J, Steinberg V, Varshney A. Stokes flow analogous to viscous electron current in graphene. <i>Nature Communications</i>. 2019;10. doi:<a href=\"https://doi.org/10.1038/s41467-019-08916-5\">10.1038/s41467-019-08916-5</a>","apa":"Mayzel, J., Steinberg, V., &#38; Varshney, A. (2019). Stokes flow analogous to viscous electron current in graphene. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-019-08916-5\">https://doi.org/10.1038/s41467-019-08916-5</a>"},"year":"2019","date_updated":"2023-09-08T11:39:02Z","external_id":{"isi":["000459704600001"]},"isi":1,"volume":10,"ddc":["530","532"],"project":[{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"oa_version":"Published Version","article_number":"937","month":"02","has_accepted_license":"1","publication":"Nature Communications","language":[{"iso":"eng"}],"publication_identifier":{"issn":["2041-1723"]},"oa":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"journal_article","date_published":"2019-02-26T00:00:00Z","file":[{"date_created":"2019-03-05T13:33:04Z","file_size":2646391,"checksum":"61192fc49e0d44907c2a4fe384e4b97f","date_updated":"2020-07-14T12:47:18Z","content_type":"application/pdf","file_name":"2019_NatureComm_Mayzel.pdf","access_level":"open_access","relation":"main_file","file_id":"6070","creator":"dernst"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","status":"public"},{"status":"public","user_id":"D865714E-FA4E-11E9-B85B-F5C5E5697425","file":[{"creator":"cziletti","file_id":"9061","success":1,"relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_name":"2019_NatureComm_Ramananarivo.pdf","date_updated":"2021-02-02T13:47:21Z","checksum":"70c6e5d6fbea0932b0669505ab6633ec","file_size":2820337,"date_created":"2021-02-02T13:47:21Z"}],"date_published":"2019-07-29T00:00:00Z","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"publication_identifier":{"issn":["2041-1723"]},"language":[{"iso":"eng"}],"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"publication":"Nature Communications","has_accepted_license":"1","month":"07","article_number":"3380","oa_version":"Published Version","extern":"1","ddc":["530"],"volume":10,"external_id":{"pmid":["31358762"],"arxiv":["1909.07382"]},"date_updated":"2023-02-23T13:47:59Z","citation":{"chicago":"Ramananarivo, Sophie, Etienne Ducrot, and Jérémie A Palacci. “Activity-Controlled Annealing of Colloidal Monolayers.” <i>Nature Communications</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41467-019-11362-y\">https://doi.org/10.1038/s41467-019-11362-y</a>.","ieee":"S. Ramananarivo, E. Ducrot, and J. A. Palacci, “Activity-controlled annealing of colloidal monolayers,” <i>Nature Communications</i>, vol. 10, no. 1. Springer Nature, 2019.","ama":"Ramananarivo S, Ducrot E, Palacci JA. Activity-controlled annealing of colloidal monolayers. <i>Nature Communications</i>. 2019;10(1). doi:<a href=\"https://doi.org/10.1038/s41467-019-11362-y\">10.1038/s41467-019-11362-y</a>","apa":"Ramananarivo, S., Ducrot, E., &#38; Palacci, J. A. (2019). Activity-controlled annealing of colloidal monolayers. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-019-11362-y\">https://doi.org/10.1038/s41467-019-11362-y</a>","ista":"Ramananarivo S, Ducrot E, Palacci JA. 2019. Activity-controlled annealing of colloidal monolayers. Nature Communications. 10(1), 3380.","mla":"Ramananarivo, Sophie, et al. “Activity-Controlled Annealing of Colloidal Monolayers.” <i>Nature Communications</i>, vol. 10, no. 1, 3380, Springer Nature, 2019, doi:<a href=\"https://doi.org/10.1038/s41467-019-11362-y\">10.1038/s41467-019-11362-y</a>.","short":"S. Ramananarivo, E. Ducrot, J.A. Palacci, Nature Communications 10 (2019)."},"year":"2019","abstract":[{"lang":"eng","text":"Molecular motors are essential to the living, generating fluctuations that boost transport and assist assembly. Active colloids, that consume energy to move, hold similar potential for man-made materials controlled by forces generated from within. Yet, their use as a powerhouse in materials science lacks. Here we show a massive acceleration of the annealing of a monolayer of passive beads by moderate addition of self-propelled microparticles. We rationalize our observations with a model of collisions that drive active fluctuations and activate the annealing. The experiment is quantitatively compared with Brownian dynamic simulations that further unveil a dynamical transition in the mechanism of annealing. Active dopants travel uniformly in the system or co-localize at the grain boundaries as a result of the persistence of their motion. Our findings uncover the potential of internal activity to control materials and lay the groundwork for the rise of materials science beyond equilibrium."}],"doi":"10.1038/s41467-019-11362-y","arxiv":1,"day":"29","file_date_updated":"2021-02-02T13:47:21Z","quality_controlled":"1","article_type":"original","publisher":"Springer Nature","author":[{"last_name":"Ramananarivo","first_name":"Sophie","full_name":"Ramananarivo, Sophie"},{"full_name":"Ducrot, Etienne","last_name":"Ducrot","first_name":"Etienne"},{"id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d","full_name":"Palacci, Jérémie A","orcid":"0000-0002-7253-9465","last_name":"Palacci","first_name":"Jérémie A"}],"issue":"1","_id":"9060","pmid":1,"scopus_import":"1","title":"Activity-controlled annealing of colloidal monolayers","intvolume":"        10","publication_status":"published","date_created":"2021-02-02T13:43:36Z","article_processing_charge":"No"},{"publication":"Nature Communications","has_accepted_license":"1","oa_version":"Published Version","month":"09","language":[{"iso":"eng"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_published":"2018-09-28T00:00:00Z","type":"journal_article","publication_identifier":{"issn":["2041-1723"]},"oa":1,"file":[{"date_updated":"2020-07-14T12:47:48Z","file_name":"2018_NatureComm_Modic.pdf","content_type":"application/pdf","date_created":"2019-11-20T12:48:58Z","checksum":"46a313c816e66899d4dad2cf3583e5b0","file_size":1257681,"file_id":"7088","creator":"dernst","relation":"main_file","access_level":"open_access"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","_id":"7059","author":[{"first_name":"Kimberly A","last_name":"Modic","orcid":"0000-0001-9760-3147","full_name":"Modic, Kimberly A","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425"},{"first_name":"Maja D.","last_name":"Bachmann","full_name":"Bachmann, Maja D."},{"full_name":"Ramshaw, B. J.","last_name":"Ramshaw","first_name":"B. J."},{"first_name":"F.","last_name":"Arnold","full_name":"Arnold, F."},{"last_name":"Shirer","first_name":"K. R.","full_name":"Shirer, K. R."},{"first_name":"Amelia","last_name":"Estry","full_name":"Estry, Amelia"},{"first_name":"J. B.","last_name":"Betts","full_name":"Betts, J. B."},{"first_name":"Nirmal J.","last_name":"Ghimire","full_name":"Ghimire, Nirmal J."},{"last_name":"Bauer","first_name":"E. D.","full_name":"Bauer, E. D."},{"last_name":"Schmidt","first_name":"Marcus","full_name":"Schmidt, Marcus"},{"full_name":"Baenitz, Michael","first_name":"Michael","last_name":"Baenitz"},{"full_name":"Svanidze, E.","first_name":"E.","last_name":"Svanidze"},{"full_name":"McDonald, Ross D.","last_name":"McDonald","first_name":"Ross D."},{"full_name":"Shekhter, Arkady","last_name":"Shekhter","first_name":"Arkady"},{"full_name":"Moll, Philip J. W.","last_name":"Moll","first_name":"Philip J. W."}],"issue":"1","publication_status":"published","date_created":"2019-11-19T13:02:20Z","article_processing_charge":"No","title":"Resonant torsion magnetometry in anisotropic quantum materials","intvolume":"         9","page":"3975","quality_controlled":"1","file_date_updated":"2020-07-14T12:47:48Z","publisher":"Springer Nature","article_type":"original","date_updated":"2021-01-12T08:11:37Z","year":"2018","citation":{"ista":"Modic KA, Bachmann MD, Ramshaw BJ, Arnold F, Shirer KR, Estry A, Betts JB, Ghimire NJ, Bauer ED, Schmidt M, Baenitz M, Svanidze E, McDonald RD, Shekhter A, Moll PJW. 2018. Resonant torsion magnetometry in anisotropic quantum materials. Nature Communications. 9(1), 3975.","mla":"Modic, Kimberly A., et al. “Resonant Torsion Magnetometry in Anisotropic Quantum Materials.” <i>Nature Communications</i>, vol. 9, no. 1, Springer Nature, 2018, p. 3975, doi:<a href=\"https://doi.org/10.1038/s41467-018-06412-w\">10.1038/s41467-018-06412-w</a>.","short":"K.A. Modic, M.D. Bachmann, B.J. Ramshaw, F. Arnold, K.R. Shirer, A. Estry, J.B. Betts, N.J. Ghimire, E.D. Bauer, M. Schmidt, M. Baenitz, E. Svanidze, R.D. McDonald, A. Shekhter, P.J.W. Moll, Nature Communications 9 (2018) 3975.","chicago":"Modic, Kimberly A, Maja D. Bachmann, B. J. Ramshaw, F. Arnold, K. R. Shirer, Amelia Estry, J. B. Betts, et al. “Resonant Torsion Magnetometry in Anisotropic Quantum Materials.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-018-06412-w\">https://doi.org/10.1038/s41467-018-06412-w</a>.","ieee":"K. A. Modic <i>et al.</i>, “Resonant torsion magnetometry in anisotropic quantum materials,” <i>Nature Communications</i>, vol. 9, no. 1. Springer Nature, p. 3975, 2018.","apa":"Modic, K. A., Bachmann, M. D., Ramshaw, B. J., Arnold, F., Shirer, K. R., Estry, A., … Moll, P. J. W. (2018). Resonant torsion magnetometry in anisotropic quantum materials. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-018-06412-w\">https://doi.org/10.1038/s41467-018-06412-w</a>","ama":"Modic KA, Bachmann MD, Ramshaw BJ, et al. Resonant torsion magnetometry in anisotropic quantum materials. <i>Nature Communications</i>. 2018;9(1):3975. doi:<a href=\"https://doi.org/10.1038/s41467-018-06412-w\">10.1038/s41467-018-06412-w</a>"},"doi":"10.1038/s41467-018-06412-w","day":"28","abstract":[{"lang":"eng","text":"Unusual behavior in quantum materials commonly arises from their effective low-dimensional physics, reflecting the underlying anisotropy in the spin and charge degrees of freedom. Here we introduce the magnetotropic coefficient k = ∂2F/∂θ2, the second derivative of the free energy F with respect to the magnetic field orientation θ in the crystal. We show that the magnetotropic coefficient can be quantitatively determined from a shift in the resonant frequency of a commercially available atomic force microscopy cantilever under magnetic field. This detection method enables part per 100 million sensitivity and the ability to measure magnetic anisotropy in nanogram-scale samples, as demonstrated on the Weyl semimetal NbP. Measurement of the magnetotropic coefficient in the spin-liquid candidate RuCl3 highlights its sensitivity to anisotropic phase transitions and allows a quantitative comparison to other thermodynamic coefficients via the Ehrenfest relations."}],"volume":9,"extern":"1","ddc":["530"]},{"publication":"Nature Communications","has_accepted_license":"1","oa_version":"Published Version","month":"06","article_number":"2217","language":[{"iso":"eng"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_published":"2018-06-07T00:00:00Z","type":"journal_article","publication_identifier":{"issn":["2041-1723"]},"oa":1,"file":[{"creator":"dernst","file_id":"7089","access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_name":"2018_NatureComm_Ramshaw.pdf","date_updated":"2020-07-14T12:47:48Z","file_size":1794797,"checksum":"9c53f9a1f06a4d83d5fe879d2478b7d7","date_created":"2019-11-20T13:55:44Z"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","_id":"7062","author":[{"first_name":"B. J.","last_name":"Ramshaw","full_name":"Ramshaw, B. J."},{"id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","first_name":"Kimberly A","last_name":"Modic","orcid":"0000-0001-9760-3147","full_name":"Modic, Kimberly A"},{"full_name":"Shekhter, Arkady","first_name":"Arkady","last_name":"Shekhter"},{"full_name":"Zhang, Yi","first_name":"Yi","last_name":"Zhang"},{"full_name":"Kim, Eun-Ah","last_name":"Kim","first_name":"Eun-Ah"},{"first_name":"Philip J. W.","last_name":"Moll","full_name":"Moll, Philip J. W."},{"full_name":"Bachmann, Maja D.","last_name":"Bachmann","first_name":"Maja D."},{"first_name":"M. K.","last_name":"Chan","full_name":"Chan, M. K."},{"first_name":"J. B.","last_name":"Betts","full_name":"Betts, J. B."},{"first_name":"F.","last_name":"Balakirev","full_name":"Balakirev, F."},{"full_name":"Migliori, A.","last_name":"Migliori","first_name":"A."},{"first_name":"N. J.","last_name":"Ghimire","full_name":"Ghimire, N. J."},{"full_name":"Bauer, E. D.","first_name":"E. D.","last_name":"Bauer"},{"first_name":"F.","last_name":"Ronning","full_name":"Ronning, F."},{"full_name":"McDonald, R. D.","first_name":"R. D.","last_name":"McDonald"}],"issue":"1","publication_status":"published","article_processing_charge":"No","date_created":"2019-11-19T13:10:33Z","title":"Quantum limit transport and destruction of the Weyl nodes in TaAs","intvolume":"         9","quality_controlled":"1","file_date_updated":"2020-07-14T12:47:48Z","publisher":"Springer Nature","article_type":"original","date_updated":"2021-01-12T08:11:38Z","citation":{"short":"B.J. Ramshaw, K.A. Modic, A. Shekhter, Y. Zhang, E.-A. Kim, P.J.W. Moll, M.D. Bachmann, M.K. Chan, J.B. Betts, F. Balakirev, A. Migliori, N.J. Ghimire, E.D. Bauer, F. Ronning, R.D. McDonald, Nature Communications 9 (2018).","mla":"Ramshaw, B. J., et al. “Quantum Limit Transport and Destruction of the Weyl Nodes in TaAs.” <i>Nature Communications</i>, vol. 9, no. 1, 2217, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-018-04542-9\">10.1038/s41467-018-04542-9</a>.","ista":"Ramshaw BJ, Modic KA, Shekhter A, Zhang Y, Kim E-A, Moll PJW, Bachmann MD, Chan MK, Betts JB, Balakirev F, Migliori A, Ghimire NJ, Bauer ED, Ronning F, McDonald RD. 2018. Quantum limit transport and destruction of the Weyl nodes in TaAs. Nature Communications. 9(1), 2217.","apa":"Ramshaw, B. J., Modic, K. A., Shekhter, A., Zhang, Y., Kim, E.-A., Moll, P. J. W., … McDonald, R. D. (2018). Quantum limit transport and destruction of the Weyl nodes in TaAs. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-018-04542-9\">https://doi.org/10.1038/s41467-018-04542-9</a>","ama":"Ramshaw BJ, Modic KA, Shekhter A, et al. Quantum limit transport and destruction of the Weyl nodes in TaAs. <i>Nature Communications</i>. 2018;9(1). doi:<a href=\"https://doi.org/10.1038/s41467-018-04542-9\">10.1038/s41467-018-04542-9</a>","chicago":"Ramshaw, B. J., Kimberly A Modic, Arkady Shekhter, Yi Zhang, Eun-Ah Kim, Philip J. W. Moll, Maja D. Bachmann, et al. “Quantum Limit Transport and Destruction of the Weyl Nodes in TaAs.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-018-04542-9\">https://doi.org/10.1038/s41467-018-04542-9</a>.","ieee":"B. J. Ramshaw <i>et al.</i>, “Quantum limit transport and destruction of the Weyl nodes in TaAs,” <i>Nature Communications</i>, vol. 9, no. 1. Springer Nature, 2018."},"year":"2018","doi":"10.1038/s41467-018-04542-9","day":"07","abstract":[{"lang":"eng","text":"Weyl fermions are a recently discovered ingredient for correlated states of electronic matter. A key difficulty has been that real materials also contain non-Weyl quasiparticles, and disentangling the experimental signatures has proven challenging. Here we use magnetic fields up to 95 T to drive the Weyl semimetal TaAs far into its quantum limit, where only the purely chiral 0th Landau levels of the Weyl fermions are occupied. We find the electrical resistivity to be nearly independent of magnetic field up to 50 T: unusual for conventional metals but consistent with the chiral anomaly for Weyl fermions. Above 50 T we observe a two-order-of-magnitude increase in resistivity, indicating that a gap opens in the chiral Landau levels. Above 80 T we observe strong ultrasonic attenuation below 2 K, suggesting a mesoscopically textured state of matter. These results point the way to inducing new correlated states of matter in the quantum limit of Weyl semimetals."}],"volume":9,"extern":"1","ddc":["530"]},{"author":[{"last_name":"Yap","first_name":"Chloe X.","full_name":"Yap, Chloe X."},{"last_name":"Sidorenko","first_name":"Julia","full_name":"Sidorenko, Julia"},{"first_name":"Yang","last_name":"Wu","full_name":"Wu, Yang"},{"first_name":"Kathryn E.","last_name":"Kemper","full_name":"Kemper, Kathryn E."},{"full_name":"Yang, Jian","last_name":"Yang","first_name":"Jian"},{"full_name":"Wray, Naomi R.","last_name":"Wray","first_name":"Naomi R."},{"id":"E5D42276-F5DA-11E9-8E24-6303E6697425","last_name":"Robinson","first_name":"Matthew Richard","full_name":"Robinson, Matthew Richard","orcid":"0000-0001-8982-8813"},{"full_name":"Visscher, Peter M.","last_name":"Visscher","first_name":"Peter M."}],"publication":"Nature Communications","_id":"7712","title":"Dissection of genetic variation and evidence for pleiotropy in male pattern baldness","month":"12","article_number":"5407","intvolume":"         9","oa_version":"Published Version","publication_status":"published","article_processing_charge":"No","date_created":"2020-04-30T10:41:19Z","language":[{"iso":"eng"}],"quality_controlled":"1","article_type":"original","publisher":"Springer Nature","date_published":"2018-12-20T00:00:00Z","type":"journal_article","date_updated":"2021-01-12T08:15:02Z","year":"2018","citation":{"mla":"Yap, Chloe X., et al. “Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness.” <i>Nature Communications</i>, vol. 9, 5407, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-018-07862-y\">10.1038/s41467-018-07862-y</a>.","short":"C.X. Yap, J. Sidorenko, Y. Wu, K.E. Kemper, J. Yang, N.R. Wray, M.R. Robinson, P.M. Visscher, Nature Communications 9 (2018).","ista":"Yap CX, Sidorenko J, Wu Y, Kemper KE, Yang J, Wray NR, Robinson MR, Visscher PM. 2018. Dissection of genetic variation and evidence for pleiotropy in male pattern baldness. Nature Communications. 9, 5407.","apa":"Yap, C. X., Sidorenko, J., Wu, Y., Kemper, K. E., Yang, J., Wray, N. R., … Visscher, P. M. (2018). Dissection of genetic variation and evidence for pleiotropy in male pattern baldness. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-018-07862-y\">https://doi.org/10.1038/s41467-018-07862-y</a>","ama":"Yap CX, Sidorenko J, Wu Y, et al. Dissection of genetic variation and evidence for pleiotropy in male pattern baldness. <i>Nature Communications</i>. 2018;9. doi:<a href=\"https://doi.org/10.1038/s41467-018-07862-y\">10.1038/s41467-018-07862-y</a>","ieee":"C. X. Yap <i>et al.</i>, “Dissection of genetic variation and evidence for pleiotropy in male pattern baldness,” <i>Nature Communications</i>, vol. 9. Springer Nature, 2018.","chicago":"Yap, Chloe X., Julia Sidorenko, Yang Wu, Kathryn E. Kemper, Jian Yang, Naomi R. Wray, Matthew Richard Robinson, and Peter M. Visscher. “Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-018-07862-y\">https://doi.org/10.1038/s41467-018-07862-y</a>."},"abstract":[{"lang":"eng","text":"Male pattern baldness (MPB) is a sex-limited, age-related, complex trait. We study MPB genetics in 205,327 European males from the UK Biobank. Here we show that MPB is strongly heritable and polygenic, with pedigree-heritability of 0.62 (SE = 0.03) estimated from close relatives, and SNP-heritability of 0.39 (SE = 0.01) from conventionally-unrelated males. We detect 624 near-independent genome-wide loci, contributing SNP-heritability of 0.25 (SE = 0.01), of which 26 X-chromosome loci explain 11.6%. Autosomal genetic variance is enriched for common variants and regions of lower linkage disequilibrium. We identify plausible genetic correlations between MPB and multiple sex-limited markers of earlier puberty, increased bone mineral density (rg = 0.15) and pancreatic β-cell function (rg = 0.12). Correlations with reproductive traits imply an effect on fitness, consistent with an estimated linear selection gradient of -0.018 per MPB standard deviation. Overall, we provide genetic insights into MPB: a phenotype of interest in its own right, with value as a model sex-limited, complex trait."}],"oa":1,"doi":"10.1038/s41467-018-07862-y","day":"20","publication_identifier":{"issn":["2041-1723"]},"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","volume":9,"main_file_link":[{"url":"https://doi.org/10.1038/s41467-018-07862-y","open_access":"1"}]},{"year":"2018","citation":{"short":"J. Guo, Y. Wu, Z. Zhu, Z. Zheng, M. Trzaskowski, J. Zeng, M.R. Robinson, P.M. Visscher, J. Yang, Nature Communications 9 (2018).","mla":"Guo, Jing, et al. “Global Genetic Differentiation of Complex Traits Shaped by Natural Selection in Humans.” <i>Nature Communications</i>, vol. 9, 1865, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-018-04191-y\">10.1038/s41467-018-04191-y</a>.","ista":"Guo J, Wu Y, Zhu Z, Zheng Z, Trzaskowski M, Zeng J, Robinson MR, Visscher PM, Yang J. 2018. Global genetic differentiation of complex traits shaped by natural selection in humans. Nature Communications. 9, 1865.","ama":"Guo J, Wu Y, Zhu Z, et al. Global genetic differentiation of complex traits shaped by natural selection in humans. <i>Nature Communications</i>. 2018;9. doi:<a href=\"https://doi.org/10.1038/s41467-018-04191-y\">10.1038/s41467-018-04191-y</a>","apa":"Guo, J., Wu, Y., Zhu, Z., Zheng, Z., Trzaskowski, M., Zeng, J., … Yang, J. (2018). Global genetic differentiation of complex traits shaped by natural selection in humans. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-018-04191-y\">https://doi.org/10.1038/s41467-018-04191-y</a>","ieee":"J. Guo <i>et al.</i>, “Global genetic differentiation of complex traits shaped by natural selection in humans,” <i>Nature Communications</i>, vol. 9. Springer Nature, 2018.","chicago":"Guo, Jing, Yang Wu, Zhihong Zhu, Zhili Zheng, Maciej Trzaskowski, Jian Zeng, Matthew Richard Robinson, Peter M. Visscher, and Jian Yang. “Global Genetic Differentiation of Complex Traits Shaped by Natural Selection in Humans.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-018-04191-y\">https://doi.org/10.1038/s41467-018-04191-y</a>."},"date_updated":"2021-01-12T08:15:02Z","type":"journal_article","date_published":"2018-05-14T00:00:00Z","day":"14","publication_identifier":{"issn":["2041-1723"]},"doi":"10.1038/s41467-018-04191-y","oa":1,"abstract":[{"lang":"eng","text":"There are mean differences in complex traits among global human populations. We hypothesize that part of the phenotypic differentiation is due to natural selection. To address this hypothesis, we assess the differentiation in allele frequencies of trait-associated SNPs among African, Eastern Asian, and European populations for ten complex traits using data of large sample size (up to ~405,000). We show that SNPs associated with height (P=2.46×10−5), waist-to-hip ratio (P=2.77×10−4), and schizophrenia (P=3.96×10−5) are significantly more differentiated among populations than matched “control” SNPs, suggesting that these trait-associated SNPs have undergone natural selection. We further find that SNPs associated with height (P=2.01×10−6) and schizophrenia (P=5.16×10−18) show significantly higher variance in linkage disequilibrium (LD) scores across populations than control SNPs. Our results support the hypothesis that natural selection has shaped the genetic differentiation of complex traits, such as height and schizophrenia, among worldwide populations."}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-018-04191-y"}],"volume":9,"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","_id":"7713","publication":"Nature Communications","author":[{"full_name":"Guo, Jing","last_name":"Guo","first_name":"Jing"},{"first_name":"Yang","last_name":"Wu","full_name":"Wu, Yang"},{"first_name":"Zhihong","last_name":"Zhu","full_name":"Zhu, Zhihong"},{"first_name":"Zhili","last_name":"Zheng","full_name":"Zheng, Zhili"},{"first_name":"Maciej","last_name":"Trzaskowski","full_name":"Trzaskowski, Maciej"},{"last_name":"Zeng","first_name":"Jian","full_name":"Zeng, Jian"},{"first_name":"Matthew Richard","last_name":"Robinson","orcid":"0000-0001-8982-8813","full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425"},{"last_name":"Visscher","first_name":"Peter M.","full_name":"Visscher, Peter M."},{"full_name":"Yang, Jian","last_name":"Yang","first_name":"Jian"}],"article_processing_charge":"No","date_created":"2020-04-30T10:41:36Z","oa_version":"Published Version","publication_status":"published","intvolume":"         9","article_number":"1865","month":"05","title":"Global genetic differentiation of complex traits shaped by natural selection in humans","quality_controlled":"1","language":[{"iso":"eng"}],"publisher":"Springer Nature","article_type":"original"},{"publication":"Nature Communications","_id":"7714","author":[{"first_name":"Zhihong","last_name":"Zhu","full_name":"Zhu, Zhihong"},{"full_name":"Zheng, Zhili","last_name":"Zheng","first_name":"Zhili"},{"full_name":"Zhang, Futao","last_name":"Zhang","first_name":"Futao"},{"full_name":"Wu, Yang","last_name":"Wu","first_name":"Yang"},{"full_name":"Trzaskowski, Maciej","first_name":"Maciej","last_name":"Trzaskowski"},{"full_name":"Maier, Robert","last_name":"Maier","first_name":"Robert"},{"id":"E5D42276-F5DA-11E9-8E24-6303E6697425","last_name":"Robinson","first_name":"Matthew Richard","full_name":"Robinson, Matthew Richard","orcid":"0000-0001-8982-8813"},{"last_name":"McGrath","first_name":"John J.","full_name":"McGrath, John J."},{"last_name":"Visscher","first_name":"Peter M.","full_name":"Visscher, Peter M."},{"first_name":"Naomi R.","last_name":"Wray","full_name":"Wray, Naomi R."},{"full_name":"Yang, Jian","first_name":"Jian","last_name":"Yang"}],"publication_status":"published","oa_version":"Published Version","article_processing_charge":"No","date_created":"2020-04-30T10:41:55Z","title":"Causal associations between risk factors and common diseases inferred from GWAS summary data","month":"01","intvolume":"         9","article_number":"224","quality_controlled":"1","language":[{"iso":"eng"}],"publisher":"Springer Nature","article_type":"original","date_updated":"2021-01-12T08:15:03Z","year":"2018","citation":{"chicago":"Zhu, Zhihong, Zhili Zheng, Futao Zhang, Yang Wu, Maciej Trzaskowski, Robert Maier, Matthew Richard Robinson, et al. “Causal Associations between Risk Factors and Common Diseases Inferred from GWAS Summary Data.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-017-02317-2\">https://doi.org/10.1038/s41467-017-02317-2</a>.","ieee":"Z. Zhu <i>et al.</i>, “Causal associations between risk factors and common diseases inferred from GWAS summary data,” <i>Nature Communications</i>, vol. 9. Springer Nature, 2018.","apa":"Zhu, Z., Zheng, Z., Zhang, F., Wu, Y., Trzaskowski, M., Maier, R., … Yang, J. (2018). Causal associations between risk factors and common diseases inferred from GWAS summary data. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-017-02317-2\">https://doi.org/10.1038/s41467-017-02317-2</a>","ama":"Zhu Z, Zheng Z, Zhang F, et al. Causal associations between risk factors and common diseases inferred from GWAS summary data. <i>Nature Communications</i>. 2018;9. doi:<a href=\"https://doi.org/10.1038/s41467-017-02317-2\">10.1038/s41467-017-02317-2</a>","ista":"Zhu Z, Zheng Z, Zhang F, Wu Y, Trzaskowski M, Maier R, Robinson MR, McGrath JJ, Visscher PM, Wray NR, Yang J. 2018. Causal associations between risk factors and common diseases inferred from GWAS summary data. Nature Communications. 9, 224.","short":"Z. Zhu, Z. Zheng, F. Zhang, Y. Wu, M. Trzaskowski, R. Maier, M.R. Robinson, J.J. McGrath, P.M. Visscher, N.R. Wray, J. Yang, Nature Communications 9 (2018).","mla":"Zhu, Zhihong, et al. “Causal Associations between Risk Factors and Common Diseases Inferred from GWAS Summary Data.” <i>Nature Communications</i>, vol. 9, 224, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-017-02317-2\">10.1038/s41467-017-02317-2</a>."},"date_published":"2018-01-15T00:00:00Z","type":"journal_article","doi":"10.1038/s41467-017-02317-2","publication_identifier":{"issn":["2041-1723"]},"day":"15","abstract":[{"lang":"eng","text":"Health risk factors such as body mass index (BMI) and serum cholesterol are associated with many common diseases. It often remains unclear whether the risk factors are cause or consequence of disease, or whether the associations are the result of confounding. We develop and apply a method (called GSMR) that performs a multi-SNP Mendelian randomization analysis using summary-level data from genome-wide association studies to test the causal associations of BMI, waist-to-hip ratio, serum cholesterols, blood pressures, height, and years of schooling (EduYears) with common diseases (sample sizes of up to 405,072). We identify a number of causal associations including a protective effect of LDL-cholesterol against type-2 diabetes (T2D) that might explain the side effects of statins on T2D, a protective effect of EduYears against Alzheimer’s disease, and bidirectional associations with opposite effects (e.g., higher BMI increases the risk of T2D but the effect of T2D on BMI is negative)."}],"oa":1,"volume":9,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-017-02317-2"}],"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public"},{"oa":1,"abstract":[{"text":"Genomic prediction has the potential to contribute to precision medicine. However, to date, the utility of such predictors is limited due to low accuracy for most traits. Here theory and simulation study are used to demonstrate that widespread pleiotropy among phenotypes can be utilised to improve genomic risk prediction. We show how a genetic predictor can be created as a weighted index that combines published genome-wide association study (GWAS) summary statistics across many different traits. We apply this framework to predict risk of schizophrenia and bipolar disorder in the Psychiatric Genomics consortium data, finding substantial heterogeneity in prediction accuracy increases across cohorts. For six additional phenotypes in the UK Biobank data, we find increases in prediction accuracy ranging from 0.7% for height to 47% for type 2 diabetes, when using a multi-trait predictor that combines published summary statistics from multiple traits, as compared to a predictor based only on one trait.","lang":"eng"}],"publication_identifier":{"issn":["2041-1723"]},"day":"07","doi":"10.1038/s41467-017-02769-6","type":"journal_article","date_published":"2018-03-07T00:00:00Z","year":"2018","citation":{"ama":"Maier RM, Zhu Z, Lee SH, et al. Improving genetic prediction by leveraging genetic correlations among human diseases and traits. <i>Nature Communications</i>. 2018;9. doi:<a href=\"https://doi.org/10.1038/s41467-017-02769-6\">10.1038/s41467-017-02769-6</a>","apa":"Maier, R. M., Zhu, Z., Lee, S. H., Trzaskowski, M., Ruderfer, D. M., Stahl, E. A., … Robinson, M. R. (2018). Improving genetic prediction by leveraging genetic correlations among human diseases and traits. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-017-02769-6\">https://doi.org/10.1038/s41467-017-02769-6</a>","ieee":"R. M. Maier <i>et al.</i>, “Improving genetic prediction by leveraging genetic correlations among human diseases and traits,” <i>Nature Communications</i>, vol. 9. Springer Nature, 2018.","chicago":"Maier, Robert M., Zhihong Zhu, Sang Hong Lee, Maciej Trzaskowski, Douglas M. Ruderfer, Eli A. Stahl, Stephan Ripke, et al. “Improving Genetic Prediction by Leveraging Genetic Correlations among Human Diseases and Traits.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-017-02769-6\">https://doi.org/10.1038/s41467-017-02769-6</a>.","short":"R.M. Maier, Z. Zhu, S.H. Lee, M. Trzaskowski, D.M. Ruderfer, E.A. Stahl, S. Ripke, N.R. Wray, J. Yang, P.M. Visscher, M.R. Robinson, Nature Communications 9 (2018).","mla":"Maier, Robert M., et al. “Improving Genetic Prediction by Leveraging Genetic Correlations among Human Diseases and Traits.” <i>Nature Communications</i>, vol. 9, 989, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-017-02769-6\">10.1038/s41467-017-02769-6</a>.","ista":"Maier RM, Zhu Z, Lee SH, Trzaskowski M, Ruderfer DM, Stahl EA, Ripke S, Wray NR, Yang J, Visscher PM, Robinson MR. 2018. Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nature Communications. 9, 989."},"date_updated":"2021-01-12T08:15:03Z","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-017-02769-6"}],"volume":9,"intvolume":"         9","article_number":"989","title":"Improving genetic prediction by leveraging genetic correlations among human diseases and traits","month":"03","article_processing_charge":"No","date_created":"2020-04-30T10:42:29Z","publication_status":"published","oa_version":"Published Version","author":[{"full_name":"Maier, Robert M.","last_name":"Maier","first_name":"Robert M."},{"full_name":"Zhu, Zhihong","first_name":"Zhihong","last_name":"Zhu"},{"full_name":"Lee, Sang Hong","first_name":"Sang Hong","last_name":"Lee"},{"full_name":"Trzaskowski, Maciej","last_name":"Trzaskowski","first_name":"Maciej"},{"last_name":"Ruderfer","first_name":"Douglas M.","full_name":"Ruderfer, Douglas M."},{"full_name":"Stahl, Eli A.","last_name":"Stahl","first_name":"Eli A."},{"full_name":"Ripke, Stephan","last_name":"Ripke","first_name":"Stephan"},{"full_name":"Wray, Naomi R.","first_name":"Naomi R.","last_name":"Wray"},{"full_name":"Yang, Jian","first_name":"Jian","last_name":"Yang"},{"last_name":"Visscher","first_name":"Peter M.","full_name":"Visscher, Peter M."},{"first_name":"Matthew Richard","last_name":"Robinson","orcid":"0000-0001-8982-8813","full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425"}],"_id":"7716","publication":"Nature Communications","article_type":"original","publisher":"Springer Nature","language":[{"iso":"eng"}],"quality_controlled":"1"},{"quality_controlled":"1","language":[{"iso":"eng"}],"publisher":"Springer Nature","article_type":"original","publication":"Nature Communications","_id":"7754","author":[{"id":"EB352CD2-F68A-11E9-89C5-A432E6697425","first_name":"Carl Peter","last_name":"Goodrich","orcid":"0000-0002-1307-5074","full_name":"Goodrich, Carl Peter"},{"first_name":"Michael P.","last_name":"Brenner","full_name":"Brenner, Michael P."},{"last_name":"Ribbeck","first_name":"Katharina","full_name":"Ribbeck, Katharina"}],"publication_status":"published","oa_version":"Published Version","article_processing_charge":"No","date_created":"2020-04-30T11:38:01Z","title":"Enhanced diffusion by binding to the crosslinks of a polymer gel","month":"10","article_number":"4348","intvolume":"         9","volume":9,"main_file_link":[{"url":"https://doi.org/10.1038/s41467-018-06851-5","open_access":"1"}],"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","date_updated":"2021-01-12T08:15:18Z","citation":{"ista":"Goodrich CP, Brenner MP, Ribbeck K. 2018. Enhanced diffusion by binding to the crosslinks of a polymer gel. Nature Communications. 9, 4348.","short":"C.P. Goodrich, M.P. Brenner, K. Ribbeck, Nature Communications 9 (2018).","mla":"Goodrich, Carl Peter, et al. “Enhanced Diffusion by Binding to the Crosslinks of a Polymer Gel.” <i>Nature Communications</i>, vol. 9, 4348, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-018-06851-5\">10.1038/s41467-018-06851-5</a>.","ieee":"C. P. Goodrich, M. P. Brenner, and K. Ribbeck, “Enhanced diffusion by binding to the crosslinks of a polymer gel,” <i>Nature Communications</i>, vol. 9. Springer Nature, 2018.","chicago":"Goodrich, Carl Peter, Michael P. Brenner, and Katharina Ribbeck. “Enhanced Diffusion by Binding to the Crosslinks of a Polymer Gel.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-018-06851-5\">https://doi.org/10.1038/s41467-018-06851-5</a>.","apa":"Goodrich, C. P., Brenner, M. P., &#38; Ribbeck, K. (2018). Enhanced diffusion by binding to the crosslinks of a polymer gel. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-018-06851-5\">https://doi.org/10.1038/s41467-018-06851-5</a>","ama":"Goodrich CP, Brenner MP, Ribbeck K. Enhanced diffusion by binding to the crosslinks of a polymer gel. <i>Nature Communications</i>. 2018;9. doi:<a href=\"https://doi.org/10.1038/s41467-018-06851-5\">10.1038/s41467-018-06851-5</a>"},"year":"2018","date_published":"2018-10-19T00:00:00Z","type":"journal_article","doi":"10.1038/s41467-018-06851-5","day":"19","publication_identifier":{"issn":["2041-1723"]},"abstract":[{"lang":"eng","text":"Creating a selective gel that filters particles based on their interactions is a major goal of nanotechnology, with far-reaching implications from drug delivery to controlling assembly pathways. However, this is particularly difficult when the particles are larger than the gel’s characteristic mesh size because such particles cannot passively pass through the gel. Thus, filtering requires the interacting particles to transiently reorganize the gel’s internal structure. While significant advances, e.g., in DNA engineering, have enabled the design of nano-materials with programmable interactions, it is not clear what physical principles such a designer gel could exploit to achieve selective permeability. We present an equilibrium mechanism where crosslink binding dynamics are affected by interacting particles such that particle diffusion is enhanced. In addition to revealing specific design rules for manufacturing selective gels, our results have the potential to explain the origin of selective permeability in certain biological materials, including the nuclear pore complex."}],"oa":1},{"ddc":["570"],"volume":9,"abstract":[{"lang":"eng","text":"G-protein-coupled receptors (GPCRs) form the largest receptor family, relay environmental stimuli to changes in cell behavior and represent prime drug targets. Many GPCRs are classified as orphan receptors because of the limited knowledge on their ligands and coupling to cellular signaling machineries. Here, we engineer a library of 63 chimeric receptors that contain the signaling domains of human orphan and understudied GPCRs functionally linked to the light-sensing domain of rhodopsin. Upon stimulation with visible light, we identify activation of canonical cell signaling pathways, including cAMP-, Ca2+-, MAPK/ERK-, and Rho-dependent pathways, downstream of the engineered receptors. For the human pseudogene GPR33, we resurrect a signaling function that supports its hypothesized role as a pathogen entry site. These results demonstrate that substituting unknown chemical activators with a light switch can reveal information about protein function and provide an optically controlled protein library for exploring the physiology and therapeutic potential of understudied GPCRs."}],"doi":"10.1038/s41467-018-04342-1","day":"01","isi":1,"external_id":{"isi":["000432280000006"]},"date_updated":"2023-09-19T14:29:32Z","citation":{"apa":"Morri, M., Sanchez-Romero, I., Tichy, A.-M., Kainrath, S., Gerrard, E. J., Hirschfeld, P., … Janovjak, H. L. (2018). Optical functionalization of human class A orphan G-protein-coupled receptors. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-018-04342-1\">https://doi.org/10.1038/s41467-018-04342-1</a>","ama":"Morri M, Sanchez-Romero I, Tichy A-M, et al. Optical functionalization of human class A orphan G-protein-coupled receptors. <i>Nature Communications</i>. 2018;9(1). doi:<a href=\"https://doi.org/10.1038/s41467-018-04342-1\">10.1038/s41467-018-04342-1</a>","ieee":"M. Morri <i>et al.</i>, “Optical functionalization of human class A orphan G-protein-coupled receptors,” <i>Nature Communications</i>, vol. 9, no. 1. Springer Nature, 2018.","chicago":"Morri, Maurizio, Inmaculada Sanchez-Romero, Alexandra-Madelaine Tichy, Stephanie Kainrath, Elliot J. Gerrard, Priscila Hirschfeld, Jan Schwarz, and Harald L Janovjak. “Optical Functionalization of Human Class A Orphan G-Protein-Coupled Receptors.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-018-04342-1\">https://doi.org/10.1038/s41467-018-04342-1</a>.","short":"M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).","mla":"Morri, Maurizio, et al. “Optical Functionalization of Human Class A Orphan G-Protein-Coupled Receptors.” <i>Nature Communications</i>, vol. 9, no. 1, 1950, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-018-04342-1\">10.1038/s41467-018-04342-1</a>.","ista":"Morri M, Sanchez-Romero I, Tichy A-M, Kainrath S, Gerrard EJ, Hirschfeld P, Schwarz J, Janovjak HL. 2018. Optical functionalization of human class A orphan G-protein-coupled receptors. Nature Communications. 9(1), 1950."},"year":"2018","publisher":"Springer Nature","file_date_updated":"2020-07-14T12:47:14Z","quality_controlled":"1","ec_funded":1,"title":"Optical functionalization of human class A orphan G-protein-coupled receptors","intvolume":"         9","publication_status":"published","article_processing_charge":"No","date_created":"2019-02-14T10:50:24Z","department":[{"_id":"HaJa"},{"_id":"CaGu"},{"_id":"MiSi"}],"author":[{"id":"4863116E-F248-11E8-B48F-1D18A9856A87","last_name":"Morri","first_name":"Maurizio","full_name":"Morri, Maurizio"},{"id":"3D9C5D30-F248-11E8-B48F-1D18A9856A87","full_name":"Sanchez-Romero, Inmaculada","first_name":"Inmaculada","last_name":"Sanchez-Romero"},{"full_name":"Tichy, Alexandra-Madelaine","last_name":"Tichy","first_name":"Alexandra-Madelaine","id":"29D8BB2C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Kainrath","first_name":"Stephanie","full_name":"Kainrath, Stephanie","id":"32CFBA64-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Elliot J.","last_name":"Gerrard","full_name":"Gerrard, Elliot J."},{"first_name":"Priscila","last_name":"Hirschfeld","full_name":"Hirschfeld, Priscila","id":"435ACB3A-F248-11E8-B48F-1D18A9856A87"},{"id":"346C1EC6-F248-11E8-B48F-1D18A9856A87","full_name":"Schwarz, Jan","last_name":"Schwarz","first_name":"Jan"},{"id":"33BA6C30-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8023-9315","full_name":"Janovjak, Harald L","first_name":"Harald L","last_name":"Janovjak"}],"issue":"1","_id":"5984","scopus_import":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","status":"public","file":[{"date_created":"2019-02-14T10:58:29Z","checksum":"8325fcc194264af4749e662a73bf66b5","file_size":1349914,"date_updated":"2020-07-14T12:47:14Z","content_type":"application/pdf","file_name":"2018_Springer_Morri.pdf","relation":"main_file","access_level":"open_access","file_id":"5985","creator":"kschuh"}],"oa":1,"publication_identifier":{"issn":["2041-1723"]},"date_published":"2018-12-01T00:00:00Z","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"language":[{"iso":"eng"}],"month":"12","article_number":"1950","oa_version":"Published Version","project":[{"grant_number":"303564","name":"Microbial Ion Channels for Synthetic Neurobiology","call_identifier":"FP7","_id":"25548C20-B435-11E9-9278-68D0E5697425"},{"_id":"255A6082-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"W1232-B24","name":"Molecular Drug Targets"}],"publication":"Nature Communications","has_accepted_license":"1"},{"extern":"1","volume":9,"abstract":[{"text":"Pore-forming toxins (PFT) are virulence factors that transform from soluble to membrane-bound states. The Yersinia YaxAB system represents a family of binary α-PFTs with orthologues in human, insect, and plant pathogens, with unknown structures. YaxAB was shown to be cytotoxic and likely involved in pathogenesis, though the molecular basis for its two-component lytic mechanism remains elusive. Here, we present crystal structures of YaxA and YaxB, together with a cryo-electron microscopy map of the YaxAB complex. Our structures reveal a pore predominantly composed of decamers of YaxA–YaxB heterodimers. Both subunits bear membrane-active moieties, but only YaxA is capable of binding to membranes by itself. YaxB can subsequently be recruited to membrane-associated YaxA and induced to present its lytic transmembrane helices. Pore formation can progress by further oligomerization of YaxA–YaxB dimers. Our results allow for a comparison between pore assemblies belonging to the wider ClyA-like family of α-PFTs, highlighting diverse pore architectures.","lang":"eng"}],"day":"04","doi":"10.1038/s41467-018-04139-2","external_id":{"pmid":["29728606"]},"year":"2018","citation":{"ista":"Bräuning B, Bertosin E, Praetorius FM, Ihling C, Schatt A, Adler A, Richter K, Sinz A, Dietz H, Groll M. 2018. Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. Nature Communications. 9, 1806.","mla":"Bräuning, Bastian, et al. “Structure and Mechanism of the Two-Component α-Helical Pore-Forming Toxin YaxAB.” <i>Nature Communications</i>, vol. 9, 1806, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-018-04139-2\">10.1038/s41467-018-04139-2</a>.","short":"B. Bräuning, E. Bertosin, F.M. Praetorius, C. Ihling, A. Schatt, A. Adler, K. Richter, A. Sinz, H. Dietz, M. Groll, Nature Communications 9 (2018).","chicago":"Bräuning, Bastian, Eva Bertosin, Florian M Praetorius, Christian Ihling, Alexandra Schatt, Agnes Adler, Klaus Richter, Andrea Sinz, Hendrik Dietz, and Michael Groll. “Structure and Mechanism of the Two-Component α-Helical Pore-Forming Toxin YaxAB.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-018-04139-2\">https://doi.org/10.1038/s41467-018-04139-2</a>.","ieee":"B. Bräuning <i>et al.</i>, “Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB,” <i>Nature Communications</i>, vol. 9. Springer Nature, 2018.","apa":"Bräuning, B., Bertosin, E., Praetorius, F. M., Ihling, C., Schatt, A., Adler, A., … Groll, M. (2018). Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-018-04139-2\">https://doi.org/10.1038/s41467-018-04139-2</a>","ama":"Bräuning B, Bertosin E, Praetorius FM, et al. Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. <i>Nature Communications</i>. 2018;9. doi:<a href=\"https://doi.org/10.1038/s41467-018-04139-2\">10.1038/s41467-018-04139-2</a>"},"date_updated":"2023-11-07T11:46:12Z","article_type":"original","publisher":"Springer Nature","quality_controlled":"1","intvolume":"         9","title":"Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB","article_processing_charge":"No","date_created":"2023-09-06T12:07:33Z","publication_status":"published","author":[{"full_name":"Bräuning, Bastian","last_name":"Bräuning","first_name":"Bastian"},{"first_name":"Eva","last_name":"Bertosin","full_name":"Bertosin, Eva"},{"id":"dfec9381-4341-11ee-8fd8-faa02bba7d62","full_name":"Praetorius, Florian M","first_name":"Florian M","last_name":"Praetorius"},{"full_name":"Ihling, Christian","last_name":"Ihling","first_name":"Christian"},{"last_name":"Schatt","first_name":"Alexandra","full_name":"Schatt, Alexandra"},{"first_name":"Agnes","last_name":"Adler","full_name":"Adler, Agnes"},{"full_name":"Richter, Klaus","last_name":"Richter","first_name":"Klaus"},{"first_name":"Andrea","last_name":"Sinz","full_name":"Sinz, Andrea"},{"full_name":"Dietz, Hendrik","last_name":"Dietz","first_name":"Hendrik"},{"full_name":"Groll, Michael","last_name":"Groll","first_name":"Michael"}],"scopus_import":"1","pmid":1,"_id":"14284","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","main_file_link":[{"url":"https://doi.org/10.1038/s41467-018-04139-2","open_access":"1"}],"oa":1,"publication_identifier":{"issn":["2041-1723"]},"type":"journal_article","date_published":"2018-05-04T00:00:00Z","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"language":[{"iso":"eng"}],"article_number":"1806","month":"05","oa_version":"Published Version","publication":"Nature Communications"},{"publication":"Nature Communications","oa_version":"Published Version","article_number":"328","month":"08","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry"],"language":[{"iso":"eng"}],"type":"journal_article","date_published":"2017-08-30T00:00:00Z","publication_identifier":{"issn":["2041-1723"]},"oa":1,"main_file_link":[{"url":"https://doi.org/10.1038/s41467-017-00322-z","open_access":"1"}],"user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","status":"public","scopus_import":"1","_id":"11065","pmid":1,"author":[{"first_name":"Abigail","last_name":"Buchwalter","full_name":"Buchwalter, Abigail"},{"full_name":"HETZER, Martin W","orcid":"0000-0002-2111-992X","last_name":"HETZER","first_name":"Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed"}],"date_created":"2022-04-07T07:45:50Z","article_processing_charge":"No","publication_status":"published","intvolume":"         8","title":"Nucleolar expansion and elevated protein translation in premature aging","quality_controlled":"1","publisher":"Springer Nature","article_type":"original","citation":{"ista":"Buchwalter A, Hetzer M. 2017. Nucleolar expansion and elevated protein translation in premature aging. Nature Communications. 8, 328.","short":"A. Buchwalter, M. Hetzer, Nature Communications 8 (2017).","mla":"Buchwalter, Abigail, and Martin Hetzer. “Nucleolar Expansion and Elevated Protein Translation in Premature Aging.” <i>Nature Communications</i>, vol. 8, 328, Springer Nature, 2017, doi:<a href=\"https://doi.org/10.1038/s41467-017-00322-z\">10.1038/s41467-017-00322-z</a>.","ieee":"A. Buchwalter and M. Hetzer, “Nucleolar expansion and elevated protein translation in premature aging,” <i>Nature Communications</i>, vol. 8. Springer Nature, 2017.","chicago":"Buchwalter, Abigail, and Martin Hetzer. “Nucleolar Expansion and Elevated Protein Translation in Premature Aging.” <i>Nature Communications</i>. Springer Nature, 2017. <a href=\"https://doi.org/10.1038/s41467-017-00322-z\">https://doi.org/10.1038/s41467-017-00322-z</a>.","apa":"Buchwalter, A., &#38; Hetzer, M. (2017). Nucleolar expansion and elevated protein translation in premature aging. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-017-00322-z\">https://doi.org/10.1038/s41467-017-00322-z</a>","ama":"Buchwalter A, Hetzer M. Nucleolar expansion and elevated protein translation in premature aging. <i>Nature Communications</i>. 2017;8. doi:<a href=\"https://doi.org/10.1038/s41467-017-00322-z\">10.1038/s41467-017-00322-z</a>"},"year":"2017","date_updated":"2022-07-18T08:33:03Z","external_id":{"pmid":["28855503"]},"day":"30","doi":"10.1038/s41467-017-00322-z","abstract":[{"text":"Premature aging disorders provide an opportunity to study the mechanisms that drive aging. In Hutchinson-Gilford progeria syndrome (HGPS), a mutant form of the nuclear scaffold protein lamin A distorts nuclei and sequesters nuclear proteins. We sought to investigate protein homeostasis in this disease. Here, we report a widespread increase in protein turnover in HGPS-derived cells compared to normal cells. We determine that global protein synthesis is elevated as a consequence of activated nucleoli and enhanced ribosome biogenesis in HGPS-derived fibroblasts. Depleting normal lamin A or inducing mutant lamin A expression are each sufficient to drive nucleolar expansion. We further show that nucleolar size correlates with donor age in primary fibroblasts derived from healthy individuals and that ribosomal RNA production increases with age, indicating that nucleolar size and activity can serve as aging biomarkers. While limiting ribosome biogenesis extends lifespan in several systems, we show that increased ribosome biogenesis and activity are a hallmark of premature aging.","lang":"eng"}],"volume":8,"extern":"1"},{"publication_status":"published","oa_version":"Published Version","article_processing_charge":"No","date_created":"2020-09-18T10:06:01Z","month":"07","title":"Slow conformational exchange and overall rocking motion in ubiquitin protein crystals","article_number":"145","intvolume":"         8","publication":"Nature Communications","_id":"8445","author":[{"full_name":"Kurauskas, Vilius","last_name":"Kurauskas","first_name":"Vilius"},{"last_name":"Izmailov","first_name":"Sergei A.","full_name":"Izmailov, Sergei A."},{"full_name":"Rogacheva, Olga N.","first_name":"Olga N.","last_name":"Rogacheva"},{"first_name":"Audrey","last_name":"Hessel","full_name":"Hessel, Audrey"},{"first_name":"Isabel","last_name":"Ayala","full_name":"Ayala, Isabel"},{"first_name":"Joyce","last_name":"Woodhouse","full_name":"Woodhouse, Joyce"},{"full_name":"Shilova, Anastasya","last_name":"Shilova","first_name":"Anastasya"},{"last_name":"Xue","first_name":"Yi","full_name":"Xue, Yi"},{"full_name":"Yuwen, Tairan","first_name":"Tairan","last_name":"Yuwen"},{"first_name":"Nicolas","last_name":"Coquelle","full_name":"Coquelle, Nicolas"},{"last_name":"Colletier","first_name":"Jacques-Philippe","full_name":"Colletier, Jacques-Philippe"},{"full_name":"Skrynnikov, Nikolai R.","first_name":"Nikolai R.","last_name":"Skrynnikov"},{"id":"7B541462-FAF6-11E9-A490-E8DFE5697425","orcid":"0000-0002-9350-7606","full_name":"Schanda, Paul","first_name":"Paul","last_name":"Schanda"}],"publisher":"Springer Nature","article_type":"original","quality_controlled":"1","language":[{"iso":"eng"}],"doi":"10.1038/s41467-017-00165-8","day":"27","publication_identifier":{"issn":["2041-1723"]},"abstract":[{"lang":"eng","text":"Proteins perform their functions in solution but their structures are most frequently studied inside crystals. Here we probe how the crystal packing alters microsecond dynamics, using solid-state NMR measurements and multi-microsecond MD simulations of different crystal forms of ubiquitin. In particular, near-rotary-resonance relaxation dispersion (NERRD) experiments probe angular backbone motion, while Bloch–McConnell relaxation dispersion data report on fluctuations of the local electronic environment. These experiments and simulations reveal that the packing of the protein can significantly alter the thermodynamics and kinetics of local conformational exchange. Moreover, we report small-amplitude reorientational motion of protein molecules in the crystal lattice with an ~3–5° amplitude on a tens-of-microseconds time scale in one of the crystals, but not in others. An intriguing possibility arises that overall motion is to some extent coupled to local dynamics. Our study highlights the importance of considering the packing when analyzing dynamics of crystalline proteins."}],"date_updated":"2021-01-12T08:19:19Z","citation":{"ieee":"V. Kurauskas <i>et al.</i>, “Slow conformational exchange and overall rocking motion in ubiquitin protein crystals,” <i>Nature Communications</i>, vol. 8. Springer Nature, 2017.","chicago":"Kurauskas, Vilius, Sergei A. Izmailov, Olga N. Rogacheva, Audrey Hessel, Isabel Ayala, Joyce Woodhouse, Anastasya Shilova, et al. “Slow Conformational Exchange and Overall Rocking Motion in Ubiquitin Protein Crystals.” <i>Nature Communications</i>. Springer Nature, 2017. <a href=\"https://doi.org/10.1038/s41467-017-00165-8\">https://doi.org/10.1038/s41467-017-00165-8</a>.","ama":"Kurauskas V, Izmailov SA, Rogacheva ON, et al. Slow conformational exchange and overall rocking motion in ubiquitin protein crystals. <i>Nature Communications</i>. 2017;8. doi:<a href=\"https://doi.org/10.1038/s41467-017-00165-8\">10.1038/s41467-017-00165-8</a>","apa":"Kurauskas, V., Izmailov, S. A., Rogacheva, O. N., Hessel, A., Ayala, I., Woodhouse, J., … Schanda, P. (2017). Slow conformational exchange and overall rocking motion in ubiquitin protein crystals. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-017-00165-8\">https://doi.org/10.1038/s41467-017-00165-8</a>","ista":"Kurauskas V, Izmailov SA, Rogacheva ON, Hessel A, Ayala I, Woodhouse J, Shilova A, Xue Y, Yuwen T, Coquelle N, Colletier J-P, Skrynnikov NR, Schanda P. 2017. Slow conformational exchange and overall rocking motion in ubiquitin protein crystals. Nature Communications. 8, 145.","mla":"Kurauskas, Vilius, et al. “Slow Conformational Exchange and Overall Rocking Motion in Ubiquitin Protein Crystals.” <i>Nature Communications</i>, vol. 8, 145, Springer Nature, 2017, doi:<a href=\"https://doi.org/10.1038/s41467-017-00165-8\">10.1038/s41467-017-00165-8</a>.","short":"V. Kurauskas, S.A. Izmailov, O.N. Rogacheva, A. Hessel, I. Ayala, J. Woodhouse, A. Shilova, Y. Xue, T. Yuwen, N. Coquelle, J.-P. Colletier, N.R. Skrynnikov, P. Schanda, Nature Communications 8 (2017)."},"year":"2017","date_published":"2017-07-27T00:00:00Z","type":"journal_article","volume":8,"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public"},{"publisher":"Springer Nature","article_type":"original","quality_controlled":"1","file_date_updated":"2020-07-14T12:47:48Z","article_processing_charge":"No","date_created":"2019-11-19T13:11:55Z","publication_status":"published","intvolume":"         8","title":"Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates","_id":"7064","issue":"1","author":[{"id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","last_name":"Modic","first_name":"Kimberly A","full_name":"Modic, Kimberly A","orcid":"0000-0001-9760-3147"},{"full_name":"Ramshaw, B. J.","first_name":"B. J.","last_name":"Ramshaw"},{"first_name":"J. B.","last_name":"Betts","full_name":"Betts, J. B."},{"full_name":"Breznay, Nicholas P.","first_name":"Nicholas P.","last_name":"Breznay"},{"last_name":"Analytis","first_name":"James G.","full_name":"Analytis, James G."},{"full_name":"McDonald, Ross D.","first_name":"Ross D.","last_name":"McDonald"},{"last_name":"Shekhter","first_name":"Arkady","full_name":"Shekhter, Arkady"}],"volume":8,"ddc":["530"],"extern":"1","day":"01","doi":"10.1038/s41467-017-00264-6","abstract":[{"lang":"eng","text":"The complex antiferromagnetic orders observed in the honeycomb iridates are a double-edged sword in the search for a quantum spin-liquid: both attesting that the magnetic interactions provide many of the necessary ingredients, while simultaneously impeding access. Focus has naturally been drawn to the unusual magnetic orders that hint at the underlying spin correlations. However, the study of any particular broken symmetry state generally provides little clue about the possibility of other nearby ground states. Here we use magnetic fields approaching 100 Tesla to reveal the extent of the spin correlations in γ-lithium iridate. We find that a small component of field along the magnetic easy-axis melts long-range order, revealing a bistable, strongly correlated spin state. Far from the usual destruction of antiferromagnetism via spin polarization, the high-field state possesses only a small fraction of the total iridium moment, without evidence for long-range order up to the highest attainable magnetic fields."}],"citation":{"ama":"Modic KA, Ramshaw BJ, Betts JB, et al. Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates. <i>Nature Communications</i>. 2017;8(1). doi:<a href=\"https://doi.org/10.1038/s41467-017-00264-6\">10.1038/s41467-017-00264-6</a>","apa":"Modic, K. A., Ramshaw, B. J., Betts, J. B., Breznay, N. P., Analytis, J. G., McDonald, R. D., &#38; Shekhter, A. (2017). Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-017-00264-6\">https://doi.org/10.1038/s41467-017-00264-6</a>","chicago":"Modic, Kimberly A, B. J. Ramshaw, J. B. Betts, Nicholas P. Breznay, James G. Analytis, Ross D. McDonald, and Arkady Shekhter. “Robust Spin Correlations at High Magnetic Fields in the Harmonic Honeycomb Iridates.” <i>Nature Communications</i>. Springer Nature, 2017. <a href=\"https://doi.org/10.1038/s41467-017-00264-6\">https://doi.org/10.1038/s41467-017-00264-6</a>.","ieee":"K. A. Modic <i>et al.</i>, “Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates,” <i>Nature Communications</i>, vol. 8, no. 1. Springer Nature, 2017.","short":"K.A. Modic, B.J. Ramshaw, J.B. Betts, N.P. Breznay, J.G. Analytis, R.D. McDonald, A. Shekhter, Nature Communications 8 (2017).","mla":"Modic, Kimberly A., et al. “Robust Spin Correlations at High Magnetic Fields in the Harmonic Honeycomb Iridates.” <i>Nature Communications</i>, vol. 8, no. 1, 180, Springer Nature, 2017, doi:<a href=\"https://doi.org/10.1038/s41467-017-00264-6\">10.1038/s41467-017-00264-6</a>.","ista":"Modic KA, Ramshaw BJ, Betts JB, Breznay NP, Analytis JG, McDonald RD, Shekhter A. 2017. Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates. Nature Communications. 8(1), 180."},"year":"2017","date_updated":"2021-01-12T08:11:39Z","language":[{"iso":"eng"}],"oa_version":"Published Version","article_number":"180","month":"08","has_accepted_license":"1","publication":"Nature Communications","file":[{"date_created":"2019-11-20T14:12:54Z","file_size":1242958,"checksum":"57fcd59d2f274b6b16cc89ea03cfd440","date_updated":"2020-07-14T12:47:48Z","file_name":"2017_NatureComm_Modic.pdf","content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_id":"7091","creator":"cziletti"}],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["2041-1723"]},"oa":1,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"type":"journal_article","date_published":"2017-08-01T00:00:00Z"},{"month":"12","article_number":"13874","oa_version":"Published Version","publication":"Nature Communications","language":[{"iso":"eng"}],"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry"],"oa":1,"publication_identifier":{"issn":["2041-1723"]},"date_published":"2016-12-22T00:00:00Z","type":"journal_article","related_material":{"link":[{"relation":"erratum","url":"https://doi.org/10.1038/ncomms16030"}]},"user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/ncomms13874"}],"title":"p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis","intvolume":"         7","publication_status":"published","date_created":"2022-04-07T07:48:34Z","article_processing_charge":"No","author":[{"full_name":"van de Ven, Robert A.H.","last_name":"van de Ven","first_name":"Robert A.H."},{"last_name":"de Groot","first_name":"Jolien S.","full_name":"de Groot, Jolien S."},{"last_name":"Park","first_name":"Danielle","full_name":"Park, Danielle"},{"first_name":"Robert","last_name":"van Domselaar","full_name":"van Domselaar, Robert"},{"full_name":"de Jong, Danielle","last_name":"de Jong","first_name":"Danielle"},{"full_name":"Szuhai, Karoly","first_name":"Karoly","last_name":"Szuhai"},{"last_name":"van der Wall","first_name":"Elsken","full_name":"van der Wall, Elsken"},{"first_name":"Oscar M.","last_name":"Rueda","full_name":"Rueda, Oscar M."},{"full_name":"Ali, H. Raza","first_name":"H. Raza","last_name":"Ali"},{"last_name":"Caldas","first_name":"Carlos","full_name":"Caldas, Carlos"},{"full_name":"van Diest, Paul J.","first_name":"Paul J.","last_name":"van Diest"},{"last_name":"HETZER","first_name":"Martin W","full_name":"HETZER, Martin W","orcid":"0000-0002-2111-992X","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed"},{"full_name":"Sahai, Erik","last_name":"Sahai","first_name":"Erik"},{"last_name":"Derksen","first_name":"Patrick W.B.","full_name":"Derksen, Patrick W.B."}],"pmid":1,"_id":"11072","scopus_import":"1","article_type":"original","publisher":"Springer Nature","quality_controlled":"1","abstract":[{"lang":"eng","text":"Spatiotemporal activation of RhoA and actomyosin contraction underpins cellular adhesion and division. Loss of cell–cell adhesion and chromosomal instability are cardinal events that drive tumour progression. Here, we show that p120-catenin (p120) not only controls cell–cell adhesion, but also acts as a critical regulator of cytokinesis. We find that p120 regulates actomyosin contractility through concomitant binding to RhoA and the centralspindlin component MKLP1, independent of cadherin association. In anaphase, p120 is enriched at the cleavage furrow where it binds MKLP1 to spatially control RhoA GTPase cycling. Binding of p120 to MKLP1 during cytokinesis depends on the N-terminal coiled-coil domain of p120 isoform 1A. Importantly, clinical data show that loss of p120 expression is a common event in breast cancer that strongly correlates with multinucleation and adverse patient survival. In summary, our study identifies p120 loss as a driver event of chromosomal instability in cancer.\r\n"}],"doi":"10.1038/ncomms13874","day":"22","external_id":{"pmid":["28004812"]},"date_updated":"2022-07-18T08:34:32Z","year":"2016","citation":{"apa":"van de Ven, R. A. H., de Groot, J. S., Park, D., van Domselaar, R., de Jong, D., Szuhai, K., … Derksen, P. W. B. (2016). p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/ncomms13874\">https://doi.org/10.1038/ncomms13874</a>","ama":"van de Ven RAH, de Groot JS, Park D, et al. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. <i>Nature Communications</i>. 2016;7. doi:<a href=\"https://doi.org/10.1038/ncomms13874\">10.1038/ncomms13874</a>","chicago":"Ven, Robert A.H. van de, Jolien S. de Groot, Danielle Park, Robert van Domselaar, Danielle de Jong, Karoly Szuhai, Elsken van der Wall, et al. “P120-Catenin Prevents Multinucleation through Control of MKLP1-Dependent RhoA Activity during Cytokinesis.” <i>Nature Communications</i>. Springer Nature, 2016. <a href=\"https://doi.org/10.1038/ncomms13874\">https://doi.org/10.1038/ncomms13874</a>.","ieee":"R. A. H. van de Ven <i>et al.</i>, “p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis,” <i>Nature Communications</i>, vol. 7. Springer Nature, 2016.","mla":"van de Ven, Robert A. H., et al. “P120-Catenin Prevents Multinucleation through Control of MKLP1-Dependent RhoA Activity during Cytokinesis.” <i>Nature Communications</i>, vol. 7, 13874, Springer Nature, 2016, doi:<a href=\"https://doi.org/10.1038/ncomms13874\">10.1038/ncomms13874</a>.","short":"R.A.H. van de Ven, J.S. de Groot, D. Park, R. van Domselaar, D. de Jong, K. Szuhai, E. van der Wall, O.M. Rueda, H.R. Ali, C. Caldas, P.J. van Diest, M. Hetzer, E. Sahai, P.W.B. Derksen, Nature Communications 7 (2016).","ista":"van de Ven RAH, de Groot JS, Park D, van Domselaar R, de Jong D, Szuhai K, van der Wall E, Rueda OM, Ali HR, Caldas C, van Diest PJ, Hetzer M, Sahai E, Derksen PWB. 2016. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nature Communications. 7, 13874."},"extern":"1","volume":7},{"extern":"1","ddc":["530"],"volume":7,"date_updated":"2021-01-12T08:11:40Z","year":"2016","citation":{"chicago":"Moll, Philip J. W., Andrew C. Potter, Nityan L. Nair, B. J. Ramshaw, Kimberly A Modic, Scott Riggs, Bin Zeng, et al. “Magnetic Torque Anomaly in the Quantum Limit of Weyl Semimetals.” <i>Nature Communications</i>. Springer Nature, 2016. <a href=\"https://doi.org/10.1038/ncomms12492\">https://doi.org/10.1038/ncomms12492</a>.","ieee":"P. J. W. Moll <i>et al.</i>, “Magnetic torque anomaly in the quantum limit of Weyl semimetals,” <i>Nature Communications</i>, vol. 7. Springer Nature, 2016.","ama":"Moll PJW, Potter AC, Nair NL, et al. Magnetic torque anomaly in the quantum limit of Weyl semimetals. <i>Nature Communications</i>. 2016;7. doi:<a href=\"https://doi.org/10.1038/ncomms12492\">10.1038/ncomms12492</a>","apa":"Moll, P. J. W., Potter, A. C., Nair, N. L., Ramshaw, B. J., Modic, K. A., Riggs, S., … Analytis, J. G. (2016). Magnetic torque anomaly in the quantum limit of Weyl semimetals. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/ncomms12492\">https://doi.org/10.1038/ncomms12492</a>","ista":"Moll PJW, Potter AC, Nair NL, Ramshaw BJ, Modic KA, Riggs S, Zeng B, Ghimire NJ, Bauer ED, Kealhofer R, Ronning F, Analytis JG. 2016. Magnetic torque anomaly in the quantum limit of Weyl semimetals. Nature Communications. 7, 12492.","short":"P.J.W. Moll, A.C. Potter, N.L. Nair, B.J. Ramshaw, K.A. Modic, S. Riggs, B. Zeng, N.J. Ghimire, E.D. Bauer, R. Kealhofer, F. Ronning, J.G. Analytis, Nature Communications 7 (2016).","mla":"Moll, Philip J. W., et al. “Magnetic Torque Anomaly in the Quantum Limit of Weyl Semimetals.” <i>Nature Communications</i>, vol. 7, 12492, Springer Nature, 2016, doi:<a href=\"https://doi.org/10.1038/ncomms12492\">10.1038/ncomms12492</a>."},"abstract":[{"lang":"eng","text":"Electrons in materials with linear dispersion behave as massless Weyl- or Dirac-quasiparticles, and continue to intrigue due to their close resemblance to elusive ultra-relativistic particles as well as their potential for future electronics. Yet the experimental signatures of Weyl-fermions are often subtle and indirect, in particular if they coexist with conventional, massive quasiparticles. Here we show a pronounced anomaly in the magnetic torque of the Weyl semimetal NbAs upon entering the quantum limit state in high magnetic fields. The torque changes sign in the quantum limit, signalling a reversal of the magnetic anisotropy that can be directly attributed to the topological nature of the Weyl electrons. Our results establish that anomalous quantum limit torque measurements provide a direct experimental method to identify and distinguish Weyl and Dirac systems."}],"doi":"10.1038/ncomms12492","day":"22","file_date_updated":"2020-07-14T12:47:48Z","quality_controlled":"1","article_type":"original","publisher":"Springer Nature","author":[{"full_name":"Moll, Philip J. W.","first_name":"Philip J. W.","last_name":"Moll"},{"full_name":"Potter, Andrew C.","last_name":"Potter","first_name":"Andrew C."},{"full_name":"Nair, Nityan L.","first_name":"Nityan L.","last_name":"Nair"},{"first_name":"B. J.","last_name":"Ramshaw","full_name":"Ramshaw, B. J."},{"last_name":"Modic","first_name":"Kimberly A","full_name":"Modic, Kimberly A","orcid":"0000-0001-9760-3147","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425"},{"last_name":"Riggs","first_name":"Scott","full_name":"Riggs, Scott"},{"full_name":"Zeng, Bin","first_name":"Bin","last_name":"Zeng"},{"last_name":"Ghimire","first_name":"Nirmal J.","full_name":"Ghimire, Nirmal J."},{"first_name":"Eric D.","last_name":"Bauer","full_name":"Bauer, Eric D."},{"full_name":"Kealhofer, Robert","first_name":"Robert","last_name":"Kealhofer"},{"last_name":"Ronning","first_name":"Filip","full_name":"Ronning, Filip"},{"full_name":"Analytis, James G.","last_name":"Analytis","first_name":"James G."}],"_id":"7068","title":"Magnetic torque anomaly in the quantum limit of Weyl semimetals","intvolume":"         7","publication_status":"published","article_processing_charge":"No","date_created":"2019-11-19T13:20:53Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","file":[{"relation":"main_file","access_level":"open_access","creator":"dernst","file_id":"7114","file_size":663911,"checksum":"e3272ed18d22187406b30be48a56e7b2","date_created":"2019-11-26T12:52:19Z","file_name":"2016_NatureComm_Moll.pdf","content_type":"application/pdf","date_updated":"2020-07-14T12:47:48Z"}],"date_published":"2016-08-22T00:00:00Z","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"publication_identifier":{"issn":["2041-1723"]},"language":[{"iso":"eng"}],"publication":"Nature Communications","has_accepted_license":"1","month":"08","article_number":"12492","oa_version":"Published Version"}]