[{"language":[{"iso":"eng"}],"ddc":["580"],"oa":1,"external_id":{"isi":["000944921600001"]},"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes","abstract":[{"text":"Cytosine methylation within CG dinucleotides (mCG) can be epigenetically inherited over many generations. Such inheritance is thought to be mediated by a semiconservative mechanism that produces binary present/absent methylation patterns. However, we show here that in Arabidopsis thaliana h1ddm1 mutants, intermediate heterochromatic mCG is stably inherited across many generations and is quantitatively associated with transposon expression. We develop a mathematical model that estimates the rates of semiconservative maintenance failure and de novo methylation at each transposon, demonstrating that mCG can be stably inherited at any level via a dynamic balance of these activities. We find that DRM2 – the core methyltransferase of the RNA-directed DNA methylation pathway – catalyzes most of the heterochromatic de novo mCG, with de novo rates orders of magnitude higher than previously thought, whereas chromomethylases make smaller contributions. Our results demonstrate that stable epigenetic inheritance of mCG in plant heterochromatin is enabled by extensive de novo methylation.","lang":"eng"}],"article_number":"112132","file_date_updated":"2023-05-11T10:41:42Z","oa_version":"Published Version","status":"public","author":[{"first_name":"David B.","full_name":"Lyons, David B.","last_name":"Lyons"},{"full_name":"Briffa, Amy","last_name":"Briffa","first_name":"Amy"},{"last_name":"He","full_name":"He, Shengbo","first_name":"Shengbo"},{"first_name":"Jaemyung","last_name":"Choi","full_name":"Choi, Jaemyung"},{"first_name":"Elizabeth","id":"b8c4f54b-e484-11eb-8fdc-a54df64ef6dd","full_name":"Hollwey, Elizabeth","last_name":"Hollwey"},{"first_name":"Jack","full_name":"Colicchio, Jack","last_name":"Colicchio"},{"first_name":"Ian","full_name":"Anderson, Ian","last_name":"Anderson"},{"id":"e0164712-22ee-11ed-b12a-d80fcdf35958","first_name":"Xiaoqi","last_name":"Feng","full_name":"Feng, Xiaoqi","orcid":"0000-0002-4008-1234"},{"first_name":"Martin","full_name":"Howard, Martin","last_name":"Howard"},{"orcid":"0000-0002-0123-8649","full_name":"Zilberman, Daniel","last_name":"Zilberman","id":"6973db13-dd5f-11ea-814e-b3e5455e9ed1","first_name":"Daniel"}],"year":"2023","ec_funded":1,"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publication_identifier":{"eissn":["2211-1247"]},"day":"28","date_published":"2023-03-28T00:00:00Z","title":"Extensive de novo activity stabilizes epigenetic inheritance of CG methylation in Arabidopsis transposons","publication":"Cell Reports","isi":1,"type":"journal_article","publication_status":"published","scopus_import":"1","quality_controlled":"1","publisher":"Elsevier","has_accepted_license":"1","department":[{"_id":"DaZi"},{"_id":"XiFe"}],"date_created":"2023-02-23T09:17:44Z","date_updated":"2023-11-02T12:23:45Z","intvolume":"        42","month":"03","article_type":"original","citation":{"ista":"Lyons DB, Briffa A, He S, Choi J, Hollwey E, Colicchio J, Anderson I, Feng X, Howard M, Zilberman D. 2023. Extensive de novo activity stabilizes epigenetic inheritance of CG methylation in Arabidopsis transposons. Cell Reports. 42(3), 112132.","apa":"Lyons, D. B., Briffa, A., He, S., Choi, J., Hollwey, E., Colicchio, J., … Zilberman, D. (2023). Extensive de novo activity stabilizes epigenetic inheritance of CG methylation in Arabidopsis transposons. <i>Cell Reports</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.celrep.2023.112132\">https://doi.org/10.1016/j.celrep.2023.112132</a>","ama":"Lyons DB, Briffa A, He S, et al. Extensive de novo activity stabilizes epigenetic inheritance of CG methylation in Arabidopsis transposons. <i>Cell Reports</i>. 2023;42(3). doi:<a href=\"https://doi.org/10.1016/j.celrep.2023.112132\">10.1016/j.celrep.2023.112132</a>","ieee":"D. B. Lyons <i>et al.</i>, “Extensive de novo activity stabilizes epigenetic inheritance of CG methylation in Arabidopsis transposons,” <i>Cell Reports</i>, vol. 42, no. 3. Elsevier, 2023.","short":"D.B. Lyons, A. Briffa, S. He, J. Choi, E. Hollwey, J. Colicchio, I. Anderson, X. Feng, M. Howard, D. Zilberman, Cell Reports 42 (2023).","mla":"Lyons, David B., et al. “Extensive de Novo Activity Stabilizes Epigenetic Inheritance of CG Methylation in Arabidopsis Transposons.” <i>Cell Reports</i>, vol. 42, no. 3, 112132, Elsevier, 2023, doi:<a href=\"https://doi.org/10.1016/j.celrep.2023.112132\">10.1016/j.celrep.2023.112132</a>.","chicago":"Lyons, David B., Amy Briffa, Shengbo He, Jaemyung Choi, Elizabeth Hollwey, Jack Colicchio, Ian Anderson, Xiaoqi Feng, Martin Howard, and Daniel Zilberman. “Extensive de Novo Activity Stabilizes Epigenetic Inheritance of CG Methylation in Arabidopsis Transposons.” <i>Cell Reports</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.celrep.2023.112132\">https://doi.org/10.1016/j.celrep.2023.112132</a>."},"acknowledgement":"The authors would like to thank Jasper Rine for advice and mentorship to D.B.L., Lesley Philips, Timothy Wells, Sophie Able, and Christina Wistrom for support with plant growth, and Bhagyshree Jamge and Frédéric Berger for help with analysis of ddm1 × WT RNA-sequencing data. This work was supported by BBSRC Institute Strategic Program GEN (BB/P013511/1) to X.F., M.H., and D.Z., a European Research Council grant MaintainMeth (725746) to D.Z., and a postdoctoral fellowship from the Helen Hay Whitney Foundation to D.B.L.","issue":"3","_id":"12672","file":[{"date_created":"2023-05-11T10:41:42Z","access_level":"open_access","date_updated":"2023-05-11T10:41:42Z","relation":"main_file","checksum":"6cbc44fdb18bf18834c9e2a5b9c67123","file_id":"12941","success":1,"content_type":"application/pdf","creator":"kschuh","file_size":8401261,"file_name":"2023_CellReports_Lyons.pdf"}],"volume":42,"doi":"10.1016/j.celrep.2023.112132","project":[{"call_identifier":"H2020","grant_number":"725746","name":"Quantitative analysis of DNA methylation maintenance with chromatin","_id":"62935a00-2b32-11ec-9570-eff30fa39068"}]},{"article_number":"e202219314","file_date_updated":"2023-08-16T12:33:31Z","external_id":{"isi":["000956919900001"],"pmid":["36738230"]},"abstract":[{"lang":"eng","text":"Aromatic side chains are important reporters of the plasticity of proteins, and often form important contacts in protein--protein interactions. By studying a pair of structurally homologous cross-β amyloid fibrils, HET-s and HELLF, with a specific isotope-labeling approach and magic-angle-spinning (MAS) NMR, we have characterized the dynamic behavior of Phe and Tyr aromatic rings to show that the hydrophobic amyloid core is rigid, without any sign of \"breathing motions\" over hundreds of milliseconds at least. Aromatic residues exposed at the fibril surface have a rigid ring axis but undergo ring flips, on a variety of time scales from ns to µs. Our approach provides direct insight into hydrophobic-core motions, enabling a better evaluation of the conformational heterogeneity generated from a NMR structural ensemble of such amyloid cross-β architecture."}],"article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["540"],"oa":1,"pmid":1,"language":[{"iso":"eng"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)"},"publication_identifier":{"issn":["1433-7851"],"eissn":["1521-3773"]},"year":"2023","author":[{"id":"36336939-eb97-11eb-a6c2-c83f1214ca79","first_name":"Lea Marie","full_name":"Becker, Lea Marie","last_name":"Becker","orcid":"0000-0002-6401-5151"},{"first_name":"Mélanie","last_name":"Berbon","full_name":"Berbon, Mélanie"},{"first_name":"Alicia","last_name":"Vallet","full_name":"Vallet, Alicia"},{"full_name":"Grelard, Axelle","last_name":"Grelard","first_name":"Axelle"},{"first_name":"Estelle","full_name":"Morvan, Estelle","last_name":"Morvan"},{"full_name":"Bardiaux, Benjamin","last_name":"Bardiaux","first_name":"Benjamin"},{"first_name":"Roman","full_name":"Lichtenecker, Roman","last_name":"Lichtenecker"},{"full_name":"Ernst, Matthias","last_name":"Ernst","first_name":"Matthias"},{"full_name":"Loquet, Antoine","last_name":"Loquet","first_name":"Antoine"},{"orcid":"0000-0002-9350-7606","full_name":"Schanda, Paul","last_name":"Schanda","first_name":"Paul","id":"7B541462-FAF6-11E9-A490-E8DFE5697425"}],"related_material":{"record":[{"relation":"other","status":"public","id":"14861"},{"status":"public","relation":"research_data","id":"12497"}],"link":[{"url":"https://ista.ac.at/en/news/dancing-styles-of-atoms/","description":"News on ISTA website","relation":"press_release"}]},"oa_version":"Published Version","status":"public","has_accepted_license":"1","publication_status":"published","type":"journal_article","quality_controlled":"1","publisher":"Wiley","date_published":"2023-05-01T00:00:00Z","title":"The rigid core and flexible surface of amyloid fibrils probed by Magic‐Angle Spinning NMR of aromatic residues","license":"https://creativecommons.org/licenses/by-nc/4.0/","day":"01","keyword":["General Chemistry","Catalysis"],"isi":1,"publication":"Angewandte Chemie International Edition","volume":62,"file":[{"creator":"dernst","file_name":"2023_AngewChemInt_Becker.pdf","file_size":1422445,"success":1,"file_id":"14072","checksum":"7dd083ed8850faa55c34e411ed390de9","relation":"main_file","date_updated":"2023-08-16T12:33:31Z","access_level":"open_access","date_created":"2023-08-16T12:33:31Z","content_type":"application/pdf"}],"doi":"10.1002/anie.202219314","issue":"19","_id":"12675","article_type":"original","month":"05","acknowledgement":"We thank AlbertA. Smith (Leipzig)for insightful discussions. This work was supported by funding from the European Research Council (StG-2012-311318 to P.S.) and used the platforms of the Grenoble Instruct-ERIC center (ISBG;UMS 3518 CNRS-CEA-UJF-EMBL) within the Grenoble Partnership for Structural Biology(PSB) and facilities and expertiseof the Biophysical and Structural Chemistry platform (BPCS) at IECB,CNRSUAR3033,INSERMUS001 and Bordeaux University.","citation":{"chicago":"Becker, Lea Marie, Mélanie Berbon, Alicia Vallet, Axelle Grelard, Estelle Morvan, Benjamin Bardiaux, Roman Lichtenecker, Matthias Ernst, Antoine Loquet, and Paul Schanda. “The Rigid Core and Flexible Surface of Amyloid Fibrils Probed by Magic‐Angle Spinning NMR of Aromatic Residues.” <i>Angewandte Chemie International Edition</i>. Wiley, 2023. <a href=\"https://doi.org/10.1002/anie.202219314\">https://doi.org/10.1002/anie.202219314</a>.","mla":"Becker, Lea Marie, et al. “The Rigid Core and Flexible Surface of Amyloid Fibrils Probed by Magic‐Angle Spinning NMR of Aromatic Residues.” <i>Angewandte Chemie International Edition</i>, vol. 62, no. 19, e202219314, Wiley, 2023, doi:<a href=\"https://doi.org/10.1002/anie.202219314\">10.1002/anie.202219314</a>.","short":"L.M. Becker, M. Berbon, A. Vallet, A. Grelard, E. Morvan, B. Bardiaux, R. Lichtenecker, M. Ernst, A. Loquet, P. Schanda, Angewandte Chemie International Edition 62 (2023).","ieee":"L. M. Becker <i>et al.</i>, “The rigid core and flexible surface of amyloid fibrils probed by Magic‐Angle Spinning NMR of aromatic residues,” <i>Angewandte Chemie International Edition</i>, vol. 62, no. 19. Wiley, 2023.","ama":"Becker LM, Berbon M, Vallet A, et al. The rigid core and flexible surface of amyloid fibrils probed by Magic‐Angle Spinning NMR of aromatic residues. <i>Angewandte Chemie International Edition</i>. 2023;62(19). doi:<a href=\"https://doi.org/10.1002/anie.202219314\">10.1002/anie.202219314</a>","apa":"Becker, L. M., Berbon, M., Vallet, A., Grelard, A., Morvan, E., Bardiaux, B., … Schanda, P. (2023). The rigid core and flexible surface of amyloid fibrils probed by Magic‐Angle Spinning NMR of aromatic residues. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202219314\">https://doi.org/10.1002/anie.202219314</a>","ista":"Becker LM, Berbon M, Vallet A, Grelard A, Morvan E, Bardiaux B, Lichtenecker R, Ernst M, Loquet A, Schanda P. 2023. The rigid core and flexible surface of amyloid fibrils probed by Magic‐Angle Spinning NMR of aromatic residues. Angewandte Chemie International Edition. 62(19), e202219314."},"date_created":"2023-02-24T10:45:01Z","date_updated":"2024-02-21T12:14:06Z","department":[{"_id":"GradSch"},{"_id":"PaSc"}],"intvolume":"        62"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","abstract":[{"text":"Turn-based stochastic games (aka simple stochastic games) are two-player zero-sum games played on directed graphs with probabilistic transitions. The goal of player-max is to maximize the probability to reach a target state against the adversarial player-min. These games lie in NP ∩ coNP and are among the rare combinatorial problems that belong to this complexity class for which the existence of polynomial-time algorithm is a major open question. While randomized sub-exponential time algorithm exists, all known deterministic algorithms require exponential time in the worst-case. An important open question has been whether faster algorithms can be obtained parametrized by the treewidth of the game graph. Even deterministic sub-exponential time algorithm for constant treewidth turn-based stochastic games has remain elusive. In this work our main result is a deterministic algorithm to solve turn-based stochastic games that, given a game with n states, treewidth at most t, and the bit-complexity of the probabilistic transition function log D, has running time O ((tn2 log D)t log n). In particular, our algorithm is quasi-polynomial time for games with constant or poly-logarithmic treewidth.","lang":"eng"}],"language":[{"iso":"eng"}],"oa":1,"year":"2023","publication_identifier":{"isbn":["9781611977554"]},"ec_funded":1,"status":"public","oa_version":"Published Version","author":[{"id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","first_name":"Krishnendu","orcid":"0000-0002-4561-241X","full_name":"Chatterjee, Krishnendu","last_name":"Chatterjee"},{"orcid":"0000-0002-1712-2165","full_name":"Meggendorfer, Tobias","last_name":"Meggendorfer","first_name":"Tobias","id":"b21b0c15-30a2-11eb-80dc-f13ca25802e1"},{"id":"BD1DF4C4-D767-11E9-B658-BC13E6697425","first_name":"Raimundo J","last_name":"Saona Urmeneta","full_name":"Saona Urmeneta, Raimundo J","orcid":"0000-0001-5103-038X"},{"first_name":"Jakub","id":"130759D2-D7DD-11E9-87D2-DE0DE6697425","full_name":"Svoboda, Jakub","last_name":"Svoboda","orcid":"0000-0002-1419-3267"}],"page":"4590-4605","publisher":"Society for Industrial and Applied Mathematics","type":"conference","publication_status":"published","quality_controlled":"1","publication":"Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms","day":"01","date_published":"2023-02-01T00:00:00Z","title":"Faster algorithm for turn-based stochastic games with bounded treewidth","conference":{"name":"SODA: Symposium on Discrete Algorithms","end_date":"2023-01-25","start_date":"2023-01-22","location":"Florence, Italy"},"_id":"12676","doi":"10.1137/1.9781611977554.ch173","project":[{"grant_number":"863818","name":"Formal Methods for Stochastic Models: Algorithms and Applications","call_identifier":"H2020","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1137/1.9781611977554.ch173"}],"department":[{"_id":"GradSch"},{"_id":"KrCh"}],"date_updated":"2025-07-14T09:09:50Z","date_created":"2023-02-24T12:20:47Z","citation":{"ista":"Chatterjee K, Meggendorfer T, Saona Urmeneta RJ, Svoboda J. 2023. Faster algorithm for turn-based stochastic games with bounded treewidth. Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 4590–4605.","apa":"Chatterjee, K., Meggendorfer, T., Saona Urmeneta, R. J., &#38; Svoboda, J. (2023). Faster algorithm for turn-based stochastic games with bounded treewidth. In <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i> (pp. 4590–4605). Florence, Italy: Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/1.9781611977554.ch173\">https://doi.org/10.1137/1.9781611977554.ch173</a>","ama":"Chatterjee K, Meggendorfer T, Saona Urmeneta RJ, Svoboda J. Faster algorithm for turn-based stochastic games with bounded treewidth. In: <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Society for Industrial and Applied Mathematics; 2023:4590-4605. doi:<a href=\"https://doi.org/10.1137/1.9781611977554.ch173\">10.1137/1.9781611977554.ch173</a>","ieee":"K. Chatterjee, T. Meggendorfer, R. J. Saona Urmeneta, and J. Svoboda, “Faster algorithm for turn-based stochastic games with bounded treewidth,” in <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Florence, Italy, 2023, pp. 4590–4605.","mla":"Chatterjee, Krishnendu, et al. “Faster Algorithm for Turn-Based Stochastic Games with Bounded Treewidth.” <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Society for Industrial and Applied Mathematics, 2023, pp. 4590–605, doi:<a href=\"https://doi.org/10.1137/1.9781611977554.ch173\">10.1137/1.9781611977554.ch173</a>.","short":"K. Chatterjee, T. Meggendorfer, R.J. Saona Urmeneta, J. Svoboda, in:, Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2023, pp. 4590–4605.","chicago":"Chatterjee, Krishnendu, Tobias Meggendorfer, Raimundo J Saona Urmeneta, and Jakub Svoboda. “Faster Algorithm for Turn-Based Stochastic Games with Bounded Treewidth.” In <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 4590–4605. Society for Industrial and Applied Mathematics, 2023. <a href=\"https://doi.org/10.1137/1.9781611977554.ch173\">https://doi.org/10.1137/1.9781611977554.ch173</a>."},"acknowledgement":"This research was partially supported by the ERC CoG 863818 (ForM-SMArt) grant.","month":"02"},{"language":[{"iso":"eng"}],"pmid":1,"oa":1,"ddc":["570"],"abstract":[{"text":"How to generate a brain of correct size and with appropriate cell-type diversity during development is a major question in Neuroscience. In the developing neocortex, radial glial progenitor (RGP) cells are the main neural stem cells that produce cortical excitatory projection neurons, glial cells, and establish the prospective postnatal stem cell niche in the lateral ventricles. RGPs follow a tightly orchestrated developmental program that when disrupted can result in severe cortical malformations such as microcephaly and megalencephaly. The precise cellular and molecular mechanisms instructing faithful RGP lineage progression are however not well understood. This review will summarize recent conceptual advances that contribute to our understanding of the general principles of RGP lineage progression.","lang":"eng"}],"article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"pmid":["36842274"],"isi":["000953497700001"]},"file_date_updated":"2023-08-16T12:29:06Z","article_number":"102695","status":"public","oa_version":"Published Version","author":[{"orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer","full_name":"Hippenmeyer, Simon","first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87"}],"year":"2023","publication_identifier":{"issn":["0959-4388"]},"ec_funded":1,"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"isi":1,"publication":"Current Opinion in Neurobiology","title":"Principles of neural stem cell lineage progression: Insights from developing cerebral cortex","date_published":"2023-04-01T00:00:00Z","keyword":["General Neuroscience"],"day":"01","publisher":"Elsevier","type":"journal_article","publication_status":"published","quality_controlled":"1","scopus_import":"1","has_accepted_license":"1","intvolume":"        79","date_created":"2023-02-26T12:24:21Z","date_updated":"2023-08-16T12:30:25Z","department":[{"_id":"SiHi"}],"acknowledgement":"I wish to thank all current and past members of the Hippenmeyer laboratory at ISTA for exciting discussions on the subject of this review. I apologize to colleagues whose work I could not cite and/or discuss in the frame of the available space. Work in the Hippenmeyer laboratory on the\r\ndiscussed topic is supported by ISTA institutional funds, FWF SFB F78 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Programme (grant agree-ment no. 725780 LinPro) to SH.","citation":{"chicago":"Hippenmeyer, Simon. “Principles of Neural Stem Cell Lineage Progression: Insights from Developing Cerebral Cortex.” <i>Current Opinion in Neurobiology</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.conb.2023.102695\">https://doi.org/10.1016/j.conb.2023.102695</a>.","short":"S. Hippenmeyer, Current Opinion in Neurobiology 79 (2023).","mla":"Hippenmeyer, Simon. “Principles of Neural Stem Cell Lineage Progression: Insights from Developing Cerebral Cortex.” <i>Current Opinion in Neurobiology</i>, vol. 79, no. 4, 102695, Elsevier, 2023, doi:<a href=\"https://doi.org/10.1016/j.conb.2023.102695\">10.1016/j.conb.2023.102695</a>.","ieee":"S. Hippenmeyer, “Principles of neural stem cell lineage progression: Insights from developing cerebral cortex,” <i>Current Opinion in Neurobiology</i>, vol. 79, no. 4. Elsevier, 2023.","ama":"Hippenmeyer S. Principles of neural stem cell lineage progression: Insights from developing cerebral cortex. <i>Current Opinion in Neurobiology</i>. 2023;79(4). doi:<a href=\"https://doi.org/10.1016/j.conb.2023.102695\">10.1016/j.conb.2023.102695</a>","apa":"Hippenmeyer, S. (2023). Principles of neural stem cell lineage progression: Insights from developing cerebral cortex. <i>Current Opinion in Neurobiology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.conb.2023.102695\">https://doi.org/10.1016/j.conb.2023.102695</a>","ista":"Hippenmeyer S. 2023. Principles of neural stem cell lineage progression: Insights from developing cerebral cortex. Current Opinion in Neurobiology. 79(4), 102695."},"article_type":"review","month":"04","_id":"12679","issue":"4","project":[{"_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","name":"Molecular Mechanisms of Neural Stem Cell Lineage Progression","grant_number":"F07805"},{"_id":"260018B0-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"725780","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development"}],"doi":"10.1016/j.conb.2023.102695","volume":79,"file":[{"content_type":"application/pdf","success":1,"access_level":"open_access","relation":"main_file","date_updated":"2023-08-16T12:29:06Z","date_created":"2023-08-16T12:29:06Z","file_id":"14071","checksum":"4d11c4ca87e6cbc4d2ac46d3225ea615","file_size":1787894,"file_name":"2023_CurrentOpinionNeurobio_Hippenmeyer.pdf","creator":"dernst"}]},{"doi":"10.1016/j.disc.2023.113363","volume":346,"main_file_link":[{"open_access":"1","url":" https://doi.org/10.48550/arXiv.2201.10892"}],"_id":"12680","issue":"6","citation":{"mla":"Ivanov, Grigory, and Seyda Köse. “Erdős-Ko-Rado and Hilton-Milner Theorems for Two-Forms.” <i>Discrete Mathematics</i>, vol. 346, no. 6, 113363, Elsevier, 2023, doi:<a href=\"https://doi.org/10.1016/j.disc.2023.113363\">10.1016/j.disc.2023.113363</a>.","short":"G. Ivanov, S. Köse, Discrete Mathematics 346 (2023).","ieee":"G. Ivanov and S. Köse, “Erdős-Ko-Rado and Hilton-Milner theorems for two-forms,” <i>Discrete Mathematics</i>, vol. 346, no. 6. Elsevier, 2023.","chicago":"Ivanov, Grigory, and Seyda Köse. “Erdős-Ko-Rado and Hilton-Milner Theorems for Two-Forms.” <i>Discrete Mathematics</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.disc.2023.113363\">https://doi.org/10.1016/j.disc.2023.113363</a>.","ista":"Ivanov G, Köse S. 2023. Erdős-Ko-Rado and Hilton-Milner theorems for two-forms. Discrete Mathematics. 346(6), 113363.","ama":"Ivanov G, Köse S. Erdős-Ko-Rado and Hilton-Milner theorems for two-forms. <i>Discrete Mathematics</i>. 2023;346(6). doi:<a href=\"https://doi.org/10.1016/j.disc.2023.113363\">10.1016/j.disc.2023.113363</a>","apa":"Ivanov, G., &#38; Köse, S. (2023). Erdős-Ko-Rado and Hilton-Milner theorems for two-forms. <i>Discrete Mathematics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.disc.2023.113363\">https://doi.org/10.1016/j.disc.2023.113363</a>"},"month":"06","article_type":"letter_note","intvolume":"       346","department":[{"_id":"UlWa"},{"_id":"GradSch"}],"date_updated":"2023-10-04T11:54:57Z","date_created":"2023-02-26T23:01:00Z","arxiv":1,"publisher":"Elsevier","type":"journal_article","publication_status":"published","quality_controlled":"1","scopus_import":"1","publication":"Discrete Mathematics","day":"01","title":"Erdős-Ko-Rado and Hilton-Milner theorems for two-forms","date_published":"2023-06-01T00:00:00Z","publication_identifier":{"issn":["0012-365X"]},"year":"2023","related_material":{"record":[{"id":"13331","status":"public","relation":"dissertation_contains"}]},"author":[{"full_name":"Ivanov, Grigory","last_name":"Ivanov","id":"87744F66-5C6F-11EA-AFE0-D16B3DDC885E","first_name":"Grigory"},{"last_name":"Köse","full_name":"Köse, Seyda","id":"8ba3170d-dc85-11ea-9058-c4251c96a6eb","first_name":"Seyda"}],"status":"public","oa_version":"Preprint","article_number":"113363","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"The celebrated Erdős–Ko–Rado theorem about the maximal size of an intersecting family of r-element subsets of  was extended to the setting of exterior algebra in [5, Theorem 2.3] and in [6, Theorem 1.4]. However, the equality case has not been settled yet. In this short note, we show that the extension of the Erdős–Ko–Rado theorem and the characterization of the equality case therein, as well as those of the Hilton–Milner theorem to the setting of exterior algebra in the simplest non-trivial case of two-forms follow from a folklore puzzle about possible arrangements of an intersecting family of lines.","lang":"eng"}],"article_processing_charge":"No","external_id":{"arxiv":["2201.10892"]},"oa":1,"language":[{"iso":"eng"}]},{"oa":1,"ddc":["530"],"language":[{"iso":"eng"}],"file_date_updated":"2023-02-27T09:23:02Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","abstract":[{"lang":"eng","text":"The dissolution of minute concentration of polymers in wall-bounded flows is well-known for its unparalleled ability to reduce turbulent friction drag. Another phenomenon, elasto-inertial turbulence (EIT), has been far less studied even though elastic instabilities have already been observed in dilute polymer solutions before the discovery of polymer drag reduction. EIT is a chaotic state driven by polymer dynamics that is observed across many orders of magnitude in Reynolds number. It involves energy transfer from small elastic scales to large flow scales. The investigation of the mechanisms of EIT offers the possibility to better understand other complex phenomena such as elastic turbulence and maximum drag reduction. In this review, we survey recent research efforts that are advancing the understanding of the dynamics of EIT. We highlight the fundamental differences between EIT and Newtonian/inertial turbulence from the perspective of experiments, numerical simulations, instabilities, and coherent structures. Finally, we discuss the possible links between EIT and elastic turbulence and polymer drag reduction, as well as the remaining challenges in unraveling the self-sustaining mechanism of EIT."}],"article_processing_charge":"No","external_id":{"isi":["000915418100026"]},"author":[{"first_name":"Yves","last_name":"Dubief","full_name":"Dubief, Yves"},{"first_name":"Vincent E.","full_name":"Terrapon, Vincent E.","last_name":"Terrapon"},{"id":"3A374330-F248-11E8-B48F-1D18A9856A87","first_name":"Björn","orcid":"0000-0003-2057-2754","last_name":"Hof","full_name":"Hof, Björn"}],"page":"675-705","status":"public","oa_version":"Published Version","publication_identifier":{"issn":["0066-4189"],"eissn":["1545-4479"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2023","publication":"Annual Review of Fluid Mechanics","isi":1,"day":"19","date_published":"2023-01-19T00:00:00Z","title":"Elasto-inertial turbulence","has_accepted_license":"1","publisher":"Annual Reviews","scopus_import":"1","quality_controlled":"1","publication_status":"published","type":"journal_article","citation":{"ista":"Dubief Y, Terrapon VE, Hof B. 2023. Elasto-inertial turbulence. Annual Review of Fluid Mechanics. 55(1), 675–705.","ama":"Dubief Y, Terrapon VE, Hof B. Elasto-inertial turbulence. <i>Annual Review of Fluid Mechanics</i>. 2023;55(1):675-705. doi:<a href=\"https://doi.org/10.1146/annurev-fluid-032822-025933\">10.1146/annurev-fluid-032822-025933</a>","apa":"Dubief, Y., Terrapon, V. E., &#38; Hof, B. (2023). Elasto-inertial turbulence. <i>Annual Review of Fluid Mechanics</i>. Annual Reviews. <a href=\"https://doi.org/10.1146/annurev-fluid-032822-025933\">https://doi.org/10.1146/annurev-fluid-032822-025933</a>","mla":"Dubief, Yves, et al. “Elasto-Inertial Turbulence.” <i>Annual Review of Fluid Mechanics</i>, vol. 55, no. 1, Annual Reviews, 2023, pp. 675–705, doi:<a href=\"https://doi.org/10.1146/annurev-fluid-032822-025933\">10.1146/annurev-fluid-032822-025933</a>.","short":"Y. Dubief, V.E. Terrapon, B. Hof, Annual Review of Fluid Mechanics 55 (2023) 675–705.","ieee":"Y. Dubief, V. E. Terrapon, and B. Hof, “Elasto-inertial turbulence,” <i>Annual Review of Fluid Mechanics</i>, vol. 55, no. 1. Annual Reviews, pp. 675–705, 2023.","chicago":"Dubief, Yves, Vincent E. Terrapon, and Björn Hof. “Elasto-Inertial Turbulence.” <i>Annual Review of Fluid Mechanics</i>. Annual Reviews, 2023. <a href=\"https://doi.org/10.1146/annurev-fluid-032822-025933\">https://doi.org/10.1146/annurev-fluid-032822-025933</a>."},"acknowledgement":"Part of the material presented here is based upon work supported by the National Science Foundation CBET (Chemical, Bioengineering, Environmental and Transport Systems) award 1805636 (to Y.D.), the Binational Science Foundation award 2016145 (to Y.D. and Victor Steinberg), a FRIA (Fund for Research Training in Industry and Agriculture) grant of the Belgian F.R.S.-FNRS (National Fund for Scientific Research) (to V.E.T.), the Marie Curie FP7 Career Integration grant PCIG10-GA-2011-304073 (to V.E.T.), and the Fonds spéciaux pour la recherche grant C-13/19 of the University of Liege (to V.E.T.). Computational resources have been provided by the Consortium des Équipements de Calcul Intensif (CECI) funded by the Belgian F.R.S.-FNRS, the Vermont Advanced Computing Center (VACC), the Partnership for Advanced Computing in Europe (PRACE), and the Tier-1 supercomputer of the Fédération Wallonie-Bruxelles funded by the Walloon Region (grant agreement 117545).","month":"01","article_type":"original","intvolume":"        55","department":[{"_id":"BjHo"}],"date_created":"2023-02-26T23:01:01Z","date_updated":"2023-08-01T13:19:47Z","doi":"10.1146/annurev-fluid-032822-025933","file":[{"file_id":"12690","checksum":"2666aa3af2a25252d35eb8681d3edff7","date_created":"2023-02-27T09:23:02Z","relation":"main_file","access_level":"open_access","date_updated":"2023-02-27T09:23:02Z","success":1,"content_type":"application/pdf","creator":"dernst","file_size":4036706,"file_name":"2023_AnnReviewFluidMech_Dubief.pdf"}],"volume":55,"_id":"12681","issue":"1"},{"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_processing_charge":"No","abstract":[{"text":"Since the seminal studies by Osborne Reynolds in the nineteenth century, pipe flow has served as a primary prototype for investigating the transition to turbulence in wall-bounded flows. Despite the apparent simplicity of this flow, various facets of this problem have occupied researchers for more than a century. Here we review insights from three distinct perspectives: (a) stability and susceptibility of laminar flow, (b) phase transition and spatiotemporal dynamics, and (c) dynamical systems analysis of the Navier—Stokes equations. We show how these perspectives have led to a profound understanding of the onset of turbulence in pipe flow. Outstanding open points, applications to flows of complex fluids, and similarities with other wall-bounded flows are discussed.","lang":"eng"}],"external_id":{"isi":["000915418100023"]},"file_date_updated":"2023-02-27T09:35:52Z","language":[{"iso":"eng"}],"oa":1,"ddc":["530"],"year":"2023","publication_identifier":{"issn":["0066-4189"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"status":"public","oa_version":"Published Version","author":[{"first_name":"Marc","last_name":"Avila","full_name":"Avila, Marc"},{"last_name":"Barkley","full_name":"Barkley, Dwight","first_name":"Dwight"},{"first_name":"Björn","id":"3A374330-F248-11E8-B48F-1D18A9856A87","last_name":"Hof","full_name":"Hof, Björn","orcid":"0000-0003-2057-2754"}],"page":"575-602","publisher":"Annual Reviews","publication_status":"published","scopus_import":"1","type":"journal_article","quality_controlled":"1","has_accepted_license":"1","publication":"Annual Review of Fluid Mechanics","isi":1,"day":"19","title":"Transition to turbulence in pipe flow","date_published":"2023-01-19T00:00:00Z","_id":"12682","doi":"10.1146/annurev-fluid-120720-025957","project":[{"name":"Revisiting the Turbulence Problem Using Statistical Mechanics: Experimental Studies on Transitional and Turbulent Flows","grant_number":"662960","_id":"238598C6-32DE-11EA-91FC-C7463DDC885E"}],"file":[{"content_type":"application/pdf","success":1,"date_created":"2023-02-27T09:35:52Z","date_updated":"2023-02-27T09:35:52Z","access_level":"open_access","relation":"main_file","file_id":"12691","checksum":"f99ef30f76cabc9e5e1946b380c16db4","file_name":"2023_AnnReviewFluidMech_Avila.pdf","file_size":4769537,"creator":"dernst"}],"volume":55,"intvolume":"        55","department":[{"_id":"BjHo"}],"date_updated":"2023-08-01T13:20:30Z","date_created":"2023-02-26T23:01:01Z","citation":{"chicago":"Avila, Marc, Dwight Barkley, and Björn Hof. “Transition to Turbulence in Pipe Flow.” <i>Annual Review of Fluid Mechanics</i>. Annual Reviews, 2023. <a href=\"https://doi.org/10.1146/annurev-fluid-120720-025957\">https://doi.org/10.1146/annurev-fluid-120720-025957</a>.","ieee":"M. Avila, D. Barkley, and B. Hof, “Transition to turbulence in pipe flow,” <i>Annual Review of Fluid Mechanics</i>, vol. 55. Annual Reviews, pp. 575–602, 2023.","short":"M. Avila, D. Barkley, B. Hof, Annual Review of Fluid Mechanics 55 (2023) 575–602.","mla":"Avila, Marc, et al. “Transition to Turbulence in Pipe Flow.” <i>Annual Review of Fluid Mechanics</i>, vol. 55, Annual Reviews, 2023, pp. 575–602, doi:<a href=\"https://doi.org/10.1146/annurev-fluid-120720-025957\">10.1146/annurev-fluid-120720-025957</a>.","apa":"Avila, M., Barkley, D., &#38; Hof, B. (2023). Transition to turbulence in pipe flow. <i>Annual Review of Fluid Mechanics</i>. Annual Reviews. <a href=\"https://doi.org/10.1146/annurev-fluid-120720-025957\">https://doi.org/10.1146/annurev-fluid-120720-025957</a>","ama":"Avila M, Barkley D, Hof B. Transition to turbulence in pipe flow. <i>Annual Review of Fluid Mechanics</i>. 2023;55:575-602. doi:<a href=\"https://doi.org/10.1146/annurev-fluid-120720-025957\">10.1146/annurev-fluid-120720-025957</a>","ista":"Avila M, Barkley D, Hof B. 2023. Transition to turbulence in pipe flow. Annual Review of Fluid Mechanics. 55, 575–602."},"acknowledgement":"The authors are very grateful to Laurette Tuckerman for her helpful comments. This work was supported by grants from the Simons Foundation (grant numbers 662985, D.B., and 662960, B.H.) and the Priority Programme “SPP 1881: Turbulent Superstructures” of the Deutsche Forschungsgemeinschaft (grant number AV120/3-2 to M.A.).","article_type":"original","month":"01"},{"publication":"Electronic Communications in Probability","isi":1,"day":"08","title":"Dynamics of a rank-one perturbation of a Hermitian matrix","date_published":"2023-02-08T00:00:00Z","arxiv":1,"has_accepted_license":"1","publisher":"Institute of Mathematical Statistics","publication_status":"published","type":"journal_article","quality_controlled":"1","scopus_import":"1","citation":{"ieee":"G. Dubach and L. Erdös, “Dynamics of a rank-one perturbation of a Hermitian matrix,” <i>Electronic Communications in Probability</i>, vol. 28. Institute of Mathematical Statistics, pp. 1–13, 2023.","mla":"Dubach, Guillaume, and László Erdös. “Dynamics of a Rank-One Perturbation of a Hermitian Matrix.” <i>Electronic Communications in Probability</i>, vol. 28, Institute of Mathematical Statistics, 2023, pp. 1–13, doi:<a href=\"https://doi.org/10.1214/23-ECP516\">10.1214/23-ECP516</a>.","short":"G. Dubach, L. Erdös, Electronic Communications in Probability 28 (2023) 1–13.","chicago":"Dubach, Guillaume, and László Erdös. “Dynamics of a Rank-One Perturbation of a Hermitian Matrix.” <i>Electronic Communications in Probability</i>. Institute of Mathematical Statistics, 2023. <a href=\"https://doi.org/10.1214/23-ECP516\">https://doi.org/10.1214/23-ECP516</a>.","ista":"Dubach G, Erdös L. 2023. Dynamics of a rank-one perturbation of a Hermitian matrix. Electronic Communications in Probability. 28, 1–13.","apa":"Dubach, G., &#38; Erdös, L. (2023). Dynamics of a rank-one perturbation of a Hermitian matrix. <i>Electronic Communications in Probability</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/23-ECP516\">https://doi.org/10.1214/23-ECP516</a>","ama":"Dubach G, Erdös L. Dynamics of a rank-one perturbation of a Hermitian matrix. <i>Electronic Communications in Probability</i>. 2023;28:1-13. doi:<a href=\"https://doi.org/10.1214/23-ECP516\">10.1214/23-ECP516</a>"},"acknowledgement":"G. Dubach gratefully acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 754411. L. Erdős is supported by ERC Advanced Grant “RMTBeyond” No. 101020331.","month":"02","article_type":"original","intvolume":"        28","department":[{"_id":"LaEr"}],"date_updated":"2023-10-17T12:48:10Z","date_created":"2023-02-26T23:01:01Z","doi":"10.1214/23-ECP516","project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"},{"call_identifier":"H2020","grant_number":"101020331","name":"Random matrices beyond Wigner-Dyson-Mehta","_id":"62796744-2b32-11ec-9570-940b20777f1d"}],"file":[{"content_type":"application/pdf","relation":"main_file","date_created":"2023-02-27T09:43:27Z","access_level":"open_access","date_updated":"2023-02-27T09:43:27Z","checksum":"a1c6f0a3e33688fd71309c86a9aad86e","file_id":"12692","success":1,"file_name":"2023_ElectCommProbability_Dubach.pdf","file_size":479105,"creator":"dernst"}],"volume":28,"_id":"12683","oa":1,"ddc":["510"],"language":[{"iso":"eng"}],"file_date_updated":"2023-02-27T09:43:27Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"We study the eigenvalue trajectories of a time dependent matrix Gt=H+itvv∗ for t≥0, where H is an N×N Hermitian random matrix and v is a unit vector. In particular, we establish that with high probability, an outlier can be distinguished at all times t>1+N−1/3+ϵ, for any ϵ>0. The study of this natural process combines elements of Hermitian and non-Hermitian analysis, and illustrates some aspects of the intrinsic instability of (even weakly) non-Hermitian matrices.","lang":"eng"}],"article_processing_charge":"No","external_id":{"isi":["000950650200005"],"arxiv":["2108.13694"]},"author":[{"last_name":"Dubach","full_name":"Dubach, Guillaume","orcid":"0000-0001-6892-8137","first_name":"Guillaume","id":"D5C6A458-10C4-11EA-ABF4-A4B43DDC885E"},{"full_name":"Erdös, László","last_name":"Erdös","orcid":"0000-0001-5366-9603","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87"}],"page":"1-13","status":"public","oa_version":"Published Version","publication_identifier":{"eissn":["1083-589X"]},"ec_funded":1,"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2023"},{"_id":"12693","year":"2023","doi":"10.15479/AT:ISTA:12693","file":[{"success":1,"date_updated":"2023-02-28T06:34:08Z","relation":"main_file","date_created":"2023-02-28T06:34:08Z","access_level":"open_access","checksum":"c1565d655ca05601acfd84e0d12b8563","file_id":"12694","content_type":"application/pdf","creator":"scremer","file_name":"Metzler_ReadMe.pdf","file_size":77070},{"content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","success":1,"access_level":"open_access","date_updated":"2023-02-28T06:34:12Z","relation":"main_file","date_created":"2023-02-28T06:34:12Z","checksum":"75c4c4948563d6261cb7548f80d909f1","file_id":"12695","file_name":"Metzler_RepositoryData.xlsx","file_size":88001,"creator":"scremer"}],"contributor":[{"contributor_type":"data_collector","last_name":"Metzler","id":"48204546-F248-11E8-B48F-1D18A9856A87","first_name":"Sina"},{"first_name":"Jessica","id":"21516227-15aa-11ec-9fb2-c6e8ffc155d3","last_name":"Kirchner","contributor_type":"data_collector"},{"id":"406F989C-F248-11E8-B48F-1D18A9856A87","first_name":"Anna V","contributor_type":"data_collector","last_name":"Grasse"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)"},"status":"public","department":[{"_id":"SyCr"}],"oa_version":"Published Version","date_created":"2023-02-28T06:38:37Z","date_updated":"2023-12-13T11:13:13Z","citation":{"mla":"Cremer, Sylvia. <i>Source Data for Metzler et Al, 2023: Trade-Offs between Immunity and Competitive Ability in Fighting Ant Males </i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12693\">10.15479/AT:ISTA:12693</a>.","short":"S. Cremer, (2023).","ieee":"S. Cremer, “Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males .” Institute of Science and Technology Austria, 2023.","chicago":"Cremer, Sylvia. “Source Data for Metzler et Al, 2023: Trade-Offs between Immunity and Competitive Ability in Fighting Ant Males .” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/AT:ISTA:12693\">https://doi.org/10.15479/AT:ISTA:12693</a>.","ista":"Cremer S. 2023. Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males , Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:12693\">10.15479/AT:ISTA:12693</a>.","ama":"Cremer S. Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males . 2023. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12693\">10.15479/AT:ISTA:12693</a>","apa":"Cremer, S. (2023). Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males . Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:12693\">https://doi.org/10.15479/AT:ISTA:12693</a>"},"related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"12696"}]},"author":[{"full_name":"Cremer, Sylvia","last_name":"Cremer","orcid":"0000-0002-2193-3868","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","first_name":"Sylvia"}],"month":"02","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","abstract":[{"lang":"eng","text":"See Readme File for further information."}],"type":"research_data","file_date_updated":"2023-02-28T06:34:12Z","has_accepted_license":"1","day":"28","title":"Source data for Metzler et al, 2023: Trade-offs between immunity and competitive ability in fighting ant males ","date_published":"2023-02-28T00:00:00Z","oa":1,"ddc":["570"]},{"ddc":["570"],"oa":1,"pmid":1,"language":[{"iso":"eng"}],"article_number":"37","file_date_updated":"2023-08-14T07:51:47Z","external_id":{"isi":["001042643600002"],"pmid":["37550612"]},"abstract":[{"text":"Background: Fighting disease while fighting rivals exposes males to constraints and tradeoffs during male-male competition. We here tested how both the stage and intensity of infection with the fungal pathogen Metarhizium robertsii interfered with fighting success in Cardiocondyla obscurior ant males. Males of this species have evolved long lifespans during which they can gain many matings with the young queens of the colony, if successful in male-male competition. Since male fights occur inside the colony, the outcome of male-male competition can further be biased by interference of the colony’s worker force.\r\nResults: We found that severe, but not yet mild, infection strongly impaired male fighting success. In late-stage infection, this could be attributed to worker aggression directed towards the infected rather than the healthy male and an already very high male morbidity even in the absence of fighting. Shortly after pathogen exposure, however, male mortality was particularly increased during combat. Since these males mounted a strong immune response, their reduced fighting success suggests a trade-off between immune investment and competitive ability already early in the infection. Even if the males themselves showed no difference in the number of attacks they raised against their healthy rivals across infection stages and levels, severely infected males were thus losing in male-male competition from an early stage of infection on.\r\nConclusions: Males of the ant C. obscurior have evolved high immune investment, triggering an effective immune response very fast after fungal exposure. This allows them to cope with mild pathogen exposures without cost to their success in male-male competition, and hence to gain multiple mating opportunities with the emerging virgin queens of the colony. Under severe infection, however, they are weak fighters and rarely survive a combat already at early infection when raising an immune response, as well as at progressed infection, when they are morbid and preferentially targeted by worker aggression. Workers thereby remove males that pose a future disease threat by biasing male-male competition. Our study thus revealed a novel social immunity mechanism how social insect workers protect the colony against disease risk.","lang":"eng"}],"article_processing_charge":"Yes","acknowledged_ssus":[{"_id":"LifeSc"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"orcid":"0000-0002-9547-2494","last_name":"Metzler","full_name":"Metzler, Sina","first_name":"Sina","id":"48204546-F248-11E8-B48F-1D18A9856A87"},{"id":"21516227-15aa-11ec-9fb2-c6e8ffc155d3","first_name":"Jessica","last_name":"Kirchner","full_name":"Kirchner, Jessica"},{"first_name":"Anna V","id":"406F989C-F248-11E8-B48F-1D18A9856A87","last_name":"Grasse","full_name":"Grasse, Anna V"},{"first_name":"Sylvia","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","last_name":"Cremer","full_name":"Cremer, Sylvia","orcid":"0000-0002-2193-3868"}],"related_material":{"record":[{"status":"public","relation":"research_data","id":"12693"}]},"oa_version":"Published Version","status":"public","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ec_funded":1,"publication_identifier":{"issn":["2730-7182"]},"year":"2023","title":"Trade-offs between immunity and competitive ability in fighting ant males","date_published":"2023-08-07T00:00:00Z","day":"07","isi":1,"publication":"BMC Ecology and Evolution","has_accepted_license":"1","quality_controlled":"1","type":"journal_article","scopus_import":"1","publication_status":"published","publisher":"Springer Nature","month":"08","article_type":"original","acknowledgement":"We are thankful to Mike Bidochka for the fungal strain, Lukas Schrader for sharing the C. obscurior genome data for primer development, the Lab Support Facility of ISTA for general laboratory support and help with the permit approval procedures, and the Finca El Quinto for letting us collect ants on their property. We thank the Social Immunity Team at ISTA for help with ant collection and experimental help, in particular Elina Hanhimäki and Marta Gorecka for behavioural observation, and Elisabeth Naderlinger for spore load PCRs. We further thank the Social Immunity Team and Jürgen Heinze for continued discussion and comments on the manuscript.\r\nOpen access funding provided by Institute of Science and Technology Austria (ISTA). This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 771402 to SC). ","citation":{"ieee":"S. Metzler, J. Kirchner, A. V. Grasse, and S. Cremer, “Trade-offs between immunity and competitive ability in fighting ant males,” <i>BMC Ecology and Evolution</i>, vol. 23. Springer Nature, 2023.","short":"S. Metzler, J. Kirchner, A.V. Grasse, S. Cremer, BMC Ecology and Evolution 23 (2023).","mla":"Metzler, Sina, et al. “Trade-Offs between Immunity and Competitive Ability in Fighting Ant Males.” <i>BMC Ecology and Evolution</i>, vol. 23, 37, Springer Nature, 2023, doi:<a href=\"https://doi.org/10.1186/s12862-023-02137-7\">10.1186/s12862-023-02137-7</a>.","chicago":"Metzler, Sina, Jessica Kirchner, Anna V Grasse, and Sylvia Cremer. “Trade-Offs between Immunity and Competitive Ability in Fighting Ant Males.” <i>BMC Ecology and Evolution</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1186/s12862-023-02137-7\">https://doi.org/10.1186/s12862-023-02137-7</a>.","ista":"Metzler S, Kirchner J, Grasse AV, Cremer S. 2023. Trade-offs between immunity and competitive ability in fighting ant males. BMC Ecology and Evolution. 23, 37.","apa":"Metzler, S., Kirchner, J., Grasse, A. V., &#38; Cremer, S. (2023). Trade-offs between immunity and competitive ability in fighting ant males. <i>BMC Ecology and Evolution</i>. Springer Nature. <a href=\"https://doi.org/10.1186/s12862-023-02137-7\">https://doi.org/10.1186/s12862-023-02137-7</a>","ama":"Metzler S, Kirchner J, Grasse AV, Cremer S. Trade-offs between immunity and competitive ability in fighting ant males. <i>BMC Ecology and Evolution</i>. 2023;23. doi:<a href=\"https://doi.org/10.1186/s12862-023-02137-7\">10.1186/s12862-023-02137-7</a>"},"date_created":"2023-02-28T07:38:17Z","date_updated":"2023-12-13T11:13:14Z","department":[{"_id":"SyCr"}],"intvolume":"        23","volume":23,"file":[{"access_level":"open_access","relation":"main_file","date_updated":"2023-08-14T07:51:47Z","date_created":"2023-08-14T07:51:47Z","file_id":"14048","checksum":"95966dc7d242d2c85bdd4fe14233dbd8","success":1,"content_type":"application/pdf","creator":"dernst","file_size":2004276,"file_name":"2023_BMCEcology_Metzler.pdf"}],"project":[{"_id":"2649B4DE-B435-11E9-9278-68D0E5697425","grant_number":"771402","name":"Epidemics in ant societies on a chip","call_identifier":"H2020"}],"doi":"10.1186/s12862-023-02137-7","_id":"12696"},{"article_number":"098202","file_date_updated":"2023-02-28T12:37:54Z","external_id":{"arxiv":["2211.02488"],"isi":["000946178200008"]},"article_processing_charge":"No","abstract":[{"text":"Models for same-material contact electrification in granular media often rely on a local charge-driving parameter whose spatial variations lead to a stochastic origin for charge exchange. Measuring the charge transfer from individual granular spheres after contacts with substrates of the same material, we find instead a “global” charging behavior, coherent over the sample’s whole surface. Cleaning and baking samples fully resets charging magnitude and direction, which indicates the underlying global parameter is not intrinsic to the material, but acquired from its history. Charging behavior is randomly and irreversibly affected by changes in relative humidity, hinting at a mechanism where adsorbates, in particular, water, are fundamental to the charge-transfer process.","lang":"eng"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","ddc":["530","537"],"oa":1,"language":[{"iso":"eng"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ec_funded":1,"publication_identifier":{"eissn":["1079-7114"],"issn":["0031-9007"]},"year":"2023","author":[{"first_name":"Galien M","id":"0C5FDA4A-9CF6-11E9-8939-FF05E6697425","full_name":"Grosjean, Galien M","last_name":"Grosjean","orcid":"0000-0001-5154-417X"},{"orcid":"0000-0002-2299-3176","last_name":"Waitukaitis","full_name":"Waitukaitis, Scott R","first_name":"Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87"}],"related_material":{"record":[{"id":"8101","status":"public","relation":"research_paper"}]},"oa_version":"Preprint","status":"public","has_accepted_license":"1","arxiv":1,"type":"journal_article","publication_status":"published","quality_controlled":"1","publisher":"American Physical Society","title":"Single-collision statistics reveal a global mechanism driven by sample history for contact electrification in granular media","date_published":"2023-03-03T00:00:00Z","keyword":["General Physics","Electrostatics","Triboelectricity","Soft Matter","Acoustic Levitation","Granular Materials"],"day":"03","isi":1,"publication":"Physical Review Letters","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2211.02488"}],"volume":130,"file":[{"content_type":"application/pdf","success":1,"relation":"main_file","date_created":"2023-02-28T12:20:27Z","access_level":"open_access","date_updated":"2023-02-28T12:20:27Z","checksum":"c4f2f6eea0408811f8f4898e15890355","file_id":"12698","file_size":2301864,"file_name":"Main_Preprint.pdf","creator":"ggrosjea"},{"creator":"ggrosjea","file_size":1138625,"file_name":"Suppl_info.pdf","access_level":"open_access","date_created":"2023-02-28T12:20:55Z","relation":"main_file","date_updated":"2023-02-28T12:20:55Z","checksum":"6af6ed6c97a977f923de4162294b43c4","file_id":"12699","success":1,"content_type":"application/pdf"},{"file_size":793449,"file_name":"Suppl_vid1.mp4","creator":"ggrosjea","content_type":"video/mp4","success":1,"relation":"main_file","access_level":"open_access","date_created":"2023-02-28T12:37:54Z","date_updated":"2023-02-28T12:37:54Z","file_id":"12700","checksum":"3f20365fb9515bdba3a111d912c8d8b4"},{"file_size":455925,"file_name":"Suppl_vid2.mp4","creator":"ggrosjea","content_type":"video/mp4","file_id":"12701","checksum":"90cecacbe0e2f9dea11f91a4ba20c32e","relation":"main_file","date_created":"2023-02-28T12:37:54Z","date_updated":"2023-02-28T12:37:54Z","access_level":"open_access","success":1}],"project":[{"call_identifier":"H2020","name":"Tribocharge: a multi-scale approach to an enduring problem in physics","grant_number":"949120","_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020"}],"doi":"10.1103/physrevlett.130.098202","issue":"9","_id":"12697","article_type":"original","month":"03","acknowledgement":"We would like to thank Troy Shinbrot, Victor Lee and Daniele Foresti for helpful discussions. This project has received funding from the European Research Council Grant Agreement No. 949120 and from the the Marie Sk lodowska-Curie Grant Agreement No. 754411 under\r\nthe European Union’s Horizon 2020 research and innovation program.","citation":{"apa":"Grosjean, G. M., &#38; Waitukaitis, S. R. (2023). Single-collision statistics reveal a global mechanism driven by sample history for contact electrification in granular media. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevlett.130.098202\">https://doi.org/10.1103/physrevlett.130.098202</a>","ama":"Grosjean GM, Waitukaitis SR. Single-collision statistics reveal a global mechanism driven by sample history for contact electrification in granular media. <i>Physical Review Letters</i>. 2023;130(9). doi:<a href=\"https://doi.org/10.1103/physrevlett.130.098202\">10.1103/physrevlett.130.098202</a>","ista":"Grosjean GM, Waitukaitis SR. 2023. Single-collision statistics reveal a global mechanism driven by sample history for contact electrification in granular media. Physical Review Letters. 130(9), 098202.","chicago":"Grosjean, Galien M, and Scott R Waitukaitis. “Single-Collision Statistics Reveal a Global Mechanism Driven by Sample History for Contact Electrification in Granular Media.” <i>Physical Review Letters</i>. American Physical Society, 2023. <a href=\"https://doi.org/10.1103/physrevlett.130.098202\">https://doi.org/10.1103/physrevlett.130.098202</a>.","ieee":"G. M. Grosjean and S. R. Waitukaitis, “Single-collision statistics reveal a global mechanism driven by sample history for contact electrification in granular media,” <i>Physical Review Letters</i>, vol. 130, no. 9. American Physical Society, 2023.","mla":"Grosjean, Galien M., and Scott R. Waitukaitis. “Single-Collision Statistics Reveal a Global Mechanism Driven by Sample History for Contact Electrification in Granular Media.” <i>Physical Review Letters</i>, vol. 130, no. 9, 098202, American Physical Society, 2023, doi:<a href=\"https://doi.org/10.1103/physrevlett.130.098202\">10.1103/physrevlett.130.098202</a>.","short":"G.M. Grosjean, S.R. Waitukaitis, Physical Review Letters 130 (2023)."},"date_updated":"2023-08-22T08:41:32Z","date_created":"2023-02-28T12:14:46Z","department":[{"_id":"ScWa"}],"intvolume":"       130"},{"date_updated":"2023-08-01T13:36:11Z","date_created":"2023-03-05T23:01:04Z","department":[{"_id":"BiCh"}],"intvolume":"        14","month":"02","article_type":"original","acknowledgement":"BC thanks Daan Frenkel for stimulating discussions. We thank Aleks Reinhardt, Daan Frenkel, Marius Millot, Federica Coppari, Rhys Bunting, and Chris J. Pickard for critically reading the manuscript and providing useful suggestions. BC acknowledges resources provided by the Cambridge Tier-2 system operated by the University of Cambridge Research Computing Service funded by EPSRC Tier-2 capital grant EP/P020259/1. SH acknowledges support from LDRD 19-ERD-031 and computing support from the Lawrence Livermore National Laboratory (LLNL) Institutional Computing Grand Challenge program. Lawrence Livermore National Laboratory is operated by Lawrence Livermore National Security, LLC, for the U.S. Department of Energy, National Nuclear Security Administration under Contract DE-AC52-07NA27344. MB acknowledges support by the European Horizon 2020 program within the Marie Skłodowska-Curie actions (xICE grant number 894725), funding from the NOMIS foundation and computational resources at the North-German Supercomputing Alliance (HLRN) facilities.","citation":{"chicago":"Cheng, Bingqing, Sebastien Hamel, and Mandy Bethkenhagen. “Thermodynamics of Diamond Formation from Hydrocarbon Mixtures in Planets.” <i>Nature Communications</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1038/s41467-023-36841-1\">https://doi.org/10.1038/s41467-023-36841-1</a>.","ieee":"B. Cheng, S. Hamel, and M. Bethkenhagen, “Thermodynamics of diamond formation from hydrocarbon mixtures in planets,” <i>Nature Communications</i>, vol. 14. Springer Nature, 2023.","short":"B. Cheng, S. Hamel, M. Bethkenhagen, Nature Communications 14 (2023).","mla":"Cheng, Bingqing, et al. “Thermodynamics of Diamond Formation from Hydrocarbon Mixtures in Planets.” <i>Nature Communications</i>, vol. 14, 1104, Springer Nature, 2023, doi:<a href=\"https://doi.org/10.1038/s41467-023-36841-1\">10.1038/s41467-023-36841-1</a>.","apa":"Cheng, B., Hamel, S., &#38; Bethkenhagen, M. (2023). Thermodynamics of diamond formation from hydrocarbon mixtures in planets. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-023-36841-1\">https://doi.org/10.1038/s41467-023-36841-1</a>","ama":"Cheng B, Hamel S, Bethkenhagen M. Thermodynamics of diamond formation from hydrocarbon mixtures in planets. <i>Nature Communications</i>. 2023;14. doi:<a href=\"https://doi.org/10.1038/s41467-023-36841-1\">10.1038/s41467-023-36841-1</a>","ista":"Cheng B, Hamel S, Bethkenhagen M. 2023. Thermodynamics of diamond formation from hydrocarbon mixtures in planets. Nature Communications. 14, 1104."},"_id":"12702","volume":14,"file":[{"creator":"cchlebak","file_name":"2023_NatComm_Cheng.pdf","file_size":1946443,"success":1,"file_id":"12713","checksum":"5ff61ad21511950c15abb73b18613883","date_updated":"2023-03-07T10:58:00Z","date_created":"2023-03-07T10:58:00Z","access_level":"open_access","relation":"main_file","content_type":"application/pdf"}],"project":[{"name":"NOMIS Fellowship Program","_id":"9B861AAC-BA93-11EA-9121-9846C619BF3A"}],"doi":"10.1038/s41467-023-36841-1","title":"Thermodynamics of diamond formation from hydrocarbon mixtures in planets","date_published":"2023-02-27T00:00:00Z","day":"27","isi":1,"publication":"Nature Communications","scopus_import":"1","publication_status":"published","type":"journal_article","quality_controlled":"1","publisher":"Springer Nature","has_accepted_license":"1","oa_version":"Published Version","status":"public","author":[{"orcid":"0000-0002-3584-9632","last_name":"Cheng","full_name":"Cheng, Bingqing","id":"cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9","first_name":"Bingqing"},{"first_name":"Sebastien","full_name":"Hamel, Sebastien","last_name":"Hamel"},{"orcid":"0000-0002-1838-2129","last_name":"Bethkenhagen","full_name":"Bethkenhagen, Mandy","first_name":"Mandy","id":"201939f4-803f-11ed-ab7e-d8da4bd1517f"}],"year":"2023","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publication_identifier":{"eissn":["2041-1723"]},"pmid":1,"language":[{"iso":"eng"}],"ddc":["540"],"oa":1,"external_id":{"pmid":["36843123"],"isi":["000939678300002"]},"abstract":[{"text":"Hydrocarbon mixtures are extremely abundant in the Universe, and diamond formation from them can play a crucial role in shaping the interior structure and evolution of planets. With first-principles accuracy, we first estimate the melting line of diamond, and then reveal the nature of chemical bonding in hydrocarbons at extreme conditions. We finally establish the pressure-temperature phase boundary where it is thermodynamically possible for diamond to form from hydrocarbon mixtures with different atomic fractions of carbon. Notably, here we show a depletion zone at pressures above 200 GPa and temperatures below 3000 K-3500 K where diamond formation is thermodynamically favorable regardless of the carbon atomic fraction, due to a phase separation mechanism. The cooler condition of the interior of Neptune compared to Uranus means that the former is much more likely to contain the depletion zone. Our findings can help explain the dichotomy of the two ice giants manifested by the low luminosity of Uranus, and lead to a better understanding of (exo-)planetary formation and evolution.","lang":"eng"}],"article_processing_charge":"No","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_number":"1104","file_date_updated":"2023-03-07T10:58:00Z"},{"external_id":{"isi":["000936534100012"],"arxiv":["2204.07373"]},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_processing_charge":"No","abstract":[{"lang":"eng","text":"Adversarial training (i.e., training on adversarially perturbed input data) is a well-studied method for making neural networks robust to potential adversarial attacks during inference. However, the improved robustness does not come for free but rather is accompanied by a decrease in overall model accuracy and performance. Recent work has shown that, in practical robot learning applications, the effects of adversarial training do not pose a fair trade-off but inflict a net loss when measured in holistic robot performance. This work revisits the robustness-accuracy trade-off in robot learning by systematically analyzing if recent advances in robust training methods and theory in conjunction with adversarial robot learning, are capable of making adversarial training suitable for real-world robot applications. We evaluate three different robot learning tasks ranging from autonomous driving in a high-fidelity environment amenable to sim-to-real deployment to mobile robot navigation and gesture recognition. Our results demonstrate that, while these techniques make incremental improvements on the trade-off on a relative scale, the negative impact on the nominal accuracy caused by adversarial training still outweighs the improved robustness by an order of magnitude. We conclude that although progress is happening, further advances in robust learning methods are necessary before they can benefit robot learning tasks in practice."}],"file_date_updated":"2023-03-07T12:22:23Z","language":[{"iso":"eng"}],"ddc":["000"],"oa":1,"year":"2023","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publication_identifier":{"eissn":["2377-3766"]},"oa_version":"Published Version","status":"public","author":[{"id":"3DC22916-F248-11E8-B48F-1D18A9856A87","first_name":"Mathias","last_name":"Lechner","full_name":"Lechner, Mathias"},{"full_name":"Amini, Alexander","last_name":"Amini","first_name":"Alexander"},{"full_name":"Rus, Daniela","last_name":"Rus","first_name":"Daniela"},{"id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A","orcid":"0000-0002-2985-7724","last_name":"Henzinger","full_name":"Henzinger, Thomas A"}],"page":"1595-1602","related_material":{"record":[{"id":"11366","relation":"earlier_version","status":"public"}]},"type":"journal_article","publication_status":"published","quality_controlled":"1","scopus_import":"1","publisher":"Institute of Electrical and Electronics Engineers","arxiv":1,"has_accepted_license":"1","day":"01","title":"Revisiting the adversarial robustness-accuracy tradeoff in robot learning","date_published":"2023-03-01T00:00:00Z","publication":"IEEE Robotics and Automation Letters","isi":1,"issue":"3","_id":"12704","file":[{"content_type":"application/pdf","success":1,"file_id":"12714","checksum":"5a75dcd326ea66685de2b1aaec259e85","date_created":"2023-03-07T12:22:23Z","date_updated":"2023-03-07T12:22:23Z","access_level":"open_access","relation":"main_file","file_name":"2023_IEEERobAutLetters_Lechner.pdf","file_size":944052,"creator":"cchlebak"}],"volume":8,"doi":"10.1109/LRA.2023.3240930","department":[{"_id":"ToHe"}],"date_updated":"2023-08-01T13:36:50Z","date_created":"2023-03-05T23:01:04Z","intvolume":"         8","article_type":"original","month":"03","citation":{"apa":"Lechner, M., Amini, A., Rus, D., &#38; Henzinger, T. A. (2023). Revisiting the adversarial robustness-accuracy tradeoff in robot learning. <i>IEEE Robotics and Automation Letters</i>. Institute of Electrical and Electronics Engineers. <a href=\"https://doi.org/10.1109/LRA.2023.3240930\">https://doi.org/10.1109/LRA.2023.3240930</a>","ama":"Lechner M, Amini A, Rus D, Henzinger TA. Revisiting the adversarial robustness-accuracy tradeoff in robot learning. <i>IEEE Robotics and Automation Letters</i>. 2023;8(3):1595-1602. doi:<a href=\"https://doi.org/10.1109/LRA.2023.3240930\">10.1109/LRA.2023.3240930</a>","ista":"Lechner M, Amini A, Rus D, Henzinger TA. 2023. Revisiting the adversarial robustness-accuracy tradeoff in robot learning. IEEE Robotics and Automation Letters. 8(3), 1595–1602.","chicago":"Lechner, Mathias, Alexander Amini, Daniela Rus, and Thomas A Henzinger. “Revisiting the Adversarial Robustness-Accuracy Tradeoff in Robot Learning.” <i>IEEE Robotics and Automation Letters</i>. Institute of Electrical and Electronics Engineers, 2023. <a href=\"https://doi.org/10.1109/LRA.2023.3240930\">https://doi.org/10.1109/LRA.2023.3240930</a>.","ieee":"M. Lechner, A. Amini, D. Rus, and T. A. Henzinger, “Revisiting the adversarial robustness-accuracy tradeoff in robot learning,” <i>IEEE Robotics and Automation Letters</i>, vol. 8, no. 3. Institute of Electrical and Electronics Engineers, pp. 1595–1602, 2023.","mla":"Lechner, Mathias, et al. “Revisiting the Adversarial Robustness-Accuracy Tradeoff in Robot Learning.” <i>IEEE Robotics and Automation Letters</i>, vol. 8, no. 3, Institute of Electrical and Electronics Engineers, 2023, pp. 1595–602, doi:<a href=\"https://doi.org/10.1109/LRA.2023.3240930\">10.1109/LRA.2023.3240930</a>.","short":"M. Lechner, A. Amini, D. Rus, T.A. Henzinger, IEEE Robotics and Automation Letters 8 (2023) 1595–1602."},"acknowledgement":"We thank Christoph Lampert for inspiring this work. The\r\nviews and conclusions contained in this document are those of\r\nthe authors and should not be interpreted as representing the\r\nofficial policies, either expressed or implied, of the United States\r\nAir Force or the U.S. Government. The U.S. Government is\r\nauthorized to reproduce and distribute reprints for Government\r\npurposes notwithstanding any copyright notation herein."},{"department":[{"_id":"AnSa"}],"date_created":"2023-03-05T23:01:05Z","date_updated":"2023-10-03T11:31:51Z","intvolume":"       158","article_type":"original","month":"02","citation":{"apa":"Sorichetti, V., Ninarello, A., Ruiz-Franco, J., Hugouvieux, V., Zaccarelli, E., Micheletti, C., … Rovigatti, L. (2023). Structure and elasticity of model disordered, polydisperse, and defect-free polymer networks. <i>Journal of Chemical Physics</i>. American Institute of Physics. <a href=\"https://doi.org/10.1063/5.0134271\">https://doi.org/10.1063/5.0134271</a>","ama":"Sorichetti V, Ninarello A, Ruiz-Franco J, et al. Structure and elasticity of model disordered, polydisperse, and defect-free polymer networks. <i>Journal of Chemical Physics</i>. 2023;158(7). doi:<a href=\"https://doi.org/10.1063/5.0134271\">10.1063/5.0134271</a>","ista":"Sorichetti V, Ninarello A, Ruiz-Franco J, Hugouvieux V, Zaccarelli E, Micheletti C, Kob W, Rovigatti L. 2023. Structure and elasticity of model disordered, polydisperse, and defect-free polymer networks. Journal of Chemical Physics. 158(7), 074905.","chicago":"Sorichetti, Valerio, Andrea Ninarello, José Ruiz-Franco, Virginie Hugouvieux, Emanuela Zaccarelli, Cristian Micheletti, Walter Kob, and Lorenzo Rovigatti. “Structure and Elasticity of Model Disordered, Polydisperse, and Defect-Free Polymer Networks.” <i>Journal of Chemical Physics</i>. American Institute of Physics, 2023. <a href=\"https://doi.org/10.1063/5.0134271\">https://doi.org/10.1063/5.0134271</a>.","ieee":"V. Sorichetti <i>et al.</i>, “Structure and elasticity of model disordered, polydisperse, and defect-free polymer networks,” <i>Journal of Chemical Physics</i>, vol. 158, no. 7. American Institute of Physics, 2023.","short":"V. Sorichetti, A. Ninarello, J. Ruiz-Franco, V. Hugouvieux, E. Zaccarelli, C. Micheletti, W. Kob, L. Rovigatti, Journal of Chemical Physics 158 (2023).","mla":"Sorichetti, Valerio, et al. “Structure and Elasticity of Model Disordered, Polydisperse, and Defect-Free Polymer Networks.” <i>Journal of Chemical Physics</i>, vol. 158, no. 7, 074905, American Institute of Physics, 2023, doi:<a href=\"https://doi.org/10.1063/5.0134271\">10.1063/5.0134271</a>."},"acknowledgement":"We thank Michael Lang for helpful discussions. We acknowledge financial support from the European Research Council (ERC Consolidator Grant No. 681597, MIMIC) and from LabEx NUMEV (Grant No. ANR-10-LABX-20) funded by the “Investissements d’Avenir” French Government program, managed by the French National Research Agency (ANR). W.K. is a senior member of the Institut Universitaire de France.","issue":"7","_id":"12705","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2211.04810"}],"volume":158,"doi":"10.1063/5.0134271","day":"21","title":"Structure and elasticity of model disordered, polydisperse, and defect-free polymer networks","date_published":"2023-02-21T00:00:00Z","publication":"Journal of Chemical Physics","isi":1,"type":"journal_article","publication_status":"published","scopus_import":"1","quality_controlled":"1","publisher":"American Institute of Physics","arxiv":1,"oa_version":"Preprint","status":"public","author":[{"first_name":"Valerio","id":"ef8a92cb-c7b6-11ec-8bea-e1fd5847bc5b","last_name":"Sorichetti","full_name":"Sorichetti, Valerio","orcid":"0000-0002-9645-6576"},{"full_name":"Ninarello, Andrea","last_name":"Ninarello","first_name":"Andrea"},{"full_name":"Ruiz-Franco, José","last_name":"Ruiz-Franco","first_name":"José"},{"first_name":"Virginie","last_name":"Hugouvieux","full_name":"Hugouvieux, Virginie"},{"first_name":"Emanuela","last_name":"Zaccarelli","full_name":"Zaccarelli, Emanuela"},{"last_name":"Micheletti","full_name":"Micheletti, Cristian","first_name":"Cristian"},{"full_name":"Kob, Walter","last_name":"Kob","first_name":"Walter"},{"last_name":"Rovigatti","full_name":"Rovigatti, Lorenzo","first_name":"Lorenzo"}],"year":"2023","publication_identifier":{"issn":["0021-9606"],"eissn":["1089-7690"]},"pmid":1,"language":[{"iso":"eng"}],"oa":1,"external_id":{"isi":["000936943800002"],"pmid":["36813705"],"arxiv":["2211.04810"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"The elasticity of disordered and polydisperse polymer networks is a fundamental problem of soft matter physics that is still open. Here, we self-assemble polymer networks via simulations of a mixture of bivalent and tri- or tetravalent patchy particles, which result in an exponential strand length distribution analogous to that of experimental randomly cross-linked systems. After assembly, the network connectivity and topology are frozen and the resulting system is characterized. We find that the fractal structure of the network depends on the number density at which the assembly has been carried out, but that systems with the same mean valence and same assembly density have the same structural properties. Moreover, we compute the long-time limit of the mean-squared displacement, also known as the (squared) localization length, of the cross-links and of the middle monomers of the strands, showing that the dynamics of long strands is well described by the tube model. Finally, we find a relation connecting these two localization lengths at high density and connect the cross-link localization length to the shear modulus of the system."}],"article_processing_charge":"No","article_number":"074905"},{"has_accepted_license":"1","publisher":"Public Library of Science","quality_controlled":"1","publication_status":"published","scopus_import":"1","type":"journal_article","publication":"PLoS One","isi":1,"day":"27","title":"Empirical parameterisation and dynamical analysis of the allometric Rosenzweig-MacArthur equations","date_published":"2023-02-27T00:00:00Z","doi":"10.1371/journal.pone.0279838","file":[{"file_name":"2023_PLOSOne_Mckerral.pdf","file_size":1257003,"creator":"cchlebak","content_type":"application/pdf","file_id":"12712","checksum":"798ed5739a4117b03173e5d56e0534c9","access_level":"open_access","relation":"main_file","date_updated":"2023-03-07T10:26:45Z","date_created":"2023-03-07T10:26:45Z","success":1}],"volume":18,"_id":"12706","issue":"2","citation":{"chicago":"Mckerral, Jody C., Maria Kleshnina, Vladimir Ejov, Louise Bartle, James G. Mitchell, and Jerzy A. Filar. “Empirical Parameterisation and Dynamical Analysis of the Allometric Rosenzweig-MacArthur Equations.” <i>PLoS One</i>. Public Library of Science, 2023. <a href=\"https://doi.org/10.1371/journal.pone.0279838\">https://doi.org/10.1371/journal.pone.0279838</a>.","ieee":"J. C. Mckerral, M. Kleshnina, V. Ejov, L. Bartle, J. G. Mitchell, and J. A. Filar, “Empirical parameterisation and dynamical analysis of the allometric Rosenzweig-MacArthur equations,” <i>PLoS One</i>, vol. 18, no. 2. Public Library of Science, p. e0279838, 2023.","short":"J.C. Mckerral, M. Kleshnina, V. Ejov, L. Bartle, J.G. Mitchell, J.A. Filar, PLoS One 18 (2023) e0279838.","mla":"Mckerral, Jody C., et al. “Empirical Parameterisation and Dynamical Analysis of the Allometric Rosenzweig-MacArthur Equations.” <i>PLoS One</i>, vol. 18, no. 2, Public Library of Science, 2023, p. e0279838, doi:<a href=\"https://doi.org/10.1371/journal.pone.0279838\">10.1371/journal.pone.0279838</a>.","apa":"Mckerral, J. C., Kleshnina, M., Ejov, V., Bartle, L., Mitchell, J. G., &#38; Filar, J. A. (2023). Empirical parameterisation and dynamical analysis of the allometric Rosenzweig-MacArthur equations. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0279838\">https://doi.org/10.1371/journal.pone.0279838</a>","ama":"Mckerral JC, Kleshnina M, Ejov V, Bartle L, Mitchell JG, Filar JA. Empirical parameterisation and dynamical analysis of the allometric Rosenzweig-MacArthur equations. <i>PLoS One</i>. 2023;18(2):e0279838. doi:<a href=\"https://doi.org/10.1371/journal.pone.0279838\">10.1371/journal.pone.0279838</a>","ista":"Mckerral JC, Kleshnina M, Ejov V, Bartle L, Mitchell JG, Filar JA. 2023. Empirical parameterisation and dynamical analysis of the allometric Rosenzweig-MacArthur equations. PLoS One. 18(2), e0279838."},"acknowledgement":"This research was supported by an Australian Government Research Training Program\r\n(RTP) Scholarship to JCM (https://www.dese.gov.au), and LB is supported by the Centre de\r\nrecherche sur le vieillissement Fellowship Program. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","month":"02","article_type":"original","intvolume":"        18","department":[{"_id":"KrCh"}],"date_created":"2023-03-05T23:01:05Z","date_updated":"2023-10-17T12:53:30Z","file_date_updated":"2023-03-07T10:26:45Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"Allometric settings of population dynamics models are appealing due to their parsimonious nature and broad utility when studying system level effects. Here, we parameterise the size-scaled Rosenzweig-MacArthur differential equations to eliminate prey-mass dependency, facilitating an in depth analytic study of the equations which incorporates scaling parameters’ contributions to coexistence. We define the functional response term to match empirical findings, and examine situations where metabolic theory derivations and observation diverge. The dynamical properties of the Rosenzweig-MacArthur system, encompassing the distribution of size-abundance equilibria, the scaling of period and amplitude of population cycling, and relationships between predator and prey abundances, are consistent with empirical observation. Our parameterisation is an accurate minimal model across 15+ orders of mass magnitude."}],"article_processing_charge":"No","external_id":{"pmid":["36848357"],"isi":["000996122900022"]},"oa":1,"ddc":["000"],"language":[{"iso":"eng"}],"pmid":1,"publication_identifier":{"eissn":["1932-6203"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2023","author":[{"first_name":"Jody C.","full_name":"Mckerral, Jody C.","last_name":"Mckerral"},{"first_name":"Maria","id":"4E21749C-F248-11E8-B48F-1D18A9856A87","full_name":"Kleshnina, Maria","last_name":"Kleshnina"},{"first_name":"Vladimir","full_name":"Ejov, Vladimir","last_name":"Ejov"},{"full_name":"Bartle, Louise","last_name":"Bartle","first_name":"Louise"},{"full_name":"Mitchell, James G.","last_name":"Mitchell","first_name":"James G."},{"full_name":"Filar, Jerzy A.","last_name":"Filar","first_name":"Jerzy A."}],"page":"e0279838","status":"public","oa_version":"Published Version"},{"year":"2023","ec_funded":1,"publication_identifier":{"issn":["1350-7265"]},"oa_version":"Preprint","status":"public","page":"1063-1079","author":[{"orcid":"0000-0001-5366-9603","last_name":"Erdös","full_name":"Erdös, László","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0003-1559-1205","last_name":"Xu","full_name":"Xu, Yuanyuan","id":"7902bdb1-a2a4-11eb-a164-c9216f71aea3","first_name":"Yuanyuan"}],"external_id":{"arxiv":["2112.12093 "],"isi":["000947270100008"]},"article_processing_charge":"No","abstract":[{"text":"We establish precise right-tail small deviation estimates for the largest eigenvalue of real symmetric and complex Hermitian matrices whose entries are independent random variables with uniformly bounded moments. The proof relies on a Green function comparison along a continuous interpolating matrix flow for a long time. Less precise estimates are also obtained in the left tail.","lang":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"oa":1,"issue":"2","_id":"12707","main_file_link":[{"url":"https://arxiv.org/abs/2112.12093","open_access":"1"}],"volume":29,"project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","call_identifier":"H2020","name":"Random matrices beyond Wigner-Dyson-Mehta","grant_number":"101020331"}],"doi":"10.3150/22-BEJ1490","date_created":"2023-03-05T23:01:05Z","date_updated":"2023-10-04T10:21:07Z","department":[{"_id":"LaEr"}],"intvolume":"        29","month":"05","article_type":"original","citation":{"apa":"Erdös, L., &#38; Xu, Y. (2023). Small deviation estimates for the largest eigenvalue of Wigner matrices. <i>Bernoulli</i>. Bernoulli Society for Mathematical Statistics and Probability. <a href=\"https://doi.org/10.3150/22-BEJ1490\">https://doi.org/10.3150/22-BEJ1490</a>","ama":"Erdös L, Xu Y. Small deviation estimates for the largest eigenvalue of Wigner matrices. <i>Bernoulli</i>. 2023;29(2):1063-1079. doi:<a href=\"https://doi.org/10.3150/22-BEJ1490\">10.3150/22-BEJ1490</a>","ista":"Erdös L, Xu Y. 2023. Small deviation estimates for the largest eigenvalue of Wigner matrices. Bernoulli. 29(2), 1063–1079.","chicago":"Erdös, László, and Yuanyuan Xu. “Small Deviation Estimates for the Largest Eigenvalue of Wigner Matrices.” <i>Bernoulli</i>. Bernoulli Society for Mathematical Statistics and Probability, 2023. <a href=\"https://doi.org/10.3150/22-BEJ1490\">https://doi.org/10.3150/22-BEJ1490</a>.","ieee":"L. Erdös and Y. Xu, “Small deviation estimates for the largest eigenvalue of Wigner matrices,” <i>Bernoulli</i>, vol. 29, no. 2. Bernoulli Society for Mathematical Statistics and Probability, pp. 1063–1079, 2023.","mla":"Erdös, László, and Yuanyuan Xu. “Small Deviation Estimates for the Largest Eigenvalue of Wigner Matrices.” <i>Bernoulli</i>, vol. 29, no. 2, Bernoulli Society for Mathematical Statistics and Probability, 2023, pp. 1063–79, doi:<a href=\"https://doi.org/10.3150/22-BEJ1490\">10.3150/22-BEJ1490</a>.","short":"L. Erdös, Y. Xu, Bernoulli 29 (2023) 1063–1079."},"type":"journal_article","scopus_import":"1","quality_controlled":"1","publication_status":"published","publisher":"Bernoulli Society for Mathematical Statistics and Probability","arxiv":1,"title":"Small deviation estimates for the largest eigenvalue of Wigner matrices","date_published":"2023-05-01T00:00:00Z","day":"01","isi":1,"publication":"Bernoulli"},{"volume":19,"file":[{"content_type":"application/pdf","date_updated":"2023-03-07T09:19:41Z","date_created":"2023-03-07T09:19:41Z","access_level":"open_access","relation":"main_file","checksum":"af95aa18b9b01e32fb8f13477c0e2687","file_id":"12711","success":1,"file_name":"2023_SoftMatter_Araujo.pdf","file_size":3581939,"creator":"cchlebak"}],"project":[{"name":"Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines","grant_number":"802960","call_identifier":"H2020","_id":"eba2549b-77a9-11ec-83b8-a81e493eae4e"}],"doi":"10.1039/d2sm01562e","_id":"12708","article_type":"original","month":"02","acknowledgement":"All authors are grateful to the Lorentz Center for providing a venue for stimulating scientific discussions and to sponsor a workshop on the topic of “Self-organisation under confinement” along with the 4TU Federation, the J. M. Burgers Center for Fluid Dynamics and the MESA+ Institute for Nanotechnology at the University of Twente. The authors are also grateful to Paolo Malgaretti, Federico Toschi, Twan Wilting and Jaap den Toonder for valuable feedback. N. A. acknowledges financial support from the Portuguese Foundation for Science and Technology (FCT) under Contracts no. PTDC/FIS-MAC/28146/2017 (LISBOA-01-0145-FEDER-028146), UIDB/00618/2020, and UIDP/00618/2020. L. M. C. J. acknowledges financial support from the Netherlands Organisation for Scientific Research (NWO) through a START-UP, Physics Projectruimte, and Vidi grant. I. C. was supported in part by a grant from by the Army Research Office (ARO W911NF-18-1-0032) and the Cornell Center for Materials Research (DMR-1719875). O. D. acknowledges funding by the Agence Nationale pour la Recherche under Grant No ANR-18-CE33-0006 MSR. M. D. acknowledges financial support from the European Research Council (Grant No. ERC-2019-ADV-H2020 884902 SoftML). W. M. D. acknowledges funding from a BBSRC New Investigator Grant (BB/R018383/1). S. G. was supported by DARPA Young Faculty Award # D19AP00046, and NSF IIS grant # 1955210. H. G. acknowledges financial support from the Netherlands Organisation for Scientific Research (NWO) through Veni Grant No. 680-47-451. R. G. acknowledges support from the Max Planck School Matter to Life and the MaxSynBio Consortium, which are jointly funded by the Federal Ministry of Education and Research (BMBF) of Germany, and the Max Planck Society. L. I. acknowledges funding from the Horizon Europe ERC Consolidator Grant ACTIVE_ ADAPTIVE (Grant No. 101001514). G. H. K. gratefully acknowledges the NWO Talent Programme which is financed by the Dutch Research Council (project number VI.C.182.004). H. L. and N. V. acknowledge funding from the Deutsche Forschungsgemeinschaft (DFG) under grant numbers VO 1824/8-1 and LO 418/22-1. R. M. acknowledges funding from the Deutsche Forschungsgemeinschaft (DFG) under grant number ME 1535/13-1 and ME 1535/16-1. M. P. acknowledges funding from the Ramón y Cajal Program, grant no. RYC-2018-02534, and the Leverhulme Trust, grant no. RPG-2018-345. A. Š. acknowledges financial support from the European Research Council (Grant No. ERC-2018-STG-H2020 802960 NEPA). A. S. acknowledges funding from an ATTRACT Investigator Grant (No. A17/MS/11572821/MBRACE) from the Luxembourg National Research Fund. C. S. acknowledges funding from the French Agence Nationale pour la Recherche (ANR), grant ANR-14-CE090006 and ANR-12-BSV5001401, by the Fondation pour la Recherche Médicale (FRM), grant DEQ20120323737, and from the PIC3I of Institut Curie, France. I. T. acknowledges funding from grant IED2019-00058I/AEI/10.13039/501100011033. M. P. and I. T. also acknowledge funding from grant PID2019-104232B-I00/AEI/10.13039/501100011033 and from the H2020 MSCA ITN PHYMOT (Grant agreement No 95591). I. Z. acknowledges funding from Project PID2020-114839GB-I00 MINECO/AEI/FEDER, UE. A. M. acknowledges funding from the European Research Council, Starting Grant No. 678573 NanoPacks. G. V. acknowledges sponsorship for this work by the US Office of Naval Research Global (Award No. N62909-18-1-2170).","citation":{"ista":"Araújo NAM, Janssen LMC, Barois T, Boffetta G, Cohen I, Corbetta A, Dauchot O, Dijkstra M, Durham WM, Dussutour A, Garnier S, Gelderblom H, Golestanian R, Isa L, Koenderink GH, Löwen H, Metzler R, Polin M, Royall CP, Šarić A, Sengupta A, Sykes C, Trianni V, Tuval I, Vogel N, Yeomans JM, Zuriguel I, Marin A, Volpe G. 2023. Steering self-organisation through confinement. Soft Matter. 19, 1695–1704.","apa":"Araújo, N. A. M., Janssen, L. M. C., Barois, T., Boffetta, G., Cohen, I., Corbetta, A., … Volpe, G. (2023). Steering self-organisation through confinement. <i>Soft Matter</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d2sm01562e\">https://doi.org/10.1039/d2sm01562e</a>","ama":"Araújo NAM, Janssen LMC, Barois T, et al. Steering self-organisation through confinement. <i>Soft Matter</i>. 2023;19:1695-1704. doi:<a href=\"https://doi.org/10.1039/d2sm01562e\">10.1039/d2sm01562e</a>","ieee":"N. A. M. Araújo <i>et al.</i>, “Steering self-organisation through confinement,” <i>Soft Matter</i>, vol. 19. Royal Society of Chemistry, pp. 1695–1704, 2023.","short":"N.A.M. Araújo, L.M.C. Janssen, T. Barois, G. Boffetta, I. Cohen, A. Corbetta, O. Dauchot, M. Dijkstra, W.M. Durham, A. Dussutour, S. Garnier, H. Gelderblom, R. Golestanian, L. Isa, G.H. Koenderink, H. Löwen, R. Metzler, M. Polin, C.P. Royall, A. Šarić, A. Sengupta, C. Sykes, V. Trianni, I. Tuval, N. Vogel, J.M. Yeomans, I. Zuriguel, A. Marin, G. Volpe, Soft Matter 19 (2023) 1695–1704.","mla":"Araújo, Nuno A. M., et al. “Steering Self-Organisation through Confinement.” <i>Soft Matter</i>, vol. 19, Royal Society of Chemistry, 2023, pp. 1695–704, doi:<a href=\"https://doi.org/10.1039/d2sm01562e\">10.1039/d2sm01562e</a>.","chicago":"Araújo, Nuno A.M., Liesbeth M.C. Janssen, Thomas Barois, Guido Boffetta, Itai Cohen, Alessandro Corbetta, Olivier Dauchot, et al. “Steering Self-Organisation through Confinement.” <i>Soft Matter</i>. Royal Society of Chemistry, 2023. <a href=\"https://doi.org/10.1039/d2sm01562e\">https://doi.org/10.1039/d2sm01562e</a>."},"date_updated":"2023-08-01T13:28:39Z","date_created":"2023-03-05T23:01:06Z","department":[{"_id":"AnSa"}],"intvolume":"        19","has_accepted_license":"1","arxiv":1,"scopus_import":"1","publication_status":"published","type":"journal_article","quality_controlled":"1","publisher":"Royal Society of Chemistry","date_published":"2023-02-06T00:00:00Z","title":"Steering self-organisation through confinement","day":"06","isi":1,"publication":"Soft Matter","ec_funded":1,"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publication_identifier":{"eissn":["1744-6848"],"issn":["1744-683X"]},"year":"2023","page":"1695-1704","author":[{"first_name":"Nuno A.M.","full_name":"Araújo, Nuno A.M.","last_name":"Araújo"},{"first_name":"Liesbeth M.C.","last_name":"Janssen","full_name":"Janssen, Liesbeth M.C."},{"last_name":"Barois","full_name":"Barois, Thomas","first_name":"Thomas"},{"first_name":"Guido","last_name":"Boffetta","full_name":"Boffetta, Guido"},{"first_name":"Itai","last_name":"Cohen","full_name":"Cohen, Itai"},{"full_name":"Corbetta, Alessandro","last_name":"Corbetta","first_name":"Alessandro"},{"full_name":"Dauchot, Olivier","last_name":"Dauchot","first_name":"Olivier"},{"first_name":"Marjolein","full_name":"Dijkstra, Marjolein","last_name":"Dijkstra"},{"last_name":"Durham","full_name":"Durham, William M.","first_name":"William M."},{"first_name":"Audrey","last_name":"Dussutour","full_name":"Dussutour, Audrey"},{"first_name":"Simon","last_name":"Garnier","full_name":"Garnier, Simon"},{"last_name":"Gelderblom","full_name":"Gelderblom, Hanneke","first_name":"Hanneke"},{"first_name":"Ramin","last_name":"Golestanian","full_name":"Golestanian, Ramin"},{"last_name":"Isa","full_name":"Isa, Lucio","first_name":"Lucio"},{"last_name":"Koenderink","full_name":"Koenderink, Gijsje H.","first_name":"Gijsje H."},{"last_name":"Löwen","full_name":"Löwen, Hartmut","first_name":"Hartmut"},{"last_name":"Metzler","full_name":"Metzler, Ralf","first_name":"Ralf"},{"last_name":"Polin","full_name":"Polin, Marco","first_name":"Marco"},{"first_name":"C. Patrick","last_name":"Royall","full_name":"Royall, C. Patrick"},{"id":"bf63d406-f056-11eb-b41d-f263a6566d8b","first_name":"Anđela","orcid":"0000-0002-7854-2139","full_name":"Šarić, Anđela","last_name":"Šarić"},{"full_name":"Sengupta, Anupam","last_name":"Sengupta","first_name":"Anupam"},{"last_name":"Sykes","full_name":"Sykes, Cécile","first_name":"Cécile"},{"first_name":"Vito","full_name":"Trianni, Vito","last_name":"Trianni"},{"first_name":"Idan","full_name":"Tuval, Idan","last_name":"Tuval"},{"last_name":"Vogel","full_name":"Vogel, Nicolas","first_name":"Nicolas"},{"first_name":"Julia M.","full_name":"Yeomans, Julia M.","last_name":"Yeomans"},{"full_name":"Zuriguel, Iker","last_name":"Zuriguel","first_name":"Iker"},{"last_name":"Marin","full_name":"Marin, Alvaro","first_name":"Alvaro"},{"first_name":"Giorgio","full_name":"Volpe, Giorgio","last_name":"Volpe"}],"oa_version":"Published Version","status":"public","file_date_updated":"2023-03-07T09:19:41Z","external_id":{"arxiv":["2204.10059"],"isi":["000940388100001"]},"abstract":[{"text":"Self-organisation is the spontaneous emergence of spatio-temporal structures and patterns from the interaction of smaller individual units. Examples are found across many scales in very different systems and scientific disciplines, from physics, materials science and robotics to biology, geophysics and astronomy. Recent research has highlighted how self-organisation can be both mediated and controlled by confinement. Confinement is an action over a system that limits its units’ translational and rotational degrees of freedom, thus also influencing the system's phase space probability density; it can function as either a catalyst or inhibitor of self-organisation. Confinement can then become a means to actively steer the emergence or suppression of collective phenomena in space and time. Here, to provide a common framework and perspective for future research, we examine the role of confinement in the self-organisation of soft-matter systems and identify overarching scientific challenges that need to be addressed to harness its full scientific and technological potential in soft matter and related fields. By drawing analogies with other disciplines, this framework will accelerate a common deeper understanding of self-organisation and trigger the development of innovative strategies to steer it using confinement, with impact on, e.g., the design of smarter materials, tissue engineering for biomedicine and in guiding active matter.","lang":"eng"}],"article_processing_charge":"No","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","ddc":["540"],"oa":1,"language":[{"iso":"eng"}]},{"publication_identifier":{"eissn":["1432-0444"],"issn":["0179-5376"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2023","related_material":{"record":[{"id":"9605","status":"public","relation":"earlier_version"}]},"page":"376-405","author":[{"last_name":"Corbet","full_name":"Corbet, René","first_name":"René"},{"id":"36E4574A-F248-11E8-B48F-1D18A9856A87","first_name":"Michael","full_name":"Kerber, Michael","last_name":"Kerber","orcid":"0000-0002-8030-9299"},{"last_name":"Lesnick","full_name":"Lesnick, Michael","first_name":"Michael"},{"full_name":"Osang, Georg F","last_name":"Osang","orcid":"0000-0002-8882-5116","first_name":"Georg F","id":"464B40D6-F248-11E8-B48F-1D18A9856A87"}],"status":"public","oa_version":"Published Version","file_date_updated":"2023-03-07T14:40:14Z","abstract":[{"lang":"eng","text":"Given a finite set A ⊂ ℝ^d, let Cov_{r,k} denote the set of all points within distance r to at least k points of A. Allowing r and k to vary, we obtain a 2-parameter family of spaces that grow larger when r increases or k decreases, called the multicover bifiltration. Motivated by the problem of computing the homology of this bifiltration, we introduce two closely related combinatorial bifiltrations, one polyhedral and the other simplicial, which are both topologically equivalent to the multicover bifiltration and far smaller than a Čech-based model considered in prior work of Sheehy. Our polyhedral construction is a bifiltration of the rhomboid tiling of Edelsbrunner and Osang, and can be efficiently computed using a variant of an algorithm given by these authors as well. Using an implementation for dimension 2 and 3, we provide experimental results. Our simplicial construction is useful for understanding the polyhedral construction and proving its correctness."}],"article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"arxiv":["2103.07823"],"isi":["000936496800001"]},"oa":1,"ddc":["000"],"language":[{"iso":"eng"}],"doi":"10.1007/s00454-022-00476-8","volume":70,"file":[{"content_type":"application/pdf","date_created":"2023-03-07T14:40:14Z","date_updated":"2023-03-07T14:40:14Z","access_level":"open_access","relation":"main_file","file_id":"12715","checksum":"71ce7e59f7ee4620acc704fecca620c2","success":1,"file_name":"2023_DisCompGeo_Corbet.pdf","file_size":1359323,"creator":"cchlebak"}],"_id":"12709","acknowledgement":"We thank the anonymous reviewers for many helpful comments and suggestions, which led to substantial improvements of the paper. The first two authors were supported by the Austrian Science Fund (FWF) grant number P 29984-N35 and W1230. The first author was partly supported by an Austrian Marshall Plan Scholarship, and by the Brummer & Partners MathDataLab. A conference version of this paper was presented at the 37th International Symposium on Computational Geometry (SoCG 2021). Open access funding provided by the Royal Institute of Technology.","citation":{"ieee":"R. Corbet, M. Kerber, M. Lesnick, and G. F. Osang, “Computing the multicover bifiltration,” <i>Discrete and Computational Geometry</i>, vol. 70. Springer Nature, pp. 376–405, 2023.","short":"R. Corbet, M. Kerber, M. Lesnick, G.F. Osang, Discrete and Computational Geometry 70 (2023) 376–405.","mla":"Corbet, René, et al. “Computing the Multicover Bifiltration.” <i>Discrete and Computational Geometry</i>, vol. 70, Springer Nature, 2023, pp. 376–405, doi:<a href=\"https://doi.org/10.1007/s00454-022-00476-8\">10.1007/s00454-022-00476-8</a>.","chicago":"Corbet, René, Michael Kerber, Michael Lesnick, and Georg F Osang. “Computing the Multicover Bifiltration.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1007/s00454-022-00476-8\">https://doi.org/10.1007/s00454-022-00476-8</a>.","ista":"Corbet R, Kerber M, Lesnick M, Osang GF. 2023. Computing the multicover bifiltration. Discrete and Computational Geometry. 70, 376–405.","apa":"Corbet, R., Kerber, M., Lesnick, M., &#38; Osang, G. F. (2023). Computing the multicover bifiltration. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-022-00476-8\">https://doi.org/10.1007/s00454-022-00476-8</a>","ama":"Corbet R, Kerber M, Lesnick M, Osang GF. Computing the multicover bifiltration. <i>Discrete and Computational Geometry</i>. 2023;70:376-405. doi:<a href=\"https://doi.org/10.1007/s00454-022-00476-8\">10.1007/s00454-022-00476-8</a>"},"article_type":"original","month":"09","intvolume":"        70","date_created":"2023-03-05T23:01:06Z","date_updated":"2023-10-04T12:03:40Z","department":[{"_id":"HeEd"}],"has_accepted_license":"1","arxiv":1,"publisher":"Springer Nature","scopus_import":"1","type":"journal_article","publication_status":"published","quality_controlled":"1","isi":1,"publication":"Discrete and Computational Geometry","date_published":"2023-09-01T00:00:00Z","title":"Computing the multicover bifiltration","day":"01"},{"oa_version":"Published Version","status":"public","author":[{"first_name":"Barbara","full_name":"Schamberger, Barbara","last_name":"Schamberger"},{"full_name":"Ziege, Ricardo","last_name":"Ziege","first_name":"Ricardo"},{"full_name":"Anselme, Karine","last_name":"Anselme","first_name":"Karine"},{"first_name":"Martine","last_name":"Ben Amar","full_name":"Ben Amar, Martine"},{"last_name":"Bykowski","full_name":"Bykowski, Michał","first_name":"Michał"},{"first_name":"André P.G.","full_name":"Castro, André P.G.","last_name":"Castro"},{"last_name":"Cipitria","full_name":"Cipitria, Amaia","first_name":"Amaia"},{"last_name":"Coles","full_name":"Coles, Rhoslyn A.","first_name":"Rhoslyn A."},{"first_name":"Rumiana","full_name":"Dimova, Rumiana","last_name":"Dimova"},{"last_name":"Eder","full_name":"Eder, Michaela","first_name":"Michaela"},{"first_name":"Sebastian","last_name":"Ehrig","full_name":"Ehrig, Sebastian"},{"last_name":"Escudero","full_name":"Escudero, Luis M.","first_name":"Luis M."},{"last_name":"Evans","full_name":"Evans, Myfanwy E.","first_name":"Myfanwy E."},{"first_name":"Paulo R.","full_name":"Fernandes, Paulo R.","last_name":"Fernandes"},{"full_name":"Fratzl, Peter","last_name":"Fratzl","first_name":"Peter"},{"full_name":"Geris, Liesbet","last_name":"Geris","first_name":"Liesbet"},{"first_name":"Notburga","last_name":"Gierlinger","full_name":"Gierlinger, Notburga"},{"first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6005-1561","full_name":"Hannezo, Edouard B","last_name":"Hannezo"},{"full_name":"Iglič, Aleš","last_name":"Iglič","first_name":"Aleš"},{"first_name":"Jacob J.K.","last_name":"Kirkensgaard","full_name":"Kirkensgaard, Jacob J.K."},{"first_name":"Philip","full_name":"Kollmannsberger, Philip","last_name":"Kollmannsberger"},{"last_name":"Kowalewska","full_name":"Kowalewska, Łucja","first_name":"Łucja"},{"last_name":"Kurniawan","full_name":"Kurniawan, Nicholas A.","first_name":"Nicholas A."},{"first_name":"Ioannis","last_name":"Papantoniou","full_name":"Papantoniou, Ioannis"},{"first_name":"Laurent","full_name":"Pieuchot, Laurent","last_name":"Pieuchot"},{"last_name":"Pires","full_name":"Pires, Tiago H.V.","first_name":"Tiago H.V."},{"first_name":"Lars D.","full_name":"Renner, Lars D.","last_name":"Renner"},{"first_name":"Andrew O.","last_name":"Sageman-Furnas","full_name":"Sageman-Furnas, Andrew O."},{"last_name":"Schröder-Turk","full_name":"Schröder-Turk, Gerd E.","first_name":"Gerd E."},{"last_name":"Sengupta","full_name":"Sengupta, Anupam","first_name":"Anupam"},{"first_name":"Vikas R.","last_name":"Sharma","full_name":"Sharma, Vikas R."},{"first_name":"Antonio","full_name":"Tagua, Antonio","last_name":"Tagua"},{"first_name":"Caterina","last_name":"Tomba","full_name":"Tomba, Caterina"},{"full_name":"Trepat, Xavier","last_name":"Trepat","first_name":"Xavier"},{"last_name":"Waters","full_name":"Waters, Sarah L.","first_name":"Sarah L."},{"last_name":"Yeo","full_name":"Yeo, Edwina F.","first_name":"Edwina F."},{"first_name":"Andreas","full_name":"Roschger, Andreas","last_name":"Roschger"},{"first_name":"Cécile M.","last_name":"Bidan","full_name":"Bidan, Cécile M."},{"last_name":"Dunlop","full_name":"Dunlop, John W.C.","first_name":"John W.C."}],"year":"2023","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publication_identifier":{"eissn":["1521-4095"],"issn":["0935-9648"]},"pmid":1,"language":[{"iso":"eng"}],"ddc":["570"],"oa":1,"external_id":{"pmid":["36461812"],"isi":["000941068900001"]},"article_processing_charge":"No","abstract":[{"text":"Surface curvature both emerges from, and influences the behavior of, living objects at length scales ranging from cell membranes to single cells to tissues and organs. The relevance of surface curvature in biology is supported by numerous experimental and theoretical investigations in recent years. In this review, first, a brief introduction to the key ideas of surface curvature in the context of biological systems is given and the challenges that arise when measuring surface curvature are discussed. Giving an overview of the emergence of curvature in biological systems, its significance at different length scales becomes apparent. On the other hand, summarizing current findings also shows that both single cells and entire cell sheets, tissues or organisms respond to curvature by modulating their shape and their migration behavior. Finally, the interplay between the distribution of morphogens or micro-organisms and the emergence of curvature across length scales is addressed with examples demonstrating these key mechanistic principles of morphogenesis. Overall, this review highlights that curved interfaces are not merely a passive by-product of the chemical, biological, and mechanical processes but that curvature acts also as a signal that co-determines these processes.","lang":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"2206110","file_date_updated":"2023-09-26T10:51:56Z","date_created":"2023-03-05T23:01:06Z","date_updated":"2023-09-26T10:56:46Z","department":[{"_id":"EdHa"}],"intvolume":"        35","article_type":"review","month":"03","acknowledgement":"B.S. and A.R. contributed equally to this work. A.P.G.C. and P.R.F. acknowledge the funding from Fundação para a Ciência e Tecnologia (Portugal), through IDMEC, under LAETA project UIDB/50022/2020. T.H.V.P. acknowledges the funding from Fundação para a Ciência e Tecnologia (Portugal), through Ph.D. Grant 2020.04417.BD. A.S. acknowledges that this work was partially supported by the ATTRACT Investigator Grant (no. A17/MS/11572821/MBRACE, to A.S.) from the Luxembourg National Research Fund. The author thanks Gerardo Ceada for his help in the graphical representations. N.A.K. acknowledges support from the European Research Council (grant 851960) and the Gravitation Program “Materials Driven Regeneration,” funded by the Netherlands Organization for Scientific Research (024.003.013). M.B.A. acknowledges support from the French National Research Agency (grant ANR-201-8-CE1-3-0008 for the project “Epimorph”). G.E.S.T. acknowledges funding by the Australian Research Council through project DP200102593. A.C. acknowledges the funding from the Deutsche Forschungsgemeinschaft (DFG) Emmy Noether Grant CI 203/-2 1, the Spanish Ministry of Science and Innovation (PID2021-123013O-BI00) and the IKERBASQUE Basque Foundation for Science.","citation":{"ista":"Schamberger B, Ziege R, Anselme K, Ben Amar M, Bykowski M, Castro APG, Cipitria A, Coles RA, Dimova R, Eder M, Ehrig S, Escudero LM, Evans ME, Fernandes PR, Fratzl P, Geris L, Gierlinger N, Hannezo EB, Iglič A, Kirkensgaard JJK, Kollmannsberger P, Kowalewska Ł, Kurniawan NA, Papantoniou I, Pieuchot L, Pires THV, Renner LD, Sageman-Furnas AO, Schröder-Turk GE, Sengupta A, Sharma VR, Tagua A, Tomba C, Trepat X, Waters SL, Yeo EF, Roschger A, Bidan CM, Dunlop JWC. 2023. Curvature in biological systems: Its quantification, emergence, and implications across the scales. Advanced Materials. 35(13), 2206110.","ama":"Schamberger B, Ziege R, Anselme K, et al. Curvature in biological systems: Its quantification, emergence, and implications across the scales. <i>Advanced Materials</i>. 2023;35(13). doi:<a href=\"https://doi.org/10.1002/adma.202206110\">10.1002/adma.202206110</a>","apa":"Schamberger, B., Ziege, R., Anselme, K., Ben Amar, M., Bykowski, M., Castro, A. P. G., … Dunlop, J. W. C. (2023). Curvature in biological systems: Its quantification, emergence, and implications across the scales. <i>Advanced Materials</i>. Wiley. <a href=\"https://doi.org/10.1002/adma.202206110\">https://doi.org/10.1002/adma.202206110</a>","short":"B. Schamberger, R. Ziege, K. Anselme, M. Ben Amar, M. Bykowski, A.P.G. Castro, A. Cipitria, R.A. Coles, R. Dimova, M. Eder, S. Ehrig, L.M. Escudero, M.E. Evans, P.R. Fernandes, P. Fratzl, L. Geris, N. Gierlinger, E.B. Hannezo, A. Iglič, J.J.K. Kirkensgaard, P. Kollmannsberger, Ł. Kowalewska, N.A. Kurniawan, I. Papantoniou, L. Pieuchot, T.H.V. Pires, L.D. Renner, A.O. Sageman-Furnas, G.E. Schröder-Turk, A. Sengupta, V.R. Sharma, A. Tagua, C. Tomba, X. Trepat, S.L. Waters, E.F. Yeo, A. Roschger, C.M. Bidan, J.W.C. Dunlop, Advanced Materials 35 (2023).","mla":"Schamberger, Barbara, et al. “Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales.” <i>Advanced Materials</i>, vol. 35, no. 13, 2206110, Wiley, 2023, doi:<a href=\"https://doi.org/10.1002/adma.202206110\">10.1002/adma.202206110</a>.","ieee":"B. Schamberger <i>et al.</i>, “Curvature in biological systems: Its quantification, emergence, and implications across the scales,” <i>Advanced Materials</i>, vol. 35, no. 13. Wiley, 2023.","chicago":"Schamberger, Barbara, Ricardo Ziege, Karine Anselme, Martine Ben Amar, Michał Bykowski, André P.G. Castro, Amaia Cipitria, et al. “Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales.” <i>Advanced Materials</i>. Wiley, 2023. <a href=\"https://doi.org/10.1002/adma.202206110\">https://doi.org/10.1002/adma.202206110</a>."},"issue":"13","_id":"12710","volume":35,"file":[{"date_created":"2023-09-26T10:51:56Z","date_updated":"2023-09-26T10:51:56Z","access_level":"open_access","relation":"main_file","checksum":"5c04d68130e97a0ecd1ca27fbc15a246","file_id":"14373","success":1,"content_type":"application/pdf","creator":"dernst","file_name":"2023_AdvancedMaterials_Schamberger.pdf","file_size":2898063}],"doi":"10.1002/adma.202206110","date_published":"2023-03-29T00:00:00Z","title":"Curvature in biological systems: Its quantification, emergence, and implications across the scales","day":"29","isi":1,"publication":"Advanced Materials","type":"journal_article","publication_status":"published","scopus_import":"1","quality_controlled":"1","publisher":"Wiley","has_accepted_license":"1"},{"ddc":["599","573"],"oa":1,"language":[{"iso":"eng"}],"degree_awarded":"PhD","file_date_updated":"2023-03-08T15:08:46Z","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"CampIT"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","abstract":[{"text":"The process of detecting and evaluating sensory information to guide behaviour is termed perceptual decision-making (PDM), and is critical for the ability of an organism to interact with its external world. Individuals with autism, a neurodevelopmental condition primarily characterised by social and communication difficulties, frequently exhibit altered sensory processing and PDM difficulties are widely reported. Recent technological advancements have pushed forward our understanding of the genetic changes accompanying this condition, however our understanding of how these mutations affect the function of specific neuronal circuits and bring about the corresponding behavioural changes remains limited. Here, we use an innate PDM task, the looming avoidance response (LAR) paradigm, to identify a convergent behavioural abnormality across three molecularly distinct genetic mouse models of autism (Cul3, Setd5 and Ptchd1). Although mutant mice can rapidly detect threatening visual stimuli, their responses are consistently delayed, requiring longer to initiate an appropriate response than their wild-type siblings. Mutant animals show abnormal adaptation in both their stimulus- evoked escape responses and exploratory dynamics following repeated stimulus presentations. Similarly delayed behavioural responses are observed in wild-type animals when faced with more ambiguous threats, suggesting the mutant phenotype could arise from a dysfunction in the flexible control of this PDM process.\r\nOur knowledge of the core neuronal circuitry mediating the LAR facilitated a detailed dissection of the neuronal mechanisms underlying the behavioural impairment. In vivo extracellular recording revealed that visual responses were unaffected within a key brain region for the rapid processing of visual threats, the superior colliculus (SC), indicating that the behavioural delay was unlikely to originate from sensory impairments. Delayed behavioural responses were recapitulated in the Setd5 model following optogenetic stimulation of the excitatory output neurons of the SC, which are known to mediate escape initiation through the activation of cells in the underlying dorsal periaqueductal grey (dPAG). In vitro patch-clamp recordings of dPAG cells uncovered a stark hypoexcitability phenotype in two out of the three genetic models investigated (Setd5 and Ptchd1), that in Setd5, is mediated by the misregulation of voltage-gated potassium channels. Overall, our results show that the ability to use visual information to drive efficient escape responses is impaired in three diverse genetic mouse models of autism and that, in one of the models studied, this behavioural delay likely originates from differences in the intrinsic excitability of a key subcortical node, the dPAG. Furthermore, this work showcases the use of an innate behavioural paradigm to mechanistically dissect PDM processes in autism.","lang":"eng"}],"article_processing_charge":"No","author":[{"first_name":"Laura","id":"3B717F68-F248-11E8-B48F-1D18A9856A87","last_name":"Burnett","full_name":"Burnett, Laura","orcid":"0000-0002-8937-410X"}],"page":"178","oa_version":"Published Version","status":"public","ec_funded":1,"publication_identifier":{"issn":["2663-337X"]},"year":"2023","day":"10","date_published":"2023-03-10T00:00:00Z","title":"To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism","alternative_title":["ISTA Thesis"],"has_accepted_license":"1","publication_status":"published","type":"dissertation","publisher":"Institute of Science and Technology Austria","month":"03","citation":{"short":"L. Burnett, To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism, Institute of Science and Technology Austria, 2023.","mla":"Burnett, Laura. <i>To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12716\">10.15479/at:ista:12716</a>.","ieee":"L. Burnett, “To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism,” Institute of Science and Technology Austria, 2023.","chicago":"Burnett, Laura. “To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12716\">https://doi.org/10.15479/at:ista:12716</a>.","ista":"Burnett L. 2023. To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism. Institute of Science and Technology Austria.","ama":"Burnett L. To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12716\">10.15479/at:ista:12716</a>","apa":"Burnett, L. (2023). <i>To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12716\">https://doi.org/10.15479/at:ista:12716</a>"},"department":[{"_id":"GradSch"},{"_id":"MaJö"}],"date_updated":"2023-04-05T10:59:04Z","date_created":"2023-03-08T15:19:45Z","file":[{"checksum":"6c6d9cc2c4cdacb74e6b1047a34d7332","file_id":"12717","date_updated":"2023-03-08T15:08:46Z","access_level":"closed","relation":"source_file","date_created":"2023-03-08T15:08:46Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","creator":"lburnett","file_size":23029260,"file_name":"Burnett_Thesis_2023.docx"},{"success":1,"checksum":"cebc77705288bf4382db9b3541483cd0","file_id":"12718","access_level":"open_access","date_updated":"2023-03-08T15:08:46Z","date_created":"2023-03-08T15:08:46Z","relation":"main_file","content_type":"application/pdf","creator":"lburnett","file_size":11959869,"file_name":"Burnett_Thesis_2023_pdfA.pdf"}],"supervisor":[{"last_name":"Jösch","full_name":"Jösch, Maximilian A","orcid":"0000-0002-3937-1330","first_name":"Maximilian A","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87"}],"doi":"10.15479/at:ista:12716","project":[{"grant_number":"756502","name":"Circuits of Visual Attention","call_identifier":"H2020","_id":"2634E9D2-B435-11E9-9278-68D0E5697425"}],"_id":"12716"}]