---
_id: '9332'
abstract:
- lang: eng
  text: Lateral root (LR) formation is an example of a plant post-embryonic organogenesis
    event. LRs are issued from non-dividing cells entering consecutive steps of formative
    divisions, proliferation and elongation. The chromatin remodeling protein PICKLE
    (PKL) negatively regulates auxin-mediated LR formation through a mechanism that
    is not yet known. Here we show that PKL interacts with RETINOBLASTOMA-RELATED
    1 (RBR1) to repress the LATERAL ORGAN BOUNDARIES-DOMAIN 16 (LBD16) promoter activity.
    Since LBD16 function is required for the formative division of LR founder cells,
    repression mediated by the PKL–RBR1 complex negatively regulates formative division
    and LR formation. Inhibition of LR formation by PKL–RBR1 is counteracted by auxin,
    indicating that, in addition to auxin-mediated transcriptional responses, the
    fine-tuned process of LR formation is also controlled at the chromatin level in
    an auxin-signaling dependent manner.
acknowledgement: "This research was supported by a postdoctoral fellowship of the
  Carl Tryggers Foundation (to K.Ö.) and by grants from Vetenskapsrådet (Nr.: 621-2004-2921
  to L.B.) and VINNOVA (to L.B. and S.R.).\r\nWe thank Frederic Berger, Hidehiro Fukaki,
  Malcolm Bennett, Claudia Köhler, Jiri Friml for providing pRBR1::RBR1-RFP, ssl2-1,
  slr-1, pPKL::PKL-GFP seeds and the DR5 expressing vector, respectively. Authors
  are grateful to Hayashi Kenichiro for providing the auxinol compound and to Rishi
  Bhalerao for stimulating discussions. The technical help of Adeline Rigal and Thomas
  Vain with the auxinol experiments is much appreciated."
article_number: '3862'
article_processing_charge: No
article_type: original
author:
- first_name: Krisztina
  full_name: Ötvös, Krisztina
  id: 29B901B0-F248-11E8-B48F-1D18A9856A87
  last_name: Ötvös
  orcid: 0000-0002-5503-4983
- first_name: Pál
  full_name: Miskolczi, Pál
  last_name: Miskolczi
- first_name: Peter
  full_name: Marhavý, Peter
  id: 3F45B078-F248-11E8-B48F-1D18A9856A87
  last_name: Marhavý
  orcid: 0000-0001-5227-5741
- first_name: Alfredo
  full_name: Cruz-Ramírez, Alfredo
  last_name: Cruz-Ramírez
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Stéphanie
  full_name: Robert, Stéphanie
  last_name: Robert
- first_name: László
  full_name: Bakó, László
  last_name: Bakó
citation:
  ama: Ötvös K, Miskolczi P, Marhavý P, et al. Pickle recruits retinoblastoma related
    1 to control lateral root formation in arabidopsis. <i>International Journal of
    Molecular Sciences</i>. 2021;22(8). doi:<a href="https://doi.org/10.3390/ijms22083862">10.3390/ijms22083862</a>
  apa: Ötvös, K., Miskolczi, P., Marhavý, P., Cruz-Ramírez, A., Benková, E., Robert,
    S., &#38; Bakó, L. (2021). Pickle recruits retinoblastoma related 1 to control
    lateral root formation in arabidopsis. <i>International Journal of Molecular Sciences</i>.
    MDPI. <a href="https://doi.org/10.3390/ijms22083862">https://doi.org/10.3390/ijms22083862</a>
  chicago: Ötvös, Krisztina, Pál Miskolczi, Peter Marhavý, Alfredo Cruz-Ramírez, Eva
    Benková, Stéphanie Robert, and László Bakó. “Pickle Recruits Retinoblastoma Related
    1 to Control Lateral Root Formation in Arabidopsis.” <i>International Journal
    of Molecular Sciences</i>. MDPI, 2021. <a href="https://doi.org/10.3390/ijms22083862">https://doi.org/10.3390/ijms22083862</a>.
  ieee: K. Ötvös <i>et al.</i>, “Pickle recruits retinoblastoma related 1 to control
    lateral root formation in arabidopsis,” <i>International Journal of Molecular
    Sciences</i>, vol. 22, no. 8. MDPI, 2021.
  ista: Ötvös K, Miskolczi P, Marhavý P, Cruz-Ramírez A, Benková E, Robert S, Bakó
    L. 2021. Pickle recruits retinoblastoma related 1 to control lateral root formation
    in arabidopsis. International Journal of Molecular Sciences. 22(8), 3862.
  mla: Ötvös, Krisztina, et al. “Pickle Recruits Retinoblastoma Related 1 to Control
    Lateral Root Formation in Arabidopsis.” <i>International Journal of Molecular
    Sciences</i>, vol. 22, no. 8, 3862, MDPI, 2021, doi:<a href="https://doi.org/10.3390/ijms22083862">10.3390/ijms22083862</a>.
  short: K. Ötvös, P. Miskolczi, P. Marhavý, A. Cruz-Ramírez, E. Benková, S. Robert,
    L. Bakó, International Journal of Molecular Sciences 22 (2021).
date_created: 2021-04-18T22:01:41Z
date_published: 2021-04-08T00:00:00Z
date_updated: 2023-08-08T13:09:58Z
day: '08'
ddc:
- '570'
department:
- _id: EvBe
doi: 10.3390/ijms22083862
external_id:
  isi:
  - '000644394800001'
file:
- access_level: open_access
  checksum: 26ada2531ad1f9c01a1664de0431f1fe
  content_type: application/pdf
  creator: dernst
  date_created: 2021-04-19T10:54:55Z
  date_updated: 2021-04-19T10:54:55Z
  file_id: '9342'
  file_name: 2021_JourMolecularScience_Oetvoes.pdf
  file_size: 2769717
  relation: main_file
  success: 1
file_date_updated: 2021-04-19T10:54:55Z
has_accepted_license: '1'
intvolume: '        22'
isi: 1
issue: '8'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: International Journal of Molecular Sciences
publication_identifier:
  eissn:
  - 1422-0067
  issn:
  - 1661-6596
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Pickle recruits retinoblastoma related 1 to control lateral root formation
  in arabidopsis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 22
year: '2021'
...
---
_id: '9986'
abstract:
- lang: eng
  text: Size control is a fundamental question in biology, showing incremental complexity
    in plants, whose cells possess a rigid cell wall. The phytohormone auxin is a
    vital growth regulator with central importance for differential growth control.
    Our results indicate that auxin-reliant growth programs affect the molecular complexity
    of xyloglucans, the major type of cell wall hemicellulose in eudicots. Auxin-dependent
    induction and repression of growth coincide with reduced and enhanced molecular
    complexity of xyloglucans, respectively. In agreement with a proposed function
    in growth control, genetic interference with xyloglucan side decorations distinctly
    modulates auxin-dependent differential growth rates. Our work proposes that auxin-dependent
    growth programs have a spatially defined effect on xyloglucan’s molecular structure,
    which in turn affects cell wall mechanics and specifies differential, gravitropic
    hypocotyl growth.
acknowledgement: "We are grateful to Paul Knox, Markus Pauly, Malcom O’Neill, and
  Ignacio Zarra for providing published material; the BOKU-VIBT Imaging Center for
  access and M. Debreczeny for expertise; J.I. Thaker and Georg Seifert for critical
  reading.\r\n"
article_number: '9222'
article_processing_charge: Yes
article_type: original
author:
- first_name: Silvia Melina
  full_name: Velasquez, Silvia Melina
  last_name: Velasquez
- first_name: Xiaoyuan
  full_name: Guo, Xiaoyuan
  last_name: Guo
- first_name: Marçal
  full_name: Gallemi, Marçal
  id: 460C6802-F248-11E8-B48F-1D18A9856A87
  last_name: Gallemi
  orcid: 0000-0003-4675-6893
- first_name: Bibek
  full_name: Aryal, Bibek
  last_name: Aryal
- first_name: Peter
  full_name: Venhuizen, Peter
  last_name: Venhuizen
- first_name: Elke
  full_name: Barbez, Elke
  last_name: Barbez
- first_name: Kai Alexander
  full_name: Dünser, Kai Alexander
  last_name: Dünser
- first_name: Martin
  full_name: Darino, Martin
  last_name: Darino
- first_name: Aleš
  full_name: Pӗnčík, Aleš
  last_name: Pӗnčík
- first_name: Ondřej
  full_name: Novák, Ondřej
  last_name: Novák
- first_name: Maria
  full_name: Kalyna, Maria
  last_name: Kalyna
- first_name: Gregory
  full_name: Mouille, Gregory
  last_name: Mouille
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Rishikesh P.
  full_name: Bhalerao, Rishikesh P.
  last_name: Bhalerao
- first_name: Jozef
  full_name: Mravec, Jozef
  last_name: Mravec
- first_name: Jürgen
  full_name: Kleine-Vehn, Jürgen
  last_name: Kleine-Vehn
citation:
  ama: Velasquez SM, Guo X, Gallemi M, et al. Xyloglucan remodeling defines auxin-dependent
    differential tissue expansion in plants. <i>International Journal of Molecular
    Sciences</i>. 2021;22(17). doi:<a href="https://doi.org/10.3390/ijms22179222">10.3390/ijms22179222</a>
  apa: Velasquez, S. M., Guo, X., Gallemi, M., Aryal, B., Venhuizen, P., Barbez, E.,
    … Kleine-Vehn, J. (2021). Xyloglucan remodeling defines auxin-dependent differential
    tissue expansion in plants. <i>International Journal of Molecular Sciences</i>.
    MDPI. <a href="https://doi.org/10.3390/ijms22179222">https://doi.org/10.3390/ijms22179222</a>
  chicago: Velasquez, Silvia Melina, Xiaoyuan Guo, Marçal Gallemi, Bibek Aryal, Peter
    Venhuizen, Elke Barbez, Kai Alexander Dünser, et al. “Xyloglucan Remodeling Defines
    Auxin-Dependent Differential Tissue Expansion in Plants.” <i>International Journal
    of Molecular Sciences</i>. MDPI, 2021. <a href="https://doi.org/10.3390/ijms22179222">https://doi.org/10.3390/ijms22179222</a>.
  ieee: S. M. Velasquez <i>et al.</i>, “Xyloglucan remodeling defines auxin-dependent
    differential tissue expansion in plants,” <i>International Journal of Molecular
    Sciences</i>, vol. 22, no. 17. MDPI, 2021.
  ista: Velasquez SM, Guo X, Gallemi M, Aryal B, Venhuizen P, Barbez E, Dünser KA,
    Darino M, Pӗnčík A, Novák O, Kalyna M, Mouille G, Benková E, Bhalerao RP, Mravec
    J, Kleine-Vehn J. 2021. Xyloglucan remodeling defines auxin-dependent differential
    tissue expansion in plants. International Journal of Molecular Sciences. 22(17),
    9222.
  mla: Velasquez, Silvia Melina, et al. “Xyloglucan Remodeling Defines Auxin-Dependent
    Differential Tissue Expansion in Plants.” <i>International Journal of Molecular
    Sciences</i>, vol. 22, no. 17, 9222, MDPI, 2021, doi:<a href="https://doi.org/10.3390/ijms22179222">10.3390/ijms22179222</a>.
  short: S.M. Velasquez, X. Guo, M. Gallemi, B. Aryal, P. Venhuizen, E. Barbez, K.A.
    Dünser, M. Darino, A. Pӗnčík, O. Novák, M. Kalyna, G. Mouille, E. Benková, R.P.
    Bhalerao, J. Mravec, J. Kleine-Vehn, International Journal of Molecular Sciences
    22 (2021).
date_created: 2021-09-05T22:01:24Z
date_published: 2021-08-26T00:00:00Z
date_updated: 2023-10-31T19:29:38Z
day: '26'
ddc:
- '575'
department:
- _id: EvBe
doi: 10.3390/ijms22179222
external_id:
  isi:
  - '000694347100001'
  pmid:
  - '34502129'
file:
- access_level: open_access
  checksum: 6b7055cf89f1b7ed8594c3fdf56f000b
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-09-06T12:50:19Z
  date_updated: 2021-09-07T09:04:53Z
  file_id: '9988'
  file_name: 2021_IntJMolecularSciences_Velasquez.pdf
  file_size: 2162247
  relation: main_file
file_date_updated: 2021-09-07T09:04:53Z
has_accepted_license: '1'
intvolume: '        22'
isi: 1
issue: '17'
keyword:
- auxin
- growth
- cell wall
- xyloglucans
- hypocotyls
- gravitropism
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: International Journal of Molecular Sciences
publication_identifier:
  eissn:
  - 1422-0067
  issn:
  - 1661-6596
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Xyloglucan remodeling defines auxin-dependent differential tissue expansion
  in plants
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 22
year: '2021'
...