---
_id: '6559'
abstract:
- lang: eng
  text: Branching morphogenesis is a prototypical example of complex three-dimensional
    organ sculpting, required in multiple developmental settings to maximize the area
    of exchange surfaces. It requires, in particular, the coordinated growth of different
    cell types together with complex patterning to lead to robust macroscopic outputs.
    In recent years, novel multiscale quantitative biology approaches, together with
    biophysical modelling, have begun to shed new light of this topic. Here, we wish
    to review some of these recent developments, highlighting the generic design principles
    that can be abstracted across different branched organs, as well as the implications
    for the broader fields of stem cell, developmental and systems biology.
article_processing_charge: No
article_type: original
author:
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Benjamin D.
  full_name: Simons, Benjamin D.
  last_name: Simons
citation:
  ama: Hannezo EB, Simons BD. Multiscale dynamics of branching morphogenesis. <i>Current
    Opinion in Cell Biology</i>. 2019;60:99-105. doi:<a href="https://doi.org/10.1016/j.ceb.2019.04.008">10.1016/j.ceb.2019.04.008</a>
  apa: Hannezo, E. B., &#38; Simons, B. D. (2019). Multiscale dynamics of branching
    morphogenesis. <i>Current Opinion in Cell Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.ceb.2019.04.008">https://doi.org/10.1016/j.ceb.2019.04.008</a>
  chicago: Hannezo, Edouard B, and Benjamin D. Simons. “Multiscale Dynamics of Branching
    Morphogenesis.” <i>Current Opinion in Cell Biology</i>. Elsevier, 2019. <a href="https://doi.org/10.1016/j.ceb.2019.04.008">https://doi.org/10.1016/j.ceb.2019.04.008</a>.
  ieee: E. B. Hannezo and B. D. Simons, “Multiscale dynamics of branching morphogenesis,”
    <i>Current Opinion in Cell Biology</i>, vol. 60. Elsevier, pp. 99–105, 2019.
  ista: Hannezo EB, Simons BD. 2019. Multiscale dynamics of branching morphogenesis.
    Current Opinion in Cell Biology. 60, 99–105.
  mla: Hannezo, Edouard B., and Benjamin D. Simons. “Multiscale Dynamics of Branching
    Morphogenesis.” <i>Current Opinion in Cell Biology</i>, vol. 60, Elsevier, 2019,
    pp. 99–105, doi:<a href="https://doi.org/10.1016/j.ceb.2019.04.008">10.1016/j.ceb.2019.04.008</a>.
  short: E.B. Hannezo, B.D. Simons, Current Opinion in Cell Biology 60 (2019) 99–105.
date_created: 2019-06-16T21:59:12Z
date_published: 2019-10-01T00:00:00Z
date_updated: 2023-08-28T09:38:57Z
day: '01'
department:
- _id: EdHa
doi: 10.1016/j.ceb.2019.04.008
external_id:
  isi:
  - '000486545800014'
  pmid:
  - '31181348'
intvolume: '        60'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
page: 99-105
pmid: 1
publication: Current Opinion in Cell Biology
publication_identifier:
  eissn:
  - '18790410'
  issn:
  - '09550674'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Multiscale dynamics of branching morphogenesis
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 60
year: '2019'
...