---
_id: '11988'
abstract:
- lang: eng
text: A continuous Bucherer–Bergs hydantoin synthesis utilizing intensified conditions
is reported. The methodology is characterized by a two-feed flow approach to independently
feed the organic substrate and the aqueous reagent solution. The increased interfacial
area of the biphasic reaction mixture and the lack of headspace enabled almost
quantitative conversions within ca. 30 minutes at 120 °C and 20 bar even for unpolar
starting materials. In addition, a selective N(3)-monoalkylation of the resulting
heterocycles under batch microwave conditions is reported yielding potential acetylcholinesterase
inhibitors.
article_processing_charge: No
article_type: letter_note
author:
- first_name: C.
full_name: Kappe, C.
last_name: Kappe
- first_name: Julia
full_name: Monteiro, Julia
last_name: Monteiro
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Arlene
full_name: Corrêa, Arlene
last_name: Corrêa
citation:
ama: 'Kappe C, Monteiro J, Pieber B, Corrêa A. Continuous synthesis of hydantoins:
Intensifying the Bucherer–Bergs reaction. Synlett. 2016;27(01):83-87. doi:10.1055/s-0035-1560317'
apa: 'Kappe, C., Monteiro, J., Pieber, B., & Corrêa, A. (2016). Continuous synthesis
of hydantoins: Intensifying the Bucherer–Bergs reaction. Synlett. Georg
Thieme Verlag. https://doi.org/10.1055/s-0035-1560317'
chicago: 'Kappe, C., Julia Monteiro, Bartholomäus Pieber, and Arlene Corrêa. “Continuous
Synthesis of Hydantoins: Intensifying the Bucherer–Bergs Reaction.” Synlett.
Georg Thieme Verlag, 2016. https://doi.org/10.1055/s-0035-1560317.'
ieee: 'C. Kappe, J. Monteiro, B. Pieber, and A. Corrêa, “Continuous synthesis of
hydantoins: Intensifying the Bucherer–Bergs reaction,” Synlett, vol. 27,
no. 01. Georg Thieme Verlag, pp. 83–87, 2016.'
ista: 'Kappe C, Monteiro J, Pieber B, Corrêa A. 2016. Continuous synthesis of hydantoins:
Intensifying the Bucherer–Bergs reaction. Synlett. 27(01), 83–87.'
mla: 'Kappe, C., et al. “Continuous Synthesis of Hydantoins: Intensifying the Bucherer–Bergs
Reaction.” Synlett, vol. 27, no. 01, Georg Thieme Verlag, 2016, pp. 83–87,
doi:10.1055/s-0035-1560317.'
short: C. Kappe, J. Monteiro, B. Pieber, A. Corrêa, Synlett 27 (2016) 83–87.
date_created: 2022-08-25T11:52:22Z
date_published: 2016-01-04T00:00:00Z
date_updated: 2023-02-21T10:10:33Z
day: '04'
doi: 10.1055/s-0035-1560317
extern: '1'
intvolume: ' 27'
issue: '01'
language:
- iso: eng
month: '01'
oa_version: None
page: 83-87
publication: Synlett
publication_identifier:
eissn:
- 1437-2096
issn:
- 0936-5214
publication_status: published
publisher: Georg Thieme Verlag
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Continuous synthesis of hydantoins: Intensifying the Bucherer–Bergs reaction'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 27
year: '2016'
...
---
_id: '13405'
abstract:
- lang: eng
text: We report a method for preparing electrode–molecule–electrode junctions that
incorporate nonsymmetrical azobenzene dithiols. Our approach is based on sequential
deprotection of thiol moieties originally carrying two different protecting groups.
The azobenzene derivatives retained their switching properties within monolayers
and permitted the photocontrol of electrical conductance.
article_processing_charge: No
article_type: original
author:
- first_name: Tal
full_name: Ely, Tal
last_name: Ely
- first_name: Sanjib
full_name: Das, Sanjib
last_name: Das
- first_name: Wenjie
full_name: Li, Wenjie
last_name: Li
- first_name: Pintu
full_name: Kundu, Pintu
last_name: Kundu
- first_name: Einat
full_name: Tirosh, Einat
last_name: Tirosh
- first_name: David
full_name: Cahen, David
last_name: Cahen
- first_name: Ayelet
full_name: Vilan, Ayelet
last_name: Vilan
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Ely T, Das S, Li W, et al. Photocontrol of electrical conductance with a nonsymmetrical
azobenzene dithiol. Synlett. 2013;24(18):2370-2374. doi:10.1055/s-0033-1340087
apa: Ely, T., Das, S., Li, W., Kundu, P., Tirosh, E., Cahen, D., … Klajn, R. (2013).
Photocontrol of electrical conductance with a nonsymmetrical azobenzene dithiol.
Synlett. Georg Thieme Verlag. https://doi.org/10.1055/s-0033-1340087
chicago: Ely, Tal, Sanjib Das, Wenjie Li, Pintu Kundu, Einat Tirosh, David Cahen,
Ayelet Vilan, and Rafal Klajn. “Photocontrol of Electrical Conductance with a
Nonsymmetrical Azobenzene Dithiol.” Synlett. Georg Thieme Verlag, 2013.
https://doi.org/10.1055/s-0033-1340087.
ieee: T. Ely et al., “Photocontrol of electrical conductance with a nonsymmetrical
azobenzene dithiol,” Synlett, vol. 24, no. 18. Georg Thieme Verlag, pp.
2370–2374, 2013.
ista: Ely T, Das S, Li W, Kundu P, Tirosh E, Cahen D, Vilan A, Klajn R. 2013. Photocontrol
of electrical conductance with a nonsymmetrical azobenzene dithiol. Synlett. 24(18),
2370–2374.
mla: Ely, Tal, et al. “Photocontrol of Electrical Conductance with a Nonsymmetrical
Azobenzene Dithiol.” Synlett, vol. 24, no. 18, Georg Thieme Verlag, 2013,
pp. 2370–74, doi:10.1055/s-0033-1340087.
short: T. Ely, S. Das, W. Li, P. Kundu, E. Tirosh, D. Cahen, A. Vilan, R. Klajn,
Synlett 24 (2013) 2370–2374.
date_created: 2023-08-01T09:47:17Z
date_published: 2013-10-22T00:00:00Z
date_updated: 2023-08-08T07:47:35Z
day: '22'
doi: 10.1055/s-0033-1340087
extern: '1'
intvolume: ' 24'
issue: '18'
keyword:
- Organic Chemistry
language:
- iso: eng
month: '10'
oa_version: None
page: 2370-2374
publication: Synlett
publication_identifier:
eissn:
- 1437-2096
issn:
- 0936-5214
publication_status: published
publisher: Georg Thieme Verlag
quality_controlled: '1'
scopus_import: '1'
status: public
title: Photocontrol of electrical conductance with a nonsymmetrical azobenzene dithiol
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2013'
...
---
_id: '13437'
abstract:
- lang: eng
text: Liquid/liquid Phase Transfer Catalysis (PTC) reaction of 4-chlorobutyronitrile
with nonenolisable aldehydes leads via an addition-cyclisation reaction sequence
to derivatives of tetrahydrofuran-3-carbonitrile.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Mieczysław
full_name: Macogonkosza, Mieczysław
last_name: Macogonkosza
- first_name: Jacek
full_name: Przyborowski, Jacek
last_name: Przyborowski
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
- first_name: Andrzej
full_name: Kwast, Andrzej
last_name: Kwast
citation:
ama: Macogonkosza M, Przyborowski J, Klajn R, Kwast A. Simple synthesis of 2-substituted
Tetrahydrofuran-3-carbonitriles. Synlett. 2000;2000(12):1773-1774. doi:10.1055/s-2000-8670
apa: Macogonkosza, M., Przyborowski, J., Klajn, R., & Kwast, A. (2000). Simple
synthesis of 2-substituted Tetrahydrofuran-3-carbonitriles. Synlett. Georg
Thieme Verlag. https://doi.org/10.1055/s-2000-8670
chicago: Macogonkosza, Mieczysław, Jacek Przyborowski, Rafal Klajn, and Andrzej
Kwast. “Simple Synthesis of 2-Substituted Tetrahydrofuran-3-Carbonitriles.” Synlett.
Georg Thieme Verlag, 2000. https://doi.org/10.1055/s-2000-8670.
ieee: M. Macogonkosza, J. Przyborowski, R. Klajn, and A. Kwast, “Simple synthesis
of 2-substituted Tetrahydrofuran-3-carbonitriles,” Synlett, vol. 2000,
no. 12. Georg Thieme Verlag, pp. 1773–1774, 2000.
ista: Macogonkosza M, Przyborowski J, Klajn R, Kwast A. 2000. Simple synthesis of
2-substituted Tetrahydrofuran-3-carbonitriles. Synlett. 2000(12), 1773–1774.
mla: Macogonkosza, Mieczysław, et al. “Simple Synthesis of 2-Substituted Tetrahydrofuran-3-Carbonitriles.”
Synlett, vol. 2000, no. 12, Georg Thieme Verlag, 2000, pp. 1773–74, doi:10.1055/s-2000-8670.
short: M. Macogonkosza, J. Przyborowski, R. Klajn, A. Kwast, Synlett 2000 (2000)
1773–1774.
date_created: 2023-08-01T10:39:48Z
date_published: 2000-12-01T00:00:00Z
date_updated: 2023-08-02T07:54:46Z
day: '01'
doi: 10.1055/s-2000-8670
extern: '1'
intvolume: ' 2000'
issue: '12'
keyword:
- Organic Chemistry
language:
- iso: eng
month: '12'
oa_version: None
page: 1773-1774
publication: Synlett
publication_identifier:
eissn:
- 1437-2096
issn:
- 0936-5214
publication_status: published
publisher: Georg Thieme Verlag
quality_controlled: '1'
scopus_import: '1'
status: public
title: Simple synthesis of 2-substituted Tetrahydrofuran-3-carbonitriles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2000
year: '2000'
...