---
_id: '7204'
abstract:
- lang: eng
  text: Plant root architecture dynamically adapts to various environmental conditions,
    such as salt‐containing soil. The phytohormone abscisic acid (ABA) is involved
    among others also in these developmental adaptations, but the underlying molecular
    mechanism remains elusive. Here, a novel branch of the ABA signaling pathway in
    Arabidopsis involving PYR/PYL/RCAR (abbreviated as PYLs) receptor‐protein phosphatase
    2A (PP2A) complex that acts in parallel to the canonical PYLs‐protein phosphatase
    2C (PP2C) mechanism is identified. The PYLs‐PP2A signaling modulates root gravitropism
    and lateral root formation through regulating phytohormone auxin transport. In
    optimal conditions, PYLs ABA receptor interacts with the catalytic subunits of
    PP2A, increasing their phosphatase activity and thus counteracting PINOID (PID)
    kinase‐mediated phosphorylation of PIN‐FORMED (PIN) auxin transporters. By contrast,
    in salt and osmotic stress conditions, ABA binds to PYLs, inhibiting the PP2A
    activity, which leads to increased PIN phosphorylation and consequently modulated
    directional auxin transport leading to adapted root architecture. This work reveals
    an adaptive mechanism that may flexibly adjust plant root growth to withstand
    saline and osmotic stresses. It occurs via the cross‐talk between the stress hormone
    ABA and the versatile developmental regulator auxin.
article_number: '1901455'
article_processing_charge: No
article_type: original
author:
- first_name: Yang
  full_name: Li, Yang
  last_name: Li
- first_name: Yaping
  full_name: Wang, Yaping
  last_name: Wang
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: Zhen
  full_name: Li, Zhen
  last_name: Li
- first_name: Zhi
  full_name: Yuan, Zhi
  last_name: Yuan
- first_name: Matous
  full_name: Glanc, Matous
  id: 1AE1EA24-02D0-11E9-9BAA-DAF4881429F2
  last_name: Glanc
  orcid: 0000-0003-0619-7783
- first_name: David
  full_name: Domjan, David
  id: C684CD7A-257E-11EA-9B6F-D8588B4F947F
  last_name: Domjan
  orcid: 0000-0003-2267-106X
- first_name: Kai
  full_name: Wang, Kai
  last_name: Wang
- first_name: Wei
  full_name: Xuan, Wei
  last_name: Xuan
- first_name: Yan
  full_name: Guo, Yan
  last_name: Guo
- first_name: Zhizhong
  full_name: Gong, Zhizhong
  last_name: Gong
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Jing
  full_name: Zhang, Jing
  last_name: Zhang
citation:
  ama: Li Y, Wang Y, Tan S, et al. Root growth adaptation is mediated by PYLs ABA
    receptor-PP2A protein phosphatase complex. <i>Advanced Science</i>. 2020;7(3).
    doi:<a href="https://doi.org/10.1002/advs.201901455">10.1002/advs.201901455</a>
  apa: Li, Y., Wang, Y., Tan, S., Li, Z., Yuan, Z., Glanc, M., … Zhang, J. (2020).
    Root growth adaptation is mediated by PYLs ABA receptor-PP2A protein phosphatase
    complex. <i>Advanced Science</i>. Wiley. <a href="https://doi.org/10.1002/advs.201901455">https://doi.org/10.1002/advs.201901455</a>
  chicago: Li, Yang, Yaping Wang, Shutang Tan, Zhen Li, Zhi Yuan, Matous Glanc, David
    Domjan, et al. “Root Growth Adaptation Is Mediated by PYLs ABA Receptor-PP2A Protein
    Phosphatase Complex.” <i>Advanced Science</i>. Wiley, 2020. <a href="https://doi.org/10.1002/advs.201901455">https://doi.org/10.1002/advs.201901455</a>.
  ieee: Y. Li <i>et al.</i>, “Root growth adaptation is mediated by PYLs ABA receptor-PP2A
    protein phosphatase complex,” <i>Advanced Science</i>, vol. 7, no. 3. Wiley, 2020.
  ista: Li Y, Wang Y, Tan S, Li Z, Yuan Z, Glanc M, Domjan D, Wang K, Xuan W, Guo
    Y, Gong Z, Friml J, Zhang J. 2020. Root growth adaptation is mediated by PYLs
    ABA receptor-PP2A protein phosphatase complex. Advanced Science. 7(3), 1901455.
  mla: Li, Yang, et al. “Root Growth Adaptation Is Mediated by PYLs ABA Receptor-PP2A
    Protein Phosphatase Complex.” <i>Advanced Science</i>, vol. 7, no. 3, 1901455,
    Wiley, 2020, doi:<a href="https://doi.org/10.1002/advs.201901455">10.1002/advs.201901455</a>.
  short: Y. Li, Y. Wang, S. Tan, Z. Li, Z. Yuan, M. Glanc, D. Domjan, K. Wang, W.
    Xuan, Y. Guo, Z. Gong, J. Friml, J. Zhang, Advanced Science 7 (2020).
date_created: 2019-12-22T23:00:43Z
date_published: 2020-02-05T00:00:00Z
date_updated: 2023-08-17T14:13:17Z
day: '05'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1002/advs.201901455
external_id:
  isi:
  - '000501912800001'
  pmid:
  - '32042554'
file:
- access_level: open_access
  checksum: 016eeab5860860af038e2da95ffe75c3
  content_type: application/pdf
  creator: dernst
  date_created: 2020-02-24T14:29:54Z
  date_updated: 2020-07-14T12:47:53Z
  file_id: '7519'
  file_name: 2020_AdvScience_Li.pdf
  file_size: 3586924
  relation: main_file
file_date_updated: 2020-07-14T12:47:53Z
has_accepted_license: '1'
intvolume: '         7'
isi: 1
issue: '3'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Advanced Science
publication_identifier:
  eissn:
  - 2198-3844
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Root growth adaptation is mediated by PYLs ABA receptor-PP2A protein phosphatase
  complex
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 7
year: '2020'
...