@article{11059,
  abstract     = {The genome is packaged and organized nonrandomly within the 3D space of the nucleus to promote efficient gene expression and to faithfully maintain silencing of heterochromatin. The genome is enclosed within the nucleus by the nuclear envelope membrane, which contains a set of proteins that actively participate in chromatin organization and gene regulation. Technological advances are providing views of genome organization at unprecedented resolution and are beginning to reveal the ways that cells co-opt the structures of the nuclear periphery for nuclear organization and gene regulation. These genome regulatory roles of proteins of the nuclear periphery have important influences on development, disease and ageing.},
  author       = {Buchwalter, Abigail and Kaneshiro, Jeanae M. and HETZER, Martin W},
  issn         = {1471-0064},
  journal      = {Nature Reviews Genetics},
  keywords     = {Genetics (clinical), Genetics, Molecular Biology},
  number       = {1},
  pages        = {39--50},
  publisher    = {Springer Nature},
  title        = {{Coaching from the sidelines: The nuclear periphery in genome regulation}},
  doi          = {10.1038/s41576-018-0063-5},
  volume       = {20},
  year         = {2019},
}

@article{4261,
  abstract     = {Until recently, it was impracticable to identify the genes that are responsible for variation in continuous traits, or to directly observe the effects of their different alleles. Now, the abundance of genetic markers has made it possible to identify quantitative trait loci (QTL) — the regions of a chromosome or, ideally, individual sequence variants that are responsible for trait variation. What kind of QTL do we expect to find and what can our observations of QTL tell us about how organisms evolve? The key to understanding the evolutionary significance of QTL is to understand the nature of inherited variation, not in the immediate mechanistic sense of how genes influence phenotype, but, rather, to know what evolutionary forces maintain genetic variability.},
  author       = {Barton, Nicholas H and Keightley, Peter},
  issn         = {1471-0056},
  journal      = {Nature Reviews Genetics},
  pages        = {11 -- 21},
  publisher    = {Nature Publishing Group},
  title        = {{Understanding quantitative genetic variation}},
  doi          = {10.1038/nrg700},
  volume       = {3},
  year         = {2002},
}