---
_id: '10829'
abstract:
- lang: eng
  text: A novel multivariable system, combining a transistor with fiber optic-based
    surface plasmon resonance spectroscopy with the gate electrode simultaneously
    acting as the fiber optic sensor surface, is reported. The dual-mode sensor allows
    for discrimination of mass and charge contributions for binding assays on the
    same sensor surface. Furthermore, we optimize the sensor geometry by investigating
    the influence of the fiber area to transistor channel area ratio and distance.
    We show that larger fiber optic tip diameters are favorable for electronic and
    optical signals and demonstrate the reversibility of plasmon resonance wavelength
    shifts after electric field application. As a proof of principle, a layer-by-layer
    assembly of polyelectrolytes is performed to benchmark the system against multivariable
    sensing platforms with planar surface plasmon resonance configurations. Furthermore,
    the biosensing performance is assessed using a thrombin binding assay with surface-immobilized
    aptamers as receptors, allowing for the detection of medically relevant thrombin
    concentrations.
acknowledgement: "This project has received funding from the European Union’s Horizon
  2020 Research and Innovation Programme under the Marie Skłodowska-Curie grant agreement
  No. 813863-\r\nBORGES. Additionally, we gratefully acknowledge the financial support
  from the Austrian Research Promotion Agency (FFG; 870025 and 873541) for this research.
  The data that support the findings of this study are openly available in Zenodo
  (DOI: 10.5281/zenodo.5500360)"
article_processing_charge: No
article_type: original
author:
- first_name: Roger
  full_name: Hasler, Roger
  last_name: Hasler
- first_name: Ciril
  full_name: Reiner-Rozman, Ciril
  last_name: Reiner-Rozman
- first_name: Stefan
  full_name: Fossati, Stefan
  last_name: Fossati
- first_name: Patrik
  full_name: Aspermair, Patrik
  last_name: Aspermair
- first_name: Jakub
  full_name: Dostalek, Jakub
  last_name: Dostalek
- first_name: Seungho
  full_name: Lee, Seungho
  id: BB243B88-D767-11E9-B658-BC13E6697425
  last_name: Lee
  orcid: 0000-0002-6962-8598
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Johannes
  full_name: Bintinger, Johannes
  last_name: Bintinger
- first_name: Wolfgang
  full_name: Knoll, Wolfgang
  last_name: Knoll
citation:
  ama: Hasler R, Reiner-Rozman C, Fossati S, et al. Field-effect transistor with a
    plasmonic fiber optic gate electrode as a multivariable biosensor device. <i>ACS
    Sensors</i>. 2022;7(2):504-512. doi:<a href="https://doi.org/10.1021/acssensors.1c02313">10.1021/acssensors.1c02313</a>
  apa: Hasler, R., Reiner-Rozman, C., Fossati, S., Aspermair, P., Dostalek, J., Lee,
    S., … Knoll, W. (2022). Field-effect transistor with a plasmonic fiber optic gate
    electrode as a multivariable biosensor device. <i>ACS Sensors</i>. American Chemical
    Society. <a href="https://doi.org/10.1021/acssensors.1c02313">https://doi.org/10.1021/acssensors.1c02313</a>
  chicago: Hasler, Roger, Ciril Reiner-Rozman, Stefan Fossati, Patrik Aspermair, Jakub
    Dostalek, Seungho Lee, Maria Ibáñez, Johannes Bintinger, and Wolfgang Knoll. “Field-Effect
    Transistor with a Plasmonic Fiber Optic Gate Electrode as a Multivariable Biosensor
    Device.” <i>ACS Sensors</i>. American Chemical Society, 2022. <a href="https://doi.org/10.1021/acssensors.1c02313">https://doi.org/10.1021/acssensors.1c02313</a>.
  ieee: R. Hasler <i>et al.</i>, “Field-effect transistor with a plasmonic fiber optic
    gate electrode as a multivariable biosensor device,” <i>ACS Sensors</i>, vol.
    7, no. 2. American Chemical Society, pp. 504–512, 2022.
  ista: Hasler R, Reiner-Rozman C, Fossati S, Aspermair P, Dostalek J, Lee S, Ibáñez
    M, Bintinger J, Knoll W. 2022. Field-effect transistor with a plasmonic fiber
    optic gate electrode as a multivariable biosensor device. ACS Sensors. 7(2), 504–512.
  mla: Hasler, Roger, et al. “Field-Effect Transistor with a Plasmonic Fiber Optic
    Gate Electrode as a Multivariable Biosensor Device.” <i>ACS Sensors</i>, vol.
    7, no. 2, American Chemical Society, 2022, pp. 504–12, doi:<a href="https://doi.org/10.1021/acssensors.1c02313">10.1021/acssensors.1c02313</a>.
  short: R. Hasler, C. Reiner-Rozman, S. Fossati, P. Aspermair, J. Dostalek, S. Lee,
    M. Ibáñez, J. Bintinger, W. Knoll, ACS Sensors 7 (2022) 504–512.
date_created: 2022-03-06T23:01:54Z
date_published: 2022-02-08T00:00:00Z
date_updated: 2023-08-02T14:46:17Z
day: '08'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1021/acssensors.1c02313
external_id:
  isi:
  - '000765113000016'
file:
- access_level: open_access
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  creator: dernst
  date_created: 2022-03-07T08:15:01Z
  date_updated: 2022-03-07T08:15:01Z
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file_date_updated: 2022-03-07T08:15:01Z
has_accepted_license: '1'
intvolume: '         7'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 504-512
publication: ACS Sensors
publication_identifier:
  eissn:
  - '23793694'
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
related_material:
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    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Field-effect transistor with a plasmonic fiber optic gate electrode as a multivariable
  biosensor device
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 7
year: '2022'
...