---
_id: '9119'
abstract:
- lang: eng
  text: 'We present DILS, a deployable statistical analysis platform for conducting
    demographic inferences with linked selection from population genomic data using
    an Approximate Bayesian Computation framework. DILS takes as input single‐population
    or two‐population data sets (multilocus fasta sequences) and performs three types
    of analyses in a hierarchical manner, identifying: (a) the best demographic model
    to study the importance of gene flow and population size change on the genetic
    patterns of polymorphism and divergence, (b) the best genomic model to determine
    whether the effective size Ne and migration rate N, m are heterogeneously distributed
    along the genome (implying linked selection) and (c) loci in genomic regions most
    associated with barriers to gene flow. Also available via a Web interface, an
    objective of DILS is to facilitate collaborative research in speciation genomics.
    Here, we show the performance and limitations of DILS by using simulations and
    finally apply the method to published data on a divergence continuum composed
    by 28 pairs of Mytilus mussel populations/species.'
article_processing_charge: No
article_type: original
author:
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: Iva
  full_name: Popovic, Iva
  last_name: Popovic
- first_name: Clément
  full_name: Mazoyer, Clément
  last_name: Mazoyer
- first_name: Bruno
  full_name: Spataro, Bruno
  last_name: Spataro
- first_name: Stéphane
  full_name: Delmotte, Stéphane
  last_name: Delmotte
- first_name: Jonathan
  full_name: Romiguier, Jonathan
  last_name: Romiguier
- first_name: Étienne
  full_name: Loire, Étienne
  last_name: Loire
- first_name: Alexis
  full_name: Simon, Alexis
  last_name: Simon
- first_name: Nicolas
  full_name: Galtier, Nicolas
  last_name: Galtier
- first_name: Laurent
  full_name: Duret, Laurent
  last_name: Duret
- first_name: Nicolas
  full_name: Bierne, Nicolas
  last_name: Bierne
- first_name: Xavier
  full_name: Vekemans, Xavier
  last_name: Vekemans
- first_name: Camille
  full_name: Roux, Camille
  last_name: Roux
citation:
  ama: 'Fraisse C, Popovic I, Mazoyer C, et al. DILS: Demographic inferences with
    linked selection by using ABC. <i>Molecular Ecology Resources</i>. 2021;21:2629-2644.
    doi:<a href="https://doi.org/10.1111/1755-0998.13323">10.1111/1755-0998.13323</a>'
  apa: 'Fraisse, C., Popovic, I., Mazoyer, C., Spataro, B., Delmotte, S., Romiguier,
    J., … Roux, C. (2021). DILS: Demographic inferences with linked selection by using
    ABC. <i>Molecular Ecology Resources</i>. Wiley. <a href="https://doi.org/10.1111/1755-0998.13323">https://doi.org/10.1111/1755-0998.13323</a>'
  chicago: 'Fraisse, Christelle, Iva Popovic, Clément Mazoyer, Bruno Spataro, Stéphane
    Delmotte, Jonathan Romiguier, Étienne Loire, et al. “DILS: Demographic Inferences
    with Linked Selection by Using ABC.” <i>Molecular Ecology Resources</i>. Wiley,
    2021. <a href="https://doi.org/10.1111/1755-0998.13323">https://doi.org/10.1111/1755-0998.13323</a>.'
  ieee: 'C. Fraisse <i>et al.</i>, “DILS: Demographic inferences with linked selection
    by using ABC,” <i>Molecular Ecology Resources</i>, vol. 21. Wiley, pp. 2629–2644,
    2021.'
  ista: 'Fraisse C, Popovic I, Mazoyer C, Spataro B, Delmotte S, Romiguier J, Loire
    É, Simon A, Galtier N, Duret L, Bierne N, Vekemans X, Roux C. 2021. DILS: Demographic
    inferences with linked selection by using ABC. Molecular Ecology Resources. 21,
    2629–2644.'
  mla: 'Fraisse, Christelle, et al. “DILS: Demographic Inferences with Linked Selection
    by Using ABC.” <i>Molecular Ecology Resources</i>, vol. 21, Wiley, 2021, pp. 2629–44,
    doi:<a href="https://doi.org/10.1111/1755-0998.13323">10.1111/1755-0998.13323</a>.'
  short: C. Fraisse, I. Popovic, C. Mazoyer, B. Spataro, S. Delmotte, J. Romiguier,
    É. Loire, A. Simon, N. Galtier, L. Duret, N. Bierne, X. Vekemans, C. Roux, Molecular
    Ecology Resources 21 (2021) 2629–2644.
date_created: 2021-02-14T23:01:14Z
date_published: 2021-01-15T00:00:00Z
date_updated: 2023-08-07T13:45:18Z
day: '15'
department:
- _id: NiBa
doi: 10.1111/1755-0998.13323
external_id:
  isi:
  - '000614183100001'
intvolume: '        21'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.biorxiv.org/content/10.1101/2020.06.15.151597v2
month: '01'
oa: 1
oa_version: Preprint
page: 2629-2644
publication: Molecular Ecology Resources
publication_identifier:
  eissn:
  - '17550998'
  issn:
  - 1755098X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'DILS: Demographic inferences with linked selection by using ABC'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 21
year: '2021'
...