[{"abstract":[{"text":"We report the visible light photocatalytic cleavage of trityl thioethers or ethers under pH-neutral conditions. The method results in the formation of the respective symmetrical disulfides and alcohols in moderate to excellent yield. The protocol only requires the addition of a suitable photocatalyst and light rendering it orthogonal to several functionalities, including acid labile protective groups. The same conditions can be used to directly convert trityl-protected thiols into unsymmetrical disulfides or selenosulfides, and to cleave trityl resins in solid phase organic synthesis.","lang":"eng"}],"publication_status":"published","date_published":"2023-05-01T00:00:00Z","publisher":"Georg Thieme Verlag","volume":55,"quality_controlled":"1","page":"1367-1374","extern":"1","year":"2023","keyword":["Organic Chemistry","Catalysis"],"citation":{"apa":"Murakami, S., Brudy, C., Bachmann, M., Takemoto, Y., &#38; Pieber, B. (2023). Photocatalytic cleavage of trityl protected thiols and alcohols. <i>Synthesis</i>. Georg Thieme Verlag. <a href=\"https://doi.org/10.1055/a-1979-5933\">https://doi.org/10.1055/a-1979-5933</a>","short":"S. Murakami, C. Brudy, M. Bachmann, Y. Takemoto, B. Pieber, Synthesis 55 (2023) 1367–1374.","ieee":"S. Murakami, C. Brudy, M. Bachmann, Y. Takemoto, and B. Pieber, “Photocatalytic cleavage of trityl protected thiols and alcohols,” <i>Synthesis</i>, vol. 55, no. 09. Georg Thieme Verlag, pp. 1367–1374, 2023.","ama":"Murakami S, Brudy C, Bachmann M, Takemoto Y, Pieber B. Photocatalytic cleavage of trityl protected thiols and alcohols. <i>Synthesis</i>. 2023;55(09):1367-1374. doi:<a href=\"https://doi.org/10.1055/a-1979-5933\">10.1055/a-1979-5933</a>","mla":"Murakami, Sho, et al. “Photocatalytic Cleavage of Trityl Protected Thiols and Alcohols.” <i>Synthesis</i>, vol. 55, no. 09, Georg Thieme Verlag, 2023, pp. 1367–74, doi:<a href=\"https://doi.org/10.1055/a-1979-5933\">10.1055/a-1979-5933</a>.","ista":"Murakami S, Brudy C, Bachmann M, Takemoto Y, Pieber B. 2023. Photocatalytic cleavage of trityl protected thiols and alcohols. Synthesis. 55(09), 1367–1374.","chicago":"Murakami, Sho, Cosima Brudy, Moritz Bachmann, Yoshiji Takemoto, and Bartholomäus Pieber. “Photocatalytic Cleavage of Trityl Protected Thiols and Alcohols.” <i>Synthesis</i>. Georg Thieme Verlag, 2023. <a href=\"https://doi.org/10.1055/a-1979-5933\">https://doi.org/10.1055/a-1979-5933</a>."},"date_created":"2023-05-08T08:25:08Z","doi":"10.1055/a-1979-5933","_id":"12919","article_type":"original","publication_identifier":{"eissn":["1437-210X"],"issn":["0039-7881"]},"month":"05","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","oa_version":"None","author":[{"last_name":"Murakami","first_name":"Sho","full_name":"Murakami, Sho"},{"first_name":"Cosima","full_name":"Brudy, Cosima","last_name":"Brudy"},{"last_name":"Bachmann","first_name":"Moritz","full_name":"Bachmann, Moritz"},{"last_name":"Takemoto","full_name":"Takemoto, Yoshiji","first_name":"Yoshiji"},{"first_name":"Bartholomäus","full_name":"Pieber, Bartholomäus","orcid":"0000-0001-8689-388X","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","last_name":"Pieber"}],"status":"public","type":"journal_article","intvolume":"        55","scopus_import":"1","article_processing_charge":"No","issue":"09","date_updated":"2023-05-15T08:43:50Z","title":"Photocatalytic cleavage of trityl protected thiols and alcohols","publication":"Synthesis","language":[{"iso":"eng"}]}]