---
_id: '9123'
abstract:
- lang: eng
  text: 'Inversions are chromosomal rearrangements where the order of genes is reversed.
    Inversions originate by mutation and can be under positive, negative or balancing
    selection. Selective effects result from potential disruptive effects on meiosis,
    gene disruption at inversion breakpoints and, importantly, the effects of inversions
    as modifiers of recombination rate: Recombination is strongly reduced in individuals
    heterozygous for an inversion, allowing for alleles at different loci to be inherited
    as a ‘block’. This may lead to a selective advantage whenever it is favourable
    to keep certain combinations of alleles associated, for example under local adaptation
    with gene flow. Inversions can cover a considerable part of a chromosome and contain
    numerous loci under different selection pressures, so that the resulting overall
    effects may be complex. Empirical data from various systems show that inversions
    may have a prominent role in local adaptation, speciation, parallel evolution,
    the maintenance of polymorphism and sex chromosome evolution.'
article_processing_charge: No
author:
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
citation:
  ama: 'Westram AM, Faria R, Butlin R, Johannesson K. Inversions and Evolution. In:
    <i>ELS</i>. Wiley; 2020. doi:<a href="https://doi.org/10.1002/9780470015902.a0029007">10.1002/9780470015902.a0029007</a>'
  apa: Westram, A. M., Faria, R., Butlin, R., &#38; Johannesson, K. (2020). Inversions
    and Evolution. In <i>eLS</i>. Wiley. <a href="https://doi.org/10.1002/9780470015902.a0029007">https://doi.org/10.1002/9780470015902.a0029007</a>
  chicago: Westram, Anja M, Rui Faria, Roger Butlin, and Kerstin Johannesson. “Inversions
    and Evolution.” In <i>ELS</i>. Wiley, 2020. <a href="https://doi.org/10.1002/9780470015902.a0029007">https://doi.org/10.1002/9780470015902.a0029007</a>.
  ieee: A. M. Westram, R. Faria, R. Butlin, and K. Johannesson, “Inversions and Evolution,”
    in <i>eLS</i>, Wiley, 2020.
  ista: 'Westram AM, Faria R, Butlin R, Johannesson K. 2020.Inversions and Evolution.
    In: eLS. .'
  mla: Westram, Anja M., et al. “Inversions and Evolution.” <i>ELS</i>, Wiley, 2020,
    doi:<a href="https://doi.org/10.1002/9780470015902.a0029007">10.1002/9780470015902.a0029007</a>.
  short: A.M. Westram, R. Faria, R. Butlin, K. Johannesson, in:, ELS, Wiley, 2020.
date_created: 2021-02-15T12:39:04Z
date_published: 2020-05-16T00:00:00Z
date_updated: 2021-02-15T13:18:16Z
day: '16'
department:
- _id: NiBa
doi: 10.1002/9780470015902.a0029007
language:
- iso: eng
month: '05'
oa_version: None
publication: eLS
publication_identifier:
  isbn:
  - '9780470016176'
  - '9780470015902'
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Inversions and Evolution
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...