---
_id: '2538'
abstract:
- lang: eng
  text: Rat mRNAs encoding two subtypes of the endothelin (ET) receptor (ET(A) and
    ET(B)) were studied in the rat ovary and fallopian tube by means of Northern blotting
    and in situ hybridization. The mRNA transcripts for the endothelin- 1-specific
    type receptor (ET(A)) in pooled RNA from the ovary and fallopian tube were 4.2
    and 5.2 kilonucleotides, and that for the nonselective type receptor (ET(B)) was
    4.7 kilonucleotides; these were similar to transcripts for endothelin receptors
    from other tissues. ET(A) mRNA expression was abundant in the muscle cell layer
    of the fallopian tube, but low in the ovary. On the other hand, ET(B) mRNA was
    abundant in the granulosa cells in the developing follicles, but low in atretic
    follicles and absent in the fallopian tube. These results demonstrated that the
    mRNAs for the two subtypes of the rat endothelin receptor have different expression
    profiles in the ovary and fallopian tube. ETs may mainly affect the granulosa
    cells in the dominant follicles as well as the muscle cells of the fallopian tube
    through ET(B) and ET(A), respectively.
acknowledgement: We thank Ms. Fumiko Kosaka for her excellent technical assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Masazumi
  full_name: Iwai, Masazumi
  last_name: Iwai
- first_name: Seiji
  full_name: Hori, Seiji
  last_name: Hori
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Hideharu
  full_name: Kanzaki, Hideharu
  last_name: Kanzaki
- first_name: Takahide
  full_name: Mori, Takahide
  last_name: Mori
- first_name: Shigetada
  full_name: Nakanishi, Shigetada
  last_name: Nakanishi
citation:
  ama: Iwai M, Hori S, Shigemoto R, Kanzaki H, Mori T, Nakanishi S. Localization of
    endothelin receptor messenger ribonucleic acid in the rat ovary and fallopian
    tube by in situ hybridization. <i>Biology of Reproduction</i>. 1993;49(4):675-680.
    doi:<a href="https://doi.org/10.1095/biolreprod49.4.675">10.1095/biolreprod49.4.675</a>
  apa: Iwai, M., Hori, S., Shigemoto, R., Kanzaki, H., Mori, T., &#38; Nakanishi,
    S. (1993). Localization of endothelin receptor messenger ribonucleic acid in the
    rat ovary and fallopian tube by in situ hybridization. <i>Biology of Reproduction</i>.
    Society for the Study of Reproduction. <a href="https://doi.org/10.1095/biolreprod49.4.675">https://doi.org/10.1095/biolreprod49.4.675</a>
  chicago: Iwai, Masazumi, Seiji Hori, Ryuichi Shigemoto, Hideharu Kanzaki, Takahide
    Mori, and Shigetada Nakanishi. “Localization of Endothelin Receptor Messenger
    Ribonucleic Acid in the Rat Ovary and Fallopian Tube by in Situ Hybridization.”
    <i>Biology of Reproduction</i>. Society for the Study of Reproduction, 1993. <a
    href="https://doi.org/10.1095/biolreprod49.4.675">https://doi.org/10.1095/biolreprod49.4.675</a>.
  ieee: M. Iwai, S. Hori, R. Shigemoto, H. Kanzaki, T. Mori, and S. Nakanishi, “Localization
    of endothelin receptor messenger ribonucleic acid in the rat ovary and fallopian
    tube by in situ hybridization,” <i>Biology of Reproduction</i>, vol. 49, no. 4.
    Society for the Study of Reproduction, pp. 675–680, 1993.
  ista: Iwai M, Hori S, Shigemoto R, Kanzaki H, Mori T, Nakanishi S. 1993. Localization
    of endothelin receptor messenger ribonucleic acid in the rat ovary and fallopian
    tube by in situ hybridization. Biology of Reproduction. 49(4), 675–680.
  mla: Iwai, Masazumi, et al. “Localization of Endothelin Receptor Messenger Ribonucleic
    Acid in the Rat Ovary and Fallopian Tube by in Situ Hybridization.” <i>Biology
    of Reproduction</i>, vol. 49, no. 4, Society for the Study of Reproduction, 1993,
    pp. 675–80, doi:<a href="https://doi.org/10.1095/biolreprod49.4.675">10.1095/biolreprod49.4.675</a>.
  short: M. Iwai, S. Hori, R. Shigemoto, H. Kanzaki, T. Mori, S. Nakanishi, Biology
    of Reproduction 49 (1993) 675–680.
date_created: 2018-12-11T11:58:16Z
date_published: 1993-10-01T00:00:00Z
date_updated: 2022-03-31T12:32:51Z
day: '01'
doi: 10.1095/biolreprod49.4.675
extern: '1'
external_id:
  pmid:
  - '8218631'
intvolume: '        49'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://academic.oup.com/biolreprod/article/49/4/675/2762375?login=true
month: '10'
oa: 1
oa_version: Published Version
page: 675 - 680
pmid: 1
publication: Biology of Reproduction
publication_identifier:
  issn:
  - 0006-3363
publication_status: published
publisher: Society for the Study of Reproduction
publist_id: '4359'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Localization of endothelin receptor messenger ribonucleic acid in the rat ovary
  and fallopian tube by in situ hybridization
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 49
year: '1993'
...