---
_id: '12168'
abstract:
- lang: eng
  text: "Advances in blockchains have influenced the State-Machine-Replication (SMR)
    world and many state-of-the-art blockchain-SMR solutions are based on two pillars:
    Chaining and Leader-rotation. A predetermined round-robin mechanism used for Leader-rotation,
    however, has an undesirable behavior: crashed parties become designated leaders
    infinitely often, slowing down overall system performance. In this paper, we provide
    a new Leader-Aware SMR framework that, among other desirable properties, formalizes
    a Leader-utilization requirement that bounds the number of rounds whose leaders
    are faulty in crash-only executions.\r\nWe introduce Carousel, a novel, reputation-based
    Leader-rotation solution to achieve Leader-Aware SMR. The challenge in adaptive
    Leader-rotation is that it cannot rely on consensus to determine a leader, since
    consensus itself needs a leader. Carousel uses the available on-chain information
    to determine a leader locally and achieves Liveness despite this difficulty. A
    HotStuff implementation fitted with Carousel demonstrates drastic performance
    improvements: it increases throughput over 2x in faultless settings and provided
    a 20x throughput increase and 5x latency reduction in the presence of faults."
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Shir
  full_name: Cohen, Shir
  last_name: Cohen
- first_name: Rati
  full_name: Gelashvili, Rati
  last_name: Gelashvili
- first_name: Eleftherios
  full_name: Kokoris Kogias, Eleftherios
  id: f5983044-d7ef-11ea-ac6d-fd1430a26d30
  last_name: Kokoris Kogias
- first_name: Zekun
  full_name: Li, Zekun
  last_name: Li
- first_name: Dahlia
  full_name: Malkhi, Dahlia
  last_name: Malkhi
- first_name: Alberto
  full_name: Sonnino, Alberto
  last_name: Sonnino
- first_name: Alexander
  full_name: Spiegelman, Alexander
  last_name: Spiegelman
citation:
  ama: 'Cohen S, Gelashvili R, Kokoris Kogias E, et al. Be aware of your leaders.
    In: <i>International Conference on Financial Cryptography and Data Security</i>.
    Vol 13411. Springer Nature; 2022:279-295. doi:<a href="https://doi.org/10.1007/978-3-031-18283-9_13">10.1007/978-3-031-18283-9_13</a>'
  apa: 'Cohen, S., Gelashvili, R., Kokoris Kogias, E., Li, Z., Malkhi, D., Sonnino,
    A., &#38; Spiegelman, A. (2022). Be aware of your leaders. In <i>International
    Conference on Financial Cryptography and Data Security</i> (Vol. 13411, pp. 279–295).
    Grenada: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-18283-9_13">https://doi.org/10.1007/978-3-031-18283-9_13</a>'
  chicago: Cohen, Shir, Rati Gelashvili, Eleftherios Kokoris Kogias, Zekun Li, Dahlia
    Malkhi, Alberto Sonnino, and Alexander Spiegelman. “Be Aware of Your Leaders.”
    In <i>International Conference on Financial Cryptography and Data Security</i>,
    13411:279–95. Springer Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-18283-9_13">https://doi.org/10.1007/978-3-031-18283-9_13</a>.
  ieee: S. Cohen <i>et al.</i>, “Be aware of your leaders,” in <i>International Conference
    on Financial Cryptography and Data Security</i>, Grenada, 2022, vol. 13411, pp.
    279–295.
  ista: 'Cohen S, Gelashvili R, Kokoris Kogias E, Li Z, Malkhi D, Sonnino A, Spiegelman
    A. 2022. Be aware of your leaders. International Conference on Financial Cryptography
    and Data Security. FC: Financial Cryptography and Data Security, LNCS, vol. 13411,
    279–295.'
  mla: Cohen, Shir, et al. “Be Aware of Your Leaders.” <i>International Conference
    on Financial Cryptography and Data Security</i>, vol. 13411, Springer Nature,
    2022, pp. 279–95, doi:<a href="https://doi.org/10.1007/978-3-031-18283-9_13">10.1007/978-3-031-18283-9_13</a>.
  short: S. Cohen, R. Gelashvili, E. Kokoris Kogias, Z. Li, D. Malkhi, A. Sonnino,
    A. Spiegelman, in:, International Conference on Financial Cryptography and Data
    Security, Springer Nature, 2022, pp. 279–295.
conference:
  end_date: 2022-05-06
  location: Grenada
  name: 'FC: Financial Cryptography and Data Security'
  start_date: 2022-05-02
date_created: 2023-01-12T12:10:49Z
date_published: 2022-10-22T00:00:00Z
date_updated: 2023-09-05T15:11:35Z
day: '22'
department:
- _id: ElKo
doi: 10.1007/978-3-031-18283-9_13
external_id:
  arxiv:
  - '2110.00960'
intvolume: '     13411'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2110.00960
month: '10'
oa: 1
oa_version: Preprint
page: 279-295
publication: International Conference on Financial Cryptography and Data Security
publication_identifier:
  eisbn:
  - '9783031182839'
  eissn:
  - 1611-3349
  isbn:
  - '9783031182822'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Be aware of your leaders
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 13411
year: '2022'
...
---
_id: '12170'
abstract:
- lang: eng
  text: We present PET, a specialized and highly optimized framework for partial exploration
    on probabilistic systems. Over the last decade, several significant advances in
    the analysis of Markov decision processes employed partial exploration. In a nutshell,
    this idea allows to focus computation on specific parts of the system, guided
    by heuristics, while maintaining correctness. In particular, only relevant parts
    of the system are constructed on demand, which in turn potentially allows to omit
    constructing large parts of the system. Depending on the model, this leads to
    dramatic speed-ups, in extreme cases even up to an arbitrary factor. PET unifies
    several previous implementations and provides a flexible framework to easily implement
    partial exploration for many further problems. Our experimental evaluation shows
    significant improvements compared to the previous implementations while vastly
    reducing the overhead required to add support for additional properties.
acknowledgement: We thank Pranav Ashok and Maximilian Weininger for their contributions
  to spiritual predecessors of PET as well as motivating the initial development of
  this tool.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Tobias
  full_name: Meggendorfer, Tobias
  id: b21b0c15-30a2-11eb-80dc-f13ca25802e1
  last_name: Meggendorfer
  orcid: 0000-0002-1712-2165
citation:
  ama: 'Meggendorfer T. PET – A partial exploration tool for probabilistic verification.
    In: <i>20th International Symposium on Automated Technology for Verification and
    Analysis</i>. Vol 13505. Springer Nature; 2022:320-326. doi:<a href="https://doi.org/10.1007/978-3-031-19992-9_20">10.1007/978-3-031-19992-9_20</a>'
  apa: 'Meggendorfer, T. (2022). PET – A partial exploration tool for probabilistic
    verification. In <i>20th International Symposium on Automated Technology for Verification
    and Analysis</i> (Vol. 13505, pp. 320–326). Virtual: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-19992-9_20">https://doi.org/10.1007/978-3-031-19992-9_20</a>'
  chicago: Meggendorfer, Tobias. “PET – A Partial Exploration Tool for Probabilistic
    Verification.” In <i>20th International Symposium on Automated Technology for
    Verification and Analysis</i>, 13505:320–26. Springer Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-19992-9_20">https://doi.org/10.1007/978-3-031-19992-9_20</a>.
  ieee: T. Meggendorfer, “PET – A partial exploration tool for probabilistic verification,”
    in <i>20th International Symposium on Automated Technology for Verification and
    Analysis</i>, Virtual, 2022, vol. 13505, pp. 320–326.
  ista: 'Meggendorfer T. 2022. PET – A partial exploration tool for probabilistic
    verification. 20th International Symposium on Automated Technology for Verification
    and Analysis. ATVA: Automated Technology for Verification and Analysis, LNCS,
    vol. 13505, 320–326.'
  mla: Meggendorfer, Tobias. “PET – A Partial Exploration Tool for Probabilistic Verification.”
    <i>20th International Symposium on Automated Technology for Verification and Analysis</i>,
    vol. 13505, Springer Nature, 2022, pp. 320–26, doi:<a href="https://doi.org/10.1007/978-3-031-19992-9_20">10.1007/978-3-031-19992-9_20</a>.
  short: T. Meggendorfer, in:, 20th International Symposium on Automated Technology
    for Verification and Analysis, Springer Nature, 2022, pp. 320–326.
conference:
  end_date: 2022-10-28
  location: Virtual
  name: 'ATVA: Automated Technology for Verification and Analysis'
  start_date: 2022-10-25
date_created: 2023-01-12T12:11:07Z
date_published: 2022-10-21T00:00:00Z
date_updated: 2023-09-05T15:11:51Z
day: '21'
department:
- _id: KrCh
doi: 10.1007/978-3-031-19992-9_20
intvolume: '     13505'
language:
- iso: eng
month: '10'
oa_version: None
page: 320-326
publication: 20th International Symposium on Automated Technology for Verification
  and Analysis
publication_identifier:
  eisbn:
  - '9783031199929'
  eissn:
  - 1611-3349
  isbn:
  - '9783031199912'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: PET – A partial exploration tool for probabilistic verification
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 13505
year: '2022'
...
---
_id: '12171'
abstract:
- lang: eng
  text: 'We propose an algorithmic approach for synthesizing linear hybrid automata
    from time-series data. Unlike existing approaches, our approach provides a whole
    family of models with the same discrete structure but different dynamics. Each
    model in the family is guaranteed to capture the input data up to a precision
    error ε, in the following sense: For each time series, the model contains an execution
    that is ε-close to the data points. Our construction allows to effectively choose
    a model from this family with minimal precision error ε. We demonstrate the algorithm’s
    efficiency and its ability to find precise models in two case studies.'
acknowledgement: This work was supported in part by the European Union’s Horizon 2020
  research and innovation programme under the Marie Skłodowska-Curie grant agreement
  no. 847635, by the ERC-2020-AdG 101020093, by DIREC - Digital Research Centre Denmark,
  and by the Villum Investigator Grant S4OS.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Miriam
  full_name: Garcia Soto, Miriam
  id: 4B3207F6-F248-11E8-B48F-1D18A9856A87
  last_name: Garcia Soto
  orcid: 0000-0003-2936-5719
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Christian
  full_name: Schilling, Christian
  id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
  last_name: Schilling
  orcid: 0000-0003-3658-1065
citation:
  ama: 'Garcia Soto M, Henzinger TA, Schilling C. Synthesis of parametric hybrid automata
    from time series. In: <i>20th International Symposium on Automated Technology
    for Verification and Analysis</i>. Vol 13505. Springer Nature; 2022:337-353. doi:<a
    href="https://doi.org/10.1007/978-3-031-19992-9_22">10.1007/978-3-031-19992-9_22</a>'
  apa: 'Garcia Soto, M., Henzinger, T. A., &#38; Schilling, C. (2022). Synthesis of parametric
    hybrid automata from time series. In <i>20th International Symposium on Automated
    Technology for Verification and Analysis</i> (Vol. 13505, pp. 337–353). Virtual:
    Springer Nature. <a href="https://doi.org/10.1007/978-3-031-19992-9_22">https://doi.org/10.1007/978-3-031-19992-9_22</a>'
  chicago: Garcia Soto, Miriam, Thomas A Henzinger, and Christian Schilling. “Synthesis
    of Parametric Hybrid Automata from Time Series.” In <i>20th International Symposium
    on Automated Technology for Verification and Analysis</i>, 13505:337–53. Springer
    Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-19992-9_22">https://doi.org/10.1007/978-3-031-19992-9_22</a>.
  ieee: M. Garcia Soto, T. A. Henzinger, and C. Schilling, “Synthesis of parametric
    hybrid automata from time series,” in <i>20th International Symposium on Automated
    Technology for Verification and Analysis</i>, Virtual, 2022, vol. 13505, pp. 337–353.
  ista: 'Garcia Soto M, Henzinger TA, Schilling C. 2022. Synthesis of parametric hybrid
    automata from time series. 20th International Symposium on Automated Technology
    for Verification and Analysis. ATVA: Automated Technology for Verification and
    Analysis, LNCS, vol. 13505, 337–353.'
  mla: Garcia Soto, Miriam, et al. “Synthesis of Parametric Hybrid Automata from Time
    Series.” <i>20th International Symposium on Automated Technology for Verification
    and Analysis</i>, vol. 13505, Springer Nature, 2022, pp. 337–53, doi:<a href="https://doi.org/10.1007/978-3-031-19992-9_22">10.1007/978-3-031-19992-9_22</a>.
  short: M. Garcia Soto, T.A. Henzinger, C. Schilling, in:, 20th International Symposium
    on Automated Technology for Verification and Analysis, Springer Nature, 2022,
    pp. 337–353.
conference:
  end_date: 2022-10-28
  location: Virtual
  name: 'ATVA: Automated Technology for Verification and Analysis'
  start_date: 2022-10-25
date_created: 2023-01-12T12:11:16Z
date_published: 2022-10-21T00:00:00Z
date_updated: 2023-02-13T09:27:55Z
day: '21'
department:
- _id: ToHe
doi: 10.1007/978-3-031-19992-9_22
ec_funded: 1
external_id:
  arxiv:
  - '2208.06383'
intvolume: '     13505'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2208.06383
month: '10'
oa: 1
oa_version: Preprint
page: 337-353
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 20th International Symposium on Automated Technology for Verification
  and Analysis
publication_identifier:
  eisbn:
  - '9783031199929'
  eissn:
  - 1611-3349
  isbn:
  - '9783031199912'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synthesis of parametric hybrid automata from time series
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13505
year: '2022'
...
---
_id: '12173'
abstract:
- lang: eng
  text: With increasing urbanization and industrialization, the prevalence of inflammatory
    bowel diseases (IBDs) has steadily been rising over the past two decades. IBD
    involves flares of gastrointestinal (GI) inflammation accompanied by microbiota
    perturbations. However, microbial mechanisms that trigger such flares remain elusive.
    Here, we analyzed the association of the emerging pathogen atypical enteropathogenic
    E. coli (aEPEC) with IBD disease activity. The presence of diarrheagenic E. coli
    was assessed in stool samples from 630 IBD patients and 234 age- and sex-matched
    controls without GI symptoms. Microbiota was analyzed with 16S ribosomal RNA gene
    amplicon sequencing, and 57 clinical aEPEC isolates were subjected to whole-genome
    sequencing and in vitro pathogenicity experiments including biofilm formation,
    epithelial barrier function and the ability to induce pro-inflammatory signaling.
    The presence of aEPEC correlated with laboratory, clinical and endoscopic disease
    activity in ulcerative colitis (UC), as well as microbiota dysbiosis. In vitro,
    aEPEC strains induce epithelial p21-activated kinases, disrupt the epithelial
    barrier and display potent biofilm formation. The effector proteins espV and espG2
    distinguish aEPEC cultured from UC and Crohn’s disease patients, respectively.
    EspV-positive aEPEC harbor more virulence factors and have a higher pro-inflammatory
    potential, which is counteracted by 5-ASA. aEPEC may tip a fragile immune–microbiota
    homeostasis and thereby contribute to flares in UC. aEPEC isolates from UC patients
    display properties to disrupt the epithelial barrier and to induce pro-inflammatory
    signaling in vitro.
acknowledgement: "We would like to acknowledge Anita Krnjic, Christina Gmainer, Marion
  Nehr, Helga Mock, and Sena Ecin for technical support in conducting the experiments.\r\nThis
  study was supported by the Austrian Science Fund (P 32302) and the Vienna Science
  and Technology Fund (LS18- 053; Austrian Science Fund (FWF)) [P 32302]."
article_number: e2143218
article_processing_charge: No
article_type: original
author:
- first_name: Maximilian
  full_name: Baumgartner, Maximilian
  last_name: Baumgartner
- first_name: Rebecca
  full_name: Zirnbauer, Rebecca
  last_name: Zirnbauer
- first_name: Sabine
  full_name: Schlager, Sabine
  last_name: Schlager
- first_name: Daniel
  full_name: Mertens, Daniel
  last_name: Mertens
- first_name: Nikolaus
  full_name: Gasche, Nikolaus
  last_name: Gasche
- first_name: Barbara
  full_name: Sladek, Barbara
  last_name: Sladek
- first_name: Craig
  full_name: Herbold, Craig
  last_name: Herbold
- first_name: Olga
  full_name: Bochkareva, Olga
  last_name: Bochkareva
- first_name: Vera
  full_name: Emelianenko, Vera
  id: 20152b9d-927a-11ed-8107-be36d740812d
  last_name: Emelianenko
- first_name: Harald
  full_name: Vogelsang, Harald
  last_name: Vogelsang
- first_name: Michaela
  full_name: Lang, Michaela
  last_name: Lang
- first_name: Anton
  full_name: Klotz, Anton
  last_name: Klotz
- first_name: Birgit
  full_name: Moik, Birgit
  last_name: Moik
- first_name: Athanasios
  full_name: Makristathis, Athanasios
  last_name: Makristathis
- first_name: David
  full_name: Berry, David
  last_name: Berry
- first_name: Stefanie
  full_name: Dabsch, Stefanie
  last_name: Dabsch
- first_name: Vineeta
  full_name: Khare, Vineeta
  last_name: Khare
- first_name: Christoph
  full_name: Gasche, Christoph
  last_name: Gasche
citation:
  ama: Baumgartner M, Zirnbauer R, Schlager S, et al. Atypical enteropathogenic E.
    coli are associated with disease activity in ulcerative colitis. <i>Gut Microbes</i>.
    2022;14(1). doi:<a href="https://doi.org/10.1080/19490976.2022.2143218">10.1080/19490976.2022.2143218</a>
  apa: Baumgartner, M., Zirnbauer, R., Schlager, S., Mertens, D., Gasche, N., Sladek,
    B., … Gasche, C. (2022). Atypical enteropathogenic E. coli are associated with
    disease activity in ulcerative colitis. <i>Gut Microbes</i>. Taylor &#38; Francis.
    <a href="https://doi.org/10.1080/19490976.2022.2143218">https://doi.org/10.1080/19490976.2022.2143218</a>
  chicago: Baumgartner, Maximilian, Rebecca Zirnbauer, Sabine Schlager, Daniel Mertens,
    Nikolaus Gasche, Barbara Sladek, Craig Herbold, et al. “Atypical Enteropathogenic
    E. Coli Are Associated with Disease Activity in Ulcerative Colitis.” <i>Gut Microbes</i>.
    Taylor &#38; Francis, 2022. <a href="https://doi.org/10.1080/19490976.2022.2143218">https://doi.org/10.1080/19490976.2022.2143218</a>.
  ieee: M. Baumgartner <i>et al.</i>, “Atypical enteropathogenic E. coli are associated
    with disease activity in ulcerative colitis,” <i>Gut Microbes</i>, vol. 14, no.
    1. Taylor &#38; Francis, 2022.
  ista: Baumgartner M, Zirnbauer R, Schlager S, Mertens D, Gasche N, Sladek B, Herbold
    C, Bochkareva O, Emelianenko V, Vogelsang H, Lang M, Klotz A, Moik B, Makristathis
    A, Berry D, Dabsch S, Khare V, Gasche C. 2022. Atypical enteropathogenic E. coli
    are associated with disease activity in ulcerative colitis. Gut Microbes. 14(1),
    e2143218.
  mla: Baumgartner, Maximilian, et al. “Atypical Enteropathogenic E. Coli Are Associated
    with Disease Activity in Ulcerative Colitis.” <i>Gut Microbes</i>, vol. 14, no.
    1, e2143218, Taylor &#38; Francis, 2022, doi:<a href="https://doi.org/10.1080/19490976.2022.2143218">10.1080/19490976.2022.2143218</a>.
  short: M. Baumgartner, R. Zirnbauer, S. Schlager, D. Mertens, N. Gasche, B. Sladek,
    C. Herbold, O. Bochkareva, V. Emelianenko, H. Vogelsang, M. Lang, A. Klotz, B.
    Moik, A. Makristathis, D. Berry, S. Dabsch, V. Khare, C. Gasche, Gut Microbes
    14 (2022).
date_created: 2023-01-12T12:11:36Z
date_published: 2022-11-22T00:00:00Z
date_updated: 2023-08-04T09:10:18Z
day: '22'
ddc:
- '570'
department:
- _id: FyKo
doi: 10.1080/19490976.2022.2143218
external_id:
  isi:
  - '000889180100001'
file:
- access_level: open_access
  checksum: ee7681a17ae27645e9b5c1df61c15429
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-26T10:56:51Z
  date_updated: 2023-01-26T10:56:51Z
  file_id: '12400'
  file_name: 2022_GutMicrobes_Baumgartner.pdf
  file_size: 4075251
  relation: main_file
  success: 1
file_date_updated: 2023-01-26T10:56:51Z
has_accepted_license: '1'
intvolume: '        14'
isi: 1
issue: '1'
keyword:
- Infectious Diseases
- Microbiology (medical)
- Gastroenterology
- Microbiology
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Gut Microbes
publication_identifier:
  eissn:
  - 1949-0984
  issn:
  - 1949-0976
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
scopus_import: '1'
status: public
title: Atypical enteropathogenic E. coli are associated with disease activity in ulcerative
  colitis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 14
year: '2022'
...
---
_id: '12174'
abstract:
- lang: eng
  text: "Vacuolar-type H+-ATPase (V-ATPase) is a multimeric complex present in a variety
    of cellular membranes that acts as an ATP-dependent proton pump and plays a key
    role in pH homeostasis and intracellular signalling pathways. In humans, 22 autosomal
    genes encode for a redundant set of subunits allowing the composition of diverse
    V-ATPase complexes with specific properties and expression. Sixteen subunits have
    been linked to human disease.\r\nHere we describe 26 patients harbouring 20 distinct
    pathogenic de novo missense ATP6V1A variants, mainly clustering within the ATP
    synthase α/β family-nucleotide-binding domain. At a mean age of 7 years (extremes:
    6 weeks, youngest deceased patient to 22 years, oldest patient) clinical pictures
    included early lethal encephalopathies with rapidly progressive massive brain
    atrophy, severe developmental epileptic encephalopathies and static intellectual
    disability with epilepsy. The first clinical manifestation was early hypotonia,
    in 70%; 81% developed epilepsy, manifested as developmental epileptic encephalopathies
    in 58% of the cohort and with infantile spasms in 62%; 63% of developmental epileptic
    encephalopathies failed to achieve any developmental, communicative or motor skills.
    Less severe outcomes were observed in 23% of patients who, at a mean age of 10
    years and 6 months, exhibited moderate intellectual disability, with independent
    walking and variable epilepsy. None of the patients developed communicative language.
    Microcephaly (38%) and amelogenesis imperfecta/enamel dysplasia (42%) were additional
    clinical features. Brain MRI demonstrated hypomyelination and generalized atrophy
    in 68%. Atrophy was progressive in all eight individuals undergoing repeated MRIs.</jats:p>\r\n
    \              <jats:p>Fibroblasts of two patients with developmental epileptic
    encephalopathies showed decreased LAMP1 expression, Lysotracker staining and increased
    organelle pH, consistent with lysosomal impairment and loss of V-ATPase function.
    Fibroblasts of two patients with milder disease, exhibited a different phenotype
    with increased Lysotracker staining, decreased organelle pH and no significant
    modification in LAMP1 expression. Quantification of substrates for lysosomal enzymes
    in cellular extracts from four patients revealed discrete accumulation. Transmission
    electron microscopy of fibroblasts of four patients with variable severity and
    of induced pluripotent stem cell-derived neurons from two patients with developmental
    epileptic encephalopathies showed electron-dense inclusions, lipid droplets, osmiophilic
    material and lamellated membrane structures resembling phospholipids. Quantitative
    assessment in induced pluripotent stem cell-derived neurons identified significantly
    smaller lysosomes.\r\nATP6V1A-related encephalopathy represents a new paradigm
    among lysosomal disorders. It results from a dysfunctional endo-lysosomal membrane
    protein causing altered pH homeostasis. Its pathophysiology implies intracellular
    accumulation of substrates whose composition remains unclear, and a combination
    of developmental brain abnormalities and neurodegenerative changes established
    during prenatal and early postanal development, whose severity is variably determined
    by specific pathogenic variants."
acknowledged_ssus:
- _id: EM-Fac
- _id: LifeSc
acknowledgement: "We thank all patients and family members for their participation
  in this study. We thank Melanie Pieraks and Eva Reinthaler (Neurolentech, Austria)
  for generating the human iPSC lines and\r\nfor performing quality checks. We thank
  Vanessa Zheden and Daniel Gütl for their excellent technical support in the specimen
  preparation for transmission electron microscopy and Flavia Leite for preparing
  the lentiviruses. The support from Electron Microscopy Facility and Molecular Biology
  Services at IST Austria is greatly acknowledged. We would like to thank Doctors
  Jane Hurst and Richard Scott for their help in retrieving the detailed clinical
  information of Patient 17. The research team acknowledges the support of the National
  Institute for Health Research, through the Comprehensive Clinical Research Network.
  See Supplementary Material for Undiagnosed Disease Network consortium details. Genetic
  information on Patient 23 was made available through access to the data and findings
  generated by the 100 000 Genomes\r\nProject; www.genomicsengland.co.uk (to K.L.).
  \r\nThis work was supported by the EU 7th Framework Programme (FP7) under the project
  DESIRE grant N602531 (to R.G.); the Regione Toscana under the Call for Health 2018
  (grant\r\nDECODE-EE) (to R.G.); the ‘Brain Project’ by Fondazione Cassa di Risparmio
  di Firenze (to R.G.); IRCCS Ospedale Policlinico San Martino 5×1000 and Ricerca
  Corrente (to A.F. and F.B.). The European Reference Network (ERN) for rare and complex
  epilepsies (EpiCARE) provided financial support for meetings organization. The DDD
  study presents independent research commissioned by the Health Innovation Challenge
  Fund (grant number HICF-1009-003), a parallel funding partnership between Wellcome
  and the Department of Health, and the Wellcome Sanger Institute (grant number WT098051).
  The views expressed in this publication\r\nare those of the author(s) and not necessarily
  those of Wellcome or the Department of Health. The study has UK Research Ethics
  Committee approval (10/H0305/83, granted by the Cambridge South REC, and GEN/284/12
  granted by the Republic of Ireland REC). This study makes use of DECIPHER (https://www.deciphergenomics.org),
  which is funded by Wellcome. K.K.-S. was supported by the ISTplus fellowship. "
article_processing_charge: No
article_type: original
author:
- first_name: Renzo
  full_name: Guerrini, Renzo
  last_name: Guerrini
- first_name: Davide
  full_name: Mei, Davide
  last_name: Mei
- first_name: Margit Katalin
  full_name: Szigeti, Margit Katalin
  id: 44F4BDC0-F248-11E8-B48F-1D18A9856A87
  last_name: Szigeti
  orcid: 0000-0001-9500-8758
- first_name: Sara
  full_name: Pepe, Sara
  last_name: Pepe
- first_name: Mary Kay
  full_name: Koenig, Mary Kay
  last_name: Koenig
- first_name: Gretchen
  full_name: Von Allmen, Gretchen
  last_name: Von Allmen
- first_name: Megan T
  full_name: Cho, Megan T
  last_name: Cho
- first_name: Kimberly
  full_name: McDonald, Kimberly
  last_name: McDonald
- first_name: Janice
  full_name: Baker, Janice
  last_name: Baker
- first_name: Vikas
  full_name: Bhambhani, Vikas
  last_name: Bhambhani
- first_name: Zöe
  full_name: Powis, Zöe
  last_name: Powis
- first_name: Lance
  full_name: Rodan, Lance
  last_name: Rodan
- first_name: Rima
  full_name: Nabbout, Rima
  last_name: Nabbout
- first_name: Giulia
  full_name: Barcia, Giulia
  last_name: Barcia
- first_name: Jill A
  full_name: Rosenfeld, Jill A
  last_name: Rosenfeld
- first_name: Carlos A
  full_name: Bacino, Carlos A
  last_name: Bacino
- first_name: Cyril
  full_name: Mignot, Cyril
  last_name: Mignot
- first_name: Lillian H
  full_name: Power, Lillian H
  last_name: Power
- first_name: Catharine J
  full_name: Harris, Catharine J
  last_name: Harris
- first_name: Dragan
  full_name: Marjanovic, Dragan
  last_name: Marjanovic
- first_name: Rikke S
  full_name: Møller, Rikke S
  last_name: Møller
- first_name: Trine B
  full_name: Hammer, Trine B
  last_name: Hammer
- first_name: Riikka
  full_name: Keski Filppula, Riikka
  last_name: Keski Filppula
- first_name: Päivi
  full_name: Vieira, Päivi
  last_name: Vieira
- first_name: Clara
  full_name: Hildebrandt, Clara
  last_name: Hildebrandt
- first_name: Stephanie
  full_name: Sacharow, Stephanie
  last_name: Sacharow
- first_name: Luca
  full_name: Maragliano, Luca
  last_name: Maragliano
- first_name: Fabio
  full_name: Benfenati, Fabio
  last_name: Benfenati
- first_name: Katherine
  full_name: Lachlan, Katherine
  last_name: Lachlan
- first_name: Andreas
  full_name: Benneche, Andreas
  last_name: Benneche
- first_name: Florence
  full_name: Petit, Florence
  last_name: Petit
- first_name: Jean Madeleine
  full_name: de Sainte Agathe, Jean Madeleine
  last_name: de Sainte Agathe
- first_name: Barbara
  full_name: Hallinan, Barbara
  last_name: Hallinan
- first_name: Yue
  full_name: Si, Yue
  last_name: Si
- first_name: Ingrid M
  full_name: Wentzensen, Ingrid M
  last_name: Wentzensen
- first_name: Fanggeng
  full_name: Zou, Fanggeng
  last_name: Zou
- first_name: Vinodh
  full_name: Narayanan, Vinodh
  last_name: Narayanan
- first_name: Naomichi
  full_name: Matsumoto, Naomichi
  last_name: Matsumoto
- first_name: Alessandra
  full_name: Boncristiano, Alessandra
  last_name: Boncristiano
- first_name: Giancarlo
  full_name: la Marca, Giancarlo
  last_name: la Marca
- first_name: Mitsuhiro
  full_name: Kato, Mitsuhiro
  last_name: Kato
- first_name: Kristin
  full_name: Anderson, Kristin
  last_name: Anderson
- first_name: Carmen
  full_name: Barba, Carmen
  last_name: Barba
- first_name: Luisa
  full_name: Sturiale, Luisa
  last_name: Sturiale
- first_name: Domenico
  full_name: Garozzo, Domenico
  last_name: Garozzo
- first_name: Roberto
  full_name: Bei, Roberto
  last_name: Bei
- first_name: Laura
  full_name: Masuelli, Laura
  last_name: Masuelli
- first_name: Valerio
  full_name: Conti, Valerio
  last_name: Conti
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
- first_name: Anna
  full_name: Fassio, Anna
  last_name: Fassio
citation:
  ama: 'Guerrini R, Mei D, Szigeti MK, et al. Phenotypic and genetic spectrum of ATP6V1A
    encephalopathy: A disorder of lysosomal homeostasis. <i>Brain</i>. 2022;145(8):2687-2703.
    doi:<a href="https://doi.org/10.1093/brain/awac145">10.1093/brain/awac145</a>'
  apa: 'Guerrini, R., Mei, D., Szigeti, M. K., Pepe, S., Koenig, M. K., Von Allmen,
    G., … Fassio, A. (2022). Phenotypic and genetic spectrum of ATP6V1A encephalopathy:
    A disorder of lysosomal homeostasis. <i>Brain</i>. Oxford University Press. <a
    href="https://doi.org/10.1093/brain/awac145">https://doi.org/10.1093/brain/awac145</a>'
  chicago: 'Guerrini, Renzo, Davide Mei, Margit Katalin Szigeti, Sara Pepe, Mary Kay
    Koenig, Gretchen Von Allmen, Megan T Cho, et al. “Phenotypic and Genetic Spectrum
    of ATP6V1A Encephalopathy: A Disorder of Lysosomal Homeostasis.” <i>Brain</i>.
    Oxford University Press, 2022. <a href="https://doi.org/10.1093/brain/awac145">https://doi.org/10.1093/brain/awac145</a>.'
  ieee: 'R. Guerrini <i>et al.</i>, “Phenotypic and genetic spectrum of ATP6V1A encephalopathy:
    A disorder of lysosomal homeostasis,” <i>Brain</i>, vol. 145, no. 8. Oxford University
    Press, pp. 2687–2703, 2022.'
  ista: 'Guerrini R, Mei D, Szigeti MK, Pepe S, Koenig MK, Von Allmen G, Cho MT, McDonald
    K, Baker J, Bhambhani V, Powis Z, Rodan L, Nabbout R, Barcia G, Rosenfeld JA,
    Bacino CA, Mignot C, Power LH, Harris CJ, Marjanovic D, Møller RS, Hammer TB,
    Keski Filppula R, Vieira P, Hildebrandt C, Sacharow S, Maragliano L, Benfenati
    F, Lachlan K, Benneche A, Petit F, de Sainte Agathe JM, Hallinan B, Si Y, Wentzensen
    IM, Zou F, Narayanan V, Matsumoto N, Boncristiano A, la Marca G, Kato M, Anderson
    K, Barba C, Sturiale L, Garozzo D, Bei R, Masuelli L, Conti V, Novarino G, Fassio
    A. 2022. Phenotypic and genetic spectrum of ATP6V1A encephalopathy: A disorder
    of lysosomal homeostasis. Brain. 145(8), 2687–2703.'
  mla: 'Guerrini, Renzo, et al. “Phenotypic and Genetic Spectrum of ATP6V1A Encephalopathy:
    A Disorder of Lysosomal Homeostasis.” <i>Brain</i>, vol. 145, no. 8, Oxford University
    Press, 2022, pp. 2687–703, doi:<a href="https://doi.org/10.1093/brain/awac145">10.1093/brain/awac145</a>.'
  short: R. Guerrini, D. Mei, M.K. Szigeti, S. Pepe, M.K. Koenig, G. Von Allmen, M.T.
    Cho, K. McDonald, J. Baker, V. Bhambhani, Z. Powis, L. Rodan, R. Nabbout, G. Barcia,
    J.A. Rosenfeld, C.A. Bacino, C. Mignot, L.H. Power, C.J. Harris, D. Marjanovic,
    R.S. Møller, T.B. Hammer, R. Keski Filppula, P. Vieira, C. Hildebrandt, S. Sacharow,
    L. Maragliano, F. Benfenati, K. Lachlan, A. Benneche, F. Petit, J.M. de Sainte
    Agathe, B. Hallinan, Y. Si, I.M. Wentzensen, F. Zou, V. Narayanan, N. Matsumoto,
    A. Boncristiano, G. la Marca, M. Kato, K. Anderson, C. Barba, L. Sturiale, D.
    Garozzo, R. Bei, L. Masuelli, V. Conti, G. Novarino, A. Fassio, Brain 145 (2022)
    2687–2703.
date_created: 2023-01-12T12:11:45Z
date_published: 2022-08-01T00:00:00Z
date_updated: 2023-08-04T09:13:08Z
day: '01'
department:
- _id: GaNo
doi: 10.1093/brain/awac145
ec_funded: 1
external_id:
  isi:
  - '000807770000001'
intvolume: '       145'
isi: 1
issue: '8'
keyword:
- Neurology (clinical)
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/brain/awac145
month: '08'
oa: 1
oa_version: Published Version
page: 2687-2703
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Brain
publication_identifier:
  eissn:
  - 1460-2156
  issn:
  - 0006-8950
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Phenotypic and genetic spectrum of ATP6V1A encephalopathy: A disorder of lysosomal
  homeostasis'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 145
year: '2022'
...
---
_id: '12175'
abstract:
- lang: eng
  text: An automaton is history-deterministic (HD) if one can safely resolve its non-deterministic
    choices on the fly. In a recent paper, Henzinger, Lehtinen and Totzke studied
    this in the context of Timed Automata [9], where it was conjectured that the class
    of timed ω-languages recognised by HD-timed automata strictly extends that of
    deterministic ones. We provide a proof for this fact.
acknowledgement: This work was supported in part by the ERC-2020-AdG 101020093, the
  EPSRC project EP/V025848/1, and the EPSRC project EP/X017796/1.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Sougata
  full_name: Bose, Sougata
  last_name: Bose
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Karoliina
  full_name: Lehtinen, Karoliina
  last_name: Lehtinen
- first_name: Sven
  full_name: Schewe, Sven
  last_name: Schewe
- first_name: Patrick
  full_name: Totzke, Patrick
  last_name: Totzke
citation:
  ama: 'Bose S, Henzinger TA, Lehtinen K, Schewe S, Totzke P. History-deterministic
    timed automata are not determinizable. In: <i>16th International Conference on
    Reachability Problems</i>. Vol 13608. Springer Nature; 2022:67-76. doi:<a href="https://doi.org/10.1007/978-3-031-19135-0_5">10.1007/978-3-031-19135-0_5</a>'
  apa: 'Bose, S., Henzinger, T. A., Lehtinen, K., Schewe, S., &#38; Totzke, P. (2022).
    History-deterministic timed automata are not determinizable. In <i>16th International
    Conference on Reachability Problems</i> (Vol. 13608, pp. 67–76). Kaiserslautern,
    Germany: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-19135-0_5">https://doi.org/10.1007/978-3-031-19135-0_5</a>'
  chicago: Bose, Sougata, Thomas A Henzinger, Karoliina Lehtinen, Sven Schewe, and
    Patrick Totzke. “History-Deterministic Timed Automata Are Not Determinizable.”
    In <i>16th International Conference on Reachability Problems</i>, 13608:67–76.
    Springer Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-19135-0_5">https://doi.org/10.1007/978-3-031-19135-0_5</a>.
  ieee: S. Bose, T. A. Henzinger, K. Lehtinen, S. Schewe, and P. Totzke, “History-deterministic
    timed automata are not determinizable,” in <i>16th International Conference on
    Reachability Problems</i>, Kaiserslautern, Germany, 2022, vol. 13608, pp. 67–76.
  ista: 'Bose S, Henzinger TA, Lehtinen K, Schewe S, Totzke P. 2022. History-deterministic
    timed automata are not determinizable. 16th International Conference on Reachability
    Problems. RC: Reachability Problems, LNCS, vol. 13608, 67–76.'
  mla: Bose, Sougata, et al. “History-Deterministic Timed Automata Are Not Determinizable.”
    <i>16th International Conference on Reachability Problems</i>, vol. 13608, Springer
    Nature, 2022, pp. 67–76, doi:<a href="https://doi.org/10.1007/978-3-031-19135-0_5">10.1007/978-3-031-19135-0_5</a>.
  short: S. Bose, T.A. Henzinger, K. Lehtinen, S. Schewe, P. Totzke, in:, 16th International
    Conference on Reachability Problems, Springer Nature, 2022, pp. 67–76.
conference:
  end_date: 2022-10-21
  location: Kaiserslautern, Germany
  name: 'RC: Reachability Problems'
  start_date: 2022-10-17
date_created: 2023-01-12T12:11:57Z
date_published: 2022-10-12T00:00:00Z
date_updated: 2023-09-05T15:12:08Z
day: '12'
department:
- _id: ToHe
doi: 10.1007/978-3-031-19135-0_5
ec_funded: 1
intvolume: '     13608'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://hal.science/hal-03849398/
month: '10'
oa: 1
oa_version: Preprint
page: 67-76
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 16th International Conference on Reachability Problems
publication_identifier:
  eisbn:
  - '9783031191350'
  eissn:
  - 1611-3349
  isbn:
  - '9783031191343'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: History-deterministic timed automata are not determinizable
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 13608
year: '2022'
...
---
_id: '12176'
abstract:
- lang: eng
  text: "A proof of exponentiation (PoE) in a group G of unknown order allows a prover
    to convince a verifier that a tuple (x,q,T,y)∈G×N×N×G satisfies xqT=y. This primitive
    has recently found exciting applications in the constructions of verifiable delay
    functions and succinct arguments of knowledge. The most practical PoEs only achieve
    soundness either under computational assumptions, i.e., they are arguments (Wesolowski,
    Journal of Cryptology 2020), or in groups that come with the promise of not having
    any small subgroups (Pietrzak, ITCS 2019). The only statistically-sound PoE in
    general groups of unknown order is due to Block et al. (CRYPTO 2021), and can
    be seen as an elaborate parallel repetition of Pietrzak’s PoE: to achieve λ bits
    of security, say λ=80, the number of repetitions required (and thus the blow-up
    in communication) is as large as λ.\r\n\r\nIn this work, we propose a statistically-sound
    PoE for the case where the exponent q is the product of all primes up to some
    bound B. We show that, in this case, it suffices to run only λ/log(B) parallel
    instances of Pietrzak’s PoE, which reduces the concrete proof-size compared to
    Block et al. by an order of magnitude. Furthermore, we show that in the known
    applications where PoEs are used as a building block such structured exponents
    are viable. Finally, we also discuss batching of our PoE, showing that many proofs
    (for the same G and q but different x and T) can be batched by adding only a single
    element to the proof per additional statement."
acknowledgement: "We would like to thank the authors of [BHR+21] for clarifying several
  questions we had\r\nregarding their results. Pavel Hubá£ek was supported by the
  Grant Agency of the Czech\r\nRepublic under the grant agreement no. 19-27871X and
  by the Charles University project\r\nUNCE/SCI/004. Chethan Kamath is supported by
  Azrieli International Postdoctoral Fellowship\r\nand ISF grants 484/18 and 1789/19.
  Karen Klein was supported in part by ERC CoG grant\r\n724307 and conducted part
  of this work at Institute of Science and Technology Austria."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Charlotte
  full_name: Hoffmann, Charlotte
  id: 0f78d746-dc7d-11ea-9b2f-83f92091afe7
  last_name: Hoffmann
  orcid: 0000-0003-2027-5549
- first_name: Pavel
  full_name: Hubáček, Pavel
  last_name: Hubáček
- first_name: Chethan
  full_name: Kamath, Chethan
  last_name: Kamath
- first_name: Karen
  full_name: Klein, Karen
  last_name: Klein
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Hoffmann C, Hubáček P, Kamath C, Klein K, Pietrzak KZ. Practical statistically-sound
    proofs of exponentiation in any group. In: <i>Advances in Cryptology – CRYPTO
    2022</i>. Vol 13508. Springer Nature; 2022:370-399. doi:<a href="https://doi.org/10.1007/978-3-031-15979-4_13">10.1007/978-3-031-15979-4_13</a>'
  apa: 'Hoffmann, C., Hubáček, P., Kamath, C., Klein, K., &#38; Pietrzak, K. Z. (2022).
    Practical statistically-sound proofs of exponentiation in any group. In <i>Advances
    in Cryptology – CRYPTO 2022</i> (Vol. 13508, pp. 370–399). Santa Barbara, CA,
    United States: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-15979-4_13">https://doi.org/10.1007/978-3-031-15979-4_13</a>'
  chicago: Hoffmann, Charlotte, Pavel Hubáček, Chethan Kamath, Karen Klein, and Krzysztof
    Z Pietrzak. “Practical Statistically-Sound Proofs of Exponentiation in Any Group.”
    In <i>Advances in Cryptology – CRYPTO 2022</i>, 13508:370–99. Springer Nature,
    2022. <a href="https://doi.org/10.1007/978-3-031-15979-4_13">https://doi.org/10.1007/978-3-031-15979-4_13</a>.
  ieee: C. Hoffmann, P. Hubáček, C. Kamath, K. Klein, and K. Z. Pietrzak, “Practical
    statistically-sound proofs of exponentiation in any group,” in <i>Advances in
    Cryptology – CRYPTO 2022</i>, Santa Barbara, CA, United States, 2022, vol. 13508,
    pp. 370–399.
  ista: 'Hoffmann C, Hubáček P, Kamath C, Klein K, Pietrzak KZ. 2022. Practical statistically-sound
    proofs of exponentiation in any group. Advances in Cryptology – CRYPTO 2022. CRYYPTO:
    International Cryptology Conference, LNCS, vol. 13508, 370–399.'
  mla: Hoffmann, Charlotte, et al. “Practical Statistically-Sound Proofs of Exponentiation
    in Any Group.” <i>Advances in Cryptology – CRYPTO 2022</i>, vol. 13508, Springer
    Nature, 2022, pp. 370–99, doi:<a href="https://doi.org/10.1007/978-3-031-15979-4_13">10.1007/978-3-031-15979-4_13</a>.
  short: C. Hoffmann, P. Hubáček, C. Kamath, K. Klein, K.Z. Pietrzak, in:, Advances
    in Cryptology – CRYPTO 2022, Springer Nature, 2022, pp. 370–399.
conference:
  end_date: 2022-08-18
  location: Santa Barbara, CA, United States
  name: 'CRYYPTO: International Cryptology Conference'
  start_date: 2022-08-15
date_created: 2023-01-12T12:12:07Z
date_published: 2022-10-13T00:00:00Z
date_updated: 2023-09-05T15:12:27Z
day: '13'
department:
- _id: KrPi
doi: 10.1007/978-3-031-15979-4_13
external_id:
  isi:
  - '000886792700013'
intvolume: '     13508'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2022/1021
month: '10'
oa: 1
oa_version: Preprint
page: 370-399
publication: Advances in Cryptology – CRYPTO 2022
publication_identifier:
  eisbn:
  - '9783031159794'
  eissn:
  - 1611-3349
  isbn:
  - '9783031159787'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Practical statistically-sound proofs of exponentiation in any group
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 13508
year: '2022'
...
---
_id: '12177'
abstract:
- lang: eng
  text: Using elementary hyperbolic geometry, we give an explicit formula for the
    contraction constant of the skinning map over moduli spaces of relatively acylindrical
    hyperbolic manifolds.
acknowledgement: "The first author was partially supported by the National Science
  Foundation under Grant\r\nNo. DMS-1928930 while participating in a program hosted
  by the Mathematical Sciences Research Institute in Berkeley, California, during
  the Fall 2020 semester. The second author gratefully acknowledges funding by the
  Austrian Science Fund (FWF) through grants F65 and ESPRIT 208, by the European Research
  Council (ERC, grant No. 716117, awarded to Prof. Dr. Jan Maas), and by the Deutsche
  Forschungsgemeinschaft through the SPP 2265."
article_processing_charge: No
article_type: original
author:
- first_name: Tommaso
  full_name: Cremaschi, Tommaso
  last_name: Cremaschi
- first_name: Lorenzo
  full_name: Dello Schiavo, Lorenzo
  id: ECEBF480-9E4F-11EA-B557-B0823DDC885E
  last_name: Dello Schiavo
  orcid: 0000-0002-9881-6870
citation:
  ama: Cremaschi T, Dello Schiavo L. Effective contraction of Skinning maps. <i>Proceedings
    of the American Mathematical Society, Series B</i>. 2022;9(43):445-459. doi:<a
    href="https://doi.org/10.1090/bproc/134">10.1090/bproc/134</a>
  apa: Cremaschi, T., &#38; Dello Schiavo, L. (2022). Effective contraction of Skinning
    maps. <i>Proceedings of the American Mathematical Society, Series B</i>. American
    Mathematical Society. <a href="https://doi.org/10.1090/bproc/134">https://doi.org/10.1090/bproc/134</a>
  chicago: Cremaschi, Tommaso, and Lorenzo Dello Schiavo. “Effective Contraction of
    Skinning Maps.” <i>Proceedings of the American Mathematical Society, Series B</i>.
    American Mathematical Society, 2022. <a href="https://doi.org/10.1090/bproc/134">https://doi.org/10.1090/bproc/134</a>.
  ieee: T. Cremaschi and L. Dello Schiavo, “Effective contraction of Skinning maps,”
    <i>Proceedings of the American Mathematical Society, Series B</i>, vol. 9, no.
    43. American Mathematical Society, pp. 445–459, 2022.
  ista: Cremaschi T, Dello Schiavo L. 2022. Effective contraction of Skinning maps.
    Proceedings of the American Mathematical Society, Series B. 9(43), 445–459.
  mla: Cremaschi, Tommaso, and Lorenzo Dello Schiavo. “Effective Contraction of Skinning
    Maps.” <i>Proceedings of the American Mathematical Society, Series B</i>, vol.
    9, no. 43, American Mathematical Society, 2022, pp. 445–59, doi:<a href="https://doi.org/10.1090/bproc/134">10.1090/bproc/134</a>.
  short: T. Cremaschi, L. Dello Schiavo, Proceedings of the American Mathematical
    Society, Series B 9 (2022) 445–459.
date_created: 2023-01-12T12:12:17Z
date_published: 2022-11-02T00:00:00Z
date_updated: 2023-01-26T13:04:13Z
day: '02'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1090/bproc/134
ec_funded: 1
file:
- access_level: open_access
  checksum: cb4a79937c1f60d4c329a10ee797f0d2
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-26T13:02:07Z
  date_updated: 2023-01-26T13:02:07Z
  file_id: '12404'
  file_name: 2022_ProceedingsAMS_Cremaschi.pdf
  file_size: 326471
  relation: main_file
  success: 1
file_date_updated: 2023-01-26T13:02:07Z
has_accepted_license: '1'
intvolume: '         9'
issue: '43'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 445-459
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
publication: Proceedings of the American Mathematical Society, Series B
publication_identifier:
  issn:
  - 2330-1511
publication_status: published
publisher: American Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Effective contraction of Skinning maps
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2022'
...
---
_id: '12178'
abstract:
- lang: eng
  text: In this paper we consider the stochastic primitive equation for geophysical
    flows subject to transport noise and turbulent pressure. Admitting very rough
    noise terms, the global existence and uniqueness of solutions to this stochastic
    partial differential equation are proven using stochastic maximal L² regularity,
    the theory of critical spaces for stochastic evolution equations, and global a
    priori bounds. Compared to other results in this direction, we do not need any
    smallness assumption on the transport noise which acts directly on the velocity
    field and we also allow rougher noise terms. The adaptation to Stratonovich type
    noise and, more generally, to variable viscosity and/or conductivity are discussed
    as well.
acknowledgement: The authors thank the anonymous referees for their helpful comments
  and suggestions. Open Access funding enabled and organized by Projekt DEAL.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Antonio
  full_name: Agresti, Antonio
  id: 673cd0cc-9b9a-11eb-b144-88f30e1fbb72
  last_name: Agresti
  orcid: 0000-0002-9573-2962
- first_name: Matthias
  full_name: Hieber, Matthias
  last_name: Hieber
- first_name: Amru
  full_name: Hussein, Amru
  last_name: Hussein
- first_name: Martin
  full_name: Saal, Martin
  last_name: Saal
citation:
  ama: 'Agresti A, Hieber M, Hussein A, Saal M. The stochastic primitive equations
    with transport noise and turbulent pressure. <i>Stochastics and Partial Differential
    Equations: Analysis and Computations</i>. 2022. doi:<a href="https://doi.org/10.1007/s40072-022-00277-3">10.1007/s40072-022-00277-3</a>'
  apa: 'Agresti, A., Hieber, M., Hussein, A., &#38; Saal, M. (2022). The stochastic
    primitive equations with transport noise and turbulent pressure. <i>Stochastics
    and Partial Differential Equations: Analysis and Computations</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s40072-022-00277-3">https://doi.org/10.1007/s40072-022-00277-3</a>'
  chicago: 'Agresti, Antonio, Matthias Hieber, Amru Hussein, and Martin Saal. “The
    Stochastic Primitive Equations with Transport Noise and Turbulent Pressure.” <i>Stochastics
    and Partial Differential Equations: Analysis and Computations</i>. Springer Nature,
    2022. <a href="https://doi.org/10.1007/s40072-022-00277-3">https://doi.org/10.1007/s40072-022-00277-3</a>.'
  ieee: 'A. Agresti, M. Hieber, A. Hussein, and M. Saal, “The stochastic primitive
    equations with transport noise and turbulent pressure,” <i>Stochastics and Partial
    Differential Equations: Analysis and Computations</i>. Springer Nature, 2022.'
  ista: 'Agresti A, Hieber M, Hussein A, Saal M. 2022. The stochastic primitive equations
    with transport noise and turbulent pressure. Stochastics and Partial Differential
    Equations: Analysis and Computations.'
  mla: 'Agresti, Antonio, et al. “The Stochastic Primitive Equations with Transport
    Noise and Turbulent Pressure.” <i>Stochastics and Partial Differential Equations:
    Analysis and Computations</i>, Springer Nature, 2022, doi:<a href="https://doi.org/10.1007/s40072-022-00277-3">10.1007/s40072-022-00277-3</a>.'
  short: 'A. Agresti, M. Hieber, A. Hussein, M. Saal, Stochastics and Partial Differential
    Equations: Analysis and Computations (2022).'
date_created: 2023-01-12T12:12:29Z
date_published: 2022-10-27T00:00:00Z
date_updated: 2023-08-16T09:11:38Z
day: '27'
department:
- _id: JuFi
doi: 10.1007/s40072-022-00277-3
external_id:
  isi:
  - '000874389000001'
isi: 1
keyword:
- Applied Mathematics
- Modeling and Simulation
- Statistics and Probability
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1007/s40072-022-00277-3
month: '10'
oa: 1
oa_version: Published Version
publication: 'Stochastics and Partial Differential Equations: Analysis and Computations'
publication_identifier:
  eissn:
  - 2194-041X
  issn:
  - 2194-0401
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The stochastic primitive equations with transport noise and turbulent pressure
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '12179'
abstract:
- lang: eng
  text: We derive an accurate lower tail estimate on the lowest singular value σ1(X−z)
    of a real Gaussian (Ginibre) random matrix X shifted by a complex parameter z.
    Such shift effectively changes the upper tail behavior of the condition number
    κ(X−z) from the slower (κ(X−z)≥t)≲1/t decay typical for real Ginibre matrices
    to the faster 1/t2 decay seen for complex Ginibre matrices as long as z is away
    from the real axis. This sharpens and resolves a recent conjecture in [J. Banks
    et al., https://arxiv.org/abs/2005.08930, 2020] on the regularizing effect of
    the real Ginibre ensemble with a genuinely complex shift. As a consequence we
    obtain an improved upper bound on the eigenvalue condition numbers (known also
    as the eigenvector overlaps) for real Ginibre matrices. The main technical tool
    is a rigorous supersymmetric analysis from our earlier work [Probab. Math. Phys.,
    1 (2020), pp. 101--146].
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Dominik J
  full_name: Schröder, Dominik J
  id: 408ED176-F248-11E8-B48F-1D18A9856A87
  last_name: Schröder
  orcid: 0000-0002-2904-1856
citation:
  ama: Cipolloni G, Erdös L, Schröder DJ. On the condition number of the shifted real
    Ginibre ensemble. <i>SIAM Journal on Matrix Analysis and Applications</i>. 2022;43(3):1469-1487.
    doi:<a href="https://doi.org/10.1137/21m1424408">10.1137/21m1424408</a>
  apa: Cipolloni, G., Erdös, L., &#38; Schröder, D. J. (2022). On the condition number
    of the shifted real Ginibre ensemble. <i>SIAM Journal on Matrix Analysis and Applications</i>.
    Society for Industrial and Applied Mathematics. <a href="https://doi.org/10.1137/21m1424408">https://doi.org/10.1137/21m1424408</a>
  chicago: Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “On the Condition
    Number of the Shifted Real Ginibre Ensemble.” <i>SIAM Journal on Matrix Analysis
    and Applications</i>. Society for Industrial and Applied Mathematics, 2022. <a
    href="https://doi.org/10.1137/21m1424408">https://doi.org/10.1137/21m1424408</a>.
  ieee: G. Cipolloni, L. Erdös, and D. J. Schröder, “On the condition number of the
    shifted real Ginibre ensemble,” <i>SIAM Journal on Matrix Analysis and Applications</i>,
    vol. 43, no. 3. Society for Industrial and Applied Mathematics, pp. 1469–1487,
    2022.
  ista: Cipolloni G, Erdös L, Schröder DJ. 2022. On the condition number of the shifted
    real Ginibre ensemble. SIAM Journal on Matrix Analysis and Applications. 43(3),
    1469–1487.
  mla: Cipolloni, Giorgio, et al. “On the Condition Number of the Shifted Real Ginibre
    Ensemble.” <i>SIAM Journal on Matrix Analysis and Applications</i>, vol. 43, no.
    3, Society for Industrial and Applied Mathematics, 2022, pp. 1469–87, doi:<a href="https://doi.org/10.1137/21m1424408">10.1137/21m1424408</a>.
  short: G. Cipolloni, L. Erdös, D.J. Schröder, SIAM Journal on Matrix Analysis and
    Applications 43 (2022) 1469–1487.
date_created: 2023-01-12T12:12:38Z
date_published: 2022-07-01T00:00:00Z
date_updated: 2023-01-27T06:56:06Z
day: '01'
department:
- _id: LaEr
doi: 10.1137/21m1424408
external_id:
  arxiv:
  - '2105.13719'
intvolume: '        43'
issue: '3'
keyword:
- Analysis
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2105.13719
month: '07'
oa: 1
oa_version: Preprint
page: 1469-1487
publication: SIAM Journal on Matrix Analysis and Applications
publication_identifier:
  eissn:
  - 1095-7162
  issn:
  - 0895-4798
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the condition number of the shifted real Ginibre ensemble
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2022'
...
---
_id: '12182'
abstract:
- lang: eng
  text: 'Online algorithms make decisions based on past inputs, with the goal of being
    competitive against an algorithm that sees also future inputs. In this work, we
    introduce time-local online algorithms; these are online algorithms in which the
    output at any given time is a function of only T latest inputs. Our main observation
    is that time-local online algorithms are closely connected to local distributed
    graph algorithms: distributed algorithms make decisions based on the local information
    in the spatial dimension, while time-local online algorithms make decisions based
    on the local information in the temporal dimension. We formalize this connection,
    and show how we can directly use the tools developed to study distributed approximability
    of graph optimization problems to prove upper and lower bounds on the competitive
    ratio achieved with time-local online algorithms. Moreover, we show how to use
    computational techniques to synthesize optimal time-local algorithms.'
acknowledgement: "This research has received funding from the German Research Foundation
  (DFG), grant\r\n470029389 (FlexNets), 2021-2024, and the Marie Skłodowska-Curie
  grant agreement No. 840605."
article_number: '52'
article_processing_charge: No
author:
- first_name: Maciej
  full_name: Pacut, Maciej
  last_name: Pacut
- first_name: Mahmoud
  full_name: Parham, Mahmoud
  last_name: Parham
- first_name: Joel
  full_name: Rybicki, Joel
  id: 334EFD2E-F248-11E8-B48F-1D18A9856A87
  last_name: Rybicki
  orcid: 0000-0002-6432-6646
- first_name: Stefan
  full_name: Schmid, Stefan
  last_name: Schmid
- first_name: Jukka
  full_name: Suomela, Jukka
  last_name: Suomela
- first_name: Aleksandr
  full_name: Tereshchenko, Aleksandr
  last_name: Tereshchenko
citation:
  ama: 'Pacut M, Parham M, Rybicki J, Schmid S, Suomela J, Tereshchenko A. Brief announcement:
    Temporal locality in online algorithms. In: <i>36th International Symposium on
    Distributed Computing</i>. Vol 246. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
    2022. doi:<a href="https://doi.org/10.4230/LIPIcs.DISC.2022.52">10.4230/LIPIcs.DISC.2022.52</a>'
  apa: 'Pacut, M., Parham, M., Rybicki, J., Schmid, S., Suomela, J., &#38; Tereshchenko,
    A. (2022). Brief announcement: Temporal locality in online algorithms. In <i>36th
    International Symposium on Distributed Computing</i> (Vol. 246). Augusta, GA,
    United States: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPIcs.DISC.2022.52">https://doi.org/10.4230/LIPIcs.DISC.2022.52</a>'
  chicago: 'Pacut, Maciej, Mahmoud Parham, Joel Rybicki, Stefan Schmid, Jukka Suomela,
    and Aleksandr Tereshchenko. “Brief Announcement: Temporal Locality in Online Algorithms.”
    In <i>36th International Symposium on Distributed Computing</i>, Vol. 246. Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2022. <a href="https://doi.org/10.4230/LIPIcs.DISC.2022.52">https://doi.org/10.4230/LIPIcs.DISC.2022.52</a>.'
  ieee: 'M. Pacut, M. Parham, J. Rybicki, S. Schmid, J. Suomela, and A. Tereshchenko,
    “Brief announcement: Temporal locality in online algorithms,” in <i>36th International
    Symposium on Distributed Computing</i>, Augusta, GA, United States, 2022, vol.
    246.'
  ista: 'Pacut M, Parham M, Rybicki J, Schmid S, Suomela J, Tereshchenko A. 2022.
    Brief announcement: Temporal locality in online algorithms. 36th International
    Symposium on Distributed Computing. DISC: Symposium on Distributed Computing vol.
    246, 52.'
  mla: 'Pacut, Maciej, et al. “Brief Announcement: Temporal Locality in Online Algorithms.”
    <i>36th International Symposium on Distributed Computing</i>, vol. 246, 52, Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2022, doi:<a href="https://doi.org/10.4230/LIPIcs.DISC.2022.52">10.4230/LIPIcs.DISC.2022.52</a>.'
  short: M. Pacut, M. Parham, J. Rybicki, S. Schmid, J. Suomela, A. Tereshchenko,
    in:, 36th International Symposium on Distributed Computing, Schloss Dagstuhl -
    Leibniz-Zentrum für Informatik, 2022.
conference:
  end_date: 2022-10-27
  location: Augusta, GA, United States
  name: 'DISC: Symposium on Distributed Computing'
  start_date: 2022-10-25
date_created: 2023-01-13T11:06:28Z
date_published: 2022-10-17T00:00:00Z
date_updated: 2023-01-27T06:59:29Z
day: '17'
ddc:
- '000'
department:
- _id: DaAl
doi: 10.4230/LIPIcs.DISC.2022.52
ec_funded: 1
file:
- access_level: open_access
  checksum: 11bbb56f68a00f2cf6bcce6cc7f5c5f9
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-27T06:58:02Z
  date_updated: 2023-01-27T06:58:02Z
  file_id: '12409'
  file_name: 2022_LIPICs_Pacut.pdf
  file_size: 524804
  relation: main_file
  success: 1
file_date_updated: 2023-01-27T06:58:02Z
has_accepted_license: '1'
intvolume: '       246'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 26A5D39A-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '840605'
  name: Coordination in constrained and natural distributed systems
publication: 36th International Symposium on Distributed Computing
publication_identifier:
  eisbn:
  - '9783959772556'
  eissn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Brief announcement: Temporal locality in online algorithms'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 246
year: '2022'
...
---
_id: '12184'
abstract:
- lang: eng
  text: We review recent results on adiabatic theory for ground states of extended
    gapped fermionic lattice systems under several different assumptions. More precisely,
    we present generalized super-adiabatic theorems for extended but finite and infinite
    systems, assuming either a uniform gap or a gap in the bulk above the unperturbed
    ground state. The goal of this Review is to provide an overview of these adiabatic
    theorems and briefly outline the main ideas and techniques required in their proofs.
acknowledgement: "It is a pleasure to thank Stefan Teufel for numerous interesting
  discussions, fruitful collaboration, and many helpful comments on an earlier version
  of the manuscript. J.H. acknowledges partial financial support from the ERC Advanced
  Grant No. 101020331 “Random\r\nmatrices beyond Wigner-Dyson-Mehta.” T.W. acknowledges
  financial support from the DFG research unit FOR 5413 “Long-range interacting quantum
  spin systems out of equilibrium: Experiment, Theory and Mathematics.\" "
article_number: '121101'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
- first_name: Tom
  full_name: Wessel, Tom
  last_name: Wessel
citation:
  ama: Henheik SJ, Wessel T. On adiabatic theory for extended fermionic lattice systems.
    <i>Journal of Mathematical Physics</i>. 2022;63(12). doi:<a href="https://doi.org/10.1063/5.0123441">10.1063/5.0123441</a>
  apa: Henheik, S. J., &#38; Wessel, T. (2022). On adiabatic theory for extended fermionic
    lattice systems. <i>Journal of Mathematical Physics</i>. AIP Publishing. <a href="https://doi.org/10.1063/5.0123441">https://doi.org/10.1063/5.0123441</a>
  chicago: Henheik, Sven Joscha, and Tom Wessel. “On Adiabatic Theory for Extended
    Fermionic Lattice Systems.” <i>Journal of Mathematical Physics</i>. AIP Publishing,
    2022. <a href="https://doi.org/10.1063/5.0123441">https://doi.org/10.1063/5.0123441</a>.
  ieee: S. J. Henheik and T. Wessel, “On adiabatic theory for extended fermionic lattice
    systems,” <i>Journal of Mathematical Physics</i>, vol. 63, no. 12. AIP Publishing,
    2022.
  ista: Henheik SJ, Wessel T. 2022. On adiabatic theory for extended fermionic lattice
    systems. Journal of Mathematical Physics. 63(12), 121101.
  mla: Henheik, Sven Joscha, and Tom Wessel. “On Adiabatic Theory for Extended Fermionic
    Lattice Systems.” <i>Journal of Mathematical Physics</i>, vol. 63, no. 12, 121101,
    AIP Publishing, 2022, doi:<a href="https://doi.org/10.1063/5.0123441">10.1063/5.0123441</a>.
  short: S.J. Henheik, T. Wessel, Journal of Mathematical Physics 63 (2022).
date_created: 2023-01-15T23:00:52Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2023-08-04T09:14:57Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1063/5.0123441
ec_funded: 1
external_id:
  arxiv:
  - '2208.12220'
  isi:
  - '000905776200001'
file:
- access_level: open_access
  checksum: 213b93750080460718c050e4967cfdb4
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-27T07:10:52Z
  date_updated: 2023-01-27T07:10:52Z
  file_id: '12410'
  file_name: 2022_JourMathPhysics_Henheik2.pdf
  file_size: 5251092
  relation: main_file
  success: 1
file_date_updated: 2023-01-27T07:10:52Z
has_accepted_license: '1'
intvolume: '        63'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Journal of Mathematical Physics
publication_identifier:
  issn:
  - 0022-2488
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: On adiabatic theory for extended fermionic lattice systems
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 63
year: '2022'
...
---
_id: '12208'
abstract:
- lang: eng
  text: The inadequate understanding of the mechanisms that reversibly convert molecular
    sulfur (S) into lithium sulfide (Li<jats:sub>2</jats:sub>S) via soluble polysulfides
    (PSs) formation impedes the development of high-performance lithium-sulfur (Li-S)
    batteries with non-aqueous electrolyte solutions. Here, we use operando small
    and wide angle X-ray scattering and operando small angle neutron scattering (SANS)
    measurements to track the nucleation, growth and dissolution of solid deposits
    from atomic to sub-micron scales during real-time Li-S cell operation. In particular,
    stochastic modelling based on the SANS data allows quantifying the nanoscale phase
    evolution during battery cycling. We show that next to nano-crystalline Li<jats:sub>2</jats:sub>S
    the deposit comprises solid short-chain PSs particles. The analysis of the experimental
    data suggests that initially, Li<jats:sub>2</jats:sub>S<jats:sub>2</jats:sub>
    precipitates from the solution and then is partially converted via solid-state
    electroreduction to Li<jats:sub>2</jats:sub>S. We further demonstrate that mass
    transport, rather than electron transport through a thin passivating film, limits
    the discharge capacity and rate performance in Li-S cells.
acknowledgement: "This project has received funding from the European Union’s Horizon
  2020 research and innovation program under the Marie Skłodowska-Curie grant NanoEvolution,
  grant agreement No 894042. The authors acknowledge the CERIC-ERIC Consortium for
  the access to the Austrian SAXS beamline and TU Graz for support through the Lead
  Project LP-03.\r\nLikewise, the use of SOMAPP Lab, a core facility supported by
  the Austrian Federal Ministry of Education, Science and Research, the Graz University
  of Technology, the University of Graz, and Anton Paar GmbH is acknowledged. In addition,
  the authors acknowledge access to the D-22SANS beamline at the ILL neutron source.
  Electron microscopy measurements were performed at the Scientific Scenter for Optical
  and Electron Microscopy (ScopeM) of the Swiss Federal Institute of Technology. C.P.
  and J.M.M. thank A. Senol for her support with the SANS\r\nbeamtime preparation.
  S.D.T, A.V. and R.D. acknowledge the financial support by the Slovenian Research
  Agency (ARRS) research core funding P2-0393 and P2-0423. Furthermore, A.V. acknowledge
  the funding from the Slovenian Research Agency, research project Z2−1863.\r\nS.A.F.
  is indebted to IST Austria for support. "
article_number: '6326'
article_processing_charge: No
article_type: original
author:
- first_name: Christian
  full_name: Prehal, Christian
  last_name: Prehal
- first_name: Jean-Marc
  full_name: von Mentlen, Jean-Marc
  last_name: von Mentlen
- first_name: Sara
  full_name: Drvarič Talian, Sara
  last_name: Drvarič Talian
- first_name: Alen
  full_name: Vizintin, Alen
  last_name: Vizintin
- first_name: Robert
  full_name: Dominko, Robert
  last_name: Dominko
- first_name: Heinz
  full_name: Amenitsch, Heinz
  last_name: Amenitsch
- first_name: Lionel
  full_name: Porcar, Lionel
  last_name: Porcar
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
- first_name: Vanessa
  full_name: Wood, Vanessa
  last_name: Wood
citation:
  ama: Prehal C, von Mentlen J-M, Drvarič Talian S, et al. On the nanoscale structural
    evolution of solid discharge products in lithium-sulfur batteries using operando
    scattering. <i>Nature Communications</i>. 2022;13. doi:<a href="https://doi.org/10.1038/s41467-022-33931-4">10.1038/s41467-022-33931-4</a>
  apa: Prehal, C., von Mentlen, J.-M., Drvarič Talian, S., Vizintin, A., Dominko,
    R., Amenitsch, H., … Wood, V. (2022). On the nanoscale structural evolution of
    solid discharge products in lithium-sulfur batteries using operando scattering.
    <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-022-33931-4">https://doi.org/10.1038/s41467-022-33931-4</a>
  chicago: Prehal, Christian, Jean-Marc von Mentlen, Sara Drvarič Talian, Alen Vizintin,
    Robert Dominko, Heinz Amenitsch, Lionel Porcar, Stefan Alexander Freunberger,
    and Vanessa Wood. “On the Nanoscale Structural Evolution of Solid Discharge Products
    in Lithium-Sulfur Batteries Using Operando Scattering.” <i>Nature Communications</i>.
    Springer Nature, 2022. <a href="https://doi.org/10.1038/s41467-022-33931-4">https://doi.org/10.1038/s41467-022-33931-4</a>.
  ieee: C. Prehal <i>et al.</i>, “On the nanoscale structural evolution of solid discharge
    products in lithium-sulfur batteries using operando scattering,” <i>Nature Communications</i>,
    vol. 13. Springer Nature, 2022.
  ista: Prehal C, von Mentlen J-M, Drvarič Talian S, Vizintin A, Dominko R, Amenitsch
    H, Porcar L, Freunberger SA, Wood V. 2022. On the nanoscale structural evolution
    of solid discharge products in lithium-sulfur batteries using operando scattering.
    Nature Communications. 13, 6326.
  mla: Prehal, Christian, et al. “On the Nanoscale Structural Evolution of Solid Discharge
    Products in Lithium-Sulfur Batteries Using Operando Scattering.” <i>Nature Communications</i>,
    vol. 13, 6326, Springer Nature, 2022, doi:<a href="https://doi.org/10.1038/s41467-022-33931-4">10.1038/s41467-022-33931-4</a>.
  short: C. Prehal, J.-M. von Mentlen, S. Drvarič Talian, A. Vizintin, R. Dominko,
    H. Amenitsch, L. Porcar, S.A. Freunberger, V. Wood, Nature Communications 13 (2022).
date_created: 2023-01-16T09:45:09Z
date_published: 2022-10-24T00:00:00Z
date_updated: 2023-08-04T09:15:31Z
day: '24'
ddc:
- '540'
department:
- _id: StFr
doi: 10.1038/s41467-022-33931-4
external_id:
  isi:
  - '000871563700006'
  pmid:
  - '36280671'
file:
- access_level: open_access
  checksum: 5034336dbf0f860030ef745c08df9e0e
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-27T07:19:11Z
  date_updated: 2023-01-27T07:19:11Z
  file_id: '12411'
  file_name: 2022_NatureCommunications_Prehal.pdf
  file_size: 4216931
  relation: main_file
  success: 1
file_date_updated: 2023-01-27T07:19:11Z
has_accepted_license: '1'
intvolume: '        13'
isi: 1
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
- Multidisciplinary
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the nanoscale structural evolution of solid discharge products in lithium-sulfur
  batteries using operando scattering
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 13
year: '2022'
...
---
_id: '12209'
abstract:
- lang: eng
  text: Embryo development requires biochemical signalling to generate patterns of
    cell fates and active mechanical forces to drive tissue shape changes. However,
    how these processes are coordinated, and how tissue patterning is preserved despite
    the cellular flows occurring during morphogenesis, remains poorly understood.
    Gastrulation is a crucial embryonic stage that involves both patterning and internalization
    of the mesendoderm germ layer tissue. Here we show that, in zebrafish embryos,
    a gradient in Nodal signalling orchestrates pattern-preserving internalization
    movements by triggering a motility-driven unjamming transition. In addition to
    its role as a morphogen determining embryo patterning, graded Nodal signalling
    mechanically subdivides the mesendoderm into a small fraction of highly protrusive
    leader cells, able to autonomously internalize via local unjamming, and less protrusive
    followers, which need to be pulled inwards by the leaders. The Nodal gradient
    further enforces a code of preferential adhesion coupling leaders to their immediate
    followers, resulting in a collective and ordered mode of internalization that
    preserves mesendoderm patterning. Integrating this dual mechanical role of Nodal
    signalling into minimal active particle simulations quantitatively predicts both
    physiological and experimentally perturbed internalization movements. This provides
    a quantitative framework for how a morphogen-encoded unjamming transition can
    bidirectionally couple tissue mechanics with patterning during complex three-dimensional
    morphogenesis.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: "We thank K. Sampath, A. Pauli and Y. Bellaїche for feedback on the
  manuscript. We also thank the members of the Heisenberg group, in particular A.
  Schauer and F. Nur Arslan, for help, technical advice and discussions, and the Bioimaging
  and Life Science facilities at IST\r\nAustria for continuous support. We thank C.
  Flandoli for the artwork in the figures. This work was supported by postdoctoral
  fellowships from EMBO (LTF-850-2017) and HFSP (LT000429/2018-L2) to D.P. and the
  European Union (European Research Council starting grant 851288 to É.H. and European
  Research Council advanced grant 742573 to C.-P.H.)."
article_processing_charge: No
article_type: original
author:
- first_name: Diana C
  full_name: Nunes Pinheiro, Diana C
  id: 2E839F16-F248-11E8-B48F-1D18A9856A87
  last_name: Nunes Pinheiro
  orcid: 0000-0003-4333-7503
- first_name: Roland
  full_name: Kardos, Roland
  id: 4039350E-F248-11E8-B48F-1D18A9856A87
  last_name: Kardos
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Nunes Pinheiro DC, Kardos R, Hannezo EB, Heisenberg C-PJ. Morphogen gradient
    orchestrates pattern-preserving tissue morphogenesis via motility-driven unjamming.
    <i>Nature Physics</i>. 2022;18(12):1482-1493. doi:<a href="https://doi.org/10.1038/s41567-022-01787-6">10.1038/s41567-022-01787-6</a>
  apa: Nunes Pinheiro, D. C., Kardos, R., Hannezo, E. B., &#38; Heisenberg, C.-P.
    J. (2022). Morphogen gradient orchestrates pattern-preserving tissue morphogenesis
    via motility-driven unjamming. <i>Nature Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/s41567-022-01787-6">https://doi.org/10.1038/s41567-022-01787-6</a>
  chicago: Nunes Pinheiro, Diana C, Roland Kardos, Edouard B Hannezo, and Carl-Philipp
    J Heisenberg. “Morphogen Gradient Orchestrates Pattern-Preserving Tissue Morphogenesis
    via Motility-Driven Unjamming.” <i>Nature Physics</i>. Springer Nature, 2022.
    <a href="https://doi.org/10.1038/s41567-022-01787-6">https://doi.org/10.1038/s41567-022-01787-6</a>.
  ieee: D. C. Nunes Pinheiro, R. Kardos, E. B. Hannezo, and C.-P. J. Heisenberg, “Morphogen
    gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven
    unjamming,” <i>Nature Physics</i>, vol. 18, no. 12. Springer Nature, pp. 1482–1493,
    2022.
  ista: Nunes Pinheiro DC, Kardos R, Hannezo EB, Heisenberg C-PJ. 2022. Morphogen
    gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven
    unjamming. Nature Physics. 18(12), 1482–1493.
  mla: Nunes Pinheiro, Diana C., et al. “Morphogen Gradient Orchestrates Pattern-Preserving
    Tissue Morphogenesis via Motility-Driven Unjamming.” <i>Nature Physics</i>, vol.
    18, no. 12, Springer Nature, 2022, pp. 1482–93, doi:<a href="https://doi.org/10.1038/s41567-022-01787-6">10.1038/s41567-022-01787-6</a>.
  short: D.C. Nunes Pinheiro, R. Kardos, E.B. Hannezo, C.-P.J. Heisenberg, Nature
    Physics 18 (2022) 1482–1493.
date_created: 2023-01-16T09:45:19Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2023-08-04T09:15:58Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
- _id: EdHa
doi: 10.1038/s41567-022-01787-6
ec_funded: 1
external_id:
  isi:
  - '000871319900002'
file:
- access_level: open_access
  checksum: c86a8e8d80d1bfc46d56a01e88a2526a
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-27T07:32:01Z
  date_updated: 2023-01-27T07:32:01Z
  file_id: '12412'
  file_name: 2022_NaturePhysics_Pinheiro.pdf
  file_size: 36703569
  relation: main_file
  success: 1
file_date_updated: 2023-01-27T07:32:01Z
has_accepted_license: '1'
intvolume: '        18'
isi: 1
issue: '12'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 1482-1493
project:
- _id: 26520D1E-B435-11E9-9278-68D0E5697425
  grant_number: ALTF 850-2017
  name: Coordination of mesendoderm cell fate specification and internalization during
    zebrafish gastrulation
- _id: 26520D1E-B435-11E9-9278-68D0E5697425
  grant_number: ALTF 850-2017
  name: Coordination of mesendoderm cell fate specification and internalization during
    zebrafish gastrulation
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
- _id: 260F1432-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742573'
  name: Interaction and feedback between cell mechanics and fate specification in
    vertebrate gastrulation
publication: Nature Physics
publication_identifier:
  eissn:
  - 1745-2481
  issn:
  - 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via
  motility-driven unjamming
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 18
year: '2022'
...
---
_id: '12210'
abstract:
- lang: eng
  text: "The aim of this paper is to find new estimates for the norms of functions
    of a (minus) distinguished Laplace operator L on the ‘ax+b’ groups. The central
    part is devoted to spectrally localized wave propagators, that is, functions of
    the type ψ(L−−√)exp(itL−−√), with ψ∈C0(R). We show that for t→+∞, the convolution
    kernel kt of this operator satisfies\r\n∥kt∥1≍t,∥kt∥∞≍1,\r\nso that the upper
    estimates of D. Müller and C. Thiele (Studia Math., 2007) are sharp. As a necessary
    component, we recall the Plancherel density of L and spend certain time presenting
    and comparing different approaches to its calculation. Using its explicit form,
    we estimate uniform norms of several functions of the shifted Laplace-Beltrami
    operator Δ~, closely related to L. The functions include in particular exp(−tΔ~γ),
    t>0,γ>0, and (Δ~−z)s, with complex z, s."
acknowledgement: "Yu. K. thanks Professor Waldemar Hebisch for valuable discussions
  on the general context of multipliers on Lie groups. This work was started during
  an ICL-CNRS fellowship of the second\r\nnamed author at the Imperial College London.
  Yu. K. is supported by the ANR-19-CE40-0002 grant of the French National Research
  Agency (ANR). H. Z. is supported by the European Union’s Horizon 2020 research and
  innovation programme under the Marie Skłodowska-Curie grant agreement No. 754411
  and the Lise Meitner fellowship, Austrian Science Fund (FWF) M3337. R. A. was supported
  by the EPSRC grant EP/R003025. M. R. is supported by the EPSRC grant EP/R003025/2
  and by the FWO Odysseus 1 grant G.0H94.18N: Analysis and Partial Differential Equations."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Rauan
  full_name: Akylzhanov, Rauan
  last_name: Akylzhanov
- first_name: Yulia
  full_name: Kuznetsova, Yulia
  last_name: Kuznetsova
- first_name: Michael
  full_name: Ruzhansky, Michael
  last_name: Ruzhansky
- first_name: Haonan
  full_name: Zhang, Haonan
  id: D8F41E38-9E66-11E9-A9E2-65C2E5697425
  last_name: Zhang
citation:
  ama: Akylzhanov R, Kuznetsova Y, Ruzhansky M, Zhang H. Norms of certain functions
    of a distinguished Laplacian on the ax + b groups. <i>Mathematische Zeitschrift</i>.
    2022;302(4):2327-2352. doi:<a href="https://doi.org/10.1007/s00209-022-03143-z">10.1007/s00209-022-03143-z</a>
  apa: Akylzhanov, R., Kuznetsova, Y., Ruzhansky, M., &#38; Zhang, H. (2022). Norms
    of certain functions of a distinguished Laplacian on the ax + b groups. <i>Mathematische
    Zeitschrift</i>. Springer Nature. <a href="https://doi.org/10.1007/s00209-022-03143-z">https://doi.org/10.1007/s00209-022-03143-z</a>
  chicago: Akylzhanov, Rauan, Yulia Kuznetsova, Michael Ruzhansky, and Haonan Zhang.
    “Norms of Certain Functions of a Distinguished Laplacian on the Ax + b Groups.”
    <i>Mathematische Zeitschrift</i>. Springer Nature, 2022. <a href="https://doi.org/10.1007/s00209-022-03143-z">https://doi.org/10.1007/s00209-022-03143-z</a>.
  ieee: R. Akylzhanov, Y. Kuznetsova, M. Ruzhansky, and H. Zhang, “Norms of certain
    functions of a distinguished Laplacian on the ax + b groups,” <i>Mathematische
    Zeitschrift</i>, vol. 302, no. 4. Springer Nature, pp. 2327–2352, 2022.
  ista: Akylzhanov R, Kuznetsova Y, Ruzhansky M, Zhang H. 2022. Norms of certain functions
    of a distinguished Laplacian on the ax + b groups. Mathematische Zeitschrift.
    302(4), 2327–2352.
  mla: Akylzhanov, Rauan, et al. “Norms of Certain Functions of a Distinguished Laplacian
    on the Ax + b Groups.” <i>Mathematische Zeitschrift</i>, vol. 302, no. 4, Springer
    Nature, 2022, pp. 2327–52, doi:<a href="https://doi.org/10.1007/s00209-022-03143-z">10.1007/s00209-022-03143-z</a>.
  short: R. Akylzhanov, Y. Kuznetsova, M. Ruzhansky, H. Zhang, Mathematische Zeitschrift
    302 (2022) 2327–2352.
date_created: 2023-01-16T09:45:31Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2023-08-04T09:22:14Z
day: '01'
department:
- _id: JaMa
doi: 10.1007/s00209-022-03143-z
ec_funded: 1
external_id:
  arxiv:
  - '2101.00584'
  isi:
  - '000859680700001'
intvolume: '       302'
isi: 1
issue: '4'
keyword:
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2101.00584
month: '12'
oa: 1
oa_version: Preprint
page: 2327-2352
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: eb958bca-77a9-11ec-83b8-c565cb50d8d6
  grant_number: M03337
  name: Curvature-dimension in noncommutative analysis
publication: Mathematische Zeitschrift
publication_identifier:
  eissn:
  - 1432-1823
  issn:
  - 0025-5874
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Norms of certain functions of a distinguished Laplacian on the ax + b groups
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 302
year: '2022'
...
---
_id: '12212'
abstract:
- lang: eng
  text: Alzheimer’s disease (AD) is characterized by a reorganization of brain activity
    determining network hyperexcitability and loss of synaptic plasticity. Precisely,
    a dysfunction in metabotropic GABAB receptor signalling through G protein-gated
    inwardly rectifying K+ (GIRK or Kir3) channels on the hippocampus has been postulated.
    Thus, we determined the impact of amyloid-β (Aβ) pathology in GIRK channel density,
    subcellular distribution, and its association with GABAB receptors in hippocampal
    CA1 pyramidal neurons from the APP/PS1 mouse model using quantitative SDS-digested
    freeze-fracture replica labelling (SDS-FRL) and proximity ligation in situ assay
    (P-LISA). In wild type mice, single SDS-FRL detection revealed a similar dendritic
    gradient for GIRK1 and GIRK2 in CA1 pyramidal cells, with higher densities in
    spines, and GIRK3 showed a lower and uniform distribution. Double SDS-FRL showed
    a co-clustering of GIRK2 and GIRK1 in post- and presynaptic compartments, but
    not for GIRK2 and GIRK3. Likewise, double GABAB1 and GIRK2 SDS-FRL detection displayed
    a high degree of co-clustering in nanodomains (40–50 nm) mostly in spines and
    axon terminals. In APP/PS1 mice, the density of GIRK2 and GIRK1, but not for GIRK3,
    was significantly reduced along the neuronal surface of CA1 pyramidal cells and
    in axon terminals contacting them. Importantly, GABAB1 and GIRK2 co-clustering
    was not present in APP/PS1 mice. Similarly, P-LISA experiments revealed a significant
    reduction in GABAB1 and GIRK2 interaction on the hippocampus of this animal model.
    Overall, our results provide compelling evidence showing a significant reduction
    on the cell surface density of pre- and postsynaptic GIRK1 and GIRK2, but not
    GIRK3, and a decline in GABAB receptors and GIRK2 channels co-clustering in hippocampal
    pyramidal neurons from APP/PS1 mice, thus suggesting that a disruption in the
    GABAB receptor–GIRK channel membrane assembly causes dysregulation in the GABAB
    signalling via GIRK channels in this AD animal model.
acknowledgement: "We thank Ms. Diane Latawiec for the English revision of the manuscript.
  Funding sources were the Spanish Ministerio de Economía y Competitividad, Junta
  de Comunidades de Castilla-La Mancha (Spain), and Life Science Innovation Center
  at University of Fukui. We thank Centres de Recerca de Catalunya (CERCA) Programme/Generalitat
  de Catalunya for IDIBELL institutional support. We thank Hitoshi Takagi and Takako
  Maegawa at the University of Fukui for their technical assistance on SDS-FRL experiments.\r\nThis
  work was supported by grants from the Spanish Ministerio de Economía y Competitividad
  (BFU2015-63769-R, RTI2018-095812-B-I00, and PID2021-125875OB-I00) and Junta de Comunidades
  de Castilla-La Mancha (SBPLY/17/180501/000229 and SBPLY/21/180501/000064) to RL,
  Life Science Innovation Center at University of Fukui and JSPS KAKENHI (Grant Numbers
  16H04662, 19H03323, and 20H05058) to YF, and Margarita Salas fellowship from Ministerio
  de Universidades and Universidad de Castilla-La Mancha to AMB."
article_number: '136'
article_processing_charge: No
article_type: original
author:
- first_name: Alejandro
  full_name: Martín-Belmonte, Alejandro
  last_name: Martín-Belmonte
- first_name: Carolina
  full_name: Aguado, Carolina
  last_name: Aguado
- first_name: Rocío
  full_name: Alfaro-Ruiz, Rocío
  last_name: Alfaro-Ruiz
- first_name: Ana Esther
  full_name: Moreno-Martínez, Ana Esther
  last_name: Moreno-Martínez
- first_name: Luis
  full_name: de la Ossa, Luis
  last_name: de la Ossa
- first_name: Ester
  full_name: Aso, Ester
  last_name: Aso
- first_name: Laura
  full_name: Gómez-Acero, Laura
  last_name: Gómez-Acero
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Yugo
  full_name: Fukazawa, Yugo
  last_name: Fukazawa
- first_name: Francisco
  full_name: Ciruela, Francisco
  last_name: Ciruela
- first_name: Rafael
  full_name: Luján, Rafael
  last_name: Luján
citation:
  ama: Martín-Belmonte A, Aguado C, Alfaro-Ruiz R, et al. Nanoscale alterations in
    GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice.
    <i>Alzheimer’s Research &#38; Therapy</i>. 2022;14. doi:<a href="https://doi.org/10.1186/s13195-022-01078-5">10.1186/s13195-022-01078-5</a>
  apa: Martín-Belmonte, A., Aguado, C., Alfaro-Ruiz, R., Moreno-Martínez, A. E., de
    la Ossa, L., Aso, E., … Luján, R. (2022). Nanoscale alterations in GABAB receptors
    and GIRK channel organization on the hippocampus of APP/PS1 mice. <i>Alzheimer’s
    Research &#38; Therapy</i>. Springer Nature. <a href="https://doi.org/10.1186/s13195-022-01078-5">https://doi.org/10.1186/s13195-022-01078-5</a>
  chicago: Martín-Belmonte, Alejandro, Carolina Aguado, Rocío Alfaro-Ruiz, Ana Esther
    Moreno-Martínez, Luis de la Ossa, Ester Aso, Laura Gómez-Acero, et al. “Nanoscale
    Alterations in GABAB Receptors and GIRK Channel Organization on the Hippocampus
    of APP/PS1 Mice.” <i>Alzheimer’s Research &#38; Therapy</i>. Springer Nature,
    2022. <a href="https://doi.org/10.1186/s13195-022-01078-5">https://doi.org/10.1186/s13195-022-01078-5</a>.
  ieee: A. Martín-Belmonte <i>et al.</i>, “Nanoscale alterations in GABAB receptors
    and GIRK channel organization on the hippocampus of APP/PS1 mice,” <i>Alzheimer’s
    Research &#38; Therapy</i>, vol. 14. Springer Nature, 2022.
  ista: Martín-Belmonte A, Aguado C, Alfaro-Ruiz R, Moreno-Martínez AE, de la Ossa
    L, Aso E, Gómez-Acero L, Shigemoto R, Fukazawa Y, Ciruela F, Luján R. 2022. Nanoscale
    alterations in GABAB receptors and GIRK channel organization on the hippocampus
    of APP/PS1 mice. Alzheimer’s Research &#38; Therapy. 14, 136.
  mla: Martín-Belmonte, Alejandro, et al. “Nanoscale Alterations in GABAB Receptors
    and GIRK Channel Organization on the Hippocampus of APP/PS1 Mice.” <i>Alzheimer’s
    Research &#38; Therapy</i>, vol. 14, 136, Springer Nature, 2022, doi:<a href="https://doi.org/10.1186/s13195-022-01078-5">10.1186/s13195-022-01078-5</a>.
  short: A. Martín-Belmonte, C. Aguado, R. Alfaro-Ruiz, A.E. Moreno-Martínez, L. de
    la Ossa, E. Aso, L. Gómez-Acero, R. Shigemoto, Y. Fukazawa, F. Ciruela, R. Luján,
    Alzheimer’s Research &#38; Therapy 14 (2022).
date_created: 2023-01-16T09:45:51Z
date_published: 2022-09-21T00:00:00Z
date_updated: 2023-08-04T09:23:10Z
day: '21'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1186/s13195-022-01078-5
external_id:
  isi:
  - '000857985500001'
file:
- access_level: open_access
  checksum: 88e49715ad6a1abf0fdb27efd65368dc
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-27T07:53:18Z
  date_updated: 2023-01-27T07:53:18Z
  file_id: '12413'
  file_name: 2022_AlzheimersResearch_MartinBelmont.pdf
  file_size: 11013325
  relation: main_file
  success: 1
file_date_updated: 2023-01-27T07:53:18Z
has_accepted_license: '1'
intvolume: '        14'
isi: 1
keyword:
- Cognitive Neuroscience
- Neurology (clinical)
- Neurology
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: Alzheimer's Research & Therapy
publication_identifier:
  issn:
  - 1758-9193
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nanoscale alterations in GABAB receptors and GIRK channel organization on the
  hippocampus of APP/PS1 mice
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 14
year: '2022'
...
---
_id: '12213'
abstract:
- lang: eng
  text: 'Motivated by properties-controlling potential of the strain, we investigate
    strain dependence of structure, electronic, and magnetic properties of Sr2IrO4
    using complementary theoretical tools: ab-initio calculations, analytical approaches
    (rigid octahedra picture, Slater-Koster integrals), and extended t−J model. We
    find that strain affects both Ir-Ir distance and Ir-O-Ir angle, and the rigid
    octahedra picture is not relevant. Second, we find fundamentally different behavior
    for compressive and tensile strain. One remarkable feature is the formation of
    two subsets of bond- and orbital-dependent carriers, a compass-like model, under
    compression. This originates from the strain-induced renormalization of the Ir-O-Ir
    superexchange and O on-site energy. We also show that under compressive (tensile)
    strain, Fermi surface becomes highly dispersive (relatively flat). Already at
    a tensile strain of 1.5%, we observe spectral weight redistribution, with the
    low-energy band acquiring almost purely singlet character. These results can be
    directly compared with future experiments.'
acknowledgement: E.M.P. thanks Eugenio Paris, Thorsten Schmitt, Krzysztof Wohlfeld,
  and other coauthors for an inspiring previous collaboration23, and is grateful to
  Gang Cao, Ambrose Seo, and Jungho Kim for insightful discussions. R.R. acknowledges
  helpful discussion with Sanjeev Kumar and Manuel Richter. This project has received
  funding from the European Union’s Horizon 2020 research and innovation program under
  the Marie Sklodowska-Curie grant agreement No 754411. C.C.C. acknowledges support
  from the U.S. National Science Foundation Award No. DMR-2142801.
article_number: '90'
article_processing_charge: No
article_type: original
author:
- first_name: Ekaterina
  full_name: Paerschke, Ekaterina
  id: 8275014E-6063-11E9-9B7F-6338E6697425
  last_name: Paerschke
  orcid: 0000-0003-0853-8182
- first_name: Wei-Chih
  full_name: Chen, Wei-Chih
  last_name: Chen
- first_name: Rajyavardhan
  full_name: Ray, Rajyavardhan
  last_name: Ray
- first_name: Cheng-Chien
  full_name: Chen, Cheng-Chien
  last_name: Chen
citation:
  ama: Paerschke E, Chen W-C, Ray R, Chen C-C. Evolution of electronic and magnetic
    properties of Sr₂IrO₄ under strain. <i>npj Quantum Materials</i>. 2022;7. doi:<a
    href="https://doi.org/10.1038/s41535-022-00496-w">10.1038/s41535-022-00496-w</a>
  apa: Paerschke, E., Chen, W.-C., Ray, R., &#38; Chen, C.-C. (2022). Evolution of
    electronic and magnetic properties of Sr₂IrO₄ under strain. <i>Npj Quantum Materials</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41535-022-00496-w">https://doi.org/10.1038/s41535-022-00496-w</a>
  chicago: Paerschke, Ekaterina, Wei-Chih Chen, Rajyavardhan Ray, and Cheng-Chien
    Chen. “Evolution of Electronic and Magnetic Properties of Sr₂IrO₄ under Strain.”
    <i>Npj Quantum Materials</i>. Springer Nature, 2022. <a href="https://doi.org/10.1038/s41535-022-00496-w">https://doi.org/10.1038/s41535-022-00496-w</a>.
  ieee: E. Paerschke, W.-C. Chen, R. Ray, and C.-C. Chen, “Evolution of electronic
    and magnetic properties of Sr₂IrO₄ under strain,” <i>npj Quantum Materials</i>,
    vol. 7. Springer Nature, 2022.
  ista: Paerschke E, Chen W-C, Ray R, Chen C-C. 2022. Evolution of electronic and
    magnetic properties of Sr₂IrO₄ under strain. npj Quantum Materials. 7, 90.
  mla: Paerschke, Ekaterina, et al. “Evolution of Electronic and Magnetic Properties
    of Sr₂IrO₄ under Strain.” <i>Npj Quantum Materials</i>, vol. 7, 90, Springer Nature,
    2022, doi:<a href="https://doi.org/10.1038/s41535-022-00496-w">10.1038/s41535-022-00496-w</a>.
  short: E. Paerschke, W.-C. Chen, R. Ray, C.-C. Chen, Npj Quantum Materials 7 (2022).
date_created: 2023-01-16T09:46:01Z
date_published: 2022-09-10T00:00:00Z
date_updated: 2023-08-04T09:23:43Z
day: '10'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1038/s41535-022-00496-w
ec_funded: 1
external_id:
  isi:
  - '000852381200003'
file:
- access_level: open_access
  checksum: d93b477b5b95c0d1b8f9fef90a81f565
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-27T07:59:27Z
  date_updated: 2023-01-27T07:59:27Z
  file_id: '12414'
  file_name: 2022_NPJ_Paerschke.pdf
  file_size: 1852598
  relation: main_file
  success: 1
file_date_updated: 2023-01-27T07:59:27Z
has_accepted_license: '1'
intvolume: '         7'
isi: 1
keyword:
- Condensed Matter Physics
- Electronic
- Optical and Magnetic Materials
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: npj Quantum Materials
publication_identifier:
  eissn:
  - 2397-4648
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1038/s41535-022-00510-1
scopus_import: '1'
status: public
title: Evolution of electronic and magnetic properties of Sr₂IrO₄ under strain
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 7
year: '2022'
...
---
_id: '12214'
abstract:
- lang: eng
  text: 'Motivated by Kloeckner’s result on the isometry group of the quadratic Wasserstein
    space W2(Rn), we describe the isometry group Isom(Wp(E)) for all parameters 0
    < p < ∞ and for all separable real Hilbert spaces E. In particular, we show that
    Wp(X) is isometrically rigid for all Polish space X whenever 0 < p < 1. This is
    a consequence of our more general result: we prove that W1(X) is isometrically
    rigid if X is a complete separable metric space that satisfies the strict triangle
    inequality. Furthermore, we show that this latter rigidity result does not generalise
    to parameters p > 1, by solving Kloeckner’s problem affirmatively on the existence
    of mass-splitting isometries. '
acknowledgement: "Geher was supported by the Leverhulme Trust Early Career Fellowship
  (ECF-2018-125), and also by the Hungarian National Research, Development and Innovation
  Office - NKFIH (grant no. K115383 and K134944).\r\nTitkos was supported by the Hungarian
  National Research, Development and Innovation Office - NKFIH (grant no. PD128374,
  grant no. K115383 and K134944), by the J´anos Bolyai Research Scholarship of the
  Hungarian Academy of Sciences, and by the UNKP-20-5-BGE-1 New National Excellence
  Program of the ´Ministry of Innovation and Technology.\r\nVirosztek was supported
  by the European Union’s Horizon 2020 research and innovation program under the Marie
  Sklodowska-Curie Grant Agreement No. 846294, by the Momentum program of the Hungarian
  Academy of Sciences under grant agreement no. LP2021-15/2021, and partially supported
  by the Hungarian National Research, Development and Innovation Office - NKFIH (grants
  no. K124152 and no. KH129601). "
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: György Pál
  full_name: Gehér, György Pál
  last_name: Gehér
- first_name: Tamás
  full_name: Titkos, Tamás
  last_name: Titkos
- first_name: Daniel
  full_name: Virosztek, Daniel
  id: 48DB45DA-F248-11E8-B48F-1D18A9856A87
  last_name: Virosztek
  orcid: 0000-0003-1109-5511
citation:
  ama: 'Gehér GP, Titkos T, Virosztek D. The isometry group of Wasserstein spaces:
    The Hilbertian case. <i>Journal of the London Mathematical Society</i>. 2022;106(4):3865-3894.
    doi:<a href="https://doi.org/10.1112/jlms.12676">10.1112/jlms.12676</a>'
  apa: 'Gehér, G. P., Titkos, T., &#38; Virosztek, D. (2022). The isometry group of
    Wasserstein spaces: The Hilbertian case. <i>Journal of the London Mathematical
    Society</i>. Wiley. <a href="https://doi.org/10.1112/jlms.12676">https://doi.org/10.1112/jlms.12676</a>'
  chicago: 'Gehér, György Pál, Tamás Titkos, and Daniel Virosztek. “The Isometry Group
    of Wasserstein Spaces: The Hilbertian Case.” <i>Journal of the London Mathematical
    Society</i>. Wiley, 2022. <a href="https://doi.org/10.1112/jlms.12676">https://doi.org/10.1112/jlms.12676</a>.'
  ieee: 'G. P. Gehér, T. Titkos, and D. Virosztek, “The isometry group of Wasserstein
    spaces: The Hilbertian case,” <i>Journal of the London Mathematical Society</i>,
    vol. 106, no. 4. Wiley, pp. 3865–3894, 2022.'
  ista: 'Gehér GP, Titkos T, Virosztek D. 2022. The isometry group of Wasserstein
    spaces: The Hilbertian case. Journal of the London Mathematical Society. 106(4),
    3865–3894.'
  mla: 'Gehér, György Pál, et al. “The Isometry Group of Wasserstein Spaces: The Hilbertian
    Case.” <i>Journal of the London Mathematical Society</i>, vol. 106, no. 4, Wiley,
    2022, pp. 3865–94, doi:<a href="https://doi.org/10.1112/jlms.12676">10.1112/jlms.12676</a>.'
  short: G.P. Gehér, T. Titkos, D. Virosztek, Journal of the London Mathematical Society
    106 (2022) 3865–3894.
date_created: 2023-01-16T09:46:13Z
date_published: 2022-09-18T00:00:00Z
date_updated: 2023-08-04T09:24:17Z
day: '18'
department:
- _id: LaEr
doi: 10.1112/jlms.12676
ec_funded: 1
external_id:
  arxiv:
  - '2102.02037'
  isi:
  - '000854878500001'
intvolume: '       106'
isi: 1
issue: '4'
keyword:
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2102.02037
month: '09'
oa: 1
oa_version: Preprint
page: 3865-3894
project:
- _id: 26A455A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '846294'
  name: Geometric study of Wasserstein spaces and free probability
publication: Journal of the London Mathematical Society
publication_identifier:
  eissn:
  - 1469-7750
  issn:
  - 0024-6107
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The isometry group of Wasserstein spaces: The Hilbertian case'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 106
year: '2022'
...
---
_id: '12216'
abstract:
- lang: eng
  text: Many trace inequalities can be expressed either as concavity/convexity theorems
    or as monotonicity theorems. A classic example is the joint convexity of the quantum
    relative entropy which is equivalent to the Data Processing Inequality. The latter
    says that quantum operations can never increase the relative entropy. The monotonicity
    versions often have many advantages, and often have direct physical application,
    as in the example just mentioned. Moreover, the monotonicity results are often
    valid for a larger class of maps than, say, quantum operations (which are completely
    positive). In this paper we prove several new monotonicity results, the first
    of which is a monotonicity theorem that has as a simple corollary a celebrated
    concavity theorem of Epstein. Our starting points are the monotonicity versions
    of the Lieb Concavity and the Lieb Convexity Theorems. We also give two new proofs
    of these in their general forms using interpolation. We then prove our new monotonicity
    theorems by several duality arguments.
acknowledgement: Work partially supported by the Lise Meitner fellowship, Austrian
  Science Fund (FWF) M3337.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Eric A.
  full_name: Carlen, Eric A.
  last_name: Carlen
- first_name: Haonan
  full_name: Zhang, Haonan
  id: D8F41E38-9E66-11E9-A9E2-65C2E5697425
  last_name: Zhang
citation:
  ama: Carlen EA, Zhang H. Monotonicity versions of Epstein’s concavity theorem and
    related inequalities. <i>Linear Algebra and its Applications</i>. 2022;654:289-310.
    doi:<a href="https://doi.org/10.1016/j.laa.2022.09.001">10.1016/j.laa.2022.09.001</a>
  apa: Carlen, E. A., &#38; Zhang, H. (2022). Monotonicity versions of Epstein’s concavity
    theorem and related inequalities. <i>Linear Algebra and Its Applications</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.laa.2022.09.001">https://doi.org/10.1016/j.laa.2022.09.001</a>
  chicago: Carlen, Eric A., and Haonan Zhang. “Monotonicity Versions of Epstein’s
    Concavity Theorem and Related Inequalities.” <i>Linear Algebra and Its Applications</i>.
    Elsevier, 2022. <a href="https://doi.org/10.1016/j.laa.2022.09.001">https://doi.org/10.1016/j.laa.2022.09.001</a>.
  ieee: E. A. Carlen and H. Zhang, “Monotonicity versions of Epstein’s concavity theorem
    and related inequalities,” <i>Linear Algebra and its Applications</i>, vol. 654.
    Elsevier, pp. 289–310, 2022.
  ista: Carlen EA, Zhang H. 2022. Monotonicity versions of Epstein’s concavity theorem
    and related inequalities. Linear Algebra and its Applications. 654, 289–310.
  mla: Carlen, Eric A., and Haonan Zhang. “Monotonicity Versions of Epstein’s Concavity
    Theorem and Related Inequalities.” <i>Linear Algebra and Its Applications</i>,
    vol. 654, Elsevier, 2022, pp. 289–310, doi:<a href="https://doi.org/10.1016/j.laa.2022.09.001">10.1016/j.laa.2022.09.001</a>.
  short: E.A. Carlen, H. Zhang, Linear Algebra and Its Applications 654 (2022) 289–310.
date_created: 2023-01-16T09:46:38Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2023-08-04T09:24:51Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1016/j.laa.2022.09.001
external_id:
  isi:
  - '000860689600014'
file:
- access_level: open_access
  checksum: cf3cb7e7e34baa967849f01d8f0c1ae4
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-27T08:08:39Z
  date_updated: 2023-01-27T08:08:39Z
  file_id: '12415'
  file_name: 2022_LinearAlgebra_Carlen.pdf
  file_size: 441184
  relation: main_file
  success: 1
file_date_updated: 2023-01-27T08:08:39Z
has_accepted_license: '1'
intvolume: '       654'
isi: 1
keyword:
- Discrete Mathematics and Combinatorics
- Geometry and Topology
- Numerical Analysis
- Algebra and Number Theory
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 289-310
project:
- _id: eb958bca-77a9-11ec-83b8-c565cb50d8d6
  grant_number: M03337
  name: Curvature-dimension in noncommutative analysis
publication: Linear Algebra and its Applications
publication_identifier:
  issn:
  - 0024-3795
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Monotonicity versions of Epstein's concavity theorem and related inequalities
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 654
year: '2022'
...
---
_id: '12217'
abstract:
- lang: eng
  text: The development dynamics and self-organization of glandular branched epithelia
    is of utmost importance for our understanding of diverse processes ranging from
    normal tissue growth to the growth of cancerous tissues. Using single primary
    murine pancreatic ductal adenocarcinoma (PDAC) cells embedded in a collagen matrix
    and adapted media supplementation, we generate organoids that self-organize into
    highly branched structures displaying a seamless lumen connecting terminal end
    buds, replicating in vivo PDAC architecture. We identify distinct morphogenesis
    phases, each characterized by a unique pattern of cell invasion, matrix deformation,
    protein expression, and respective molecular dependencies. We propose a minimal
    theoretical model of a branching and proliferating tissue, capturing the dynamics
    of the first phases. Observing the interaction of morphogenesis, mechanical environment
    and gene expression in vitro sets a benchmark for the understanding of self-organization
    processes governing complex organoid structure formation processes and branching
    morphogenesis.
acknowledgement: "A.R.B. acknowledges the financial support of the European Research
  Council (ERC) through the funding of the grant Principles of Integrin Mechanics
  and Adhesion (PoINT) and the German Research Foundation (DFG, SFB 1032, project
  ID 201269156). E.H. was supported by the European Union (European Research Council
  Starting Grant 851288). D.S., M.R., and R.R. acknowledge the support by the German
  Research Foundation (DFG, SFB1321 Modeling and Targeting Pancreatic Cancer, Project
  S01, project ID 329628492). C.S. and M.R. acknowledge the support by the German
  Research Foundation (DFG, SFB1321 Modeling and Targeting Pancreatic Cancer, Project
  12, project ID 329628492). M.R. was supported by the German Research Foundation
  (DFG RE 3723/4-1). A.P. and M.R. were supported by the German Cancer Aid (Max-Eder
  Program 111273 and 70114328).\r\nOpen Access funding enabled and organized by Projekt
  DEAL."
article_number: '5219'
article_processing_charge: No
article_type: original
author:
- first_name: S.
  full_name: Randriamanantsoa, S.
  last_name: Randriamanantsoa
- first_name: A.
  full_name: Papargyriou, A.
  last_name: Papargyriou
- first_name: H. C.
  full_name: Maurer, H. C.
  last_name: Maurer
- first_name: K.
  full_name: Peschke, K.
  last_name: Peschke
- first_name: M.
  full_name: Schuster, M.
  last_name: Schuster
- first_name: G.
  full_name: Zecchin, G.
  last_name: Zecchin
- first_name: K.
  full_name: Steiger, K.
  last_name: Steiger
- first_name: R.
  full_name: Öllinger, R.
  last_name: Öllinger
- first_name: D.
  full_name: Saur, D.
  last_name: Saur
- first_name: C.
  full_name: Scheel, C.
  last_name: Scheel
- first_name: R.
  full_name: Rad, R.
  last_name: Rad
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: M.
  full_name: Reichert, M.
  last_name: Reichert
- first_name: A. R.
  full_name: Bausch, A. R.
  last_name: Bausch
citation:
  ama: Randriamanantsoa S, Papargyriou A, Maurer HC, et al. Spatiotemporal dynamics
    of self-organized branching in pancreas-derived organoids. <i>Nature Communications</i>.
    2022;13. doi:<a href="https://doi.org/10.1038/s41467-022-32806-y">10.1038/s41467-022-32806-y</a>
  apa: Randriamanantsoa, S., Papargyriou, A., Maurer, H. C., Peschke, K., Schuster,
    M., Zecchin, G., … Bausch, A. R. (2022). Spatiotemporal dynamics of self-organized
    branching in pancreas-derived organoids. <i>Nature Communications</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41467-022-32806-y">https://doi.org/10.1038/s41467-022-32806-y</a>
  chicago: Randriamanantsoa, S., A. Papargyriou, H. C. Maurer, K. Peschke, M. Schuster,
    G. Zecchin, K. Steiger, et al. “Spatiotemporal Dynamics of Self-Organized Branching
    in Pancreas-Derived Organoids.” <i>Nature Communications</i>. Springer Nature,
    2022. <a href="https://doi.org/10.1038/s41467-022-32806-y">https://doi.org/10.1038/s41467-022-32806-y</a>.
  ieee: S. Randriamanantsoa <i>et al.</i>, “Spatiotemporal dynamics of self-organized
    branching in pancreas-derived organoids,” <i>Nature Communications</i>, vol. 13.
    Springer Nature, 2022.
  ista: Randriamanantsoa S, Papargyriou A, Maurer HC, Peschke K, Schuster M, Zecchin
    G, Steiger K, Öllinger R, Saur D, Scheel C, Rad R, Hannezo EB, Reichert M, Bausch
    AR. 2022. Spatiotemporal dynamics of self-organized branching in pancreas-derived
    organoids. Nature Communications. 13, 5219.
  mla: Randriamanantsoa, S., et al. “Spatiotemporal Dynamics of Self-Organized Branching
    in Pancreas-Derived Organoids.” <i>Nature Communications</i>, vol. 13, 5219, Springer
    Nature, 2022, doi:<a href="https://doi.org/10.1038/s41467-022-32806-y">10.1038/s41467-022-32806-y</a>.
  short: S. Randriamanantsoa, A. Papargyriou, H.C. Maurer, K. Peschke, M. Schuster,
    G. Zecchin, K. Steiger, R. Öllinger, D. Saur, C. Scheel, R. Rad, E.B. Hannezo,
    M. Reichert, A.R. Bausch, Nature Communications 13 (2022).
date_created: 2023-01-16T09:46:53Z
date_published: 2022-09-05T00:00:00Z
date_updated: 2023-08-04T09:25:23Z
day: '05'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1038/s41467-022-32806-y
ec_funded: 1
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keyword:
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language:
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month: '09'
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project:
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publication: Nature Communications
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scopus_import: '1'
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title: Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids
tmp:
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  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
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type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
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...
