---
_id: '709'
abstract:
- lang: eng
  text: Adipose tissues play key roles in energy homeostasis. Brown adipocytes and
    beige adipocytes in white adipose tissue (WAT) share the similar characters of
    thermogenesis, both of them could be potential targets for obesity management.
    Several thermo-sensitive transient receptor potential channels (thermoTRPs) are
    shown to be involved in adipocyte biology. However, the expression pattern of
    thermoTRPs in adipose tissues from obese mice is still unknown. The mRNA expression
    of thermoTRPs in subcutaneous WAT (sWAT) and interscapular brown adipose tissue
    (iBAT) from lean and obese mice were measured using reverse transcriptase-quantitative
    PCRs (RT-qPCR). The results demonstrated that all 10 thermoTRPs are expressed
    in both iBAT and sWAT, and without significant difference in the mRNA expression
    level of thermoTRPs between these two tissues. Moreover, Trpv1 and Trpv3 mRNA
    expression levels in both iBAT and sWAT were significantly decreased in high fat
    diet (HFD)-induced obese mice and db/db (leptin receptor deficient) mice. Trpm2
    mRNA expression level was significantly decreased only in sWAT from HFD-induced
    obese mice and db/db mice. On the other hand, Trpv2 and Trpv4 mRNA expression
    levels in iBAT and sWAT were significantly increased in HFD-induced obese mice
    and db/db mice. Taken together, we conclude that all 10 thermoTRPs are expressed
    in iBAT and sWAT. And several thermoTRPs differentially expressed in adipose tissues
    from HFD-induced obese mice and db/db mice, suggesting a potential involvement
    in anti-obesity regulations.
author:
- first_name: Wuping
  full_name: Sun, Wuping
  last_name: Sun
- first_name: Chen
  full_name: Li, Chen
  last_name: Li
- first_name: Yonghong
  full_name: Zhang, Yonghong
  last_name: Zhang
- first_name: Changyu
  full_name: Jiang, Changyu
  last_name: Jiang
- first_name: Ming-Zhu
  full_name: Zhai, Ming-Zhu
  id: 34009CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Zhai
- first_name: Qian
  full_name: Zhou, Qian
  last_name: Zhou
- first_name: Lizu
  full_name: Xiao, Lizu
  last_name: Xiao
- first_name: Qiwen
  full_name: Deng, Qiwen
  last_name: Deng
citation:
  ama: Sun W, Li C, Zhang Y, et al. Gene expression changes of thermo sensitive transient
    receptor potential channels in obese mice. <i>Cell Biology International</i>.
    2017;41(8):908-913. doi:<a href="https://doi.org/10.1002/cbin.10783">10.1002/cbin.10783</a>
  apa: Sun, W., Li, C., Zhang, Y., Jiang, C., Zhai, M.-Z., Zhou, Q., … Deng, Q. (2017).
    Gene expression changes of thermo sensitive transient receptor potential channels
    in obese mice. <i>Cell Biology International</i>. Wiley-Blackwell. <a href="https://doi.org/10.1002/cbin.10783">https://doi.org/10.1002/cbin.10783</a>
  chicago: Sun, Wuping, Chen Li, Yonghong Zhang, Changyu Jiang, Ming-Zhu Zhai, Qian
    Zhou, Lizu Xiao, and Qiwen Deng. “Gene Expression Changes of Thermo Sensitive
    Transient Receptor Potential Channels in Obese Mice.” <i>Cell Biology International</i>.
    Wiley-Blackwell, 2017. <a href="https://doi.org/10.1002/cbin.10783">https://doi.org/10.1002/cbin.10783</a>.
  ieee: W. Sun <i>et al.</i>, “Gene expression changes of thermo sensitive transient
    receptor potential channels in obese mice,” <i>Cell Biology International</i>,
    vol. 41, no. 8. Wiley-Blackwell, pp. 908–913, 2017.
  ista: Sun W, Li C, Zhang Y, Jiang C, Zhai M-Z, Zhou Q, Xiao L, Deng Q. 2017. Gene
    expression changes of thermo sensitive transient receptor potential channels in
    obese mice. Cell Biology International. 41(8), 908–913.
  mla: Sun, Wuping, et al. “Gene Expression Changes of Thermo Sensitive Transient
    Receptor Potential Channels in Obese Mice.” <i>Cell Biology International</i>,
    vol. 41, no. 8, Wiley-Blackwell, 2017, pp. 908–13, doi:<a href="https://doi.org/10.1002/cbin.10783">10.1002/cbin.10783</a>.
  short: W. Sun, C. Li, Y. Zhang, C. Jiang, M.-Z. Zhai, Q. Zhou, L. Xiao, Q. Deng,
    Cell Biology International 41 (2017) 908–913.
date_created: 2018-12-11T11:48:04Z
date_published: 2017-08-01T00:00:00Z
date_updated: 2021-01-12T08:11:47Z
day: '01'
department:
- _id: RySh
doi: 10.1002/cbin.10783
intvolume: '        41'
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
page: 908 - 913
publication: Cell Biology International
publication_identifier:
  issn:
  - '10656995'
publication_status: published
publisher: Wiley-Blackwell
publist_id: '6981'
quality_controlled: '1'
scopus_import: 1
status: public
title: Gene expression changes of thermo sensitive transient receptor potential channels
  in obese mice
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 41
year: '2017'
...