---
_id: '2252'
abstract:
- lang: eng
  text: The pattern of inheritance and mechanism of sex determination can have important
    evolutionary consequences. We studied probabilistic sex determination in the ciliate
    Tetrahymena thermophila, which was previously shown to cause evolution of skewed
    sex ratios. We find that the genetic background alters the sex determination patterns
    of mat alleles in heterozygotes and that allelic interaction can differentially
    influence the expression probability of the 7 sexes. We quantify the dominance
    relationships between several mat alleles and find that A-type alleles, which
    specify sex I, are indeed recessive to B-type alleles, which are unable to specify
    that sex. Our results provide additional support for the presence of modifier
    loci and raise implications for the dynamics of sex ratios in populations of T.
    thermophila.
article_processing_charge: No
author:
- first_name: Sujal
  full_name: Phadke, Sujal
  last_name: Phadke
- first_name: Tiago
  full_name: Paixao, Tiago
  id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
  last_name: Paixao
  orcid: 0000-0003-2361-3953
- first_name: Tuan
  full_name: Pham, Tuan
  last_name: Pham
- first_name: Stephanie
  full_name: Pham, Stephanie
  last_name: Pham
- first_name: Rebecca
  full_name: Zufall, Rebecca
  last_name: Zufall
citation:
  ama: Phadke S, Paixao T, Pham T, Pham S, Zufall R. Genetic background alters dominance
    relationships between mat alleles in the ciliate Tetrahymena Thermophila. <i>Journal
    of Heredity</i>. 2014;105(1):130-135. doi:<a href="https://doi.org/10.1093/jhered/est063">10.1093/jhered/est063</a>
  apa: Phadke, S., Paixao, T., Pham, T., Pham, S., &#38; Zufall, R. (2014). Genetic
    background alters dominance relationships between mat alleles in the ciliate Tetrahymena
    Thermophila. <i>Journal of Heredity</i>. Oxford University Press. <a href="https://doi.org/10.1093/jhered/est063">https://doi.org/10.1093/jhered/est063</a>
  chicago: Phadke, Sujal, Tiago Paixao, Tuan Pham, Stephanie Pham, and Rebecca Zufall.
    “Genetic Background Alters Dominance Relationships between Mat Alleles in the
    Ciliate Tetrahymena Thermophila.” <i>Journal of Heredity</i>. Oxford University
    Press, 2014. <a href="https://doi.org/10.1093/jhered/est063">https://doi.org/10.1093/jhered/est063</a>.
  ieee: S. Phadke, T. Paixao, T. Pham, S. Pham, and R. Zufall, “Genetic background
    alters dominance relationships between mat alleles in the ciliate Tetrahymena
    Thermophila,” <i>Journal of Heredity</i>, vol. 105, no. 1. Oxford University Press,
    pp. 130–135, 2014.
  ista: Phadke S, Paixao T, Pham T, Pham S, Zufall R. 2014. Genetic background alters
    dominance relationships between mat alleles in the ciliate Tetrahymena Thermophila.
    Journal of Heredity. 105(1), 130–135.
  mla: Phadke, Sujal, et al. “Genetic Background Alters Dominance Relationships between
    Mat Alleles in the Ciliate Tetrahymena Thermophila.” <i>Journal of Heredity</i>,
    vol. 105, no. 1, Oxford University Press, 2014, pp. 130–35, doi:<a href="https://doi.org/10.1093/jhered/est063">10.1093/jhered/est063</a>.
  short: S. Phadke, T. Paixao, T. Pham, S. Pham, R. Zufall, Journal of Heredity 105
    (2014) 130–135.
date_created: 2018-12-11T11:56:35Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2022-08-25T14:45:42Z
day: '01'
department:
- _id: NiBa
doi: 10.1093/jhered/est063
intvolume: '       105'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 130 - 135
publication: Journal of Heredity
publication_identifier:
  issn:
  - '00221503'
publication_status: published
publisher: Oxford University Press
publist_id: '4695'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Genetic background alters dominance relationships between mat alleles in the
  ciliate Tetrahymena Thermophila
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 105
year: '2014'
...