---
_id: '3166'
abstract:
- lang: eng
text: 'There is evidence that the genetic code was established prior to the existence
of proteins, when metabolism was powered by ribozymes. Also, early proto-organisms
had to rely on simple anaerobic bioenergetic processes. In this work I propose
that amino acid fermentation powered metabolism in the RNA world, and that this
was facilitated by proto-adapters, the precursors of the tRNAs. Amino acids were
used as carbon sources rather than as catalytic or structural elements. In modern
bacteria, amino acid fermentation is known as the Stickland reaction. This pathway
involves two amino acids: the first undergoes oxidative deamination, and the second
acts as an electron acceptor through reductive deamination. This redox reaction
results in two keto acids that are employed to synthesise ATP via substrate-level
phosphorylation. The Stickland reaction is the basic bioenergetic pathway of some
bacteria of the genus Clostridium. Two other facts support Stickland fermentation
in the RNA world. First, several Stickland amino acid pairs are synthesised in
abiotic amino acid synthesis. This suggests that amino acids that could be used
as an energy substrate were freely available. Second, anticodons that have complementary
sequences often correspond to amino acids that form Stickland pairs. The main
hypothesis of this paper is that pairs of complementary proto-adapters were assigned
to Stickland amino acids pairs. There are signatures of this hypothesis in the
genetic code. Furthermore, it is argued that the proto-adapters formed double
strands that brought amino acid pairs into proximity to facilitate their mutual
redox reaction, structurally constraining the anticodon pairs that are assigned
to these amino acid pairs. Significance tests which randomise the code are performed
to study the extent of the variability of the energetic (ATP) yield. Random assignments
can lead to a substantial yield of ATP and maintain enough variability, thus selection
can act and refine the assignments into a proto-code that optimises the energetic
yield. Monte Carlo simulations are performed to evaluate the establishment of
these simple proto-codes, based on amino acid substitutions and codon swapping.
In all cases, donor amino acids are assigned to anticodons composed of U+G, and
have low redundancy (1-2 codons), whereas acceptor amino acids are assigned to
the the remaining codons. These bioenergetic and structural constraints allow
for a metabolic role for amino acids before their co-option as catalyst cofactors.
Reviewers: this article was reviewed by Prof. William Martin, Prof. Eors Szathmary
(nominated by Dr. Gaspar Jekely) and Dr. Adam Kun (nominated by Dr. Sandor Pongor)'
acknowledgement: 'The author was supported by the ERC-2009-AdG Grant for project 250152
SELECTIONINFORMATION. '
article_number: '6'
author:
- first_name: Harold
full_name: Vladar, Harold
id: 2A181218-F248-11E8-B48F-1D18A9856A87
last_name: Vladar
orcid: 0000-0002-5985-7653
citation:
ama: de Vladar H. Amino acid fermentation at the origin of the genetic code. Biology
Direct. 2012;7. doi:10.1186/1745-6150-7-6
apa: de Vladar, H. (2012). Amino acid fermentation at the origin of the genetic
code. Biology Direct. BioMed Central. https://doi.org/10.1186/1745-6150-7-6
chicago: Vladar, Harold de. “Amino Acid Fermentation at the Origin of the Genetic
Code.” Biology Direct. BioMed Central, 2012. https://doi.org/10.1186/1745-6150-7-6.
ieee: H. de Vladar, “Amino acid fermentation at the origin of the genetic code,”
Biology Direct, vol. 7. BioMed Central, 2012.
ista: de Vladar H. 2012. Amino acid fermentation at the origin of the genetic code.
Biology Direct. 7, 6.
mla: de Vladar, Harold. “Amino Acid Fermentation at the Origin of the Genetic Code.”
Biology Direct, vol. 7, 6, BioMed Central, 2012, doi:10.1186/1745-6150-7-6.
short: H. de Vladar, Biology Direct 7 (2012).
date_created: 2018-12-11T12:01:46Z
date_published: 2012-02-10T00:00:00Z
date_updated: 2021-01-12T07:41:31Z
day: '10'
ddc:
- '570'
- '576'
department:
- _id: NiBa
doi: 10.1186/1745-6150-7-6
ec_funded: 1
file:
- access_level: open_access
checksum: e511e401e239ef608a7fd79b21a06d78
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:44Z
date_updated: 2020-07-14T12:46:02Z
file_id: '5166'
file_name: IST-2012-99-v1+1_1745-6150-7-6.pdf
file_size: 4099536
relation: main_file
file_date_updated: 2020-07-14T12:46:02Z
has_accepted_license: '1'
intvolume: ' 7'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Biology Direct
publication_status: published
publisher: BioMed Central
publist_id: '3518'
pubrep_id: '99'
quality_controlled: '1'
status: public
title: Amino acid fermentation at the origin of the genetic code
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2012'
...
---
_id: '3167'
article_type: letter_note
author:
- first_name: Michele
full_name: Weber, Michele
id: 3A3FC708-F248-11E8-B48F-1D18A9856A87
last_name: Weber
citation:
ama: Weber M. NextGen speaks 13 . Science. 2012;336(6077):32-34. doi:10.1126/science.336.6077.32
apa: Weber, M. (2012). NextGen speaks 13 . Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.336.6077.32
chicago: Weber, Michele. “NextGen Speaks 13 .” Science. American Association
for the Advancement of Science, 2012. https://doi.org/10.1126/science.336.6077.32.
ieee: M. Weber, “NextGen speaks 13 ,” Science, vol. 336, no. 6077. American
Association for the Advancement of Science, pp. 32–34, 2012.
ista: Weber M. 2012. NextGen speaks 13 . Science. 336(6077), 32–34.
mla: Weber, Michele. “NextGen Speaks 13 .” Science, vol. 336, no. 6077, American
Association for the Advancement of Science, 2012, pp. 32–34, doi:10.1126/science.336.6077.32.
short: M. Weber, Science 336 (2012) 32–34.
date_created: 2018-12-11T12:01:47Z
date_published: 2012-04-06T00:00:00Z
date_updated: 2021-01-12T07:41:32Z
day: '06'
department:
- _id: MiSi
doi: 10.1126/science.336.6077.32
external_id:
pmid:
- '22491839'
intvolume: ' 336'
issue: '6077'
language:
- iso: eng
month: '04'
oa_version: None
page: 32-34
pmid: 1
popular_science: '1'
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '3516'
status: public
title: 'NextGen speaks 13 '
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 336
year: '2012'
...
---
_id: '3168'
abstract:
- lang: eng
text: The induction of a signaling pathway is characterized by transient complex
formation and mutual posttranslational modification of proteins. To faithfully
capture this combinatorial process in a mathematical model is an important challenge
in systems biology. Exploiting the limited context on which most binding and modification
events are conditioned, attempts have been made to reduce the combinatorial complexity
by quotienting the reachable set of molecular species into species aggregates
while preserving the deterministic semantics of the thermodynamic limit. Recently,
we proposed a quotienting that also preserves the stochastic semantics and that
is complete in the sense that the semantics of individual species can be recovered
from the aggregate semantics. In this paper, we prove that this quotienting yields
a sufficient condition for weak lumpability (that is to say that the quotient
system is still Markovian for a given set of initial distributions) and that it
gives rise to a backward Markov bisimulation between the original and aggregated
transition system (which means that the conditional probability of being in a
given state in the original system knowing that we are in its equivalence class
is an invariant of the system). We illustrate the framework on a case study of
the epidermal growth factor (EGF)/insulin receptor crosstalk.
acknowledgement: "We would like to thank the anonymous reviewers for their comments
on the different versions of the paper. We would also like to thank Ferdinanda Camporesi
for her careful reading and the useful insights that she gave us about the paper.\r\nJérôme
Feret’s contribution was partially supported by the AbstractCell ANR-Chair of Excellence.
Heinz Koeppl’s research is supported by the Swiss National Science Foundation, grant
no. 200020-117975/1. Tatjana Petrov’s research is supported by SystemsX.ch (the
Swiss Initiative in Systems Biology)."
author:
- first_name: Jérôme
full_name: Feret, Jérôme
last_name: Feret
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Heinz
full_name: Koeppl, Heinz
last_name: Koeppl
- first_name: Tatjana
full_name: Petrov, Tatjana
id: 3D5811FC-F248-11E8-B48F-1D18A9856A87
last_name: Petrov
orcid: 0000-0002-9041-0905
citation:
ama: Feret J, Henzinger TA, Koeppl H, Petrov T. Lumpability abstractions of rule
based systems. Theoretical Computer Science. 2012;431:137-164. doi:10.1016/j.tcs.2011.12.059
apa: Feret, J., Henzinger, T. A., Koeppl, H., & Petrov, T. (2012). Lumpability
abstractions of rule based systems. Theoretical Computer Science. Elsevier.
https://doi.org/10.1016/j.tcs.2011.12.059
chicago: Feret, Jérôme, Thomas A Henzinger, Heinz Koeppl, and Tatjana Petrov. “Lumpability
Abstractions of Rule Based Systems.” Theoretical Computer Science. Elsevier,
2012. https://doi.org/10.1016/j.tcs.2011.12.059.
ieee: J. Feret, T. A. Henzinger, H. Koeppl, and T. Petrov, “Lumpability abstractions
of rule based systems,” Theoretical Computer Science, vol. 431. Elsevier,
pp. 137–164, 2012.
ista: Feret J, Henzinger TA, Koeppl H, Petrov T. 2012. Lumpability abstractions
of rule based systems. Theoretical Computer Science. 431, 137–164.
mla: Feret, Jérôme, et al. “Lumpability Abstractions of Rule Based Systems.” Theoretical
Computer Science, vol. 431, Elsevier, 2012, pp. 137–64, doi:10.1016/j.tcs.2011.12.059.
short: J. Feret, T.A. Henzinger, H. Koeppl, T. Petrov, Theoretical Computer Science
431 (2012) 137–164.
date_created: 2018-12-11T12:01:47Z
date_published: 2012-05-04T00:00:00Z
date_updated: 2023-02-23T11:39:40Z
day: '04'
department:
- _id: ToHe
doi: 10.1016/j.tcs.2011.12.059
intvolume: ' 431'
language:
- iso: eng
month: '05'
oa_version: None
page: 137 - 164
publication: Theoretical Computer Science
publication_status: published
publisher: Elsevier
publist_id: '3515'
pubrep_id: '73'
quality_controlled: '1'
related_material:
record:
- id: '3719'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Lumpability abstractions of rule based systems
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 431
year: '2012'
...
---
_id: '3242'
abstract:
- lang: eng
text: Due to the omnipresent risk of epidemics, insect societies have evolved sophisticated
disease defences at the individual and colony level. An intriguing yet little
understood phenomenon is that social contact to pathogen-exposed individuals reduces
susceptibility of previously naive nestmates to this pathogen. We tested whether
such social immunisation in Lasius ants against the entomopathogenic fungus Metarhizium
anisopliae is based on active upregulation of the immune system of nestmates following
contact to an infectious individual or passive protection via transfer of immune
effectors among group members—that is, active versus passive immunisation. We
found no evidence for involvement of passive immunisation via transfer of antimicrobials
among colony members. Instead, intensive allogrooming behaviour between naive
and pathogen-exposed ants before fungal conidia firmly attached to their cuticle
suggested passage of the pathogen from the exposed individuals to their nestmates.
By tracing fluorescence-labelled conidia we indeed detected frequent pathogen
transfer to the nestmates, where they caused low-level infections as revealed
by growth of small numbers of fungal colony forming units from their dissected
body content. These infections rarely led to death, but instead promoted an enhanced
ability to inhibit fungal growth and an active upregulation of immune genes involved
in antifungal defences (defensin and prophenoloxidase, PPO). Contrarily, there
was no upregulation of the gene cathepsin L, which is associated with antibacterial
and antiviral defences, and we found no increased antibacterial activity of nestmates
of fungus-exposed ants. This indicates that social immunisation after fungal exposure
is specific, similar to recent findings for individual-level immune priming in
invertebrates. Epidemiological modeling further suggests that active social immunisation
is adaptive, as it leads to faster elimination of the disease and lower death
rates than passive immunisation. Interestingly, humans have also utilised the
protective effect of low-level infections to fight smallpox by intentional transfer
of low pathogen doses (“variolation” or “inoculation”).
acknowledgement: Funding for this project was obtained by the German Research Foundation
DFG (http://www.dfg.de/en/index.jsp) as an Individual Research Grant (CR118/2-1
to SC) and the European Research Council (http://erc.europa.eu/) in form of two
ERC Starting Grants (ERC-2009-StG240371-SocialVaccines to SC and ERC-2010-StG259294-LatentCauses
to FJT). In addition, the Junge Akademie (Young Academy of the Berlin-Brandenburg
Academy of Sciences and Humanities and the National Academy of Sciences Leopoldina
(http://www.diejungeakademie.de/english/index.html) funded this joint Antnet project
of SC and FJT. The funders had no role in study design, data collection and analysis,
decision to publish, or preparation of the manuscript.
article_number: e1001300
author:
- first_name: Matthias
full_name: Konrad, Matthias
id: 46528076-F248-11E8-B48F-1D18A9856A87
last_name: Konrad
- first_name: Meghan
full_name: Vyleta, Meghan
id: 418901AA-F248-11E8-B48F-1D18A9856A87
last_name: Vyleta
- first_name: Fabian
full_name: Theis, Fabian
last_name: Theis
- first_name: Miriam
full_name: Stock, Miriam
id: 42462816-F248-11E8-B48F-1D18A9856A87
last_name: Stock
- first_name: Simon
full_name: Tragust, Simon
id: 35A7A418-F248-11E8-B48F-1D18A9856A87
last_name: Tragust
- first_name: Martina
full_name: Klatt, Martina
id: E60F29C6-E9AE-11E9-AF6E-D190C7302F38
last_name: Klatt
- first_name: Verena
full_name: Drescher, Verena
last_name: Drescher
- first_name: Carsten
full_name: Marr, Carsten
last_name: Marr
- first_name: Line V
full_name: Ugelvig, Line V
id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
last_name: Ugelvig
orcid: 0000-0003-1832-8883
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Konrad M, Vyleta M, Theis F, et al. Social transfer of pathogenic fungus promotes
active immunisation in ant colonies. PLoS Biology. 2012;10(4). doi:10.1371/journal.pbio.1001300
apa: Konrad, M., Vyleta, M., Theis, F., Stock, M., Tragust, S., Klatt, M., … Cremer,
S. (2012). Social transfer of pathogenic fungus promotes active immunisation in
ant colonies. PLoS Biology. Public Library of Science. https://doi.org/10.1371/journal.pbio.1001300
chicago: Konrad, Matthias, Meghan Vyleta, Fabian Theis, Miriam Stock, Simon Tragust,
Martina Klatt, Verena Drescher, Carsten Marr, Line V Ugelvig, and Sylvia Cremer.
“Social Transfer of Pathogenic Fungus Promotes Active Immunisation in Ant Colonies.”
PLoS Biology. Public Library of Science, 2012. https://doi.org/10.1371/journal.pbio.1001300.
ieee: M. Konrad et al., “Social transfer of pathogenic fungus promotes active
immunisation in ant colonies,” PLoS Biology, vol. 10, no. 4. Public Library
of Science, 2012.
ista: Konrad M, Vyleta M, Theis F, Stock M, Tragust S, Klatt M, Drescher V, Marr
C, Ugelvig LV, Cremer S. 2012. Social transfer of pathogenic fungus promotes active
immunisation in ant colonies. PLoS Biology. 10(4), e1001300.
mla: Konrad, Matthias, et al. “Social Transfer of Pathogenic Fungus Promotes Active
Immunisation in Ant Colonies.” PLoS Biology, vol. 10, no. 4, e1001300,
Public Library of Science, 2012, doi:10.1371/journal.pbio.1001300.
short: M. Konrad, M. Vyleta, F. Theis, M. Stock, S. Tragust, M. Klatt, V. Drescher,
C. Marr, L.V. Ugelvig, S. Cremer, PLoS Biology 10 (2012).
date_created: 2018-12-11T12:02:13Z
date_published: 2012-04-03T00:00:00Z
date_updated: 2023-02-23T14:07:11Z
day: '03'
ddc:
- '570'
- '579'
department:
- _id: SyCr
doi: 10.1371/journal.pbio.1001300
ec_funded: 1
file:
- access_level: open_access
checksum: 4ebacefd9fbab5c68adf829124115fd1
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:28Z
date_updated: 2020-07-14T12:46:04Z
file_id: '4689'
file_name: IST-2012-96-v1+1_journal.pbio.1001300.pdf
file_size: 674228
relation: main_file
file_date_updated: 2020-07-14T12:46:04Z
has_accepted_license: '1'
intvolume: ' 10'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 25DAF0B2-B435-11E9-9278-68D0E5697425
grant_number: CR-118/3-1
name: Host-Parasite Coevolution
- _id: 25DC711C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '243071'
name: 'Social Vaccination in Ant Colonies: from Individual Mechanisms to Society
Effects'
- _id: 25E0E184-B435-11E9-9278-68D0E5697425
name: Antnet
publication: PLoS Biology
publication_status: published
publisher: Public Library of Science
publist_id: '3434'
pubrep_id: '96'
quality_controlled: '1'
related_material:
record:
- id: '9755'
relation: research_data
status: public
scopus_import: 1
status: public
title: Social transfer of pathogenic fungus promotes active immunisation in ant colonies
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2012'
...
---
_id: '3243'
abstract:
- lang: eng
text: 'Wie wandelt sich das Berufsbild in Wissenschaftlichen Bibliotheken? Patrick
Danowski gibt seine Einschätzung ab. '
article_processing_charge: No
article_type: letter_note
author:
- first_name: Patrick
full_name: Danowski, Patrick
id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
last_name: Danowski
orcid: 0000-0002-6026-4409
citation:
ama: Danowski P. Zwischen Technologie und Information. Büchereiperspektiven.
2012;2012(1):11.
apa: Danowski, P. (2012). Zwischen Technologie und Information. Büchereiperspektiven.
Büchereiverband Österreichs.
chicago: Danowski, Patrick. “Zwischen Technologie und Information.” Büchereiperspektiven.
Büchereiverband Österreichs, 2012.
ieee: P. Danowski, “Zwischen Technologie und Information,” Büchereiperspektiven,
vol. 2012, no. 1. Büchereiverband Österreichs, p. 11, 2012.
ista: Danowski P. 2012. Zwischen Technologie und Information. Büchereiperspektiven.
2012(1), 11.
mla: Danowski, Patrick. “Zwischen Technologie und Information.” Büchereiperspektiven,
vol. 2012, no. 1, Büchereiverband Österreichs, 2012, p. 11.
short: P. Danowski, Büchereiperspektiven 2012 (2012) 11.
date_created: 2018-12-11T12:02:13Z
date_published: 2012-03-01T00:00:00Z
date_updated: 2023-10-16T10:40:18Z
day: '01'
department:
- _id: E-Lib
intvolume: ' 2012'
issue: '1'
language:
- iso: ger
main_file_link:
- open_access: '1'
url: https://www.bvoe.at/sites/default/files/2022-07/BP_1_12.pdf
month: '03'
oa: 1
oa_version: Published Version
page: '11'
popular_science: '1'
publication: Büchereiperspektiven
publication_identifier:
issn:
- 1607-7172
publication_status: published
publisher: Büchereiverband Österreichs
publist_id: '3433'
status: public
title: Zwischen Technologie und Information
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2012
year: '2012'
...
---
_id: '3244'
abstract:
- lang: eng
text: "Bibliothekare haben die Aufgabe, sich mit neuen Medienformen auseinanderzusetzen.\r\n"
article_processing_charge: No
article_type: letter_note
author:
- first_name: Patrick
full_name: Danowski, Patrick
id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
last_name: Danowski
orcid: 0000-0002-6026-4409
citation:
ama: Danowski P. Die Zeit des Abwartens ist vorbei! BuB - Forum Bibliothek und
Information. 2012;64(4):284.
apa: Danowski, P. (2012). Die Zeit des Abwartens ist vorbei! BuB - Forum Bibliothek
und Information. Fachzeitschrift des BIB – Berufsverband Information Bibliothek.
chicago: Danowski, Patrick. “Die Zeit des Abwartens ist vorbei!” BuB - Forum
Bibliothek und Information. Fachzeitschrift des BIB – Berufsverband Information
Bibliothek, 2012.
ieee: P. Danowski, “Die Zeit des Abwartens ist vorbei!,” BuB - Forum Bibliothek
und Information, vol. 64, no. 4. Fachzeitschrift des BIB – Berufsverband Information
Bibliothek, p. 284, 2012.
ista: Danowski P. 2012. Die Zeit des Abwartens ist vorbei! BuB - Forum Bibliothek
und Information. 64(4), 284.
mla: Danowski, Patrick. “Die Zeit des Abwartens ist vorbei!” BuB - Forum Bibliothek
und Information, vol. 64, no. 4, Fachzeitschrift des BIB – Berufsverband Information
Bibliothek, 2012, p. 284.
short: P. Danowski, BuB - Forum Bibliothek und Information 64 (2012) 284.
date_created: 2018-12-11T12:02:13Z
date_published: 2012-04-15T00:00:00Z
date_updated: 2023-10-16T10:19:14Z
day: '15'
department:
- _id: E-Lib
intvolume: ' 64'
issue: '4'
language:
- iso: ger
main_file_link:
- open_access: '1'
url: https://www.b-u-b.de/fileadmin/archiv/imports/pdf_files/2012/bub_2012_04_284.pdf
month: '04'
oa: 1
oa_version: Published Version
page: '284'
popular_science: '1'
publication: BuB - Forum Bibliothek und Information
publication_identifier:
issn:
- 1869 -1137
publication_status: published
publisher: Fachzeitschrift des BIB – Berufsverband Information Bibliothek
publist_id: '3432'
status: public
title: Die Zeit des Abwartens ist vorbei!
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 64
year: '2012'
...
---
_id: '3245'
abstract:
- lang: eng
text: How cells orchestrate their behavior during collective migration is a long-standing
question. Using magnetic tweezers to apply mechanical stimuli to Xenopus mesendoderm
cells, Weber etal. (2012) now reveal, in this issue of Developmental Cell, a cadherin-mediated
mechanosensitive response that promotes cell polarization and movement persistence
during the collective mesendoderm migration in gastrulation.
author:
- first_name: Martin
full_name: Behrndt, Martin
id: 3ECECA3A-F248-11E8-B48F-1D18A9856A87
last_name: Behrndt
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Behrndt M, Heisenberg C-PJ. Spurred by resistance mechanosensation in collective
migration. Developmental Cell. 2012;22(1):3-4. doi:10.1016/j.devcel.2011.12.018
apa: Behrndt, M., & Heisenberg, C.-P. J. (2012). Spurred by resistance mechanosensation
in collective migration. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2011.12.018
chicago: Behrndt, Martin, and Carl-Philipp J Heisenberg. “Spurred by Resistance
Mechanosensation in Collective Migration.” Developmental Cell. Cell Press,
2012. https://doi.org/10.1016/j.devcel.2011.12.018.
ieee: M. Behrndt and C.-P. J. Heisenberg, “Spurred by resistance mechanosensation
in collective migration,” Developmental Cell, vol. 22, no. 1. Cell Press,
pp. 3–4, 2012.
ista: Behrndt M, Heisenberg C-PJ. 2012. Spurred by resistance mechanosensation in
collective migration. Developmental Cell. 22(1), 3–4.
mla: Behrndt, Martin, and Carl-Philipp J. Heisenberg. “Spurred by Resistance Mechanosensation
in Collective Migration.” Developmental Cell, vol. 22, no. 1, Cell Press,
2012, pp. 3–4, doi:10.1016/j.devcel.2011.12.018.
short: M. Behrndt, C.-P.J. Heisenberg, Developmental Cell 22 (2012) 3–4.
date_created: 2018-12-11T12:02:14Z
date_published: 2012-01-17T00:00:00Z
date_updated: 2021-01-12T07:42:05Z
day: '17'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2011.12.018
intvolume: ' 22'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 3 - 4
publication: Developmental Cell
publication_status: published
publisher: Cell Press
publist_id: '3426'
quality_controlled: '1'
scopus_import: 1
status: public
title: Spurred by resistance mechanosensation in collective migration
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 22
year: '2012'
...
---
_id: '3246'
abstract:
- lang: eng
text: Visualizing and analyzing shape changes at various scales, ranging from single
molecules to whole organisms, are essential for understanding complex morphogenetic
processes, such as early embryonic development. Embryo morphogenesis relies on
the interplay between different tissues, the properties of which are again determined
by the interaction between their constituent cells. Cell interactions, on the
other hand, are controlled by various molecules, such as signaling and adhesion
molecules, which in order to exert their functions need to be spatiotemporally
organized within and between the interacting cells. In this review, we will focus
on the role of cell adhesion functioning at different scales to organize cell,
tissue and embryo morphogenesis. We will specifically ask how the subcellular
distribution of adhesion molecules controls the formation of cell-cell contacts,
how cell-cell contacts determine tissue shape, and how tissue interactions regulate
embryo morphogenesis.
acknowledgement: This review comes from a themed issue on Cell structure and dynamics
Edited by Jason Swedlow and Gaudenz Danuser
author:
- first_name: Vanessa
full_name: Barone, Vanessa
id: 419EECCC-F248-11E8-B48F-1D18A9856A87
last_name: Barone
orcid: 0000-0003-2676-3367
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Barone V, Heisenberg C-PJ. Cell adhesion in embryo morphogenesis. Current
Opinion in Cell Biology. 2012;24(1):148-153. doi:10.1016/j.ceb.2011.11.006
apa: Barone, V., & Heisenberg, C.-P. J. (2012). Cell adhesion in embryo morphogenesis.
Current Opinion in Cell Biology. Elsevier. https://doi.org/10.1016/j.ceb.2011.11.006
chicago: Barone, Vanessa, and Carl-Philipp J Heisenberg. “Cell Adhesion in Embryo
Morphogenesis.” Current Opinion in Cell Biology. Elsevier, 2012. https://doi.org/10.1016/j.ceb.2011.11.006.
ieee: V. Barone and C.-P. J. Heisenberg, “Cell adhesion in embryo morphogenesis,”
Current Opinion in Cell Biology, vol. 24, no. 1. Elsevier, pp. 148–153,
2012.
ista: Barone V, Heisenberg C-PJ. 2012. Cell adhesion in embryo morphogenesis. Current
Opinion in Cell Biology. 24(1), 148–153.
mla: Barone, Vanessa, and Carl-Philipp J. Heisenberg. “Cell Adhesion in Embryo Morphogenesis.”
Current Opinion in Cell Biology, vol. 24, no. 1, Elsevier, 2012, pp. 148–53,
doi:10.1016/j.ceb.2011.11.006.
short: V. Barone, C.-P.J. Heisenberg, Current Opinion in Cell Biology 24 (2012)
148–153.
date_created: 2018-12-11T12:02:14Z
date_published: 2012-02-01T00:00:00Z
date_updated: 2023-09-07T12:05:08Z
day: '01'
department:
- _id: CaHe
doi: 10.1016/j.ceb.2011.11.006
intvolume: ' 24'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 148 - 153
publication: Current Opinion in Cell Biology
publication_status: published
publisher: Elsevier
publist_id: '3423'
quality_controlled: '1'
related_material:
record:
- id: '961'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Cell adhesion in embryo morphogenesis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2012'
...
---
_id: '3247'
abstract:
- lang: eng
text: The Brazilian Merganser is a very rare and threatened species that nowadays
inhabits only a few protected areas and their surroundings in the Brazilian territory.
In order to estimate the remaining genetic diversity and population structure
in this species, two mitochondrial genes were sequenced in 39 individuals belonging
to two populations and in one individual collected in Argentina in 1950. We found
a highly significant divergence between two major remaining populations of Mergus
octosetaceus, which suggests a historical population structure in this species.
Furthermore, two deeply divergent lineages were found in a single location, which
could due to current or historical secondary contact. Based on the available genetic
data, we point out future directions which would contribute to design strategies
for conservation and management of this threatened species.
acknowledgement: "The present study received grants from FAPEMIG, CNPq, Petrobras
Ambiental and Fundação O Boticário de Conservação da Natureza, and followed all
ethical guidelines and legal requirements of Brazil for sampling and studying an
endangered species.\r\nWe thank the Specialist Work Group for the Conservation of
Brazilian Merganser for valuable discussions and opinions on this manuscript. We
also thank all the staff from Instituto Terra Brasilis and Funatura (Vivian S. Braz
and Gislaine Disconzi) for collecting the samples at Serra da Canastra and Chapada
dos Veadeiros, respectively; Dario A. Lijtmaerand and Pablo Tubaro for providing
the samples from Argentina, Bradley C. Livezey for sending copies of his papers,
and Geoff M. Hilton and Paulo de Tarso Z. Antas for useful suggestions that greatly
improved this manuscript."
author:
- first_name: Sibelle
full_name: Vilaça, Sibelle
last_name: Vilaça
- first_name: Rodrigo A
full_name: Fernandes Redondo, Rodrigo A
id: 409D5C96-F248-11E8-B48F-1D18A9856A87
last_name: Fernandes Redondo
orcid: 0000-0002-5837-2793
- first_name: Lívia
full_name: Lins, Lívia
last_name: Lins
- first_name: Fabrício
full_name: Santos, Fabrício
last_name: Santos
citation:
ama: Vilaça S, Fernandes Redondo RA, Lins L, Santos F. Remaining genetic diversity
in Brazilian Merganser (Mergus octosetaceus). Conservation Genetics. 2012;13(1):293-298.
doi:10.1007/s10592-011-0262-5
apa: Vilaça, S., Fernandes Redondo, R. A., Lins, L., & Santos, F. (2012). Remaining
genetic diversity in Brazilian Merganser (Mergus octosetaceus). Conservation
Genetics. Springer. https://doi.org/10.1007/s10592-011-0262-5
chicago: Vilaça, Sibelle, Rodrigo A Fernandes Redondo, Lívia Lins, and Fabrício
Santos. “Remaining Genetic Diversity in Brazilian Merganser (Mergus Octosetaceus).”
Conservation Genetics. Springer, 2012. https://doi.org/10.1007/s10592-011-0262-5.
ieee: S. Vilaça, R. A. Fernandes Redondo, L. Lins, and F. Santos, “Remaining genetic
diversity in Brazilian Merganser (Mergus octosetaceus),” Conservation Genetics,
vol. 13, no. 1. Springer, pp. 293–298, 2012.
ista: Vilaça S, Fernandes Redondo RA, Lins L, Santos F. 2012. Remaining genetic
diversity in Brazilian Merganser (Mergus octosetaceus). Conservation Genetics.
13(1), 293–298.
mla: Vilaça, Sibelle, et al. “Remaining Genetic Diversity in Brazilian Merganser
(Mergus Octosetaceus).” Conservation Genetics, vol. 13, no. 1, Springer,
2012, pp. 293–98, doi:10.1007/s10592-011-0262-5.
short: S. Vilaça, R.A. Fernandes Redondo, L. Lins, F. Santos, Conservation Genetics
13 (2012) 293–298.
date_created: 2018-12-11T12:02:15Z
date_published: 2012-02-01T00:00:00Z
date_updated: 2021-01-12T07:42:05Z
day: '01'
department:
- _id: JoBo
doi: 10.1007/s10592-011-0262-5
intvolume: ' 13'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 293 - 298
publication: Conservation Genetics
publication_status: published
publisher: Springer
publist_id: '3420'
quality_controlled: '1'
scopus_import: 1
status: public
title: Remaining genetic diversity in Brazilian Merganser (Mergus octosetaceus)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2012'
...
---
_id: '3248'
abstract:
- lang: eng
text: We describe RTblob, a high speed vision system that detects objects in cluttered
scenes based on their color and shape at a speed of over 800 frames/s. Because
the system is available as open-source software and relies only on off-the-shelf
PC hardware components, it can provide the basis for multiple application scenarios.
As an illustrative example, we show how RTblob can be used in a robotic table
tennis scenario to estimate ball trajectories through 3D space simultaneously
from four cameras images at a speed of 200 Hz.
article_processing_charge: No
article_type: original
author:
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Jan
full_name: Peters, Jan
last_name: Peters
citation:
ama: Lampert C, Peters J. Real-time detection of colored objects in multiple camera
streams with off-the-shelf hardware components. Journal of Real-Time Image
Processing. 2012;7(1):31-41. doi:10.1007/s11554-010-0168-3
apa: Lampert, C., & Peters, J. (2012). Real-time detection of colored objects
in multiple camera streams with off-the-shelf hardware components. Journal
of Real-Time Image Processing. Springer. https://doi.org/10.1007/s11554-010-0168-3
chicago: Lampert, Christoph, and Jan Peters. “Real-Time Detection of Colored Objects
in Multiple Camera Streams with off-the-Shelf Hardware Components.” Journal
of Real-Time Image Processing. Springer, 2012. https://doi.org/10.1007/s11554-010-0168-3.
ieee: C. Lampert and J. Peters, “Real-time detection of colored objects in multiple
camera streams with off-the-shelf hardware components,” Journal of Real-Time
Image Processing, vol. 7, no. 1. Springer, pp. 31–41, 2012.
ista: Lampert C, Peters J. 2012. Real-time detection of colored objects in multiple
camera streams with off-the-shelf hardware components. Journal of Real-Time Image
Processing. 7(1), 31–41.
mla: Lampert, Christoph, and Jan Peters. “Real-Time Detection of Colored Objects
in Multiple Camera Streams with off-the-Shelf Hardware Components.” Journal
of Real-Time Image Processing, vol. 7, no. 1, Springer, 2012, pp. 31–41, doi:10.1007/s11554-010-0168-3.
short: C. Lampert, J. Peters, Journal of Real-Time Image Processing 7 (2012) 31–41.
date_created: 2018-12-11T12:02:15Z
date_published: 2012-03-01T00:00:00Z
date_updated: 2022-05-24T08:05:40Z
day: '01'
ddc:
- '000'
department:
- _id: ChLa
doi: 10.1007/s11554-010-0168-3
file:
- access_level: open_access
checksum: 241be47ea50e81a283bcf4c45b07e8cc
content_type: application/pdf
creator: kschuh
date_created: 2019-02-12T10:52:25Z
date_updated: 2020-07-14T12:46:04Z
file_id: '5958'
file_name: 2012_Springer_Lampert.pdf
file_size: 2933187
relation: main_file
file_date_updated: 2020-07-14T12:46:04Z
has_accepted_license: '1'
intvolume: ' 7'
issue: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 31 - 41
publication: Journal of Real-Time Image Processing
publication_identifier:
eissn:
- 1861-8219
issn:
- 1861-8200
publication_status: published
publisher: Springer
publist_id: '3417'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Real-time detection of colored objects in multiple camera streams with off-the-shelf
hardware components
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2012'
...
---
_id: '3249'
abstract:
- lang: eng
text: Boolean notions of correctness are formalized by preorders on systems. Quantitative
measures of correctness can be formalized by real-valued distance functions between
systems, where the distance between implementation and specification provides
a measure of "fit" or "desirability". We extend the simulation
preorder to the quantitative setting by making each player of a simulation game
pay a certain price for her choices. We use the resulting games with quantitative
objectives to define three different simulation distances. The correctness distance
measures how much the specification must be changed in order to be satisfied by
the implementation. The coverage distance measures how much the implementation
restricts the degrees of freedom offered by the specification. The robustness
distance measures how much a system can deviate from the implementation description
without violating the specification. We consider these distances for safety as
well as liveness specifications. The distances can be computed in polynomial time
for safety specifications, and for liveness specifications given by weak fairness
constraints. We show that the distance functions satisfy the triangle inequality,
that the distance between two systems does not increase under parallel composition
with a third system, and that the distance between two systems can be bounded
from above and below by distances between abstractions of the two systems. These
properties suggest that our simulation distances provide an appropriate basis
for a quantitative theory of discrete systems. We also demonstrate how the robustness
distance can be used to measure how many transmission errors are tolerated by
error correcting codes.
acknowledgement: This work was partially supported by the ERC Advanced Grant QUAREM,
the FWF NFN Grant S11402-N23 (RiSE), the European Union project COMBEST and the
European Network of Excellence Artist Design.
author:
- first_name: Pavol
full_name: Cerny, Pavol
id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
last_name: Cerny
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Arjun
full_name: Radhakrishna, Arjun
id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
last_name: Radhakrishna
citation:
ama: Cerny P, Henzinger TA, Radhakrishna A. Simulation distances. Theoretical
Computer Science. 2012;413(1):21-35. doi:10.1016/j.tcs.2011.08.002
apa: Cerny, P., Henzinger, T. A., & Radhakrishna, A. (2012). Simulation distances.
Theoretical Computer Science. Elsevier. https://doi.org/10.1016/j.tcs.2011.08.002
chicago: Cerny, Pavol, Thomas A Henzinger, and Arjun Radhakrishna. “Simulation Distances.”
Theoretical Computer Science. Elsevier, 2012. https://doi.org/10.1016/j.tcs.2011.08.002.
ieee: P. Cerny, T. A. Henzinger, and A. Radhakrishna, “Simulation distances,” Theoretical
Computer Science, vol. 413, no. 1. Elsevier, pp. 21–35, 2012.
ista: Cerny P, Henzinger TA, Radhakrishna A. 2012. Simulation distances. Theoretical
Computer Science. 413(1), 21–35.
mla: Cerny, Pavol, et al. “Simulation Distances.” Theoretical Computer Science,
vol. 413, no. 1, Elsevier, 2012, pp. 21–35, doi:10.1016/j.tcs.2011.08.002.
short: P. Cerny, T.A. Henzinger, A. Radhakrishna, Theoretical Computer Science 413
(2012) 21–35.
date_created: 2018-12-11T12:02:15Z
date_published: 2012-01-06T00:00:00Z
date_updated: 2023-02-23T12:24:04Z
day: '06'
department:
- _id: ToHe
doi: 10.1016/j.tcs.2011.08.002
ec_funded: 1
intvolume: ' 413'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 21 - 35
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25EFB36C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '215543'
name: COMponent-Based Embedded Systems design Techniques
- _id: 25F1337C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '214373'
name: Design for Embedded Systems
publication: Theoretical Computer Science
publication_status: published
publisher: Elsevier
publist_id: '3408'
pubrep_id: '42'
quality_controlled: '1'
related_material:
record:
- id: '4393'
relation: earlier_version
status: public
- id: '5389'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Simulation distances
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 413
year: '2012'
...
---
_id: '3250'
abstract:
- lang: eng
text: The Learning Parity with Noise (LPN) problem has recently found many applications
in cryptography as the hardness assumption underlying the constructions of "provably
secure" cryptographic schemes like encryption or authentication protocols.
Being provably secure means that the scheme comes with a proof showing that the
existence of an efficient adversary against the scheme implies that the underlying
hardness assumption is wrong. LPN based schemes are appealing for theoretical
and practical reasons. On the theoretical side, LPN based schemes offer a very
strong security guarantee. The LPN problem is equivalent to the problem of decoding
random linear codes, a problem that has been extensively studied in the last half
century. The fastest known algorithms run in exponential time and unlike most
number-theoretic problems used in cryptography, the LPN problem does not succumb
to known quantum algorithms. On the practical side, LPN based schemes are often
extremely simple and efficient in terms of code-size as well as time and space
requirements. This makes them prime candidates for light-weight devices like RFID
tags, which are too weak to implement standard cryptographic primitives like the
AES block-cipher. This talk will be a gentle introduction to provable security
using simple LPN based schemes as examples. Starting from pseudorandom generators
and symmetric key encryption, over secret-key authentication protocols, and, if
time admits, touching on recent constructions of public-key identification, commitments
and zero-knowledge proofs.
alternative_title:
- LNCS
author:
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Pietrzak KZ. Cryptography from learning parity with noise. In: Vol 7147. Springer;
2012:99-114. doi:10.1007/978-3-642-27660-6_9'
apa: 'Pietrzak, K. Z. (2012). Cryptography from learning parity with noise (Vol.
7147, pp. 99–114). Presented at the SOFSEM: Current Trends in Theory and Practice
of Computer Science, Špindlerův Mlýn, Czech Republic: Springer. https://doi.org/10.1007/978-3-642-27660-6_9'
chicago: Pietrzak, Krzysztof Z. “Cryptography from Learning Parity with Noise,”
7147:99–114. Springer, 2012. https://doi.org/10.1007/978-3-642-27660-6_9.
ieee: 'K. Z. Pietrzak, “Cryptography from learning parity with noise,” presented
at the SOFSEM: Current Trends in Theory and Practice of Computer Science, Špindlerův
Mlýn, Czech Republic, 2012, vol. 7147, pp. 99–114.'
ista: 'Pietrzak KZ. 2012. Cryptography from learning parity with noise. SOFSEM:
Current Trends in Theory and Practice of Computer Science, LNCS, vol. 7147, 99–114.'
mla: Pietrzak, Krzysztof Z. Cryptography from Learning Parity with Noise.
Vol. 7147, Springer, 2012, pp. 99–114, doi:10.1007/978-3-642-27660-6_9.
short: K.Z. Pietrzak, in:, Springer, 2012, pp. 99–114.
conference:
end_date: 2012-01-27
location: Špindlerův Mlýn, Czech Republic
name: 'SOFSEM: Current Trends in Theory and Practice of Computer Science'
start_date: 2012-01-21
date_created: 2018-12-11T12:02:15Z
date_published: 2012-02-19T00:00:00Z
date_updated: 2021-01-12T07:42:07Z
day: '19'
department:
- _id: KrPi
doi: 10.1007/978-3-642-27660-6_9
intvolume: ' 7147'
language:
- iso: eng
month: '02'
oa_version: None
page: 99 - 114
publication_status: published
publisher: Springer
publist_id: '3407'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cryptography from learning parity with noise
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7147
year: '2012'
...
---
_id: '3251'
abstract:
- lang: eng
text: Many infinite state systems can be seen as well-structured transition systems
(WSTS), i.e., systems equipped with a well-quasi-ordering on states that is also
a simulation relation. WSTS are an attractive target for formal analysis because
there exist generic algorithms that decide interesting verification problems for
this class. Among the most popular algorithms are acceleration-based forward analyses
for computing the covering set. Termination of these algorithms can only be guaranteed
for flattable WSTS. Yet, many WSTS of practical interest are not flattable and
the question whether any given WSTS is flattable is itself undecidable. We therefore
propose an analysis that computes the covering set and captures the essence of
acceleration-based algorithms, but sacrifices precision for guaranteed termination.
Our analysis is an abstract interpretation whose abstract domain builds on the
ideal completion of the well-quasi-ordered state space, and a widening operator
that mimics acceleration and controls the loss of precision of the analysis. We
present instances of our framework for various classes of WSTS. Our experience
with a prototype implementation indicates that, despite the inherent precision
loss, our analysis often computes the precise covering set of the analyzed system.
acknowledgement: This research was supported in part by the European Research Council
(ERC) Advanced Investigator Grant QUAREM and by the Austrian Science Fund (FWF)
project S11402-N23.
alternative_title:
- LNCS
author:
- first_name: Damien
full_name: Zufferey, Damien
id: 4397AC76-F248-11E8-B48F-1D18A9856A87
last_name: Zufferey
orcid: 0000-0002-3197-8736
- first_name: Thomas
full_name: Wies, Thomas
id: 447BFB88-F248-11E8-B48F-1D18A9856A87
last_name: Wies
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: 'Zufferey D, Wies T, Henzinger TA. Ideal abstractions for well structured transition
systems. In: Vol 7148. Springer; 2012:445-460. doi:10.1007/978-3-642-27940-9_29'
apa: 'Zufferey, D., Wies, T., & Henzinger, T. A. (2012). Ideal abstractions
for well structured transition systems (Vol. 7148, pp. 445–460). Presented at
the VMCAI: Verification, Model Checking and Abstract Interpretation, Philadelphia,
PA, USA: Springer. https://doi.org/10.1007/978-3-642-27940-9_29'
chicago: Zufferey, Damien, Thomas Wies, and Thomas A Henzinger. “Ideal Abstractions
for Well Structured Transition Systems,” 7148:445–60. Springer, 2012. https://doi.org/10.1007/978-3-642-27940-9_29.
ieee: 'D. Zufferey, T. Wies, and T. A. Henzinger, “Ideal abstractions for well structured
transition systems,” presented at the VMCAI: Verification, Model Checking and
Abstract Interpretation, Philadelphia, PA, USA, 2012, vol. 7148, pp. 445–460.'
ista: 'Zufferey D, Wies T, Henzinger TA. 2012. Ideal abstractions for well structured
transition systems. VMCAI: Verification, Model Checking and Abstract Interpretation,
LNCS, vol. 7148, 445–460.'
mla: Zufferey, Damien, et al. Ideal Abstractions for Well Structured Transition
Systems. Vol. 7148, Springer, 2012, pp. 445–60, doi:10.1007/978-3-642-27940-9_29.
short: D. Zufferey, T. Wies, T.A. Henzinger, in:, Springer, 2012, pp. 445–460.
conference:
end_date: 2012-01-24
location: Philadelphia, PA, USA
name: 'VMCAI: Verification, Model Checking and Abstract Interpretation'
start_date: 2012-01-22
date_created: 2018-12-11T12:02:16Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2023-09-07T11:36:36Z
day: '01'
ddc:
- '000'
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-27940-9_29
ec_funded: 1
file:
- access_level: open_access
checksum: f2f0d55efa32309ad1fe65a5fcaad90c
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:09:35Z
date_updated: 2020-07-14T12:46:05Z
file_id: '4759'
file_name: IST-2012-100-v1+1_Ideal_abstractions_for_well-structured_transition_systems.pdf
file_size: 217104
relation: main_file
file_date_updated: 2020-07-14T12:46:05Z
has_accepted_license: '1'
intvolume: ' 7148'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 445 - 460
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication_status: published
publisher: Springer
publist_id: '3406'
pubrep_id: '100'
quality_controlled: '1'
related_material:
record:
- id: '1405'
relation: dissertation_contains
status: public
status: public
title: Ideal abstractions for well structured transition systems
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7148
year: '2012'
...
---
_id: '3252'
abstract:
- lang: eng
text: 'We study the automatic synthesis of fair non-repudiation protocols, a class
of fair exchange protocols, used for digital contract signing. First, we show
how to specify the objectives of the participating agents, the trusted third party
(TTP) and the protocols as path formulas in Linear Temporal Logic (LTL) and prove
that the satisfaction of the objectives of the agents and the TTP imply satisfaction
of the protocol objectives. We then show that weak (co-operative) co-synthesis
and classical (strictly competitive) co-synthesis fail in synthesizing these protocols,
whereas assume-guarantee synthesis (AGS) succeeds. We demonstrate the success
of assume-guarantee synthesis as follows: (a) any solution of assume-guarantee
synthesis is attack-free; no subset of participants can violate the objectives
of the other participants without violating their own objectives; (b) the Asokan-Shoup-Waidner
(ASW) certified mail protocol that has known vulnerabilities is not a solution
of AGS; and (c) the Kremer-Markowitch (KM) non-repudiation protocol is a solution
of AGS. To our knowledge this is the first application of synthesis to fair non-repudiation
protocols, and our results show how synthesis can generate correct protocols and
automatically discover vulnerabilities. The solution to assume-guarantee synthesis
can be computed efficiently as the secure equilibrium solution of three-player
graph games. © 2012 Springer-Verlag.'
acknowledgement: "The research was supported by Austrian Science Fund (FWF) Grant
No P 23499-N23 (Modern Graph Algorithmic Techniques in Formal Verification), FWF
NFN Grant No S11407-N23 (RiSE), ERC Start grant (279307: Graph Games), and Microsoft
faculty fellows award.\r\nThe authors would like to thank Avik Chaudhuri for his
invaluable help and feedback."
alternative_title:
- LNCS
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Vishwanath
full_name: Raman, Vishwanath
last_name: Raman
citation:
ama: 'Chatterjee K, Raman V. Synthesizing protocols for digital contract signing.
In: Vol 7148. Springer; 2012:152-168. doi:10.1007/978-3-642-27940-9_11'
apa: 'Chatterjee, K., & Raman, V. (2012). Synthesizing protocols for digital
contract signing (Vol. 7148, pp. 152–168). Presented at the VMCAI: Verification,
Model Checking and Abstract Interpretation, Philadelphia, PA, USA: Springer. https://doi.org/10.1007/978-3-642-27940-9_11'
chicago: Chatterjee, Krishnendu, and Vishwanath Raman. “Synthesizing Protocols for
Digital Contract Signing,” 7148:152–68. Springer, 2012. https://doi.org/10.1007/978-3-642-27940-9_11.
ieee: 'K. Chatterjee and V. Raman, “Synthesizing protocols for digital contract
signing,” presented at the VMCAI: Verification, Model Checking and Abstract Interpretation,
Philadelphia, PA, USA, 2012, vol. 7148, pp. 152–168.'
ista: 'Chatterjee K, Raman V. 2012. Synthesizing protocols for digital contract
signing. VMCAI: Verification, Model Checking and Abstract Interpretation, LNCS,
vol. 7148, 152–168.'
mla: Chatterjee, Krishnendu, and Vishwanath Raman. Synthesizing Protocols for
Digital Contract Signing. Vol. 7148, Springer, 2012, pp. 152–68, doi:10.1007/978-3-642-27940-9_11.
short: K. Chatterjee, V. Raman, in:, Springer, 2012, pp. 152–168.
conference:
end_date: 2012-01-24
location: Philadelphia, PA, USA
name: 'VMCAI: Verification, Model Checking and Abstract Interpretation'
start_date: 2012-01-22
date_created: 2018-12-11T12:02:16Z
date_published: 2012-01-20T00:00:00Z
date_updated: 2021-01-12T07:42:08Z
day: '20'
department:
- _id: KrCh
doi: 10.1007/978-3-642-27940-9_11
ec_funded: 1
intvolume: ' 7148'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1004.2697
month: '01'
oa: 1
oa_version: Preprint
page: 152 - 168
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication_status: published
publisher: Springer
publist_id: '3405'
quality_controlled: '1'
scopus_import: 1
status: public
title: Synthesizing protocols for digital contract signing
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7148
year: '2012'
...
---
_id: '3253'
abstract:
- lang: eng
text: We describe a framework for reasoning about programs with lists carrying integer
numerical data. We use abstract domains to describe and manipulate complex constraints
on configurations of these programs mixing constraints on the shape of the heap,
sizes of the lists, on the multisets of data stored in these lists, and on the
data at their different positions. Moreover, we provide powerful techniques for
automatic validation of Hoare-triples and invariant checking, as well as for automatic
synthesis of invariants and procedure summaries using modular inter-procedural
analysis. The approach has been implemented in a tool called Celia and experimented
successfully on a large benchmark of programs.
acknowledgement: This work was partly supported by the French National Research Agency
(ANR) project Veridyc (ANR-09-SEGI-016).
alternative_title:
- LNCS
author:
- first_name: Ahmed
full_name: Bouajjani, Ahmed
last_name: Bouajjani
- first_name: Cezara
full_name: Dragoi, Cezara
id: 2B2B5ED0-F248-11E8-B48F-1D18A9856A87
last_name: Dragoi
- first_name: Constantin
full_name: Enea, Constantin
last_name: Enea
- first_name: Mihaela
full_name: Sighireanu, Mihaela
last_name: Sighireanu
citation:
ama: 'Bouajjani A, Dragoi C, Enea C, Sighireanu M. Abstract domains for automated
reasoning about list manipulating programs with infinite data. In: Vol 7148. Springer;
2012:1-22. doi:10.1007/978-3-642-27940-9_1'
apa: 'Bouajjani, A., Dragoi, C., Enea, C., & Sighireanu, M. (2012). Abstract
domains for automated reasoning about list manipulating programs with infinite
data (Vol. 7148, pp. 1–22). Presented at the VMCAI: Verification, Model Checking
and Abstract Interpretation, Philadelphia, PA, USA: Springer. https://doi.org/10.1007/978-3-642-27940-9_1'
chicago: Bouajjani, Ahmed, Cezara Dragoi, Constantin Enea, and Mihaela Sighireanu.
“Abstract Domains for Automated Reasoning about List Manipulating Programs with
Infinite Data,” 7148:1–22. Springer, 2012. https://doi.org/10.1007/978-3-642-27940-9_1.
ieee: 'A. Bouajjani, C. Dragoi, C. Enea, and M. Sighireanu, “Abstract domains for
automated reasoning about list manipulating programs with infinite data,” presented
at the VMCAI: Verification, Model Checking and Abstract Interpretation, Philadelphia,
PA, USA, 2012, vol. 7148, pp. 1–22.'
ista: 'Bouajjani A, Dragoi C, Enea C, Sighireanu M. 2012. Abstract domains for automated
reasoning about list manipulating programs with infinite data. VMCAI: Verification,
Model Checking and Abstract Interpretation, LNCS, vol. 7148, 1–22.'
mla: Bouajjani, Ahmed, et al. Abstract Domains for Automated Reasoning about
List Manipulating Programs with Infinite Data. Vol. 7148, Springer, 2012,
pp. 1–22, doi:10.1007/978-3-642-27940-9_1.
short: A. Bouajjani, C. Dragoi, C. Enea, M. Sighireanu, in:, Springer, 2012, pp.
1–22.
conference:
end_date: 2012-01-24
location: Philadelphia, PA, USA
name: 'VMCAI: Verification, Model Checking and Abstract Interpretation'
start_date: 2012-01-22
date_created: 2018-12-11T12:02:17Z
date_published: 2012-02-26T00:00:00Z
date_updated: 2021-01-12T07:42:09Z
day: '26'
department:
- _id: ToHe
doi: 10.1007/978-3-642-27940-9_1
intvolume: ' 7148'
language:
- iso: eng
month: '02'
oa_version: None
page: 1 - 22
publication_status: published
publisher: Springer
publist_id: '3404'
quality_controlled: '1'
status: public
title: Abstract domains for automated reasoning about list manipulating programs with
infinite data
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7148
year: '2012'
...
---
_id: '3254'
abstract:
- lang: eng
text: 'The theory of graph games with ω-regular winning conditions is the foundation
for modeling and synthesizing reactive processes. In the case of stochastic reactive
processes, the corresponding stochastic graph games have three players, two of
them (System and Environment) behaving adversarially, and the third (Uncertainty)
behaving probabilistically. We consider two problems for stochastic graph games:
the qualitative problem asks for the set of states from which a player can win
with probability 1 (almost-sure winning); and the quantitative problem asks for
the maximal probability of winning (optimal winning) from each state. We consider
ω-regular winning conditions formalized as Müller winning conditions. We present
optimal memory bounds for pure (deterministic) almost-sure winning and optimal
winning strategies in stochastic graph games with Müller winning conditions. We
also study the complexity of stochastic Müller games and show that both the qualitative
and quantitative analysis problems are PSPACE-complete. Our results are relevant
in synthesis of stochastic reactive processes.'
acknowledgement: 'The research was supported by Austrian Science Fund (FWF) Grant
No. P 23499-N23, FWF NFN Grant No. S11407-N23 (RiSE), ERC Start grant (279307: Graph
Games), and Microsoft faculty fellows award.'
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Chatterjee K. The complexity of stochastic Müller games. Information and
Computation. 2012;211:29-48. doi:10.1016/j.ic.2011.11.004
apa: Chatterjee, K. (2012). The complexity of stochastic Müller games. Information
and Computation. Elsevier. https://doi.org/10.1016/j.ic.2011.11.004
chicago: Chatterjee, Krishnendu. “The Complexity of Stochastic Müller Games.” Information
and Computation. Elsevier, 2012. https://doi.org/10.1016/j.ic.2011.11.004.
ieee: K. Chatterjee, “The complexity of stochastic Müller games,” Information
and Computation, vol. 211. Elsevier, pp. 29–48, 2012.
ista: Chatterjee K. 2012. The complexity of stochastic Müller games. Information
and Computation. 211, 29–48.
mla: Chatterjee, Krishnendu. “The Complexity of Stochastic Müller Games.” Information
and Computation, vol. 211, Elsevier, 2012, pp. 29–48, doi:10.1016/j.ic.2011.11.004.
short: K. Chatterjee, Information and Computation 211 (2012) 29–48.
date_created: 2018-12-11T12:02:17Z
date_published: 2012-02-01T00:00:00Z
date_updated: 2021-01-12T07:42:09Z
day: '01'
department:
- _id: KrCh
doi: 10.1016/j.ic.2011.11.004
ec_funded: 1
intvolume: ' 211'
language:
- iso: eng
main_file_link:
- url: http://arise.or.at/pubpdf/The_complexity_of_stochastic_M___u_ller_games.pdf
month: '02'
oa_version: None
page: 29 - 48
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Information and Computation
publication_status: published
publisher: Elsevier
publist_id: '3403'
quality_controlled: '1'
scopus_import: 1
status: public
title: The complexity of stochastic Müller games
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 211
year: '2012'
...
---
_id: '3255'
abstract:
- lang: eng
text: In this paper we survey results of two-player games on graphs and Markov decision
processes with parity, mean-payoff and energy objectives, and the combination
of mean-payoff and energy objectives with parity objectives. These problems have
applications in verification and synthesis of reactive systems in resource-constrained
environments.
acknowledgement: This work was partially supported by FWF NFN Grant S11407-N23 (RiSE)
and a Microsoft faculty fellowship.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
citation:
ama: 'Chatterjee K, Doyen L. Games and Markov decision processes with mean payoff
parity and energy parity objectives. In: Vol 7119. Springer; 2012:37-46. doi:10.1007/978-3-642-25929-6_3'
apa: 'Chatterjee, K., & Doyen, L. (2012). Games and Markov decision processes
with mean payoff parity and energy parity objectives (Vol. 7119, pp. 37–46). Presented
at the MEMICS: Mathematical and Engineering Methods in Computer Science, Lednice,
Czech Republic: Springer. https://doi.org/10.1007/978-3-642-25929-6_3'
chicago: Chatterjee, Krishnendu, and Laurent Doyen. “Games and Markov Decision Processes
with Mean Payoff Parity and Energy Parity Objectives,” 7119:37–46. Springer, 2012.
https://doi.org/10.1007/978-3-642-25929-6_3.
ieee: 'K. Chatterjee and L. Doyen, “Games and Markov decision processes with mean
payoff parity and energy parity objectives,” presented at the MEMICS: Mathematical
and Engineering Methods in Computer Science, Lednice, Czech Republic, 2012, vol.
7119, pp. 37–46.'
ista: 'Chatterjee K, Doyen L. 2012. Games and Markov decision processes with mean
payoff parity and energy parity objectives. MEMICS: Mathematical and Engineering
Methods in Computer Science, LNCS, vol. 7119, 37–46.'
mla: Chatterjee, Krishnendu, and Laurent Doyen. Games and Markov Decision Processes
with Mean Payoff Parity and Energy Parity Objectives. Vol. 7119, Springer,
2012, pp. 37–46, doi:10.1007/978-3-642-25929-6_3.
short: K. Chatterjee, L. Doyen, in:, Springer, 2012, pp. 37–46.
conference:
end_date: 2011-10-16
location: Lednice, Czech Republic
name: 'MEMICS: Mathematical and Engineering Methods in Computer Science'
start_date: 2011-10-14
date_created: 2018-12-11T12:02:17Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2021-01-12T07:42:10Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/978-3-642-25929-6_3
file:
- access_level: open_access
checksum: eed2cc1e76b160418c977e76e8899a60
content_type: application/pdf
creator: dernst
date_created: 2020-05-15T12:53:12Z
date_updated: 2020-07-14T12:46:05Z
file_id: '7863'
file_name: 2012_MEMICS_Chatterjee.pdf
file_size: 114060
relation: main_file
file_date_updated: 2020-07-14T12:46:05Z
has_accepted_license: '1'
intvolume: ' 7119'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 37 - 46
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication_status: published
publisher: Springer
publist_id: '3400'
quality_controlled: '1'
scopus_import: 1
status: public
title: Games and Markov decision processes with mean payoff parity and energy parity
objectives
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7119
year: '2012'
...
---
_id: '3256'
abstract:
- lang: eng
text: We use a distortion to define the dual complex of a cubical subdivision of
ℝ n as an n-dimensional subcomplex of the nerve of the set of n-cubes. Motivated
by the topological analysis of high-dimensional digital image data, we consider
such subdivisions defined by generalizations of quad- and oct-trees to n dimensions.
Assuming the subdivision is balanced, we show that mapping each vertex to the
center of the corresponding n-cube gives a geometric realization of the dual complex
in ℝ n.
acknowledgement: This research is partially supported by the Defense Advanced Research
Projects Agency (DARPA) under grants HR0011-05-1-0057 and HR0011-09-0065 as well
as the National Science Foundation (NSF) under grant DBI-0820624.
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Michael
full_name: Kerber, Michael
id: 36E4574A-F248-11E8-B48F-1D18A9856A87
last_name: Kerber
orcid: 0000-0002-8030-9299
citation:
ama: Edelsbrunner H, Kerber M. Dual complexes of cubical subdivisions of ℝn. Discrete
& Computational Geometry. 2012;47(2):393-414. doi:10.1007/s00454-011-9382-4
apa: Edelsbrunner, H., & Kerber, M. (2012). Dual complexes of cubical subdivisions
of ℝn. Discrete & Computational Geometry. Springer. https://doi.org/10.1007/s00454-011-9382-4
chicago: Edelsbrunner, Herbert, and Michael Kerber. “Dual Complexes of Cubical Subdivisions
of ℝn.” Discrete & Computational Geometry. Springer, 2012. https://doi.org/10.1007/s00454-011-9382-4.
ieee: H. Edelsbrunner and M. Kerber, “Dual complexes of cubical subdivisions of
ℝn,” Discrete & Computational Geometry, vol. 47, no. 2. Springer, pp.
393–414, 2012.
ista: Edelsbrunner H, Kerber M. 2012. Dual complexes of cubical subdivisions of
ℝn. Discrete & Computational Geometry. 47(2), 393–414.
mla: Edelsbrunner, Herbert, and Michael Kerber. “Dual Complexes of Cubical Subdivisions
of ℝn.” Discrete & Computational Geometry, vol. 47, no. 2, Springer,
2012, pp. 393–414, doi:10.1007/s00454-011-9382-4.
short: H. Edelsbrunner, M. Kerber, Discrete & Computational Geometry 47 (2012)
393–414.
date_created: 2018-12-11T12:02:17Z
date_published: 2012-03-01T00:00:00Z
date_updated: 2021-01-12T07:42:10Z
day: '01'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1007/s00454-011-9382-4
file:
- access_level: open_access
checksum: 76486f3b2c9e7fd81342f3832ca387e7
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:15Z
date_updated: 2020-07-14T12:46:05Z
file_id: '4675'
file_name: IST-2016-543-v1+1_2012-J-08-HierarchyCubeComplex.pdf
file_size: 203636
relation: main_file
file_date_updated: 2020-07-14T12:46:05Z
has_accepted_license: '1'
intvolume: ' 47'
issue: '2'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 393 - 414
publication: Discrete & Computational Geometry
publication_status: published
publisher: Springer
publist_id: '3398'
pubrep_id: '543'
quality_controlled: '1'
scopus_import: 1
status: public
title: Dual complexes of cubical subdivisions of ℝn
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 47
year: '2012'
...
---
_id: '3257'
abstract:
- lang: eng
text: Consider a convex relaxation f̂ of a pseudo-Boolean function f. We say that
the relaxation is totally half-integral if f̂(x) is a polyhedral function with
half-integral extreme points x, and this property is preserved after adding an
arbitrary combination of constraints of the form x i=x j, x i=1-x j, and x i=γ
where γ∈{0,1,1/2} is a constant. A well-known example is the roof duality relaxation
for quadratic pseudo-Boolean functions f. We argue that total half-integrality
is a natural requirement for generalizations of roof duality to arbitrary pseudo-Boolean
functions. Our contributions are as follows. First, we provide a complete characterization
of totally half-integral relaxations f̂ by establishing a one-to-one correspondence
with bisubmodular functions. Second, we give a new characterization of bisubmodular
functions. Finally, we show some relationships between general totally half-integral
relaxations and relaxations based on the roof duality. On the conceptual level,
our results show that bisubmodular functions provide a natural generalization
of the roof duality approach to higher-order terms. This can be viewed as a non-submodular
analogue of the fact that submodular functions generalize the s-t minimum cut
problem with non-negative weights to higher-order terms.
arxiv: 1
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: Kolmogorov V. Generalized roof duality and bisubmodular functions. Discrete
Applied Mathematics. 2012;160(4-5):416-426. doi:10.1016/j.dam.2011.10.026
apa: Kolmogorov, V. (2012). Generalized roof duality and bisubmodular functions.
Discrete Applied Mathematics. Elsevier. https://doi.org/10.1016/j.dam.2011.10.026
chicago: Kolmogorov, Vladimir. “Generalized Roof Duality and Bisubmodular Functions.”
Discrete Applied Mathematics. Elsevier, 2012. https://doi.org/10.1016/j.dam.2011.10.026.
ieee: V. Kolmogorov, “Generalized roof duality and bisubmodular functions,” Discrete
Applied Mathematics, vol. 160, no. 4–5. Elsevier, pp. 416–426, 2012.
ista: Kolmogorov V. 2012. Generalized roof duality and bisubmodular functions. Discrete
Applied Mathematics. 160(4–5), 416–426.
mla: Kolmogorov, Vladimir. “Generalized Roof Duality and Bisubmodular Functions.”
Discrete Applied Mathematics, vol. 160, no. 4–5, Elsevier, 2012, pp. 416–26,
doi:10.1016/j.dam.2011.10.026.
short: V. Kolmogorov, Discrete Applied Mathematics 160 (2012) 416–426.
date_created: 2018-12-11T12:02:18Z
date_published: 2012-03-01T00:00:00Z
date_updated: 2023-02-23T11:04:49Z
day: '01'
department:
- _id: VlKo
doi: 10.1016/j.dam.2011.10.026
external_id:
arxiv:
- '1005.2305'
intvolume: ' 160'
issue: 4-5
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1005.2305
month: '03'
oa: 1
oa_version: Preprint
page: 416 - 426
publication: Discrete Applied Mathematics
publication_status: published
publisher: Elsevier
publist_id: '3397'
quality_controlled: '1'
related_material:
record:
- id: '2934'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Generalized roof duality and bisubmodular functions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 160
year: '2012'
...
---
_id: '3258'
abstract:
- lang: eng
text: CA3 pyramidal neurons are important for memory formation and pattern completion
in the hippocampal network. It is generally thought that proximal synapses from
the mossy fibers activate these neurons most efficiently, whereas distal inputs
from the perforant path have a weaker modulatory influence. We used confocally
targeted patch-clamp recording from dendrites and axons to map the activation
of rat CA3 pyramidal neurons at the subcellular level. Our results reveal two
distinct dendritic domains. In the proximal domain, action potentials initiated
in the axon backpropagate actively with large amplitude and fast time course.
In the distal domain, Na+ channel–mediated dendritic spikes are efficiently initiated
by waveforms mimicking synaptic events. CA3 pyramidal neuron dendrites showed
a high Na+-to-K+ conductance density ratio, providing ideal conditions for active
backpropagation and dendritic spike initiation. Dendritic spikes may enhance the
computational power of CA3 pyramidal neurons in the hippocampal network.
acknowledgement: This work was supported by the Deutsche Forschungsgemeinschaft (TR
3/B10) and the European Union (European Research Council Advanced grant to P.J.).
article_processing_charge: No
article_type: original
author:
- first_name: Sooyun
full_name: Kim, Sooyun
id: 394AB1C8-F248-11E8-B48F-1D18A9856A87
last_name: Kim
- first_name: José
full_name: Guzmán, José
id: 30CC5506-F248-11E8-B48F-1D18A9856A87
last_name: Guzmán
orcid: 0000-0003-2209-5242
- first_name: Hua
full_name: Hu, Hua
id: 4AC0145C-F248-11E8-B48F-1D18A9856A87
last_name: Hu
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Kim S, Guzmán J, Hu H, Jonas PM. Active dendrites support efficient initiation
of dendritic spikes in hippocampal CA3 pyramidal neurons. Nature Neuroscience.
2012;15(4):600-606. doi:10.1038/nn.3060
apa: Kim, S., Guzmán, J., Hu, H., & Jonas, P. M. (2012). Active dendrites support
efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons.
Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.3060
chicago: Kim, Sooyun, José Guzmán, Hua Hu, and Peter M Jonas. “Active Dendrites
Support Efficient Initiation of Dendritic Spikes in Hippocampal CA3 Pyramidal
Neurons.” Nature Neuroscience. Nature Publishing Group, 2012. https://doi.org/10.1038/nn.3060.
ieee: S. Kim, J. Guzmán, H. Hu, and P. M. Jonas, “Active dendrites support efficient
initiation of dendritic spikes in hippocampal CA3 pyramidal neurons,” Nature
Neuroscience, vol. 15, no. 4. Nature Publishing Group, pp. 600–606, 2012.
ista: Kim S, Guzmán J, Hu H, Jonas PM. 2012. Active dendrites support efficient
initiation of dendritic spikes in hippocampal CA3 pyramidal neurons. Nature Neuroscience.
15(4), 600–606.
mla: Kim, Sooyun, et al. “Active Dendrites Support Efficient Initiation of Dendritic
Spikes in Hippocampal CA3 Pyramidal Neurons.” Nature Neuroscience, vol.
15, no. 4, Nature Publishing Group, 2012, pp. 600–06, doi:10.1038/nn.3060.
short: S. Kim, J. Guzmán, H. Hu, P.M. Jonas, Nature Neuroscience 15 (2012) 600–606.
date_created: 2018-12-11T12:02:18Z
date_published: 2012-04-01T00:00:00Z
date_updated: 2023-09-07T11:43:52Z
day: '01'
department:
- _id: PeJo
doi: 10.1038/nn.3060
external_id:
pmid:
- '22388958'
intvolume: ' 15'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617474/
month: '04'
oa: 1
oa_version: Published Version
page: 600 - 606
pmid: 1
project:
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen
publication: Nature Neuroscience
publication_identifier:
issn:
- 1546-1726
publication_status: published
publisher: Nature Publishing Group
publist_id: '3390'
quality_controlled: '1'
related_material:
record:
- id: '2964'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Active dendrites support efficient initiation of dendritic spikes in hippocampal
CA3 pyramidal neurons
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 15
year: '2012'
...