@article{2567, abstract = {Trigeminothalamic and spinothalamic-tact neurons provided with substance P receptor (SPR) were examined in the rat by SPR immunofluorescence histochemistry combined with Fluoro-Gold (FG) fluorescent retrograde labeling. After FG injection in the thalamic regions, FG-labeled cells with SPR-like immunoreactivity were seen mainly in laminae I and m of the medullary and spinal dorsal horns and lateral spinal nucleus. In these regions, about one-fourth to one-third of FG-labeled cells showed SPR-like immunoreactivity.}, author = {Li, Jin and Ding, Yu and Shigemoto, Ryuichi and Mizuno, Noboru}, issn = {0006-8993}, journal = {Brain Research}, number = {1-2}, pages = {207 -- 212}, publisher = {Elsevier}, title = {{Distribution of trigeminothalamic and spinothalamic-tract neurons showing substance P receptor-like immunoreactivity in the rat}}, doi = {10.1016/0006-8993(96)00064-9}, volume = {719}, year = {1996}, } @article{2556, abstract = {By using substance P receptor (SPR) immunofluorescence histochemistry combined with fluorescent retrograde labeling, SPR-like immunoreactive (SPR-LI) neurons sending their axons to the lateral parabrachial region were observed in the lumbar spinal cord of the rat. After injection of Fluoro-Gold into the lateral parabrachial region, retrogradely labeled neurons with SPR-LI were seen frequently in lamina I and the lateral spinal nucleus, and occasionally in laminae IV and V, with a predominantly contralateral distribution. Some of these neurons, especially those in lamina I, may convey nociceptive information to the lateral parabrachial region.}, author = {Ding, Yu and Takada, Masahiko and Shigemoto, Ryuichi and Mizuno, Noboru}, issn = {0006-8993}, journal = {Brain Research}, number = {2}, pages = {336 -- 340}, publisher = {Elsevier}, title = {{Spinoparabrachial tract neurons showing substance P receptor-like immunoreactivity in the lumbar spinal cord of the rat}}, doi = {10.1016/0006-8993(95)00022-I}, volume = {674}, year = {1995}, } @article{2546, abstract = {Immunochemical characteristics of neostriatal neurons producing substance P receptor (SPR) were examined in adult rats by double- and triple-immunofluorescence methods. In the neostriatum, SPR immunoreactivity was detected in large and medium-sized aspiny neurons. Virtually all SPR-immunoreactive neurons in the neostriatum contained somatostatin (SS) or choline acetyltransferase (ChAT), but not parvalbumin. All SS- and ChAT-immunoreactive neurons in the neostriatum showed SPR immunoreactivity. The co-existence of SS and ChAT was, however, not found in single neurons expressing SPR immunoreactivity. The present results indicate that neostriatal neurons immunoreactive for SPR are segregated into 2 groups: (1) medium-sized, aspiny somatostatinergic, and (2) large, aspiny cholinergic neurons.}, author = {Kaneko, Takeshi and Shigemoto, Ryuichi and Nakanishi, Shigetada and Mizuno, Noboru}, issn = {0006-8993}, journal = {Brain Research}, number = {2}, pages = {297 -- 303}, publisher = {Elsevier}, title = {{Substance P receptor-immunoreactive neurons in the rat neostriatum are segregated into somatostatinergic and cholinergic aspiny neurons}}, doi = {10.1016/0006-8993(93)91548-7}, volume = {631}, year = {1993}, } @article{2526, abstract = {When WGA-HRP (wheat germ agglutinin-horseradish peroxidase conjugate) or HRP was injected into the regions around the superior central and/or the dorsal raphe nuclei in the cat, cell bodies of a number of non-pyramidal neurons were labeled in Ammon's horn. Thus the existence of direct projections from non-pyramidal neurons in Ammon's horn to the rostral raphe regions in the brainstem was suggested in the cat.}, author = {Ino, Tadashi and Itoh, Kazuo and Kamiya, Hiroto and Kaneko, Takeshi and Shigemoto, Ryuichi and Akiguchi, Ichiro and Mizuno, Noboru}, issn = {1872-6240}, journal = {Brain Research}, number = {1}, pages = {157 -- 161}, publisher = {Elsevier}, title = {{Direct projections from Ammon's horn to the rostral raphe regions in the brainstem of the cat}}, doi = {10.1016/0006-8993(89)91346-2}, volume = {479}, year = {1989}, } @article{2522, abstract = {Non-pyramidal neurons in cat Ammon's horn were shown to send their axons to the supramammillary regions (SMR), i.e. the supramammillary nucleus and its vicinities including the supramammillary nucleus and the lateral, posterior and dorsal hypothalamic areas: wheat germ agglutinin-horseradish peroxidase (WGA-HRP) injection into Ammon's horn resulted in labeling of presumed axon terminals in the SMR; and after injecting HRP into the SMR, retrogradely labeled non-pyramidal neurons were seen in Ammon's horn.}, author = {Ino, Tadashi and Itoh, Kazuo and Kamiya, Hiroto and Shigemoto, Ryuichi and Akiguchi, Ichiro and Mizuno, Noboru}, issn = {1872-6240}, journal = {Brain Research}, number = {1}, pages = {173 -- 177}, publisher = {Elsevier}, title = {{Direct projections of non-pyramidal neurons of Ammon's horn to the supramammillary region in the cat}}, doi = {10.1016/0006-8993(88)91219-X}, volume = {460}, year = {1988}, } @article{2524, abstract = {Alpha-ketoglutamate (α-KG) reductive amination activity in rat brain was found to be mostly absorbed with an antibody against liver glutamate dehydrogenase. With this and anti-glutamine synthetase antibodies, α-KG reductive amination activity was immunocytochemically shown to coexist with glutamine synthetase activity in astrocytes. The results suggest that astrocytes de novo synthesize glutamate from α-KG and ammonia, and metabolize it to glutamine.}, author = {Kaneko, Takeshi and Shigemoto, Ryuichi and Mizuno, Noboru}, issn = {1872-6240}, journal = {Brain Research}, number = {1}, pages = {160 -- 164}, publisher = {Elsevier}, title = {{Metabolism of glutamate and ammonia in astrocyte an immunocytochemical study}}, doi = {10.1016/0006-8993(88)90069-8}, volume = {457}, year = {1988}, }