---
_id: '2567'
abstract:
- lang: eng
  text: Trigeminothalamic and spinothalamic-tact neurons provided with substance P
    receptor (SPR) were examined in the rat by SPR immunofluorescence histochemistry
    combined with Fluoro-Gold (FG) fluorescent retrograde labeling. After FG injection
    in the thalamic regions, FG-labeled cells with SPR-like immunoreactivity were
    seen mainly in laminae I and m of the medullary and spinal dorsal horns and lateral
    spinal nucleus. In these regions, about one-fourth to one-third of FG-labeled
    cells showed SPR-like immunoreactivity.
acknowledgement: "The authors are grateful for support of Dr. Kajitaro Morita in the
  Morita Clinic of Internal Medicine and Pediatrics at Kadoma, Osaka, and for photographic
  help of Mr. Akira Uesugi. This work was supported in part by Grants-in-Aid from
  the Ministry of Education, Science and Culture of Japan. \r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Jin
  full_name: Li, Jin
  last_name: Li
- first_name: Yu
  full_name: Ding, Yu
  last_name: Ding
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Noboru
  full_name: Mizuno, Noboru
  last_name: Mizuno
citation:
  ama: Li J, Ding Y, Shigemoto R, Mizuno N. Distribution of trigeminothalamic and
    spinothalamic-tract neurons showing substance P receptor-like immunoreactivity
    in the rat. <i>Brain Research</i>. 1996;719(1-2):207-212. doi:<a href="https://doi.org/10.1016/0006-8993(96)00064-9">10.1016/0006-8993(96)00064-9</a>
  apa: Li, J., Ding, Y., Shigemoto, R., &#38; Mizuno, N. (1996). Distribution of trigeminothalamic
    and spinothalamic-tract neurons showing substance P receptor-like immunoreactivity
    in the rat. <i>Brain Research</i>. Elsevier. <a href="https://doi.org/10.1016/0006-8993(96)00064-9">https://doi.org/10.1016/0006-8993(96)00064-9</a>
  chicago: Li, Jin, Yu Ding, Ryuichi Shigemoto, and Noboru Mizuno. “Distribution of
    Trigeminothalamic and Spinothalamic-Tract Neurons Showing Substance P Receptor-like
    Immunoreactivity in the Rat.” <i>Brain Research</i>. Elsevier, 1996. <a href="https://doi.org/10.1016/0006-8993(96)00064-9">https://doi.org/10.1016/0006-8993(96)00064-9</a>.
  ieee: J. Li, Y. Ding, R. Shigemoto, and N. Mizuno, “Distribution of trigeminothalamic
    and spinothalamic-tract neurons showing substance P receptor-like immunoreactivity
    in the rat,” <i>Brain Research</i>, vol. 719, no. 1–2. Elsevier, pp. 207–212,
    1996.
  ista: Li J, Ding Y, Shigemoto R, Mizuno N. 1996. Distribution of trigeminothalamic
    and spinothalamic-tract neurons showing substance P receptor-like immunoreactivity
    in the rat. Brain Research. 719(1–2), 207–212.
  mla: Li, Jin, et al. “Distribution of Trigeminothalamic and Spinothalamic-Tract
    Neurons Showing Substance P Receptor-like Immunoreactivity in the Rat.” <i>Brain
    Research</i>, vol. 719, no. 1–2, Elsevier, 1996, pp. 207–12, doi:<a href="https://doi.org/10.1016/0006-8993(96)00064-9">10.1016/0006-8993(96)00064-9</a>.
  short: J. Li, Y. Ding, R. Shigemoto, N. Mizuno, Brain Research 719 (1996) 207–212.
date_created: 2018-12-11T11:58:26Z
date_published: 1996-05-06T00:00:00Z
date_updated: 2022-08-12T08:25:35Z
day: '06'
doi: 10.1016/0006-8993(96)00064-9
extern: '1'
external_id:
  pmid:
  - '8782883 '
intvolume: '       719'
issue: 1-2
language:
- iso: eng
month: '05'
oa_version: None
page: 207 - 212
pmid: 1
publication: Brain Research
publication_identifier:
  issn:
  - 0006-8993
publication_status: published
publisher: Elsevier
publist_id: '4330'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distribution of trigeminothalamic and spinothalamic-tract neurons showing substance
  P receptor-like immunoreactivity in the rat
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 719
year: '1996'
...
---
_id: '2556'
abstract:
- lang: eng
  text: By using substance P receptor (SPR) immunofluorescence histochemistry combined
    with fluorescent retrograde labeling, SPR-like immunoreactive (SPR-LI) neurons
    sending their axons to the lateral parabrachial region were observed in the lumbar
    spinal cord of the rat. After injection of Fluoro-Gold into the lateral parabrachial
    region, retrogradely labeled neurons with SPR-LI were seen frequently in lamina
    I and the lateral spinal nucleus, and occasionally in laminae IV and V, with a
    predominantly contralateral distribution. Some of these neurons, especially those
    in lamina I, may convey nociceptive information to the lateral parabrachial region.
acknowledgement: The authors are grateful for photographic help of Mr. Akira Uesugi.
  This work was supported in part by Grants-in-Aid for Special Research on Priority
  Areas 05267104, Scientific Research (B) 05454658, and Scientific Research (C) 06680735
  from the Ministry of Education, Science and Culture of Japan.
article_processing_charge: No
article_type: original
author:
- first_name: Yu
  full_name: Ding, Yu
  last_name: Ding
- first_name: Masahiko
  full_name: Takada, Masahiko
  last_name: Takada
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Noboru
  full_name: Mizuno, Noboru
  last_name: Mizuno
citation:
  ama: Ding Y, Takada M, Shigemoto R, Mizuno N. Spinoparabrachial tract neurons showing
    substance P receptor-like immunoreactivity in the lumbar spinal cord of the rat.
    <i>Brain Research</i>. 1995;674(2):336-340. doi:<a href="https://doi.org/10.1016/0006-8993(95)00022-I">10.1016/0006-8993(95)00022-I</a>
  apa: Ding, Y., Takada, M., Shigemoto, R., &#38; Mizuno, N. (1995). Spinoparabrachial
    tract neurons showing substance P receptor-like immunoreactivity in the lumbar
    spinal cord of the rat. <i>Brain Research</i>. Elsevier. <a href="https://doi.org/10.1016/0006-8993(95)00022-I">https://doi.org/10.1016/0006-8993(95)00022-I</a>
  chicago: Ding, Yu, Masahiko Takada, Ryuichi Shigemoto, and Noboru Mizuno. “Spinoparabrachial
    Tract Neurons Showing Substance P Receptor-like Immunoreactivity in the Lumbar
    Spinal Cord of the Rat.” <i>Brain Research</i>. Elsevier, 1995. <a href="https://doi.org/10.1016/0006-8993(95)00022-I">https://doi.org/10.1016/0006-8993(95)00022-I</a>.
  ieee: Y. Ding, M. Takada, R. Shigemoto, and N. Mizuno, “Spinoparabrachial tract
    neurons showing substance P receptor-like immunoreactivity in the lumbar spinal
    cord of the rat,” <i>Brain Research</i>, vol. 674, no. 2. Elsevier, pp. 336–340,
    1995.
  ista: Ding Y, Takada M, Shigemoto R, Mizuno N. 1995. Spinoparabrachial tract neurons
    showing substance P receptor-like immunoreactivity in the lumbar spinal cord of
    the rat. Brain Research. 674(2), 336–340.
  mla: Ding, Yu, et al. “Spinoparabrachial Tract Neurons Showing Substance P Receptor-like
    Immunoreactivity in the Lumbar Spinal Cord of the Rat.” <i>Brain Research</i>,
    vol. 674, no. 2, Elsevier, 1995, pp. 336–40, doi:<a href="https://doi.org/10.1016/0006-8993(95)00022-I">10.1016/0006-8993(95)00022-I</a>.
  short: Y. Ding, M. Takada, R. Shigemoto, N. Mizuno, Brain Research 674 (1995) 336–340.
date_created: 2018-12-11T11:58:22Z
date_published: 1995-03-20T00:00:00Z
date_updated: 2022-06-29T08:32:01Z
day: '20'
doi: 10.1016/0006-8993(95)00022-I
extern: '1'
external_id:
  pmid:
  - '7796113'
intvolume: '       674'
issue: '2'
language:
- iso: eng
main_file_link:
- url: sciencedirect.com/science/article/pii/000689939500022I?via%3Dihub
month: '03'
oa_version: None
page: 336 - 340
pmid: 1
publication: Brain Research
publication_identifier:
  issn:
  - 0006-8993
publication_status: published
publisher: Elsevier
publist_id: '4341'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spinoparabrachial tract neurons showing substance P receptor-like immunoreactivity
  in the lumbar spinal cord of the rat
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 674
year: '1995'
...
---
_id: '2546'
abstract:
- lang: eng
  text: 'Immunochemical characteristics of neostriatal neurons producing substance
    P receptor (SPR) were examined in adult rats by double- and triple-immunofluorescence
    methods. In the neostriatum, SPR immunoreactivity was detected in large and medium-sized
    aspiny neurons. Virtually all SPR-immunoreactive neurons in the neostriatum contained
    somatostatin (SS) or choline acetyltransferase (ChAT), but not parvalbumin. All
    SS- and ChAT-immunoreactive neurons in the neostriatum showed SPR immunoreactivity.
    The co-existence of SS and ChAT was, however, not found in single neurons expressing
    SPR immunoreactivity. The present results indicate that neostriatal neurons immunoreactive
    for SPR are segregated into 2 groups: (1) medium-sized, aspiny somatostatinergic,
    and (2) large, aspiny cholinergic neurons.'
article_processing_charge: No
article_type: original
author:
- first_name: Takeshi
  full_name: Kaneko, Takeshi
  last_name: Kaneko
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Shigetada
  full_name: Nakanishi, Shigetada
  last_name: Nakanishi
- first_name: Noboru
  full_name: Mizuno, Noboru
  last_name: Mizuno
citation:
  ama: Kaneko T, Shigemoto R, Nakanishi S, Mizuno N. Substance P receptor-immunoreactive
    neurons in the rat neostriatum are segregated into somatostatinergic and cholinergic
    aspiny neurons. <i>Brain Research</i>. 1993;631(2):297-303. doi:<a href="https://doi.org/10.1016/0006-8993(93)91548-7">10.1016/0006-8993(93)91548-7</a>
  apa: Kaneko, T., Shigemoto, R., Nakanishi, S., &#38; Mizuno, N. (1993). Substance
    P receptor-immunoreactive neurons in the rat neostriatum are segregated into somatostatinergic
    and cholinergic aspiny neurons. <i>Brain Research</i>. Elsevier. <a href="https://doi.org/10.1016/0006-8993(93)91548-7">https://doi.org/10.1016/0006-8993(93)91548-7</a>
  chicago: Kaneko, Takeshi, Ryuichi Shigemoto, Shigetada Nakanishi, and Noboru Mizuno.
    “Substance P Receptor-Immunoreactive Neurons in the Rat Neostriatum Are Segregated
    into Somatostatinergic and Cholinergic Aspiny Neurons.” <i>Brain Research</i>.
    Elsevier, 1993. <a href="https://doi.org/10.1016/0006-8993(93)91548-7">https://doi.org/10.1016/0006-8993(93)91548-7</a>.
  ieee: T. Kaneko, R. Shigemoto, S. Nakanishi, and N. Mizuno, “Substance P receptor-immunoreactive
    neurons in the rat neostriatum are segregated into somatostatinergic and cholinergic
    aspiny neurons,” <i>Brain Research</i>, vol. 631, no. 2. Elsevier, pp. 297–303,
    1993.
  ista: Kaneko T, Shigemoto R, Nakanishi S, Mizuno N. 1993. Substance P receptor-immunoreactive
    neurons in the rat neostriatum are segregated into somatostatinergic and cholinergic
    aspiny neurons. Brain Research. 631(2), 297–303.
  mla: Kaneko, Takeshi, et al. “Substance P Receptor-Immunoreactive Neurons in the
    Rat Neostriatum Are Segregated into Somatostatinergic and Cholinergic Aspiny Neurons.”
    <i>Brain Research</i>, vol. 631, no. 2, Elsevier, 1993, pp. 297–303, doi:<a href="https://doi.org/10.1016/0006-8993(93)91548-7">10.1016/0006-8993(93)91548-7</a>.
  short: T. Kaneko, R. Shigemoto, S. Nakanishi, N. Mizuno, Brain Research 631 (1993)
    297–303.
date_created: 2018-12-11T11:58:18Z
date_published: 1993-12-24T00:00:00Z
date_updated: 2022-03-31T09:14:23Z
day: '24'
doi: 10.1016/0006-8993(93)91548-7
extern: '1'
external_id:
  pmid:
  - '7907524'
intvolume: '       631'
issue: '2'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/0006899393915487?via%3Dihub
month: '12'
oa_version: None
page: 297 - 303
pmid: 1
publication: Brain Research
publication_identifier:
  issn:
  - 0006-8993
publication_status: published
publisher: Elsevier
publist_id: '4353'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Substance P receptor-immunoreactive neurons in the rat neostriatum are segregated
  into somatostatinergic and cholinergic aspiny neurons
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 631
year: '1993'
...
---
_id: '2526'
abstract:
- lang: eng
  text: When WGA-HRP (wheat germ agglutinin-horseradish peroxidase conjugate) or HRP
    was injected into the regions around the superior central and/or the dorsal raphe
    nuclei in the cat, cell bodies of a number of non-pyramidal neurons were labeled
    in Ammon's horn. Thus the existence of direct projections from non-pyramidal neurons
    in Ammon's horn to the rostral raphe regions in the brainstem was suggested in
    the cat.
acknowledgement: The photographic help of Mr. Akira Uesugi, and the support of Niwa
  Medical Research Foundation are gratefully acknowledged. This work has been supported
  in part by Grant-in-Aid for Special Project Research (No. 63112003) and Grant-in-Aid
  for Scientific Research (No. 62480098) from the Ministry of Education, Science and
  Culture of Japan.
article_processing_charge: No
article_type: original
author:
- first_name: Tadashi
  full_name: Ino, Tadashi
  last_name: Ino
- first_name: Kazuo
  full_name: Itoh, Kazuo
  last_name: Itoh
- first_name: Hiroto
  full_name: Kamiya, Hiroto
  last_name: Kamiya
- first_name: Takeshi
  full_name: Kaneko, Takeshi
  last_name: Kaneko
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Ichiro
  full_name: Akiguchi, Ichiro
  last_name: Akiguchi
- first_name: Noboru
  full_name: Mizuno, Noboru
  last_name: Mizuno
citation:
  ama: Ino T, Itoh K, Kamiya H, et al. Direct projections from Ammon’s horn to the
    rostral raphe regions in the brainstem of the cat. <i>Brain Research</i>. 1989;479(1):157-161.
    doi:<a href="https://doi.org/10.1016/0006-8993(89)91346-2">10.1016/0006-8993(89)91346-2</a>
  apa: Ino, T., Itoh, K., Kamiya, H., Kaneko, T., Shigemoto, R., Akiguchi, I., &#38;
    Mizuno, N. (1989). Direct projections from Ammon’s horn to the rostral raphe regions
    in the brainstem of the cat. <i>Brain Research</i>. Elsevier. <a href="https://doi.org/10.1016/0006-8993(89)91346-2">https://doi.org/10.1016/0006-8993(89)91346-2</a>
  chicago: Ino, Tadashi, Kazuo Itoh, Hiroto Kamiya, Takeshi Kaneko, Ryuichi Shigemoto,
    Ichiro Akiguchi, and Noboru Mizuno. “Direct Projections from Ammon’s Horn to the
    Rostral Raphe Regions in the Brainstem of the Cat.” <i>Brain Research</i>. Elsevier,
    1989. <a href="https://doi.org/10.1016/0006-8993(89)91346-2">https://doi.org/10.1016/0006-8993(89)91346-2</a>.
  ieee: T. Ino <i>et al.</i>, “Direct projections from Ammon’s horn to the rostral
    raphe regions in the brainstem of the cat,” <i>Brain Research</i>, vol. 479, no.
    1. Elsevier, pp. 157–161, 1989.
  ista: Ino T, Itoh K, Kamiya H, Kaneko T, Shigemoto R, Akiguchi I, Mizuno N. 1989.
    Direct projections from Ammon’s horn to the rostral raphe regions in the brainstem
    of the cat. Brain Research. 479(1), 157–161.
  mla: Ino, Tadashi, et al. “Direct Projections from Ammon’s Horn to the Rostral Raphe
    Regions in the Brainstem of the Cat.” <i>Brain Research</i>, vol. 479, no. 1,
    Elsevier, 1989, pp. 157–61, doi:<a href="https://doi.org/10.1016/0006-8993(89)91346-2">10.1016/0006-8993(89)91346-2</a>.
  short: T. Ino, K. Itoh, H. Kamiya, T. Kaneko, R. Shigemoto, I. Akiguchi, N. Mizuno,
    Brain Research 479 (1989) 157–161.
date_created: 2018-12-11T11:58:11Z
date_published: 1989-02-06T00:00:00Z
date_updated: 2022-02-15T09:14:43Z
day: '06'
doi: 10.1016/0006-8993(89)91346-2
extern: '1'
external_id:
  pmid:
  - '2466535 '
intvolume: '       479'
issue: '1'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/0006899389913462?via%3Dihub
month: '02'
oa_version: None
page: 157 - 161
pmid: 1
publication: Brain Research
publication_identifier:
  eissn:
  - 1872-6240
  issn:
  - 0006-8993
publication_status: published
publisher: Elsevier
publist_id: '4373'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Direct projections from Ammon's horn to the rostral raphe regions in the brainstem
  of the cat
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 479
year: '1989'
...
---
_id: '2522'
abstract:
- lang: eng
  text: 'Non-pyramidal neurons in cat Ammon''s horn were shown to send their axons
    to the supramammillary regions (SMR), i.e. the supramammillary nucleus and its
    vicinities including the supramammillary nucleus and the lateral, posterior and
    dorsal hypothalamic areas: wheat germ agglutinin-horseradish peroxidase (WGA-HRP)
    injection into Ammon''s horn resulted in labeling of presumed axon terminals in
    the SMR; and after injecting HRP into the SMR, retrogradely labeled non-pyramidal
    neurons were seen in Ammon''s horn.'
acknowledgement: "The photographic help of Mr. Akira Uesugi and Mr. Kenichi Uesugi,
  and the support of the Niwa Medical Research \r\nFoundation are gratefully acknowledged.
  This work has also been supported in part by Grant-in-Aid for Scientific Research
  No. 62480098 from the Ministry of Education, Science and Culture of Japan."
article_processing_charge: No
article_type: original
author:
- first_name: Tadashi
  full_name: Ino, Tadashi
  last_name: Ino
- first_name: Kazuo
  full_name: Itoh, Kazuo
  last_name: Itoh
- first_name: Hiroto
  full_name: Kamiya, Hiroto
  last_name: Kamiya
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Ichiro
  full_name: Akiguchi, Ichiro
  last_name: Akiguchi
- first_name: Noboru
  full_name: Mizuno, Noboru
  last_name: Mizuno
citation:
  ama: Ino T, Itoh K, Kamiya H, Shigemoto R, Akiguchi I, Mizuno N. Direct projections
    of non-pyramidal neurons of Ammon’s horn to the supramammillary region in the
    cat. <i>Brain Research</i>. 1988;460(1):173-177. doi:<a href="https://doi.org/10.1016/0006-8993(88)91219-X">10.1016/0006-8993(88)91219-X</a>
  apa: Ino, T., Itoh, K., Kamiya, H., Shigemoto, R., Akiguchi, I., &#38; Mizuno, N.
    (1988). Direct projections of non-pyramidal neurons of Ammon’s horn to the supramammillary
    region in the cat. <i>Brain Research</i>. Elsevier. <a href="https://doi.org/10.1016/0006-8993(88)91219-X">https://doi.org/10.1016/0006-8993(88)91219-X</a>
  chicago: Ino, Tadashi, Kazuo Itoh, Hiroto Kamiya, Ryuichi Shigemoto, Ichiro Akiguchi,
    and Noboru Mizuno. “Direct Projections of Non-Pyramidal Neurons of Ammon’s Horn
    to the Supramammillary Region in the Cat.” <i>Brain Research</i>. Elsevier, 1988.
    <a href="https://doi.org/10.1016/0006-8993(88)91219-X">https://doi.org/10.1016/0006-8993(88)91219-X</a>.
  ieee: T. Ino, K. Itoh, H. Kamiya, R. Shigemoto, I. Akiguchi, and N. Mizuno, “Direct
    projections of non-pyramidal neurons of Ammon’s horn to the supramammillary region
    in the cat,” <i>Brain Research</i>, vol. 460, no. 1. Elsevier, pp. 173–177, 1988.
  ista: Ino T, Itoh K, Kamiya H, Shigemoto R, Akiguchi I, Mizuno N. 1988. Direct projections
    of non-pyramidal neurons of Ammon’s horn to the supramammillary region in the
    cat. Brain Research. 460(1), 173–177.
  mla: Ino, Tadashi, et al. “Direct Projections of Non-Pyramidal Neurons of Ammon’s
    Horn to the Supramammillary Region in the Cat.” <i>Brain Research</i>, vol. 460,
    no. 1, Elsevier, 1988, pp. 173–77, doi:<a href="https://doi.org/10.1016/0006-8993(88)91219-X">10.1016/0006-8993(88)91219-X</a>.
  short: T. Ino, K. Itoh, H. Kamiya, R. Shigemoto, I. Akiguchi, N. Mizuno, Brain Research
    460 (1988) 173–177.
date_created: 2018-12-11T11:58:10Z
date_published: 1988-09-13T00:00:00Z
date_updated: 2022-02-08T14:38:35Z
day: '13'
doi: 10.1016/0006-8993(88)91219-X
extern: '1'
external_id:
  pmid:
  - '2464404 '
intvolume: '       460'
issue: '1'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/000689938891219X?via%3Dihub
month: '09'
oa_version: None
page: 173 - 177
pmid: 1
publication: Brain Research
publication_identifier:
  eissn:
  - 1872-6240
  issn:
  - 0006-8993
publication_status: published
publisher: Elsevier
publist_id: '4376'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Direct projections of non-pyramidal neurons of Ammon's horn to the supramammillary
  region in the cat
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 460
year: '1988'
...
---
_id: '2524'
abstract:
- lang: eng
  text: Alpha-ketoglutamate (α-KG) reductive amination activity in rat brain was found
    to be mostly absorbed with an antibody against liver glutamate dehydrogenase.
    With this and anti-glutamine synthetase antibodies, α-KG reductive amination activity
    was immunocytochemically shown to coexist with glutamine synthetase activity in
    astrocytes. The results suggest that astrocytes de novo synthesize glutamate from
    α-KG and ammonia, and metabolize it to glutamine.
acknowledgement: 'The authors are grateful to Akira Uesugi and Ken’ichi Uesugi for
  photographic help. This work was supported by the Niwa Medical Research Foundation
  and Grants-in-Aid for Special -Project Research (62121004), for General Scientific
  Research (62480098) and for Encouragement of Young Scientists (63770043) from the
  Ministry of Education, Science and Culture of Japan. '
article_processing_charge: No
article_type: original
author:
- first_name: Takeshi
  full_name: Kaneko, Takeshi
  last_name: Kaneko
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Noboru
  full_name: Mizuno, Noboru
  last_name: Mizuno
citation:
  ama: Kaneko T, Shigemoto R, Mizuno N. Metabolism of glutamate and ammonia in astrocyte
    an immunocytochemical study. <i>Brain Research</i>. 1988;457(1):160-164. doi:<a
    href="https://doi.org/10.1016/0006-8993(88)90069-8">10.1016/0006-8993(88)90069-8</a>
  apa: Kaneko, T., Shigemoto, R., &#38; Mizuno, N. (1988). Metabolism of glutamate
    and ammonia in astrocyte an immunocytochemical study. <i>Brain Research</i>. Elsevier.
    <a href="https://doi.org/10.1016/0006-8993(88)90069-8">https://doi.org/10.1016/0006-8993(88)90069-8</a>
  chicago: Kaneko, Takeshi, Ryuichi Shigemoto, and Noboru Mizuno. “Metabolism of Glutamate
    and Ammonia in Astrocyte an Immunocytochemical Study.” <i>Brain Research</i>.
    Elsevier, 1988. <a href="https://doi.org/10.1016/0006-8993(88)90069-8">https://doi.org/10.1016/0006-8993(88)90069-8</a>.
  ieee: T. Kaneko, R. Shigemoto, and N. Mizuno, “Metabolism of glutamate and ammonia
    in astrocyte an immunocytochemical study,” <i>Brain Research</i>, vol. 457, no.
    1. Elsevier, pp. 160–164, 1988.
  ista: Kaneko T, Shigemoto R, Mizuno N. 1988. Metabolism of glutamate and ammonia
    in astrocyte an immunocytochemical study. Brain Research. 457(1), 160–164.
  mla: Kaneko, Takeshi, et al. “Metabolism of Glutamate and Ammonia in Astrocyte an
    Immunocytochemical Study.” <i>Brain Research</i>, vol. 457, no. 1, Elsevier, 1988,
    pp. 160–64, doi:<a href="https://doi.org/10.1016/0006-8993(88)90069-8">10.1016/0006-8993(88)90069-8</a>.
  short: T. Kaneko, R. Shigemoto, N. Mizuno, Brain Research 457 (1988) 160–164.
date_created: 2018-12-11T11:58:11Z
date_published: 1988-08-02T00:00:00Z
date_updated: 2022-02-08T13:52:37Z
day: '02'
doi: 10.1016/0006-8993(88)90069-8
extern: '1'
external_id:
  pmid:
  - '3167561'
intvolume: '       457'
issue: '1'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/0006899388900698?via%3Dihub
month: '08'
oa_version: None
page: 160 - 164
pmid: 1
publication: Brain Research
publication_identifier:
  eissn:
  - 1872-6240
  issn:
  - 0006-8993
publication_status: published
publisher: Elsevier
publist_id: '4375'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Metabolism of glutamate and ammonia in astrocyte an immunocytochemical study
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 457
year: '1988'
...
