---
_id: '12668'
abstract:
- lang: eng
text: "Background: Plant and animal embryogenesis have conserved and distinct features.
Cell fate transitions occur during embryogenesis in both plants and animals. The
epigenomic processes regulating plant embryogenesis remain largely elusive.\r\n\r\nResults:
Here, we elucidate chromatin and transcriptomic dynamics during embryogenesis
of the most cultivated crop, hexaploid wheat. Time-series analysis reveals stage-specific
and proximal–distal distinct chromatin accessibility and dynamics concordant with
transcriptome changes. Following fertilization, the remodeling kinetics of H3K4me3,
H3K27ac, and H3K27me3 differ from that in mammals, highlighting considerable species-specific
epigenomic dynamics during zygotic genome activation. Polycomb repressive complex
2 (PRC2)-mediated H3K27me3 deposition is important for embryo establishment. Later
H3K27ac, H3K27me3, and chromatin accessibility undergo dramatic remodeling to
establish a permissive chromatin environment facilitating the access of transcription
factors to cis-elements for fate patterning. Embryonic maturation is characterized
by increasing H3K27me3 and decreasing chromatin accessibility, which likely participates
in restricting totipotency while preventing extensive organogenesis. Finally,
epigenomic signatures are correlated with biased expression among homeolog triads
and divergent expression after polyploidization, revealing an epigenomic contributor
to subgenome diversification in an allohexaploid genome.\r\n\r\nConclusions: Collectively,
we present an invaluable resource for comparative and mechanistic analysis of
the epigenomic regulation of crop embryogenesis."
article_number: '7'
article_processing_charge: No
article_type: original
author:
- first_name: Long
full_name: Zhao, Long
last_name: Zhao
- first_name: Yiman
full_name: Yang, Yiman
last_name: Yang
- first_name: Jinchao
full_name: Chen, Jinchao
last_name: Chen
- first_name: Xuelei
full_name: Lin, Xuelei
last_name: Lin
- first_name: Hao
full_name: Zhang, Hao
last_name: Zhang
- first_name: Hao
full_name: Wang, Hao
last_name: Wang
- first_name: Hongzhe
full_name: Wang, Hongzhe
last_name: Wang
- first_name: Xiaomin
full_name: Bie, Xiaomin
last_name: Bie
- first_name: Jiafu
full_name: Jiang, Jiafu
last_name: Jiang
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
- first_name: Xiangdong
full_name: Fu, Xiangdong
last_name: Fu
- first_name: Xiansheng
full_name: Zhang, Xiansheng
last_name: Zhang
- first_name: Zhuo
full_name: Du, Zhuo
last_name: Du
- first_name: Jun
full_name: Xiao, Jun
last_name: Xiao
citation:
ama: Zhao L, Yang Y, Chen J, et al. Dynamic chromatin regulatory programs during
embryogenesis of hexaploid wheat. Genome Biology. 2023;24. doi:10.1186/s13059-022-02844-2
apa: Zhao, L., Yang, Y., Chen, J., Lin, X., Zhang, H., Wang, H., … Xiao, J. (2023).
Dynamic chromatin regulatory programs during embryogenesis of hexaploid wheat.
Genome Biology. Springer Nature. https://doi.org/10.1186/s13059-022-02844-2
chicago: Zhao, Long, Yiman Yang, Jinchao Chen, Xuelei Lin, Hao Zhang, Hao Wang,
Hongzhe Wang, et al. “Dynamic Chromatin Regulatory Programs during Embryogenesis
of Hexaploid Wheat.” Genome Biology. Springer Nature, 2023. https://doi.org/10.1186/s13059-022-02844-2.
ieee: L. Zhao et al., “Dynamic chromatin regulatory programs during embryogenesis
of hexaploid wheat,” Genome Biology, vol. 24. Springer Nature, 2023.
ista: Zhao L, Yang Y, Chen J, Lin X, Zhang H, Wang H, Wang H, Bie X, Jiang J, Feng
X, Fu X, Zhang X, Du Z, Xiao J. 2023. Dynamic chromatin regulatory programs during
embryogenesis of hexaploid wheat. Genome Biology. 24, 7.
mla: Zhao, Long, et al. “Dynamic Chromatin Regulatory Programs during Embryogenesis
of Hexaploid Wheat.” Genome Biology, vol. 24, 7, Springer Nature, 2023,
doi:10.1186/s13059-022-02844-2.
short: L. Zhao, Y. Yang, J. Chen, X. Lin, H. Zhang, H. Wang, H. Wang, X. Bie, J.
Jiang, X. Feng, X. Fu, X. Zhang, Z. Du, J. Xiao, Genome Biology 24 (2023).
date_created: 2023-02-23T09:13:49Z
date_published: 2023-01-13T00:00:00Z
date_updated: 2023-05-08T10:52:49Z
day: '13'
department:
- _id: XiFe
doi: 10.1186/s13059-022-02844-2
extern: '1'
external_id:
pmid:
- '36639687'
intvolume: ' 24'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1186/s13059-022-02844-2
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology
publication_identifier:
issn:
- 1474-760X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamic chromatin regulatory programs during embryogenesis of hexaploid wheat
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2023'
...
---
_id: '12226'
abstract:
- lang: eng
text: "Background: Biases of DNA repair can shape the nucleotide landscape of genomes
at evolutionary timescales. The molecular mechanisms of those biases are still
poorly understood because it is difficult to isolate the contributions of DNA
repair from those of DNA damage.\r\n\r\nResults: Here, we develop a genome-wide
assay whereby the same DNA lesion is repaired in different genomic contexts. We
insert thousands of barcoded transposons carrying a reporter of DNA mismatch repair
in the genome of mouse embryonic stem cells. Upon inducing a double-strand break
between tandem repeats, a mismatch is generated if the break is repaired through
single-strand annealing. The resolution of the mismatch showed a 60–80% bias in
favor of the strand with the longest 3′ flap. The location of the lesion in the
genome and the type of mismatch had little influence on the bias. Instead, we
observe a complete reversal of the bias when the longest 3′ flap is moved to the
opposite strand by changing the position of the double-strand break in the reporter.\r\n\r\nConclusions:
These results suggest that the processing of the double-strand break has a major
influence on the repair of mismatches during single-strand annealing."
acknowledgement: We acknowledge the financial support of the Natural Sciences and
Engineering Research Council of Canada (NSERC RGPIN-2020-06377), the Spanish Ministry
of Economy, Industry and Competitiveness (“Centro de Excelencia Severo Ochoa 2013-2017”,
Plan Estatal PGC2018-099807-B-I00), of the CERCA Programme/Generalitat de Catalunya,
and of the European Research Council (Synergy Grant 609989). VOP was supported by
the European Union’s Horizon 2020 research and innovation program under the Marie
Skłodowska-Curie programme (665385). We also acknowledge the support of the Spanish
Ministry of Economy and Competitiveness (MEIC) to the EMBL partnership.
article_number: '93'
article_processing_charge: No
article_type: original
author:
- first_name: Victoria
full_name: Pokusaeva, Victoria
id: 3184041C-F248-11E8-B48F-1D18A9856A87
last_name: Pokusaeva
orcid: 0000-0001-7660-444X
- first_name: Aránzazu Rosado
full_name: Diez, Aránzazu Rosado
last_name: Diez
- first_name: Lorena
full_name: Espinar, Lorena
last_name: Espinar
- first_name: Albert Torelló
full_name: Pérez, Albert Torelló
last_name: Pérez
- first_name: Guillaume J.
full_name: Filion, Guillaume J.
last_name: Filion
citation:
ama: Pokusaeva V, Diez AR, Espinar L, Pérez AT, Filion GJ. Strand asymmetry influences
mismatch resolution during single-strand annealing. Genome Biology. 2022;23.
doi:10.1186/s13059-022-02665-3
apa: Pokusaeva, V., Diez, A. R., Espinar, L., Pérez, A. T., & Filion, G. J.
(2022). Strand asymmetry influences mismatch resolution during single-strand annealing.
Genome Biology. Springer Nature. https://doi.org/10.1186/s13059-022-02665-3
chicago: Pokusaeva, Victoria, Aránzazu Rosado Diez, Lorena Espinar, Albert Torelló
Pérez, and Guillaume J. Filion. “Strand Asymmetry Influences Mismatch Resolution
during Single-Strand Annealing.” Genome Biology. Springer Nature, 2022.
https://doi.org/10.1186/s13059-022-02665-3.
ieee: V. Pokusaeva, A. R. Diez, L. Espinar, A. T. Pérez, and G. J. Filion, “Strand
asymmetry influences mismatch resolution during single-strand annealing,” Genome
Biology, vol. 23. Springer Nature, 2022.
ista: Pokusaeva V, Diez AR, Espinar L, Pérez AT, Filion GJ. 2022. Strand asymmetry
influences mismatch resolution during single-strand annealing. Genome Biology.
23, 93.
mla: Pokusaeva, Victoria, et al. “Strand Asymmetry Influences Mismatch Resolution
during Single-Strand Annealing.” Genome Biology, vol. 23, 93, Springer
Nature, 2022, doi:10.1186/s13059-022-02665-3.
short: V. Pokusaeva, A.R. Diez, L. Espinar, A.T. Pérez, G.J. Filion, Genome Biology
23 (2022).
date_created: 2023-01-16T09:48:44Z
date_published: 2022-04-12T00:00:00Z
date_updated: 2023-08-04T09:27:00Z
day: '12'
ddc:
- '570'
department:
- _id: MaJö
doi: 10.1186/s13059-022-02665-3
ec_funded: 1
external_id:
isi:
- '000781953800001'
pmid:
- '35414014'
file:
- access_level: open_access
checksum: 17bb091fec04d82ba20a3458c4cfd2bd
content_type: application/pdf
creator: dernst
date_created: 2023-01-27T09:01:40Z
date_updated: 2023-01-27T09:01:40Z
file_id: '12419'
file_name: 2022_GenomeBiology_Pokusaeva.pdf
file_size: 4939342
relation: main_file
success: 1
file_date_updated: 2023-01-27T09:01:40Z
has_accepted_license: '1'
intvolume: ' 23'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: Genome Biology
publication_identifier:
issn:
- 1474-760X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: software
url: 'https://github.com/cellcomplexitylab/strand_asymmetry '
- relation: software
url: https://hub.docker.com/r/gui11aume/strand_asymmetry
scopus_import: '1'
status: public
title: Strand asymmetry influences mismatch resolution during single-strand annealing
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 23
year: '2022'
...
---
_id: '11064'
abstract:
- lang: eng
text: Biomarkers of aging can be used to assess the health of individuals and to
study aging and age-related diseases. We generate a large dataset of genome-wide
RNA-seq profiles of human dermal fibroblasts from 133 people aged 1 to 94 years
old to test whether signatures of aging are encoded within the transcriptome.
We develop an ensemble machine learning method that predicts age to a median error
of 4 years, outperforming previous methods used to predict age. The ensemble was
further validated by testing it on ten progeria patients, and our method is the
only one that predicts accelerated aging in these patients.
article_number: '221'
article_processing_charge: No
article_type: original
author:
- first_name: Jason G.
full_name: Fleischer, Jason G.
last_name: Fleischer
- first_name: Roberta
full_name: Schulte, Roberta
last_name: Schulte
- first_name: Hsiao H.
full_name: Tsai, Hsiao H.
last_name: Tsai
- first_name: Swati
full_name: Tyagi, Swati
last_name: Tyagi
- first_name: Arkaitz
full_name: Ibarra, Arkaitz
last_name: Ibarra
- first_name: Maxim N.
full_name: Shokhirev, Maxim N.
last_name: Shokhirev
- first_name: Ling
full_name: Huang, Ling
last_name: Huang
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
- first_name: Saket
full_name: Navlakha, Saket
last_name: Navlakha
citation:
ama: Fleischer JG, Schulte R, Tsai HH, et al. Predicting age from the transcriptome
of human dermal fibroblasts. Genome Biology. 2018;19. doi:10.1186/s13059-018-1599-6
apa: Fleischer, J. G., Schulte, R., Tsai, H. H., Tyagi, S., Ibarra, A., Shokhirev,
M. N., … Navlakha, S. (2018). Predicting age from the transcriptome of human dermal
fibroblasts. Genome Biology. BioMed Central. https://doi.org/10.1186/s13059-018-1599-6
chicago: Fleischer, Jason G., Roberta Schulte, Hsiao H. Tsai, Swati Tyagi, Arkaitz
Ibarra, Maxim N. Shokhirev, Ling Huang, Martin Hetzer, and Saket Navlakha. “Predicting
Age from the Transcriptome of Human Dermal Fibroblasts.” Genome Biology.
BioMed Central, 2018. https://doi.org/10.1186/s13059-018-1599-6.
ieee: J. G. Fleischer et al., “Predicting age from the transcriptome of human
dermal fibroblasts,” Genome Biology, vol. 19. BioMed Central, 2018.
ista: Fleischer JG, Schulte R, Tsai HH, Tyagi S, Ibarra A, Shokhirev MN, Huang L,
Hetzer M, Navlakha S. 2018. Predicting age from the transcriptome of human dermal
fibroblasts. Genome Biology. 19, 221.
mla: Fleischer, Jason G., et al. “Predicting Age from the Transcriptome of Human
Dermal Fibroblasts.” Genome Biology, vol. 19, 221, BioMed Central, 2018,
doi:10.1186/s13059-018-1599-6.
short: J.G. Fleischer, R. Schulte, H.H. Tsai, S. Tyagi, A. Ibarra, M.N. Shokhirev,
L. Huang, M. Hetzer, S. Navlakha, Genome Biology 19 (2018).
date_created: 2022-04-07T07:45:40Z
date_published: 2018-12-20T00:00:00Z
date_updated: 2022-07-18T08:32:34Z
day: '20'
doi: 10.1186/s13059-018-1599-6
extern: '1'
external_id:
pmid:
- '30567591'
intvolume: ' 19'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1186/s13059-018-1599-6
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology
publication_identifier:
issn:
- 1474-760X
publication_status: published
publisher: BioMed Central
quality_controlled: '1'
scopus_import: '1'
status: public
title: Predicting age from the transcriptome of human dermal fibroblasts
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 19
year: '2018'
...
---
_id: '9506'
abstract:
- lang: eng
text: Methylation in the bodies of active genes is common in animals and vascular
plants. Evolutionary patterns indicate homeostatic functions for this type of
methylation.
article_number: '87'
article_processing_charge: No
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Zilberman D. An evolutionary case for functional gene body methylation in plants
and animals. Genome Biology. 2017;18(1). doi:10.1186/s13059-017-1230-2
apa: Zilberman, D. (2017). An evolutionary case for functional gene body methylation
in plants and animals. Genome Biology. Springer Nature. https://doi.org/10.1186/s13059-017-1230-2
chicago: Zilberman, Daniel. “An Evolutionary Case for Functional Gene Body Methylation
in Plants and Animals.” Genome Biology. Springer Nature, 2017. https://doi.org/10.1186/s13059-017-1230-2.
ieee: D. Zilberman, “An evolutionary case for functional gene body methylation in
plants and animals,” Genome Biology, vol. 18, no. 1. Springer Nature, 2017.
ista: Zilberman D. 2017. An evolutionary case for functional gene body methylation
in plants and animals. Genome Biology. 18(1), 87.
mla: Zilberman, Daniel. “An Evolutionary Case for Functional Gene Body Methylation
in Plants and Animals.” Genome Biology, vol. 18, no. 1, 87, Springer Nature,
2017, doi:10.1186/s13059-017-1230-2.
short: D. Zilberman, Genome Biology 18 (2017).
date_created: 2021-06-07T12:27:39Z
date_published: 2017-05-09T00:00:00Z
date_updated: 2021-12-14T07:55:02Z
day: '09'
ddc:
- '570'
department:
- _id: DaZi
doi: 10.1186/s13059-017-1230-2
extern: '1'
external_id:
pmid:
- '28486944'
file:
- access_level: open_access
checksum: 5a455ad914e7d225b1baa4ab07fd925e
content_type: application/pdf
creator: asandaue
date_created: 2021-06-07T12:31:36Z
date_updated: 2021-06-07T12:31:36Z
file_id: '9507'
file_name: 2017_GenomeBiology_Zilberman.pdf
file_size: 278183
relation: main_file
success: 1
file_date_updated: 2021-06-07T12:31:36Z
has_accepted_license: '1'
intvolume: ' 18'
issue: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology
publication_identifier:
eissn:
- 1465-6906
issn:
- 1474-760X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: An evolutionary case for functional gene body methylation in plants and animals
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 18
year: '2017'
...
---
_id: '9514'
abstract:
- lang: eng
text: "Background:\r\nDNA methylation occurs at preferred sites in eukaryotes. In
Arabidopsis, DNA cytosine methylation is maintained by three subfamilies of methyltransferases
with distinct substrate specificities and different modes of action. Targeting
of cytosine methylation at selected loci has been found to sometimes involve histone
H3 methylation and small interfering (si)RNAs. However, the relationship between
different cytosine methylation pathways and their preferred targets is not known.\r\nResults:\r\nWe
used a microarray-based profiling method to explore the involvement of Arabidopsis
CMT3 and DRM DNA methyltransferases, a histone H3 lysine-9 methyltransferase (KYP)
and an Argonaute-related siRNA silencing component (AGO4) in methylating target
loci. We found that KYP targets are also CMT3 targets, suggesting that histone
methylation maintains CNG methylation genome-wide. CMT3 and KYP targets show similar
proximal distributions that correspond to the overall distribution of transposable
elements of all types, whereas DRM targets are distributed more distally along
the chromosome. We find an inverse relationship between element size and loss
of methylation in ago4 and drm mutants.\r\nConclusion:\r\nWe conclude that the
targets of both DNA methylation and histone H3K9 methylation pathways are transposable
elements genome-wide, irrespective of element type and position. Our findings
also suggest that RNA-directed DNA methylation is required to silence isolated
elements that may be too small to be maintained in a silent state by a chromatin-based
mechanism alone. Thus, parallel pathways would be needed to maintain silencing
of transposable elements."
article_number: R90
article_processing_charge: No
article_type: original
author:
- first_name: Robert K.
full_name: Tran, Robert K.
last_name: Tran
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Cecilia
full_name: de Bustos, Cecilia
last_name: de Bustos
- first_name: Renata F.
full_name: Ditt, Renata F.
last_name: Ditt
- first_name: Jorja G.
full_name: Henikoff, Jorja G.
last_name: Henikoff
- first_name: Anders M.
full_name: Lindroth, Anders M.
last_name: Lindroth
- first_name: Jeffrey
full_name: Delrow, Jeffrey
last_name: Delrow
- first_name: Tom
full_name: Boyle, Tom
last_name: Boyle
- first_name: Samson
full_name: Kwong, Samson
last_name: Kwong
- first_name: Terri D.
full_name: Bryson, Terri D.
last_name: Bryson
- first_name: Steven E.
full_name: Jacobsen, Steven E.
last_name: Jacobsen
- first_name: Steven
full_name: Henikoff, Steven
last_name: Henikoff
citation:
ama: Tran RK, Zilberman D, de Bustos C, et al. Chromatin and siRNA pathways cooperate
to maintain DNA methylation of small transposable elements in Arabidopsis. Genome
Biology. 2005;6(11). doi:10.1186/gb-2005-6-11-r90
apa: Tran, R. K., Zilberman, D., de Bustos, C., Ditt, R. F., Henikoff, J. G., Lindroth,
A. M., … Henikoff, S. (2005). Chromatin and siRNA pathways cooperate to maintain
DNA methylation of small transposable elements in Arabidopsis. Genome Biology.
Springer Nature. https://doi.org/10.1186/gb-2005-6-11-r90
chicago: Tran, Robert K., Daniel Zilberman, Cecilia de Bustos, Renata F. Ditt, Jorja
G. Henikoff, Anders M. Lindroth, Jeffrey Delrow, et al. “Chromatin and SiRNA Pathways
Cooperate to Maintain DNA Methylation of Small Transposable Elements in Arabidopsis.”
Genome Biology. Springer Nature, 2005. https://doi.org/10.1186/gb-2005-6-11-r90.
ieee: R. K. Tran et al., “Chromatin and siRNA pathways cooperate to maintain
DNA methylation of small transposable elements in Arabidopsis,” Genome Biology,
vol. 6, no. 11. Springer Nature, 2005.
ista: Tran RK, Zilberman D, de Bustos C, Ditt RF, Henikoff JG, Lindroth AM, Delrow
J, Boyle T, Kwong S, Bryson TD, Jacobsen SE, Henikoff S. 2005. Chromatin and siRNA
pathways cooperate to maintain DNA methylation of small transposable elements
in Arabidopsis. Genome Biology. 6(11), R90.
mla: Tran, Robert K., et al. “Chromatin and SiRNA Pathways Cooperate to Maintain
DNA Methylation of Small Transposable Elements in Arabidopsis.” Genome Biology,
vol. 6, no. 11, R90, Springer Nature, 2005, doi:10.1186/gb-2005-6-11-r90.
short: R.K. Tran, D. Zilberman, C. de Bustos, R.F. Ditt, J.G. Henikoff, A.M. Lindroth,
J. Delrow, T. Boyle, S. Kwong, T.D. Bryson, S.E. Jacobsen, S. Henikoff, Genome
Biology 6 (2005).
date_created: 2021-06-07T13:12:41Z
date_published: 2005-10-19T00:00:00Z
date_updated: 2021-12-14T09:09:41Z
day: '19'
department:
- _id: DaZi
doi: 10.1186/gb-2005-6-11-r90
extern: '1'
external_id:
pmid:
- '16277745'
intvolume: ' 6'
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1186/gb-2005-6-11-r90
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology
publication_identifier:
eissn:
- 1465-6906
issn:
- 1474-760X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chromatin and siRNA pathways cooperate to maintain DNA methylation of small
transposable elements in Arabidopsis
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 6
year: '2005'
...
---
_id: '9511'
abstract:
- lang: eng
text: Recent progress in understanding the silencing of transposable elements in
the model plant Arabidopsis has revealed an interplay between DNA methylation,
histone methylation and small interfering RNAs. DNA and histone methylation are
not always sufficient to maintain silencing, and RNA-based reinforcement can be
needed to maintain as well as initiate it.
article_number: '249'
article_processing_charge: No
article_type: review
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Steven
full_name: Henikoff, Steven
last_name: Henikoff
citation:
ama: 'Zilberman D, Henikoff S. Silencing of transposons in plant genomes: kick them
when they’re down. Genome Biology. 2004;5(12). doi:10.1186/gb-2004-5-12-249'
apa: 'Zilberman, D., & Henikoff, S. (2004). Silencing of transposons in plant
genomes: kick them when they’re down. Genome Biology. Springer Nature.
https://doi.org/10.1186/gb-2004-5-12-249'
chicago: 'Zilberman, Daniel, and Steven Henikoff. “Silencing of Transposons in Plant
Genomes: Kick Them When They’re Down.” Genome Biology. Springer Nature,
2004. https://doi.org/10.1186/gb-2004-5-12-249.'
ieee: 'D. Zilberman and S. Henikoff, “Silencing of transposons in plant genomes:
kick them when they’re down,” Genome Biology, vol. 5, no. 12. Springer
Nature, 2004.'
ista: 'Zilberman D, Henikoff S. 2004. Silencing of transposons in plant genomes:
kick them when they’re down. Genome Biology. 5(12), 249.'
mla: 'Zilberman, Daniel, and Steven Henikoff. “Silencing of Transposons in Plant
Genomes: Kick Them When They’re Down.” Genome Biology, vol. 5, no. 12,
249, Springer Nature, 2004, doi:10.1186/gb-2004-5-12-249.'
short: D. Zilberman, S. Henikoff, Genome Biology 5 (2004).
date_created: 2021-06-07T12:58:06Z
date_published: 2004-11-16T00:00:00Z
date_updated: 2021-12-14T08:44:24Z
day: '16'
department:
- _id: DaZi
doi: 10.1186/gb-2004-5-12-249
extern: '1'
external_id:
pmid:
- '15575975'
intvolume: ' 5'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1186/gb-2004-5-12-249
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology
publication_identifier:
eissn:
- 1465-6906
issn:
- 1474-760X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Silencing of transposons in plant genomes: kick them when they''re down'
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 5
year: '2004'
...