---
_id: '13097'
abstract:
- lang: eng
  text: 'Vertebrate movement is orchestrated by spinal inter- and motor neurons that,
    together with sensory and cognitive input, produce dynamic motor behaviors. These
    behaviors vary from the simple undulatory swimming of fish and larval aquatic
    species to the highly coordinated running, reaching and grasping of mice, humans
    and other mammals. This variation raises the fundamental question of how spinal
    circuits have changed in register with motor behavior. In simple, undulatory fish,
    exemplified by the lamprey, two broad classes of interneurons shape motor neuron
    output: ipsilateral-projecting excitatory neurons, and commissural-projecting
    inhibitory neurons. An additional class of ipsilateral inhibitory neurons is required
    to generate escape swim behavior in larval zebrafish and tadpoles. In limbed vertebrates,
    a more complex spinal neuron composition is observed. In this review, we provide
    evidence that movement elaboration correlates with an increase and specialization
    of these three basic interneuron types into molecularly, anatomically, and functionally
    distinct subpopulations. We summarize recent work linking neuron types to movement-pattern
    generation across fish, amphibians, reptiles, birds and mammals.'
acknowledgement: 'This work was supported by the ERC Starting grant, ERC-2021-STG
  #101041551.'
article_number: '1146449'
article_processing_charge: Yes
article_type: original
author:
- first_name: Alexia C
  full_name: Wilson, Alexia C
  id: 5230e794-15b2-11ec-abd3-e2d5335ebd1d
  last_name: Wilson
- first_name: Lora Beatrice Jaeger
  full_name: Sweeney, Lora Beatrice Jaeger
  id: 56BE8254-C4F0-11E9-8E45-0B23E6697425
  last_name: Sweeney
  orcid: 0000-0001-9242-5601
citation:
  ama: 'Wilson AC, Sweeney LB. Spinal cords: Symphonies of interneurons across species.
    <i>Frontiers in Neural Circuits</i>. 2023;17. doi:<a href="https://doi.org/10.3389/fncir.2023.1146449">10.3389/fncir.2023.1146449</a>'
  apa: 'Wilson, A. C., &#38; Sweeney, L. B. (2023). Spinal cords: Symphonies of interneurons
    across species. <i>Frontiers in Neural Circuits</i>. Frontiers. <a href="https://doi.org/10.3389/fncir.2023.1146449">https://doi.org/10.3389/fncir.2023.1146449</a>'
  chicago: 'Wilson, Alexia C, and Lora B. Sweeney. “Spinal Cords: Symphonies of Interneurons
    across Species.” <i>Frontiers in Neural Circuits</i>. Frontiers, 2023. <a href="https://doi.org/10.3389/fncir.2023.1146449">https://doi.org/10.3389/fncir.2023.1146449</a>.'
  ieee: 'A. C. Wilson and L. B. Sweeney, “Spinal cords: Symphonies of interneurons
    across species,” <i>Frontiers in Neural Circuits</i>, vol. 17. Frontiers, 2023.'
  ista: 'Wilson AC, Sweeney LB. 2023. Spinal cords: Symphonies of interneurons across
    species. Frontiers in Neural Circuits. 17, 1146449.'
  mla: 'Wilson, Alexia C., and Lora B. Sweeney. “Spinal Cords: Symphonies of Interneurons
    across Species.” <i>Frontiers in Neural Circuits</i>, vol. 17, 1146449, Frontiers,
    2023, doi:<a href="https://doi.org/10.3389/fncir.2023.1146449">10.3389/fncir.2023.1146449</a>.'
  short: A.C. Wilson, L.B. Sweeney, Frontiers in Neural Circuits 17 (2023).
date_created: 2023-05-28T22:01:04Z
date_published: 2023-04-26T00:00:00Z
date_updated: 2024-01-31T10:15:53Z
day: '26'
ddc:
- '570'
department:
- _id: LoSw
doi: 10.3389/fncir.2023.1146449
external_id:
  isi:
  - '000984606200001'
  pmid:
  - '37180760'
file:
- access_level: open_access
  checksum: 7efd06de284a28e91e97127611a9c3fd
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-03T13:33:21Z
  date_updated: 2024-01-03T13:33:21Z
  file_id: '14729'
  file_name: 2023_FrontiersNeuralCircuits_Wilson.pdf
  file_size: 6667157
  relation: main_file
  success: 1
file_date_updated: 2024-01-03T13:33:21Z
has_accepted_license: '1'
intvolume: '        17'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: ebb66355-77a9-11ec-83b8-b8ac210a4dae
  grant_number: '101041551'
  name: Development and Evolution of Tetrapod Motor Circuits
publication: Frontiers in Neural Circuits
publication_identifier:
  issn:
  - 1662-5110
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Spinal cords: Symphonies of interneurons across species'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2023'
...
---
_id: '12149'
abstract:
- lang: eng
  text: Editorial on the Research Topic
acknowledgement: This work was supported by a DFG grant ZA990/1 to DZ. This work was
  supported by the MSCA EU proposal 841301 - DREAM, European Commission; Horizon 2020
  - Research and Innovation Framework Programme to JFRV.
article_number: '1028154'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Giuditta
  full_name: Gambino, Giuditta
  last_name: Gambino
- first_name: Rebecca
  full_name: Bhik-Ghanie, Rebecca
  last_name: Bhik-Ghanie
- first_name: Giuseppe
  full_name: Giglia, Giuseppe
  last_name: Giglia
- first_name: M. Victoria
  full_name: Puig, M. Victoria
  last_name: Puig
- first_name: Juan F
  full_name: Ramirez Villegas, Juan F
  id: 44B06F76-F248-11E8-B48F-1D18A9856A87
  last_name: Ramirez Villegas
- first_name: Daniel
  full_name: Zaldivar, Daniel
  last_name: Zaldivar
citation:
  ama: 'Gambino G, Bhik-Ghanie R, Giglia G, Puig MV, Ramirez Villegas JF, Zaldivar
    D. Editorial: Neuromodulatory ascending systems: Their influence at the microscopic
    and macroscopic levels. <i>Frontiers in Neural Circuits</i>. 2022;16. doi:<a href="https://doi.org/10.3389/fncir.2022.1028154">10.3389/fncir.2022.1028154</a>'
  apa: 'Gambino, G., Bhik-Ghanie, R., Giglia, G., Puig, M. V., Ramirez Villegas, J.
    F., &#38; Zaldivar, D. (2022). Editorial: Neuromodulatory ascending systems: Their
    influence at the microscopic and macroscopic levels. <i>Frontiers in Neural Circuits</i>.
    Frontiers Media. <a href="https://doi.org/10.3389/fncir.2022.1028154">https://doi.org/10.3389/fncir.2022.1028154</a>'
  chicago: 'Gambino, Giuditta, Rebecca Bhik-Ghanie, Giuseppe Giglia, M. Victoria Puig,
    Juan F Ramirez Villegas, and Daniel Zaldivar. “Editorial: Neuromodulatory Ascending
    Systems: Their Influence at the Microscopic and Macroscopic Levels.” <i>Frontiers
    in Neural Circuits</i>. Frontiers Media, 2022. <a href="https://doi.org/10.3389/fncir.2022.1028154">https://doi.org/10.3389/fncir.2022.1028154</a>.'
  ieee: 'G. Gambino, R. Bhik-Ghanie, G. Giglia, M. V. Puig, J. F. Ramirez Villegas,
    and D. Zaldivar, “Editorial: Neuromodulatory ascending systems: Their influence
    at the microscopic and macroscopic levels,” <i>Frontiers in Neural Circuits</i>,
    vol. 16. Frontiers Media, 2022.'
  ista: 'Gambino G, Bhik-Ghanie R, Giglia G, Puig MV, Ramirez Villegas JF, Zaldivar
    D. 2022. Editorial: Neuromodulatory ascending systems: Their influence at the
    microscopic and macroscopic levels. Frontiers in Neural Circuits. 16, 1028154.'
  mla: 'Gambino, Giuditta, et al. “Editorial: Neuromodulatory Ascending Systems: Their
    Influence at the Microscopic and Macroscopic Levels.” <i>Frontiers in Neural Circuits</i>,
    vol. 16, 1028154, Frontiers Media, 2022, doi:<a href="https://doi.org/10.3389/fncir.2022.1028154">10.3389/fncir.2022.1028154</a>.'
  short: G. Gambino, R. Bhik-Ghanie, G. Giglia, M.V. Puig, J.F. Ramirez Villegas,
    D. Zaldivar, Frontiers in Neural Circuits 16 (2022).
date_created: 2023-01-12T12:07:39Z
date_published: 2022-10-26T00:00:00Z
date_updated: 2023-08-04T09:01:06Z
day: '26'
ddc:
- '570'
department:
- _id: JoCs
doi: 10.3389/fncir.2022.1028154
ec_funded: 1
external_id:
  isi:
  - '000886671400001'
file:
- access_level: open_access
  checksum: 457aa00e1800847abb340853058531de
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-24T10:10:43Z
  date_updated: 2023-01-24T10:10:43Z
  file_id: '12357'
  file_name: 2022_FrontiersNeuralCircuits_Gambino.pdf
  file_size: 110031
  relation: main_file
  success: 1
file_date_updated: 2023-01-24T10:10:43Z
has_accepted_license: '1'
intvolume: '        16'
isi: 1
keyword:
- Cellular and Molecular Neuroscience
- Cognitive Neuroscience
- Sensory Systems
- Neuroscience (miscellaneous)
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 26BAE2E4-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '841301'
  name: 'The Brainstem-Hippocampus Network Uncovered: Dynamics, Reactivation and Memory
    Consolidation'
publication: Frontiers in Neural Circuits
publication_identifier:
  issn:
  - 1662-5110
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Editorial: Neuromodulatory ascending systems: Their influence at the microscopic
  and macroscopic levels'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 16
year: '2022'
...