---
_id: '2558'
abstract:
- lang: eng
  text: Brain areas involved in the genesis and control of daily rhythms receive a
    prominent neural input that contains the neurotransmitter substance P (SP), a
    peptide putatively involved in the synchronization of circadian rhythms by environmental
    light. We investigated the localization of receptors to SP in the suprachiasmatic
    nucleus of the hypothalamus (SCN) and in the intergeniculate leaflet of the thalamus
    (IGL) of the rat and hamster using in situ hybridization histochemistry and immunohistochemistry.
    Consistently with that previously described in the rat, a neuronal population
    distributed along the lateral margin and at the dorso-latero-caudal aspect of
    the hamster SCN expresses moderately the mRNA encoding the SP receptor. In both
    rat and hamster, immunohistochemical data confirm the previous finding and reveal
    an almost complete absence of SP receptors in the ventral part of the SCN, which
    receives a direct projection from the retina. In the IGL of both species, numerous
    neurons prominently express the mRNA encoding the SP receptor. The immunostaining
    shows a high density of SP receptors on perikarya and dendrites throughout the
    nucleus. A dense staining is also observed on individual cells and processes bordering
    the lumen of blood vessels in the SCN and IGL.
article_processing_charge: No
article_type: original
author:
- first_name: Gérard
  full_name: Mick, Gérard
  last_name: Mick
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Kunio
  full_name: Kitahama, Kunio
  last_name: Kitahama
citation:
  ama: Mick G, Shigemoto R, Kitahama K. Localization of substance P receptors in central
    neural structures controlling daily rhythms in nocturnal rodents. <i>Comptes Rendus
    de l’Academie des Sciences - Series III</i>. 1995;318(2):209-217.
  apa: Mick, G., Shigemoto, R., &#38; Kitahama, K. (1995). Localization of substance
    P receptors in central neural structures controlling daily rhythms in nocturnal
    rodents. <i>Comptes Rendus de l’Academie Des Sciences - Series III</i>. Gauthier
    Villars Editeur.
  chicago: Mick, Gérard, Ryuichi Shigemoto, and Kunio Kitahama. “Localization of Substance
    P Receptors in Central Neural Structures Controlling Daily Rhythms in Nocturnal
    Rodents.” <i>Comptes Rendus de l’Academie Des Sciences - Series III</i>. Gauthier
    Villars Editeur, 1995.
  ieee: G. Mick, R. Shigemoto, and K. Kitahama, “Localization of substance P receptors
    in central neural structures controlling daily rhythms in nocturnal rodents,”
    <i>Comptes Rendus de l’Academie des Sciences - Series III</i>, vol. 318, no. 2.
    Gauthier Villars Editeur, pp. 209–217, 1995.
  ista: Mick G, Shigemoto R, Kitahama K. 1995. Localization of substance P receptors
    in central neural structures controlling daily rhythms in nocturnal rodents. Comptes
    Rendus de l’Academie des Sciences - Series III. 318(2), 209–217.
  mla: Mick, Gérard, et al. “Localization of Substance P Receptors in Central Neural
    Structures Controlling Daily Rhythms in Nocturnal Rodents.” <i>Comptes Rendus
    de l’Academie Des Sciences - Series III</i>, vol. 318, no. 2, Gauthier Villars
    Editeur, 1995, pp. 209–17.
  short: G. Mick, R. Shigemoto, K. Kitahama, Comptes Rendus de l’Academie Des Sciences
    - Series III 318 (1995) 209–217.
date_created: 2018-12-11T11:58:23Z
date_published: 1995-02-01T00:00:00Z
date_updated: 2022-06-29T08:18:48Z
day: '01'
extern: '1'
external_id:
  pmid:
  - '7757814 '
intvolume: '       318'
issue: '2'
language:
- iso: eng
main_file_link:
- url: https://pubmed.ncbi.nlm.nih.gov/7757814/
month: '02'
oa_version: None
page: 209 - 217
pmid: 1
publication: Comptes Rendus de l'Academie des Sciences - Series III
publication_identifier:
  issn:
  - 0764-4469
publication_status: published
publisher: Gauthier Villars Editeur
publist_id: '4340'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Localization of substance P receptors in central neural structures controlling
  daily rhythms in nocturnal rodents
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 318
year: '1995'
...