---
_id: '11626'
abstract:
- lang: eng
  text: Plant growth and development is well known to be both, flexible and dynamic.
    The high capacity for post-embryonic organ formation and tissue regeneration requires
    tightly regulated intercellular communication and coordinated tissue polarization.
    One of the most important drivers for patterning and polarity in plant development
    is the phytohormone auxin. Auxin has the unique characteristic to establish polarized
    channels for its own active directional cell to cell transport. This fascinating
    phenomenon is called auxin canalization. Those auxin transport channels are characterized
    by the expression and polar, subcellular localization of PIN auxin efflux carriers.
    PIN proteins have the ability to dynamically change their localization and auxin
    itself can affect this by interfering with trafficking. Most of the underlying
    molecular mechanisms of canalization still remain enigmatic. What is known so
    far is that canonical auxin signaling is indispensable but also other non-canonical
    signaling components are thought to play a role. In order to shed light into the
    mysteries auf auxin canalization this study revisits the branches of auxin signaling
    in detail. Further a new auxin analogue, PISA, is developed which triggers auxin-like
    responses but does not directly activate canonical transcriptional auxin signaling.
    We revisit the direct auxin effect on PIN trafficking where we found that, contradictory
    to previous observations, auxin is very specifically promoting endocytosis of
    PIN2 but has no overall effect on endocytosis. Further, we evaluate which cellular
    processes related to PIN subcellular dynamics are involved in the establishment
    of auxin conducting channels and the formation of vascular tissue. We are re-evaluating
    the function of AUXIN BINDING PROTEIN 1 (ABP1) and provide a comprehensive picture
    about its developmental phneotypes and involvement in auxin signaling and canalization.
    Lastly, we are focusing on the crosstalk between the hormone strigolactone (SL)
    and auxin and found that SL is interfering with essentially all processes involved
    in auxin canalization in a non-transcriptional manner. Lastly we identify a new
    way of SL perception and signaling which is emanating from mitochondria, is independent
    of canonical SL signaling and is modulating primary root growth.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Michelle C
  full_name: Gallei, Michelle C
  id: 35A03822-F248-11E8-B48F-1D18A9856A87
  last_name: Gallei
  orcid: 0000-0003-1286-7368
citation:
  ama: Gallei MC. Auxin and strigolactone non-canonical signaling regulating development
    in Arabidopsis thaliana. 2022. doi:<a href="https://doi.org/10.15479/at:ista:11626">10.15479/at:ista:11626</a>
  apa: Gallei, M. C. (2022). <i>Auxin and strigolactone non-canonical signaling regulating
    development in Arabidopsis thaliana</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/at:ista:11626">https://doi.org/10.15479/at:ista:11626</a>
  chicago: Gallei, Michelle C. “Auxin and Strigolactone Non-Canonical Signaling Regulating
    Development in Arabidopsis Thaliana.” Institute of Science and Technology Austria,
    2022. <a href="https://doi.org/10.15479/at:ista:11626">https://doi.org/10.15479/at:ista:11626</a>.
  ieee: M. C. Gallei, “Auxin and strigolactone non-canonical signaling regulating
    development in Arabidopsis thaliana,” Institute of Science and Technology Austria,
    2022.
  ista: Gallei MC. 2022. Auxin and strigolactone non-canonical signaling regulating
    development in Arabidopsis thaliana. Institute of Science and Technology Austria.
  mla: Gallei, Michelle C. <i>Auxin and Strigolactone Non-Canonical Signaling Regulating
    Development in Arabidopsis Thaliana</i>. Institute of Science and Technology Austria,
    2022, doi:<a href="https://doi.org/10.15479/at:ista:11626">10.15479/at:ista:11626</a>.
  short: M.C. Gallei, Auxin and Strigolactone Non-Canonical Signaling Regulating Development
    in Arabidopsis Thaliana, Institute of Science and Technology Austria, 2022.
date_created: 2022-07-20T11:21:53Z
date_published: 2022-07-20T00:00:00Z
date_updated: 2024-10-29T10:22:45Z
day: '20'
ddc:
- '575'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JiFr
doi: 10.15479/at:ista:11626
ec_funded: 1
file:
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  date_updated: 2022-07-25T09:08:47Z
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  date_updated: 2022-07-25T09:39:58Z
  description: This is the print version of the thesis including the full appendix
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file_date_updated: 2022-07-25T11:48:45Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '248'
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication_identifier:
  isbn:
  - 978-3-99078-019-0
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '9287'
    relation: part_of_dissertation
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status: public
supervisor:
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Eilon
  full_name: Shani, Eilon
  last_name: Shani
title: Auxin and strigolactone non-canonical signaling regulating development in Arabidopsis
  thaliana
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2022'
...