---
_id: '11879'
abstract:
- lang: eng
  text: "As the overall global mean surface temperature is increasing due to climate
    change, plant\r\nadaptation to those stressful conditions is of utmost importance
    for their survival. Plants are\r\nsessile organisms, thus to compensate for their
    lack of mobility, they evolved a variety of\r\nmechanisms enabling them to flexibly
    adjust their physiological, growth and developmental\r\nprocesses to fluctuating
    temperatures and to survive in harsh environments. While these unique\r\nadaptation
    abilities provide an important evolutionary advantage, overall modulation of plant\r\ngrowth
    and developmental program due to non-optimal temperature negatively affects biomass\r\nproduction,
    crop productivity or sensitivity to pathogens. Thus, understanding molecular\r\nprocesses
    underlying plant adaptation to increased temperature can provide important\r\nresources
    for breeding strategies to ensure sufficient agricultural food production.\r\nAn
    increase in ambient temperature by a few degrees leads to profound changes in
    organ growth\r\nincluding enhanced hypocotyl elongation, expansion of petioles,
    hyponastic growth of leaves and\r\ncotyledons, collectively named thermomorphogenesis
    (Casal & Balasubramanian, 2019). Auxin,\r\none of the best-studied growth hormones,
    plays an essential role in this process by direct\r\nactivation of transcriptional
    and non-transcriptional processes resulting in elongation growth\r\n(Majda & Robert,
    2018).To modulate hypocotyl growth in response to high ambient temperature\r\n(hAT),
    auxin needs to be redistributed accordingly. PINs, auxin efflux transporters,
    are key\r\ncomponents of the polar auxin transport (PAT) machinery, which controls
    the amount and\r\ndirection of auxin translocated in the plant tissues and organs(Adamowski
    & Friml, 2015). Hence,\r\nPIN-mediated transport is tightly linked with thermo-morphogenesis,
    and interference with PAT\r\nthrough either chemical or genetic means dramatically
    affecting the adaptive responses to hAT.\r\nIntriguingly, despite the key role
    of PIN mediated transport in growth response to hAT, whether\r\nand how PINs at
    the level of expression adapt to fluctuation in temperature is scarcely\r\nunderstood.\r\nWith
    genetic, molecular and advanced bio-imaging approaches, we demonstrate the role
    of PIN\r\nauxin transporters in the regulation of hypocotyl growth in response
    to hAT. We show that via\r\nadjustment of PIN3, PIN4 and PIN7 expression in cotyledons
    and hypocotyls, auxin distribution is modulated thereby determining elongation
    pattern of epidermal cells at hAT. Furthermore, we\r\nidentified three Zinc-Finger
    (ZF) transcription factors as novel molecular components of the\r\nthermo-regulatory
    network, which through negative regulation of PIN transcription adjust the\r\ntransport
    of auxin at hAT. Our results suggest that the ZF-PIN module might be a part of
    the\r\nnegative feedback loop attenuating the activity of the thermo-sensing pathway
    to restrain\r\nexaggerated growth and developmental responses to hAT."
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: SSU
acknowledgement: I would like to acknowledge ISTA and all the people from the Scientific
  Service Units and at ISTA, in particular Dorota Jaworska for excellent technical
  and scientific support as well as ÖAW for funding my research for over 3 years (DOC
  ÖAW Fellowship PR1022OEAW02).
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Christina
  full_name: Artner, Christina
  id: 45DF286A-F248-11E8-B48F-1D18A9856A87
  last_name: Artner
citation:
  ama: Artner C. Modulation of auxin transport via ZF proteins adjust plant response
    to high ambient temperature. 2022. doi:<a href="https://doi.org/10.15479/at:ista:11879">10.15479/at:ista:11879</a>
  apa: Artner, C. (2022). <i>Modulation of auxin transport via ZF proteins adjust
    plant response to high ambient temperature</i>. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/at:ista:11879">https://doi.org/10.15479/at:ista:11879</a>
  chicago: Artner, Christina. “Modulation of Auxin Transport via ZF Proteins Adjust
    Plant Response to High Ambient Temperature.” Institute of Science and Technology
    Austria, 2022. <a href="https://doi.org/10.15479/at:ista:11879">https://doi.org/10.15479/at:ista:11879</a>.
  ieee: C. Artner, “Modulation of auxin transport via ZF proteins adjust plant response
    to high ambient temperature,” Institute of Science and Technology Austria, 2022.
  ista: Artner C. 2022. Modulation of auxin transport via ZF proteins adjust plant
    response to high ambient temperature. Institute of Science and Technology Austria.
  mla: Artner, Christina. <i>Modulation of Auxin Transport via ZF Proteins Adjust
    Plant Response to High Ambient Temperature</i>. Institute of Science and Technology
    Austria, 2022, doi:<a href="https://doi.org/10.15479/at:ista:11879">10.15479/at:ista:11879</a>.
  short: C. Artner, Modulation of Auxin Transport via ZF Proteins Adjust Plant Response
    to High Ambient Temperature, Institute of Science and Technology Austria, 2022.
date_created: 2022-08-17T07:58:53Z
date_published: 2022-08-17T00:00:00Z
date_updated: 2023-09-09T22:30:04Z
day: '17'
ddc:
- '580'
degree_awarded: PhD
department:
- _id: GradSch
- _id: EvBe
doi: 10.15479/at:ista:11879
file:
- access_level: open_access
  checksum: a2c2fdc28002538840490bfa6a08b2cb
  content_type: application/pdf
  creator: cartner
  date_created: 2022-08-17T12:08:49Z
  date_updated: 2023-09-09T22:30:03Z
  embargo: 2023-09-08
  file_id: '11907'
  file_name: ChristinaArtner_PhD_Thesis_2022.pdf
  file_size: 11113608
  relation: main_file
- access_level: closed
  checksum: 66b461c074b815fbe63481b3f46a9f43
  content_type: application/octet-stream
  creator: cartner
  date_created: 2022-08-17T12:08:59Z
  date_updated: 2023-09-09T22:30:03Z
  embargo_to: open_access
  file_id: '11908'
  file_name: ChristinaArtner_PhD_Thesis_2022.7z
  file_size: 19097730
  relation: source_file
file_date_updated: 2023-09-09T22:30:03Z
has_accepted_license: '1'
keyword:
- high ambient temperature
- auxin
- PINs
- Zinc-Finger proteins
- thermomorphogenesis
- stress
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '128'
project:
- _id: 2685A872-B435-11E9-9278-68D0E5697425
  name: Hormonal regulation of plant adaptive responses to environmental signals
publication_identifier:
  isbn:
  - 978-3-99078-022-0
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
title: Modulation of auxin transport via ZF proteins adjust plant response to high
  ambient temperature
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...