---
_id: '13391'
abstract:
- lang: eng
  text: 'It is reported that spiropyran—a widely investigated molecular photoswitch—can
    be stabilized in aqueous environments in the presence of a variety of proteins,
    including human serum albumin, insulin fibrils, lysozyme, and glucose oxidase.
    The optical properties of the complexed photoswitch are protein dependent, with
    human serum albumin providing the spiropyran with emission features previously
    observed for a photoswitch confined in media of high viscosity. Despite being
    bound to the protein molecules, spiropyran can undergo a ring-opening reaction
    upon exposure to UV light. This photoisomerization process can affect the properties
    of the proteins: here, it is shown that the electrical conduction through human
    serum albumin to which the spiropyran is bound increases following the ring-opening
    reaction.'
article_processing_charge: No
article_type: original
author:
- first_name: Nadav
  full_name: Amdursky, Nadav
  last_name: Amdursky
- first_name: Pintu K.
  full_name: Kundu, Pintu K.
  last_name: Kundu
- first_name: Johannes
  full_name: Ahrens, Johannes
  last_name: Ahrens
- first_name: Dan
  full_name: Huppert, Dan
  last_name: Huppert
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
citation:
  ama: Amdursky N, Kundu PK, Ahrens J, Huppert D, Klajn R. Noncovalent interactions
    with proteins modify the physicochemical properties of a molecular switch. <i>ChemPlusChem</i>.
    2016;81(1):44-48. doi:<a href="https://doi.org/10.1002/cplu.201500417">10.1002/cplu.201500417</a>
  apa: Amdursky, N., Kundu, P. K., Ahrens, J., Huppert, D., &#38; Klajn, R. (2016).
    Noncovalent interactions with proteins modify the physicochemical properties of
    a molecular switch. <i>ChemPlusChem</i>. Wiley. <a href="https://doi.org/10.1002/cplu.201500417">https://doi.org/10.1002/cplu.201500417</a>
  chicago: Amdursky, Nadav, Pintu K. Kundu, Johannes Ahrens, Dan Huppert, and Rafal
    Klajn. “Noncovalent Interactions with Proteins Modify the Physicochemical Properties
    of a Molecular Switch.” <i>ChemPlusChem</i>. Wiley, 2016. <a href="https://doi.org/10.1002/cplu.201500417">https://doi.org/10.1002/cplu.201500417</a>.
  ieee: N. Amdursky, P. K. Kundu, J. Ahrens, D. Huppert, and R. Klajn, “Noncovalent
    interactions with proteins modify the physicochemical properties of a molecular
    switch,” <i>ChemPlusChem</i>, vol. 81, no. 1. Wiley, pp. 44–48, 2016.
  ista: Amdursky N, Kundu PK, Ahrens J, Huppert D, Klajn R. 2016. Noncovalent interactions
    with proteins modify the physicochemical properties of a molecular switch. ChemPlusChem.
    81(1), 44–48.
  mla: Amdursky, Nadav, et al. “Noncovalent Interactions with Proteins Modify the
    Physicochemical Properties of a Molecular Switch.” <i>ChemPlusChem</i>, vol. 81,
    no. 1, Wiley, 2016, pp. 44–48, doi:<a href="https://doi.org/10.1002/cplu.201500417">10.1002/cplu.201500417</a>.
  short: N. Amdursky, P.K. Kundu, J. Ahrens, D. Huppert, R. Klajn, ChemPlusChem 81
    (2016) 44–48.
date_created: 2023-08-01T09:43:46Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2023-08-07T12:51:56Z
day: '01'
doi: 10.1002/cplu.201500417
extern: '1'
external_id:
  pmid:
  - '31968727'
intvolume: '        81'
issue: '1'
keyword:
- General Chemistry
language:
- iso: eng
month: '01'
oa_version: None
page: 44-48
pmid: 1
publication: ChemPlusChem
publication_identifier:
  eissn:
  - 2192-6506
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Noncovalent interactions with proteins modify the physicochemical properties
  of a molecular switch
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 81
year: '2016'
...