---
_id: '9381'
abstract:
- lang: eng
  text: 'A game of rock-paper-scissors is an interesting example of an interaction
    where none of the pure strategies strictly dominates all others, leading to a
    cyclic pattern. In this work, we consider an unstable version of rock-paper-scissors
    dynamics and allow individuals to make behavioural mistakes during the strategy
    execution. We show that such an assumption can break a cyclic relationship leading
    to a stable equilibrium emerging with only one strategy surviving. We consider
    two cases: completely random mistakes when individuals have no bias towards any
    strategy and a general form of mistakes. Then, we determine conditions for a strategy
    to dominate all other strategies. However, given that individuals who adopt a
    dominating strategy are still prone to behavioural mistakes in the observed behaviour,
    we may still observe extinct strategies. That is, behavioural mistakes in strategy
    execution stabilise evolutionary dynamics leading to an evolutionary stable and,
    potentially, mixed co-existence equilibrium.'
acknowledgement: Authors would like to thank Christian Hilbe and Martin Nowak for
  their inspiring and very helpful feedback on the manuscript.
article_number: e1008523
article_processing_charge: No
article_type: original
author:
- first_name: Maria
  full_name: Kleshnina, Maria
  id: 4E21749C-F248-11E8-B48F-1D18A9856A87
  last_name: Kleshnina
- first_name: Sabrina S.
  full_name: Streipert, Sabrina S.
  last_name: Streipert
- first_name: Jerzy A.
  full_name: Filar, Jerzy A.
  last_name: Filar
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
citation:
  ama: Kleshnina M, Streipert SS, Filar JA, Chatterjee K. Mistakes can stabilise the
    dynamics of rock-paper-scissors games. <i>PLoS Computational Biology</i>. 2021;17(4).
    doi:<a href="https://doi.org/10.1371/journal.pcbi.1008523">10.1371/journal.pcbi.1008523</a>
  apa: Kleshnina, M., Streipert, S. S., Filar, J. A., &#38; Chatterjee, K. (2021).
    Mistakes can stabilise the dynamics of rock-paper-scissors games. <i>PLoS Computational
    Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1008523">https://doi.org/10.1371/journal.pcbi.1008523</a>
  chicago: Kleshnina, Maria, Sabrina S. Streipert, Jerzy A. Filar, and Krishnendu
    Chatterjee. “Mistakes Can Stabilise the Dynamics of Rock-Paper-Scissors Games.”
    <i>PLoS Computational Biology</i>. Public Library of Science, 2021. <a href="https://doi.org/10.1371/journal.pcbi.1008523">https://doi.org/10.1371/journal.pcbi.1008523</a>.
  ieee: M. Kleshnina, S. S. Streipert, J. A. Filar, and K. Chatterjee, “Mistakes can
    stabilise the dynamics of rock-paper-scissors games,” <i>PLoS Computational Biology</i>,
    vol. 17, no. 4. Public Library of Science, 2021.
  ista: Kleshnina M, Streipert SS, Filar JA, Chatterjee K. 2021. Mistakes can stabilise
    the dynamics of rock-paper-scissors games. PLoS Computational Biology. 17(4),
    e1008523.
  mla: Kleshnina, Maria, et al. “Mistakes Can Stabilise the Dynamics of Rock-Paper-Scissors
    Games.” <i>PLoS Computational Biology</i>, vol. 17, no. 4, e1008523, Public Library
    of Science, 2021, doi:<a href="https://doi.org/10.1371/journal.pcbi.1008523">10.1371/journal.pcbi.1008523</a>.
  short: M. Kleshnina, S.S. Streipert, J.A. Filar, K. Chatterjee, PLoS Computational
    Biology 17 (2021).
date_created: 2021-05-09T22:01:38Z
date_published: 2021-04-01T00:00:00Z
date_updated: 2025-07-14T09:10:04Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1371/journal.pcbi.1008523
ec_funded: 1
external_id:
  isi:
  - '000639711200001'
file:
- access_level: open_access
  checksum: a94ebe0c4116f5047eaa6029e54d2dac
  content_type: application/pdf
  creator: kschuh
  date_created: 2021-05-11T13:50:06Z
  date_updated: 2021-05-11T13:50:06Z
  file_id: '9385'
  file_name: 2021_pcbi_Kleshnina.pdf
  file_size: 1323820
  relation: main_file
  success: 1
file_date_updated: 2021-05-11T13:50:06Z
has_accepted_license: '1'
intvolume: '        17'
isi: 1
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: PLoS Computational Biology
publication_identifier:
  eissn:
  - '15537358'
  issn:
  - 1553734X
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mistakes can stabilise the dynamics of rock-paper-scissors games
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 17
year: '2021'
...
---
_id: '9759'
acknowledgement: The authors thank Inez Lam of Johns Hopkins University for valuable
  comments on an earlier version of the manuscript. We also thank the facilitators
  of the 2019–2020 eLife Community Ambassador program.
article_number: e1009124
article_processing_charge: Yes
article_type: letter_note
author:
- first_name: Michael John
  full_name: Bartlett, Michael John
  last_name: Bartlett
- first_name: Feyza N
  full_name: Arslan, Feyza N
  id: 49DA7910-F248-11E8-B48F-1D18A9856A87
  last_name: Arslan
  orcid: 0000-0001-5809-9566
- first_name: Adriana
  full_name: Bankston, Adriana
  last_name: Bankston
- first_name: Sarvenaz
  full_name: Sarabipour, Sarvenaz
  last_name: Sarabipour
citation:
  ama: Bartlett MJ, Arslan FN, Bankston A, Sarabipour S. Ten simple rules to improve
    academic work- life balance. <i>PLoS Computational Biology</i>. 2021;17(7). doi:<a
    href="https://doi.org/10.1371/journal.pcbi.1009124">10.1371/journal.pcbi.1009124</a>
  apa: Bartlett, M. J., Arslan, F. N., Bankston, A., &#38; Sarabipour, S. (2021).
    Ten simple rules to improve academic work- life balance. <i>PLoS Computational
    Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1009124">https://doi.org/10.1371/journal.pcbi.1009124</a>
  chicago: Bartlett, Michael John, Feyza N Arslan, Adriana Bankston, and Sarvenaz
    Sarabipour. “Ten Simple Rules to Improve Academic Work- Life Balance.” <i>PLoS
    Computational Biology</i>. Public Library of Science, 2021. <a href="https://doi.org/10.1371/journal.pcbi.1009124">https://doi.org/10.1371/journal.pcbi.1009124</a>.
  ieee: M. J. Bartlett, F. N. Arslan, A. Bankston, and S. Sarabipour, “Ten simple
    rules to improve academic work- life balance,” <i>PLoS Computational Biology</i>,
    vol. 17, no. 7. Public Library of Science, 2021.
  ista: Bartlett MJ, Arslan FN, Bankston A, Sarabipour S. 2021. Ten simple rules to
    improve academic work- life balance. PLoS Computational Biology. 17(7), e1009124.
  mla: Bartlett, Michael John, et al. “Ten Simple Rules to Improve Academic Work-
    Life Balance.” <i>PLoS Computational Biology</i>, vol. 17, no. 7, e1009124, Public
    Library of Science, 2021, doi:<a href="https://doi.org/10.1371/journal.pcbi.1009124">10.1371/journal.pcbi.1009124</a>.
  short: M.J. Bartlett, F.N. Arslan, A. Bankston, S. Sarabipour, PLoS Computational
    Biology 17 (2021).
date_created: 2021-08-01T22:01:21Z
date_published: 2021-07-15T00:00:00Z
date_updated: 2023-08-10T14:16:46Z
day: '15'
ddc:
- '613'
department:
- _id: CaHe
doi: 10.1371/journal.pcbi.1009124
external_id:
  isi:
  - '000677713500008'
  pmid:
  - '34264932'
file:
- access_level: open_access
  checksum: e56d91f0eeadb36f143a90e2c1b3ab63
  content_type: application/pdf
  creator: cchlebak
  date_created: 2021-08-05T12:06:49Z
  date_updated: 2021-08-05T12:06:49Z
  file_id: '9771'
  file_name: 2021_PlosCompBio_Bartlett.pdf
  file_size: 693633
  relation: main_file
file_date_updated: 2021-08-05T12:06:49Z
has_accepted_license: '1'
intvolume: '        17'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Computational Biology
publication_identifier:
  eissn:
  - '15537358'
  issn:
  - 1553734X
publication_status: published
publisher: Public Library of Science
scopus_import: '1'
status: public
title: Ten simple rules to improve academic work- life balance
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 17
year: '2021'
...
---
_id: '680'
abstract:
- lang: eng
  text: In order to respond reliably to specific features of their environment, sensory
    neurons need to integrate multiple incoming noisy signals. Crucially, they also
    need to compete for the interpretation of those signals with other neurons representing
    similar features. The form that this competition should take depends critically
    on the noise corrupting these signals. In this study we show that for the type
    of noise commonly observed in sensory systems, whose variance scales with the
    mean signal, sensory neurons should selectively divide their input signals by
    their predictions, suppressing ambiguous cues while amplifying others. Any change
    in the stimulus context alters which inputs are suppressed, leading to a deep
    dynamic reshaping of neural receptive fields going far beyond simple surround
    suppression. Paradoxically, these highly variable receptive fields go alongside
    and are in fact required for an invariant representation of external sensory features.
    In addition to offering a normative account of context-dependent changes in sensory
    responses, perceptual inference in the presence of signal-dependent noise accounts
    for ubiquitous features of sensory neurons such as divisive normalization, gain
    control and contrast dependent temporal dynamics.
article_number: e1005582
author:
- first_name: Matthew J
  full_name: Chalk, Matthew J
  id: 2BAAC544-F248-11E8-B48F-1D18A9856A87
  last_name: Chalk
  orcid: 0000-0001-7782-4436
- first_name: Paul
  full_name: Masset, Paul
  last_name: Masset
- first_name: Boris
  full_name: Gutkin, Boris
  last_name: Gutkin
- first_name: Sophie
  full_name: Denève, Sophie
  last_name: Denève
citation:
  ama: Chalk MJ, Masset P, Gutkin B, Denève S. Sensory noise predicts divisive reshaping
    of receptive fields. <i>PLoS Computational Biology</i>. 2017;13(6). doi:<a href="https://doi.org/10.1371/journal.pcbi.1005582">10.1371/journal.pcbi.1005582</a>
  apa: Chalk, M. J., Masset, P., Gutkin, B., &#38; Denève, S. (2017). Sensory noise
    predicts divisive reshaping of receptive fields. <i>PLoS Computational Biology</i>.
    Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1005582">https://doi.org/10.1371/journal.pcbi.1005582</a>
  chicago: Chalk, Matthew J, Paul Masset, Boris Gutkin, and Sophie Denève. “Sensory
    Noise Predicts Divisive Reshaping of Receptive Fields.” <i>PLoS Computational
    Biology</i>. Public Library of Science, 2017. <a href="https://doi.org/10.1371/journal.pcbi.1005582">https://doi.org/10.1371/journal.pcbi.1005582</a>.
  ieee: M. J. Chalk, P. Masset, B. Gutkin, and S. Denève, “Sensory noise predicts
    divisive reshaping of receptive fields,” <i>PLoS Computational Biology</i>, vol.
    13, no. 6. Public Library of Science, 2017.
  ista: Chalk MJ, Masset P, Gutkin B, Denève S. 2017. Sensory noise predicts divisive
    reshaping of receptive fields. PLoS Computational Biology. 13(6), e1005582.
  mla: Chalk, Matthew J., et al. “Sensory Noise Predicts Divisive Reshaping of Receptive
    Fields.” <i>PLoS Computational Biology</i>, vol. 13, no. 6, e1005582, Public Library
    of Science, 2017, doi:<a href="https://doi.org/10.1371/journal.pcbi.1005582">10.1371/journal.pcbi.1005582</a>.
  short: M.J. Chalk, P. Masset, B. Gutkin, S. Denève, PLoS Computational Biology 13
    (2017).
date_created: 2018-12-11T11:47:53Z
date_published: 2017-06-01T00:00:00Z
date_updated: 2023-02-23T14:10:54Z
day: '01'
ddc:
- '571'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1005582
file:
- access_level: open_access
  checksum: 796a1026076af6f4405a47d985bc7b68
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:07:47Z
  date_updated: 2020-07-14T12:47:40Z
  file_id: '4645'
  file_name: IST-2017-898-v1+1_journal.pcbi.1005582.pdf
  file_size: 14555676
  relation: main_file
file_date_updated: 2020-07-14T12:47:40Z
has_accepted_license: '1'
intvolume: '        13'
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: PLoS Computational Biology
publication_identifier:
  issn:
  - 1553734X
publication_status: published
publisher: Public Library of Science
publist_id: '7035'
pubrep_id: '898'
quality_controlled: '1'
related_material:
  record:
  - id: '9855'
    relation: research_data
    status: public
scopus_import: 1
status: public
title: Sensory noise predicts divisive reshaping of receptive fields
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2017'
...
---
_id: '696'
abstract:
- lang: eng
  text: Mutator strains are expected to evolve when the availability and effect of
    beneficial mutations are high enough to counteract the disadvantage from deleterious
    mutations that will inevitably accumulate. As the population becomes more adapted
    to its environment, both availability and effect of beneficial mutations necessarily
    decrease and mutation rates are predicted to decrease. It has been shown that
    certain molecular mechanisms can lead to increased mutation rates when the organism
    finds itself in a stressful environment. While this may be a correlated response
    to other functions, it could also be an adaptive mechanism, raising mutation rates
    only when it is most advantageous. Here, we use a mathematical model to investigate
    the plausibility of the adaptive hypothesis. We show that such a mechanism can
    be mantained if the population is subjected to diverse stresses. By simulating
    various antibiotic treatment schemes, we find that combination treatments can
    reduce the effectiveness of second-order selection on stress-induced mutagenesis.
    We discuss the implications of our results to strategies of antibiotic therapy.
article_number: e1005609
article_type: original
author:
- first_name: Marta
  full_name: Lukacisinova, Marta
  id: 4342E402-F248-11E8-B48F-1D18A9856A87
  last_name: Lukacisinova
  orcid: 0000-0002-2519-8004
- first_name: Sebastian
  full_name: Novak, Sebastian
  id: 461468AE-F248-11E8-B48F-1D18A9856A87
  last_name: Novak
  orcid: 0000-0002-2519-824X
- first_name: Tiago
  full_name: Paixao, Tiago
  id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
  last_name: Paixao
  orcid: 0000-0003-2361-3953
citation:
  ama: 'Lukacisinova M, Novak S, Paixao T. Stress induced mutagenesis: Stress diversity
    facilitates the persistence of mutator genes. <i>PLoS Computational Biology</i>.
    2017;13(7). doi:<a href="https://doi.org/10.1371/journal.pcbi.1005609">10.1371/journal.pcbi.1005609</a>'
  apa: 'Lukacisinova, M., Novak, S., &#38; Paixao, T. (2017). Stress induced mutagenesis:
    Stress diversity facilitates the persistence of mutator genes. <i>PLoS Computational
    Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1005609">https://doi.org/10.1371/journal.pcbi.1005609</a>'
  chicago: 'Lukacisinova, Marta, Sebastian Novak, and Tiago Paixao. “Stress Induced
    Mutagenesis: Stress Diversity Facilitates the Persistence of Mutator Genes.” <i>PLoS
    Computational Biology</i>. Public Library of Science, 2017. <a href="https://doi.org/10.1371/journal.pcbi.1005609">https://doi.org/10.1371/journal.pcbi.1005609</a>.'
  ieee: 'M. Lukacisinova, S. Novak, and T. Paixao, “Stress induced mutagenesis: Stress
    diversity facilitates the persistence of mutator genes,” <i>PLoS Computational
    Biology</i>, vol. 13, no. 7. Public Library of Science, 2017.'
  ista: 'Lukacisinova M, Novak S, Paixao T. 2017. Stress induced mutagenesis: Stress
    diversity facilitates the persistence of mutator genes. PLoS Computational Biology.
    13(7), e1005609.'
  mla: 'Lukacisinova, Marta, et al. “Stress Induced Mutagenesis: Stress Diversity
    Facilitates the Persistence of Mutator Genes.” <i>PLoS Computational Biology</i>,
    vol. 13, no. 7, e1005609, Public Library of Science, 2017, doi:<a href="https://doi.org/10.1371/journal.pcbi.1005609">10.1371/journal.pcbi.1005609</a>.'
  short: M. Lukacisinova, S. Novak, T. Paixao, PLoS Computational Biology 13 (2017).
date_created: 2018-12-11T11:47:58Z
date_published: 2017-07-18T00:00:00Z
date_updated: 2024-03-25T23:30:14Z
day: '18'
ddc:
- '576'
department:
- _id: ToBo
- _id: NiBa
- _id: CaGu
doi: 10.1371/journal.pcbi.1005609
ec_funded: 1
file:
- access_level: open_access
  checksum: 9143c290fa6458ed2563bff4b295554a
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:15:01Z
  date_updated: 2020-07-14T12:47:46Z
  file_id: '5117'
  file_name: IST-2017-894-v1+1_journal.pcbi.1005609.pdf
  file_size: 3775716
  relation: main_file
file_date_updated: 2020-07-14T12:47:46Z
has_accepted_license: '1'
intvolume: '        13'
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 25B1EC9E-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '618091'
  name: Speed of Adaptation in Population Genetics and Evolutionary Computation
publication: PLoS Computational Biology
publication_identifier:
  issn:
  - 1553734X
publication_status: published
publisher: Public Library of Science
publist_id: '7004'
pubrep_id: '894'
quality_controlled: '1'
related_material:
  record:
  - id: '9849'
    relation: research_data
    status: public
  - id: '9850'
    relation: research_data
    status: public
  - id: '9851'
    relation: research_data
    status: public
  - id: '9852'
    relation: research_data
    status: public
  - id: '6263'
    relation: dissertation_contains
    status: public
scopus_import: 1
status: public
title: 'Stress induced mutagenesis: Stress diversity facilitates the persistence of
  mutator genes'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2017'
...
---
_id: '720'
abstract:
- lang: eng
  text: 'Advances in multi-unit recordings pave the way for statistical modeling of
    activity patterns in large neural populations. Recent studies have shown that
    the summed activity of all neurons strongly shapes the population response. A
    separate recent finding has been that neural populations also exhibit criticality,
    an anomalously large dynamic range for the probabilities of different population
    activity patterns. Motivated by these two observations, we introduce a class of
    probabilistic models which takes into account the prior knowledge that the neural
    population could be globally coupled and close to critical. These models consist
    of an energy function which parametrizes interactions between small groups of
    neurons, and an arbitrary positive, strictly increasing, and twice differentiable
    function which maps the energy of a population pattern to its probability. We
    show that: 1) augmenting a pairwise Ising model with a nonlinearity yields an
    accurate description of the activity of retinal ganglion cells which outperforms
    previous models based on the summed activity of neurons; 2) prior knowledge that
    the population is critical translates to prior expectations about the shape of
    the nonlinearity; 3) the nonlinearity admits an interpretation in terms of a continuous
    latent variable globally coupling the system whose distribution we can infer from
    data. Our method is independent of the underlying system’s state space; hence,
    it can be applied to other systems such as natural scenes or amino acid sequences
    of proteins which are also known to exhibit criticality.'
article_number: e1005763
article_processing_charge: Yes
author:
- first_name: Jan
  full_name: Humplik, Jan
  id: 2E9627A8-F248-11E8-B48F-1D18A9856A87
  last_name: Humplik
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
citation:
  ama: Humplik J, Tkačik G. Probabilistic models for neural populations that naturally
    capture global coupling and criticality. <i>PLoS Computational Biology</i>. 2017;13(9).
    doi:<a href="https://doi.org/10.1371/journal.pcbi.1005763">10.1371/journal.pcbi.1005763</a>
  apa: Humplik, J., &#38; Tkačik, G. (2017). Probabilistic models for neural populations
    that naturally capture global coupling and criticality. <i>PLoS Computational
    Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1005763">https://doi.org/10.1371/journal.pcbi.1005763</a>
  chicago: Humplik, Jan, and Gašper Tkačik. “Probabilistic Models for Neural Populations
    That Naturally Capture Global Coupling and Criticality.” <i>PLoS Computational
    Biology</i>. Public Library of Science, 2017. <a href="https://doi.org/10.1371/journal.pcbi.1005763">https://doi.org/10.1371/journal.pcbi.1005763</a>.
  ieee: J. Humplik and G. Tkačik, “Probabilistic models for neural populations that
    naturally capture global coupling and criticality,” <i>PLoS Computational Biology</i>,
    vol. 13, no. 9. Public Library of Science, 2017.
  ista: Humplik J, Tkačik G. 2017. Probabilistic models for neural populations that
    naturally capture global coupling and criticality. PLoS Computational Biology.
    13(9), e1005763.
  mla: Humplik, Jan, and Gašper Tkačik. “Probabilistic Models for Neural Populations
    That Naturally Capture Global Coupling and Criticality.” <i>PLoS Computational
    Biology</i>, vol. 13, no. 9, e1005763, Public Library of Science, 2017, doi:<a
    href="https://doi.org/10.1371/journal.pcbi.1005763">10.1371/journal.pcbi.1005763</a>.
  short: J. Humplik, G. Tkačik, PLoS Computational Biology 13 (2017).
date_created: 2018-12-11T11:48:08Z
date_published: 2017-09-19T00:00:00Z
date_updated: 2021-01-12T08:12:21Z
day: '19'
ddc:
- '530'
- '571'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1005763
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intvolume: '        13'
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 255008E4-B435-11E9-9278-68D0E5697425
  grant_number: RGP0065/2012
  name: Information processing and computation in fish groups
- _id: 254D1A94-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 25651-N26
  name: Sensitivity to higher-order statistics in natural scenes
publication: PLoS Computational Biology
publication_identifier:
  issn:
  - 1553734X
publication_status: published
publisher: Public Library of Science
publist_id: '6960'
pubrep_id: '884'
quality_controlled: '1'
scopus_import: 1
status: public
title: Probabilistic models for neural populations that naturally capture global coupling
  and criticality
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2017'
...
---
_id: '2257'
abstract:
- lang: eng
  text: 'Maximum entropy models are the least structured probability distributions
    that exactly reproduce a chosen set of statistics measured in an interacting network.
    Here we use this principle to construct probabilistic models which describe the
    correlated spiking activity of populations of up to 120 neurons in the salamander
    retina as it responds to natural movies. Already in groups as small as 10 neurons,
    interactions between spikes can no longer be regarded as small perturbations in
    an otherwise independent system; for 40 or more neurons pairwise interactions
    need to be supplemented by a global interaction that controls the distribution
    of synchrony in the population. Here we show that such “K-pairwise” models—being
    systematic extensions of the previously used pairwise Ising models—provide an
    excellent account of the data. We explore the properties of the neural vocabulary
    by: 1) estimating its entropy, which constrains the population''s capacity to
    represent visual information; 2) classifying activity patterns into a small set
    of metastable collective modes; 3) showing that the neural codeword ensembles
    are extremely inhomogenous; 4) demonstrating that the state of individual neurons
    is highly predictable from the rest of the population, allowing the capacity for
    error correction.'
acknowledgement: "\r\n\r\n\r\n\r\nThis work was funded by NSF grant IIS-0613435, NSF
  grant PHY-0957573, NSF grant CCF-0939370, NIH grant R01 EY14196, NIH grant P50 GM071508,
  the Fannie and John Hertz Foundation, the Swartz Foundation, the WM Keck Foundation,
  ANR Optima and the French State program “Investissements d'Avenir” [LIFESENSES:
  ANR-10-LABX-65], and the Austrian Research Foundation FWF P25651."
article_number: e1003408
author:
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
- first_name: Olivier
  full_name: Marre, Olivier
  last_name: Marre
- first_name: Dario
  full_name: Amodei, Dario
  last_name: Amodei
- first_name: Elad
  full_name: Schneidman, Elad
  last_name: Schneidman
- first_name: William
  full_name: Bialek, William
  last_name: Bialek
- first_name: Michael
  full_name: Berry, Michael
  last_name: Berry
citation:
  ama: Tkačik G, Marre O, Amodei D, Schneidman E, Bialek W, Berry M. Searching for
    collective behavior in a large network of sensory neurons. <i>PLoS Computational
    Biology</i>. 2014;10(1). doi:<a href="https://doi.org/10.1371/journal.pcbi.1003408">10.1371/journal.pcbi.1003408</a>
  apa: Tkačik, G., Marre, O., Amodei, D., Schneidman, E., Bialek, W., &#38; Berry,
    M. (2014). Searching for collective behavior in a large network of sensory neurons.
    <i>PLoS Computational Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1003408">https://doi.org/10.1371/journal.pcbi.1003408</a>
  chicago: Tkačik, Gašper, Olivier Marre, Dario Amodei, Elad Schneidman, William Bialek,
    and Michael Berry. “Searching for Collective Behavior in a Large Network of Sensory
    Neurons.” <i>PLoS Computational Biology</i>. Public Library of Science, 2014.
    <a href="https://doi.org/10.1371/journal.pcbi.1003408">https://doi.org/10.1371/journal.pcbi.1003408</a>.
  ieee: G. Tkačik, O. Marre, D. Amodei, E. Schneidman, W. Bialek, and M. Berry, “Searching
    for collective behavior in a large network of sensory neurons,” <i>PLoS Computational
    Biology</i>, vol. 10, no. 1. Public Library of Science, 2014.
  ista: Tkačik G, Marre O, Amodei D, Schneidman E, Bialek W, Berry M. 2014. Searching
    for collective behavior in a large network of sensory neurons. PLoS Computational
    Biology. 10(1), e1003408.
  mla: Tkačik, Gašper, et al. “Searching for Collective Behavior in a Large Network
    of Sensory Neurons.” <i>PLoS Computational Biology</i>, vol. 10, no. 1, e1003408,
    Public Library of Science, 2014, doi:<a href="https://doi.org/10.1371/journal.pcbi.1003408">10.1371/journal.pcbi.1003408</a>.
  short: G. Tkačik, O. Marre, D. Amodei, E. Schneidman, W. Bialek, M. Berry, PLoS
    Computational Biology 10 (2014).
date_created: 2018-12-11T11:56:36Z
date_published: 2014-01-02T00:00:00Z
date_updated: 2024-02-21T13:46:14Z
day: '02'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1003408
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  date_created: 2018-12-12T10:12:46Z
  date_updated: 2020-07-14T12:45:35Z
  file_id: '4965'
  file_name: IST-2016-436-v1+1_journal.pcbi.1003408.pdf
  file_size: 2194790
  relation: main_file
file_date_updated: 2020-07-14T12:45:35Z
has_accepted_license: '1'
intvolume: '        10'
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  url: http://repository.ist.ac.at/id/eprint/436
month: '01'
oa: 1
oa_version: Published Version
publication: PLoS Computational Biology
publication_identifier:
  issn:
  - 1553734X
publication_status: published
publisher: Public Library of Science
publist_id: '4689'
pubrep_id: '436'
quality_controlled: '1'
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scopus_import: 1
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title: Searching for collective behavior in a large network of sensory neurons
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2014'
...
