---
_id: '11989'
abstract:
- lang: eng
  text: In recent years, the high demand for sustainable processes resulted in the
    development of highly attractive oxidation protocols utilizing molecular oxygen
    or even air instead of more uneconomic and often toxic reagents. The application
    of these sustainable, gaseous oxidants in conventional batch reactors is often
    associated with severe safety risks and process challenges especially on larger
    scales. Continuous flow technology offers the possibility to minimize these safety
    hazards and concurrently allows working in high-temperature/high-pressure regimes
    to access highly efficient oxidation protocols. This review article critically
    discusses recent literature examples of flow methodologies for selective aerobic
    oxidations of organic compounds. Several technologies and reactor designs for
    biphasic gas/liquid as well as supercritical reaction media are presented in detail.
    © Springer International Publishing Switzerland 2015.
alternative_title:
- Topics in Organometallic Chemistry
article_processing_charge: No
author:
- first_name: Bartholomäus
  full_name: Pieber, Bartholomäus
  id: 93e5e5b2-0da6-11ed-8a41-af589a024726
  last_name: Pieber
  orcid: 0000-0001-8689-388X
- first_name: C. Oliver
  full_name: Kappe, C. Oliver
  last_name: Kappe
citation:
  ama: 'Pieber B, Kappe CO. Aerobic oxidations in continuous flow. In: Noël T, ed.
    <i>Organometallic Flow Chemistry</i>. Vol 57. 1st ed. TOPORGAN. Cham: Springer
    Nature; 2015:97–136. doi:<a href="https://doi.org/10.1007/3418_2015_133">10.1007/3418_2015_133</a>'
  apa: 'Pieber, B., &#38; Kappe, C. O. (2015). Aerobic oxidations in continuous flow.
    In T. Noël (Ed.), <i>Organometallic Flow Chemistry</i> (1st ed., Vol. 57, pp.
    97–136). Cham: Springer Nature. <a href="https://doi.org/10.1007/3418_2015_133">https://doi.org/10.1007/3418_2015_133</a>'
  chicago: 'Pieber, Bartholomäus, and C. Oliver Kappe. “Aerobic Oxidations in Continuous
    Flow.” In <i>Organometallic Flow Chemistry</i>, edited by Timothy Noël, 1st ed.,
    57:97–136. TOPORGAN. Cham: Springer Nature, 2015. <a href="https://doi.org/10.1007/3418_2015_133">https://doi.org/10.1007/3418_2015_133</a>.'
  ieee: 'B. Pieber and C. O. Kappe, “Aerobic oxidations in continuous flow,” in <i>Organometallic
    Flow Chemistry</i>, 1st ed., vol. 57, T. Noël, Ed. Cham: Springer Nature, 2015,
    pp. 97–136.'
  ista: 'Pieber B, Kappe CO. 2015.Aerobic oxidations in continuous flow. In: Organometallic
    Flow Chemistry. Topics in Organometallic Chemistry, vol. 57, 97–136.'
  mla: Pieber, Bartholomäus, and C. Oliver Kappe. “Aerobic Oxidations in Continuous
    Flow.” <i>Organometallic Flow Chemistry</i>, edited by Timothy Noël, 1st ed.,
    vol. 57, Springer Nature, 2015, pp. 97–136, doi:<a href="https://doi.org/10.1007/3418_2015_133">10.1007/3418_2015_133</a>.
  short: B. Pieber, C.O. Kappe, in:, T. Noël (Ed.), Organometallic Flow Chemistry,
    1st ed., Springer Nature, Cham, 2015, pp. 97–136.
date_created: 2022-08-25T11:58:38Z
date_published: 2015-06-10T00:00:00Z
date_updated: 2023-02-21T10:10:35Z
day: '10'
doi: 10.1007/3418_2015_133
edition: '1'
editor:
- first_name: Timothy
  full_name: Noël, Timothy
  last_name: Noël
extern: '1'
intvolume: '        57'
language:
- iso: eng
month: '06'
oa_version: None
page: 97–136
place: Cham
publication: Organometallic Flow Chemistry
publication_identifier:
  eisbn:
  - '9783319332437'
  eissn:
  - 1616-8534
  isbn:
  - '9783319332413'
  issn:
  - 1436-6002
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
series_title: TOPORGAN
status: public
title: Aerobic oxidations in continuous flow
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 57
year: '2015'
...