---
_id: '13968'
abstract:
- lang: eng
  text: The use of multimodal readout mechanisms next to label-free real-time monitoring
    of biomolecular interactions can provide valuable insight into surface-based reaction
    mechanisms. To this end, the combination of an electrolyte-gated field-effect
    transistor (EG-FET) with a fiber optic-coupled surface plasmon resonance (FO-SPR)
    probe serving as gate electrode has been investigated to deconvolute surface mass
    and charge density variations associated to surface reactions. However, applying
    an electrochemical potential on such gold-coated FO-SPR gate electrodes can induce
    gradual morphological changes of the thin gold film, leading to an irreversible
    blue-shift of the SPR wavelength and a substantial signal drift. We show that
    mild annealing leads to optical and electronic signal stabilization (20-fold lower
    signal drift than as-sputtered fiber optic gates) and improved overall analytical
    performance characteristics. The thermal treatment prevents morphological changes
    of the thin gold-film occurring during operation, hence providing reliable and
    stable data immediately upon gate voltage application. Thus, the readout output
    of both transducing principles, the optical FO-SPR and electronic EG-FET, stays
    constant throughout the whole sensing time-window and the long-term effect of
    thermal treatment is also improved, providing stable signals even after 1 year
    of storage. Annealing should therefore be considered a necessary modification
    for applying fiber optic gate electrodes in real-time multimodal investigations
    of surface reactions at the solid-liquid interface.
acknowledged_ssus:
- _id: EM-Fac
acknowledgement: "This project has received funding from the European Union’s Horizon
  2020 Research and Innovation Programme under the Marie Skłodowska-Curie grant agreement
  No. 813863–BORGES. We further thank the office of the Federal Government of Lower
  Austria, K3-Group–Culture, Science and Education, for their financial support as
  part of the project “Responsive Wound Dressing”. We gratefully acknowledge the financial
  support from the Austrian Research Promotion Agency (FFG; 888067).\r\nWe thank the
  Electron Microscopy Facility at IST Austria for their support with sputter coating
  the FO tips and Bernhard Pichler from AIT for software development to facilitate
  data evaluation."
article_number: '1202132'
article_processing_charge: Yes
article_type: original
author:
- first_name: Roger
  full_name: Hasler, Roger
  last_name: Hasler
- first_name: Marie Helene
  full_name: Steger-Polt, Marie Helene
  last_name: Steger-Polt
- first_name: Ciril
  full_name: Reiner-Rozman, Ciril
  last_name: Reiner-Rozman
- first_name: Stefan
  full_name: Fossati, Stefan
  last_name: Fossati
- first_name: Seungho
  full_name: Lee, Seungho
  id: BB243B88-D767-11E9-B658-BC13E6697425
  last_name: Lee
  orcid: 0000-0002-6962-8598
- first_name: Patrik
  full_name: Aspermair, Patrik
  last_name: Aspermair
- first_name: Christoph
  full_name: Kleber, Christoph
  last_name: Kleber
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Jakub
  full_name: Dostalek, Jakub
  last_name: Dostalek
- first_name: Wolfgang
  full_name: Knoll, Wolfgang
  last_name: Knoll
citation:
  ama: 'Hasler R, Steger-Polt MH, Reiner-Rozman C, et al. Optical and electronic signal
    stabilization of plasmonic fiber optic gate electrodes: Towards improved real-time
    dual-mode biosensing. <i>Frontiers in Physics</i>. 2023;11. doi:<a href="https://doi.org/10.3389/fphy.2023.1202132">10.3389/fphy.2023.1202132</a>'
  apa: 'Hasler, R., Steger-Polt, M. H., Reiner-Rozman, C., Fossati, S., Lee, S., Aspermair,
    P., … Knoll, W. (2023). Optical and electronic signal stabilization of plasmonic
    fiber optic gate electrodes: Towards improved real-time dual-mode biosensing.
    <i>Frontiers in Physics</i>. Frontiers. <a href="https://doi.org/10.3389/fphy.2023.1202132">https://doi.org/10.3389/fphy.2023.1202132</a>'
  chicago: 'Hasler, Roger, Marie Helene Steger-Polt, Ciril Reiner-Rozman, Stefan Fossati,
    Seungho Lee, Patrik Aspermair, Christoph Kleber, Maria Ibáñez, Jakub Dostalek,
    and Wolfgang Knoll. “Optical and Electronic Signal Stabilization of Plasmonic
    Fiber Optic Gate Electrodes: Towards Improved Real-Time Dual-Mode Biosensing.”
    <i>Frontiers in Physics</i>. Frontiers, 2023. <a href="https://doi.org/10.3389/fphy.2023.1202132">https://doi.org/10.3389/fphy.2023.1202132</a>.'
  ieee: 'R. Hasler <i>et al.</i>, “Optical and electronic signal stabilization of
    plasmonic fiber optic gate electrodes: Towards improved real-time dual-mode biosensing,”
    <i>Frontiers in Physics</i>, vol. 11. Frontiers, 2023.'
  ista: 'Hasler R, Steger-Polt MH, Reiner-Rozman C, Fossati S, Lee S, Aspermair P,
    Kleber C, Ibáñez M, Dostalek J, Knoll W. 2023. Optical and electronic signal stabilization
    of plasmonic fiber optic gate electrodes: Towards improved real-time dual-mode
    biosensing. Frontiers in Physics. 11, 1202132.'
  mla: 'Hasler, Roger, et al. “Optical and Electronic Signal Stabilization of Plasmonic
    Fiber Optic Gate Electrodes: Towards Improved Real-Time Dual-Mode Biosensing.”
    <i>Frontiers in Physics</i>, vol. 11, 1202132, Frontiers, 2023, doi:<a href="https://doi.org/10.3389/fphy.2023.1202132">10.3389/fphy.2023.1202132</a>.'
  short: R. Hasler, M.H. Steger-Polt, C. Reiner-Rozman, S. Fossati, S. Lee, P. Aspermair,
    C. Kleber, M. Ibáñez, J. Dostalek, W. Knoll, Frontiers in Physics 11 (2023).
date_created: 2023-08-06T22:01:11Z
date_published: 2023-07-14T00:00:00Z
date_updated: 2023-12-13T12:04:10Z
day: '14'
ddc:
- '530'
department:
- _id: MaIb
doi: 10.3389/fphy.2023.1202132
external_id:
  isi:
  - '001038636400001'
file:
- access_level: open_access
  checksum: fb36dda665e57bab006a000bf0faacd5
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-07T07:48:11Z
  date_updated: 2023-08-07T07:48:11Z
  file_id: '13978'
  file_name: 2023_FrontiersPhysics_Hasler.pdf
  file_size: 2421758
  relation: main_file
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file_date_updated: 2023-08-07T07:48:11Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Frontiers in Physics
publication_identifier:
  eissn:
  - 2296-424X
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Optical and electronic signal stabilization of plasmonic fiber optic gate
  electrodes: Towards improved real-time dual-mode biosensing'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2023'
...