---
_id: '15047'
abstract:
- lang: eng
  text: Tropical precipitation extremes and their changes with surface warming are
    investigated using global storm resolving simulations and high-resolution observations.
    The simulations demonstrate that the mesoscale organization of convection, a process
    that cannot be physically represented by conventional global climate models, is
    important for the variations of tropical daily accumulated precipitation extremes.
    In both the simulations and observations, daily precipitation extremes increase
    in a more organized state, in association with larger, but less frequent, storms.
    Repeating the simulations for a warmer climate results in a robust increase in
    monthly-mean daily precipitation extremes. Higher precipitation percentiles have
    a greater sensitivity to convective organization, which is predicted to increase
    with warming. Without changes in organization, the strongest daily precipitation
    extremes over the tropical oceans increase at a rate close to Clausius-Clapeyron
    (CC) scaling. Thus, in a future warmer state with increased organization, the
    strongest daily precipitation extremes over oceans increase at a faster rate than
    CC scaling.
acknowledgement: This work is supported by the Max-Planck-Gesellschaft (MPG). We greatly
  appreciate computational resources from Deutsches Klimarechenzentrum (DKRZ) and
  the Jülich Supercomputing Centre (JSC). ICONA/O simulations are funded through the
  NextGEMS project by the EU’s Horizon 2020 programme (grant agreement no. 101003470).
  ICONA simulations are funded through the MONSOON-2.0 project (grant agreement no.
  01LP1927A) which is supported from German Federal Ministry of Education and Research
  (BMBF). J.B. acknowledges funding from the European Union’s Horizon 2020 research
  and innovation programme under the Marie Skłodowska-Curie grant (grant agreement
  no. 101034413). B.S. acknowledges funding from the EU’s Horizon 2020 programme (grant
  agreement no. 101003470). C.M. gratefully acknowledges funding from the European
  Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
  program (Project CLUSTER, grant agreement no. 805041).
article_number: eadj6801
article_processing_charge: Yes
article_type: original
author:
- first_name: Jiawei
  full_name: Bao, Jiawei
  id: bb9a7399-fefd-11ed-be3c-ae648fd1d160
  last_name: Bao
- first_name: Bjorn
  full_name: Stevens, Bjorn
  last_name: Stevens
- first_name: Lukas
  full_name: Kluft, Lukas
  last_name: Kluft
- first_name: Caroline J
  full_name: Muller, Caroline J
  id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
  last_name: Muller
  orcid: 0000-0001-5836-5350
citation:
  ama: Bao J, Stevens B, Kluft L, Muller CJ. Intensification of daily tropical precipitation
    extremes from more organized convection. <i>Science Advances</i>. 2024;10(8).
    doi:<a href="https://doi.org/10.1126/sciadv.adj6801">10.1126/sciadv.adj6801</a>
  apa: Bao, J., Stevens, B., Kluft, L., &#38; Muller, C. J. (2024). Intensification
    of daily tropical precipitation extremes from more organized convection. <i>Science
    Advances</i>. American Association for the Advancement of Science. <a href="https://doi.org/10.1126/sciadv.adj6801">https://doi.org/10.1126/sciadv.adj6801</a>
  chicago: Bao, Jiawei, Bjorn Stevens, Lukas Kluft, and Caroline J Muller. “Intensification
    of Daily Tropical Precipitation Extremes from More Organized Convection.” <i>Science
    Advances</i>. American Association for the Advancement of Science, 2024. <a href="https://doi.org/10.1126/sciadv.adj6801">https://doi.org/10.1126/sciadv.adj6801</a>.
  ieee: J. Bao, B. Stevens, L. Kluft, and C. J. Muller, “Intensification of daily
    tropical precipitation extremes from more organized convection,” <i>Science Advances</i>,
    vol. 10, no. 8. American Association for the Advancement of Science, 2024.
  ista: Bao J, Stevens B, Kluft L, Muller CJ. 2024. Intensification of daily tropical
    precipitation extremes from more organized convection. Science Advances. 10(8),
    eadj6801.
  mla: Bao, Jiawei, et al. “Intensification of Daily Tropical Precipitation Extremes
    from More Organized Convection.” <i>Science Advances</i>, vol. 10, no. 8, eadj6801,
    American Association for the Advancement of Science, 2024, doi:<a href="https://doi.org/10.1126/sciadv.adj6801">10.1126/sciadv.adj6801</a>.
  short: J. Bao, B. Stevens, L. Kluft, C.J. Muller, Science Advances 10 (2024).
date_created: 2024-03-03T23:00:50Z
date_published: 2024-02-23T00:00:00Z
date_updated: 2024-03-05T09:26:47Z
day: '23'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1126/sciadv.adj6801
ec_funded: 1
external_id:
  pmid:
  - '38394192'
file:
- access_level: open_access
  checksum: d4ec4f05a6d14745057e14d1b8bf45ae
  content_type: application/pdf
  creator: dernst
  date_created: 2024-03-04T07:34:00Z
  date_updated: 2024-03-04T07:34:00Z
  file_id: '15051'
  file_name: 2024_ScienceAdv_Bao.pdf
  file_size: 800926
  relation: main_file
  success: 1
file_date_updated: 2024-03-04T07:34:00Z
has_accepted_license: '1'
intvolume: '        10'
issue: '8'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: 629205d8-2b32-11ec-9570-e1356ff73576
  call_identifier: H2020
  grant_number: '805041'
  name: organization of CLoUdS, and implications of Tropical  cyclones and for the
    Energetics of the tropics, in current and waRming climate
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA Website
    relation: press_release
    url: https://ista.ac.at/en/news/cloud-clustering-causes-more-extreme-rain/
scopus_import: '1'
status: public
title: Intensification of daily tropical precipitation extremes from more organized
  convection
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2024'
...
---
_id: '13259'
abstract:
- lang: eng
  text: Plants can regenerate their bodies via de novo establishment of shoot apical
    meristems (SAMs) from pluripotent callus. Only a small fraction of callus cells
    is eventually specified into SAMs but the molecular mechanisms underlying fate
    specification remain obscure. The expression of WUSCHEL (WUS) is an early hallmark
    of SAM fate acquisition. Here, we show that a WUS paralog, WUSCHEL-RELATED HOMEOBOX
    13 (WOX13), negatively regulates SAM formation from callus in Arabidopsis thaliana.
    WOX13 promotes non-meristematic cell fate via transcriptional repression of WUS
    and other SAM regulators and activation of cell wall modifiers. Our Quartz-Seq2–based
    single cell transcriptome revealed that WOX13 plays key roles in determining cellular
    identity of callus cell population. We propose that reciprocal inhibition between
    WUS and WOX13 mediates critical cell fate determination in pluripotent cell population,
    which has a major impact on regeneration efficiency.
acknowledgement: Wethank Y.Iwayama, K.Ohtawa, K.Fukumoto,andN. Mataga (RIKENRRD) for
  technical assistance in Quartz-Seq2analyses; M. Mouri(RIKENCSRS)for technical support
  with plasmid construction and transactivation assay; Y. Ikeda (NAIST) for technical
  support with tissue culture; and A. Furuta for technical support in bulk RNA-seq
  analysis. We also thank the Single-cell Omics Laboratory for technical consultation
  in scRNA-seq analyses, the members of the Laboratory for Bioinformatics Research
  at the RIKEN Center for Biosystems Dynamics Research, and A. Matsushima and T. Ichikawa
  for IT infrastructure management. This work was supported by JSPS KAKENHI(17K15146,19H05670,20K06712,20H04894,20H05431,and
  22H04713 to M.I. and 20H03284 and 20H05911 to K.S.), by the JST FOREST Program (JPMJFR214H
  to M.I.), by The Naito Foundation to M.I.; by Takeda Science Foundation to M.I,and
  by the Shiseido Female Researcher Science Grant to M.I. This work was partially
  supported by RIKENE pigenome Control Program, Medical Research Center Initiative
  for High Depth Omics, and JST CREST(JPMJCR16G3and JPMJCR1926)to I.N.
article_processing_charge: Yes
article_type: original
author:
- first_name: Nao
  full_name: Ogura, Nao
  last_name: Ogura
- first_name: Yohei
  full_name: Sasagawa, Yohei
  last_name: Sasagawa
- first_name: Tasuku
  full_name: Ito, Tasuku
  id: d5a17a4a-e534-11eb-93ec-91fa2aa9bd57
  last_name: Ito
  orcid: 0000-0002-2482-9089
- first_name: Toshiaki
  full_name: Tameshige, Toshiaki
  last_name: Tameshige
- first_name: Satomi
  full_name: Kawai, Satomi
  last_name: Kawai
- first_name: Masaki
  full_name: Sano, Masaki
  last_name: Sano
- first_name: Yuki
  full_name: Doll, Yuki
  last_name: Doll
- first_name: Akira
  full_name: Iwase, Akira
  last_name: Iwase
- first_name: Ayako
  full_name: Kawamura, Ayako
  last_name: Kawamura
- first_name: Takamasa
  full_name: Suzuki, Takamasa
  last_name: Suzuki
- first_name: Itoshi
  full_name: Nikaido, Itoshi
  last_name: Nikaido
- first_name: Keiko
  full_name: Sugimoto, Keiko
  last_name: Sugimoto
- first_name: Momoko
  full_name: Ikeuchi, Momoko
  last_name: Ikeuchi
citation:
  ama: Ogura N, Sasagawa Y, Ito T, et al. WUSCHEL-RELATED HOMEOBOX 13 suppresses de
    novo shoot regeneration via cell fate control of pluripotent callus. <i>Science
    Advances</i>. 2023;9(27):eadg6983. doi:<a href="https://doi.org/10.1126/sciadv.adg6983">10.1126/sciadv.adg6983</a>
  apa: Ogura, N., Sasagawa, Y., Ito, T., Tameshige, T., Kawai, S., Sano, M., … Ikeuchi,
    M. (2023). WUSCHEL-RELATED HOMEOBOX 13 suppresses de novo shoot regeneration via
    cell fate control of pluripotent callus. <i>Science Advances</i>. American Association
    for the Advancement of Science. <a href="https://doi.org/10.1126/sciadv.adg6983">https://doi.org/10.1126/sciadv.adg6983</a>
  chicago: Ogura, Nao, Yohei Sasagawa, Tasuku Ito, Toshiaki Tameshige, Satomi Kawai,
    Masaki Sano, Yuki Doll, et al. “WUSCHEL-RELATED HOMEOBOX 13 Suppresses de Novo
    Shoot Regeneration via Cell Fate Control of Pluripotent Callus.” <i>Science Advances</i>.
    American Association for the Advancement of Science, 2023. <a href="https://doi.org/10.1126/sciadv.adg6983">https://doi.org/10.1126/sciadv.adg6983</a>.
  ieee: N. Ogura <i>et al.</i>, “WUSCHEL-RELATED HOMEOBOX 13 suppresses de novo shoot
    regeneration via cell fate control of pluripotent callus,” <i>Science Advances</i>,
    vol. 9, no. 27. American Association for the Advancement of Science, p. eadg6983,
    2023.
  ista: Ogura N, Sasagawa Y, Ito T, Tameshige T, Kawai S, Sano M, Doll Y, Iwase A,
    Kawamura A, Suzuki T, Nikaido I, Sugimoto K, Ikeuchi M. 2023. WUSCHEL-RELATED
    HOMEOBOX 13 suppresses de novo shoot regeneration via cell fate control of pluripotent
    callus. Science Advances. 9(27), eadg6983.
  mla: Ogura, Nao, et al. “WUSCHEL-RELATED HOMEOBOX 13 Suppresses de Novo Shoot Regeneration
    via Cell Fate Control of Pluripotent Callus.” <i>Science Advances</i>, vol. 9,
    no. 27, American Association for the Advancement of Science, 2023, p. eadg6983,
    doi:<a href="https://doi.org/10.1126/sciadv.adg6983">10.1126/sciadv.adg6983</a>.
  short: N. Ogura, Y. Sasagawa, T. Ito, T. Tameshige, S. Kawai, M. Sano, Y. Doll,
    A. Iwase, A. Kawamura, T. Suzuki, I. Nikaido, K. Sugimoto, M. Ikeuchi, Science
    Advances 9 (2023) eadg6983.
date_created: 2023-07-23T22:01:11Z
date_published: 2023-07-07T00:00:00Z
date_updated: 2023-12-13T11:59:29Z
day: '07'
ddc:
- '580'
doi: 10.1126/sciadv.adg6983
external_id:
  isi:
  - '001030983100012'
  pmid:
  - '37418524'
file:
- access_level: open_access
  checksum: f59217e1083767777318b5d0cc5e141d
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-01T06:40:35Z
  date_updated: 2023-08-01T06:40:35Z
  file_id: '13338'
  file_name: 2023_ScienceAdvance_Ogura.pdf
  file_size: 1759993
  relation: main_file
  success: 1
file_date_updated: 2023-08-01T06:40:35Z
has_accepted_license: '1'
intvolume: '         9'
isi: 1
issue: '27'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: eadg6983
pmid: 1
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: WUSCHEL-RELATED HOMEOBOX 13 suppresses de novo shoot regeneration via cell
  fate control of pluripotent callus
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2023'
...
---
_id: '12756'
abstract:
- lang: eng
  text: ESCRT-III family proteins form composite polymers that deform and cut membrane
    tubes in the context of a wide range of cell biological processes across the tree
    of life. In reconstituted systems, sequential changes in the composition of ESCRT-III
    polymers induced by the AAA–adenosine triphosphatase Vps4 have been shown to remodel
    membranes. However, it is not known how composite ESCRT-III polymers are organized
    and remodeled in space and time in a cellular context. Taking advantage of the
    relative simplicity of the ESCRT-III–dependent division system in Sulfolobus acidocaldarius,
    one of the closest experimentally tractable prokaryotic relatives of eukaryotes,
    we use super-resolution microscopy, electron microscopy, and computational modeling
    to show how CdvB/CdvB1/CdvB2 proteins form a precisely patterned composite ESCRT-III
    division ring, which undergoes stepwise Vps4-dependent disassembly and contracts
    to cut cells into two. These observations lead us to suggest sequential changes
    in a patterned composite polymer as a general mechanism of ESCRT-III–dependent
    membrane remodeling.
acknowledgement: "We thank Y. Liu and V. Hale for help with electron cryotomography;
  the Medical Research Council (MRC) LMB Electron Microscopy Facility for access,
  training, and support; and T. Darling and J. Grimmett at the MRC LMB for help with
  computing infrastructure. We also thank the Flow Cytometry Facility and the MRC
  LMB for training and support.\r\n F.H. and G.T.-R. were supported by a grant from
  the Wellcome Trust (203276/Z/16/Z). A.C. was supported by an EMBO long-term fellowship:
  ALTF_1041-2021. J.T. was supported by a grant from the VW Foundation (94933). A.A.P.
  was supported by the Wellcome Trust (203276/Z/16/Z) and the HFSP (LT001027/2019).
  B.B. received support from the MRC LMB, the Wellcome Trust (203276/Z/16/Z), the
  VW Foundation (94933), the Life Sciences–Moore-Simons Foundation (735929LPI), and
  a Gordon and Betty Moore Foundation’s Symbiosis in Aquatic Systems Initiative (9346).
  A.Š. and X.J. acknowledge funding from the European Research Council (ERC) under
  the European Union’s Horizon 2020 research and innovation programme (grant no. 802960).
  L.H.-K. acknowledges support from Biotechnology and Biological Sciences Research
  Council LIDo Programme. T.N. and J.L. were supported by the MRC (U105184326) and
  the Wellcome Trust (203276/Z/16/Z)."
article_number: eade5224
article_processing_charge: No
article_type: original
author:
- first_name: Fredrik
  full_name: Hurtig, Fredrik
  last_name: Hurtig
- first_name: Thomas C.Q.
  full_name: Burgers, Thomas C.Q.
  last_name: Burgers
- first_name: Alice
  full_name: Cezanne, Alice
  last_name: Cezanne
- first_name: Xiuyun
  full_name: Jiang, Xiuyun
  last_name: Jiang
- first_name: Frank N.
  full_name: Mol, Frank N.
  last_name: Mol
- first_name: Jovan
  full_name: Traparić, Jovan
  last_name: Traparić
- first_name: Andre Arashiro
  full_name: Pulschen, Andre Arashiro
  last_name: Pulschen
- first_name: Tim
  full_name: Nierhaus, Tim
  last_name: Nierhaus
- first_name: Gabriel
  full_name: Tarrason-Risa, Gabriel
  last_name: Tarrason-Risa
- first_name: Lena
  full_name: Harker-Kirschneck, Lena
  last_name: Harker-Kirschneck
- first_name: Jan
  full_name: Löwe, Jan
  last_name: Löwe
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
- first_name: Rifka
  full_name: Vlijm, Rifka
  last_name: Vlijm
- first_name: Buzz
  full_name: Baum, Buzz
  last_name: Baum
citation:
  ama: Hurtig F, Burgers TCQ, Cezanne A, et al. The patterned assembly and stepwise
    Vps4-mediated disassembly of composite ESCRT-III polymers drives archaeal cell
    division. <i>Science Advances</i>. 2023;9(11). doi:<a href="https://doi.org/10.1126/sciadv.ade5224">10.1126/sciadv.ade5224</a>
  apa: Hurtig, F., Burgers, T. C. Q., Cezanne, A., Jiang, X., Mol, F. N., Traparić,
    J., … Baum, B. (2023). The patterned assembly and stepwise Vps4-mediated disassembly
    of composite ESCRT-III polymers drives archaeal cell division. <i>Science Advances</i>.
    American Association for the Advancement of Science. <a href="https://doi.org/10.1126/sciadv.ade5224">https://doi.org/10.1126/sciadv.ade5224</a>
  chicago: Hurtig, Fredrik, Thomas C.Q. Burgers, Alice Cezanne, Xiuyun Jiang, Frank
    N. Mol, Jovan Traparić, Andre Arashiro Pulschen, et al. “The Patterned Assembly
    and Stepwise Vps4-Mediated Disassembly of Composite ESCRT-III Polymers Drives
    Archaeal Cell Division.” <i>Science Advances</i>. American Association for the
    Advancement of Science, 2023. <a href="https://doi.org/10.1126/sciadv.ade5224">https://doi.org/10.1126/sciadv.ade5224</a>.
  ieee: F. Hurtig <i>et al.</i>, “The patterned assembly and stepwise Vps4-mediated
    disassembly of composite ESCRT-III polymers drives archaeal cell division,” <i>Science
    Advances</i>, vol. 9, no. 11. American Association for the Advancement of Science,
    2023.
  ista: Hurtig F, Burgers TCQ, Cezanne A, Jiang X, Mol FN, Traparić J, Pulschen AA,
    Nierhaus T, Tarrason-Risa G, Harker-Kirschneck L, Löwe J, Šarić A, Vlijm R, Baum
    B. 2023. The patterned assembly and stepwise Vps4-mediated disassembly of composite
    ESCRT-III polymers drives archaeal cell division. Science Advances. 9(11), eade5224.
  mla: Hurtig, Fredrik, et al. “The Patterned Assembly and Stepwise Vps4-Mediated
    Disassembly of Composite ESCRT-III Polymers Drives Archaeal Cell Division.” <i>Science
    Advances</i>, vol. 9, no. 11, eade5224, American Association for the Advancement
    of Science, 2023, doi:<a href="https://doi.org/10.1126/sciadv.ade5224">10.1126/sciadv.ade5224</a>.
  short: F. Hurtig, T.C.Q. Burgers, A. Cezanne, X. Jiang, F.N. Mol, J. Traparić, A.A.
    Pulschen, T. Nierhaus, G. Tarrason-Risa, L. Harker-Kirschneck, J. Löwe, A. Šarić,
    R. Vlijm, B. Baum, Science Advances 9 (2023).
date_created: 2023-03-26T22:01:06Z
date_published: 2023-03-17T00:00:00Z
date_updated: 2023-08-01T13:45:54Z
day: '17'
ddc:
- '570'
department:
- _id: AnSa
doi: 10.1126/sciadv.ade5224
ec_funded: 1
external_id:
  isi:
  - '000968083500010'
file:
- access_level: open_access
  checksum: 6d7dbe9ed86a116c8a002d62971202c5
  content_type: application/pdf
  creator: dernst
  date_created: 2023-03-27T06:24:49Z
  date_updated: 2023-03-27T06:24:49Z
  file_id: '12768'
  file_name: 2023_ScienceAdvances_Hurtig.pdf
  file_size: 1826471
  relation: main_file
  success: 1
file_date_updated: 2023-03-27T06:24:49Z
has_accepted_license: '1'
intvolume: '         9'
isi: 1
issue: '11'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: eba2549b-77a9-11ec-83b8-a81e493eae4e
  call_identifier: H2020
  grant_number: '802960'
  name: 'Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines'
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: The patterned assembly and stepwise Vps4-mediated disassembly of composite
  ESCRT-III polymers drives archaeal cell division
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2023'
...
---
_id: '13992'
abstract:
- lang: eng
  text: Understanding the chirality of molecular reaction pathways is essential for
    a broad range of fundamental and applied sciences. However, the current ability
    to probe chirality on the time scale of primary processes underlying chemical
    reactions remains very limited. Here, we demonstrate time-resolved photoelectron
    circular dichroism (TRPECD) with ultrashort circularly polarized vacuum-ultraviolet
    (VUV) pulses from a tabletop source. We demonstrate the capabilities of VUV-TRPECD
    by resolving the chirality changes in time during the photodissociation of atomic
    iodine from two chiral molecules. We identify several general key features of
    TRPECD, which include the ability to probe dynamical chirality along the complete
    photochemical reaction path, the sensitivity to the local chirality of the evolving
    scattering potential, and the influence of electron scattering off dissociating
    photofragments. Our results are interpreted by comparison with high-level ab-initio
    calculations of transient PECDs from molecular photoionization calculations. Our
    experimental and theoretical techniques define a general approach to femtochirality.
article_number: abq2811
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Vít
  full_name: Svoboda, Vít
  last_name: Svoboda
- first_name: Niraghatam Bhargava
  full_name: Ram, Niraghatam Bhargava
  last_name: Ram
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Daniel
  full_name: Zindel, Daniel
  last_name: Zindel
- first_name: Max D. J.
  full_name: Waters, Max D. J.
  last_name: Waters
- first_name: Benjamin
  full_name: Spenger, Benjamin
  last_name: Spenger
- first_name: Manuel
  full_name: Ochsner, Manuel
  last_name: Ochsner
- first_name: Holger
  full_name: Herburger, Holger
  last_name: Herburger
- first_name: Jürgen
  full_name: Stohner, Jürgen
  last_name: Stohner
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Svoboda V, Ram NB, Baykusheva DR, et al. Femtosecond photoelectron circular
    dichroism of chemical reactions. <i>Science Advances</i>. 2022;8(28). doi:<a href="https://doi.org/10.1126/sciadv.abq2811">10.1126/sciadv.abq2811</a>
  apa: Svoboda, V., Ram, N. B., Baykusheva, D. R., Zindel, D., Waters, M. D. J., Spenger,
    B., … Wörner, H. J. (2022). Femtosecond photoelectron circular dichroism of chemical
    reactions. <i>Science Advances</i>. American Association for the Advancement of
    Science. <a href="https://doi.org/10.1126/sciadv.abq2811">https://doi.org/10.1126/sciadv.abq2811</a>
  chicago: Svoboda, Vít, Niraghatam Bhargava Ram, Denitsa Rangelova Baykusheva, Daniel
    Zindel, Max D. J. Waters, Benjamin Spenger, Manuel Ochsner, Holger Herburger,
    Jürgen Stohner, and Hans Jakob Wörner. “Femtosecond Photoelectron Circular Dichroism
    of Chemical Reactions.” <i>Science Advances</i>. American Association for the
    Advancement of Science, 2022. <a href="https://doi.org/10.1126/sciadv.abq2811">https://doi.org/10.1126/sciadv.abq2811</a>.
  ieee: V. Svoboda <i>et al.</i>, “Femtosecond photoelectron circular dichroism of
    chemical reactions,” <i>Science Advances</i>, vol. 8, no. 28. American Association
    for the Advancement of Science, 2022.
  ista: Svoboda V, Ram NB, Baykusheva DR, Zindel D, Waters MDJ, Spenger B, Ochsner
    M, Herburger H, Stohner J, Wörner HJ. 2022. Femtosecond photoelectron circular
    dichroism of chemical reactions. Science Advances. 8(28), abq2811.
  mla: Svoboda, Vít, et al. “Femtosecond Photoelectron Circular Dichroism of Chemical
    Reactions.” <i>Science Advances</i>, vol. 8, no. 28, abq2811, American Association
    for the Advancement of Science, 2022, doi:<a href="https://doi.org/10.1126/sciadv.abq2811">10.1126/sciadv.abq2811</a>.
  short: V. Svoboda, N.B. Ram, D.R. Baykusheva, D. Zindel, M.D.J. Waters, B. Spenger,
    M. Ochsner, H. Herburger, J. Stohner, H.J. Wörner, Science Advances 8 (2022).
date_created: 2023-08-09T13:08:04Z
date_published: 2022-07-15T00:00:00Z
date_updated: 2023-08-22T07:24:01Z
day: '15'
doi: 10.1126/sciadv.abq2811
extern: '1'
external_id:
  arxiv:
  - '2206.04099'
  pmid:
  - '35857523'
intvolume: '         8'
issue: '28'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1126/sciadv.abq2811
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Femtosecond photoelectron circular dichroism of chemical reactions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2022'
...
---
_id: '13995'
abstract:
- lang: eng
  text: Shape resonances play a central role in many areas of science, but the real-time
    measurement of the associated many-body dynamics remains challenging. Here, we
    present measurements of recoil frame angle-resolved photoionization delays in
    the vicinity of shape resonances of CF4. This technique provides insights into
    the spatiotemporal photoionization dynamics of molecular shape resonances. We
    find delays of up to ∼600 as in the ionization out of the highest occupied molecular
    orbital (HOMO) with a strong dependence on the emission direction and a pronounced
    asymmetry along the dissociation axis. Comparison with quantum-scattering calculations
    traces the asymmetries to the interference of a small subset of partial waves
    at low kinetic energies and, additionally, to the interference of two overlapping
    shape resonances in the HOMO-1 channel. Our experimental and theoretical results
    establish a broadly applicable approach to space- and time-resolved photoionization
    dynamics in the molecular frame.
article_number: abj8121
article_processing_charge: No
article_type: original
author:
- first_name: Saijoscha
  full_name: Heck, Saijoscha
  last_name: Heck
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Meng
  full_name: Han, Meng
  last_name: Han
- first_name: Jia-Bao
  full_name: Ji, Jia-Bao
  last_name: Ji
- first_name: Conaill
  full_name: Perry, Conaill
  last_name: Perry
- first_name: Xiaochun
  full_name: Gong, Xiaochun
  last_name: Gong
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Heck S, Baykusheva DR, Han M, et al. Attosecond interferometry of shape resonances
    in the recoil frame of CF4. <i>Science Advances</i>. 2021;7(49). doi:<a href="https://doi.org/10.1126/sciadv.abj8121">10.1126/sciadv.abj8121</a>
  apa: Heck, S., Baykusheva, D. R., Han, M., Ji, J.-B., Perry, C., Gong, X., &#38;
    Wörner, H. J. (2021). Attosecond interferometry of shape resonances in the recoil
    frame of CF4. <i>Science Advances</i>. American Association for the Advancement
    of Science. <a href="https://doi.org/10.1126/sciadv.abj8121">https://doi.org/10.1126/sciadv.abj8121</a>
  chicago: Heck, Saijoscha, Denitsa Rangelova Baykusheva, Meng Han, Jia-Bao Ji, Conaill
    Perry, Xiaochun Gong, and Hans Jakob Wörner. “Attosecond Interferometry of Shape
    Resonances in the Recoil Frame of CF4.” <i>Science Advances</i>. American Association
    for the Advancement of Science, 2021. <a href="https://doi.org/10.1126/sciadv.abj8121">https://doi.org/10.1126/sciadv.abj8121</a>.
  ieee: S. Heck <i>et al.</i>, “Attosecond interferometry of shape resonances in the
    recoil frame of CF4,” <i>Science Advances</i>, vol. 7, no. 49. American Association
    for the Advancement of Science, 2021.
  ista: Heck S, Baykusheva DR, Han M, Ji J-B, Perry C, Gong X, Wörner HJ. 2021. Attosecond
    interferometry of shape resonances in the recoil frame of CF4. Science Advances.
    7(49), abj8121.
  mla: Heck, Saijoscha, et al. “Attosecond Interferometry of Shape Resonances in the
    Recoil Frame of CF4.” <i>Science Advances</i>, vol. 7, no. 49, abj8121, American
    Association for the Advancement of Science, 2021, doi:<a href="https://doi.org/10.1126/sciadv.abj8121">10.1126/sciadv.abj8121</a>.
  short: S. Heck, D.R. Baykusheva, M. Han, J.-B. Ji, C. Perry, X. Gong, H.J. Wörner,
    Science Advances 7 (2021).
date_created: 2023-08-09T13:09:02Z
date_published: 2021-12-03T00:00:00Z
date_updated: 2023-08-22T07:30:25Z
day: '03'
doi: 10.1126/sciadv.abj8121
extern: '1'
external_id:
  pmid:
  - '34860540'
intvolume: '         7'
issue: '49'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1126/sciadv.abj8121
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Attosecond interferometry of shape resonances in the recoil frame of CF4
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2021'
...
---
_id: '8986'
abstract:
- lang: eng
  text: 'Flowering plants display the highest diversity among plant species and have
    notably shaped terrestrial landscapes. Nonetheless, the evolutionary origin of
    their unprecedented morphological complexity remains largely an enigma. Here,
    we show that the coevolution of cis-regulatory and coding regions of PIN-FORMED
    (PIN) auxin transporters confined their expression to certain cell types and directed
    their subcellular localization to particular cell sides, which together enabled
    dynamic auxin gradients across tissues critical to the complex architecture of
    flowering plants. Extensive intraspecies and interspecies genetic complementation
    experiments with PINs from green alga up to flowering plant lineages showed that
    PIN genes underwent three subsequent, critical evolutionary innovations and thus
    acquired a triple function to regulate the development of three essential components
    of the flowering plant Arabidopsis: shoot/root, inflorescence, and floral organ.
    Our work highlights the critical role of functional innovations within the PIN
    gene family as essential prerequisites for the origin of flowering plants.'
acknowledgement: 'We thank C.Löhne (Botanic Gardens, University of Bonn) for providing
  us with A. trichopoda. We would like to thank T.Han, A.Mally (IST, Austria), and
  C.Hartinger (University of Oxford) for constructive comment and careful reading.
  Funding: The research leading to these results has received funding from the European
  Union’s Horizon 2020 Research and Innovation Programme (ERC grant agreement number
  742985), Austrian Science Fund (FWF, grant number I 3630-B25), DOC Fellowship of
  the Austrian Academy of Sciences, and IST Fellow program. '
article_number: eabc8895
article_processing_charge: No
article_type: original
author:
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: Lesia
  full_name: Rodriguez Solovey, Lesia
  id: 3922B506-F248-11E8-B48F-1D18A9856A87
  last_name: Rodriguez Solovey
  orcid: 0000-0002-7244-7237
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: Xixi
  full_name: Zhang, Xixi
  id: 61A66458-47E9-11EA-85BA-8AEAAF14E49A
  last_name: Zhang
  orcid: 0000-0001-7048-4627
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Zhang Y, Rodriguez Solovey L, Li L, Zhang X, Friml J. Functional innovations
    of PIN auxin transporters mark crucial evolutionary transitions during rise of
    flowering plants. <i>Science Advances</i>. 2020;6(50). doi:<a href="https://doi.org/10.1126/sciadv.abc8895">10.1126/sciadv.abc8895</a>
  apa: Zhang, Y., Rodriguez Solovey, L., Li, L., Zhang, X., &#38; Friml, J. (2020).
    Functional innovations of PIN auxin transporters mark crucial evolutionary transitions
    during rise of flowering plants. <i>Science Advances</i>. AAAS. <a href="https://doi.org/10.1126/sciadv.abc8895">https://doi.org/10.1126/sciadv.abc8895</a>
  chicago: Zhang, Yuzhou, Lesia Rodriguez Solovey, Lanxin Li, Xixi Zhang, and Jiří
    Friml. “Functional Innovations of PIN Auxin Transporters Mark Crucial Evolutionary
    Transitions during Rise of Flowering Plants.” <i>Science Advances</i>. AAAS, 2020.
    <a href="https://doi.org/10.1126/sciadv.abc8895">https://doi.org/10.1126/sciadv.abc8895</a>.
  ieee: Y. Zhang, L. Rodriguez Solovey, L. Li, X. Zhang, and J. Friml, “Functional
    innovations of PIN auxin transporters mark crucial evolutionary transitions during
    rise of flowering plants,” <i>Science Advances</i>, vol. 6, no. 50. AAAS, 2020.
  ista: Zhang Y, Rodriguez Solovey L, Li L, Zhang X, Friml J. 2020. Functional innovations
    of PIN auxin transporters mark crucial evolutionary transitions during rise of
    flowering plants. Science Advances. 6(50), eabc8895.
  mla: Zhang, Yuzhou, et al. “Functional Innovations of PIN Auxin Transporters Mark
    Crucial Evolutionary Transitions during Rise of Flowering Plants.” <i>Science
    Advances</i>, vol. 6, no. 50, eabc8895, AAAS, 2020, doi:<a href="https://doi.org/10.1126/sciadv.abc8895">10.1126/sciadv.abc8895</a>.
  short: Y. Zhang, L. Rodriguez Solovey, L. Li, X. Zhang, J. Friml, Science Advances
    6 (2020).
date_created: 2021-01-03T23:01:23Z
date_published: 2020-12-11T00:00:00Z
date_updated: 2024-10-29T10:22:43Z
day: '11'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1126/sciadv.abc8895
ec_funded: 1
external_id:
  isi:
  - '000599903600014'
  pmid:
  - '33310852'
file:
- access_level: open_access
  checksum: 5ac2500b191c08ef6dab5327f40ff663
  content_type: application/pdf
  creator: dernst
  date_created: 2021-01-07T12:44:33Z
  date_updated: 2021-01-07T12:44:33Z
  file_id: '8994'
  file_name: 2020_ScienceAdvances_Zhang.pdf
  file_size: 10578145
  relation: main_file
  success: 1
file_date_updated: 2021-01-07T12:44:33Z
has_accepted_license: '1'
intvolume: '         6'
isi: 1
issue: '50'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
- _id: 26B4D67E-B435-11E9-9278-68D0E5697425
  grant_number: '25351'
  name: 'A Case Study of Plant Growth Regulation: Molecular Mechanism of Auxin-mediated
    Rapid Growth Inhibition in Arabidopsis Root'
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: AAAS
quality_controlled: '1'
related_material:
  record:
  - id: '10083'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Functional innovations of PIN auxin transporters mark crucial evolutionary
  transitions during rise of flowering plants
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 6
year: '2020'
...
---
_id: '15057'
abstract:
- lang: eng
  text: Vaccinia virus–related kinase (VRK) is an evolutionarily conserved nuclear
    protein kinase. VRK-1, the single Caenorhabditis elegans VRK ortholog, functions
    in cell division and germline proliferation. However, the role of VRK-1 in postmitotic
    cells and adult life span remains unknown. Here, we show that VRK-1 increases
    organismal longevity by activating the cellular energy sensor, AMP-activated protein
    kinase (AMPK), via direct phosphorylation. We found that overexpression of vrk-1
    in the soma of adult C. elegans increased life span and, conversely, inhibition
    of vrk-1 decreased life span. In addition, vrk-1 was required for longevity conferred
    by mutations that inhibit C. elegans mitochondrial respiration, which requires
    AMPK. VRK-1 directly phosphorylated and up-regulated AMPK in both C. elegans and
    cultured human cells. Thus, our data show that the somatic nuclear kinase, VRK-1,
    promotes longevity through AMPK activation, and this function appears to be conserved
    between C. elegans and humans.
acknowledgement: 'This research was supported by grants NRF-2019R1A3B2067745 and NRF-2017R1A5A1015366
  funded by the Korean Government (MSIT) through the National Research Foundation
  (NRF) of Korea to S.-J.V.L. and by grant Basic Science Research Program (No. 2019R1A2C2009440)
  funded by the Korean Government (MSIT) through the NRF of Korea to K.-T.K. '
article_number: aaw7824
article_processing_charge: No
article_type: original
author:
- first_name: Sangsoon
  full_name: Park, Sangsoon
  last_name: Park
- first_name: Murat
  full_name: Artan, Murat
  id: C407B586-6052-11E9-B3AE-7006E6697425
  last_name: Artan
  orcid: 0000-0001-8945-6992
- first_name: Seung Hyun
  full_name: Han, Seung Hyun
  last_name: Han
- first_name: Hae-Eun H.
  full_name: Park, Hae-Eun H.
  last_name: Park
- first_name: Yoonji
  full_name: Jung, Yoonji
  last_name: Jung
- first_name: Ara B.
  full_name: Hwang, Ara B.
  last_name: Hwang
- first_name: Won Sik
  full_name: Shin, Won Sik
  last_name: Shin
- first_name: Kyong-Tai
  full_name: Kim, Kyong-Tai
  last_name: Kim
- first_name: Seung-Jae V.
  full_name: Lee, Seung-Jae V.
  last_name: Lee
citation:
  ama: Park S, Artan M, Han SH, et al. VRK-1 extends life span by activation of AMPK
    via phosphorylation. <i>Science Advances</i>. 2020;6(27). doi:<a href="https://doi.org/10.1126/sciadv.aaw7824">10.1126/sciadv.aaw7824</a>
  apa: Park, S., Artan, M., Han, S. H., Park, H.-E. H., Jung, Y., Hwang, A. B., …
    Lee, S.-J. V. (2020). VRK-1 extends life span by activation of AMPK via phosphorylation.
    <i>Science Advances</i>. American Association for the Advancement of Science.
    <a href="https://doi.org/10.1126/sciadv.aaw7824">https://doi.org/10.1126/sciadv.aaw7824</a>
  chicago: Park, Sangsoon, Murat Artan, Seung Hyun Han, Hae-Eun H. Park, Yoonji Jung,
    Ara B. Hwang, Won Sik Shin, Kyong-Tai Kim, and Seung-Jae V. Lee. “VRK-1 Extends
    Life Span by Activation of AMPK via Phosphorylation.” <i>Science Advances</i>.
    American Association for the Advancement of Science, 2020. <a href="https://doi.org/10.1126/sciadv.aaw7824">https://doi.org/10.1126/sciadv.aaw7824</a>.
  ieee: S. Park <i>et al.</i>, “VRK-1 extends life span by activation of AMPK via
    phosphorylation,” <i>Science Advances</i>, vol. 6, no. 27. American Association
    for the Advancement of Science, 2020.
  ista: Park S, Artan M, Han SH, Park H-EH, Jung Y, Hwang AB, Shin WS, Kim K-T, Lee
    S-JV. 2020. VRK-1 extends life span by activation of AMPK via phosphorylation.
    Science Advances. 6(27), aaw7824.
  mla: Park, Sangsoon, et al. “VRK-1 Extends Life Span by Activation of AMPK via Phosphorylation.”
    <i>Science Advances</i>, vol. 6, no. 27, aaw7824, American Association for the
    Advancement of Science, 2020, doi:<a href="https://doi.org/10.1126/sciadv.aaw7824">10.1126/sciadv.aaw7824</a>.
  short: S. Park, M. Artan, S.H. Han, H.-E.H. Park, Y. Jung, A.B. Hwang, W.S. Shin,
    K.-T. Kim, S.-J.V. Lee, Science Advances 6 (2020).
date_created: 2024-03-04T09:41:57Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2024-03-04T09:52:09Z
day: '01'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.1126/sciadv.aaw7824
file:
- access_level: open_access
  checksum: a37157cd0de709dce5fe03f4a31cd0b6
  content_type: application/pdf
  creator: dernst
  date_created: 2024-03-04T09:46:41Z
  date_updated: 2024-03-04T09:46:41Z
  file_id: '15058'
  file_name: 2020_ScienceAdvances_Park.pdf
  file_size: 1864415
  relation: main_file
  success: 1
file_date_updated: 2024-03-04T09:46:41Z
has_accepted_license: '1'
intvolume: '         6'
issue: '27'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
status: public
title: VRK-1 extends life span by activation of AMPK via phosphorylation
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2020'
...