@article{12162,
  abstract     = {Homeostatic balance in the intestinal epithelium relies on a fast cellular turnover, which is coordinated by an intricate interplay between biochemical signalling, mechanical forces and organ geometry. We review recent modelling approaches that have been developed to understand different facets of this remarkable homeostatic equilibrium. Existing models offer different, albeit complementary, perspectives on the problem. First, biomechanical models aim to explain the local and global mechanical stresses driving cell renewal as well as tissue shape maintenance. Second, compartmental models provide insights into the conditions necessary to keep a constant flow of cells with well-defined ratios of cell types, and how perturbations can lead to an unbalance of relative compartment sizes. A third family of models address, at the cellular level, the nature and regulation of stem fate choices that are necessary to fuel cellular turnover. We also review how these different approaches are starting to be integrated together across scales, to provide quantitative predictions and new conceptual frameworks to think about the dynamics of cell renewal in complex tissues.},
  author       = {Corominas-Murtra, Bernat and Hannezo, Edouard B},
  issn         = {1084-9521},
  journal      = {Seminars in Cell & Developmental Biology},
  keywords     = {Cell Biology, Developmental Biology},
  pages        = {58--65},
  publisher    = {Elsevier},
  title        = {{Modelling the dynamics of mammalian gut homeostasis}},
  doi          = {10.1016/j.semcdb.2022.11.005},
  volume       = {150-151},
  year         = {2023},
}

@article{4148,
  abstract     = {Members of the Wnt family have been implicated in a variety of developmental processes including axis formation, Patterning of the central nervous system and tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway similar to that involved in the establishment of planar cell polarity in Drosophila regulates convergent extension movements during zebrafish and Xenopus gastrulation. This finding provides a good starting point to dissect the complex cell biology and genetic regulation of vertebrate gastrulation movements.},
  author       = {Tada, Masazumi and Concha, Miguel and Heisenberg, Carl-Philipp J},
  issn         = {1084-9521},
  journal      = {Seminars in Cell & Developmental Biology},
  number       = {3},
  pages        = {251 -- 260},
  publisher    = {Academic Press},
  title        = {{Non-canonical Wnt signalling and regulation of gastrulation movements}},
  doi          = {10.1016/S1084-9521(02)00052-6},
  volume       = {13},
  year         = {2002},
}

@article{4196,
  abstract     = {During vertebrate gastrulation, large cellular rearrangements lead to the formation of the three germ layers, ectoderm, mesoderm and endoderm. Zebrafish offer many genetic and experimental advantages for studying vertebrate gastrulation movements. For instance, several mutants, including silberblick, knypek and trilobite, exhibit defects in morphogenesis during gastrulation. The identification of the genes mutated in these lines together with the analysis of the mutant phenotypes has provided new insights into the molecular and cellular mechanisms that underlie vertebrate gastrulation movements.},
  author       = {Heisenberg, Carl-Philipp J and Tada, Masazumi},
  issn         = {1084-9521},
  journal      = {Seminars in Cell & Developmental Biology},
  number       = {6},
  pages        = {471 -- 479},
  publisher    = {Academic Press},
  title        = {{Zebrafish gastrulation movements: bridging cell and developmental biology}},
  doi          = {10.1016/S1084952102001003},
  volume       = {13},
  year         = {2002},
}