[{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"volume":79,"file_date_updated":"2023-08-16T12:29:06Z","oa":1,"publication_status":"published","_id":"12679","abstract":[{"lang":"eng","text":"How to generate a brain of correct size and with appropriate cell-type diversity during development is a major question in Neuroscience. In the developing neocortex, radial glial progenitor (RGP) cells are the main neural stem cells that produce cortical excitatory projection neurons, glial cells, and establish the prospective postnatal stem cell niche in the lateral ventricles. RGPs follow a tightly orchestrated developmental program that when disrupted can result in severe cortical malformations such as microcephaly and megalencephaly. The precise cellular and molecular mechanisms instructing faithful RGP lineage progression are however not well understood. This review will summarize recent conceptual advances that contribute to our understanding of the general principles of RGP lineage progression."}],"date_published":"2023-04-01T00:00:00Z","article_number":"102695","file":[{"creator":"dernst","file_size":1787894,"file_name":"2023_CurrentOpinionNeurobio_Hippenmeyer.pdf","access_level":"open_access","date_updated":"2023-08-16T12:29:06Z","checksum":"4d11c4ca87e6cbc4d2ac46d3225ea615","relation":"main_file","file_id":"14071","content_type":"application/pdf","success":1,"date_created":"2023-08-16T12:29:06Z"}],"article_processing_charge":"Yes (via OA deal)","issue":"4","publication_identifier":{"issn":["0959-4388"]},"external_id":{"isi":["000953497700001"],"pmid":["36842274"]},"scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2023-08-16T12:30:25Z","has_accepted_license":"1","year":"2023","oa_version":"Published Version","article_type":"review","status":"public","intvolume":"        79","publication":"Current Opinion in Neurobiology","department":[{"_id":"SiHi"}],"quality_controlled":"1","isi":1,"publisher":"Elsevier","date_created":"2023-02-26T12:24:21Z","month":"04","doi":"10.1016/j.conb.2023.102695","ddc":["570"],"keyword":["General Neuroscience"],"language":[{"iso":"eng"}],"project":[{"grant_number":"F07805","name":"Molecular Mechanisms of Neural Stem Cell Lineage Progression","_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E"},{"call_identifier":"H2020","_id":"260018B0-B435-11E9-9278-68D0E5697425","grant_number":"725780","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development"}],"pmid":1,"acknowledgement":"I wish to thank all current and past members of the Hippenmeyer laboratory at ISTA for exciting discussions on the subject of this review. I apologize to colleagues whose work I could not cite and/or discuss in the frame of the available space. Work in the Hippenmeyer laboratory on the\r\ndiscussed topic is supported by ISTA institutional funds, FWF SFB F78 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Programme (grant agree-ment no. 725780 LinPro) to SH.","type":"journal_article","author":[{"full_name":"Hippenmeyer, Simon","first_name":"Simon","last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061"}],"day":"01","title":"Principles of neural stem cell lineage progression: Insights from developing cerebral cortex","citation":{"mla":"Hippenmeyer, Simon. “Principles of Neural Stem Cell Lineage Progression: Insights from Developing Cerebral Cortex.” <i>Current Opinion in Neurobiology</i>, vol. 79, no. 4, 102695, Elsevier, 2023, doi:<a href=\"https://doi.org/10.1016/j.conb.2023.102695\">10.1016/j.conb.2023.102695</a>.","ista":"Hippenmeyer S. 2023. Principles of neural stem cell lineage progression: Insights from developing cerebral cortex. Current Opinion in Neurobiology. 79(4), 102695.","ieee":"S. Hippenmeyer, “Principles of neural stem cell lineage progression: Insights from developing cerebral cortex,” <i>Current Opinion in Neurobiology</i>, vol. 79, no. 4. Elsevier, 2023.","chicago":"Hippenmeyer, Simon. “Principles of Neural Stem Cell Lineage Progression: Insights from Developing Cerebral Cortex.” <i>Current Opinion in Neurobiology</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.conb.2023.102695\">https://doi.org/10.1016/j.conb.2023.102695</a>.","apa":"Hippenmeyer, S. (2023). Principles of neural stem cell lineage progression: Insights from developing cerebral cortex. <i>Current Opinion in Neurobiology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.conb.2023.102695\">https://doi.org/10.1016/j.conb.2023.102695</a>","ama":"Hippenmeyer S. Principles of neural stem cell lineage progression: Insights from developing cerebral cortex. <i>Current Opinion in Neurobiology</i>. 2023;79(4). doi:<a href=\"https://doi.org/10.1016/j.conb.2023.102695\">10.1016/j.conb.2023.102695</a>","short":"S. Hippenmeyer, Current Opinion in Neurobiology 79 (2023)."},"ec_funded":1},{"publisher":"Elsevier","publication_status":"published","publication":"Current Opinion in Neurobiology","quality_controlled":"1","intvolume":"        43","status":"public","volume":43,"page":"A1-A5","article_processing_charge":"No","month":"04","extern":"1","abstract":[{"text":"Synaptic plasticity is essential for the function of neural systems. It sets up initial circuitry and adjusts connection strengths according to the maintenance requirements of its host networks. Like all things biological, synaptic plasticity must rely on genetic programs to provide the molecular components of its machinery to integrate ongoing, often multi-sensory experience without destabilising effects. Because of its fundamental importance to healthy behaviour, understanding plasticity is thought to hold the key to understanding the brain. There are innumerable ways to approach this topic and a complete review of its status quo would be impossible. In the current issue we dig into some of the finer points of synaptic plasticity, starting small, at the level of genes, and slowly zooming out to synapses, populations of synapses, and finally entire systems and brain regions. At each level, we tried to represent different perspectives, different systems, and approaches to the same questions to give a broad sampling of how synaptic plasticity is being studied.","lang":"eng"}],"_id":"8019","date_published":"2017-04-17T00:00:00Z","date_created":"2020-06-25T13:03:30Z","pmid":1,"external_id":{"pmid":["28427877"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T08:16:33Z","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0959-4388"]},"doi":"10.1016/j.conb.2017.04.002","citation":{"mla":"Vogels, Tim P., and Leslie C. Griffith. “Editorial Overview: Neurobiology of Learning and Plasticity 2017.” <i>Current Opinion in Neurobiology</i>, vol. 43, Elsevier, 2017, pp. A1–5, doi:<a href=\"https://doi.org/10.1016/j.conb.2017.04.002\">10.1016/j.conb.2017.04.002</a>.","ista":"Vogels TP, Griffith LC. 2017. Editorial overview: Neurobiology of learning and plasticity 2017. Current Opinion in Neurobiology. 43, A1–A5.","ieee":"T. P. Vogels and L. C. Griffith, “Editorial overview: Neurobiology of learning and plasticity 2017,” <i>Current Opinion in Neurobiology</i>, vol. 43. Elsevier, pp. A1–A5, 2017.","chicago":"Vogels, Tim P, and Leslie C Griffith. “Editorial Overview: Neurobiology of Learning and Plasticity 2017.” <i>Current Opinion in Neurobiology</i>. Elsevier, 2017. <a href=\"https://doi.org/10.1016/j.conb.2017.04.002\">https://doi.org/10.1016/j.conb.2017.04.002</a>.","apa":"Vogels, T. P., &#38; Griffith, L. C. (2017). Editorial overview: Neurobiology of learning and plasticity 2017. <i>Current Opinion in Neurobiology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.conb.2017.04.002\">https://doi.org/10.1016/j.conb.2017.04.002</a>","ama":"Vogels TP, Griffith LC. Editorial overview: Neurobiology of learning and plasticity 2017. <i>Current Opinion in Neurobiology</i>. 2017;43:A1-A5. doi:<a href=\"https://doi.org/10.1016/j.conb.2017.04.002\">10.1016/j.conb.2017.04.002</a>","short":"T.P. Vogels, L.C. Griffith, Current Opinion in Neurobiology 43 (2017) A1–A5."},"title":"Editorial overview: Neurobiology of learning and plasticity 2017","article_type":"letter_note","day":"17","type":"journal_article","author":[{"full_name":"Vogels, Tim P","first_name":"Tim P","last_name":"Vogels","id":"CB6FF8D2-008F-11EA-8E08-2637E6697425","orcid":"0000-0003-3295-6181"},{"first_name":"Leslie C","full_name":"Griffith, Leslie C","last_name":"Griffith"}],"oa_version":"None","year":"2017"},{"author":[{"first_name":"Lora Beatrice Jaeger","full_name":"Sweeney, Lora Beatrice Jaeger","last_name":"Sweeney","id":"56BE8254-C4F0-11E9-8E45-0B23E6697425","orcid":"0000-0001-9242-5601"},{"last_name":"Kelley","full_name":"Kelley, Darcy B","first_name":"Darcy B"}],"type":"journal_article","oa_version":"None","year":"2014","article_type":"original","day":"01","title":"Harnessing vocal patterns for social communication","citation":{"chicago":"Sweeney, Lora B., and Darcy B Kelley. “Harnessing Vocal Patterns for Social Communication.” <i>Current Opinion in Neurobiology</i>. Elsevier, 2014. <a href=\"https://doi.org/10.1016/j.conb.2014.06.006\">https://doi.org/10.1016/j.conb.2014.06.006</a>.","ieee":"L. B. Sweeney and D. B. Kelley, “Harnessing vocal patterns for social communication,” <i>Current Opinion in Neurobiology</i>, vol. 28, no. 10. Elsevier, pp. 34–41, 2014.","ista":"Sweeney LB, Kelley DB. 2014. Harnessing vocal patterns for social communication. Current Opinion in Neurobiology. 28(10), 34–41.","mla":"Sweeney, Lora B., and Darcy B. Kelley. “Harnessing Vocal Patterns for Social Communication.” <i>Current Opinion in Neurobiology</i>, vol. 28, no. 10, Elsevier, 2014, pp. 34–41, doi:<a href=\"https://doi.org/10.1016/j.conb.2014.06.006\">10.1016/j.conb.2014.06.006</a>.","short":"L.B. Sweeney, D.B. Kelley, Current Opinion in Neurobiology 28 (2014) 34–41.","ama":"Sweeney LB, Kelley DB. Harnessing vocal patterns for social communication. <i>Current Opinion in Neurobiology</i>. 2014;28(10):34-41. doi:<a href=\"https://doi.org/10.1016/j.conb.2014.06.006\">10.1016/j.conb.2014.06.006</a>","apa":"Sweeney, L. B., &#38; Kelley, D. B. (2014). Harnessing vocal patterns for social communication. <i>Current Opinion in Neurobiology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.conb.2014.06.006\">https://doi.org/10.1016/j.conb.2014.06.006</a>"},"publication_identifier":{"issn":["0959-4388"]},"doi":"10.1016/j.conb.2014.06.006","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"date_updated":"2024-01-31T10:14:08Z","_id":"7699","date_created":"2020-04-30T10:35:39Z","date_published":"2014-10-01T00:00:00Z","month":"10","extern":"1","article_processing_charge":"No","issue":"10","page":"34-41","status":"public","intvolume":"        28","volume":28,"publication":"Current Opinion in Neurobiology","quality_controlled":"1","publisher":"Elsevier","publication_status":"published"},{"publist_id":"2927","article_type":"original","year":"1994","oa_version":"None","date_updated":"2022-06-03T11:26:52Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","external_id":{"pmid":["7522678 "]},"scopus_import":"1","publication_identifier":{"issn":["0959-4388"]},"_id":"3460","date_published":"1994-06-01T00:00:00Z","abstract":[{"lang":"eng","text":"Excitatory postsynaptic currents in neurones of the central nervous system have a dual-component time course that results from the co-activation of AMPA/kainate-type and NMDA-type glutamate receptors. New approaches in electrophysiology and molecular biology have provided a better understanding of the factors that determine the kinectics of excitatory postsynaptic currents. Recent studies suggest that the time course of neurotransmitter concentration in the synaptic cleft, the gating properties of the native channels, and the glutamate receptor subunit composition all appear to be important factors."}],"issue":"3","article_processing_charge":"No","volume":4,"publication_status":"published","main_file_link":[{"url":"https://www.sciencedirect.com/science/article/pii/0959438894900981?via%3Dihub"}],"day":"01","type":"journal_article","author":[{"full_name":"Jonas, Peter M","first_name":"Peter M","last_name":"Jonas","orcid":"0000-0001-5001-4804","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Nelson","full_name":"Spruston, Nelson","last_name":"Spruston"}],"citation":{"short":"P.M. Jonas, N. Spruston, Current Opinion in Neurobiology 4 (1994) 366–372.","apa":"Jonas, P. M., &#38; Spruston, N. (1994). Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. <i>Current Opinion in Neurobiology</i>. Elsevier. <a href=\"https://doi.org/10.1016/0959-4388(94)90098-1\">https://doi.org/10.1016/0959-4388(94)90098-1</a>","ama":"Jonas PM, Spruston N. Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. <i>Current Opinion in Neurobiology</i>. 1994;4(3):366-372. doi:<a href=\"https://doi.org/10.1016/0959-4388(94)90098-1\">10.1016/0959-4388(94)90098-1</a>","ieee":"P. M. Jonas and N. Spruston, “Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS,” <i>Current Opinion in Neurobiology</i>, vol. 4, no. 3. Elsevier, pp. 366–372, 1994.","ista":"Jonas PM, Spruston N. 1994. Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. Current Opinion in Neurobiology. 4(3), 366–372.","chicago":"Jonas, Peter M, and Nelson Spruston. “Mechanisms Shaping Glutamate-Mediated Excitatory Postsynaptic Currents in the CNS.” <i>Current Opinion in Neurobiology</i>. Elsevier, 1994. <a href=\"https://doi.org/10.1016/0959-4388(94)90098-1\">https://doi.org/10.1016/0959-4388(94)90098-1</a>.","mla":"Jonas, Peter M., and Nelson Spruston. “Mechanisms Shaping Glutamate-Mediated Excitatory Postsynaptic Currents in the CNS.” <i>Current Opinion in Neurobiology</i>, vol. 4, no. 3, Elsevier, 1994, pp. 366–72, doi:<a href=\"https://doi.org/10.1016/0959-4388(94)90098-1\">10.1016/0959-4388(94)90098-1</a>."},"title":"Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS","language":[{"iso":"eng"}],"doi":"10.1016/0959-4388(94)90098-1","acknowledgement":"We thank JGG Borst, N Burnashev, M Häusser, G Stuart and A Viilarroel for critically reading the manuscript and E von Kitzing and A Roth for doing the simulations and for many helpful discussions. Supported by the Deutsche Forschungsgemeinschaft (SFB 317-B14) and the Alexander von Humboldt Foundation. ","pmid":1,"extern":"1","month":"06","date_created":"2018-12-11T12:03:27Z","page":"366 - 372","quality_controlled":"1","publication":"Current Opinion in Neurobiology","status":"public","intvolume":"         4","publisher":"Elsevier"}]